Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| protozoan and helminth parasite fauna of free-living croatian wild wolves (canis lupus) analyzed by scat collection. | the european wolf (canis lupus) is a large carnivore species present in limited areas of europe with several small populations still being considered as endangered. wolves can be infected by a wide range of protozoan and metazoan parasites with some of them affecting free-living wolf health condition. on this account, an epidemiological survey was conducted to analyze the actual parasite fauna in croatian wild wolves. in total, 400 individual faecal samples were collected during field studies on ... | 2017 | 28043382 |
| molecular identification of ancylostoma species from dogs and an assessment of zoonotic risk in low-income households, são paulo state, brazil. | hookworm infection stands out for its worldwide distribution and for its veterinary and public health relevance. based on copromicroscopic examinations and polymerase chain reaction (pcr) amplification of the its1-5.8s-its2 region, we assessed, respectively, the prevalence of intestinal parasites and the identification of canine hookworm species in faeces recovered from 278 dogs living in households of an inland municipality of são paulo state, brazil. intestinal parasites were found in 67.3% of ... | 2017 | 26752269 |
| [potential hazard of zoonotic parasites present in canine feces in puerto escondido, oaxaca]. | to estimate the zoonotic parasites prevalence in feral dog feces in puerto escondido. | 2017 | 25604414 |
| diffuse unilateral subacute neuroretinitis caused by ancylostoma hookworm. | diffuse unilateral subacute neuroretinitis is an ocular infectious disease caused by several distinct nematodes. definite identification of the involved nematodes is rarely achieved. we report on the molecular-based genetic identification of an ancylostoma ceylanicum hookworm implicated in a case of diffuse unilateral subacute neuroretinitis in a child. | 2017 | 28098549 |
| intestinal parasites of children and adults in a remote aboriginal community of the northern territory, australia, 1994-1996. | parasitic infections can adversely impact health, nutritional status and educational attainment. this study investigated hookworm and other intestinal parasites in an aboriginal community in australia from 1994 to 1996. | 2017 | 25960921 |
| seroprevalence of five parasitic pathogens in pregnant women in ten caribbean countries. | to date, published epidemiological studies of parasitic infections in humans in the caribbean region are very limited. here, we report the seroprevalence of five parasitic pathogens, including ascaris lumbricoides, entamoeba histolytica, giardia lamblia, schistosoma mansoni, and toxocara canis in 435 serum samples collected between 2008 and 2011 from pregnant women in ten caribbean islands. we tested the serum samples for igg antibodies against the five parasites by enzyme-linked immunosorbent a ... | 2017 | 27778108 |
| more bark than bite: comparative studies are needed to determine the importance of canine zoonoses in aboriginal communities. a critical review of published research. | the objective of this review was to identify and critique over forty years of peer-reviewed literature concerned with the transmission of canine zoonoses to aboriginal people and determine the zoonotic organisms documented in dogs in australian aboriginal communities. a systematic literature search of public health, medical and veterinary databases identified 19 articles suitable for critical appraisal. thirteen articles documented the occurrence of recognized zoonotic organisms in dogs in abori ... | 2017 | 28342271 |
| small rodents as paratenic or intermediate hosts of carnivore parasites in berlin, germany. | rodents are important intermediate and paratenic hosts for carnivore parasites, including the important zoonotic agents toxoplasma, echinococcus and toxocara. monitoring of such parasites in rodents can be used to detect increasing risks for human and veterinary public health. rodents were trapped at four sites in berlin, two near the city center, two at the periphery. pcrs were conducted to detect coccidia (target its-1) and specifically toxoplasma gondii (repetitive element) in brain and ascar ... | 2017 | 28278269 |
| evaluation of the prevalence and clinical impact of toxocariasis in patients with eosinophilia of unknown origin. | eosinophilia has numerous diverse causes, and in many patients, it is not possible to establish the cause of eosinophilia. recently, toxocariasis was introduced as one cause of eosinophilia. the aims of this study were to evaluate the prevalence of toxocariasis and the clinical impact of albendazole treatment for toxocariasis in patients suspected of eosinophilia of unknown origin. | 2017 | 28352060 |
| tissue distribution and functional analysis of vitellogenin-6 of toxocara canis. | toxocara canis is an common intestinal nematode of canids and the principal causative agent of human toxocariasis. vitellogenin (vg), a source of amino acids and lipids in the eggs, are considered to play an important role in embryo development of a wide range of organisms. in the present study, the transcriptional levels of tc-vit-6 gene in male and female adult t. canis were determined by quantitative real-time pcr, which indicated high transcription of tc-vit-6 in the intestine, reproductive ... | 2017 | 28351684 |
| toxocariasis of the central nervous system: with report of two cases. | toxocariasis is a parasitic infection caused by the roundworms toxocara canis or toxocara cati, mostly due to accidental ingestion of embryonated eggs. clinical manifestations vary and are classified according to the organs affected. central nervous system involvement is an unusual complication. here, we report two cases with neurological manifestations, in which there was cerebrospinal fluid (csf) eosinophilia with marked blood eosinophilia and a positive serology for toxocara both in serum and ... | 2017 | 28157623 |
| distribution and dynamics of soil contamination with toxocara canis and toxocara cati eggs in poland and prevention measures proposed after 20 years of study. | the studies conducted in the years 1994-2013 allowed to determine the distribution of toxocara spp. eggs in the soil of different types of urban and rural areas in poland and to establish seasonal and multi-year dynamics of soil contamination with t. cati and t. canis eggs. out of 3309 soil samples examined, 14.9% contained the eggs and the average density was 3.43 eggs/100g of soil. the level of soil contamination was the highest in cities, lower in villages, and lowest in small towns. in urban ... | 2017 | 28115175 |
