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normal range of mean platelet volume in healthy subjects: insight from a large epidemiologic study.aim: mean platelet volume (mpv) in the healthy population has not been studied before. therefore, the aim of the study was to measure mpv in normal subjects in a large cohort of turkish adults. methods: a total of 2298 subjects with a mean age of 50 (age range 18 to 92) were interviewed. subjects who had smoking habit, diabetes, hypertension, coronary artery disease, dyslipidemia, chronic obstructive pulmonary disease, cancer, chronic use of any drugs including antiplatelets, heavy drinkers, met ...201121620440
intravenous calcium infusion as a novel preventive therapy of ovarian hyperstimulation syndrome for patients with polycystic ovarian syndrome.objective: to evaluate the effectiveness of iv calcium infusion on prevention of ovarian hyperstimulation syndrome (ohss) in patients with polycystic ovary syndrome undergoing assisted reproductive techniques cycles. design: a retrospective comparative study. setting: assisted reproduction techniques centre in turkey. patient(s): four hundred fifty-five women with high risk for ohss. intervention(s): the patients in group i (n = 84) were administered iv calcium gluconate for prevention of ohss, ...201121621772
oxygen supply from the bird's eye perspective: globin e is a respiratory protein in the chicken retina.the visual process in the vertebrate eye requires high amounts of metabolic energy and thus oxygen. oxygen supply of the avian retina is a challenging task because birds have large eyes, thick retinae and high metabolic rates, but neither deep retinal nor superficial capillaries. respiratory proteins like myoglobin may enhance oxygen supply to certain tissues and thus the mammalian retina harbors high amounts of neuroglobin. globin e (gbe) was recently identified as an eye-specific globin of chi ...201121622558
brevibacillus aydinogluensis sp. nov., a moderately thermophilic bacterium isolated from karakoc hot spring in turkey.two gram-positive, moderately thermophilic, endospore-forming, rod-shaped, motile bacteria were isolated from karakoc hot spring in the provinces of izmir, turkey and were characterized in order to determine their phylogenetic positions. these strains were designated as pdf25t and pdf30. 16s rrna gene sequence analysis revealed that the two strains belonged to the genus brevibacillus; strain pdf25t showed highest sequence similarity to strain pdf30 (99.4 %), brevibacillus thermoruber dsm 7064t ( ...201121622837
present and future directions of translational research on aflatoxin and hepatocellular carcinoma. a review.the aflatoxins were discovered in toxic peanut meal causing "turkey x" disease, which killed large numbers of turkey poults, ducklings and chicks in the uk in the early 1960s. extracts of toxic feed induced the symptoms in experimental animals, and purified metabolites with properties identical to aflatoxins b(1) and g(1) (afb(1) and afg(1)) were isolated from aspergillus flavus cultures. structure elucidation of aflatoxin b(1) was accomplished and confirmed by total synthesis in 1963. afb(1) is ...201121623489
cognitive behavioral therapy-based brief intervention for volatile substance misusers during adolescence: a follow-up study.of 62 males admitted for treatment in turkey in 2008 with a diagnosis of volatile substance misuse (vsm) dependency, half were randomly allocated to receive a cognitive behavioral therapy (cbt)-based brief intervention and an education program and half participated only in the education program. one year after treatment, 38.2% of the experimental group and 58.1% of the control group had continued vsm during the last three months. this statistically significant difference indicates that cbt-based ...201121609157
association of the ptpn22 gene polymorphism with autoantibody positivity in turkish rheumatoid arthritis patients.the ptpn22 c1858t gene polymorphism has been recently reported to be associated with rheumatoid arthritis (ra) in european and north american ancestry. in contrast, the frequency of ptpn22 c1858t polymorphism is extremely rare in asian and african populations. as the genetic heterogeneity between populations is clearly present in ra, we wanted to investigate whether the ptpn22 c1858t polymorphism is associated with ra in turkey and with autoantibody positivity. a total of 323 ra patients and 426 ...201121506938
statin use is associated with lower inflammation and erythropoietin responsiveness index in hemodialysis patients.patients with end-stage renal disease are prone to inflammation and inflammation is related to erythropoietin-stimulating agent hyporesponsiveness and mortality in this population. statins have been demonstrated to reduce cardiovascular mortality in selected populations of end-stage renal disease patients. these drugs have pleiotrophic effects such as anti-inflammation. in this retrospective analysis, we determined whether the use of statins improves inflammation and inflammation-related anemia ...201121507195
high mobility group box protein-1 (hmgb-1) as a new diagnostic marker in patients with acute appendicitis.:201121507210
narrowing of airway caused by ingestion of methyl ethyl ketone peroxide.although ingestion of methyl ethyl ketone peroxide (mekp) is rare, it carries a high risk of morbidity and mortality. this paper reports the first such case from turkey in which a 70-year-old man unintentionally ingested mekp in his kitchen. the patient was brought into the emergency department (ed) within 1 hour of ingestion, with the symptoms of sore throat, shortness of breath, nausea and vomiting. visual examination of the oropharynx revealed minor burns and uvular edema. a laryngoscope exam ...201121508070
serotypes of streptococcus pneumoniae isolates from children with invasive pneumococcal disease in turkey: baseline evaluation of the introduction of the pneumococcal conjugate vaccine nationwide.before use of the pneumococcal conjugate vaccine pcv7 became widespread in turkey, 202 invasive pneumococcus isolates were analyzed. the most common serotypes were 19f and 6b. in children ≤2 years of age, the potential coverage rate of pcv7 was 69.5%. the most frequent non-pcv7 serotypes were 19a, 3, 1, 6a, and 8.201121508171
a gis-based decision support system for determining the shortest and safest route to forest fires: a case study in mediterranean region of turkey.the ability of firefighting vehicles and staff to reach a fire area as quickly as possible is critical in fighting against forest fires. in this study, a geographical information system-based decision support system was developed to assist fire managers in determining the fastest and the safest or more reliable access routes from firefighting headquarters to fire areas. the decision support system was tested in the kahramanmaras forestry regional directoratein the mediterranean region of turkey. ...201121509512
