Publications
Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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screening probiotic candidates for a mixture of probiotics to enhance the growth performance, immunity, and disease resistance of asian seabass, lates calcarifer (bloch), against aeromonas hydrophila. | six bacteria, including, lactobacillus casei m15, lac. plantarum d8, lac. pentosus bd6, lac. fermentum lw2, enterococcus faecium 10-10, and bacillus subtilis e20, and one yeast, saccharomyces cerevisiae p13 were selected as probiotics for asian seabass, lates calcarifer, by tracking the growth performance and disease resistance of fish against aeromonas hydrophila in the first trial. the probiotic efficiency screening results showed that b. subtilis e20 and lac. pentosus bd6, and s. cerevisiae p ... | 2017 | 27838565 |
potential synergistic effects of a mixture of mineral trioxide aggregate (mta) cement and bacillus subtilis in dental caries treatment. | bacillus subtilis is nonpathogenic in humans and produces a number of useful substances and, therefore, this bacterium is used in probiotic therapy. there have been trials of b. subtilis for patients with periodontitis, but not for patients with caries. similarly, mineral trioxide aggregate (mta) cement has been widely used for endodontic treatment, but there are few reports of its use for caries. therefore, examinations were performed regarding the benefits of addition of b. subtilis to mta cem ... | 2017 | 28342006 |
possible correlation between levansucrase production and probiotic activity of bacillus sp. isolated from honey and honey bee. | five bacterial isolates from honey and bee gut were selected based on their high levansucrase activity and levan yield which were strongly positively correlated. all isolates showed good tolerance to temperature up to 70 °c, to nacl up to 3 m and to 0.1% h2o2. they maintained over 59 and 64% survival at ph 9.0 and 2.0 respectively, but showed varying tolerance to 0.1% bile salts and pancreatic enzymes. most isolates were susceptible to widely used antibiotics, but demonstrated diverse antimicrob ... | 2017 | 28271385 |
oral immunization against candidiasis using lactobacillus casei displaying enolase 1 from candida albicans. | candidiasis is a common fungal infection that is prevalent in immunocompromised individuals. in this study, an oral vaccine against candida albicans was developed by using the molecular display approach. enolase 1 protein (eno1p) of c. albicans was expressed on the lactobacillus casei cell surface by using poly-gamma-glutamic acid synthetase complex a from bacillus subtilis as an anchoring protein. the eno1p-displaying l. casei cells were used to immunize mice, which were later challenged with a ... | 2017 | 25853077 |
the effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. | this study was designed to evaluate the effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes among subjects with gestational diabetes (gdm). | 2017 | 28326881 |
probiotic supplementation in diabetic hemodialysis patients has beneficial metabolic effects. | this study determined the effects of probiotic supplementation on glycemic control, lipid concentrations, biomarkers of inflammation and oxidative stress in 60 diabetic patients on hemodialysis in a parallel randomized double-blind placebo-controlled clinical trial. participants were initially matched based on sex, duration of dialysis and diabetes, body mass index and age. subsequently, they were randomly divided into two groups to take either a capsule containing the probiotics lactobacillus a ... | 2017 | 27927601 |
a randomized controlled clinical trial investigating the effect of synbiotic administration on markers of insulin metabolism and lipid profiles in overweight type 2 diabetic patients with coronary heart disease. | objective: the current study was performed to evaluate the effects of synbiotic administration on metabolic profiles in overweight diabetic patients with coronary heart disease (chd). methods: this randomized, double-blind, placebo-controlled trial was done among 60 diabetic patients with chd. participants were randomly divided into 2 groups: group a (n=30) received synbiotic supplements containing 3 probiotic bacteria spices lactobacillus acidophilus 2×10(9), lactobacillus casei 2×10(9), bifido ... | 2017 | 27219886 |
