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antibacterial and antiadhesive activities of extracts from edible plants against soft drink spoilage by asaia spp.this study was conducted to investigate the antibacterial and antiadhesive activities of ethanol extracts from five edible plant parts: cinnamon bark ( cinnamomum zeylanicum ), licorice root ( glycyrrhiza radix ), nettle leaves ( urtica dioica ), green tea leaves ( camellia sinensis ), and elderberry flowers ( sambucus nigra ). the chemical constituents of the extracts were identified using high-performance liquid chromatography and liquid chromatography plus mass spectrometry. six strains of as ...201728221885
five herbs plus thiamine reduce pain and improve functional mobility in patients with pain: a pilot study.context • five herbs-urtica dioica (stinging nettle), boswellia serrata, equisetum arvense, allium sativum, and apium graveolens-have been demonstrated to have activity at several anti-inflammatory pathways and have analgesic properties that are effective in treating chronic musculoskeletal pain. objectives • the study intended to evaluate the clinical efficacy of a proprietary blend of u dioica, b serrata, e arvense, a sativum, a graveolens, and thiamine (vitamin b1), or "the blend," in the tre ...201728160759
factors influencing the distribution and activity of dermacentor reticulatus (f.) ticks in an anthropopressure-unaffected area in central-eastern poland.despite the increasing prevalence and significant role of d. reticulatus in pathogen transmission, the factors influencing its distribution and activity are still poorly known. the paper presents for the first time a study of the d. reticulatus ecology in a protected area, in which the dependence of d. reticulatus occurrence and activity on the ecological habitat type is analysed.201627294631
antioxidant activity and nutritional assessment of under-utilized medicinal plants.the present study investigates the nutritive and anti-nutritive composition of six species (allium porrum, amaranthus spinosis, apium graveolens, caralluma edulis, chenopodium album, urtica dioica). the studied species contained considerable amount of crude protein (4.53-11.41%), crude fat (1.25-3.74%), vitamin c (7.85-28.09mg 100(-1) g) and β-carotene (18.29-169.33mg 100(-1)g). the mineral profile of chenopodium album is considered as potential source of zn (14.51±1.14mg 100-1g), mn (67.71±0.85 ...201628375121
categorization of cathartic (purgative) medicines mentioned in tpm resources according to their specific function.according to traditional persian medicine (tpm) resources, the human digestive system includes four steps. in the first step, gastric digestion, the ingested food pours into the stomach and changes into the leachate called chylous due to the heat produced in the stomach. in the second step, hepatic digestion, the chylous enters in the liver through mesenteric vessels and transforms into the quadruple humors, sanguine, phlegm, bile and black bile due to the liver heat. in the case of humor predom ...201627840491
categorization of cathartic (purgative) medicines mentioned in tpm resources according to their specific function.according to traditional persian medicine (tpm) resources, the human digestive system includes four steps. in the first step, gastric digestion, the ingested food pours into the stomach and changes into the leachate called chylous due to the heat produced in the stomach. in the second step, hepatic digestion, the chylous enters in the liver through mesenteric vessels and transforms into the quadruple humors, sanguine, phlegm, bile and black bile due to the liver heat. in the case of humor predom ...201627516658
chitosan films incorporated with nettle (urtica dioica l.) extract-loaded nanoliposomes: i. physicochemical characterisation and antimicrobial properties.the objective of this study was to characterise and compare physical, mechanical and antimicrobial properties of chitosan-based films, containing free or nanoencapsulated nettle (urtica dioica l.) extract (ne) at concentrations of 0, 0.5, 1 and 1.5% w/w. nanoliposomes were prepared using soy-lecithin by thin-film hydration and sonication method to generate an average size of 107-136 nm with 70% encapsulation efficiency. the information on ft-ir reflected that some new interaction have occurred b ...201627424771
exposure of trypanosoma brucei to an n-acetylglucosamine-binding lectin induces vsg switching and glycosylation defects resulting in reduced infectivity.trypanosoma brucei variant surface glycoproteins (vsg) are glycosylated by both paucimannose and oligomannose structures which are involved in the formation of a protective barrier against the immune system. here, we report that the stinging nettle lectin (uda), with predominant n-acetylglucosamine-binding specificity, interacts with glycosylated vsgs and kills parasites by provoking defects in endocytosis together with impaired cytokinesis. prolonged exposure to uda induced parasite resistance ...201525746926
[investigation of metal element content of some european and far eastern herbs].metal elements and their excess intake have significant influence on general health.201526211750
a cross-cultural comparison of folk plant uses among albanians, bosniaks, gorani and turks living in south kosovo.kosovo represents a unique hotspot of biological and cultural diversity in europe, which allows for interesting cross-cultural ethnobotanical studies. the aims of this study were twofold: 1) to document the state of traditional knowledge related to local (esp. wild) plant uses for food, medicine, and handicrafts in south kosovo; and 2) to examine how communities of different ethnic groups in the region (albanians, bosniaks/gorani, and turks) relate to and value wild botanical taxa in their ecosy ...201525964167
some popular medicinal plants and diseases of the upper palaeolithic in western georgia.palynological studies of cultural layers of cave sediments have been used in order to better understand traditional practices. the upper palaeolithic in georgia (36,000-11,000 cal. bp) provides a rich source of such material. however, up to day from such sediments the identification of medicinal plants has hardly been achieved. large quantities of pollen most notably from entomophilous taxa in fossil spectra can serve as a tool to identify traditionally important species. as these plants are use ...201525769538
nictaba and uda, two glcnac-binding lectins with unique antiviral activity profiles.this study aimed to assess the antiviral properties of a unique lectin (nictaba) produced by the tobacco plant, nicotiana tabacum.201525700718
