Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| high detection rate of the oxazolidinone resistance gene optra in enterococcus faecalis isolated from a chinese anorectal surgery ward. | 2016 | 27751624 | |
| pooled analysis of single-dose oritavancin in the treatment of acute bacterial skin and skin-structure infections caused by gram-positive pathogens, including a large patient subset with methicillin-resistant staphylococcus aureus. | oritavancin is a lipoglycopeptide antibiotic with bactericidal activity against gram-positive pathogens, including methicillin-resistant staphylococcus aureus (mrsa). the phase 3 studies solo i and solo ii demonstrated comparable efficacy and safety of a single dose of oritavancin compared with 7-10 days of twice-daily vancomycin in adults with acute bacterial skin and skin-structure infections (absssis). the present analysis assessed clinical responses by pathogen at 48-72 h and at study days 1 ... | 2016 | 27665522 |
| evaluation of the ability of different detergents and disinfectants to remove and kill organisms in traditional biofilm. | the objective of this study was to assess the ability of different detergent and disinfectant combinations to eradicate bacteria in traditional biofilm. | 2016 | 27234012 |
| comparative analysis of saf, protaper next and bt-race in eliminating enterococcus faecalis from long oval canals: an ex vivo study. | comparison of the ability of newly designed rotary files to eliminate viable enterococcus faecalis populations from long oval root canals of extracted human teeth to that of the self-adjusting file (saf). one hundred caries-free, single-rooted, long oval teeth were contaminated with e. faecalis. the teeth were randomly distributed into four groups (n = 25) as follows: g.1, manual; g.2, saf; g.3, protaper next; and g.4, bt-race. two microbial samples were obtained from each tooth with sterile pap ... | 2016 | 27808450 |
| glutathione s-transferase alpha 4 induction by activator protein 1 in colorectal cancer. | glutathione s-transferase alpha 4 (gsta4) is a phase ii detoxifying enzyme that metabolizes electrophiles and carcinogens including 4-hydroxy-2-nonenal (4-hne), an endogenous carcinogen that contributes to colorectal carcinogenesis. in this study, we investigated gsta4 expression and regulation in murine primary colonic epithelial cells, microbiome-driven murine colitis and human carcinomas. exposure of yamc cells to 4-hne induced gsta4 expression. using an inflammation-associated model of color ... | 2016 | 27065323 |
| harnessing bacteriocin biology as targeted therapy in the gi tract. | recently, our laboratory demonstrated that bacteriocins produced by commensal enterococci provide an advantage in niche maintenance in the highly competitive environment of the gastrointestinal (gi) tract. bacterial production of bacteriocins is a conserved defense strategy to help establish an ecological niche. bacteriocin-encoding genes in enterococci are often carried on mobile genetic elements, including conjugative plasmids, enabling the transfer of such traits to other community members in ... | 2016 | 27624536 |
| vertebral osteomyelitis associated with single and mixed bacterial infection in broilers. | vertebral osteomyelitis (vo) is a worldwide emerging disease that affects broilers. the objective of this study was to determine the frequency and aetiology of vo in broilers in a highly productive broiler region. for this, 608 broilers with locomotory problems were analysed from 18 farms. clinical signs were recorded, necropsy was performed and samples were collected from vertebral bodies with gross changes for molecular and histopathological analysis and for bacterial isolation. from broilers ... | 2016 | 27315453 |
| antibacterial efficacy of super-oxidized water on enterococcus faecalis biofilms in root canal. | the success of endodontic treatment depends on a few crucial factors. one of these factors is the complete chemomechanic preparation of root canal against various bacteria. in particular, the effect of resistant bacteria may cause intense pain with flare-up and formation of periapical lesions. therefore, the strong effect of irrigants plays an important role in terms of the complete elimination of these bacteria to achieve long-term successful treatment. | 2016 | 27800142 |
| endocarditis and monocular blindness. | a man aged 77 years with postrenal transplant lymphoproliferative disease was admitted with high fever, elevated inflammatory markers and a heart murmur. blood cultures grew enterococcus faecalis and he was found to have mitral valve endocarditis on echocardiogram and subsequently started on appropriate antibiotics. 5 days into treatment, he developed ocular symptoms and 3 days later, he had irreversible monocular visual loss. he was seen by the ophthalmology team who diagnosed endogenous endopt ... | 2016 | 27797843 |
| draft genome sequence of enterococcus faecalis strain f165 isolated from a urinary tract infection. | we report here a draft genome sequence of enterococcus faecalis strain f165 isolated from a urine specimen in south brazil. the genome size was 3,049,734 bp, with a g+c content of 37.38%, and genes related to antimicrobial resistance and adherence were found in the strain. these findings are consistent with pathogenesis of e. faecalis species. | 2016 | 27795252 |
| antibacterial efficacy of neem (azadirachta indica) extract against enterococcus faecalis: an in vitro study. | debridement and disinfection of the root canal is a crucial step in the success of endodontic treatment. several antimicrobial agents alone or in combination are used to achieve this. the objective of this in vitro study was to assess the antimicrobial efficacy of neem (azadirachta indica) extract against enterococcus faecalis. | 2016 | 27794147 |
| characterization of antimicrobial resistance and quinolone resistance factors in high-level ciprofloxacin-resistant enterococcus faecalis and enterococcus faecium isolates obtained from fresh produce and fecal samples of patients. | the emergence of fluoroquinolone-resistant enterococci is worldwide. antimicrobial resistance was characterized and the effect of quinolone-resistance factors was analyzed in high-level ciprofloxacin-resistant (hlcr) enterococcus faecalis and enterococcus faecium isolated from fresh produce and fecal samples of patients. | 2016 | 27790716 |
| comparative assessment of antimicrobial efficacy of different antibiotic coated gutta-percha cones on enterococcus faecalis an invitro study. | the major goal of endodontic treatment is to eliminate bacteria from the root canals and prevent re-infection. enterococcus faecalis (e. faecalis) has been attributed to be the most common organism for the endodontic treatment failures. the choice of endodontic material that have high antimicrobial efficacy can help in decreasing/avoiding growth of micro-organisms and facilitate the success rate of treatment. | 2016 | 27790583 |
