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terbinafine (lamisil) therapy for microsporum canis scalp ringworm. 19989861751
onychomycosis due to microsporum gypseum.the first four cases of onychomycosis due to microsporum gypseum observed in italy between 1990 and 1997 are reported. clinical manifestation was distal subungual onychomycosis in all cases. the lesions were asymptomatic in two patients. three patients were treated with oral itraconazole (pulsed therapy) and the other with ciclopirox 8% nail lacquer. clinical and mycological recovery was achieved in all cases. the cases are reported because of their rarity.19989861844
dermatophytoses among school children in aba, abia state--nigeria and some physiological studies on the isolated etiologic agents.a total of 1,136 school children comprising 433 males and 703 females, within the age groups 4 to 16 years and all resident in aba municipal town of abia state were examined for clinical signs of dermatophytoses. out of this number examined 196 (17.3%), which included 108 males and 88 females, had clinical lesions on various parts of the body including the head, skin, finger nails and toe webs characteristic of dermatophytoses. while the infection occurred highest among children between the ages ...19989842165
plants used in guatemala for the treatment of protozoal infections. i. screening of activity to bacteria, fungi and american trypanosomes of 13 native plants.extracts were prepared from 13 native plants used for the treatment of protozoal infections. activity against bacteria and fungi was demonstrated by dilution procedures; trypanosoma cruzi was evaluated in vitro against epimastigote and trypomastigotes and in vivo against trypomastigotes. in active extracts, toxicity was evaluated by artemia salina nauplii, oral acute toxicity (1-5 g/kg) and oral and intraperitoneal subacute toxicity in mice (500 mg/kg). from the plants screened, six showed activ ...19989849628
an outbreak of a mixed infection of dermatophilus congolensis and microsporum gypseum in camels (camelus dromedarius) in saudi arabia.although both dermatophilus congolensis and microsporum gypseum infections have been reported separately in camels, mixed infection involving both agents has not been reported to date. the authors describe a mixed infection of d. congolensis and m. gypseum in camels reared on a dairy farm in saudi arabia. a total of 131 out of 559 camels (23.4%) were affected. forty-eight camels less than one year of age had discrete, circumscribed, crusty, hairless lesions, found in particular on the neck and f ...19989850546
dermatophytes isolated from selected ruminants in india.a survey was carried out in different areas of uttar pradesh for isolating and identifying dermatophytes from ruminants. out of 102 skin scrapings, collected from various animals, 4/22 cattle, 1/9 buffalo, 14/44 sheep and 2/28 goats were koh positive. in respect of the cattle, the culture positive samples yielded one strain each of trichophyton mentagrophytes, t. rubrum, t. simii and two strains of microsporum gypseum. from the buffaloes examined, only one case yielded a dermatophyte and it was ...19989850594
[dermatophytosis in the greater resistencia area, chaco province, argentina].epidemiological characteristics of dermatophytoses in the metropolitan area of resistencia city are described. hair fragments, skin, scalp or nail scrapings were collected from 3.507 persons with dermatological symptoms of probable fungal origin. the mycological studies were performed by three mycological laboratories, one from a university institute and two from private laboratories. direct microscopic examinations showed fungi in 39.66% of samples, while the recovering of dermatophytes from cu ...19989744034
frequency of dermatophytes in the metropolitan area of porto alegre, rs, brazil.in order to evaluate the distribution of dermatophytes in porto alegre, the capital of the state of rio grande do sul, brazil, they were isolated from the skin, hairs and nails samples and retrospectively analyzed from june 1981 to june 1995, in two different institutions in the city of porto alegre: (i) the serviço de micologia do instituto de pesquisas biológicas jandyr maya faillace, da secretaria de saúde e meio ambiente do rio grande do sul which attends the low income population (low and m ...19989755559
itraconazole oral solution for the treatment of tinea capitis.twenty-seven children (12 boys, 15 girls, age range 3-11 years, weight range 10-40 kg) were treated with itraconazole oral solution 10 mg/ml given as pulse therapy for tinea capitis. the dosage regimen was 3 mg/kg per day given once daily in a fasting state with each pulse lasting 1 week. the first two pulses were separated by a 2-week off-drug period, and the second and third pulses had a 3-week period without drug between them. for each patient a second and third pulse were administered if the ...19989764158
increased incidence of trichophyton tonsurans tinea capitis in ontario, canada between 1985 and 1996.in canada, since the 1990s, trichophyton tonsurans has emerged as the main cause of tinea capitis. prior to this the more common agents were t. verrucosum, microsporum canis and m. audouinii. over the past few years the incidence of t. tonsurans has increased such that in 1985 and 1996 the cases of mycologically confirmed tinea capitis due to t. tonsurans were 9% and 76%, respectively. the epidemic of t. tonsurans has reduced the role of wood's lamp in diagnosis of tinea capitis. the age distrib ...19989776814
comments on microsporum canis. 19989776843
response to 'comments on microsporum canis' 19989776844
efficacy of oral administration of itraconazole to cats with dermatophytosis caused by microsporum canis.to determine efficacy of orally administered itraconazole in cats with dermatophytosis caused by microsporum canis.19989776995
efficacy and safety of itraconazole pulse therapy: brazilian multicentric study on toenail onychomycosis caused by dermatophytes.itraconazole is a large spectrum triazole with known efficacy in both continuous and pulse therapy for various mycoses.19989784035