effects of dietary administration of stinging nettle (urtica dioica) on the growth performance, biochemical, hematological and immunological parameters in juvenile and adult victoria labeo (labeo victorianus) challenged with aeromonas hydrophila.we investigated effects of dietary administration of stinging nettle (urtica dioica) on growth performance, biochemical, hematological and immunological parameters in juvenile and adult victoria labeo (labeo victorianus) against aeromonas hydrophila. fish were divided into 4 groups and fed for 4 and 16 weeks with 0%, 1%, 2% and 5% of u. dioica incorporated into the diet. use of u. dioica in the diet resulted in improved biochemical, hematological and immunological parameters. among the biochemic ...201525827627
genetic variability of stolbur phytoplasma in hyalesthes obsoletus (hemiptera: cixiidae) and its main host plants in vineyard agroecosystems.bois noir is an economically important grapevine yellows that is induced by 'candidatus phytoplasma solani' and principally vectored by the planthopper hyalesthes obsoletus signoret (hemiptera: cixiidae). this study explores the 'ca. p. solani' genetic variability associated to the nettle-h. obsoletus and bindweed-h. obsoletus systems in vineyard agroecosystems of the central-eastern italy. molecular characterization of 'ca. p. solani' isolates was carried out using polymerase chain reaction/res ...201526470289
detection of pyrrolizidine alkaloids in german licensed herbal medicinal teas.because of the hepatotoxic, mutagenic, and cancerogenic effects of pyrrolizidine alkaloids (pas) the german federal institute for risk assessment (bfr) recommends not to exceed a daily pa intake of 0.007 µg/kg body weight (0.42 µg/60 kg adult). in a recent study conducted by the bfr, up to 5647 µg pa/kg dried herbal material were detected in tea products marketed as food.201526055130
inhibition of cytosolic phospholipase a2α (cpla2α) by medicinal plants in relation to their phenolic content.the cytosolic phospholipase a2α(cpla2α) is one of the potential targets for anti-inflammatory drugs, since this enzyme plays a key role in the inflammation processes seen in health disorders, like asthma, allergic reactions, arthritis and neuronal diseases. in this study, cpla2α inhibition by 43 methanol extracts from medicinal plants rich in polyphenols was determined. the eight most active extracts were derived from ribes nigrum (ic50 of 27.7 μg/ml), ononis spinosa (ic50 of 39.4 μg/ml), urtica ...201526287155
medicinal plants traditionally used in the northwest of the basque country (biscay and alava), iberian peninsula.many ethnobotanical studies show that people in industrial countries still rely on their traditional knowledge of medicinal plants for self-treatment, although the trend might not be as common as some decades ago. given the social and public health implications of ethnopharmacological practices, this survey aims at recording and analysing the medicinal plants used in the folk medicine of the northwest of the basque country focusing on how medicinal plants knowledge and practices evolve.201424389558
predicting as, cd, cu, pb and zn levels in grasses (agrostis sp. and poa sp.) and stinging nettle (urtica dioica) applying soil-plant transfer models.the aim of this study was to derive regression-based soil-plant models to predict and compare metal(loid) (i.e. as, cd, cu, pb and zn) concentrations in plants (grass agrostis sp./poa sp. and nettle urtica dioica l.) among sites with a wide range of metal pollution and a wide variation in soil properties. regression models were based on the pseudo total (aqua-regia) and exchangeable (0.01 m cacl2) soil metal concentrations. plant metal concentrations were best explained by the pseudo total soil ...201425000582
phytotherapy of benign prostatic hyperplasia. a minireview.benign prostate hyperplasia (bph) is a common condition affecting older men, with an incidence that is age-dependent. histological bph, which typically develops after the age of 40 years, ranges in prevalence from >50% at 60 years to as high as 90% by 85 years of age. typical symptoms include increased frequency of urination, nocturia, urgency, hesitancy, and weak urine stream. conventional medicines used for the treatment of bph include alpha blockers and 5-alpha reductase inhibitors. this arti ...201425165780
traditional knowledge on poisonous plants of udhampur district of jammu and kashmir, india.poisonous plants comprise the third largest category of poisons known around the world. other than affecting the humans directly, they are the major cause of economic losses in the livestock industry since the advent of civilisation. aim of the present study was to collect and systematically document the traditional knowledge of poisonous plants of udhampur district for the benefit of humanity before it is entombed forever.201424412380
an abundant 'candidatus phytoplasma solani' tuf b strain is associated with grapevine, stinging nettle and hyalesthes obsoletus.bois noir (bn) associated with 'candidatus phytoplasma solani' (stolbur) is regularly found in austrian vine growing regions. investigations between 2003 and 2008 indicated sporadic presence of the confirmed disease vector hyalesthes obsoletus and frequent infections of bindweed and grapevine. infections of nettles were rare. in contrast present investigations revealed a mass occurrence of h. obsoletus almost exclusively on stinging nettle. the high population densities of h. obsoletus on urtica ...201425309042
evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens.this study demonstrates 5α-reductase inhibitory activity of certain herbs useful in the management of androgenic disorders. ganoderma lucidum (curtis) p. karst (gl), urtica dioica linn. (ud), caesalpinia bonducella fleming. (cb), tribulus terrestris linn. (tt), pedalium murex linn. (pm), sphaeranthus indicus linn. (si), cuscuta reflexa roxb. (cr), citrullus colocynthis schrad. (cc), benincasa hispida cogn. (bh), phyllanthus niruri linn. (pn) and echinops echinatus linn. (ee) were included in the ...201423710567
ethnoveterinary herbal remedies used by farmers in four north-eastern swiss cantons (st. gallen, thurgau, appenzell innerrhoden and appenzell ausserrhoden).very few ethnoveterinary surveys have been conducted in central europe. however, traditional knowledge on the use of medicinal plants might be an option for future concepts in treatment of livestock diseases. therefore the aim of this study was to document and analyse the traditional knowledge and use of homemade herbal remedies for livestock by farmers in four swiss cantons.201424685062
microtubules in root hairs.the microtubules of root hairs of raphanus sativus, lepidium sativum, equisetum hyemale, limnobium stoloniferum, ceratopteris thalictroides, allium sativum and urtica dioica were investigated using immunofluorescence and electron microscopy. arrays of cortical microtubules were observed in all hairs. the microtubules in the hairs show net axial orientations, but in allium and urtica helical microtubule patterns are also present. numerical parameters of microtubules in raphanus, equisetum and lim ...20144066793