| screening for intestinal colonization with vancomycin resistant enterococci and associated risk factors among patients admitted to an adult intensive care unit of a large teaching hospital. | gut colonization with vancomycin resistant enterococci (vre) increases the risk of acquiring infection during hospital stay. patients admitted in the icu's are the major reservoirs for vre colonization due to higher antibiotic pressure. | 2016 | 27790430 |
| apical sealing ability of mineral trioxide aggregate, intermediate restorative material and calcium enriched mixture cement: a bacterial leakage study. | this in vitro study compared the apical sealing ability of three common root end filling materials namely mineral trioxide aggregate (mta), intermediate restorative material (irm) and calcium-enriched mixture (cem) cement using a bacterial leakage model. | 2016 | 27790267 |
| antibacterial efficacy of different concentrations of sodium hypochlorite gel and solution on enterococcus faecalis biofilm. | this in vitro study compared the antibacterial efficacy of 2.5% sodium hypochlorite gel and 2.5% and 5.25% sodium hypochlorite solutions on enterococcus faecalis (e. faecalis) biofilm. | 2016 | 27790262 |
| the in vitro antibacterial efficacy of persian green tea extract as an intracanal irrigant on enterococcus faecalis biofilm. | the aim of this study was to compare the antibacterial effect of persian green tea extract (gte) and 2.5% sodium hypochlorite (naocl) against enterococcus faecalis (e. faecalis) as an intracanal irrigant. | 2016 | 27790260 |
| antibacterial efficacy of calcium hydroxide and chlorhexidine mixture for treatment of teeth with primary endodontic lesions: a randomized clinical trial. | this study compared the root canal microbial count of necrotic teeth after irrigation with 6% sodium hypochlorite (naocl) (single session treatment) and two-session root canal treatment with two-week application of calcium hydroxide (ch) mixed with 0.2% chlorhexidine (chx) as intracanal medicament. | 2016 | 27790252 |
| nutrient-induced antibiotic resistance in enterococcus faecalis in the eutrophic environment. | nutrient deposition and extensive use of antibiotics are increasing worldwide, especially in freshwater ecosystems. bacteria display resistance to certain antibiotics and thus survive for extended periods in eutrophic environments. in this study, model ecosystems were established to investigate the effect of nitrate and phosphate nutrient salts on antibiotic resistance in strains of enterococcus faecalis. mesocosms were replicated to evaluate the ecological effects of nutrient influx. the mesoco ... | 2016 | 27685672 |
| adjunctive steps for disinfection of the mandibular molar root canal system: a correlative bacteriologic, micro-computed tomography, and cryopulverization approach. | this study evaluated the disinfecting ability of chemomechanical preparation with rotary nickel-titanium instruments, followed by 2 distinct adjunctive procedures in the root canals of extracted mandibular molars by means of a correlative analytical approach. | 2016 | 27641947 |
| in vitro antimicrobial effectiveness of root canal sealers against enterococcus faecalis: a systematic review. | the purpose of this systematic review was to summarize the outcomes of in vitro studies of root canal sealers for their antimicrobial effectiveness against enterococcus faecalis on the basis of direct contact test. | 2016 | 27623499 |
| influence of smear layer on the antimicrobial activity of a sodium hypochlorite/etidronic acid irrigating solution in infected dentin. | the aim of this study was to evaluate the influence of the smear layer on the antimicrobial activity of a 2.5% sodium hypochlorite (naocl)/9% etidronic acid (hebp) irrigating solution against bacteria growing inside dentin tubules. | 2016 | 27616541 |
| comparison of antibacterial effects of 810 and 980- nanometer diode lasers on enterococcus faecalis in the root canal system -an in vitro study. | background and aim: use of laser technology in endodontics has greatly increased in the recent years due to the introduction of new wavelengths and methods and optimal antimicrobial and smear layer removal properties of lasers. this in vitro study aimed to compare the antibacterial effects of diode lasers of 810 nm and 980 nm wavelength on enterococcus faecalis (e. faecalis) biofilm in the root canal system. materials and methods: fifty single-canal human anterior teeth were cleaned, shaped, ste ... | 2016 | 27853346 |
| furostanol saponins from the bulbs of welsh onion, allium fistulosum l. | an extensive phytochemical analysis of the polar extracts from bulbs of welsh onion allium fistulosum l. led to the isolation of nine saponins, four of them, named fistulosaponins g (1a/1b), h (2), i (3a/3b), and j (4), have never been reported previously. fistulosaponins g and i were isolated as a couple of isomers in equilibrium. on the basis of 2d nmr and mass spectrometry data, the structure of the novel compounds were elucidated as (25r)-26-[(β-d-glucopyranosyl)oxy]-3β,22β-dihydroxyfurost-5 ... | 2016 | 27852096 |
| microbe-mediated host defence drives the evolution of reduced pathogen virulence. | microbes that protect their hosts from pathogens are widespread in nature and are attractive disease control agents. given that pathogen adaptation to barriers against infection can drive changes in pathogen virulence, 'defensive microbes' may shape disease severity. here we show that co-evolving a microbe with host-protective properties (enterococcus faecalis) and a pathogen (staphylococcus aureus) within caenorhabditis elegans hosts drives the evolution of reduced pathogen virulence as a by-pr ... | 2016 | 27845328 |
| effects of inactivated enterococcus faecalis on the proliferation and osteogenic induction of osteoblasts. | the present study aimed to evaluate the effects of enterococcus faecalis, inactivated by the common intracanal irrigants sodium hypochlorite (naocl) and chlorhexidine (chx), on osteoblasts. e. faecalis was inactivated with 2% chx or 5.25% naocl. subsequently, the cell counting kit‑8 assay was used to examine the effects of chx‑ and naocl-inactivated e. faecalis on mc3t3‑e1 osteoblast cell proliferation. alizarin red staining was used to determine osteoblast mineralization, and osteogenic inducti ... | 2016 | 27840919 |
| co-evolutionary dynamics between a defensive microbe and a pathogen driven by fluctuating selection. | microbes that protect their hosts from pathogenic infection are widespread components of the microbiota of both plants and animals. it has been found that interactions between 'defensive' microbes and pathogens can be genotype-specific and even underlie the variation in host resistance to pathogenic infection. these observations suggest a dynamic co-evolutionary association between pathogens and defensive microbes, but direct evidence of co-evolution is lacking. we tested the hypothesis that def ... | 2016 | 27862515 |