| trichoderma virens as a biocontrol of toxocara canis: in vivo evaluation. | microorganisms have been widely studied as biological control agents of parasites of medical and veterinary importance. coprophagous arthropods, bacteria and fungi are among the different organisms evaluated as potential biological control agents. nematophagous fungi capture and digest the free forms of nematodes in the soil. due to its zoonotic potential, toxocara canis have been brought to the attention of researchers. | 2017 | 28109772 |
| seroepidemiological study of toxocariasis in the owners of domestic cats and dogs in mashhad, northeastern iran. | toxocariasis is the clinical terms applied to infection of human with ascarid nematodes in the order ascaridida, named toxocara canis and t. cati. because in recent years in iran many people desire to keep pets (cats and dogs), and lacking of seroepidemiological study of toxocariasis in mashhad, we decided to determine the seroprevalence of toxocariasis among people who own cats and dogs in comparison with control group. | 2017 | 28096863 |
| helminth infections and cardiovascular diseases: toxocara species is contributing to the disease. | toxocariasis is the clinical term used to describe human infection with either the dog ascarid toxocara canis or the feline ascarid toxocara cati. as with other helminths zoonoses, the infective larvae of these toxocara species cannot mature into adults in the human host. instead, the worms wander through organs and tissues, mainly the liver, lungs, myocardium, kidney and central nervous system, in a vain attempt to find that, which they need to mature into adults. the migration of these immatur ... | 2017 | 27492228 |
| influence of land use and meteorological factors on the spatial distribution of toxocara canis and toxocara cati eggs in soil in urban areas. | soil which has been contaminated by toxocara spp. eggs is considered as one of the main infection sources of toxocariasis in animals and humans. the present study conducted a detailed investigation into the spatial patterns of toxocara canis (t. canis) and toxocara cati (t. cati) eggs in soil in urban area of northeastern mainland china, and assessed the inter-relationships between meteorological factors, land use and the distribution of the toxocara spp. eggs. polymerase chain reaction (pcr) wa ... | 2017 | 28043392 |
| seroprevalence and risk factors for toxocara canis infection in serbia during 2015. | we report data on the toxocara seroprevalence evidenced in 2015 from samples of 40 children and 298 adults of the population living in different areas of serbia, and on possible association of certain variables with infection. detection of specific antibodies was performed using an enzyme-linked immunosorbent assay; all ambiguous results and part of the positive and negative sera were further analyzed by confirmatory western blot test. an overall 23.5% seroprevalence was noticed, which was confi ... | 2017 | 27893948 |
| comparative transcriptomic analyses of male and female adult toxocara canis. | toxocariasis is an important, neglected zoonosis caused mainly by toxocara canis. although our knowledge of helminth molecular biology is improving through completed draft genome projects, there is limited detailed information on the molecular biology of toxocara species. here, transcriptomic sequencing of male and female adult t. canis and comparative analyses were conducted. for each sex, two-thirds (66-67%) of quality-filtered reads mapped to the gene set of t. canis, and at least five reads ... | 2017 | 27845205 |
| proteomic analysis of toxocara canis excretory and secretory (tes) proteins. | toxocariasis is a neglected disease, and its main etiological agent is the nematode toxocara canis. serological diagnosis is performed by an enzyme-linked immunosorbent assay using t. canis excretory and secretory (tes) antigens produced by in vitro cultivation of larvae. identification of tes proteins can be useful for the development of new diagnostic strategies since few tes components have been described so far. herein, we report the results obtained by proteomic analysis of tes proteins usi ... | 2017 | 27638150 |
| toxocara canis myelitis involving the lumbosacral region: a case report. | toxocara canis is a parasite known to cause visceral larva migrans. the infection rarely affects the central nervous system but there have been several reports of myelitis caused by visceral larva migrans due to toxocara canis. in previous reported cases, the lesions were located in the thoracic or cervical spinal cord. to the best of our knowledge, this is the first report of a lesion involving the lumbosacral region. | 2017 | 26832660 |
| seroepidemiology of toxocariasis in children (5-15 yr old) referred to the pediatric clinic of imam hossein hospital, isfahan, iran. | human toxocariasis, a helminthozoonosis, is due to the migration of toxocara species larvae into human organisms. humans, especially children become infected by ingesting of embryonated eggs from soil, dirty hands, and raw vegetables. seroprevalence of this infection is high in developed countries, especially in rural areas. the aim of this study was to investigate the seroepidemiology of toxocariasis in children referred to the pediatric clinic of imam hossein hospital, isfahan, iran. | 2017 | 26811731 |
| soil contamination with toxocara spp. eggs in public parks of mashhad and khaf, north east of iran. | toxocariasis is an important disease caused by the larvae of parasitic worms such as toxocara canis and t. cati. public parks can be the source of toxocariasis for small children. this survey was conducted to determine the prevalence of toxocara spp. ova in parks of mashhad and khaf northeastern iran. | 2017 | 26246828 |
| seroprevalence and associated risk factors of toxocariasis among college students in taipei city, taiwan. | infection by toxocara spp. is known to be significantly associated with partial epilepsy. it has become popular for people to raise dogs/cats as pets and consume roasted meat/viscera, and the status of toxocara spp. infection, epilepsy awareness, and associated risk factors among the general population are currently unknown in taiwan. | 2017 | 26622304 |
| seroepidemiological study of toxocariasis among volunteers animal husbandry workers and veterinary in southern anatolia in turkey in 2014. | human toxocariasis is a parasitic infection caused by the larvae of toxocara canis. we examine the toxocara seroprevalance in veterinarians and animal husbandry workers living in the mugla province, turkey to evaluate better the risk factors for toxocara exposure. | 2017 | 26622303 |
| elevated trans-mammary transmission of toxocara canis larvae in balb/c mice. | toxocariasis is a widespread zoonosis and is considered an important worldwide public health problem. the aim of this study was to investigate the frequency of trans-mammary toxocara canis infection in newborn balb/c mice nursed by females experimentally infected with 1,200 eggs after delivery. after 50 days of age, the presence of larvae in different organs of the offspring was investigated. trans-mammary infection was confirmed in 73.9% of the mice that had been nursed by infected females. the ... | 2017 | 25651332 |
