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structure, biological functions and applications of the ab5 toxins.ab(5) toxins are important virulence factors for several major bacterial pathogens, including bordetella pertussis, vibrio cholerae, shigella dysenteriae and at least two distinct pathotypes of escherichia coli. the ab(5) toxins are so named because they comprise a catalytic a-subunit, which is responsible for disruption of essential host functions, and a pentameric b-subunit that binds to specific glycan receptors on the target cell surface. the molecular mechanisms by which the ab(5) toxins ca ...201020202851
induction of apoptosis by shiga toxins.shiga toxins comprise a family of structurally and functionally related protein toxins expressed by shigella dysenteriae serotype 1 and multiple serotypes of escherichia coli. while the capacity of shiga toxins to inhibit protein synthesis by catalytic inactivation of eukaryotic ribosomes has been well described, it is also apparent that shiga toxins trigger apoptosis in many cell types. this review presents evidence that shiga toxins induce apoptosis of epithelial, endothelial, leukocytic, lymp ...201020210553
[the expression of c-myb is strongly associated with the presence of estrogen and progesterone receptors in breast cancer].the c-myb gene was studied in 112 breast cancers. c-myb and estrogen receptor (er) transcripts were found in 78 (70%) and 71 (63%) cancers respectively. of these 71 er positive cancers, 64 (90%) contained c-myb transcripts and of the 41 er negative cancers, 27 (66%) did not contain c-myb mrna. our data show that c-myb transcripts are strongly associated with er and progesterone receptors (p less than 10(-4) status in breast cancer. thus the c-myb expression could be associated with breast cancer ...20102907731
nmr contrast agents for proton imaging. 20102832350
[current approaches to immunological diagnosis of autoimmune and immune complex diseases]. 20102974642
[endodontic approach to injured teeth]. 20102897345
first-trimester prenatal diagnosis for huntington's disease with dna probes.polymorphic dna probes linked to the locus for huntington disease (hd) were used for prenatal diagnosis of a 10-week fetus at 25% risk for the disease. the fetus proved to have a 48% risk of having inherited the hd mutation which was similar to that for the at-risk parent (50%). on this basis the parents elected to terminate the pregnancy. when appropriate family members are available and dna studies are informative, prenatal diagnosis of hd with polymorphic dna probes can determine the at-risk ...20102884412
mixed infections of vibrio cholerae o1 ogawa el tor with shigella dysenteriae.mixed infections caused by enteric pathogens such as bacteria, virus, protozoa and helminthes were reported in different literatures. this report also describes the co-infections caused by vibrio cholerae o1 ogawa el tor with shigella dysenteriae in a patient. a 36-year-old man was admitted in fatemeh zahra hospital of bushehr iran with fever, vomiting and dysentery. his stool sample was cultured, for identification purposes tcbs, xld and other media were used. v. cholerae and s. dysenteriae wer ...201021313886
virulence of environmental stenotrophomonas maltophilia serologically cross-reacting with shigella-specific antisera.this research involved an environmental strain of stenotrophomonas maltophilia which has been reported to produce serological cross-reactivity with shigella dysenteriae type 8 specific antisera. since clinical diagnosis of shigellosis is largely based on culture and serology, the investigation was aimed at in vivo and in vitro virulence comparison between the culturally similar environmental s. maltophilia isolate and the reference s. dysenteriae strains. the findings of this study revealed the ...201021313916
the t cell system in rheumatoid arthritis: activated or defective?rheumatoid arthritis (ra) is characterised by the presence of activated lymphocytes in the synovial compartment, which are classically considered to be of particular importance to the pathogenesis of the disease. we have shown that activated lymphocytes are also found in the rheumatoid lymph nodes and peripheral blood, and that their proportions are increased in early or active disease. double-labelling experiments showed that t cell subsets within the activated circulating lymphocytes resemble ...20103075073