| comparative assessment of antimicrobial efficacy of different hand sanitizers: an in vitro study. | to evaluate the antimicrobial efficacy of four different hand sanitizers against staphylococcus aureus, staphylococcus epidermidis, pseudomonas aeruginosa, escherichia coli, and enterococcus faecalis as well as to assess and compare the antimicrobial effectiveness among four different hand sanitizers. | 2016 | 27857768 |
| intrathecal/intraventricular linezolid in multidrug-resistant enterococcus faecalis ventriculitis. | background the use of intrathecal antibiotic therapy for the treatment of ventriculitis and/or meningitis has demonstrated efficacy especially when sterilization of the cerebrospinal fluid is not possible with intravenous antibiotics alone. case description we describe the successful treatment of enterococcus faecalis ventriculitis utilizing intrathecal linezolid in a 32-year-old female patient with severe allergy to vancomycin, prohibitive bacterial susceptibilities, and failure of previous att ... | 2016 | 27867829 |
| identification of chemical compounds that inhibit protein synthesis in pseudomonas aeruginosa. | four inhibitory compounds were identified using a poly-uridylic acid (polyu) mrna-directed aminoacylation/translation (a/t) protein synthesis system composed of phenylalanyl-trna synthetases (phers), ribosomes, and ribosomal factors from pseudomonas aeruginosa in an in vitro screen of a synthetic compound library. the compounds were specific for inhibition of bacterial protein synthesis. in enzymatic assays, the compounds inhibited protein synthesis with ic50 values ranging from 20 to 60 μm. min ... | 2016 | 27872201 |
| comparison of antibacterial efficacy of turmeric extract, morinda citrifolia and 3% sodium hypochlorite on enterococcus faecalis: an in-vitro study. | sodium hypochlorite (naocl), the most commonly used irrigant, has many potential properties like its unique ability to dissolve pulp tissue, excellent antimicrobial activity, but has a cytotoxic effect when injected into periapical tissues. it is also known to produce allergic reactions, foul smell and taste, and potential for corrosion. facultative organisms such as enterococcus faecalis and aerobes like staphylococcus aureus are considered to be the most resistant species and one of the possib ... | 2016 | 27891459 |
| comparison of the most common isolates of postoperative endophthalmitis in south korea; enterococcus species vs coagulase-negative staphylococci. | to compare the related factors or manifestations of the two most common isolates of post-operative endophthalmitis, which were enterococcus spp. and coagulase-negative staphylococci (cns) in south korea. | 2016 | 27887598 |
| bactericidal effect of plasma jet with helium flowing through 3% hydrogen peroxide against enterococcus faecalis. | the aim of the present study was to assess the antimicrobial activity of plasma jet with helium (he) flowing through 3% hydrogen peroxide in root canals infected with enterococcus faecalis. a total of 42 single-rooted anterior teeth were prepared, sterilized, inoculated with an e. faecalis suspension and incubated for 7 days. next, the teeth were randomly divided into six experimental groups (including groups treated by plasma jet with or without he for different time durations) and one control ... | 2016 | 27882119 |
| treatment of oral biofilms by a d-enantiomeric peptide. | almost all dental diseases are caused by biofilms that consist of multispecies communities. djk-5, which is a short d-enantiomeric, protease-resistant peptide with broad-spectrum anti-biofilm activity, was tested for its effect on oral multispecies biofilms. peptide djk-5 at 10 μg/ml effectively prevented the growth of these microbes in culture media in a time-dependent manner. in addition to the prevention of growth, peptide djk-5 completely killed both streptococcus mutans and enterococcus fae ... | 2016 | 27880799 |
| microbiological evaluation of the extension wire and percutaneous epidural lead anchor site following a "2-stage cut-down" spinal cord stimulator procedure. | there are concerns regarding bacterial colonization of the temporary extension leads and subsequent infection risk using the 2-stage cut-down approach in spinal cord stimulation (scs). we sought to quantify the extent of bacterial colonization of the temporary extension wire and percutaneous epidural lead anchor site. | 2016 | 27910210 |
| reversible-switch mechanism of the sam-iii riboswitch. | riboswitches are self-regulatory elements located at the 5' untranslated region of certain mrnas. the enterococcus faecalis sam-iii (smk) riboswitch regulates downstream gene expression through conformational change by sensing s-adenosylmethionine (sam) at the translation level. using the recently developed systematic helix-based computational method, we studied the co-transcriptional folding behavior of the smk riboswitch and its shortened construct lacking the first six nucleotides. we find th ... | 2016 | 27934232 |
| assessment of virulence potential of uncharacterized enterococcus faecalis strains using pan genomic approach - identification of pathogen-specific and habitat-specific genes. | enterococcus faecalis, a leading nosocomial pathogen and yet a prominent member of gut microbiome, lacks clear demarcation between pathogenic and non-pathogenic strains at genome level. here we present the comparative genome analysis of 36 e. faecalis strains with different pathogenic features and from different body-habitats. this study begins by addressing the genome dynamics, which shows that the pan-genome of e. faecalis is still open, though the core genome is nearly saturated. we identifie ... | 2016 | 27924951 |
| genome sequence of a commensal bacterium, enterococcus faecalis cba7120, isolated from a korean fecal sample. | enterococcus faecalis, the type strain of the genus enterococcus, is not only a commensal bacterium in the gastrointestinal tract in vertebrates and invertebrates, but also causes serious disease as an opportunistic pathogen. to date, genome sequences have been published for over four hundred e. faecalis strains; however, pathogenicity of these microbes remains complicated. to increase our knowledge of e. faecalis virulence factors, we isolated strain cba7120 from the feces of an 81-year-old fem ... | 2016 | 27924153 |
| in vitro evaluation of the sealing ability of three newly developed root canal sealers: a bacterial microleakage study. | the purpose of this study was to compare the sealing ability of mta fillapex, apatite root canal sealer and ah26 sealers. | 2016 | 27957271 |