| coprodiagnosis of echinococcus granulosus infection in dogs from ankara, turkey. | the present study were undertaken to compare two isolation techniques (centrifugal flotation and sedimentation) for recovering taeniid eggs from faecal samples, to identify e. granulosus dna from taeniid eggs by pcr, and to determine the prevalence of e. granulosus in dogs in villages. faecal samples were collected from 100 dogs in ankara province. taenia spp. eggs were found in 27% of dogs faeces. echinococcus granulosus-specific pcr was obtained in 14 (51.85%) of the taeniid eggs-positive samp ... | 2017 | 28606323 |
| intestinal and external parasites of raccoon dogs (nyctereutes procyonoides) in western poland | parasites of an invasive species, the raccoon dog (nyctereutes procyonoides) from western poland were investigated to clarify poorly known ecological key aspects of the species. the research was conducted in two study areas: the ujście warty national park and the bogdaniec forestry district. intestinal samples were collected from the intestinal tracks of 39 dead animals and 51 faecal samples were collected in all seasons from latrines of raccoon dogs. macro-parasites, their eggs and protozoan pa ... | 2017 | 28601061 |
| road killed carnivores illustrate the status of zoonotic helminthes in caspian sea littoral of iran. | carnivore carcasses on the roads can be regarded as study materials in parasitology and eco-epidemiology. stray carnivores such as dogs and cats are known to harbor so many different pathogens like zoonotic helminthes. the current investigation, apparent the status of the helminthic parasites found in road killed carnivores from different parts of guilan province north of iran. | 2017 | 28761483 |
| enzyme-linked immunosorbent assays for coproantigen detection of ancylostoma caninum and toxocara canis in dogs and toxocara cati in cats. | we report the development and field validation of 2 elisas for the detection of ancylostoma caninum or toxocara canis coproantigens in the feces of dogs with experimental and natural infections, and evidence of cross-reactivity with respective feline counterparts. a. caninum-specific coproantigens were detected in feces of experimentally infected dogs starting at 9 d post-infection (dpi), whereas eggs were not seen until 23 dpi. t. canis-specific coproantigens were detected in 3 of 5 experimenta ... | 2017 | 28424002 |
| treatment of larva migrans syndrome with long-term administration of albendazole. | larva migrans syndrome is a food-borne parasitic disease in humans, caused by accidental ingestion of eggs or larvae of ascarid nematodes, namely, toxocara canis, toxocara cati, or ascaris suum, the roundworms commonly found in the intestines of dogs, cats and pigs respectively. when a patient is diagnosed as having larva migrans syndrome, oral-administration of albendazole is recommended, however, the regimen remains controversial worldwide. in japan, the duration of albendazole administration ... | 2017 | 28754237 |
| molecular characterization and transcriptional analysis of the female-enriched chondroitin proteoglycan 2 of toxocara canis. | toxocara canis is an important but neglected zoonotic parasite, and is the causative agent of human toxocariasis. chondroitin proteoglycans are biological macromolecules, widely distributed in extracellular matrices, with a great diversity of functions in mammals. however, there is limited information regarding chondroitin proteoglycans in nematode parasites. in the present study, a female-enriched chondroitin proteoglycan 2 gene of t. canis (tc-cpg-2) was cloned and characterized. quantitative ... | 2017 | 28434412 |
| invasive forms of canine endoparasites as a potential threat to public health - a review and own studies. | [b]abstract [/b] dogs serve as the vectors of serious zoonotic parasitic diseases. in the month of may 2012 - 2014, 339 dog faeces samples from seven public sites in chełmno, a town in northern poland, were collected and examined to determine the gastrointestinal parasite fauna of dogs. each faecal sample was dissected with a needle, checked for tapeworm segments and examined for parasite eggs and oocysts using the flotation and decantation method and a modified baermann technique. differences w ... | 2017 | 28664702 |
| assessment of u.s. pediatrician knowledge of toxocariasis. | toxocariasis, one of a group of parasitic diseases known as neglected parasitic infections, is a disease caused by the larvae of two species of toxocara roundworms, toxocara canis, from dogs, and less commonly toxocara cati, from cats. although most infected individuals are asymptomatic, clinical manifestations may include fever, fatigue, coughing, wheezing, or abdominal pain (visceral toxocariasis) or vision loss, retina damage, or eye inflammation (ocular toxocariasis). to assess u.s. pediatri ... | 2017 | 28820703 |
| toxocara canis: analysis of the kinetics of antigen release and antibody production in an in vivo model for the detection of past or present infection. | worldwide, toxocara canis is an important zoonotic nematode of public health concern. this soil-transmitted helminth causes visceral larva and ocular larva migrans in paratenic hosts. the detection of t. canis larva migrans is complicated because current immunological tests detect only igg antibodies, which can cross-react with antigens from other parasites and cannot distinguish between the past and present infection. analysis of antigen release and antibody production could help improve the de ... | 2017 | 28807291 |
| epidemiological study of toxocar canis in children under 14-years-old and dogs in zabol and chabahar districts, southeast of iran. | the purpose of this study was seroepidemiological and parasitological assessment of toxocara canis infection in children and dogs in zabol and chabahar, iran. | 2017 | 28761466 |
| the 33.1 kda excretory/secretory protein produced by toxocara canis larvae serves as a potential common biomarker for serodiagnosis of toxocariasis in paratenic animals and human. | toxocariasis is a prevalent zoonosis disease caused by the closely related nematode species toxocara canis and toxocara cati which parasitise canidae and felidae respectively. in paratenic hosts, larvae of these worms cause multiple organ damage. however, how these paratenic hosts response to these worms and whether any common biomarker can be applied for diagnosis are still unclear. | 2017 | 28761463 |
| [toxocariasis, a neglected disease in switzerland ?] | toxocariasis is a zoonotic disease that occurs when humans are infected by the parasites toxocara canis or toxocara cati. toxocariasis is highly prevalent in tropical areas, but can also be found in industrialized countries, particularly in rural areas. clinical presentation can range from asymptomatic infection to more severe disease. diagnosis of toxocariasis is based on suggestive clinical findings, eosinophilia and a positive serological testing. albendazole represents the first-line treatme ... | 2017 | 28727331 |