medicinal plant extracts can variously modify biofilm formation in escherichia coli.low concentrations of black tea and water extracts from medicinal plants arctostaphylos uva-ursi, vaccinium vitis-idaea, tilia cordata, betula pendula and zea mays stimulated biofilm formation in escherichia coli bw25113 up to three times. similar effect was observed for tannic acid and low concentrations of quercetin. in contrast, the extract from urtica dioica reduced biofilm production. pretreatment with plant extracts variously modified antibiotic effects on specific biofilm formation (sbf). ...201424500005
introducing urtica dioica, a native plant of khuzestan, as an antibacterial medicinal plant.urtica dioica is a flowering plant with long history of use in folk medicine and as a food source.201425625045
levels of some microelements and essential heavy metals in herbal teas in serbia.levels of fe, mn, cu, zn, mo, co, ni, se, sn and al were determined in 14 medicinal plants from serbia, which are widely used in phytopharmacy as herbal teas. the following plants were investigated: yarrow (achillea millefolium l.), basil (ocimum hasilicum l.), st. john's wort (hypericum perforatum l.), peppermint (mentha x piperita l.), field horsetail (equisetum arvense l.), stinging nettle (urtica dioica l.), thyme (thymus serpyllum l.), maize silk (zea mays l. - maydis stigma), hibiscus (hib ...201425265817
antimicrobial activity of methanolic extracts of sambucus ebulus and urtica dioica against clinical isolates of methicillin resistant staphylococcus aureus.increase in the emergence of drug -resistant pathogens led to the development of natural antimicrobials. in this study the antimicrobial effect of methanolic extracts of sambucus ebulus and urtica dioica on 16 skin and wound infections isolates of methicillin resistant s. aureus have been studied.201425395702
combining site occupancy, breeding population sizes and reproductive success to calculate time-averaged reproductive output of different habitat types: an application to tricolored blackbirds.in metapopulations in which habitat patches vary in quality and occupancy it can be complicated to calculate the net time-averaged contribution to reproduction of particular populations. surprisingly, few indices have been proposed for this purpose. we combined occupancy, abundance, frequency of occurrence, and reproductive success to determine the net value of different sites through time and applied this method to a bird of conservation concern. the tricolored blackbird (agelaius tricolor) has ...201424817307
in vitro evaluations of cytotoxicity of eight antidiabetic medicinal plants and their effect on glut4 translocation.despite the enormous achievements in conventional medicine, herbal-based medicines are still a common practice for the treatment of diabetes. trigonella foenum-graecum, atriplex halimus, olea europaea, urtica dioica, allium sativum, allium cepa, nigella sativa, and cinnamomum cassia are strongly recommended in the greco-arab and islamic medicine for the treatment and prevention of diabetes. cytotoxicity (mtt and ldh assays) of the plant extracts was assessed using cells from the liver hepatocell ...201323606883
anti-mycobacterial screening of five indian medicinal plants and partial purification of active extracts of cassia sophera and urtica dioica.to find out the anti-mycobacterial potential of cassia sophera (c. sophera), urtica dioica (u. dioica), momordica dioica, tribulus terrestris and coccinia indica plants against multi-drug resistant (mdr) strain of mycobacterium tuberculosis (m. tuberculosis).201323608375
[in vitro effect of ankaferd blood stopper®, a plant extract against mycobacterium tuberculosis isolates].treatment of drug-resistant mycobacterium tuberculosis infections requires combination of anti-tuberculosis drugs which have several toxic side effects. thus there is a need for safer and effective new drugs. ankaferd blood stopper® (abs), which is a mixture of plant extracts prepared from alpinia officinarum, glycyrrhiza glabra, thymus vulgaris, urtica dioica and vitis vinifera, has homeostatic and antibacterial effects. standard solutions of abs are already being used topically for post-trauma ...201323390904
where does the border lie: locally grown plants used for making tea for recreation and/or healing, 1970s-1990s estonia.traditional use of local wild and cultivated plants for making recreational tea in estonia often borders with the medicinal use of the same plants.201323994468
water-extractable magnesium, manganese and copper in leaves and herbs of medicinal plants.since herbal teas, infusions and decoctions prepared from medicinal plants are popular remedies, it remains a topical question whether these herbal drugs can be treated as sources of essential elements for humans, who often use them in their everyday diet. therefore, total and water-extractable contents of mg, mn and cu were determined in 41 leaves originating from four botanical species of plantago lanceolata, arctostaphyllos uva-ursi, rubus fruticosus and betula sp., as well as in 33 samples o ...201322574504
high-antibacterial activity of urtica spp. seed extracts on food and plant pathogenic bacteria.the aim of this study was to comparatively evaluate antibacterial activities of methanol (metoh) and aqueous (dw) leaf (l), root (r) and seed (s) extracts of urtica dioica l. (ud; stinging nettle) and urtica pilulifera l. (up; roman nettle) on both food- and plant-borne pathogens, with total phenolic contents and dpph radical scavenging activities (drsa). metoh extracts of leaves and roots of u. dioica had the highest drsa. extracts with high antibacterial activity were in the order up-lmetoh (1 ...201323067263
carbohydrate binding properties of the stinging nettle (urtica dioica) rhizome lectin.the interaction of the stinging nettle rhizome lectin (uda) with carbohydrates was studied by using the techniques of quantitative precipitation, hapten inhibition, equilibrium dialysis, and uv difference spectroscopy. the carbohydrate binding site of uda was determined to be complementary to an n,n',n"-triacetylchitotriose unit and proposed to consist of three subsites, each of which has a slightly different binding specificity. uda also has a hydrophobic interacting region adjacent to the carb ...20133740853
plant food supplements with anti-inflammatory properties: a systematic review (ii).the aim of this systematic review is to summarize the evidence for or against the efficacy of plant food supplements (pfs) for coping inflammatory conditions by considering epidemiological and human intervention studies. the review considers six botanical species commonly used as food supplements/medicinals: urtica dioica l., symphytum officinalis l., calendula officinalis l., curcuma longa l., boswellia serrata roxb., and harpagophytum procumbens l. the search retrieved 579 publications. by rem ...201323391017