| antimicrobial efficacy of different concentration of sodium hypochlorite on the biofilm of enterococcus faecalis at different stages of development. | persistent infection of the root canal due to the presence of resistance bacterial species, such as enterococcus faecalis, has always been one of the most important reasons for endodontic treatment failure. this study investigated the antimicrobial efficacy of 1%, 2.5 % and 5% sodium hypochlorite in eliminating e. faecalis biofilms at different stages of development. | 2016 | 27957257 |
| the sfani restriction-modification system from enterococcus faecalis neb215 is located on a putative mobile genetic element. | 2016 | 27941009 | |
| broad-range 16s rdna pcr on heart valves in infective endocarditis. | infective endocarditis (ie) is diagnosed by blood and/or resected valve cultivation and echocardiographic findings, as defined by the duke criteria. unfortunately, cultures may be negative due to prior antibiotic therapy or fastidious or slow-growing microorganisms. the study aim was to investigate the value of the broad-range polymerase chain reaction (pcr) in addition to blood and valve culture for the detection of causative microorganisms. | 2016 | 27989071 |
| pptab exports rgg quorum-sensing peptides in streptococcus. | a transposon mutagenesis screen designed to identify mutants that were defective in peptide-pheromone signaling of the rgg2/rgg3 pathway in streptococcus pyogenes generated insertions in sixteen loci displaying diminished reporter activity. fourteen unique transposon insertions were mapped to pptab, an abc-type transporter recently described to export sex pheromones of enterococcus faecalis. consistent with an idea that pptab exports signaling peptides, the pheromones known as shps (short hydrop ... | 2016 | 27992504 |
| murine experimental root canal infection: cytokine expression in response to f. nucleatum and e. faecalis. | the aim of this study was to evaluate the gene expression of proinflammatory (rankl, tnf-a and ifn-g) and regulatory (tgf-b and il-10) cytokines as reaction to experimental infection by mono or bi-association of fusobacterium nucleatum (atcc 10953) and enterococcus faecalis (atcc 19433). f. nucleatum and e. faecalis, either in mono- or bi-association were inoculated into the root canal system (rcs) of balb/c mice. animals were sacrificed at 10 and 20 days after infection and periapical tissues s ... | 2016 | 27982237 |
| effect of silver nanoparticles on physicochemical and antibacterial properties of calcium silicate cements. | mineral trioxide aggregate (mta) and portland cement (pc) are calcium silicate cements. they have similar physicochemical, mechanical and biological properties. the addition of zirconium oxide (zro2) to pc provides radiopacity. silver nanoparticles (agnps) may improve some properties of cements. the aim of this study was to evaluate the effect of agnps on physicochemical/mechanical properties and antibacterial activity of white mta (wmta) and pc associated with zro2. the following materials were ... | 2016 | 27982226 |
| draft genome sequence of enterococcus faecalis strain ucd-pd3. | here, we present the draft genome sequence of enterococcus faecalis strain ucd-pd3. the assembly contains 2,861,314 bp in 73 contigs. this strain was isolated from a feral domestic cat (felis catus) anal sac secretion sample, as part of a project on isolating and characterizing the microbes present in feline anal sacs. | 2016 | 27979940 |
| antimicrobial resistance in enterococcus strains isolated from healthy domestic dogs. | enterococci are opportunistic bacteria that cause severe infections in animals and humans, capable to acquire, express, and transfer antimicrobial resistance. susceptibility to 21 antimicrobial agents was tested by the disk diffusion method in 222 enterococcus spp. strains isolated from the fecal samples of 287 healthy domestic dogs. vancomycin and ampicillin minimum inhibitory concentrations (mics) and high-level aminoglycoside resistance (hlar) tests were also performed. isolates showed resist ... | 2016 | 27976593 |
| apical extrusion of intracanal bacteria following use of two engine-driven instrumentation techniques: an in vitro study. | the aim of the present study was to compare in vitro the amount of debris extruded apically from extracted teeth, using twisted files and protaper rotary during two different instrumentation systems. | 2016 | 27965505 |
| rituximab, etoposide, methylprednisolone, high-dose cytarabine, and cisplatin in the treatment of secondary hemophagocytic lymphohistiocytosis with classical hodgkin lymphoma: a case report and review of the literature. | hemophagocytic lymphohistiocytosis is becoming an increasingly recognized disorder in adults. classical hodgkin lymphoma is a relatively uncommon etiology of hemophagocytic lymphohistiocytosis and may complicate treatment options. rituximab, etoposide, methylprednisolone, high-dose cytarabine, and cisplatin are discussed here as a treatment regimen. | 2016 | 27998299 |
| bromomethylthioindole inspired carbazole hybrids as promising class of anti-mrsa agents. | series of n-substituted carbazole analogues bearing an indole ring were synthesized as anti-methicillin-resistant staphylococcus aureus (mrsa) agents from a molecular hybridization approach. the representative compound 19 showed an mic = 1 μg/ml against a panel of mrsa clinical isolates as it possessed comparable in vitro activities to that of vancomycin. moreover, compound 19 also exhibited mic = 1 μg/ml activities against a recent identified z172 mrsa strain (vancomycin-intermediate and daptom ... | 2016 | 27994762 |
| a novel combination approach of human polyclonal ivig and antibiotics against multidrug-resistant gram-positive bacteria. | gram-positive bacteria, especially methicillin-resistant staphylococcus aureus (mrsa) and enterococci, have shown a remarkable ability to develop resistance to antimicrobial agents. | 2016 | 27994476 |
| direct and indirect antibacterial effects of various concentrations of triple antibiotic pastes loaded in a methylcellulose system. | we investigated the direct and indirect (residual) antibacterial effects of various concentrations of triple antibiotic paste (tap) loaded into a methylcellulose system. enterococcus faecalis (e. faecalis) was grown on sterilized dentin blocks (n = 60) and treated with clinically used tap (1,000 mg/ml), low concentrations of methylcellulose-based tap (100, 10, and 1 mg/ml), placebo paste, or 1.5% naocl (n = 10). the pastes were then removed, and biofilm disruption assays were performed. addition ... | 2016 | 28025443 |