efficacy, safety and tolerability of terbinafine for tinea capitis in children: brazilian multicentric study with daily oral tablets for 1,2 and 4 weeks.tinea capitis is a common skin disease seen predominantly in children. the standard therapies for this disease are griseofulvin and ketoconazole. nevertheless, these drugs have drawbacks in that they are only fungistatic and require treatment for at least 6 weeks. previous studies with oral terbinafine for the treatment of tinea capitis have shown that this agent is effective when given for 4 weeks, comparable to an 8-week regimen with griseofulvin. to date there is no data on the use of oral te ...19989784040
1998 william j. stickel bronze award. antifungal activity of melaleuca alternifolia (tea-tree) oil against various pathogenic organisms.tea-tree oil (oil of melaleuca alternifolia) has recently received much attention as a natural remedy for bacterial and fungal infections of the skin and mucosa. as with most naturally occurring agents, claims of effectiveness have been only anecdotal; however, several published studies have recently demonstrated tea-tree oil's antibacterial activity. this study was conducted to determine the activity of tea-tree oil against 58 clinical isolates: candida albicans (n = 10), trichophyton rubrum (n ...19989791953
ecology of cycloheximide-resistant fungi in field soils receiving raw city wastewater or normal irrigation water.the effect of raw city wastewater irrigation on biodiversity and population densities of a cycloheximide-resistant (ch) fungal community was studied in 13 field soils receiving either raw city wastewater or normal irrigation, and in raw city wastewater in the nablus area, using the hair baiting technique (hbt) and a surface soil dilution plating (ssdp) technique. three of these fields [one had been receiving raw city wastewater for more than ten years and was designated a heavily polluted field, ...199810422272
[comparative molecular field analysis(comfa) of allylamine and benzylamine antimycotics]."active analog approach" has been employed to search the pharmacophoric conformation of the allylamine and benzylamine antimycotics. a local minimum energy conformation, which is very similar to the crystallographically determined coordinate of naftifine or terbinafine, has been applied to build all compounds. comparative molecular field analysis (comfa) has been used to examine the correlations between the activities against 6 common human pathogenic fungi and the physicochemical properties of ...199811938964
antimicrobial effects of aqueous plant extracts on the fungi microsporum canis and trichophyton rubrum and on three bacterial species.aqueous extracts of 10 plants were tested for their ability to inhibit trichophyton rubrum and microsporum canis, the aetiological agents of dermal fungal infections in humans. these extracts were also evaluated for their activity against some bacteria. aqueous extracts from the leaves of inula viscosa produced detectable antifungal activity against these dermatophytes.19989489036
in vitro activity of a new oral triazole, bms-207147 (er-30346)the antifungal activity of bms-207147 (also known as er-30346) was compared to those of itraconazole and fluconazole against 250 strains of fungi representing 44 fungal species. mics were determined by using the national committee for clinical laboratory standards (nccls)-recommended broth macrodilution method for yeasts, which was modified for filamentous fungi. bms-207147 was about two- to fourfold more potent than itraconazole and about 40-fold more active than fluconazole against yeasts. wit ...19989527778
butenafine.butenafine is a new antifungal agent with primary fungicidal activity against dermatophytes such as trichophyton mentagrophytes, microsporum canis and trichophyton rubrum which cause tinea infections. 14c-labelled butenafine (approximately 30 micrograms/g tissue) was found within guinea-pig dorsal skin 24 hours after topical application. most of the drug was distributed into the epidermis including the horny layer. small amounts were found in the dermis, probably transported via sebaceous glands ...19989530545
griseofulvin and terbinafine in the treatment of tinea capitis in children.to compare the effectiveness of griseofulvin and terbinafine in the treatment of tinea capitis in children.19989539918
solution conformation and dynamics of a fungal cell wall polysaccharide isolated from microsporum gypseum.the conformational and dynamical features of a branched mannan isolated from a fungal cell wall have been analysed by homo and heteronuclear nmr methods, employing different magnetic fields. 1h nmr cross relaxation times have been obtained for this polysaccharide and have been interpreted qualitatively using different motional models. 13c nmr relaxation parameters (t1, t2, noe) have also been measured and interpreted using different approximations based on the lipari and szabo model free approac ...19989579809
[two cases of tinea capitis with different clinical courses].we report cases of two 4-year-old boys with tinea capitis who attend the same daynursery. clinically, on the first visit both lesions were a superficial type, however we initiated treatment with a dose of 50 mg/day of oral itraconazole. althougth the lesion of case 2 improved after 11 weeks of treatment, case 1 developed to kerion celsi and required continued treatment for 22 weeks for cure. microsporum canis was isolated from the hairs of both cases and mic of itraconazole against both isolates ...19989580037
an overview of topical antifungal therapy in dermatomycoses. a north american perspective.dermatophytes cause fungal infections of keratinised tissues, e.g. skin, hair and nails. the organisms belong to 3 genera, trichophyton, epidermophyton and microsporum. dermatophytes may be grouped into 3 categories based on host preference and natural habitat. anthropophilic species predominantly infect humans, geophilic species are soil based and may infect both humans and animals, zoophilic species generally infect non-human mammals. it is important to confirm mycologically the clinical diagn ...19989585862
synthesis, antimicrobial activity and bleaching effect of some reaction products of 4-oxo-4h-benzopyran-3-carboxaldehydes with aminobenzothiazoles and hydrazides.the synthesis of the biologically active novel systems derived from reaction of 3-formylchromones with three types of amino derivatives, 6-r2-2-aminobenzothiazoles, 6-amino-2-r3-thiobenzothiazoles and hydrazide derivatives (derived from cyanoacetic, isonicotine, salicylic and gallic acids) was carried out. the structures of the prepared compounds have been proved by elemental analysis, 1h nmr and ir spectra. antimicrobial activity was studied against the following microorganisms--bacteria g+ (st ...19989639869