immunity against diphtheria among children and adults in izmir, turkey.the aim of this study was to evaluate diphtheria immunity in a sample of the turkish population having high childhood immunization coverage, including a booster dose of diphtheria toxoid at 12-15 years of age. a total of 599 persons aged 1-70 years were selected with cluster sampling. the information on socio-demographic characteristics, vaccination status and diphtheria history was gathered for each participant. diphtheria antitoxin levels were measured qualitatively by using micro-enzyme immun ...201121510994
the effects of an insertion in the 5'utr of the amcase on gene expression and pulmonary functions.background: studies regarding the physiological role of acidic mammalian chitinase (amcase) and the effects of its genetic variants on asthma have produced conflicting results. objectives: we aimed to determine the genetic variants in the amcase gene that could regulate the gene expression and thus influence disease severity. methods: genetic variants of the amcase gene were determined by sequencing of asthmatics and healthy controls in up to -1 kb in the promoter region and exon 1 and 2. in an ...201121511453
trpc6 gene variants in turkish children with steroid-resistant nephrotic syndrome.background: in steroid-resistant nephrotic syndrome (srns), a considerable number of patient progress to end-stage renal disease (esrd), despite aggressive therapy. the latest advance in familial focal segmental glomerulosclerosis (fsgs) has been the discovery of a mutant form of canonical transient receptor potential channel 6 (trpc6) leading to fsgs through unclear mechanisms. the aim of this study is to screen for trpc6 mutations in familial and sporadic srns patients. methods: twenty-five ch ...201121511817
anti-oxidative and anti-genotoxic effects of methanolic extract of mentha pulegium on human lympocyte culture.in the present work, methanolic extract of mentha pulegium from erzurum, turkey, was used in order to report the results of anti-oxidant capacity, anti-oxidant activity and anti-genotoxic effects. the total antioxidant capacity and total phenolic content were measured by using cuprac, abts and folin-ciocalteu colorimetric methods. the total phenolic content was higher than the total antioxidant capacity (for the results of both the cuprac and abts methods) of methanolic extract of m pulegium (me ...201121511894
identification of potential serodiagnostic and subunit vaccine antigens by antibody profiling of toxoplasmosis cases in turkey.toxoplasmosis, caused by infection of the protozoan parasite toxoplamsa gondii, is associated with mild disease in healthy individuals, and may develop encephalitis, neurologic disorders and other organ diseases in individuals with depressed immunity. women who develop acute toxoplasmosis during pregnancy are at risk of transmitting the infection to the fetus which may lead to fetal damage. a diagnosis is usually confirmed by measuring igg, or igm where it is important to determine the onset of ...201121512035
the health status of first- and second-generation turkish immigrants in germany.objectives: since previous research on immigrants' health status is rare, this study focuses on turkish immigrants currently living in germany and evaluates their subjective health status using relatively new data from the generations and gender survey (2005/2006). methods: the cross-sectional study includes around 10,000 german natives and 4,000 turkish immigrants. logistic regression models are estimated to compare the health of first- and second-generation turkish immigrants with that of germ ...201121512755
investigation of the sexual behavior of pregnant women residing in squatter neighborhoods in southwestern turkey: a qualitative study.the authors designed this study in order to understand changes in sexual behavior during pregnancy. the sample comprised 26 healthy women who were in at least their 37th week of pregnancy. the authors collected data through in-depth individual interviews. participants reported the following most common reasons for ceasing sexual intercourse in the final stages of pregnancy: (a) physical discomfort during sex, (b) belief that it could be physically harmful to the fetus, (c) belief that it is sinf ...201121512939
loneliness in elderly individuals, level of dependence in activities of daily living (adl) and influential factors.this study has been carried out to investigate the level of loneliness, determine the level of dependence in the adl and influential factors in the elderly people. this descriptive, cross-sectional study was conducted in 5 family healthcare centers (fhc) located in central erzincan, turkey between march and june 2010. the data of the research was collected using a questionnaire that determined the descriptive and ucla loneliness scale (ucla-ls). mean score of the ucla-ls was determined as 51.59± ...201121514680
organochlorine pesticide and polychlorinated biphenyls levels in fish and mussel in van region, turkey.forty-seven fish (24 endemic alburnus tarichi, güldenstädt, 1814; 8 capoeta capoeta, guldenstaedt, 1772; 15 mirror carp cyprinus carpio, l., 1758) and 13 mussel (unio stevenianus, krynicki, 1837) samples, with 10 specimens per sample, were collected from van lake, turkey, and rivers flowing into it. gamma-hch was detected in 21 alburnus tarichi samples (56.57 ng/g ± 22.18 ng/g) and in two capoeta capoeta samples (27.6 ng/g and 36.45 ng/g). beta-hch was detected in 8 alburnus tarichi samples (24. ...201121516453
do turkish nursing and midwifery students teach breast self-examination to their relatives?aim: to describe health beliefs and breast self-examination (bse) practice of turkish female nursing and midwifery students and extent of teaching the screening method to their mothers, sisters and relatives. design: in this definition survey, data were obtained from 113 nursing and midwifery students (n = 113) in third and fourth class and their mothers, sisters and other relatives in turkey. methods: data were collected using a personal data form, a knowledge evaluation form for bse (maurer 19 ...201121517241