| effect of liquid crystalline systems containing antimicrobial compounds on infectious skin bacteria. | this study aimed (i) to prepare liquid crystalline systems (lcs) of glyceryl monooleate (gmo) and water containing antibacterial compounds and (ii) to evaluate their potential as drug delivery systems for topical treatment of bacterial infections. therefore, lcs containing cpc (cetylpyridinium chloride) (lcs/cpc) and phmb (poly(hexamethylene biguanide) hydrochloride) (lcs/phmb) were prepared and the liquid crystalline phases were identified by polarizing light microscopy 24 h and 7 days after pr ... | 2016 | 28028794 |
| the use of different irrigation techniques to decrease bacterial loads in healthy and diabetic patients with asymptomatic apical periodontitis. | diabetes mellitus is a multisystem disease which weakens the human's immunity. subsequently, it worsens the sequelae of apical periodontitis by raising a fierce bacterial trait due to the impaired host response. | 2016 | 28028421 |
| antimicrobial resistance of selected invasive bacteria in a tertiary care center: results of a prospective surveillance study. | we aimed to report the distribution and resistance patterns of eight invasive clinically relevant bacteria surveyed in the clinical center of serbia (ccs) in belgrade. | 2016 | 28036312 |
| cinnamaldehyde inhibits staphylococcus aureus virulence factors and protects against infection in a galleria mellonella model. | bacterial resistance to the available marketed drugs has prompted the search of novel therapies; especially in regards of anti-virulence strategies that aim to make bacteria less pathogenic and/or decrease their probability to become resistant to therapy. cinnamaldehyde is widely known for its antibacterial properties through mechanisms that include the interaction of this compound with bacterial cell walls. however, only a handful of studies have addressed its effects on bacterial virulence, es ... | 2016 | 28066373 |
| structural proteins of enterococcus faecalis bacteriophage ϕef11. | ϕef11, a temperate siphoviridae bacteriophage, was isolated by induction from a root canal isolate of enterococcus faecalis. sequence analysis suggested that the ϕef11 genome included a contiguous 8 gene module whose function was related to head structure assembly and another module of 10 contiguous genes whose products were responsible for tail structure assembly. sds-page analysis of virions of a ϕef11 derivative revealed 11 well-resolved protein bands. to unify the deduced functional gene ass ... | 2016 | 28090386 |
| eradication of enterococcus faecalis biofilms on human dentin. | objectives: this work assesses different methods to interfere with enterococcus faecalis biofilms formed on human dentin slabs. methods: first, methods are presented that select for small molecule inhibitors of biofilm targets using multi-well polystyrene biofilm plates. next, we establish methodologies to study and interfere with biofilm formation on a medically relevant model, whereby biofilms are grown on human root dentin slabs. results: non-conventional d-amino acid (d-leucine) can efficien ... | 2016 | 28082955 |
| biofilm-forming capacity in biogenic amine-producing bacteria isolated from dairy products. | biofilms on the surface of food industry equipment are reservoirs of potentially food-contaminating bacteria-both spoilage and pathogenic. however, the capacity of biogenic amine (ba)-producers to form biofilms has remained largely unexamined. bas are low molecular weight, biologically active compounds that in food can reach concentrations high enough to be a toxicological hazard. fermented foods, especially some types of cheese, accumulate the highest ba concentrations of all. the present work ... | 2016 | 27242675 |
| chemical content, antibacterial and antioxidant properties of essential oil extract from tunisian origanum majorana l. cultivated under saline condition. | essential oils of marjoram were extracted from plants, growing under non-saline and saline condition (75mm nacl). their antioxidant and antibaterial activity against six bacteria (enterococcus faecalis, escherichia coli, salmonella enteritidis, listeria ivanovii, listeria inocula, and listeria monocytogenes) were assessed. result showed that, (i) independently of salt treatment, marjoram essential oils inhibited the growth of most of the bacteria but in degrees. the least susceptible one was ent ... | 2016 | 28375110 |
| high frequency of vancomycin resistant enterococcus faecalis in children: an alarming concern. | enterococcus spp. is considered as important etiological agents of nosocomial infections. however, a little is known about the epidemiology of vancomycin resistant enterococcus faecalis (vref). the aim of this study was to investigate the frequency of vref and detecting of two prevalent resistance genes (vana, vanb) at children medical center hospital, an iranian referral pediatric hospital. | 2016 | 28167857 |
| prevalence of high-level gentamicin-resistant enterococcus faecalis and enterococcus faecium in an iranian hospital. | this study was designed to determine the molecular characteristics and antimicrobial resistance of enterococcal strains isolated from patients admitted to an iranian hospital. enterococcal strains were isolated from the burn patients. all strains were screened for genes encoding resistance to aminoglycoside [aac(6')-ie-aph(2'')-ia, aph (3'), ant (4')], resistance to vancomycin (vana, vanb), resistance to tetracycline (tetk, tetl, tetm, teto), and resistance to erythromycin (erma, ermb, ermc) by ... | 2016 | 28167856 |
| enterococcus faecalis causing delayed spondylodiscitis in a case with retained intraspinal bullet. | delayed presentations have been reported following gunshot wounds (gsw) with retained intraspinal bullets due to migration of projectile or lead intoxication. we report on the rare occurrence of delayed pyogenic spondylodiscitis and neurological dysfunction following injury from low velocity gsw to the spine with a retained projectile. a 55-year-old male presented 4 months following gsw to the abdomen which resulted in colonic injury and l5 fracture. the patient was treated initially with ileo-t ... | 2016 | 28097252 |
| antibacterial efficacy of ah plus and ah26 sealers mixed with amoxicillin, triple antibiotic paste and nanosilver. | background. elimination of bacteria from the root canal system is one of the aims of endodontic treatment; hence the incorporation of antibiotics into sealers can increase their antimicrobial efficacy. the aim of the present study was to determine the in vitro antimicrobial effects of ah26 and ah plus sealers mixed with amoxicillin, triple antibiotic paste and nanosilver on enterococcus faecalis. methods. in this experiment, amoxicillin, triple antibiotic paste and nanosilver powder were added a ... | 2016 | 28096947 |