[use of prostacyclin in patients with ischemic stroke. a double-blind method ii].thirty patients with acute ischaemic stroke were allocated randomly into a group treated with prostacyclin and a group receiving placebo. the treatment was started 24 to 72 hours after the onset of stroke. prostacyclin sodium (wellcome, u.k. or chinoin, hpr) or its solvent (glycine buffer) were administered intravenously once daily during 2 weeks in 6-hour infusions. prostacyclin was infused at rates of 2.5-5.0 ng/kg/min. statistically significant improvement appeared from the second day on in t ...20103067105
[use of prostacyclin in patients with ischemic stroke. a double-blind method ii].thirty patients with acute ischaemic stroke were allocated randomly into a group treated with prostacyclin and a group receiving placebo. the treatment was started 24 to 72 hours after the onset of stroke. prostacyclin sodium (wellcome, u.k. or chinoin, hpr) or its solvent (glycine buffer) were administered intravenously once daily during 2 weeks in 6-hour infusions. prostacyclin was infused at rates of 2.5-5.0 ng/kg/min. statistically significant improvement appeared from the second day on in t ...20103067105
anti-idiotypic antibodies: a new generation of vaccines against infectious agents.anti-idiotypic antibodies have been suggested recently as candidates for potential vaccines against numerous infectious organisms. these antibody-based vaccines might represent a new generation of vaccines for inducing protective immunity in susceptible hosts.20103153167
letter: evaluation of laboratory tests. 20104137770
letter: evaluation of laboratory tests. 20104137770
extracellular accumulation of proline, serine and trehalose in the haemolymph of osmoconforming brackish-water mosquitoes.larvae of culex tarsalis, a mosquito, are capable of surviving and developing in dilutions of sea water ranging from 0 mosmol l-1 to 700 mosmol l-1. in waters more dilute than 400 mosmol l-1, the larvae osmoregulate, whereas in those more concentrated than 400 mosmol l-1, the osmotic strength of the haemolymph parallels that of the medium, i.e. the larvae osmoconform. over the full range of external concentrations tested, the larvae regulate the levels of na+, k+, mg2+, ca2+ and cl- in the haemo ...20103108441
congenital adrenal hyperplasia. 20102887945
the versatility of hydroxyapatite blocks in maxillofacial surgery.there is considerable interest at present in the potential role of calcium hydroxyapatite as a biomaterial for bone augmentation in oral and maxillofacial surgery. most of the published work has been on the particulate form, mainly in alveolar ridge procedures. however, hydroxyapatite is also available as solid or porous blocks. the blocks are more predictable in their use than are the particles, and are adaptable and versatile. this paper reviews the biological behaviour of the material and dis ...20102825758
functional significance of the kunitz-type inhibitory domains of lipoprotein-associated coagulation inhibitor.blood coagulation can be initiated when factor vii or viia, a plasma protease, binds to its essential cofactor, tissue factor (tf), and proteolytically activates factors ix and x, triggering a cascade of events which eventually leads to the formation of thrombin and a fibrin clot. plasma contains a lipoprotein-associated coagulation inhibitor (laci) which inhibits activated factor x (xa) directly and, in a xa-dependent way, inhibits vii(a)/tf activity, presumably by forming a quaternary xa/laci/ ...20102927510
should doctors control discharge? the case for; the case against. 20103347537
carbohydrate structures of nonspecific cross-reacting antigen-2, a glycoprotein purified from meconium as an antigen cross-reacting with anticarcinoembryonic antigen antibody. occurrence of complex-type sugar chains with the gal beta 1----3glcnac beta 1----3gal beta 1----4glcnac beta 1----outer chains.nonspecific cross-reacting antigen-2 (nca-2) is a glycoprotein purified from meconium as a closely correlated entity with carcinoembryonic antigen (cea). as in the case of cea, only asparagine-linked sugar chains are included in nca-2. in order to elucidate the structural characteristics of the sugar chains of nca-2, they were quantitatively released from the polypeptide backbone by hydrazinolysis and reduced with nab3h4 after n-acetylation. the radioactive oligosaccharides were fractionated by ...20102808357