effect of cooking methods on antioxidant activity and nitrate content of selected wild mediterranean plants.wild edible plants (wep), traditionally consumed in the mediterranean diet, are considered a rich source of natural antioxidants but can also accumulate significant amount of nitrates. most wep are cooked before consumption, therefore, a study was conducted to evaluate the effects of boiling, steaming and microwave cooking processes on the total antioxidant activity (taa) and nitrate content of eight common wep. boiling caused the highest losses of taa, resulting in a reduction of the taa on dry ...201323701122
iranian medicinal plants for diabetes mellitus: a systematic review.in the iranian traditional medicine a significant usage of herbs is promoted for their anti-diabetic activity. the aim of this review to assess the efficacy of glucose lowering effects of medicinal plants cultivated in iran. an electronic literature search of medline, science direct, embase, scopus, web of science, cochrane library database, ebsco and google scholar from database inception conducted up to may 2012. a total of 85 studies (18 humans and 67 animals) examining 62 plants were reviewe ...201324498803
antihyperlipidemic effect of a polyherbal mixture in streptozotocin-induced diabetic rats.the effects of a polyherbal mixture containing allium sativum, cinnamomum zeylanicum, citrullus colocynthis, juglans regia, nigella sativa, olea europaea, punica granatum, salvia officinalis, teucrium polium, trigonella foenum, urtica dioica, and vaccinium arctostaphylos were tested on biochemical parameters in diabetic rats. the animals were randomized into three groups: (1) normal control, (2) diabetic control, and (3) diabetic rats which received diet containing 15% (w/w) of this mixture for ...201324383002
scientific basis of botanical medicine as alternative remedies for rheumatoid arthritis.rheumatoid arthritis (ra) is a chronic, systemic autoimmune inflammatory disorder that causes permanent disability and mortality to approximately 1 to 100 people in the world. patients with ra not only suffer from pain, stiffness, swelling, and loss of function in their joints, but also have a higher risk of cardiovascular disease and lymphoma. typically prescribed medications, including pain-relieving drugs, nonsteroidal anti-inflammatory drugs (nsaid), and disease-modifying antirheumatic drugs ...201322700248
screening of immunomodulatory activity of total and protein extracts of some moroccan medicinal plants.herbal and traditional medicines are being widely used in practice in many countries for their benefits of treating different ailments. a large number of plants in morocco were used in folk medicine to treat immune-related disorders. the objective of this study is to evaluate the immunomodulatory activity of protein extracts (pes) of 14 moroccan medicinal plants. this activity was tested on the proliferation of immune cells. the prepared total and pes of the plant samples were tested using mtt ( ...201322301818
[study of antioxidant activity of phenolic compounds from some species of georgian flora].the antioxidant activity of extracts obtained from different parts of georgian flora species hamamelis virginiana l., astragalus caucasicus pall., astragalus microcephalus willd., vitis vinifera l., rhododendron ponticum l., rhododendron ungernii trautv., ginkgo biloba l., salvia officinalis l., querqus iberica stev., maclura aurantiaca nutt., cotinus coggygria ledeb., fraxinus ornus l., urtica dioica l., rhododendron caucasicum pall., pueraria hirsuta matsum., geranium pusillum l., astragalus t ...201324099817
a lectin microarray study of glycoantigens in neonatal porcine islet-like cell clusters.besides α-gal expression, the differences of glycosylation and antigenicity between adult pig islets (apis) and neonatal porcine islet-like cell clusters (npccs) are altogether unclear. in this study, lectin microarray analyses of npccs were performed and the results compared with the corresponding values for wild-type apis and npccs from α-gal transferase knockout (galt-ko) pig.201323769020
identification and phenology of hyalesthes obsoletus (hemiptera: auchenorrhyncha: cixiidae) nymphal instars.urtica dioica and convolvulus arvensis are the main host plants of hyalesthes obsoletus and play an important role in the epidemiology of bois noir of grapevines. the earliest survey, which was carried out to compare the phenology of nymphal instars on u. dioica and c. arvensis, had highlighted some problems in the identification of the instars. therefore, the correct identification of nymphs to species and instar level became a preliminary aim of this research. adults and nymphs attributable to ...201222360966
nonvolatile chemical cues affect host-plant ranking by gravid polygonia c-album females.in a multiple-choice test, the preference of egg-laying polygonia c-album (comma butterfly) females was studied for oviposition on plants bearing surrogate leaves treated with crude methanol extracts obtained from leaves of seven host-plant species: humulus lupulus, urtica dioica, ulmus glabra, salix caprea, ribes nigrum, corylus avellana, and betula pubescens. the ranking order of surrogate leaves treated with host-plant extracts corresponded well to that reported on natural foliage, except r. ...201222486046
screening antimicrobial activity of various extracts of urtica dioica.urtica dioica or stinging nettle is traditionally used as an herbal medicine in western asia. the current study represents the investigation of antimicrobial activity of u. dioica from nine crude extracts that were prepared using different organic solvents, obtained from two extraction methods: the soxhlet extractor (method i), which included the use of four solvents with ethyl acetate and hexane, or the sequential partitions (method ii) with a five solvent system (butanol). the antibacterial an ...201223342511
impact of vector dispersal and host-plant fidelity on the dissemination of an emerging plant pathogen.dissemination of vector-transmitted pathogens depend on the survival and dispersal of the vector and the vector's ability to transmit the pathogen, while the host range of vector and pathogen determine the breath of transmission possibilities. in this study, we address how the interaction between dispersal and plant fidelities of a pathogen (stolbur phytoplasma tuf-a) and its vector (hyalesthes obsoletus: cixiidae) affect the emergence of the pathogen. using genetic markers, we analysed the geog ...201223284774
medicinal plants extracts affect virulence factors expression and biofilm formation by the uropathogenic escherichia coli.medicinal plants are an important source for the therapeutic remedies of various diseases including urinary tract infections. this prompted us to perform research in this area. we decided to focus on medicinal plants species used in urinary tract infections prevention. the aim of our study was to determine the influence of betula pendula, equisetum arvense, herniaria glabra, galium odoratum, urtica dioica, and vaccinium vitis-idaea extracts on bacterial survival and virulence factors involved in ...201222915095