effects of training about skin cancer on farmers' knowledge level and attitudes.background: skin cancer is one of the most common types of cancer. as farmers stay under sun for a long time and handle many different chemicals, they are at risk. this study was carried out to examine the effects of training for protection on their knowledge level and attitudes. method: the subjects were 194 farmers living in a village in marmara region which most benefits from the sun in turkey. no sampling was performed. data were collected before and after six months of training through a pe ...201121517242
turkish validity and reliability of a pediatric quality of life cancer module for children aged 8-12 and parents.this descriptive study was conducted to determine the validity and reliability in turkey of the pediatric quality of life inventory cancer module (pedsql 3.0) for children aged 8-12 in the hematology-oncology polyclinics of two university hospitals in istanbul during the period 2006-2007. the data collection instruments were the pediatric quality of life inventory (pedsql 4.0), the pediatric quality of life inventory cancer module (pedsql 3.0) and a socio-demographic questionnaire, applied for 1 ...201121517244
cognition of breast cancer among gestational age turkish women: a cross-sectional study.the aim of the study is to describe the cognition of breast cancer with respect to knowledge, beliefs, attitudes and behavior in a group of gestational age turkish women. a questionnaire survey was therefore performed on 201 randomly selected women registered to the health database in aydin. in age, marital status, and occupation were found to significantly impact on breast self-examination (bse) performance, which should still be considered as an important tool for early diagnosis, although it ...201121517271
specialist physicians should be aware of the national cancer control and screening program: a report from medical oncologists in turkey. 201121517283
reliability and validity of turkish version of attitudes toward old people scale.aims and objectives.  to assess the reliability and validity of a turkish version of kogan's attitudes toward older people scale. background.  to explore nursing students' attitudes towards older people, standardised, well-tested instruments are needed. kogan's attitudes toward older people is a comprehensive instrument for assessment of attitudes toward older adults and has been validated in several languages. however, a validated turkish version has not been available until now. design.  the s ...201121518058
serial urological interventions including circumcision in a hemophilic child with inhibitors.hemophilia patients sometimes need careful treatment of urgent serious bleedings and management of some surgeries. development of inhibitor has some impact on the management of these situations. here a case of patient of hemophilia a is presented in whom urological surgery resulted in inhibitor development and a second operation with bypass agent.201121519231
evaluation of night-time pain characteristics and quality of sleep in postoperative turkish orthopedic patients.this descriptive, correlational study was conducted to determine orthopedic patients' night-time pain characteristics, their quality of sleep and the contributing factors to poor sleep experiences, and the relationship between pain and sleep. data were collected by using the mcgill pain questionnaire-sf (mpq-sf) and pittsburgh sleep quality index (psqi) on the second postoperative day. data were analyzed using the spss version 10.0 for windows. mean age of the 75 patients was 49.55 ± 21.10 years ...201121521827
thyroid tuberculosis in southeastern turkey: is this the resurgence of a stubborn disease?background: while tuberculosis (tb) has been found in many parts of the body, involvement of the thyroid gland is rare. in this study we describe the clinicopathological characteristics of seven patients with primary thyroid tuberculosis (ttb). methods: this report is a retrospective case study of seven patients with thyroid tuberculosis who were treated surgically in our clinic between 2004 and 2010. data collected from the cases included age, sex, clinical presentation, concurrent medical illn ...201121523497
prevalence of specific igg-antibodies against toxoplasma gondii in domestic turkeys determined by kinetic elisa based on recombinant gra7 and gra8.the protozoan parasite toxoplasma (t.) gondii is one of the most common zoonotic infectious agents worldwide. besides its sexual reproduction in cats, t. gondii can also infect a wide spectrum of other warm-blooded animals. these include animals used for human consumption such as pigs or chickens. nevertheless, the role of turkeys for the epidemiology of t. gondii infections has not been studied thoroughly. we have established a kinetic elisa (kela) for the detection of t. gondii-specific igg an ...201121524853
testing the psychosis continuum: differential impact of genetic and nongenetic risk factors and comorbid psychopathology across the entire spectrum of psychosis.a growing number of studies demonstrate high rates of subthreshold psychotic experiences, but there is considerable heterogeneity in rates due to study cohort and design factors, obscuring how prevalent psychotic experiences may or may not relate to rare psychotic disorders. in a representative general population sample (n = 4011) in izmir, turkey, the full spectrum of expression of psychosis was categorized across 5 groups representing (1) absence of psychosis, (2) subclinical psychotic experie ...201121525167
nosocomial infections and risk factors in the intensive care unit of a teaching and research hospital: a prospecive cohort study.background: to evaluate the incidence, risk factors and etiology of nosocomial infections (nis) in the intensive care unit (icu) of our hospital in order to improve our infection control policies.<br /> material/methods: a 1-year prospective cohort study of nosocomial infection (ni) surveillance was conducted in our icu in 2008.<br /> results: out of 1134 patients hospitalized in the icu for a period of 6257 days, 115 patients acquired a total of 135 nis distributed as follows: 36.3% bacteremia, ...201121525819
each under his own vine and fig tree. 201121525940
late byzantine mineral soda high alumina glasses from asia minor: a new primary glass production group.the chemical characterisation of archaeological glass allows the discrimination between different glass groups and the identification of raw materials and technological traditions of their production. several lines of evidence point towards the large-scale production of first millennium ce glass in a limited number of glass making factories from a mixture of egyptian mineral soda and a locally available silica source. fundamental changes in the manufacturing processes occurred from the eight/nin ...201121526144