| loop-mediated isothermal amplification as a reliable assay for toxocara canis infection in pet dogs. | keeping of infected dogs as pet results in the potential transmission risk factors for shedding helminthic infections such as toxocariasis. lack of accurate identification of toxocara canis eggs in non-dewormed infected pet dogs remains a diagnostic concern among researchers. in this study, dog owners were asked to fill up a questionnaire regarding their pets and their attitude towards the deworming regimen. one hundred faecal samples were collected from pet dogs (northwest iran) and were subseq ... | 2017 | 28689247 |
| differentiation of toxocara canis and toxocara cati based on pcr-rflp analyses of rdna-its and mitochondrial cox1 and nad1 regions. | the definitive genetic identification of toxocara species is currently based on pcr/sequencing. the objectives of the present study were to design and conduct an in silico polymerase chain reaction-restriction fragment length polymorphism method for identification of toxocara species. in silico analyses using the dnasis and nebcutter softwares were performed with rdna internal transcribed spacers, and mitochondrial cox1 and nad1 sequences obtained in our previous studies along with relevant sequ ... | 2017 | 28682773 |
| cluster-like headache secondary to focal cervical myelitis. | cluster headache (ch) is characterized by attacks of severe periorbital pain associated with autonomic symptoms. as with other forms of primary headache, structural lesions should be excluded, particularly if the headache presents with an atypical pattern. | 2017 | 28644256 |
| evaluation of the transcription of interleukin-12 in the intestinal mucosa of mice subjected to experimental toxocariasis and supplemented with saccharomyces boulardii. | 2017 | 28606326 | |
| seroepidemiological study and associated risk factors of toxocara canis infection among preschool children in osun state, nigeria. | human toxocariasis is caused by the nematode, toxocara canis and it is a poorly understood phenomenon in nigeria. seroepidemiological studies have not been previously carried out among the preschool aged children in nigeria. a cross-sectional study was conducted in pre-school children in four communities from osun state, nigeria between january and july 2016. a total of 308 children aged 9 months and 5 years were studied comprising 53.2% (164/308) male and 46.8% (144/308) female. blood samples w ... | 2017 | 28591555 |
| environmental contamination with toxocara spp. eggs in public parks and playground sandpits of greater lisbon, portugal. | toxocarosis is a zoonotic parasitic disease transmitted from companion animals to humans. environmental contamination with toxocara eggs is considered to be the main source of human infections. in portugal, knowledge regarding the current situation, including density, distribution and environmental contamination by toxocara spp., is largely unknown. the present study investigated environmental contamination with toxocara spp. eggs, in soil and faecal samples collected from public parks and playg ... | 2017 | 28545900 |
| abnormal neurobehaviour and impaired memory function as a consequence of toxocara canis- as well as toxocara cati-induced neurotoxocarosis. | neuroinvasive larvae of the worldwide occurring zoonotic roundworms toxocara canis and t. cati may induce neurotoxocarosis (nt) in humans, provoking a variety of symptoms including cognitive deficits as well as neurological dysfunctions. an association with neuropsychological disorders has been discussed. similar symptoms have been described in t. canis-infected mice, whereas data on t. cati-induced nt are rare. therefore, it was aimed to obtain insights into the impact on neurobehaviour as well ... | 2017 | 28481889 |
| visceral larva migrans due to toxocara canis in a 9-year-old boy mimicking hepatic hemangiomas. | 2017 | 28470813 | |
| experimental toxocariasis in balb/c mice: relationship between parasite inoculum and the igg immune response. | balb/c mice were inoculated with 5-500 toxocara canis infective eggs, and bled at 15-120 days post infection (dpi) to evaluate the dynamics of igg antibody response and larvae distribution. positive results were observed in all occasions for every inoculum, and a direct proportional relationship between antibody detection and the parasitic load was observed. in samples collected at 60 dpi, detection of igg was more intense, especially with the 50 and 500 egg doses; also, a correlation between an ... | 2017 | 28443979 |
| prevalence of toxocara antibodies among patients clinically suspected to have ocular toxocariasis: a retrospective descriptive study in sri lanka. | human toxocariasis, caused by toxocara canis, t. cati, and t. vitulorum of dogs, cats and ruminants respectively, is recognized as an important zoonotic infection worldwide. the typical clinical syndromes of toxocariasis in humans are ocular larva migrans (olm) and visceral larva migrans (vlm). the most commonly affected sites of olm are the peripheral retina and/or vitreous humor. in sri lanka, there is a dearth of information on prevalence of ocular infection in our population. therefore, the ... | 2017 | 28438141 |
| enteroparasitoses and toxocarosis affecting children from mar del plata city, argentina. | this study evaluated the existence of enteroparasitoses and toxocarosis in children of peripheral (pc) and urban communities (uc) from mar del plata city (argentina) and their associations with socio-environmental conditions. a parasite vulnerability index (pvi) was elaborated using variables such as overcrowding, floor type, drinking water source, wastewater disposal, solid waste disposal, presence of animals and schooling level. the pc evidenced statistically significant higher frequencies of ... | 2017 | 28432449 |
| treatment-resistant neuromyelitis optica spectrum disorders associated with toxocara canis infection: a case report. | a 53-year-old woman was admitted to the department of neurology in tenri hospital because of progressive thoracic myelitis a month after she had eaten uncooked bovine liver. a previous episode of right optic neuritis and a positive test for serum anti-aquaporin-4 antibodies indicated a diagnosis of neuromyelitis optica spectrum disorders. although the patient initially recovered with the reduction of anti-aquaporin-4 antibodies during treatment with intravenous methylprednisolone infusion and pl ... | 2017 | 28427692 |
| [ultrasonographic findings in ocular toxocariasis]. | to evaluate ophthalmic ultrasound findings in the three presentation forms of ocular toxocariasis (peripheral or posterior pole granulomas and chronic endophthalmitis), in patients with confirmed diagnosis of ocular toxocariasis. | 2016 | 22552417 |