effects of rice fiber on fecal weight, apparent digestibility of energy, nitrogen and fat, and degradation of neutral detergent fiber in young men.the effects of rice fiber on fecal weight, transit time, frequency of defecations, digestibility of nutrients and blood status were investigated in 5 healthy young men. each of them consumed a brown rice diet and then a polished rice diet for 2 weeks respectively. both diets contained 1.2 g protein per kg body weight. the brown rice diet contained 2 times as much dietary fiber as the polished rice diet. when they consumed the brown rice diet, it showed an increase of fecal weight and decrease of ...20103035151
plasma atrial natriuretic peptide concentrations during induction of anesthesia and acute volume loading in patients undergoing cardiac surgery.induction of anesthesia with fentanyl for coronary artery bypass grafting decreased (p less than .05) plasma atrial natriuretic peptide (anp) concentrations from awake values in twelve patients. during a steady state of anesthesia before surgery, isotonic saline solution (10 ml/kg) was infused simultaneously with the elevation of the lower extremities in six patients, while six subjects served as controls receiving no volume loading and having no leg raising. the anp levels returned to the awake ...20102980951
[pathological aging of the brain. personal observations on the use of citicoline]. 20102973933
[nutrition in the etiology of breast cancer. results of a survey in austria]. 20102934651
anticholinergic drugs in the treatment of airways disease. 20102861843
principles of the diagnostic system 'orfèvre' for computerized analysis in radiology. 20102980470
attractive propositions: microbial responses to chemical signals. 20103153179
[therapy of carcinoma in situ]. 20104034075
lowering effect of pantethine on plasma beta-thromboglobulin and lipids in diabetes mellitus.pantethine in a dosage of 600 mg for the first 3 months, and in a dosage of 1200 mg for the second 6 months was given to 16 diabetics in whom plasma beta-thromboglobulin was raised (greater than 50 ng/ml). plasma beta-tg levels decreased significantly with pantethine treatment for 9 months. plasma triglyceride, total cholesterol, apo e and apo cii levels decreased significantly after 9 months. plasma ldl-c and atherogenic index (ldl-c/hdl-c ratio or apo b/apo ai ratio) tended to decrease with tr ...20102963604
blood concentration and urinary excretion of enalapril in patients with chronic renal failure. 20103003431
comparison of atracurium and d-tubocurarine for prevention of succinylcholine myalgia.we compared the incidence of postoperative myalgia (pom) and fasciculations when atracurium (atr) or d-tubocurarine (dtc) was given prior to succinylcholine (sdc) for tracheal intubation in 44 asa class i or ii outpatient females undergoing laparoscopy. the subjects were assigned to one of three groups: group 1 received 0.025 mg/kg atr; group 2 received 0.05 mg/kg dtc; and group 3 received saline (ns), all in a double-blind manner. thiopental was administered 1 min and 45 sec after pretreatment ...20102955717
antiprotease capacity in acute pancreatitis.serial measurements of circulating antiproteases were carried out on 42 consecutive patients admitted with acute pancreatitis. in the 7 days following admission the serum levels of alpha 1 antitrypsin (alpha 1 at), alpha 1 antichymotrypsin (alpha 1 act) and the trypsin inhibitory capacity (tic) increased by more than 300 per cent. the serum concentration of alpha 2 macroglobulin (alpha 2 m) alone showed a decline which was most profound in those patients with severe acute pancreatitis. initial e ...20103768647
focus on scotland. taking the high road. interview by sue smith. 20102920555
[clinical survey on adverse reactions of contrast media (2d report)]. 20102950377
[horizontal laparotomy in biliary tract surgery].for operations on the biliary tract the transverse horizontal incision has the same advantages as the subcostal approach: strong abdominal wall, little influence on ventilation and wide access to the subhepatic region. but in addition, the abdominal wall nerves are preserved as much as possible, post-operative evisceration, it is occurs, can easily be repaired and subsequent surgery can be performed using the same route.20102934697
neuron-specific enolase in the diagnosis of small-cell lung cancer with pleural effusion: a negative report.we measured the concentration of neuron-specific enolase (nse) and carcinoembryonic antigen (cea) in the serum and pleural fluid of 53 patients with pleural effusions, including seven patients with small-cell lung cancer (sclc). high levels (above 12.5 micrograms.l-1) of nse in pleural fluid were observed in five patients with sclc (sensitivity 71%). however, pleural fluid nse levels were also increased in five patients with other types of cancer and in four patients with non-malignant inflammat ...20102853080