tradeoff between biomass and flavonoid accumulation in white clover reflects contrasting plant strategies.an outdoor study was conducted to examine relationships between plant productivity and stress-protective phenolic plant metabolites. twenty-two populations of the pasture legume white clover were grown for 4½ months during spring and summer in palmerston north, new zealand. the major phenolic compounds identified and quantified by hplc analysis were glycosides of the flavonoids quercetin and kaempferol. multivariate analysis revealed a trade-off between flavonoid accumulation and plant productiv ...201121526153
survey of the opinions on the occupational health system in turkey expressed by patients of the istanbul hospital of occupational diseases.to examine the opinion of patients of an occupational diseases hospital on the quality of provision of occupational medicine services in turkey.201121526384
student teachers' observations of unfavorable teacher behaviors exhibited in classrooms.the aim of this study was to identify male and female teachers' misbehaviors in classrooms and determine the variance of those misbehaviors in schools in different socioeconomic areas. the study was conducted in 24 primary schools in erzurum province with a total of 210 classroom teachers. data were obtained through observations made by 210 student teachers. the data collected were analysed through descriptive analyses by the researcher. 661 misbehaviors were observed and classified into six dif ...201121526590
turkish children's bender-gestalt test performance: differences in public and private school children.the present study was undertaken to provide data on the bender-gestalt test for children aged 5 to 11 in turkey. although it is well documented that sociocultural factors are important in cognitive evaluations, the effects of type of school and differing educational opportunities provided by these schools on the bender-gestalt test have not been previously investigated. the aim of the present study was to investigate the effect of age, sex, and school type on bender-gestalt performance. the test ...201121526603
follow-up sonographic results for graf type 2a hips: association with risk factors for developmental dysplasia of the hip and instability.objectives- the purpose of the study was to evaluate the association of sonographic worsening in type 2a hips with risk factors of developmental dysplasia of the hip, stability of the hip, and initial sonographic findings. methods- among infants who were referred for hip sonography between 2007 and 2009, 3450 were included in this study. sonographic examinations were performed by combining the static graf technique and the dynamic harcke technique. the rate of sonographic worsening in type 2a hi ...201121527616
unusual histopathological findings in appendectomy specimens: a retrospective analysis and literature review.to document unusual findings in appendectomy specimens.201121528073
evaluation of children with nutritional rickets.to evaluate the clinical findings, risk factors, therapy and outcome in 946 children with nutritional rickets.201121528813
effects of lower extremity revascularization on the endothelial functions measured with noninvasive brachial artery flow-mediated dilatation.background: endothelial function is best measured with the noninvasive brachial artery flow-mediated dilatation (fmd) method. peripheral arterial diseases and systemic cardiovascular diseases have fmd-lowering effect. the effects of lower extremity ischemia are associated with muscle inflammation and claudication, which may further lead to arterial stress. our aim in this study was to investigate the effects of peripheral arterial revascularization on the endothelial functions through noninvasiv ...201121530156
pressurized liquid extraction of phenolic compounds from anatolia propolis and their radical scavenging capacities.propolis samples from important honey producing locations of anatolia namely; bingol (bg), rize (rz), tekirdag (tk) and van (vn), were evaluated for their antiradical capacities, total phenolic contents and individual phenolic compounds which was recovered by means of pressurized liquid extraction (ple). several extraction parameters of ple such as; temperature, pressure, solvent type, extraction time and cell size were investigated for their effects on the extraction performances. the results s ...201121530603
hepatic granulomas: a clinicopathologic analysis of 86 cases.the aim of this study was to determine the prevalence and histopathological characteristics of hepatic granulomas. all records of liver biopsies/resections evaluated in our pathology department between 2002 and 2009 were retrospectively reviewed. specimens with hepatic granulomas were reexamined by a designated pathologist. type and localization of granulomas, size of granulomas and epithelioid histiocytes, and the morphological findings of surrounding liver tissue were recorded in an attempt to ...201121531083
basilic vein transposition fistulas versus prosthetic bridge grafts in patients with end-stage renal failure.background: basilic vein transposition fistulas (bvtfs) and prosthetic bridge grafts (pbgs) provide good vascular access for hemodialysis. to evaluate the patency and complication rates after arteriovenous fistula formation, a concurrent series of patients was reviewed. methods: between september 2003 and september 2009, 147 hemodialysis access procedures were performed in 147 consecutive patients at van research and training hospital and yuzuncu yil university hospital, van, turkey. all access ...201121531117
determination of antimicrobial susceptibility patterns and inducible clindamycin resistance in staphylococcus aureus strains recovered from southeastern turkey.background: in this study, we determined the susceptibility patterns of staphylococcus aureus strains to various antimicrobials and prevalence of inducible clindamycin resistance (icr) in these isolates. methods: two hundred one s aureus strains, isolated from various clinical samples, were included in the study. antibiotic susceptibilities were studied by disc diffusion method on the basis of the guidelines by the clinical and laboratory standards institute. the disc diffusion induction test (d ...201121531354
il18 polymorphism is associated with behcet's disease but not lupus in patients from turkey. 201121532063
c825t polymorphism of the g-protein β3 subunit and its association with essential hypertension in uzbek males.we investigated the association between the c825t polymorphism of the g-protein β3 subunit (gnb3) gene with essential hypertension (eh) and cardiovascular remodeling markers in uzbek males.201121532295