| efficacy of nitazoxanide against toxocara canis: larval recovery and humoral immune response in experimentally infected mice. | the efficacy of nitazoxanide (ntz) against toxocariasis was investigated in an experimental murine model and results were compared to those obtained using mebendazole. sixty male balb/c mice, aged six to eight weeks-old, were divided into groups of 10 each; fifty were orally infected with 300 larvaed eggs of t. canis and grouped as follows, g i: infected untreated mice; g ii: infected mice treated with mbz (15 mg/kg/day) 10 days postinfection (dpi); g iii: infected mice treated with ntz (20 mg/k ... | 2016 | 26422159 |
| toxocara malaysiensis infection in domestic cats in vietnam--an emerging zoonotic issue? | toxocara canis of canids is a parasitic nematode (ascaridoid) that infects humans and other hosts, causing different forms of toxocariasis. this species of toxocara appears to be the most important cause of human disease, likely followed by toxocara cati from felids. although some studies from malaysia and china have shown that cats can harbor another congener, t. malaysiensis, no information is available about this parasite for other countries. moreover, the zoonotic potential of this parasite ... | 2016 | 26584512 |
| toxocariasis-associated cardiac diseases--a systematic review of the literature. | toxocariasis, caused by toxocara canis or toxocara catis, is a worldwide occurring parasitic disease, reaching high prevalences especially in tropical and subtropical countries. the clinical presentation can range from asymptomatic seropositivity to life threatenting disease, depending on the organ system involved. cardiac involvement, one of the possible manifestations of human toxocara spp. infection, is rarely reported in case reports. as far as we know, no systematic reviews of clinical pres ... | 2016 | 26571071 |
| larval migration of the ascarid nematode toxocara canis following infection and re-infection in the gerbil meriones unguiculatus. | a morphological and immunohistochemical study of larval migration patterns was performed in gerbils that were infected once (primary infected group) or twice (secondary infected group) with 1500 eggs of toxocara canis. animals from the primary infected and the re-infected group were killed at different times after infection, and larvae were counted in the intestines, liver, lungs and brain. fragments of all organs were formalin fixed and paraffin embedded for histology and immunohistochemistry a ... | 2016 | 26337823 |
| posterior uveitis or wet age-related macular degeneration? case report. | we present the case of a 61-year-old patient without previous ophthalmic or general history, who developed unilateral posterior pole granuloma and was diagnosed with posterior uveitis most likely due to a systemic toxocara canis infection. clinical examination and ancillary investigations showed elements that were also consistent with wet armd, but laboratory tests and successful use of oral anti-helminthic and corticosteroid therapy in decreasing the macular lesion and improving visual acuity, ... | 2016 | 27373119 |
| determination of igg avidity in balb/c mice experimentally infected with toxocara canis. | toxocariasis is a zoonotic disease in that igm titers can remain high for long periods making difficult to determine the stage of the disease. the aim of this study is to investigate the applicability of indirect elisa, associated with urea, to discriminate between the acute and chronic toxocariasis. igg avidity was evaluated in 25 balb/c mice experimentally infected with 1000 toxocara canis eggs. blood samples were collected, and sera treated with 6 m urea and assayed by elisa every two weeks. ... | 2016 | 25271464 |
| toxocara canis: larvicidal activity of fatty acid amides. | considering the therapeutic potential of fatty acid amides, the present study aimed to evaluate their in vitro activity against toxocara canis larvae and their cytotoxicity for the first time. linoleylpyrrolidilamide was the most potent, with a minimal larvicidal concentration (mlc) of 0.05 mg/ml and 27% cytotoxicity against murine peritoneal macrophages c57bl/6 mice, as assessed by the mtt assay. | 2016 | 26783180 |
| [the epidemiological and epizootiological component of toxocariasis foci as an element of the environmental management system (in case of the republic of altai)]. | the epidemiological and epizootiological features of toxocariasis foci were investigated in the republic of altai. the results of coproovoscopic examinations of dogs, those of serological screening for toxocariasis among different age and occupational groups and coniingents at risk for hiv infection, hepatitis b and c, patients with allergic and bronchopulmonary diseases, toxocariasis mortality rates in the republic of altai, and the materials of sanitary and parasitological studies of soil and ... | 2016 | 26720968 |
| in vitro production of toxocara canis excretory-secretory (tes) antigen. | toxocara canis is a widespread gastrointestinal nematode parasite of dogs and cause toxocara larva migrans, an important zoonotic disease in humans on ingestion of infective eggs. toxocarosis is one of the few human parasitic diseases whose serodiagnosis uses a standardized antigen, t. canis excretory secretory antigen (tes). the present study describes collection of t. canis adult worm, collection and embryonation of t. canis eggs, hatching and separation of t. canis larvae, in vitro maintenanc ... | 2016 | 27605834 |
| the occurrence of toxocara species in naturally infected broiler chickens revealed by molecular approaches. | consuming raw and undercooked meat is known to enhance the risk of human toxocariasis because toxocara species have a wide range of paratenic hosts, including chickens. the aim of this study was to identify species of toxocara in naturally infected broiler chickens using molecular approaches. a polymerase chain reaction (pcr) method was used for the differentiation of toxocara canis and toxocara cati larvae recovered from tissues and organs, and identified by microscopic observations. thirty-thr ... | 2016 | 27571878 |
| [transverse myelitis associated with toxocariasis and the importance of locally produced antibodies for diagnosis]. | toxocariasis caused by toxocara canis or less frequently by t.catis is a common parasitic infection worldwide. clinical spectrum in humans can vary from asymptomatic infection to serious organ disfunction depending on the load of parasite, migration target of the larva and the inflammatory response of the host. transverse myelitis (tm) due to toxocariasis is an uncommon illness identified mainly as case reports in literature. in this report, a case of tm who was diagnosed as neurotoxocariasis by ... | 2016 | 27525404 |