transfer of pre-embryos donated and fertilized in vivo to recipients given a steroid replacement therapy.this study describes eleven procedures of non-surgical recovery of preimplantation conceptuses from the uteri of eight fertile donor women and the transfer of the recovered pre-embryos into the uteri of infertile recipients with primary ovarian failure, or with hypothalamic--pituitary failure. conjugated oestrogens and progesterone were administered to recipients as replacement steroids during the first 20 weeks of pregnancy, in order to produce a secretory endometrium allowing nidation and deve ...20102851614
midazolam in the intensive care unit. 20103769775
why does placebo improve severe limb ischaemia? 20102893161
[the treatment of severe, therapy-resistant depression using infusions of antidepressants].infusion-therapy with antidepressants has been of value in severe as well as therapy resistant depressive states. in addition to doses lower than those used for oral treatment, a more rapid onset of therapeutic effect and a better tolerance, the beneficial effect seems also to depend on the setting in which the treatment takes place. infusion-therapy is a combined pharmacopsychotherapeutic procedure. next to infusion-treatment a pretreatment with neuroleptics is advised either via the oral or pa ...20102922514
validity of an operational definition for neurotic unipolar major depression.after we reviewed the literature to identify the clinical and phenomenologic correlates of neurotic depression, we constructed a 6-item operational definition to distinguish neurotic unipolar major depressive disorder from non-neurotic major depression. the neurotic depressives were characterized by a low rate of abnormal dexamethasone suppression test (dst) results and a strong family history of alcoholism. neurotic depressives improved less than non-neurotic depressives during the index hospit ...20102952692
uptake of 63ni2+ in the central and peripheral nervous system of mice after oral administration: effects of treatments with halogenated 8-hydroxyquinolines.oral administration of 63ni2+ to mice resulted in higher levels of the metal in the sciatic nerves, the trigeminal ganglia, spinal nerve roots and the spinal cord than in the cerebellum and the frontal cortex. in the sciatic nerves, the trigeminal ganglia and the spinal nerve roots a high vascular permeability may explain the preferential uptake of the 63ni2+. the higher accumulation of the 63ni2+ in the spinal cord than in the examined structures of the brain may be related to a diffusion from ...20102916242
continuous ecg monitoring of children with cancer receiving domperidone.domperidone is an effective antiemetic for children receiving cytotoxic therapy. there have been reports of cardiac arrest in older patients associated with domperidone. we carried out continuous ecg monitoring of 18 children receiving domperidone intravenously in a dose of 1 mg/kg body weight. no serious dysrhythmias were noted during 379 h of recording. single premature beats, transient sinus pauses, and nodal block were occasionally associated with vomiting and were no more common than would ...20103153247
arrhythmia or artifact? 20102916599
[screening of cancer, advantages and disadvantages]. 20102916263
the ir-thy-1 concept: continuing saga. 20102876044
ptsd and suicide attempts by adolescents. 20102929769
exposure to benzodiazepines in utero. 20102884529
[hismanal--a new nonsoporific hay fever medication]. 20102876531
consent and the young mother. 20102857392
immunology and the anaesthetist. 20103768621
statistical methodology in the analysis of relationships between dna polymorphisms and disease: putative association of ha-ras-i hypervariable alleles and cancer. 20103279763
fatal asthma in a subject sensitized to toluene diisocyanate.we report the case of a 43-yr-old car painter who died within 1 h of exposure to a polyurethane paint in the workplace. a diagnosis of asthma induced by toluene diisocyanate (tdi) had been established 6 yr before, when he underwent inhalation challenges with carbachol and with tdi. the subject had airway hyperresponsiveness to carbachol (pd20fev1 carbachol = 0.32 mg; normal value greater than 1.0 mg) and developed an early and long-lasting asthmatic reaction after exposure to tdi in the laborato ...20102849334