| root canal irrigation: chemical agents and plant extracts against enterococcus faecalis. | there are various microorganisms related to intra and extra-radicular infections and many of these are involved in persistent infections. bacterial elimination from the root canal is achieved by means of the mechanical action of instruments and irrigation as well as the antibacterial effects of the irrigating solutions. enterococcus faecalis can frequently be isolated from root canals in cases of failed root canal treatments. antimicrobial agents have often been developed and optimized for their ... | 2016 | 28217184 |
| antimicrobial susceptibility patterns: a three-year surveillance study in a rehabilitation setting. | to analyze the susceptibility patterns in a rehabilitation center. | 2016 | 28210371 |
| bacteria in the apical root canals of teeth with apical periodontitis. | bacteria in the tooth root canal may cause apical periodontitis. this study examined the bacterial species present in the apical root canal of teeth with apical periodontitis. antibiotic sensitivity tests were performed to evaluate whether these identified bacterial species were susceptible to specific kinds of antibiotics. | 2016 | 27745799 |
| effects of enterococcus faecalis cect 7121 on cryptosporidium parvum infection in mice. | cryptosporidium is an opportunistic protozoan parasite of humans and animals worldwide and causes diarrheal disease that is typically self-limiting in immunocompetent hosts but often life threatening to immunocompromised individuals. however, there is a lack of completely efficient therapy available. probiotics have attracted the attention as potential antiparasite compounds against protozoa involved in intestinal infections. this study investigated the effects of administration of probiotic ent ... | 2016 | 27193238 |
| evaluation of the amoxicillin concentrations in amniotic fluid, placenta, umbilical cord blood and maternal serum two hours after intravenous administration. | the aims of this study were to evaluate amoxicillin concentrations in amniotic fluid, placenta, umbilical cord blood and maternal blood two hours after intravenous administration to assess obstetric and non-obstetric factors that could have influences on the penetration of the antibiotic into the examined tissues and to analyze the sensitivity to amoxicillin of the most common pathogens isolated from the genital tract. | 2016 | 28231686 |
| antimicrobial resistance and virulence genes in enterococci from wild game meat in spain. | a total of 55 enterococci (45 enterococcus faecium, 7 enterococcus faecalis, and three enterococcus durans) isolated from the meat of wild game animals (roe deer, boar, rabbit, pheasant, and pigeon) in north-western spain were tested for susceptibility to 14 antimicrobials by the disc diffusion method. all strains showed a multi-resistant phenotype (resistance to between three and 10 antimicrobials). the strains exhibited high percentages of resistance to erythromycin (89.1%), tetracycline (67.3 ... | 2016 | 26678143 |
| [histological evaluations on periapical tissues after irradiation by erbium-doped yttrium aluminum garnet laser in labradors dogs]. | to investigate the thermal effects on periapical tissues of labrador dogs after intra-canal irradiation by erbium-doped yttrium aluminum garnet (er:yag) laser at different powers based on the antibacterial experiment of enterococcus faecalis and escherichia coli in root canals with an isthmus, to assess the histological changes, and to prove the safety for clinical applications. | 2016 | 28275785 |
| diversity of antibiotic resistance genes in enterococcus strains isolated from ready-to-eat meat products. | the objective of the study was to answer the question of whether the ready-to-eat meat products can pose indirect hazard for consumer health serving as reservoir of enterococcus strains harboring tetracyclines, aminoglycosides, and macrolides resistance genes. a total of 390 samples of ready-to-eat meat products were investigated. enterococcus strains were found in 74.1% of the samples. a total of 302 strains were classified as: enterococcus faecalis (48.7%), enterococcus faecium (39.7%), entero ... | 2016 | 27780292 |
| identification of vancomycin-susceptible major clones of clinical enterococcus from algeria. | the main objectives of this study were to characterize clinical strains of enterococcus spp. isolated from algerian inpatients and outpatients, to investigate their susceptibility to antibiotics and to analyse their phylogenetic relatedness. a total of 85 non-duplicate enterococcus spp. isolates collected between 2010 and 2013 from various clinical samples, including urine, vaginal swab, pus, blood and semen, from algerian inpatients (n=62) and outpatients (n=23) were identified using matrix-ass ... | 2016 | 27530845 |
| investigating bacterial population structure and dynamics in traditional koumiss from inner mongolia using single molecule real-time sequencing. | koumiss is considered as a complete dairy product high in nutrients and with medicinal properties. the bacterial communities involved in production of koumiss play a crucial role in the fermentation cycle. to reveal bacterial biodiversity in koumiss and the dynamics of succession in bacterial populations during fermentation, 22 samples were collected from 5 sampling sites and the full length of the 16s ribosomal rna genes sequenced using single molecule real-time sequencing technology. one hundr ... | 2016 | 27522429 |
| pitfalls in the identification of enterococcus species and the detection of vana and vanb genes. | the aims were to assess the performance of vitek 2 in identifying enterococcal species and the implementation of genexpert(®) vana/vanb pcr for the detection of vancomycin-resistant enterococci (vre). gram-positive cocci from clinical and environmental specimens (n = 431) suspicious of being enterococci by conventional methods were evaluated by vitek 2. this system identified 296 enterococcus faecium, 87 enterococcus faecalis, 10 enterococcus villorum, 9 enterococcus gallinarum, 9 enterococcus d ... | 2016 | 27367648 |
| macrolide, glycopeptide resistance and virulence genes in enterococcus species isolates from dairy cattle. | the genus enterococcus is known to possess the capacity to acquire and disseminate antimicrobial resistant determinants alongside the ability to produce various virulence genes that enables it to establish infections. we assessed the prevalence and antibiogram profiles of enterococcus spp. in faecal samples of dairy cattle. faecal swab samples were collected from 400 dairy cattle from two commercial cattle farms in two rural communities in the eastern cape, south africa. confirmation of enteroco ... | 2016 | 27166215 |