an evaluation of the inhibitory effects against rotavirus infection of edible plant extracts.rotaviruses are the single most important cause of severe diarrhea in young children worldwide. the developments of specific, potent and accessible antiviral treatments that restrain rotavirus infection remain important to control rotavirus disease.201222834653
upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper.acute gastrointestinal (gi) bleeding is one of the most frequent causes for hospitalization and responsible for a major cause of morbidity and mortality among patients. ankaferd blood stopper (abs) is a herbal extract attained from five different plants thymus vulgaris, glycyrrhiza glabra, vitis vinifera, alpinia officinarum and urtica dioica. here we report a challenging upper gi bleeding case with a low platelet count and defective hemostasis treated endoscopically with abs as an adjunctive dr ...201120677211
inhibition of severe acute respiratory syndrome coronavirus replication in a lethal sars-cov balb/c mouse model by stinging nettle lectin, urtica dioica agglutinin.urtica dioica agglutinin (uda) is a small plant monomeric lectin, 8.7 kda in size, with an n-acetylglucosamine specificity that inhibits viruses from nidovirales in vitro. in the current study, we first examined the efficacy of uda on the replication of different sars-cov strains in vero 76 cells. uda inhibited virus replication in a dose-dependent manner and reduced virus yields of the urbani strain by 90% at 1.1 ± 0.4 µg/ml in vero 76 cells. then, uda was tested for efficacy in a lethal sars-c ...201121338626
a new method for in situ measurement of bt-maize pollen deposition on host-plant leaves.maize is wind pollinated and produces huge amounts of pollen. in consequence, the cry toxins expressed in the pollen of bt maize will be dispersed by wind in the surrounding vegetation leading to exposure of non-target organisms (nto). nto like lepidopteran larvae may be affected by the uptake of bt-pollen deposited on their host plants. although some information is available to estimate pollen deposition on host plants, recorded data are based on indirect measurements such as shaking or washing ...201126467496
phenolic composition and antioxidant properties of some traditionally used medicinal plants affected by the extraction time and hydrolysis.polyphenolic phytochemicals in traditionally used medicinal plants act as powerful antioxidants, which aroused an increasing interest in their application in functional food development.201120848396
plants growing on contaminated and brownfield sites appropriate for use in organisation for economic co-operation and development terrestrial plant growth test.the organisation for economic co-operation and development (oecd) terrestrial plant test is often used for the ecological risk assessment of contaminated land. however, its origins in plant protection product testing mean that the species recommended in the oecd guidelines are unlikely to occur on contaminated land. six alternative species were tested on contaminated soils from a former zn smelter and a metal fragmentizer with elevated concentrations of cd, cu, pb, and zn. the response of the al ...201120853450
pharmaceutical ethnobotany in the riverside of navarra (iberian peninsula).this paper provides significant ethnobotanical information on pharmaceutical plant uses in the riverside of navarra. thereby, it will extend and complement a recent previous study carried out in the northern navarra. this paper aim to collect, analyse and evaluate the ethnobotanical knowledge about medicinal plants in the riverside of navarra (iberian peninsula) with 2554.4km(2) and 144,674 inhabitants.201121345364
mechanism of action of stinging nettles.inadvertent exposure to the ubiquitous weed, urtica dioica, called "stinging nettles" produces an immediate stinging and burning sensation on the skin. this investigation evaluates the structural effect that stinging nettle spicules may have on the clinical manifestation of these symptoms. this hypothesis was investigated by exposing murine skin to stinging nettles and then evaluating the skin using electron microscopy. it was hypothesized that the mechanism of action of stinging nettles is both ...201121396858
suppression of growth and invasive behavior of human prostate cancer cells by prostacaid™: mechanism of activity.since the use of dietary supplements as alternative treatments or adjuvant therapies in cancer treatment is growing, a scientific verification of their biological activity and the detailed mechanisms of their action are necessary for the acceptance of dietary supplements in conventional cancer treatments. in the present study we have evaluated the anti-cancer effects of dietary supplement prostacaid™ (pc) which contains mycelium from medicinal mushrooms (ganoderma lucidum, coriolus versicolor, p ...201121468543
was the famous astronomer copernicus also a nephrologist.nicolaus copernicus (1473-1543), world-famous astronomer, born in toruń, was also a warmian canon (senior priest) and a physician to 4 consecutive prince-bishops of warmia and of other warmian canons. what medical conditions preoccupied nicolaus copernicus and whether they included kidney diseases can only be inferred from the extant prescriptions of copernicus, as no record remains of any treatises by copernicus regarding medicine. while no prescription penned by him is dated, several are trace ...201121614777
ameliorative effects of stinging nettle (urtica dioica) on testosterone-induced prostatic hyperplasia in rats.the present study investigated the effects of stinging nettle (urtica dioica l.) (ud) on benign prostatic hyperplasia (bph) induced by testosterone. in vitro studies were conducted to assess the 5a-reductase inhibitory potential of ud. two biochemical markers viz., ß-sitosterol and scopoletin, were isolated and characterised in the extracts utilising high-performance thin layer chromatographic, ftir, nmr and overlain uv spectral studies. hyperplasia was induced in rats by subcutaneous administra ...201121806658
organic parasite control for poultry and rabbits in british columbia, canada.abstract: plants used for treating endo- and ectoparasites of rabbits and poultry in british columbia included arctium lappa (burdock), artemisia sp. (wormwood), chenopodium album (lambsquarters) and c. ambrosioides (epazote), cirsium arvense (canada thistle), juniperus spp. (juniper), mentha piperita (peppermint), nicotiana sp. (tobacco), papaver somniferum (opium poppy), rubus spp. (blackberry and raspberry relatives), symphytum officinale (comfrey), taraxacum officinale (common dandelion), th ...201121756341