generation and recognition of leukotriene mediators of hypersensitivity and inflammation.the potent mediators generated by the 5- and 15-lipoxygenation of arachidonic acid have diverse effects on smooth muscles, blood vessels, leukocytes, epithelial cells and glands, and sensory neurons, which suggest possible roles in the initiation and regulation of physiological and biochemical events. the responses to leukotrienes and related mediators are attributable to binding by stereospecific cellular receptors and consequent activation of biochemical transductional sequences analogous to t ...20102831014
[position of surveillance therapy in clinical stage i testicular non-seminoma].since the initiation of a 'surveillance' therapy the role of retroperitoneal lymph node dissection as standard treatment in the management of patients with clinical stage i nonseminomatous germ cell testicular tumor (nsgctt) continues to be debated. noninvasive staging techniques (ct scans, lymphography, ultrasound and serologic tumor markers) help to identify more accurately patients with distant metastases. 'surveillance' alone as a possible treatment modality following orchidectomy in selecte ...20102834854
pharmacokinetics of adriamycin, adriamycinol, and antipyrine in patients with moderate tumor involvement of the liver.the pharmacokinetics of adriamycin, its metabolite adriamycinol, and antipyrine were studied in 17 patients with moderate tumor involvement of the liver and compared to that of 19 tumor patients with normal liver function (preiss et al. 1985). the individual liver function parameters deviated from normal by a factor ranging from 2.5 to 12.2. the t1/2 alpha and t1/2 beta, the auc (corrected for body weight and dose) and the total body clearance (cl, corrected for body weight) of adriamycin did no ...20102824523
[alternative treatment. anthroposophical medicine would create "balance"]. 20103645889
the hypothalamic-pituitary-adrenal axis in depression. 20103035885
the use of dura mater allograft in the surgical repair of large defects of the abdominal wall.the dura mater allograft is being used as an abdominal fascia substitute and major advantages are documented. it was used successfully in four patients at this institution, with a ten month follow-up period. its strength, durability, tissue tolerance, flexibility, ease of handling, nonallergenic property, availability and stability in the presence of infection make it a good graft to be used in the repair of large abdominal hernias. we are quite convinced that long term follow-up results will ve ...20103160130
the use of dura mater allograft in the surgical repair of large defects of the abdominal wall.the dura mater allograft is being used as an abdominal fascia substitute and major advantages are documented. it was used successfully in four patients at this institution, with a ten month follow-up period. its strength, durability, tissue tolerance, flexibility, ease of handling, nonallergenic property, availability and stability in the presence of infection make it a good graft to be used in the repair of large abdominal hernias. we are quite convinced that long term follow-up results will ve ...20103160130
desirable standards of performance for therapeutic drug monitoring.therapeutic drug monitoring is an important aspect of clinical chemistry for which no objective analytical goals yet exist. based on fundamental pharmacokinetic theory, and the current consensus strategy for analytical goal-setting for precision based upon biological variation, a theoretical model allows derivation of the goal that: analytical cv less than or equal to 1/4 [(2t/t - 1)/(2t/t + 1)] x 100%, where t is the time interval between doses, and t is the average elimination half-life. using ...20103815803
the incidence of cardiac arrhythmias during intravenous digital subtraction angiography: a comparison of peripheral and central injections.intravenous digital subtraction arteriography (iv-dsa) was carried out in 204 patients with arteriosclerotic peripheral vascular disease using the non-ionic contrast medium iopamidol 370. in 124 patients the injection was made into an antecubital vein and in 80 into the right atrium. rhythm strip electrocardiograms showed no significant difference in incidence or type of arrhythmias between either injection method (p greater than 0.95).20102941437
anal duct carcinoma. 20102924675