identification of common dermatophytes (trichophyton, microsporum, epidermophyton) using polymerase chain reactions.polymerase chain reaction (pcr) fingerprinting detected dna polymorphisms among frequently isolated species and strains of the genera trichophyton, microsporum and epidermophyton. the patterns generated by this dna-based method permitted species and strains to be identified. the conventional methods to identify dermatophytes rely on the expression of characteristic morphological features, as well as several physiological properties. identification is often delayed or problematic because isolates ...19989640360
prevalence of undetected tinea capitis in a prospective school survey in madrid: emergence of new causative fungi.from october 1994 to december 1996, a prospective study was undertaken in 10,000 unselected school children in madrid, aged between 2 and 16 years (mean +/- sd 8.5 +/- 3.6 years). fifty-two (0.52%) (including 13 immigrants from africa) had dermatophytes in the scalp: 33 (0.33%) (including 10 immigrants from africa) had tinea capitis and 19 were scalp carriers. almost half of the symptomatic cases were caused by trichophyton tonsurans (12 of 33 cases) and microsporum canis (16 of 33 cases). t. to ...19989640375
the in vitro and in vivo production of a 31.5-kd keratinolytic subtilase from microsporum canis and the clinical status in naturally infected cats.microsporum-canis-infected cats, especially the asymptomatic infected ones, are mainly responsible for the zoonotic disease. the important variability of the clinical signs in cats is poorly understood. recently, a 31.5-kd keratinolytic subtilase was found to be a putative virulence factor.19989669125
identification of clinical isolates of microsporum canis and m. gypseum by random amplification of polymorphic dna (rapd) and southern hybridization analyses.clinical isolates of microsporum canis and m. gypseum from humans, dogs and cats were examined by random amplification of polymorphic dna (rapd) and southern hybridization analyses. the rapd band patterns of six clinical isolates of m. canis were identical to those of standard strains of arthroderma otae. of nine clinical isolates of m. gypseum seven and two isolates showed rapd patterns identical to those of standard strains of a. gypseum and a. incurvatum respectively. southern blot analysis u ...19989670766
kerion celsi: a clinical epidemiological study.we present a case record of patients with kerion celsi observed in the clinic of dermatology, university of cagliari (italy) from 1981 to 1995. altogether, 31 children (18 male and 13 female) with an age range of 40 days to 12 years were studied. in all cases the lesions were confined to the scalp. in 10 cases the disease developed as such, while in 21 patients it represented the inflammatory evolution of tinea capitis secondary to incongruous topical treatment. microsporum canis was isolated in ...19989670770
dermatophytoses in crete, greece, between 1992 and 1996.pathological specimens from 1361 patients with clinical manifestations of dermatophytosis from the island of crete, greece, were examined for dermatophytes during a 5-year period (1992-96). dermatophytes of the genus trichophyton, microsporum and epidermophyton were isolated from 327 (24%) of the patients. trichophyton rubrum was the most frequently isolated dermatophyte accounting for 44.4% of the strains, followed by m. canis (25%), t. mentagrophytes var. interdigitale (14.4%) and e. floccosum ...19989670771
[zoophilic dermatophytes as epizoonoses pathogens and their significance to dermatology].different dermatophytes occurring primarily in animals may be transmissible to man and produce human disease; such zoophilic fungi should be considered a possible cause of skin lesions of unclear origin. several species including trichophyton verrucosum, trichophyton mentagrophytes and microsporum canis may infect human skin, causing a variety of signs and symptoms. people who have close contact to infested cattle or cats are more often exposed to fungal infections. certain professions, such as ...19989675572
a survey of dermatophytes isolated from human patients in the united states from 1993 to 1995.a survey of dermatophytes, isolated from human patients seeking medical attention, was conducted for the years 1993 to 1995. data were collected from 23 states throughout the continental united states and the district of columbia and from 44 to 45 laboratories. these data were compared with the results of two earlier surveys (1979 to 1981 and 1985 to 1987). in contrast to the earlier surveys trichophyton tonsurans became the most frequently isolated dermatophyte (44.9%) followed by t. rubrum (41 ...19989704838
antimicrobial activity of some 1,2-benzisothiazoles having a benzenesulfonamide moiety.some sulfonamide and sulfonylurea derivatives of unsubstituted and 5-methylsubstituted 1,2-benzisothiazole were studied in vitro for their antimicrobial properties against bacteria and fungi. compounds 7 and 8 exhibited good antibacterial activity against gram positive bacteria. a strong synergism was observed when their growth-inhibitory effect was assayed in combination with trimethoprim by using bacillus subtilis and staphylococcus aureus as test microorganisms. the antimycotic action of benz ...19989713255
[dermatomycosis caused by trichophyton verrucosum in mother and child].in recent years, there has been an epidemiological renaissance of zoophilic dermatophytoses caused by a variety of factors. at present, the most important causative organisms are microsporum canis, trichophyton mentagrophytes var. granulosum and, as in the present case, trichophyton verrucosum. these are formerly notifiable pathogens which are highly virulent and contagious. the example of an extensive, originally unrecognized tinea corporis et faciei in mother and child presented here shows the ...19989715387
differentiation of microsporum species by random amplification of polymorphic dna (rapd) and southern hybridization analyses.molecular characterization of 18 species belonging to the genus microsporum isolated from human and animal dermatophytosis was carried out by random amplification of polymorphic dna (rapd) and southern hybridization analyses. all of these 18 microsporum species showed different band patterns specific to each species in rapd analysis. southern hybridization analysis using c3 probe derived from a rapd band from arthroderma otae, teleomorph of m. canis, revealed distinct bands in 14 of the 18 micro ...19989715638