[heart health policies of the european union and turkey.]cardiovascular diseases cause 4.3 and 2 million deaths in europe and the european union countries each year, respectively, ischemic heart diseases and stroke being the leading causes of death. this review aims to present a brief appraisal of heart health policies of the european union and turkey.201121532305
neurological symptoms and signs in behçet disease: a western turkey experience.to assess the clinical patterns of neurologic involvement and the frequencies and characteristics of different types of headaches in patients with behçet disease.201121532383
il-12rβ1 deficiency in two of fifty children with severe tuberculosis from iran, morocco, and turkey.in the last decade, autosomal recessive il-12rβ1 deficiency has been diagnosed in four children with severe tuberculosis from three unrelated families from morocco, spain, and turkey, providing proof-of-principle that tuberculosis in otherwise healthy children may result from single-gene inborn errors of immunity. we aimed to estimate the fraction of children developing severe tuberculosis due to il-12rβ1 deficiency in areas endemic for tuberculosis and where parental consanguinity is common.201121533230
nonspecific low back pain in a group of young adult men.low back pain (lbp) is a common symptom that causes enormous social, psychological, and economical problems. we studied lbp occurrence in a group of young adults referred to an army hospital for a planned health check and evaluated possible causative factors by prospective questionnaires. material and201121534192
remembering ihsan doğramaci. 201121534332
the status of women and of maternal and perinatal health in turkey.turkey has improved the status of women and the maternal and perinatal health statistics in the last decades. however, discrepancies between urban-rural and east-other regions continue, with some improvements. the education of girls is promoted and maternal age at marriage and at first delivery has increased. birth control measures are increasingly used. fertility rates decreased to 2.16 children per fertile woman. antenatal care standards have improved, and achievement of deliveries by health c ...201121534333
pediatric pulmonology in a developing country: our focus.this study was designed to determine the profile of our pediatric pulmonology unit in turkey, a developing country, by investigating the patients admitted to our unit for the first time. our objectives were: to determine the profile of patients admitted for the first time, to compare their initial diagnoses before referral to our hospital with the diagnoses determined in our unit, to determine the definitive diagnoses for patients requiring advanced intervention with invasive diagnostic methods, ...201121534334
a novel mutation in the dguok gene in a turkish newborn with mitochondrial depletion syndrome.deoxyguanosine kinase (dguok) catalyzes the first step of the mitochondrial deoxypurine salvage pathway, the phosphorylation of purine deoxyribonucleosides. mutations in the dguok gene have been linked to inherited mitochondrial (mt)dna depletion syndromes, neonatal liver failure, nystagmus, and hypotonia. we now report a novel homozygous c.34c > t (p.arg12x) mutation found in an affected newborn of asymptomatic consanguineous parents. respiratory distress started in the first hours after birth. ...201121534344
hepatitis a seroprevalence among infants aged 12 months in ankara.seroprevalence studies in various age groups contribute to a better understanding of hepatitis a infection and response to hepatitis a immunization. hepatitis a seroprevalence in 12-month-old infants from ankara was studied. among 601 healthy infants, overall hepatitis a seropositivity was found to be 23.5%. there were no gender differences in seropositivity (22.6% for male and 24.5% for female infants). although vaccination of infants would be an ideal prevention strategy, presence of maternal ...201121534354
genetic variation within and between winter wheat genotypes from turkey, kazakhstan, and europe as determined by nucleotide-binding-site profiling.the genetic diversity within wheat breeding programs across turkey and kazakhstan was compared with a selection of european cultivars that represented the genetic diversity across eight european countries and six decades of wheat breeding. to focus the measure of genetic diversity on that relevant to disease-resistant phenotypes, nucleotide-binding-site (nbs) profiling was used to detect polymorphisms associated with the nbs motifs found within the nbs - leucine-rich repeat (lrr) class of resist ...201121534722
an audit of seafood consumption awareness during pregnancy and its association with maternal and fetal outcomes in a turkish population.summary this study was conducted to audit maternal seafood intake awareness during pregnancy and to determine whether there is an association between fish consumption and various pregnancy outcomes. in total, 553 low-risk and healthy pregnant women were given a questionnaire concerning fish consumption. pregnant women who developed gestational diabetes mellitus, pre-term labour-birth, macrosomia, low birth weight and small for gestational age were analysed. fatty fish consumers tended to have hi ...201121534748
allergy epidemics, solidarity and support to countries through pediatric allergy and immunology. 201121535175
pediatric allergy and immunology in turkey.to cite this article: celik g, bakirtas a, sackesen c, reisli i, tuncer a. pediatric allergy and immunology in turkey. pediatr allergy immunol 2011; 22: 440-448. abstract: allergic diseases constitute a significant health problem in turkey. according to a recent multicenter study, which used the isaac questionnaire, the mean prevalence of wheezing, rhinoconjunctivitis, and eczema in 10-yr-old school children during the past year was 15.8%, 23.5%, and 8.1%, respectively. a healthcare level system ...201121535181
the roles of nurses to augment organ donation and transplantation: a survey of nursing students.insufficiency in organ donation from cadavers is a worldwide problem. in turkey, sufficient numbers of organs from cadavers are not available for transplantation; this situation had led to the further growth in the gap between the demand for and availability of organs for transplantation.201121440720