| influence of a polymerizable eugenol derivative on the antibacterial activity and wettability of a resin composite for intracanal post cementation and core build-up restoration. | eugenol has been used in dentistry due to its ability to inhibit the growth of a range of microorganisms, including facultative anaerobes commonly isolated from infected root canals. the aim of this study was to evaluate the antibacterial activity of the experimental composites containing eugenyl methacrylate monomer (egma), a polymeric derivative of eugenol, against a range of oral bacteria, commonly associated with failure of coronal and endodontic restorations. in vitro composite behavior and ... | 2016 | 27130610 |
| malignant otitis externa in a healthy non-diabetic patient. | a healthy 60-year-old male was initially treated for external otitis, and subsequently received multiple surgeries including abscess drainage, temporal bone debridement, canaloplasty of the external auditory meatus, and fistula excision and was treated with numerous antibiotics at another hospital over a 1-year period. he was seen at our hospital on february 14, 2014 with a complaint of a non-healing wound behind the left ear and drainage of purulent fluid. he had no history of diabetes mellitus ... | 2016 | 26233245 |
| new hydrazines with sulphonamidic structure: synthesis,characterization and biological activity. | infections caused by bacterial species are common in immunocompromised patients and carry significant treatment costs and mortality. the emerging resistance of microorganisms to some synthetic antimicrobial agents makes it necessary to continue the research for new antimicrobial drugs. | 2016 | 24505922 |
| phenotypic and genotypic characterization of bacteriocinogenic enterococci against clostridium botulinum. | the present study aimed to characterize enterococcus faecalis (n = -6) and enterococcus faecium (n = 1) isolated from healthy chickens to find a novel perspective probiotic candidate that antagonize clostridium botulinum types a, b, d, and e. the isolated enterococci were characterized based on phenotypic properties, pcr, and matrix-assisted laser desorption/ionization time of flight (maldi-tof). the virulence determinants including hemolytic activity on blood agar, gelatinase activity, sensitiv ... | 2016 | 27914002 |
| dietary administration of probiotics to sows and/or their neonates improves the reproductive performance, incidence of post-weaning diarrhea and histopathological parameters in the intestine of weaned piglets. | probiotics have gained considerable attention with respect to their beneficial effects on livestock performance and health. the most significant effects of probiotics on the gut microbiota and the host animals take place when they are included in diets during particularly stressful periods such as weaning and/or at the beginning of the lactation period. the probiotics bacillus mesentericus strain to-a at 1 × 10(8) colony forming units (cfu)/g, clostridium butyricum strain to-a at 1 × 10(8) cfu ... | 2016 | 27018090 |
| cesarean section changes neonatal gut colonization. | delivery by means of cesarean section has been associated with increased risk of childhood immune-mediated diseases, suggesting a role of early bacterial colonization patterns for immune maturation. | 2016 | 27045582 |
| effect of united states buckwheat honey on antibiotic-resistant hospital acquired pathogens. | due to an upsurge in antibiotic-resistant infections and lack of therapeutic options, new approaches are needed for treatment. honey may be one such potential therapeutic option. we investigated the susceptibility of hospital acquired pathogens to four honeys from wisconsin, united states, and then determined if the antibacterial effect of each honey against these pathogens is primarily due to the high sugar content. | 2016 | 28292167 |
| epidemiology of multidrug resistant bacterial organisms and clostridium difficile in german hospitals in 2014: results from a nationwide one-day point prevalence of 329 german hospitals. | one important aspect in combatting resistance to antibiotics is to increase the awareness and knowledge by epidemiological studies. we therefore conducted a german-wide point-prevalence survey for multidrug resistant bacterial organisms (mdros) and clostridium difficile (cd) to assess the epidemiology and structure quality of infection control in german hospitals. | 2016 | 27590879 |
| prebiotics and age, but not probiotics affect the transformation of 2-amino-3-methyl-3h-imidazo[4,5-f]quinoline (iq) by fecal microbiota - an in vitro study. | heterocyclic aromatic amines (haas) are carcinogens which are formed in meat cooked using high-temperature methods. the human gastrointestinal (gi) microbiota plays a crucial role in maintaining health in humans of different ages, and especially in the elderly. however, the gi microbiota, whose metabolism and composition changes with age, may also be responsible for the activation of mutagenic substances reaching the colon with diet. probiotics and prebiotics are promising in terms of reducing t ... | 2016 | 27034248 |
| analysis of polyphenolic compounds in extracts from leaves of some malus domestica cultivars: antiradical and antimicrobial analysis of these extracts. | in this study, methanol, ethyl acetate, water extracts, and precipitate were obtained from leaves of malus domestica cultivars: golden delicious, jonagold, elstar, ligol, and mutsu. antiradical activity of these extracts was measured using the abts(+∙) radical, and antimicrobial activity was measured with the disk-diffusion method. phenolic compounds were measured with the colorimetric method and identified with high performance liquid chromatography (hplc). the highest antiradical activity was ... | 2016 | 28097143 |
| the making and taking of lipids: the role of bacterial lipid synthesis and the harnessing of host lipids in bacterial pathogenesis. | in order to survive environmental stressors, including those induced by growth in the human host, bacterial pathogens will adjust their membrane physiology accordingly. these physiological changes also include the use of host-derived lipids to alter their own membranes and feed central metabolic pathways. within the host, the pathogen is exposed to many stressful stimuli. a resulting adaptation is for pathogens to scavenge the host environment for readily available lipid sources. the pathogen ta ... | 2016 | 27720012 |
| 2-alkyl(aryl)-quinazolin-4(3h)-thiones, 2-r-(quinazolin-4(3h)-ylthio)carboxylic acids and amides: synthesis, molecular docking, antimicrobial and anticancer properties. | in this study, a series of novel 2-alkyl(aryl)-quinazolin-4(3h)-thiones, 2-r-(quinazolin-4(3h)-ylthio)carboxylic acids and amides were synthesized and evaluated for antimicrobial and anticancer activities. their structure was confirmed by elemental analysis and spectral data (ft-ir, lc-ms, (1)h-nmr). antimicrobial activity was tested in vitro against staphylococcus aureus, enterococcus faecalis, enterobacter aerogenes, pseudomonas aeruginosa, escherichia coli, klebsiella pneumonia, candida albic ... | 2016 | 25831026 |