tinea capitis due to microsporum gypseum in an adult.a case of tinea capitis due to microsporum gypseum in an adult is described. an otherwise healthy 69-year-old woman presented two large patches of slightly erythematous scaling alopecia localized on the vertex and on the left parietal region of the scalp. the only subjective sign was itching. a mycological culture was positive for microsporum gypseum. tinea capitis is uncommon in adults; furthermore, isolation of microsporum gypseum from this type of lesion is rare.19989715640
epidemiological study of tinea capitis in schoolchildren in the nablus area (west bank).a study of tinea capitis was carried out during the period january-june 1996 in 7525 primary schoolchildren aged 6-14 years comprising 4050 boys and 3475 girls in the nablus district in the palestinian area. fourteen primary schools located in rural, urban and refugee camp areas were surveyed in this study. seventy-five (1.0%) mycologically proven cases of tinea capitis were detected. the incidence was higher in schools in rural areas (1.9%) than in refugee camps (1.1%) or urban areas (0.4%). al ...19989715641
fungal flora in human skin and skin appendages infections in the region of lódź, poland.in the years 1987-95, 3550 patients with mycotic skin infections were divided into two groups: a group of 2282 (64.3%) subjects with dermatophytosis and a group of 1268 (35.7%) subjects with other fungal infections. among dermatophytes the most common infectious agent was trichophyton mentagrophytes (33%), followed by t. rubrum (30%) and microsporum canis (11%). a total of 17% of all infections were caused by candida sp.19989715642
relapsing tinea capitis by microsporum canis in an adult female renal transplant recipient.scalp ringworm is very uncommon in adults. the occurrence and the atypical clinical course of this unusual dermatophytosis in a female renal transplant recipient are described. furthermore, the prevalence and the clinical features of superficial fungal infection in renal transplant recipients are reviewed. as immunosuppression enhances the risk of antifungal therapy failure, more prolonged treatment and careful follow-up are necessary to obtain complete recovery from any dermatophytosis in renal ...19989730705
[epidemiology of microsporum langeronii tinea capitis in the paris suburban area. results of 2 school and familial surveys].one epidemiologic survey was carried out in two children communities, following detection of several cases of microsporum langeronii tinea capitis.19979740866
a survey of dermatophytosis in animals in madras, india.two hundred and eleven dogs (including strictly house and stray dogs) and 170 cattle in and around the city of madras, india were screened for the presence of dermatophytosis. 106 strains of dermatophytes (89 strains from dogs and 17 strains from bovines) were isolated. 57/106 strains were trichophyton mentagrophytes var. mentagrophytes and 42/106 strains were of the microsporum gypseum complex. 5 strains of t. rubrum and 2 strains of t. simii were also obtained in culture. a predominance of m. ...19979691501
[dermatophytes isolated in our clinics. 5-year-study in zaragoza].this review summarizes the different species of dermatophytes isolates in our laboratory between 1991 and 1995. we describe the clinical forms and establish the distribution over this period of time.19979580210
microsporum canis infection of the penis. 19979582492
[mycetomas caused by microsporum canis. report of one case].we report an eight years old boy presenting with a pyogenic granuloma of the scalp, generalized alopecia, descamative plates in the neck, trunk and limbs and nail involvement. cultures for fungus of all these lesions disclosed microspore canis. the patient was treated with oral griseofulvin, miconazole and topical tolnaftate. five years later and after several incomplete treatments, the patient returns with a fistulous mass of 15 x 8 cm in the dorsal area whose culture revealed microspore canis. ...19979567397
the use of oral terbinafine (lamisil) in children.in an ongoing study of lamisil in children, 21 patients have so far been enrolled and preliminary data are reported in this paper. eighteen have tinea capitis and 1 has tinea corporis. so far, trichophyton tonsurans has been identified in 17 and trichophyton violaceum in 2. lamisil has so far proved to be well tolerated, efficacious and cost-effective in a 2-week course in those children with a trichophyton species. if microsporum canis is isolated, a longer course is probably indicated. lamisil ...19979154402
controversies in medical mycology.questions and controversies involving many aspects of medical mycology have increased in recent years. case histories are described in which fungal infection causes unexpected and atypical problems. molecular techniques of diagnosis need to be used alongside traditional culture methods. increased drug use has led to genuine concerns and differing views regarding the definition and development of resistance by fungi. the use and value of combinational antifungal therapy and the employment of immu ...19979154403
an atp bioluminescence assay applicable to rapid fluconazole susceptibility testing of dermatophytes.an atp bioluminescence assay as a rapid reference method for fluconazole (flcz) susceptibility testing of dermatophytes, as well as yeasts, was developed and evaluated by comparing it with viability, turbidity and fungal protein content-based conventional methods. flcz susceptibility results obtained with strains of candida albicans and dermatophytes by the bioluminescence method in high-resolution medium were well correlated with those obtained by conventional methods currently used in clinical ...19979194036
tinea capitis in adults: misdiagnosis or reappearance?according to the literature, tinea capitis in adults is supposed to be rare; we have recently observed a significant increase in cases.19979031783