abnormal systolic time intervals in obesity and their relationship with the amount of overweight.we studied 17 severely obese subjects (age range 26 to 42 years), without hypertension, diabetes mellitus, angina, or clinical signs of heart failure or respiratory disease, and 16 age-matched control subjects. x-teleroentgenographic findings (transverse cardiac diameter and cardiothoracic ratio), blood pressure, and mechanocardiographic parameters were analyzed in both groups. by means of conventional simultaneous recordings of ecg, phonocardiogram, and carotid pulse (100 mm/sec), systolic time ...20102943149
[the importance of physiopathology in the management of peptic ulcer]. 20092772478
[diagnosis and treatment of neuroblastoma in children--analysis of 98 patients].from 1959 to 1982, 98 patients with neuroblastoma were treated in our hospital. seventy-eight were diagnosed by pathology and 69 (88.5%) were followed for 1 approximately 18 years. 50(51%) had already had distant metastasis (22, to bone) on admission. operation was performed on 53 patients (total excision on 18, partial excision on 11 and biopsy on 24 patients). the 1 and 15 year survival rates were 31.4% and 12.9%. the survival curve levelled off from the second year of the operation and remain ...20093769741
[sudden death of a young adult and right ventricular cardiomyopathy]. 20093207241
cognitive and social-emotional development of children in different preschool environments.62 english-speaking preschool children were divided into three groups, a montessori group (n = 21), a traditional preschool group (n = 21), and a homestaying group (n = 20) to compare their relative cognitive and social-emotional development. significant differences in favour of the school groups were found for vocabulary, language comprehension, ability to judge the correctness of figural stimuli, visual memory, and perceptual organization. no differences were found for social-emotional develop ...20092798666
cognitive and social-emotional development of children in different preschool environments.62 english-speaking preschool children were divided into three groups, a montessori group (n = 21), a traditional preschool group (n = 21), and a homestaying group (n = 20) to compare their relative cognitive and social-emotional development. significant differences in favour of the school groups were found for vocabulary, language comprehension, ability to judge the correctness of figural stimuli, visual memory, and perceptual organization. no differences were found for social-emotional develop ...20092798666
[a three years follow-up study on the blood pressures of 6111 children in chengdu].this paper reports the results of a follow-up study in blood pressures of 6111 children for 3 years in chengdu city and the villages around. it was showed that the blood pressure for both the city and village children were elevated in overall with age. among the city children, the rate of bp-rising varied in different periods of childhood and that of girls above 13 was not significant. among village children, the rate of bp-rising for both male and female comparison to that of urban ones were si ...20092736619
sonographic and pathological staging of patients with clinically localized prostate cancer.we evaluated 64 patients with clinically localized prostate cancer (on the basis of rectal examination, serum acid phosphatase, bone scan and pelvic computerized tomography scan) by transrectal sonography before radical prostatectomy. of the 48 patients with histologically proved localized prostate cancer sonography overstaged the disease in 5 (10%) and correctly staged it in 43 (90%). all overstaged cancer patients were scanned after either prostatic biopsy (4) or transurethral prostatectomy (1 ...20092681836
introduction to immunocytochemistry.immunocytochemistry has opened a new era in research and diagnosis. the development of immunocytochemical methods has made it possible to identify in situ normal and pathological tissue constituents, which it has not been possible to detect using ordinary histological methods. however, immunocytochemical techniques involve several pitfalls, which without proper control protocols can easily lead to incorrect findings. when interpreting the results obtained, account must always be taken of the mor ...20092664772