is there any maximum standardized uptake value variation among positron emission tomography scanners for mediastinal staging in non-small cell lung cancer?the maximum standardized uptake value (suv(max)) varies among positron emission tomography-integrated computed tomography (pet/ct) centers in the staging of non-small cell lung cancer. we evaluated the ratio of the optimum suv(max) cut-off for the lymph nodes to the median suv(max) of the primary tumor (ratiosuv(max)) to determine suv(max) variations between pet/ct scanners. the previously described pet predictive ratio (ppr) was also evaluated. pet/ct and mediastinoscopy and/or thoracotomy were ...201121441257
outdoor radioactivity and health risks in balikesir, northwestern turkey.external irradiation from radionuclides naturally present in the environment or released from man-made practices or events is usually an important component of the exposure of human populations. these exposures derive primarily from gamma radiation arising from the decay of these radionuclides at locations outside the human body. the main objective of this study is to evaluate the radioactivity levels and health risks due to terrestrial radionuclides in the soil of balikesir, one of the largest ...201121441564
cost of pneumococcal infections and cost-effectiveness analysis of pneumococcal vaccination at risk adults and elderly in turkey.pneumococcal infections have a substantial burden in turkey, particularly in the elderly (> 60 years) and at-risk adults (18-59 years). vcr are low at approximately 2%. the first aim of this study was the evaluation of the burden of pneumococcal infections (pneumonia and bacteremia) from a public payer perspective in elderly and at-risk adults. the second aim was the evaluation of cost effectiveness of implementing a large ppv program in these populations. a decision tree model was employed usin ...201121441776
heart-type fatty acid binding protein (h-fabp): relationship with arterial intima-media thickness and role as diagnostic marker for atherosclerosis in patients with impaired glucose metabolism;abstract: background: heart type fatty acid binding protein (h-fabp ) has been closely associated with acute coronary syndrome, cardiac abnormalities, stroke, and obstructive sleep disorder in previous studies. the aim of this study was to evaluate and compare the serum h-fabp levels and carotid artery intima-media thickness (cimt) between patients with prediabetes and control subjects. research design and methods we measured serum h-fabp levels in 58 prediabetic patients, 29 with impaired fasti ...201121535886
a dose comparison of olanzapine for the treatment of borderline personality disorder: a 12-week randomized, double-blind, placebo-controlled study.objective: to examine the efficacy and safety of olanzapine at low and moderate doses for the treatment of borderline personality disorder. method: in this 12-week randomized double-blind placebo-controlled trial, 451 outpatients aged 18-65 years with dsm-iv borderline personality disorder received olanzapine 2.5 mg/d (n = 150), olanzapine 5-10 mg/d (n = 148), or placebo (n = 153). the trial was conducted from february 2004 through january 2006 at 59 community-based and academic study centers in ...201121535995
successful prediction of the intra- and extracellular loops of four g-protein-coupled receptors.we present results of the restoration of all crystallographically available intra- and extracellular loops of four g-protein-coupled receptors (gpcrs): bovine rhodopsin (brh), the turkey β-1 adrenergic receptor (β1ar), and the human β-2 adrenergic (β2ar) and a2a adenosine (a2ar) receptors. we use our protein local optimization program (plop), which samples conformational space from first principles to build sets of loop candidates and then discriminates between them using our physics-based, all- ...201121536915
aplasia and agenesis of the frontal sinus in turkish individuals: a retrospective study using dental volumetric tomography.agenesis of the paranasal sinuses is an uncommon clinical condition that appears mainly in the frontal (12%) and maxillary (5-6%) sinuses; in some populations, it appears at a higher proportion. this study investigated the prevalence of agenesis of the frontal sinuses using dental volumetric tomography (dvt) in turkish individuals. the frontal sinuses of 410 patients were examined by dvt scans in the coronal planes for evidence of the absence of the frontal sinuses. a bilateral and unilateral ab ...201121537381
primary cutaneous b-cell lymphoma: subtypes, treatment and outcome of 10 cases. 201121537819
management of a laterally luxated upper incisor caused by the hit of a rifle stock.lateral luxation is the displacement of the tooth in a direction other than axial, which is accompanied by comminution or fracture of the alveolar socket. lateral luxation is one of the most prevalent dental injuries among the general population, resulting in up to 27% of all dental wounds. all physical activities have an associated risk of orofacial injuries due to falls, collisions, and contact with hard surfaces. just like any other training activities, military training exercises present a s ...201121539172
common mefv mutations in iranian azeri turkish patients with behçet's disease.objective: behçet's disease (bd) is an inflammatory disorder of unknown cause with higher prevalence along the ancient silk road. bd shares epidemiological and clinical features with familial mediterranean fever (fmf). moreover, association of bd and certain mefv gene mutations has been described in recent decades. we studied the role of mefv mutations in iranian azeri turkish patients with bd. methods: fifty-three bd patients who met the international study group criteria for bd were analysed f ...201121623663
on-farm study of human contact networks to document potential pathways for avian influenza transmission between commercial poultry farms in ontario, canada.human movements associated with poultry farming create contact networks that might facilitate transmission of avian influenza (ai) between farms during outbreaks. in canada, no information is available about how these networks connect poultry farms. the purpose of this study was to document human contacts between commercial poultry farms in ontario, canada, to learn how ai might be transmitted during outbreaks. we used face-to-face interviews with people entering the farm biosecurity perimeter o ...201121624106
ethnic variation in validity of the estimated obesity prevalence using self-reported weight and height measurements.abstract: background: we examined ethnic differences between levels of body mass index (bmi) based on self-reported and measured body height and weight and the validity of self-reports used to estimate the prevalence of obesity (bmi>=30 kg/m2) in turkish, moroccan, and dutch people in the netherlands. furthermore, we investigated whether bmi levels and the prevalence of obesity in turkish and moroccan people with incomplete self-reports (missing height or weight) differ from those with complete ...201121624122