| flotation and adherence characteristics of toxocara canis and t. cati and a reliable method for recovering toxocara eggs from soil. | toxocara canis and t. cati are worldwide distributed intestinal nematodes of canids and felids and pose a threat to public health due to possible clinical manifestations in humans. different methods for detection of toxocara eggs in soil have been described, but conducted studies deal with egg recovery rates of t. canis or "toxocara spp." only whereas t. cati egg recovery has not been taken into consideration. thus, flotation properties in sodium chloride solution and adherence characteristics t ... | 2016 | 27523935 |
| kinetic and avidity of igy anti-toxocara antibodies in experimentally infected chickens. | toxocariasis is a geohelminth zoonosis with worldwide distribution, mainly transmitted through the ingestion of embryonated eggs of nematodes of the toxocara genus. the disease can also be transmitted to humans as a result of eating raw or undercooked meat of paratenic hosts, such as chickens. here, we standardized an enzyme-linked immunosorbent assay (elisa) for evaluating experimentally the kinetic and avidity index (ai) of igy in broiler chickens infected with different doses of toxocara cani ... | 2016 | 27746165 |
| [ocular toxocariasis in a boy with idiopathic nephrotic syndrome - a case report]. | toxocariasis is a common zoonosis caused by infection with toxocara canis or cati larvae. ocular toxocariasis is one of the forms of infestation found in 1/1,000 - 1/10,000 children. children with idiopathic nephrotic syndrome (ins) are at high risk of infections, also parasitic infestations, which can, in turn, cause relapses of the disease. | 2016 | 27760094 |
| recurrent patent infections with toxocara canis in household dogs older than six months: a prospective study. | to reduce environmental contamination with toxocara canis eggs, the current general advice is to deworm all dogs older than six months on average four times a year. however, only a small proportion of non-juvenile household dogs actually shed t. canis eggs, and some dogs shed eggs more frequently than others. the identification of these frequent shedders and the associated risk factors is an important cornerstone for constructing evidence-based deworming regimens. the purpose of this study is to ... | 2016 | 27716389 |
| human toxocariasis: prevalence and factors associated with biosafety in research laboratories. | human toxocariasis is a neglected parasitic disease worldwide. researchers studying this disease use infectious strains of toxocara for experiments. health workers are at risk in the course of their daily routine and must adhere to biosafety standards while carrying out the activities. researchers on biosafety concerning working with these parasites are insufficient. the aim of this study was to determine the rate of seroprevalence of toxocara species among health-care research laboratory worker ... | 2016 | 27698276 |
| frequency of anti- toxocara spp. antibodies in individuals attended by the centro de salud familiar and environmental contamination with toxocara canis eggs in dog feces, in the coastal niebla town, chile. | the frequency of anti-toxocara spp. antibodies in individuals attended by the centro de salud familiar in the coastal niebla town, chile, was related to the host and to environmental factors. igg anti- toxocara antibodies were detected with a commercial elisa kit (scimedx corporation, usa). samples with undetermined absorbance values were subjected to an additional elisa standardized by the instituto de salud pública, chilean health ministry, a commercial elisa (novatec, germany), and a commerci ... | 2016 | 27680167 |
| flotation of toxocara canis eggs in commercial bleach and effects of bleach treatment times on larval development in these eggs. | toxocara canis is a common intestinal nematode of young dogs. puppies contaminate the environment with large numbers of eggs that can embryonate and become infective in less than a month. embryonated eggs are infectious for humans and other paratenic hosts. most t. canis infections in humans are asymptomatic, however, migration of t. canis larvae in the eye and in the central nervous system can result in vision loss, blindness, and even death. the eggs of t. canis are highly resistant to harsh e ... | 2016 | 27874323 |
| detection of specific antibody reactivity to toxocara larval excretory-secretory antigens in asthmatic patients (5-15 years). | humans act as an intermediate host for toxocara canis and toxocara cati. toxocara may be an important risk factor for asthma in humans. the aim of the present study was to evaluate immunoglobulin g (igg) anti-toxocara canis antibody, using enzyme-linked immunosorbent assay (elisa) in asthmatic patients (aged 5-15 years), referring to a clinic of pulmonary diseases in arak, iran. | 2016 | 27857820 |
| occurrences of gastrointestinal parasites in fecal samples from domestic dogs in são paulo, sp, brazil. | occurrences of gastrointestinal parasites were assessed in fecal samples from 3,099 dogs in the metropolitan region of são paulo, sp, that were treated at the veterinary hospital of the university of são paulo veterinary school. the samples were analyzed using the flotation and centrifugal sedimentation methods. the results were compared with those from previous studies (at different times). the frequency of each parasite was correlated with the dogs' ages, breeds and gender, as well as the occu ... | 2016 | 27925072 |
| clinical characteristics and progression of liver abscess caused by toxocara. | to evaluate the clinical characteristics and progression of liver abscess caused by toxocara. | 2016 | 27366302 |
| toxocara canis-associated myelitis with eosinophilic pneumonia. | the existence of toxocara canis-specific antibodies has recently been reported in patients with atopic myelitis. here, we report the case of a 35-year-old male patient admitted with a chief complaint of right lower limb hypoesthesia lasting for a month. the patient was diagnosed with eosinophilic pneumonia 3 months ago, and a spine mri revealed the presence of myelitis in the cervicothoracic cord. after confirming the presence of hyper-ige-emia and toxocara canis antibodies, the patient was trea ... | 2016 | 27358582 |
| cap protein superfamily members in toxocara canis. | proteins of the cysteine-rich secretory proteins, antigen 5 and pathogenesis-related 1 (cap) superfamily are recognized or proposed to play roles in parasite development and reproduction, and in modulating host immune attack and infection processes. however, little is known about these proteins for most parasites. | 2016 | 27342979 |
| seroepidemiological investigation of toxocara canis in a female greek pregnant population in the area of athens. | the purpose of this study was to investigate the of areas where the soil is contaminated by toxocara ova and also to assess seroepidemiological positivity in a greek pregnant women population (elisa igg test). | 2016 | 27328496 |