ethnopharmacological survey of medicinal plants in maden (elazig-turkey).this study aimed to identify wild plants collected for medical purposes by the local people of maden county, located in the eastern anatolia region of turkey, and to establish the uses and local names of these plants.201121704144
broad antiviral activity of carbohydrate-binding agents against the four serotypes of dengue virus in monocyte-derived dendritic cells.dendritic cells (dc), present in the skin, are the first target cells of dengue virus (denv). dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (dc-sign) is present on dc and recognizes n-glycosylation sites on the e-glycoprotein of denv. thus, the dc-sign/e-glycoprotein interaction can be considered as an important target for inhibitors of viral replication. we evaluated various carbohydrate-binding agents (cbas) against all four described serotypes of denv replica ...201121738755
in vitro antimicrobial activity of romanian medicinal plants hydroalcoholic extracts on planktonic and adhered cells.the aim of this study was to assess the antibacterial and antifungal potential of some romanian medicinal plants, arnica--arnica montana, wormwood--artemisia absinthium and nettle--urtica dioica. in order to perform this antimicrobial screening, we obtained the vegetal extracts and we tested them on a series of gram-positive and gram-negative bacteria, and also against two fungal strains. the vegetal extracts showed antimicrobial activity preferentially directed against the planktonic fungal and ...201121717806
The Effect of Stinging Nettle (Urtica dioica) Seed Oil on Experimental Colitis in Rats.Abstract This study investigated the effect of Urtica dioica, known as stinging nettle, seed oil (UDO) treatment on colonic tissue and blood parameters of trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats. Experimental colitis was induced with 1?mL of TNBS in 40% ethanol by intracolonic administration with a 8-cm-long cannula with rats under ether anesthesia, assigned to a colitis group and a colitis+UDO group. Rats in the control group were given saline at the same volume by intrac ...201121861725
ankaferd hemostat in the management of gastrointestinal hemorrhages.gastrointestinal (gi) bleeding refers to any hemorrhage ascribed to the pathologies of the gastrointestinal tract, extending from the mouth to the anal canal. despite the recent improvements in the endoscopic, hemostatic and adjuvant pharmacologic techniques, the reported mortality is still around 5%-10% for peptic ulcer bleeding and about 15%-20% for variceal hemorrhages. although endoscopic management reduces the rates of re-bleeding, surgery, and mortality in active bleeding; early recurrence ...201122046083
ameliorative influence of urtica dioica l against cisplatin-induced toxicity in mice bearing ehrlich ascites carcinoma.abstract cisplatin (cp) is a widely used cytotoxic agent against cancer, and high doses of cp have been known to cause nephrotoxicity and hepatotoxicity. some reports claim that antioxidants can reduce cp-induced toxicity. this study investigated the hepatoprotective, nephroprotective, and antioxidant activity of urtica dioica l methanolic extract (udme) against cp toxicity in erhlich ascites tumor (eat)-bearing mice. levels of serum hepatic enzymes, renal function markers, and oxidant/antioxida ...201121939360
effects of drugs of plant origin on the development of the immune response.the effects of extracts from licorice (glycyrrhisa glabra), great nettle (urtica dioica), common burdock (arctium lappa), and bur marigold (bidens tripartite) on the humoral and cellular immune response and nonspecific resistance in mice were studied. burdock and bur marigold extracts stimulated the humoral immune response, nettle and licorice extracts stimulated cellular response and nonspecific resistance, their effects being superior to those of pharmacopoeial echinacea purpurea tincture.201122238748
survey of microfungi in the landschaftspark duisburg-nord (germany).during an excursion in the landschaftspark duisburg-nord in 2009 and 2010 we were able to collect and identify more than 100 specimens of microfungi on different parts of cultivated and wild plant species. we found parasitic and saprophytic microfungi on trees, bushes and herbaceous plants. some of them have been observed only rarely until now. most of the collected microfungi species belong to the classes of ascomycetes, basidiomycetes and deuteromycetes - for example leptosphaeria modesta (des ...201122702187
content of toxic and essential metals in medicinal herbs growing in polluted and unpolluted areas of macedonia.the aim of this study was to determine and compare ba, cr, cd, fe, sr, pb, and zn content in medicinal herbs urtica dioica l., taraxacum officinale, and matricaria recutita growing in polluted and unpolluted areas of the republic of macedonia. the metal content was determined using inductively coupled plasma atomic emission spectroscopy (icp-aes). in the unpolluted area of mt. plackovica the metal content in taraxacum officinale was in the descending order: fe>sr>zn>ba>cr, while pb and cd were b ...201020860970
[associating serenoa repens, urtica dioica and pinus pinaster. safety and efficacy in the treatment of lower urinary tract symptoms. prospective study on 320 patients].serenoa repens (saw palmetto) has been employed for the treatment of lower urinary tract symptoms (luts) for several years. its mechanism of action is believed to be due to antiandrogenic, antiproliferative and antinflammatory properties. an association of serenoa with the nettle "urtica dioica" showing antiproliferative activity and the pine "pinus pinaster" derivative, showing antinflammatory action, has been proposed in recent years. such an action is hoped to act not only by reducing luts bu ...201020890858
protective role of urtica dioica l. (urticaceae) extract on hepatocytes morphometric changes in stz diabetic wistar rats.the present investigation was carried out to evaluate the protective effect of the hydroalcoholic extract of urtica dioica leaves on the quantitative morphometric changes in the liver of streptozotocin-induced diabetic rats.201020931430
effect of bt-176 maize pollen on first instar larvae of the peacock butterfly (inachis io) (lepidoptera; nymphalidae).more than 10 years after registration of the first bt maize cultivar in europe, there still exists a remarkable lack of data on effects on lepidoptera which would be necessary for a complete and comprehensive environmental risk assessment. so far only very few european butterfly species have been tested in this aspect. in our study the effect of transgenic bacillus thuringiensis (bt) maize pollen (event bt-176) on the development and survival of neonate larvae of the peacock butterfly, inachis i ...201021122482