the role of probiotics in the treatment of dysentery: a randomized double-blind clinical trial. | diarrhea is considered as an important cause of morbidity and mortality, even though one of the main reasons of death following diarrhea is initiated by dysentery. in recent years, the consumption of probiotics has been proposed for the treatment of infectious diarrhea. despite most of the studies on probiotics have focused on acute watery diarrhea, few studies in the field of dysentery have found beneficial effects of probiotics. this study is a randomized double-blind clinical trial. the patie ... | 2017 | 28321826 |
energy dispersive x-ray microanalysis, fluoride release, and antimicrobial properties of glass ionomer cements indicated for atraumatic restorative treatment. | the aim of this study was to compare constituents of glass powder, fluoride release, and antimicrobial properties of new atraumatic restorative treatment material with zirconia fillers and conventional glass ionomer cement (gic) type ix. | 2017 | 27583226 |
inhibitory effects of lactobacillus rhamnosus and lactobacillus casei on candida biofilm of denture surface. | candida albicans biofilm is associated with denture-related stomatitis and oral candidiasis of elderly. probiotics are beneficial bacteria and have antibacterial activity against pathogenic bacteria. the purpose of this study was to investigate the antifungal activity of various probiotics against c. albicans and the inhibitory effects of probiotics on candida biofilm on the denture surface. | 2017 | 28063305 |
effects of lactobacillus casei and enterococcus faecalis on growth performance, immune function and gut microbiota of suckling piglets. | this study was carried out to investigate the effects of orally administrated lactobacillus casei and enterococcus faecalis on performance, immune function and gut microbiota of suckling piglets. neonatal piglets (n = 120) were randomly assigned to 4 groups, with 30 suckling piglets in each group. the piglets were from 15 litters, one male and one female piglet were selected for each group in each litter. the control group was administrated with normal saline, the other groups with l. casei or e ... | 2017 | 28201936 |
intestinal iga as a modulator of the gut microbiota. | accumulating evidence suggests that dysbiosis plays a role in the pathogenesis of intestinal diseases including inflammatory bowel disease (ibd) as well as extra-intestinal disorders. as a modulator of the intestinal microbiota, we isolated a mouse monoclonal iga antibody (clone w27) with high affinities for multiple commensal bacteria, but not for beneficial bacteria such as lactobacillus casei (l. casei). via specific recognition of an epitope in serine hydroxymethyltransferase (shmt), a bacte ... | 2017 | 28384049 |
inducer exclusion in firmicutes: insights into the regulation of a carbohydrate atp binding cassette transporter from lactobacillus casei bl23 by the signal transducing protein p-ser46-hpr. | catabolite repression is a mechanism that enables bacteria to control carbon utilization. as part of this global regulatory network, components of the phosphoenolpyruvate:carbohydrate phosphotransferase system inhibit the uptake of less favourable sugars when a preferred carbon source such as glucose is available. this process is termed inducer exclusion. in bacteria belonging to the phylum firmicutes, hpr, phosphorylated at serine 46 (p-ser46-hpr) is the key player but its mode of action is elu ... | 2017 | 28370477 |
changes of sodium nitrate, nitrite, and n-nitrosodiethylamine during in vitro human digestion. | this study aimed to determine the changes in sodium nitrate, sodium nitrite, and n-nitrosodiethylamine (ndea) during in vitro human digestion, and the effect of enterobacteria on the changes in these compounds. the concentrations of nitrate, nitrite, and ndea were significantly reduced from 150, 150, and 1ppm to 42.8, 63.2, and 0.85ppm, respectively, during in vitro human digestion (p<0.05). the enterobacteria escherichia coli and lactobacillus casei reduced the amount of these compounds present ... | 2017 | 28193415 |
immunogenicity of recombinant lactobacillus casei-expressing f4 (k88) fimbrial adhesin faeg in conjunction with a heat-labile enterotoxin a (ltak63) and heat-labile enterotoxin b (ltb) of enterotoxigenic escherichia coli as an oral adjuvant in mice. | the aims of this study were to develop an effective oral vaccine against enterotoxigenic escherichia coli (etec) infection and to design new and more versatile mucosal adjuvants. | 2017 | 27860074 |