| the in vitro effect of prolactin on the growth, motility and expression of prolactin receptors in larvae of toxocara canis. | the in vitro effect of prolactin (prl) on the growth and motility of toxocara canis larvae was assessed. additionally, the expression and location of prolactin receptors (prl-rs) were determined in the larvae. larvae of t. canis were incubated with different concentrations of prl for different periods of time. the stimulated larvae accelerated their enlargement and increased their motility. the mean percentage of prl-r+ cells in non-stimulated larvae, measured by flow cytometry was 7.3±0.3%. com ... | 2016 | 27270387 |
| chronic polyarthritis as isolated manifestation of toxocariasis. | human toxocariasis is a parasitic zoonosis mainly caused by toxocara canis or toxocara cati and is acquired by ingestion of the parasite's embryonated eggs. arthralgia and/or arthritis were reported in up to 17% of the cases, generally with acute duration (less than 6 weeks). however, to our knowledge, chronic polyarthritis, as the isolated presentation of toxocara infection, was not reported. one of the 5809 patients that was followed up at our service (0.017%) had chronic polyarthritis as the ... | 2016 | 27267534 |
| clinical case of the month: hypereosinophilia in a young woman with a history of childhood asthma. | hypereosinophillia is a rare clinical entity. it is associated with a wide differential diagnosis including neoplasm, infection, and allergic etiologies. clinicians should have a well defined approach to hypereosinophilia in order to find treatable causes. we present a case of hypereosinophillia caused by parasitic infection with toxocara canis. we also review epidemiology, transmission, microbiology, and management of toxocara canis. | 2016 | 27159518 |
| eosinophilic myocarditis due to toxocariasis: not a rare cause. | myocarditis is a clinically important disease because of the high mortality. from the perspective of treatment strategy, eosinophilic myocarditis should be distinguished from other types of myocarditis. toxocariasis, caused by toxocara canis or toxocara cati, is known as a cause of eosinophilic myocarditis but is considered rare. as it is an unpopular disease, eosinophilic myocarditis due to toxocariasis may be underdiagnosed. we experienced two cases of eosinophilic myocarditis due to toxocaria ... | 2016 | 27123346 |
| micrornas of toxocara canis and their predicted functional roles. | toxocara canis is the causative agent of toxocariasis of humans and other animals. this parasitic nematode (roundworm) has a complex life cycle, in which substantial developmental changes and switches occur. as small non-coding rnas (srnas) are key regulators of gene expression in a wide range of organisms, we explored these rnas in t. canis to provide a basis for future studies of its developmental biology as well as host interactions and disease at the molecular level. | 2016 | 27108220 |
| toxocariasis and childhood asthma: a case-control study. | the objective of this study is to investigate the association between anti-toxocara igg seropositivity and asthma in children. | 2016 | 27104477 |
| toxocara canis and chronic urticaria. | no abstract. | 2016 | 27090371 |
| risk factors for toxocara spp. seroprevalence and its association with atopy and asthma phenotypes in school-age children in a small town and semi-rural areas of northeast brazil. | toxocara canis, toxocara cati, are roundworms that live in the intestines of dogs and cats, respectively, and are predominantly agents of human toxocariasis. studies have suggested that toxocara spp. seroprevalence increases levels of total and aeroallergen-specific ige (sige), asthma prevalence and asthma morbidity. nevertheless, other work reported a negative association between toxocara spp. seropositivity with skin hypersensititity and a positive association with sige. the objective of the p ... | 2016 | 27080332 |
| kinetics and avidity of anti-toxocara antibodies (igg) in rabbits experimentally infected with toxocara canis. | an evaluation was made of the kinetics and avidity of anti-toxocara antibodies (igg) in rabbits experimentally infected with embryonated toxocara canis eggs. seventeen four month old new zealand white rabbits were distributed into two groups. in the experimental group, twelve rabbits were infected orally with 1,000 embryonated t. canis eggs. a second group (n = 5), uninfected, was used as a control. serum samples were collected for analysis on days 7, 14, 21, 28 and 60 post-infection (dpi). an i ... | 2016 | 27027550 |
| harnessing the toxocara genome to underpin toxocariasis research and new interventions. | parasitic worms, such as flatworms (platyhelminths) and roundworms (nematodes), cause substantial morbidity and mortality in animals and people globally. the ascaridoid nematode toxocara canis is a zoonotic parasite of socioeconomic significance worldwide. in humans, this worm causes toxocariasis (disease) mainly in underprivileged communities in both the developed and developing worlds. while reasonably well studied from clinical and epidemiological perspectives, little is understood about the ... | 2016 | 27015948 |
| prevalence of helminths in dogs and owners' awareness of zoonotic diseases in mampong, ashanti, ghana. | dogs are popular pets that live closely with humans. however, this cohabitation allows for the transmission of zoonotic parasites to humans. in ghana, very little is known about zoonotic parasites in dogs. we examined excrements of 154 dogs for intestinal helminthes using saturated sodium chloride as a floatation medium and further interviewed 100 dog owners regarding knowledge on zoonosis and pet management practices. thirteen parasite species were identified, with an overall prevalence of 52.6 ... | 2016 | 26941994 |
| evaluation of the goldmann-witmer coefficient in the immunological diagnosis of ocular toxocariasis. | ocular toxocariasis (ot) is a zoonotic parasitic infection mainly caused by the intraocular tissue invasion of second-stage toxocara canis or toxocara cati larva. measuring specific anti-t. canis antibodies in the intraocular fluid (if) can increase ot diagnosis accuracy using goldmann-witmer coefficient (gwc). however, there is no systemic evaluation of gwc application in the immunological diagnosis of ot. to assess gwc for the immunodiagnosis of ocular toxocariasis, paired if and serum samples ... | 2016 | 26899678 |
| evaluation of a di-o-methylated glycan as a potential antigenic target for the serodiagnosis of human toxocariasis. | serodiagnosis of human toxocariasis is based on the detection of specific igg antibodies by the enzyme-linked immunosorbent assay (elisa) using toxocara larvae excretory-secretory (tes) antigens, but its production is a laborious and time-consuming process being also limited by the availability of adult females of t. canis as source for ova to obtain larvae. chemical synthesis of the di-o-methylated (dim) glycan structure found in the tes antigens has provided material for studying the antibody ... | 2016 | 26896376 |