evaluation of hemostatic effects of ankaferd as an alternative medicine.ankaferd blood stopper (abs), a unique traditional herbal mixture, has been used topically to stop bleeding for centuries in anatolia. abs is a standardized mixture of the plants thymus vulgaris, glycyrrhiza glabra, vitis vinifera, alpinia officinarum, and urtica dioica. through its effects on the endothelium, blood cells, angiogenesis, cellular proliferation, vascular dynamics, and cell mediators, abs is now becoming an official alternative hemostatic medicine for intractable bleedings that are ...201021194248
the determination and fidelity level of medicinal plants used to make traditional turkish salves.this study has been done in order to identify plants that were used to make traditional turkish salves between 2007 and 2008.201020192916
a thermostable lectin from the rhizomes of kaempferia parviflora.kaempferia parviflora, or black galingale (kra-chai-dam), belongs to the zingiberaceae family and is used as both a food ingredient and a medicinal plant. there are diverse reports on the biological activities of compounds extracted from the plant, such as antimalarial, antifungal and an effective sexual-enhancing role, but not on the lectins.201020549650
effects of water extract of urtica dioica l. and modified atmosphere packaging on the shelf life of ground beef.effects of lyophilized urtica dioica l. water extract (luwe) and modified atmosphere packaging (map) on the quality and shelf life of ground beef were investigated. ground beef was stored as aerobic control, map (80%o(2)+20% co(2)), map+250 ppm luwe and map and 500 ppm luwe at 2+/-0.5 degrees c for 14 days. map and luwe had significant effects on mesophilic, psychrotrophic and lactic acid bacteria and pseudomonas counts. depending on the level of luwe, pseudomonas and psychrotrophic counts decre ...201020573457
a rat model of urtica ferox neuropathy.a species of stinging nettle, urtica ferox, is indigenous to new zealand and has caused deaths in animals and humans. we previously reported a human case of acute polyneuropathy due to u. ferox stings. we developed an experimental animal model of u. ferox toxin neuropathy to determine its neurophysiological and pathological characteristics. male wistar rats received either normal saline or fluid from u. ferox trichomes by injection into the epineurium of the left sciatic nerve. neurophysiologica ...201020650289
antimicrobial effect of garlic (allium sativum).medicinal plants like pumpkin seed, thyme, onion, nigella sativa, lemon balm, and stinging nettle are used extensively today. one of these plants used most intensively and widespread is garlic. in this context, fresh shape, powder state and oil of garlic have been used all around the world, especially in far east for centuries. it is scientifically proven that garlic is effectively used in cardiovascular diseases as a regulator of blood pressure, with dropper effects on glycaemia and high blood ...201019929845
insulin mimetics in urtica dioica: structural and computational analyses of urtica dioica extracts.urtica dioica (ud) is a plant shown to reduce blood glucose levels upon oral ingestion; however, neither its active component nor its mechanism of action has been identified. one active fraction of this extract, termed ud-1, was separated by molecular sieve column chromatography and purified by high performance liquid chromatography (hplc). while ud-1 did not stimulate insulin secretion in glucose-responsive min6 clonal beta-cells, chronic exposure (24 h) significantly enhanced glucose uptake (a ...201020013820
use of lupin, lupinus perennis, mango, mangifera indica, and stinging nettle, urtica dioica, as feed additives to prevent aeromonas hydrophila infection in rainbow trout, oncorhynchus mykiss (walbaum).feeding rainbow trout, oncorhynchus mykiss (walbaum), with 1% lupin, lupinus perennis, mango, mangifera indica, or stinging nettle, urtica dioica, for 14 days led to reductions in mortality after challenge with aeromonas hydrophila. in addition, there was significant enhancement in serum bactericidal activity, respiratory burst and lysozyme activity in the treatment groups compared to the controls. use of lupin and mango led to the highest number of red blood and white blood cells in recipient f ...201020102439
antidiabetic effect of some medicinal plants of oriental morocco in neonatal non-insulin-dependent diabetes mellitus rats.the goal of the present study is to test the effect of water extract (we) of four medicinal plants used as antidiabetics in eastern morocco (arbutus unedo: au, ammoïdes pusilla: ap, thymelaea hirsuta: th, and urtica dioïca: ud). these plants are used in cooking to bring out the flavor in a dish or to complement it. the first experiment was realized in order to determine the antidiabetic effect of the we of these plants during 5 weeks' treatment. seven groups of wistar rats were used: healthy con ...201020154101
effects of urtica dioica on hepatic ischemia-reperfusion injury in rats.to evaluate the effects of urtica dioica on hepatic ischemia-reperfusion injury.201021340227
an ethnobotanical survey of medicinal plants in sivrice (elazığ-turkey).this study aimed to identify wild plants collected for medical purposes by the local people of sivrice county, located in the eastern anatolia region of turkey, and to establish the uses and local names of these plants.201020713142
regulation of inflammatory gene expression in pbmcs by immunostimulatory botanicals.many hundreds of botanicals are used in complementary and alternative medicine for therapeutic use as antimicrobials and immune stimulators. while there exists many centuries of anecdotal evidence and few clinical studies on the activity and efficacy of these botanicals, limited scientific evidence exists on the ability of these botanicals to modulate the immune and inflammatory responses. using botanogenomics (or herbogenomics), this study provides novel insight into inflammatory genes which ar ...201020838436
[experience in treating digestive organ diseases with medicinal plants].results are reported of treatment of chronic hyposecretory gastritis, chronic hepatocholecystitis and angiocholitis by a herbal complex. the herbal composition included achillea millefolium, urtica dioica, cichorium (aboveground part), polygonum, matricaria chamomilla (flowers), helichrysum arenarium, calendula (flowers), corn stigmas, humulus lupulus (racemes) in proportion 3:3:1:1:2:1:1:2:1 respectively. the herbal decoction is to be taken 3 times daily before meals. diet n 5 (pevzner scheme) ...20092750130
complementary and alternative medicine in cancer patients - analysis of influencing factors in turkey.this cross-sectional and descriptive study analysed complementary and alternative medicine (cam) practices of patients with cancer diagnoses and influencing factors.200920192589