influence of pdo ragusano cheese biofilm microbiota on flavour compounds formation. | the objectives of the present study were to characterize the biofilm microbiota of 11 different farms (from a to k), producing pdo ragusano cheese, and to investigate on its ability to generate volatile organic compounds (vocs) in milk samples inoculated with biofilm and incubated under ragusano cheese making conditions. the biofilms were subjected to plate counting and pcr/t/dgge analysis and the vocs generated in incubated milk samples were evaluated through smartnose, gc/o, and gc/ms. strepto ... | 2017 | 27697162 |
effect of lactobacillus casei on the pharmacokinetics of amiodarone in male wistar rats. | the probiotic bacterium escherichia coli strain nissle 1917 has previously been shown to alter the pharmacokinetics of amiodarone. the aim of this study was to determine whether the probiotic bacterium lactobacillus casei produces similar alterations in amiodarone disposition. | 2017 | 26797809 |
effect of flavonoid-rich extract of glycyrrhiza glabra on gut-friendly microorganisms, commercial probiotic preparations, and digestive enzymes. | flavonoid-rich extract prepared from glycyrrhiza glabra has been found to be beneficial in patients with functional dyspepsia and was reported to possess some gut health-promoting properties such as antioxidant, anti-inflammatory and anti-helicobacter pylori activities. in the present study, the flavonoid-rich extract of glycyrrhiza glabra was evaluated for its compatibility with probiotic strains (lactobacillus casei, lactobacillus fermentum, lactobacillus plantarum, and streptococcus thermophi ... | 2017 | 27588327 |
in vitro antagonistic activity of lactobacillus casei against helicobacter pylori. | helicobacter pylori is one of the most common causes of chronic infections in humans. curing h. pylori infection is difficult because of the habitat of the organism below the mucus adherent layer of gastric mucosa. lactobacilli are known as acid-resistant bacteria and can remain in stomach for a long time than any other organism, we aimed in this study to examine the efficacy of lactobacillus casei as a probiotic against h. pylori in humans. particularly, l. casei was opted as it is considered t ... | 2017 | 26691482 |
probiotic bacteria inhibit the bovine respiratory pathogen mannheimia haemolytica serotype 1 in vitro. | this study evaluated the potential of probiotic bacteria to inhibit growth and cell adhesion of the bovine respiratory pathogen mannheimia haemoltyica serotype 1. the inhibitory effects of nine probiotic strains (lactobacillus acidophilus, lactobacillus casei, lactobacillus helveticus, lactobacillus plantarum, lactobacillus rhamnosus, lactococcus lactis, streptococcus thermophilus and two paenibacillus polymyxa strains) against m. haemolytica were evaluated using a spot-on-lawn method. probiotic ... | 2017 | 28178767 |
potential prebiotic properties of cashew apple (anacardium occidentale l.) agro-industrial byproduct on lactobacillus species. | the prebiotic effects of a cashew apple (anacardium occidentale l.) agro-industrial byproduct powder (cap) on different potentially probiotic lactobacillus strains, namely lactobacillus acidophilus la-05, lactobacillus casei l-26 and lactobacillus paracasei l-10, were assessed using in vitro experimental models. accordingly, the growth of the lactobacillus strains when cultivated in a broth containing cap (20 or 30 g l(-1) ), glucose (20 g l(-1) ) or fructooligosaccharides (fos) (20 g l(-1) ) wa ... | 2017 | 28111773 |
anticariogenic activity and phytochemical studies of crude extract from some indian plant leaves. | the aim was to screen the selected indian plants for their antibacterial efficacy against four cariogenic bacteria lactobacillus acidophilus (la)(microbial type culture collection [mtcc]-*447), lactobacillus casei (lc) (mtcc-1423), streptococcus mutans (smu) (mtcc-890) and staphylococcus aureus (mtcc-96). to identify and characterize active principle present in these plants for the treatment of dental caries. | 2017 | 26401353 |