lack of efficacy of 6-week treatment with oral terbinafine for tinea capitis due to microsporum canis in children.twenty-two children aged 2 to 9 years with noninflammatory tinea capitis due to microsporum canis were evaluated in an open clinical pilot study run from january 1994 to july 1995. each child was given oral terbinafine according to body weight for 6 weeks. mycologic evaluation was done at the end of treatment and after follow-up periods of 4 and 8 weeks. none of the patients achieved complete mycologic cure by the end of the treatment period. four weeks later complete mycologic cure was establis ...19979050765
survey of dermatophytes isolated from the coats of laboratory animals in italy. 19979051650
in vitro evaluation of antifungal properties of 8.o.4'-neolignans.eighteen racemic 8.o.4'-neolignans with six different substitution patterns in rings a and b, in their ketone and in their erythro and threo alcoholic forms, were evaluated for antifungal activity by the agar dilution method. only the alcohols exhibited a broad spectrum of activities against microsporum canis, microsporum gypseum, tricophyton mentagrophytes, tricophyton rubrum, and epidermophyton floccosum. (+/-)-erythro-3,4-(methylenedioxy) -7-hydroxy-1'-allyl-3',5'-dimethoxy-8.o.4'-neolignan ( ...19979249968
[microsporum infections in hajdú-bihar county].mycotic infections caused by microsporum canis occurred in 237 cases between 1983-1995 in hajdú-bihar county. the disease accumulated seasonally up during the beginning of summer and the end of autumn, in particularly. children and young people had often got microsporiasis. women patients seemed to be more frequent than men. the disease in many cases, appeared on all members of families. a main factor in spreading of pathogen were apparently healthy persian cats. only few cases could be observed ...19979254352
dermatophytomycoses in children in rural kenya: the impact of primary health care.in a survey of 5780 children from 13 schools in rural kisumu district (western kenya) in 1993, a prevalence rate of dermatophytomycoses of 10.1% was found. three-quarters of the affected children suffered from tinea capitis (prevalence rate 7.8%), caused by microsporum audouinii var. langeronii, trichophyton violaceum and microsporum canis. in 1994, a dermatology programme within the primary health care system was started. twelve community health workers (chws), trained in diagnosis and treatmen ...19979260482
[dermatophytoses in the urban environment and the coexistence of man with dogs and cats].there have been submitted to clinical exam in laboratory of dermatophytosis and inquired about possible contact with domestic animals (dogs and cats) 158 patients living in the urban area of fortaleza, that showed lesions suspected of dermatophytosis. this search associated to the obtained data in questionnaires permitted us to identify the frequency of domicile outbreaks. within the 83 people with dermatosis isolated of human infections, prevailed the anthropophilic species over the zoophilic o ...19979265224
purification and characterization of manganese superoxide dismutase from ganoderma microsporum.manganese superoxide dismutase (mn-sod) in the mycelium of ganoderma microsporum was purified to homogeneity by heat treatment at 70 degrees c, ammonium sulfate fractionation, deae-52 anion-exchange chromatography, and sephacryl sh-200 chromatography. the molecular mass of its native form was estimated to be 98 kd by size-exclusion chromatography. this enzyme is tetrameric composed of four subunits of equal size of 25 kd. the pi of this purified mn-sod was located at ph 6.34 and 5.06 by isoelect ...19979285072
itraconazole pulse therapy is effective in the treatment of tinea capitis in children: an open multicentre study.in an open multicentre study we have demonstrated that itraconazole pulse therapy, 5 mg/kg per day, is effective and safe in the management of tinea capitis in 10 children (seven boys, three girls, mean age: 6.6 years, age range 4-11 years). the causative organisms were trichophyton tonsurans (six cases), t. violaceum (two cases), t. soudanense (one case) and microsporum gypseum (one case). each pulse of drug therapy lasted 1 week with 2 weeks off between consecutive pulses. one, two and three p ...19979292075
prevalence and characterization of microsporum canis carriage in cats.in order to determine the prevalence and to characterize the carriage of microsporum canis in cats, different mycological examinations (including a culture obtained by hair brushing and wood's light examination) were performed on 632 animals of different origins. group 1 comprised 467 healthy pet cats belonging to veterinary students. in this group, prevalence of carriage was 2.1%: eight cats were asymptomatic transient carriers and one cat was an asymptomatic infected animal presenting discrete ...19979292421
contact-sensing by hyphae of dermatophytic and saprophytic fungi.contact-sensing or thigmotropism is the directional growth response of cells in relation to topographical guidance cues. thigmotropism is thought to play a major role in the location of infectable sites on plants by phytopathogenic fungi and has recently been shown to be a property of hyphae in the human pathogenic fungus candida albicans. here we show that hyphae of the dermatophytes epidermophyton floccosum, microsporum canis and trichophyton mentagrophytes reorientate their direction of growt ...19979292428
disseminated dermatophytosis caused by microsporum gypseum in two patients with the acquired immunodeficiency syndrome.microsporum gypseum is not a common agent of human dermatophytosis. to the best of our knowledge, this fungus has not been described in human immunodeficiency virus (hiv)-infected patients. we report a tinea corporis infection with atypical presentation caused by m. gypseum in two patients with the acquired immunodeficiency syndrome (aids) studied at the são paulo hospital (são paulo, brazil).19979299752
hair loss in a 5-year-old boy. tinea capitis caused by microsporum gypseum. 19979301597
systemic antifungal treatment of children with terbinafine.at present, griseofulvin is the only licensed drug for oral treatment of dermatophyte infections in children.19979310719
dermatophytes isolated from domestic animals in barcelona, spain.this retrospective study deals with the main samples studied at the mycology diagnostic service of the faculty of veterinary science of barcelona: animals with suspected dermatophytosis. over a ten-year period from 1986 to 1995, 136 dermatophytes were identified from dog and cat cultures submitted for identification and from specimens submitted for mycological examination from a variety of other domestic animals. the most frequent dermatophytes isolated were microsporum canis (55.9%), trichophyt ...19979335154