| microbial adhesion on novel yttria-stabilized tetragonal zirconia (y-tzp) implant surfaces with nitrogen-doped hydrogenated amorphous carbon (a-c:h:n) coatings. | biomaterial surfaces are at high risk for initial microbial colonization, persistence, and concomitant infection. the rationale of this study was to assess the initial adhesion on novel implant surfaces of enterococcus faecalis, staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, and candida albicans upon incubation. | 2016 | 26612401 |
| synthesis, characterization and antimicrobial activities of novel silver(i) complexes with coumarin substituted n-heterocyclic carbene ligands. | eight new coumarin substituted silver(i) n-heterocyclic carbene (nhc) complexes were synthesized by the interaction of the corresponding imidazolium or benzimidazolium chlorides and ag2o in dichloromethane at room temperature. structures of these complexes were established on the basis of elemental analysis, (1)h nmr, (13)c nmr, ir and mass spectroscopic techniques. the antimicrobial activities of carbene precursors and silver nhc complexes were tested against standard strains: enterococcus faec ... | 2016 | 26740157 |
| microbial ecosystem analysis in root canal infections refractory to endodontic treatment. | the purpose of this study was to combine multiple displacement amplification and checkerboard dna-dna hybridization to qualitatively and quantitatively evaluate the microbiota present in infections refractory to endodontic treatment. | 2016 | 27377440 |
| the structure-antimicrobial activity relationships of a promising class of the compounds containing the n-arylpiperazine scaffold. | this research was focused on in silico characterization and in vitro biological testing of the series of the compounds carrying a n-arylpiperazine moiety. the in silico investigation was based on the prediction of electronic, steric and lipohydrophilic features. the molecules were screened against mycobacterium avium subsp. paratuberculosis cit03, m. smegmatis atcc 700084, m. kansasii dsm 44162, m. marinum camp 5644, staphylococcus aureus atcc 29213, methicillin-resistant s. aureus 63718, escher ... | 2016 | 27681720 |
| antimicrobial metabolites from a marine-derived actinomycete in vietnam's east sea. | two new compounds, a quinoline alkaloid (1) and a 1,4-dioxane derivative (2), were isolated from culture broth of the marine-derived actinomycete micromonospora sp. (strain g019) by bioassay-guided fractionation. this actinomycete strain was isolated from sediment, collected at cát bà peninsula, vietnam. the taxonomic identification was achieved by analysis of 16s rrna gene sequences. on the basis of morphological and phylogenetic evidence, strain g019 was assigned to the genus micromonospora. t ... | 2016 | 26996018 |
| fibrinogen release and deposition on urinary catheters placed during urological procedures. | catheter associated urinary tract infections account for approximately 40% of all hospital acquired infections worldwide with more than 1 million cases diagnosed annually. recent data from a catheter associated urinary tract infection animal model has shown that inflammation induced by catheterization releases host fibrinogen, which accumulates on the catheter. further, enterococcus faecalis catheter colonization was found to depend on ebpa (endocarditis and biofilm-associated pilus), a fibrinog ... | 2016 | 26827873 |
| cloning and purification of the first termicin-like peptide from the cockroach eupolyphaga sinensis. | termicin is an antimicrobial peptide with six cysteines forming three disulfide bridges that was firstly isolated from the salivary glands and hemocytes of the termite pseudacanthotermes spiniger. in contrast to many broad-spectrum antimicrobial peptides, termicin is most active against filamentous fungi. although more than one hundred complementary dnas (cdnas) encoding termicin-like peptides have been reported to date, all these termicin-like peptides were obtained from isoptera insects. | 2016 | 26823660 |
| inhibition of bacterial and fungal pathogens by the orphaned drug auranofin. | we identified auranofin as an antimicrobial compound utilizing a high-throughput screen using a caenorhabditis elegans-staphylococcus aureus infection model. results/methodology: treatment of infected nematodes with auranofin resulted in a prolonged survival rate of 95%, reached with 0.78 μg/ml. further investigation of the antimicrobial activity of auranofin found inhibition against s. aureus, enterococcus faecium and enterococcus faecalis. importantly, the fungal pathogens cryptococcus neoform ... | 2016 | 26808006 |
| in vitro antimicrobial and anti-proliferative activities of plant extracts from spathodea campanulata, ficus bubu, and carica papaya. | african medicinal plants represent a prominent source of new active substances. in this context, three plants were selected for biological investigations based on their traditional uses. | 2016 | 26799575 |
| role of candida albicans secreted aspartyl protease sap9 in interkingdom biofilm formation. | the fungus candida albicans colonizes oral cavity surfaces and is carried by up to 60% of human populations. biofilm development by c. albicans may be modulated by oral streptococci, such as streptococcus gordonii, s. oralis or s. mutans, so as to augment pathogenicity. in this study we sought to determine if the cell wall-associated secreted aspartyl proteinase sap9 was necessary for hyphal adhesin functions associated with biofilm community development. a sap9δ mutant of c. albicans sc5314 for ... | 2016 | 26772652 |
| chemical composition and antimicrobial potential of palm leaf extracts from babaçu (attalea speciosa), buriti (mauritia flexuosa), and macaúba (acrocomia aculeata). | babaçu (a. speciosa), buriti (m. flexuosa), and macaúba (a. aculeata) are palm trees typical of the ecotone area between cerrado and the amazon rainforest. the purpose of this study was to evaluate the antimicrobial potential of the extracts prepared from the leaves of those palms as well as determine their chemical compositions. the ethanol extracts were prepared in a soxhlet apparatus and tested by disk diffusion and agar dilution technique against staphylococcus aureus, enterococcus faecalis, ... | 2016 | 27529077 |
| triterpenoids from acacia ataxacantha dc: antimicrobial and antioxidant activities. | acacia ataxacantha is a medicinal specie used extensively in traditional medicine of benin republic to treat infectious diseases. our previous study showed interesting antibacterial and antifungal activities against six strains of bacteria and six strains of fungi. the aim of this study was to investigate the antimicrobial and antioxidant activities of compounds isolated from a. ataxacantha. | 2016 | 27520306 |