pulmonary aspergillosis in immunosuppressed patients with haematological malignancies.invasive pulmonary aspergillosis as a cause of mortality and morbidity in patients with haematological malignancies is becoming more common. predisposing factors are powerful immunosuppressive chemotherapy, neutropenia and synergistic combinations of antibiotics of great potency and wide spectrum of activity. clinical and radiological signs are heterogeneous, sometimes misleading and often absent. treatment is often empirical on suspicion alone. amphotericin b is the only effective drug but it h ...20093749452
problems associated with the use of immediately dangerous to life and health (idlh) values for estimating the hazard of accidental chemical releases.the possibility of accidental industrial chemical releases has generated considerable recent attention. one area requiring research for emergency planning is the development of safe exposure concentrations for the public in the event of an inadvertent release. the united states environmental protection agency (epa) has established a list of extremely hazardous substances and suggested that the toxicity ranking for 92 hazardous materials could be based on the "immediately dangerous to life or hea ...20092688389
griseofulvin and ketoconazole in the treatment of dermatophyte infections. 20092666321
hodgkin's disease and non-hodgkin's lymphomas. 20092670408
near-miss asphyxiation from a toy ball: a small parts failure.the case report of a near-fatal asphyxiation of an 11-month-old child by a 26 mm (diameter) toy ball is presented. the lack of compliance with existing consumer product safety commission standards for small parts is discussed, and a recommendation is made regarding the coloring of ingestible objects.20092710666
structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced neurotoxicity. ii. evaluation of the biological activity of the pyridinium metabolites formed from the monoamine oxidase-catalyzed oxidation of mptp analogs.in the accompanying paper, several tetrahydropyridine analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) were screened for their abilities to be oxidized by monoamine oxidase (mao) to pyridiniums and to produce neurotoxicity in mice. we reported that most of the analogs were oxidized by mao to pyridiniums and some of the analogs were neurotoxic. we concluded that the capacity of a tetrahydropyridine mptp analog to be oxidized by mao to a pyridinium was a necessary, but not sufficient ...20092786565
intraoperative staging in ovarian cancer.in patients with early stage i or ii ovarian cancer a meticulous staging laparotomy is required; this should include omentectomy, pelvic and paraaortic lymphadenectomy, multiple peritoneal biopsies and diaphragmatic biopsies. adjunctive therapy is based on these surgical-pathological findings. in patients with advanced disease (stages iii and iv) it has been demonstrated that optimal tumour reduction enhances the length of survival. a complete resection of all gross disease in the abdominal cavi ...20092661086
dislocated jaw. 20092742562
management of acute asthma. 20092713796
who issues report on heavy metal and pah compounds from municipal incinerators. 20092754439
fibrinogen nagoya, a replacement of glutamine-329 by arginine in the gamma-chain that impairs the polymerization of fibrin monomer.structural studies on a hereditary abnormal fibrinogen, fibrinogen nagoya (takamatsu, j., ogata, k., kamiya, t., koie, k., takagi, t., & iwanaga, s. (1979) thromb. haemost. 42, 78), were performed to identify the abnormality responsible for the impaired polymerization of fibrin monomer. upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reducing conditions, fibrinogen nagoya showed the presence of an extra protein band with an apparent molecular weight of 49,500 in addition to ...20092738036
[dynamics of bile secretion under stressful conditions]. 20092702266
[cataract surgery 220 years ago].the author reports on the first 14 cataract extractions performed by karl kaspar von siebold, a würzburg surgeon, in 1766/67. he used daviel's method. at that time there was no anesthesia, no sterility or even antisepsis, and no optical correction of aphakia for his patients. four eyes were lost due to infection and another four had much poorer vision after surgery due to irregular corneal scarring. in six cases both patient and physician were satisfied with the result. siebold's case reports ex ...20092689768
[nursing career development program by private industry--from job management to career management]. 20092615507