expression of surface-bound non-structural 1 (ns1) protein of influenza virus a h5n1 on lactobacillus casei strain c1. | the study aimed to construct a recombinant lactobacillus casei (l. casei) expressing the non-structural (ns) 1 protein of influenza a virus h5n1 on its cell wall. the ns1 gene was first amplified and fused to the psganc332 expression plasmid. the ns1 protein expression was carried out by l. casei strain c1. pcr screening and dna sequencing confirmed the presence of recombinant psg-ns1-anc332 plasmid in l. casei. the plasmid was stably maintained (98.94±1.65%) by the bacterium within the first 20 ... | 2017 | 28370088 |
visualization of consensus genome structure without using a reference genome. | standard graphical tools for whole genome comparison require a reference genome. however, any reference is also subject to annotation biases and rearrangements, and may not serve as the standard except for those of extensively studied model species. to fully exploit the rapidly accumulating sequence data from the recent sequencing technologies, genome comparison without any reference has been anticipated. | 2017 | 28361716 |
utility of thermostable xylanases of mycothermus thermophilus in generating prebiotic xylooligosaccharides. | xylooligosaccharides as emerging prebiotics are able to promote the growth of probiotic bacteria. in the present study, four neutral, thermostable xylanases (mtxyn11a, mtxyn11at, mtxyn11b, and mtxyn11c) from compost fungus mycothermus thermophilus cgmcc3.18119 were overexpressed in pichia pastoris gs115 and used to produce xylooligosaccharides from beechwood xylan. the enzymes showed similar enzymatic properties (maximal activities at ph 6.0-6.5 and 65 °c) but varied in catalytic efficiency and ... | 2017 | 28067041 |
biosorption of silver cations onto lactococcus lactis and lactobacillus casei isolated from dairy products. | the current work deals with the phenomenon of silver cations uptake by two kinds of bacteria isolated from dairy products. the mechanism of sorption of silver cations by lactococcus lactis and lactobacillus casei bacteria was investigated. inductively coupled plasma-mass spectrometry (icp-ms) was used for determination of silver concentration sorbed by bacteria. analysis of charge distribution was conducted by diffraction light scattering method. changes in the ultrastructure of lactococcus lact ... | 2017 | 28362838 |
rapid quantification of live/dead lactic acid bacteria in probiotic products using high-sensitivity flow cytometry. | a laboratory-built high-sensitivity flow cytometer (hsfcm) was employed for the rapid and accurate detection of lactic acid bacteria (lab) and their viability in probiotic products. lab were stained with both the cell membrane-permeable syto 9 green-fluorescent nucleic acid stain and the red-fluorescent nucleic acid stain, propidium iodide, which penetrates only bacteria with compromised membranes. the side scatter and dual-color fluorescence signals of single bacteria were detected simultaneous ... | 2017 | 28357994 |
growth performance and feed utilization of keureling fish tor tambra (cyprinidae) fed formulated diet supplemented with enhanced probiotic. | background the objective of the present study was to determine the optimum dosage of probiotic in the diet of keureling fish ( tor tambra) fry. methodslactobacillus casei from yakult® was used as a starter, and enhanced with curcuma xanthorrhiza, kaempferia galanga and molasses. the mixture was fermented for 7 days prior to use as probiotic in a formulated diet containing 30% crude protein. four levels of probiotic dosage; 0 ml kg (-1) (control), 5 ml kg (-1), 10 ml kg (-1) and 15 ml kg (-1) wer ... | 2017 | 28357045 |
effects of probiotic supplementation on lipid profile of women with rheumatoid arthritis: a randomized placebo-controlled clinical trial. | background: probiotics are live beneficial microorganisms which may exert hypolipidemic effects through many mechanisms. lipid profile disturbances are frequently reported in rheumatoid arthritis (ra) patients. the objective of this study was to evaluate the effects of lactobacillus casei on serum lipids of ra women. methods: in the present parallel randomized double-blind placebo-controlled clinical trial, 60 ra patients were recruited and divided into 2 groups. they received either a daily cap ... | 2017 | 28326290 |