compliance with mediterranean diet quality index (kidmed) and nutrition knowledge levels in adolescents. a case study from turkey.adopting an eating pattern complying with the mediterranean diet not only decreases body fat mass and obesity risk, but also reduces development of various health problems. this study investigated the nutritional awareness and diet quality mediterranean diet quality index (kidmed) of turkish adolescents. the study was conducted with 890 voluntary participants (464 boys and 426 girls) aged 10-14 years. a questionnaire form was used to learn demographic characteristics of the participants. partici ...201121624407
do mobile phones of patients, companions and visitors carry multidrug-resistant hospital pathogens?a cross-sectional study was conducted to determine bacterial colonization on the mobile phones (mps) used by patients, patients' companions, visitors, and health care workers (hcws). significantly higher rates of pathogens (39.6% vs 20.6%, respectively; p = .02) were found in mps of patients' (n = 48) versus the hcws' (n = 12). there were also more multidrug pathogens in the patents' mps including methicillin-resistant staphylococcus aureus, extended-spectrum β-lactamase-producing escherichia co ...201121624635
fanconi-bickel syndrome in a 3-year-old indian boy with a novel mutation in the glut2 gene.fanconi-bickel syndrome is a rare autosomal recessive disorder characterized by hepatorenal glycogen accumulation, proximal renal tubular dysfunction and impaired utilization of glucose and galactose. most cases have been reported from europe, japan, turkey and the mediterranean belt. we report a 3-year-old boy from southern india who presented with doll-like facies, florid rickets, massive hepatomegaly, growth retardation, renomegaly and laboratory evidence of proximal renal tubular dysfunction ...201121625891
testicular cancer awareness and testicular self-examination among university students.background: this study was planned to determine the knowledge of testicular cancer (tc), risk factors and testicular self-examination (tse) among university students. methods: a survey study was conducted at a university located in ankara, turkey with 634 male students. results: almost half of them (44%) heard tc during their education and life but majority of participants has lack of knowledge about sign and symptoms of tc. only 5.9 % of them (n=38) indicated they received information on tse an ...201121627366
associations of polymorphisms in hpc2/elac2 and srd5a2 genes with benign prostate hyperplasia in turkish men.benign prostate hyperplasia (bph) is the most common benign tumor in elderly men for which the hpc2/elac2 and srd5a2 genes are known genetic factors. the hpc2/elac2 gene features ser217leu and ala541thr polymorphisms and the srd5a2 gene ala49thr and val89leu polymorphisms. the aim of this study was to examine relationships between these polymorphisms and bph in turkish men using amplification by the polymerase chain reaction (pcr) method. polymorphisms were determined by using restriction fragme ...201121627373
sun protection behavior and individual risk factors of turkish primary school students associated with skin cancer: a questionnaire-based study.aim: to determine the turkish primary school students' sun protection behaviors and their individual risk factors associated with skin cancer. methods: the sample of this descriptive study consisted of 6th-8th graders (11-14 age group) from a primary school in the western part of turkey. a self-report questionnaire was administered. the response rate was 86.0 %. results: the mean age of students was 12.8 years (sd =0.73). it was determined that the male students in the age group of 13-14 had mor ...201121627380
risk of breast cancer, health beliefs and screening behaviour among turkish academic women and housewives.background: breast cancer (bc) is one of the most common forms of epithelial neoplasms type of cancer affecting women worldwide. the main objective of this study was to examine health beliefs, screening behavior and risk for developing bc in academic women and housewives in turkey. methods: in this cross-sectional, descriptive study, a sample of 415 women were surveyed, composed of 166 academics and 249 housewives between the ages of 20-65 years. results: risk of developing breast cancer, both f ...201121627390
factors affecting pregnancy outcome of intrauterine insemination cycles in couples with favourable female characteristics.summary the aim of the presented study is to determine the effect of different sperm parameters on the pregnancy rate of intrauterine insemination (iui) cycles in women with favourable fertility characteristics treated for infertility. medical records of 212 infertile couples who had undergone a total of 253 cycles were reviewed retrospectively. inclusion criteria for women were age <35 years, antral follicle count >5, fsh <15 iu/ml, and at least one patent tube documented by hsg or laparoscopy. ...201121627427
which body mass index (bmi) is better in the elderly for functional status?bmi is commonly used indicator of malnutrition and 18.5-24.9kg/m(2) is generally regarded optimal. however, there is an ongoing debate on ideal range for elderly. bmi cut-off values vary also between ethnic groups. we aimed to investigate relationships between bmi, functional status and malnutrition in elderly living in a nursing home in turkey. bmis of 254 residents were calculated. chronic diseases and currently used drugs were noted. functional status was evaluated with katz-activities-of-dai ...201121628078
sporadic-inclusion body myositis (s-ibm) is not so prevalent in istanbul/turkey: a muscle biopsy based survey.in a muscle biopsy based study, only 9 out of 5450 biopsy samples, received from all parts of greater istanbul area, had typical clinical and most suggestive light microscopic sporadic-inclusion body myositis (s-ibm) findings. two other patients with and ten further patients without characteristic light microscopic findings had referring diagnosis of s-ibm. as the general and the age-adjusted populations of istanbul in 2010 were 13.255.685 and 2.347.300 respectively, the calculated corresponding ...201121842592
prevalence of celiac disease in healthy turkish school children.epidemiological studies of celiac disease (cd) in turkey have been performed only within some regions of the country. the aim of this study was to determine the prevalence of cd in turkish school children.201121691340