in vivo hemostatic effect of the medicinal plant extract ankaferd blood stopper in rats pretreated with warfarin.ankaferd comprises a mixture of thymus vulgaris, glycyrrhiza glabra, vitis vinifera, alpinia officinarum and urtica dioica. ankaferd blood stopper (abs) has been approved in the management of bleedings. this study aimed to evaluate in vivo hemostatic effect of abs in rats pretreated with warfarin.200919117967
effects of urtica dioica extract on lipid profile in hypercholesterolemic rats.to investigate the effects of extract of urtica dioica, a perennial herb in iran, on lipid profile in hypercholesterolemic rats.200919435556
the effect of urtica dioica extract on the number of astrocytes in the dentate gyrus of diabetic rats.diabetes mellitus is associated with cerebral alterations in both human and animal models of the disease. these alterations include abnormal expression of hypothalamic neuropeptides and hippocampal astrogliosis. urtica dioica (nettle) is among several species listed for their use against diabetes in folk medicine. the aim of this study was the evaluation of the astrocyte number in the dentate gyrus of diabetic rats after treatment with nettle. a total of 21 male albino wistar rats were used in t ...200919449296
characterization of bois noir isolates by restriction fragment length polymorphism of a stolbur-specific putative membrane protein gene.bois noir phytoplasma (bnp), widespread in wine-producing areas of europe and endemic in france and italy, is classified in the 16srxii-a subgroup, whose members are referred to as stolbur phytoplasmas. the 16s rdna gene of stolbur phytoplasma shows low variability, and few non-ribosomal genes are available as markers to assess variation among isolates. we used the stolbur-specific stol-1h10 gene, encoding a putative membrane-exposed protein, to investigate genetic diversity of french and italia ...200919453230
antifungal activity of nettle (urtica dioica l.), colocynth (citrullus colocynthis l. schrad), oleander (nerium oleander l.) and konar (ziziphus spina-christi l.) extracts on plants pathogenic fungi.anti-mycotic activity of the ethanol extracts from nettle (urtica dioica l.), colocynth (citrullus colocynthis l. schrad), konar (ziziphus spina-christi l.) and oleander (nerium oleander l.) floral parts were screened in vitro against four important plant pathogenic fungi viz.; alternaria alternate, fusarium oxysporum, fusarium solani and rizoctonia solani using agar dilution bioassay. extracts showed antifungal activity against all the tested fungi. among the plants, nettle and colocynth were t ...200919579919
the effects of urtica dioica l. leaf extract on aniline 4-hydroxylase in mice.the effects of hydroalcoholic (80% ethanol-20% water) extract of urtica dioica l. on microsomal aniline 4-hydroxylase (a4h) were investigated in the liver of swiss albino mice (8- 10-weeks-old) treated with two doses (50 and 100 mg/kg body weight, given orally for 14 days ). the activities of a4h showed a significant increase in the liver at both dose levels of extract treatment. the hydroalcoholic extract of urtica dioica induced the activities of a4h that had been increased by treatment of met ...200919645331
complementary-alternative medicine among cancer patients in the western region of turkey.to investigate the complementary/alternative medicine (cam) applications and factors affecting its use among cancer patients in the western region of turkey.200919650177
the efficacy of ankaferd blood stopper in antithrombotic drug-induced primary and secondary hemostatic abnormalities of a rat-bleeding model.ankaferd comprises a standardized mixture of plants thymus vulgaris, glycyrrhiza glabra, vitis vinifera, alpinia officinarum and urtica dioica. ankaferd blood stopper (abs) as a medicinal product has been approved in the management of external hemorrhage and dental surgery bleedings in turkey. this study aimed to evaluate the in-vivo hemostatic effect of abs in rats pretreated with acetylsalicylic acid or enoxaparin. wistar rats (210-270 g) of both sexes were used in this study. the animals were ...200919657315
a new mouse-adapted strain of sars-cov as a lethal model for evaluating antiviral agents in vitro and in vivo.severe acute respiratory syndrome (sars) is a highly lethal emerging disease caused by coronavirus sars-cov. new lethal animal models for sars were needed to facilitate antiviral research. we adapted and characterized a new strain of sars-cov (strain v2163) that was highly lethal in 5- to 6-week-old balb/c mice. it had nine mutations affecting 10 amino acid residues. strain v2163 increased il-1alpha, il-6, mip-1alpha, mcp-1, and rantes in mice, and high il-6 expression correlated with mortality. ...200919853271
an investigation on the anticandidal activity of some traditional medicinal plants in turkey.methanol and chloroform extracts obtained from eight plant species belonging to six families, which were selected depending on their use in turkish folk medicine, including mentha longifolia l. (labiatae), mentha piperita l. hudson (labiatae), prongos ferulaceae (umbelliferae), galium verum l. (rubiaceae), salvia limbata c. a meyer (labiatae), artemisia austriaca jacq. (artemiceae), plantago lanceolata l. (plantaginaceae) and urtica dioica l. (urticaceae) were evaluated for their in vitro antica ...200918522697
the beneficial effects of nettle supplementation and exercise on brain lesion and memory in rat.regular swimming and phytotherapeutic supplementation are assumed to alleviate the severity of neurodegeneration leading to dementia. the effect of swimming training and that of enriched lab chow containing 1% (w/w) dried nettle (urtica dioica) leaf on the prevention of severity of brain injury caused by n-methyl-d-aspartate (nmda) lesion in wistar rats were investigated. nettle supplementation and regular swimming exercise seem to improve the adverse effect of brain injury caused by nmda lesion ...200919071007
effects of urtica dioica l. seed on lipid peroxidation, antioxidants and liver pathology in aflatoxin-induced tissue injury in rats.this study was carried out to investigate the hepatoprotective and antioxidant properties of urtica dioica l. seeds (uds) extract against aflatoxin (af)-exposure in rats. the preventive potential and antioxidant capacity of the plant's extract was evaluated by liver histopathological changes, measuring serum marker enzymes, antioxidant defense systems and lipid peroxidation (malondialdehyde, mda) content in some tissues of rats. eighteen rats were randomly divided into one of three experimental ...200919073231
complementary alternative medicine use in children with type 1 diabetes mellitus in erzurum, turkey.the aims of this study were: (i) to determine the types of complementary and alternative medicine use among children with type i diabetes mellitus as reported by parents and (ii) to describe sociodemographic and medical factors associated with the use of such treatments in families residing in eastern turkey.200919077023
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