a ruptured cerebral aneurysm from choriocarcinomatous origin--a case report and a review.a case of a ruptured metastatic aneurysm of choriocarcinoma is reported. the fourteen other cases of the literature are summarized. the pathological significance of this rare presentation of metastatic disease is discussed. the treatment of choice is defined as excision followed by chemotherapy and whole brain irradiation. the prognosis remains poor.20092747937
[osteolytic foci: cancer or not?]. 20092797229
species differences in the pharmacology of terminal 5-ht autoreceptors in mammalian brain. 20092665245
the incidence and significance of seminal vesicle invasion in patients with adenocarcinoma of the prostate.the incidence and significance of seminal vesicle invasion in patients with adenocarcinoma of the prostate were determined in 139 patients who underwent radical prostatectomy. of the 36 patients who had seminal vesicle invasion, 27 (75%) also had capsular invasion and 13 (43%) had lymph node metastases. disease progression rates were 31% and 58% at 5 and 8 years, respectively. survival rate at 5 years was 90.6% and at 8 years it was 83.7%. of the 103 patients without seminal vesicle invasion, 21 ...20093815316
assessment of the character and incidence of electrocardiographic changes in children with simple obesity.the studied group comprised 82 children with simple obesity. in the group the character and frequency of ecg changes in 12 conventional leads were analyzed. a correlation was established between the character and frequency of these changes and the degree of overweight and obesity duration. in children with simple obesity a considerable prevalence was observed of disturbances of sinus rhythm, impairment of intraventricular conduction and signs of left ventricular hypertrophy. the observed changes ...20093837606
assessment of the character and incidence of electrocardiographic changes in children with simple obesity.the studied group comprised 82 children with simple obesity. in the group the character and frequency of ecg changes in 12 conventional leads were analyzed. a correlation was established between the character and frequency of these changes and the degree of overweight and obesity duration. in children with simple obesity a considerable prevalence was observed of disturbances of sinus rhythm, impairment of intraventricular conduction and signs of left ventricular hypertrophy. the observed changes ...20093837606
blood clonal b cell excess (cbe) at diagnosis in patients with non-hodgkin lymphoma (nhl). relation to clinical stage, histopathology and response to treatment.untreated non-leukemic (lymphocytes less than or equal to 4.0 x 10(9)/l) patients with non-hodgkin lymphoma (nhl) of b cell type often show an excess of b cells in peripheral blood bearing the same light chain isotype as the lymph node tumor cells which may indicate a leukemic spread of the disease. the ratio between kappa- and lambda-bearing lymphocytes (normal range 1.0-3.3) was studied to evaluate the prognostic significance of clonal b cell excess (cbe) at diagnosis in 110 nhl patients. in t ...20093115783
[computerized tomography symptoms in 2 cases of primary linitis plastica of the rectum]. 20092844723
utilization of formal social support services by non-institutionalized ill elderly. 20092948279
surrogate dentist: domestic medical guides and oral health care in the nineteenth century. 20092700922
[demands for quality and planning standards for model casting]. 20092697127
convergence to stationary distributions in two-species stochastic competition models.two sets of sufficient conditions are given for convergence to stationary distributions, for some general models of two species competing in a randomly varying environment. the models are nonlinear stochastic difference equations which define markov chains. one set of sufficient conditions involves strong continuity and phi-irreducibility of the transition probability for the chain. the second set has a much weaker irreducibility condition, but is only applicable to monotonic models. the results ...20092769087
lead toxicity and iron deficiency in utah migrant children.we determined the frequency of presumptive iron deficiency and lead toxicity in 198 utah migrant children, ages 9-72 months, during the summer of 1985. there were no confirmed cases of lead toxicity. thirteen per cent of those tested and 30 per cent of the children ages 9-23 months were iron deficient. hematocrit determinations accurately predicted iron deficiency in only 35 per cent of the children confirmed to have this disorder via erythrocyte protoporphyrin screening.20092650572
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