prevalence and characteristics of restless legs syndrome (rls) in the elderly and the relation of serum ferritin levels with disease severity: hospital-based study from istanbul, turkey.the rls is an underdiagnosed condition, characterized by unpleasant sensations in the legs. pathophysiological mechanisms may include iron deficiency as reflected by low serum ferritin levels and dopaminergic system dysfunction. the purpose of our study was to investigate the prevalence and characteristics of rls in the elderly and the relation of serum ferritin levels with disease severity. ambulatory 1012 (621 women, 391 men, mean age: 73.51-¦7.12 years) consecutive patients above 65 years who ...201121722973
epidemiology of depression in an urban population of turkish children and adolescents.in turkey, studies of childhood depression have been limited to those using only scales.201121683451
does adjuvant antibiotic treatment after drainage of anorectal abscess prevent development of anal fistulas? a randomized, placebo-controlled, double-blind, multicenter study.the risk of fistula formation is a major concern after incision and drainage of an anorectal abscess.201121730779
co-existence of gastrointestinal stromal tumors with other primary neoplasms.gastrointestinal stromal tumors (gists) are the most common primary mesenchymal neoplasms of the tubular gastrointestinal tract (gi). here, we present a series of 32 patients diagnosed with a primary neoplasm in addition to gist, from six different institutions in turkey.201121830398
ethnopharmacological survey of medicinal plants in maden (elazig-turkey).this study aimed to identify wild plants collected for medical purposes by the local people of maden county, located in the eastern anatolia region of turkey, and to establish the uses and local names of these plants.201121704144
anticalcifying nanoparticle antibody titer is an independent risk factor for coronary artery calcification.calcium phosphate deposition is present even in the early phases of the atherosclerotic plaque formation. calcifying nanoparticles (cnps), previously known as nanobacteria, have emerged as a potential causative agent for pathological calcification in human vasculature. this study investigates the relationship between the anti-cnps antibody titers and the extent of coronary calcification.201121709548
effectiveness of a multistimulant home-based program on cognitive function of older adults.the purpose of this study was to test the effects of a multistimulant home-based program on cognitive function among older adults. this study was conducted in northeastern turkey between march and june 2010. it was planned as an experimental versus control two-group design and carried out on 96 (intervention group = 48, control group = 48) participants. the intervention and control groups were similar regarding sex, education, partner status, and continuous drug use. data were collected with a s ...201121685369
the usage of digital radiography and cone beam computed tomography among turkish dentists.objectives: the aim of this study was to determine the prevalence of the use of digital radiography and report how it was used by turkish dentists. methods: the survey was based on 383 dentists who were present at the sixteenth international congress organized by the turkish dental association. a questionnaire which consisted of 19 questions was given to the dentists who participated in the study. data were assessed according to frequency distribution and the ¤ç(2) test was used to determine the ...201121831978
treatment failure of gentamicin in pediatric patients with oropharyngeal tularemia.tularemia is a zoonotic infection, and the causative agent is francisella tularensis. a first-line therapy for treating tularemia is aminoglycosides (streptomycin or, more commonly, gentamicin), and treatment duration is typically 7 to 10 days, with longer courses for more severe cases.201121709631
role of patient chronotype on circadian pattern of myocardial infarction: a pilot study.population-based studies indicate the risk of acute myocardial infarction (ami) is greatest in the morning, during the initial hours of diurnal activity. the aim of this pilot study was to determine whether chronotype, i.e., morningness and eveningness, impacts ami onset time. the sample comprised 63 morning- and 40 evening-type patients who were classified by the horne-östberg morningness-eveningness questionnaire (meq) in the hospital after experiencing the ami. the average wake-up and bed tim ...201121539429
tolerance of two bifora radians bieb populations to als inhibitors in winter wheat.background: bifora radians, an annual weed in winter wheat, is distributed mainly in the mediterranean area, asia minor and the caucasus. it infests winter-sown crops of the central anatolia and middle black sea regions of turkey. field experiments in heavily b. radians-infested fields were conducted over 3 years in samsun, turkey, to determine the response of b. radians to als-inhibiting herbicides, because growers had complained of a decrease in herbicide effect. results: the efficacy of als i ...201121717566
Egg yolk fatty acid profile of avian species - influence on human nutrition.Lipids are an important nutritional component of the avian egg. A review of the literature was completed to determine the fatty acid compositions in egg yolk from some avian species. Additionally, the nutritional influence of lipid and lipoprotein content on the plasma of male participants during 30-day feeding was discussed. The ostrich eggs had the highest unsaturated fatty acid and the lowest cholesterol content in relation to other avian species. Ostrich had a higher proportion of 18:3n-3 (p ...201122035443
qualicopc, a multi-country study evaluating quality, costs and equity in primary care.the qualicopc (quality and costs of primary care in europe) study aims to evaluate the performance of primary care systems in europe in terms of quality, equity and costs. the study will provide an answer to the question what strong primary care systems entail and which effects primary care systems have on the performance of health care systems. qualicopc is funded by the european commission under the "seventh framework programme". in this article the background and design of the qualicopc study ...201122014310
a comprehensive review of the literature on epilepsy in selected countries in emerging markets.to perform a systematic literature review of studies in peer reviewed journals on the epidemiology, economics, and treatment patterns of epilepsy in selected countries in emerging markets.201122003298
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