molecular determination of dermatophyte fungi using the arbitrarily primed polymerase chain reaction.dermatophytes are keratinophilic fungi capable of causing dermatophytosis (commonly known as tinea or ringworm) in humans and animals. previously, we reported the differentiation of the common dermatophytes trichophyton rubrum, t. mentagrophytes and t. tonsurans using a random primer 5'-acccgacctg-3' (opaa11) in the arbitrarily primed polymerase chain reaction (ap-pcr). in the present study, by examining additional dermatophytes including eight microsporum spp., 16 trichophyton species/subspecie ...19979349328
prevalence of undetected tinea capitis in a school survey in spain.from october 1994 to november 1995, a prospective study aiming to detect dermatophytes on the scalp was undertaken in 5000 unselected school children aged between 3 and 16 years (mean age 8.34 years, sd +/- 3.83). thirty-two (0.64%) had dermatophytes in the scalp, 22. (0.44%) had tinea capitis and 10 were asymptomatic scalp carriers. it is important to point out that 33% of the patients with tinea capitis and 60% of the asymptomatic scalp carriers also had ringworm in other body sites. there was ...19979375502
pcr identification of trichophyton mentagrophytes var. interdigitale and t. mentagrophytes var. mentagrophytes dermatophytes with a random primer.dermatophytes are a group of keratinophilic fungi falling within the genera of epidermophyton, microsporum and trichophyton. the genus trichophyton is particularly important and complex; it comprises at least 15 recognised species. in addition, there are several different variants in the species t. mentagrophytes, which occur both in man and animals. the current methods of determining t. mentagrophytes varieties may require several different culture media and time-consuming procedures, as well a ...19979402927
povidone-iodine wash solutions in the prevention of superficial fungal infections; predictive evaluation using the corneofungimetry bioassay.prevention of superficial mycoses remains a stubborn problem. the effect of antiseptics for that purpose is largely unknown. we studied the potential fungitoxic activity of povidone iodine (pvp-i) contained in wash solutions.19979403279
[dermatophytes do not produce sialidase in vitro].sialidase (ec 3.2.1.18) is a pathogenicity factor of many microorganisms, and may also play a role in adhesion of dermatophytes to the epithelia of their hosts by the hydrolytical cleavage of terminal, negatively charged sialic acids of glycoconjugates on the cell surfaces, thus allowing fungal lectins to bind to the subterminal sugars. therefore, 116 strains of seven species of dermatophytes were investigated for sialidase production. two highly sensitive, quantitative sialidase assays were app ...19979417509
a succinylanthranilic acid ester and other bioactive constituents of jolyna laminarioides.methyl 2-[propanamide-2'-methoxycarbonyl] benzoate, fucosterol, trans-phytol and p-formylphenol were isolated for the first time from a methanolic extract of jolyna laminarioides. methyl 2-[propanamide-2'-methoxycarbonyl]-benzoate exhibited chymotrypsin inhibitory activity and also found to be active against escherichia coli and shigella boydii. fucosterol exhibited antifungal activity against curvularia lunata, stachybotrys atra and microsporum canis.19979423291
[a large plaque with an erythematous-desquamative edge in a farmer]. 19979424671
alteration in protein kinase(s) level affects the phospholipid content in m. gypseum with modulated levels of calcium/cyclic amp.protein kinase(s) have been identified for the first time in microsporum gypseum. it phosphorylated exogenous protein acceptors preferentially histone iis and casein and are mainly localized in the cytosolic fraction of m. gypseum. alterations in protein kinase activity was observed in calcium/aminophylline and atropine (camp modulators) grown cells which is due to the modulation in the ca2+/camp levels. alteration in the protein kinase(s) activity finally affected the total phospholipid content ...19979450642
some aspects of dermatophytoses seen at university hospital in florianópolis, santa catarina, brazil.dematophytoses comprise mycoses which are very frequently diagnosed in the routine of clinical laboratories of florianópolis, like any other brazilian cities. however, no clinical or epidemiological studies data have been published for that city so far. to partially clarify these questions, we carried out a study on this subject on patients who sought the mycology services of hospital of federal university of santa catarina, from january 1995 to november 1996. the most prevalent dermatophyte was ...19979460252
wood's light in microsporum canis positive patients.in 64 patients with culturally proven microsporum canis infections, wood's light examination was performed. in 30 patients (47%) the characteristic fluorescence correlated with the cultural findings, whereas in the remaining 34 patients (53%), microsporum canis was isolated, although wood's light examination was negative. of the 30 positive and 34 negative cases eight patients of each group had been pre-treated. from the results presented, wood's light examination has a poor sensitivity in cases ...19979470413
extracellular enzyme activities of dermatophytes and yeast isolates on solid media.a total of 123 isolates of 14 species of dermatophytes and yeasts were screened for the activity of five extracellular enzymes including elastase, keratinase, protease (gelatinase), lipase and phospholipase, by using solid media. the optimal production and activity of each enzyme was determined with regard to different ph and temperatures. keratinase activity was high with all the tested fungi with exception of malassezia furfur. protease (gelatinase) was produced only by dermatophytes. elastase ...19979470414
dermatophytes isolated from asymptomatic stray cats.most human cases of dermatophytosis diagnosed in siena, italy, in the last 5 years have been caused by two zoophilic species: microsporum canis and trichophyton mentagrophytes. since many patients had a history of contact with apparently healthy stray cats, we examined the fur of 173 stray cats for dermatophytes. the cats were captured in different parts of siena and none of them had mycotic lesions. microsporum canis was isolated in 82 cats, trichophyton mentagrophytes in three and microsporum ...19979470415