contribution of sortase srta2 to lactobacillus casei bl23 inhibition of staphylococcus aureus internalization into bovine mammary epithelial cells. | probiotics have been considered as a promising strategy to prevent various diseases in both humans and animals. this approach has gained interest in recent years as a potential means to control bovine mastitis. in a previous study, we found that several l. casei strains, including bl23, were able to inhibit the internalization of s. aureus, a major etiologic agent of mastitis, into bovine mammary epithelial cells (bmec). this antagonism required a direct contact between l. casei and bmec or s. a ... | 2017 | 28323870 |
neonatal mono-colonization of germ-free mice with lactobacillus casei enhances casein immunogenicity after oral sensitization to cow's milk. | food allergy is an increasing global health problem and perinatal administration of probiotic bacteria is currently under investigation in order to prevent the development of allergic diseases. here, we investigated the impact of neonatal mono-colonization of mice with lactobacillus casei bl23 on an oral sensitization to cow's milk. | 2017 | 28318108 |
protective effect of lactobacillus casei on dmh-induced colon carcinogenesis in mice. | the administration of probiotics is a promising approach to reduce the prevalence of colon cancer, a multifactorial disease, with hereditary factors, as well as environmental lifestyle-related risk factors. biogenic polyamines, putrescine, spermidine, and spermine are small cationic molecules with great roles in cell proliferation and differentiation as well as regulation of gene expression. ornithine decarboxylase is the first rate-limiting enzyme for polyamine synthesis, and upregulation of or ... | 2017 | 28316010 |
isolated talonavicular joint tuberculosis in a child - rare location of koch's bacillus: a case report. | tuberculosis of the foot is an uncommon entity and the reported incidence is 0.1% to 0.3%. the isolated tuberculosis of talonavicular joint is exceptionally rare. in tuberculosis of the foot and ankle, the presentation is usually nonspecific. the diagnosis of tuberculosis affecting foot is difficult, especially when it is isolated. in doubtful cases, diagnosis should be confirmed by histopathological examination. unlike pulmonary kochs, osteoarticular tuberculosis should be treated with antitube ... | 2017 | 28293055 |
influence of synbiotics on selected oxidative stress parameters. | the aim of the present study was to assess synbiotic (lactobacillus casei + inulin) influence on oxidative stress parameters such as concentrations of malondialdehyde (mda), hydrogen peroxide (h2o2), glutathione, and free sulfhydryl groups content. experiments were carried out on healthy volunteers (n = 32). the subjects were divided into women group (n = 16) and men group (n = 16) and randomly assigned to synbiotic and control groups. blood samples were collected before synbiotic supplementatio ... | 2017 | 28286605 |
lactobacillus casei rhamnosus lcr35 in the management of functional constipation in children: a randomized trial. | to assess the effectiveness of lactobacillus casei rhamnosus lcr35 (lcr35) in the management of functional constipation in children. | 2017 | 28284477 |
defatted coconut residue crude polysaccharides as potential prebiotics: study of their effects on proliferation and acidifying activity of probiotics in vitro. | this paper reports on the extraction, partial characterization and the potential application of crude polysaccharides from defatted coconut residue as a prebiotic. the coconut residue was defatted and extracted to obtain the crude polysaccharides and its physicochemical properties were determined. the crude polysaccharides were assessed for monosaccharide composition, total carbohydrate content, reducing sugar concentration and protein content determination. the functional group and structural e ... | 2017 | 28242914 |
genetic, enzymatic and metabolite profiling of the lactobacillus casei group reveals strain biodiversity and potential applications for flavour diversification. | the lactobacillus casei group represents a widely explored group of lactic acid bacteria, characterized by a high level of biodiversity. in this study, the genetic and phenotypic diversity of a collection of more than 300 isolates of the lact. casei group and their potential to produce volatile metabolites important for flavour development in dairy products, was examined. | 2017 | 28199757 |