| toxocara canis: anthelmintic activity of quinone derivatives in murine toxocarosis. | human toxocarosis is a chronic tissue parasitosis most often caused by toxocara canis. the seroprevalence can reach up to 50%, especially among children and adolescents. the anthelmintics used in the treatment have moderate efficacy. the aim of this study was to evaluate the in vitro and in vivo anthelmintic activity of quinones and their derivatives against t. canis larvae and the cytotoxicity of the larvicidal compounds. the compounds were evaluated at 1 mg ml(-1) concentration in microculture ... | 2016 | 26887285 |
| genetic variability and discrimination of low doses of toxocara spp. from public areas soil inferred by loop-mediated isothermal amplification assay as a field-friendly molecular tool. | aim: one of the main diagnostic problems of conventional polymerase chain reaction (pcr) is indiscrimination of low parasitic loads in soil samples. the aim of this study is to determine the genetic diversity and identification of toxocara spp. from public areas soil inferred by loop-mediated isothermal amplification (lamp) assay. | 2016 | 28096624 |
| draft genome of toxocara canis, a pathogen responsible for visceral larva migrans. | this study aimed at constructing a draft genome of the adult female worm toxocara canis using next-generation sequencing (ngs) and de novo assembly, as well as to find new genes after annotation using functional genomics tools. using an ngs machine, we produced dna read data of t. canis. the de novo assembly of the read data was performed using soapdenovo. rna read data were assembled using trinity. structural annotation, homology search, functional annotation, classification of protein domains, ... | 2016 | 28095660 |
| evidence of morphine like substance and μ-opioid receptor expression in toxacara canis (nematoda: ascaridae). | toxocara canis (nematoda: ascaridae) is an intestinal nematode parasite of dogs, which can also cause disease in humans. transmission to humans usually occurs because of direct contact with t. canis eggs present in soil contaminated with the feces of infected dogs. this nematode has extraordinary abilities to survive for many years in different tissues of vertebrates, and develop to maturity in the intestinal tract of its definitive host. survival of parasitic nematodes within a host requires im ... | 2016 | 28144426 |
| characterization and differential expression analysis of toxocara canis aquaporin-1 gene. | toxocara canis is an intestinal nematode of canids with a worldwide distribution, causing an important but neglected parasitic zoonosis in humans. aquaporins (aqp) are a family of water channel proteins, which function as membrane channels to regulate water homeostasis. in this study, the coding sequence of aquaporin-1 gene of t. canis (tc-aqp-1) was cloned and characterized. the obtained tc-aqp-1 coding sequence was 933 bp in length, which predicted to encode 311 amino acids. two conserved aspa ... | 2016 | 27215210 |
| toxocara canis glycans influence antigen recognition by mouse igg1 and igm antibodies. | the impact of sugar moieties of toxocara canis glycoprotein antigens on their recognition by infected mouse antibodies was investigated in this study. native tes and recombinant toxocara mucins generated in pichia pastoris yeast as well as their deglycosylated forms were used in elisa. tes and recombinant mucins were equally recognized by t. canis infected mouse igg1 antibodies. igm immunoglobulins predominantly recognized tes antigens. among mucins recognition of tc-muc-4 was the most significa ... | 2016 | 26751891 |
| modulation of il-12 and ifnγ by probiotic supplementation promotes protection against toxocara canis infection in mice. | in this study, supplementation with the probiotic saccharomyces boulardii promoted a reduction in intensity of infection by toxocara canis and modulates cytokines mrna expression in experimentally infected mice. il-12 gene transcription had 40-fold increase in s. boulardii supplemented uninfected mice and sevenfold increase in supplemented infected mice comparing with not supplemented group. regarding ifnγ, similar results were observed, since probiotic supplementation induced approximately 43-f ... | 2016 | 26971490 |
| the prevalence of intestinal nematodes in cats and dogs from lancashire, north-west england. | to estimate prevalence of clinically-relevant intestinal nematodes in uk cats and dogs using the sensitive faecal analysis technique flotac. | 2016 | 27071856 |
| staphylococcus aureus endocarditis as a complication of toxocariasis-associated endomyocarditis with fibrosis: a case report. | complications associated with toxocara canis infection are rare. we present a case of a patient with staphylococcus aureus endocarditis as a complication of an endomyocardial fibrosis caused by t canis. the epidemiological, pathological, and clinical features of this rare complication are described here. | 2016 | 27800525 |
| a field survey on parasites and antibodies against selected pathogens in owned dogs in lilongwe, malawi. | the aim of this study was to screen for selected parasites and antibody levels against vectorborne pathogens in owned dogs in lilongwe, malawi. the study population consisted of 100 dogs; 80 participating in vaccination-spaying campaigns and 20 visiting a veterinary clinic as paying clients. all dogs went through a general physical examination including visual examination for signs of ectoparasites. a total of 100 blood samples were analysed using commercial snap tests and 40 faecal samples by e ... | 2016 | 27543039 |
| gray fox (urocyon cinereoargenteus) parasite diversity in central mexico. | mexico has a long history of parasitological studies in communities of vertebrates. however, the mega diversity of the country makes fauna inventories an ongoing priority. presently, there is little published on the parasite fauna of gray foxes (urocyon cinereoargenteus schereber, 1775) and this study provides new records of parasites for gray foxes in central mexico. it is a continuation of a series of previous parasitological studies conducted with this carnivore in mexico from 2003 to the pre ... | 2016 | 27408801 |
| arginine kinase in toxocara canis: exon-intron organization, functional analysis of site-directed mutants and evaluation of putative enzyme inhibitors. | to determine exon/intron organization of the toxocara canis (t. canis) ak (tcak) and to test green and black tea and several other chemicals against the activity of recombinant tcak in the guanidino-specific region by site-directed mutants. | 2016 | 27794395 |
| production and evaluation of the recombinant antigen tes-30 of toxocara canis for the immunodiagnosis of toxocariasis. | toxocara canis is a pathogenic nematode of canines which can be accidentally transmitted to humans. although serology is the most important diagnostic tool for this zoonosis, diagnostic kits use crude excretion/secretion antigens, most of them being glycoproteins which are not species-specific and may cross-react with antibodies generated against other parasites. | 2016 | 27622437 |