isolation of microsporum nanum from a patient with tinea corporis in madras, india.microsporum nanum was isolated from a case of tinea corporis in a 16-year-old boy. this is the first recorded case of human ringworm infection caused by m. nanum in india.19979476494
tinea capitis in children in the district of cagliari, italy.between 1986 and 1995, 4104 children were observed in the clinic of dermatology in cagliari, italy. three hundred and thirty-six children (8.2%), 188 boys and 148 girls, aged 1 month to 13 years, were affected by tinea capitis. microsporum canis was detected in 278 cases (82.7%) and trichophyton mentagrophytes in 58 cases (17.3%). systemic treatment with 20-25 mg kg-1 day-1 griseofulvin led to complete recovery in 30-40 days. none of the patients relapsed. the epidemiology of the infection was a ...19979476495
in vitro interactions between histoplasma capsulatum var. duboisii and other fungi.histoplasma capsulatum var. duboisii has only recently been shown to occur naturally in soil admixed with bat guano in a bat cave. we report our observations on the in vitro interaction of histoplasma capsulatum var. duboisii with other fungi recovered from the same habitat or other sources by employing co-culture technique and by investigating antibiosis between h. capsulatum var. duboisii and other fungi. the range of interactions varied from total overgrowth of histoplasma by aspergillus fumi ...19979476515
itraconazole susceptibility of feline isolates of microsporum canis.the in vitro activity of itraconazole against microsporum canis was evaluated with 38 feline isolates. based on the observed minimum inhibitory concentrations it can be concluded that the drug could be effective in the therapy of cats affected by m. canis ringworm.19979476516
soil dermatophytes in madras, india, in relation to human ringworm.a total of 269 soil samples collected from different habitats in madras, india, were screened for the presence of dermatophytes by the hair-baiting technique. three strains of trichophyton mentagrophytes and 16 strains of microsporum gypseum complex were isolated. these strains were subjected to the mating experiment. 2/3 soil isolates of trichophyton mentagrophytes belonged to arthroderma vanbreuseghemii (+) mating type, and 1/3 was arthroderma vanbreuseghemii (-) mating type. similarly 6/70 cl ...19979476517
prevalence and aetiology of dermatophytoses in isfahan, iran.in this study the prevalence and causative agents of dermatophytoses in isfahan, a large province of iran, were determined. of 16,578 clinically suspected cases 13.3% were affected with dermatophytoses. lesions of tinea capitis were the most prevalent clinical type of dermatophytoses (54.1%), followed by tinea corporis (23.8%) and tinea pedis (8.9%). trichophyton verrucosum was the most frequent causative agent (32.8%), followed by epidermophyton floccosum (17.6%), t. mentagrophytes (16.2%) and ...19979476518
[synthesis and antifungal activity of 1-(1h-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted-2-propanols].twenty-three 1-(1h-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted-2-propanols were synthesized and evaluated for antifungal activities in vitro. the synthetic methods of the intermediates are also reported. the compounds belong to two kinds: sulfones and sulfides. all of the compounds are new. the results of preliminary antifungal test showed that most of the sulfide derivatives exhibited potent activities against six kinds of common pathogenic fungi such as microsporum lanosum, crypt ...199711596195
in vitro evaluation of inhibitory nature of extracts of 18-plant species of chhindwara against 3-keratinophilic fungi.effect of extract of 18 plant species, viz., acorus calamus, adhatoda vasica, amomum subulatum, andrographis paniculata, boerhaavia diffusa, cassia occidentalis, centella asiatica, cymbopogon citratus, hemidesmus indicus, hyptis suaveolens, malvestrum sp., passiflora edulis, pergularia daemia, peristrophe bicalyculata, shuteria hirsuta, solanum nigrum, tecoma stans, and verbascum chinense on the growth of microsporum gypseum, chrysosporium tropicum and trichophyton terrestre was evaluated and di ...199710386016
[clinical and experimental studies on composite divitriol infusion in treating tinea manum].to investigate the effect of composite divitriol infusion (cdi) in treating tinea manum and studying its antimycotic action.19979863080
[etiologic and epidemiologic study of dermatomycoses in navarra (spain)].we review the etiology of the dermatophytosis in navarra (spain) over a 5-year period and it is compared with previous studies. we have isolated 312 strains of dermatophyte fungi in 285 patients (188 men and 97 women). trichophyton rubrum was the most frequently isolated species (58.6%) followed by trichophyton mentagrophytes (26.2%) and microsporum canis (10.5%). concerning the location of the lesions, tinea pedis was the clinical pattern found in the greatest number of patients, followed by ti ...199716854174
clinical and epidemiological study in an aids patient with microsporum gypseum infection.a 37 years old homosexual male with aids was diagnosed as having tinea cruris and tinea corporis. the patient was a garden designer and therefore he used to handle soil very often. microsporum gypseum was identified on cultures from skin-scrapings and biopsy material taken from different cutaneous lesion. the same species was isolated from samples of soil the patient used to work with. the clinical history of the patient and its epidemiological aspects were deeply studied by the authors. we stre ...199715538824
a survey of dermatophytosis in animals in madras, india.two hundred and eleven dogs (including strictly house and stray dogs) and 170 cattle in and around the city of madras, india were screened for the presence of dermatophytosis. 106 strains of dermatophytes (89 strains from dogs and 17 strains from bovines) were isolated. 57/106 strains were trichophyton mentagrophytes var. mentagrophytes and 42/106 strains were of the microsporum gypseum complex. 5 strains of t. rubrum and 2 strains of t. simii were also obtained in culture. a predominance of m. ...199716284812
[enzymatic activities of microsporum canis and microsporum gypseum strains.].the presence of 11 enzymatic activities, detected by qualitative methods, and 19 enzymes, semi-quantitatively detected by api zym system, in strains belonging to microsporum canis and microsporum gypseum has been studied. no pronounced differences were noted between microsporum canis and microsporum gypseum, although microsporum gypseum presented in some cases more intense enzymatic activities than microsporum canis.199717655387
keratinolytic fungi in sewage sludge.sewage sludge from the upper silesia region of poland were surveyed for keratinolytic fungi. out of 100 petri dishes examined, 89 were positive for these micro-organisms. altogether, 185 fungal appearances belonging to 10 species were observed. trichophyton terrestre with its teleomorph arthroderma quadrifidum, t. ajelloi with a. uncinatum, microsporum gypseum with arthroderma sp., and chrysosporium keratinophilum with aphanoascus keratinophilus prevailed in the sludges. the sewage treatment tec ...199620882456
isolation of fungi from soil using the keratin-baiting technique.of 236 soil samples baited with wool, some 71.2% (168) produced fungal growth. gliocladium (25.0%), paecilomyces (14.8%), trichophyton (11.9%) species were the most prevalent in soil moistened with sterile distilled water (sdw) containing antibiotics. on the other hand, in soil moistened with sdw only, trichophyton (32.6%), paecilomyces (27.5%), diheterospora (16.5%), gliocladium (13.6%) and fusarium (13.1%) species were more common. of the known potential pathogens, the paecilomyces and fusariu ...199620882458
clinicomicrobiological aspects of tinea cruris in madras.a total of 242 patients with clinically diagnosed tinea cruris were screened and 181 (74.7 %) were found to be positive in culture for dermatophytes. 93.9% of infections were caused by trichophyton spp., of which 58.4% were trichophyton rubrum, 5.5% were epidermophyton floccosum, 3.8% were trichophyton tonsurans and we had a single isolate of microsporum gypseum complex. incidence of tinea cruris was higher in males (95.6%) than in females (4.4%). 45% of the cases were recurrent and 38% of cases ...199620948056
[scanning electron microscope sudy of the morphology of fungi isolated from patients at the aristide la dantec hospital in dakar, senegal].in order to improve the identification of fungi usually isolated among some patients at dantec hospital, a study by scanning electron microscopy has been carried out. it deals with four species of yeasts (candida albicans, candida parapsilosis, rhodotorula rubra sacharomyces cerevisiae) six species of dermatophytes (trichophyton rubrum, trichophyton soudanense, trichophyton interdigitale, microsporum canis, trichophyton violaceum, microsporum audouinii); two species of mildew, (aspergullus flavu ...19969827085
[in vitro antifungal activity of omoconazole nitrate, a novel imidazone antimycotic drug, against clinical isolates from patients with cutaneous mycosis].in vitro antifungal activities of omoconazole nitrate (omz), a novel antifungal imidazole antimycotic drug, are examined against clinical isolates obtained from patients with cutaneous mycosis and its activity was compared with that of bifonazole (bfz). the clinical isolates tested were 70 of dermatophytes including trichophyton rubrum (47 isolates), t. mentagrophytes (22 isolates), microsporum gypseum (1 isolate), and 27 isolates of candida albicans. mic values of omz to dermatophytes distribut ...19969053537
outbreak of tinea capitis caused by microsporum ferrugineum in thailand.there was an outbreak of tinea capitis at the pak-kred home for mentally and physically handicapped babies, bangkok, thailand in 1993. one hundred and thirty-eight cases were diagnosed as tinea capitis based on clinical signs and positive laboratory investigations. the results of wood's light examination, koh preparation and fungal culture were positive in 89.9, 75.9 and 27.4% respectively. the non-inflammatory form had a higher rate of positive koh and culture than in the inflammatory form. mic ...19969066157
unusual treatment of severe cutaneous lupus. 19968899228
fungal flora of the hair coat of stray cats in iran.the fungal flora of the hair coat of 100 stray cats in different districts of the city of isfahan, iran, were examined. saprophytic fungi were isolated from all cats. penicillium, aspergillus, alternaria, mucor and cladosporium spp. were the most frequently isolated saprophytes. microsporum canis was isolated from all kittens with clinical signs of dermatophytosis. in other cases, m. canis was isolated only from 22 of the 96 cats. no significant differences in sex, hair length, and fungal flora ...19968909038
unusual microsporum canis infections in adult hiv patients.tinea capitis in men, even if infected with hiv, is infrequent. microsporum species nail infections are extremely rare. in most cases microsporum canis infection is usually easy to treat with antifungal agents. we describe two hiv-infected men with an unusual m. canis infection. both patients had tinea capitis, presenting as alopecia in one and scaling of the scalp in the other. one patient also had tinea unguium caused by m. canis. ketoconazole was ineffective in both patients; terbinafine was ...19968912591
diagnostic results in animal dermatophytoses.superficial mycoses caused by dermatophytes, as well as asymptomatic carriership of dermatophytes, have a high prevalence among domestic animals and pets. we examined 606 clinical specimens from skin lesions of animals with a significant tendency towards superficial mycosis due to their clinical features. samples were obtained from horses, dogs, cats, small rodents, birds, and rabbits. the specimens were examined by microscopic and cultural techniques. microscopically, there was no significant d ...19968976618
tinea capitis in south-east london--a new pattern of infection with public health implications.recent observations on tinea capitis cases in london suggest that there has been a change in the pattern of infection with a recent and significant rise in the incidence of infections due to anthropophilic fungi. the purpose of this study was to investigate the prevalence and identity of tinea capitis in schools in south-east london and factors which might affect the spread of infection. this was achieved by carrying out a survey of all children, with parental consent for scalp examination, in 1 ...19968977718
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