evolved distal tail carbohydrate binding modules of lactobacillus phage j-1: a novel type of anti-receptor widespread among lactic acid bacteria phages. | bacteriophage replication requires specific host-recognition. some siphophages harbour a large complex, the baseplate, at the tip of their non-contractile tail. this baseplate holds receptor binding proteins (rbps) that can recognize the host cell-wall polysaccharide (cwps) and specifically attach the phage to its host. while most phages possess a dedicated rbp, the phage j-1 that infects lactobacillus casei seemed to lack one. it has been shown that the phage j-1 distal tail protein (dit) plays ... | 2017 | 28196397 |
chemical characterization and immunomodulatory properties of polysaccharides isolated from probiotic lactobacillus casei lock 0919. | 2017 | 28177465 | |
mg(2+) improves the thermotolerance of probiotic lactobacillus rhamnosus gg, lactobacillus casei zhang and lactobacillus plantarum p-8. | food-related carbohydrates and proteins are often used as thermoprotectants for probiotic lactobacilli during industrial production and processing. however, the effect of inorganic salts is rarely reported. magnesium is the second-most abundant cation in bacteria, and commonly found in various foods. mg(2+) homeostasis is important in salmonella and has been reported to play a critical role in their thermotolerance. however, the role of mg(2+) in thermotolerance of other bacteria, in particular ... | 2017 | 28100014 |
antioxidant and antiproliferative potential of biosurfactants isolated from lactobacillus casei and their anti-biofilm effect in oral staphylococcus aureus strains. | biosurfactants also called bioemulsifiers are amphipathic compounds produced by many microorganisms that allow them to exhibit a wide range of biological activities. the aim of this study was to determine the antioxidant and antiproliferative potential of biosurfactants isolated from lactobacillus casei and to assess their anti-adhesive and anti-biofilm abilities against oral opportunistic staphylococcus aureus strains. the antioxidant activity of biosurfactant was evaluated using the in vitro s ... | 2017 | 28087493 |
properties of ice-cream fortified with zinc and lactobacillus casei. | in this study, the possible effects of zinc on physicochemical properties of ice cream and the survival of lactobacillus casei during a 90 days storage at -18°c was investigated. | 2017 | 28071014 |
chitosan incorporated in a total-etch adhesive system: antimicrobial activity against streptococcus mutans and lactobacillus casei. | the aim of this study was to investigate the antimicrobial effect of an experimental adhesive system containing chitosan (0.2% and 0.5%) against streptococcus mutans and lactobacillus casei. twenty-four extracted human third molars were used, and 4 cavities were prepared in each tooth. the teeth were contaminated with either s mutans (n = 12 teeth, 48 cavities) or l casei (n = 12 teeth, 48 cavities) microorganisms. one cavity in each tooth received 1 of the following treatments: negative control ... | 2017 | 28068269 |
the effect of lactobacillus isolates on growth performance, immune response, intestinal bacterial community composition of growing rex rabbits. | the objective of this experiment was to investigate the effect of lactobacillus isolates on intestinal bacterial community composition of growing rex rabbits. a total of 120 weaned rex rabbits (30 days old, 30 per group) were used for the experiment, which started after an adaptation period of 7 days. the control group was fed with basal diet only, while the treatment i, ii and iii groups were fed with basal diet adding antibiotics, lactobacillus zeae (lb1) and lactobacillus casei (l3) respectiv ... | 2017 | 28066944 |
aerobic metabolism in the genus lactobacillus: impact on stress response and potential applications in the food industry. | this review outlines the recent advances in the knowledge on aerobic and respiratory growth of lactic acid bacteria, focusing on the features of respiration-competent lactobacilli. the species of the genus lactobacillus have been traditionally classified as oxygen-tolerant anaerobes, but it has been demonstrated that several strains are able to use oxygen as a substrate in reactions mediated by flavin oxidases and, in some cases, to synthesize a minimal respiratory chain. the occurrence of genes ... | 2017 | 28063197 |
network meta-analysis of probiotics to prevent respiratory infections in children and adolescents. | probiotics have emerged as a promising intervention for the prevention of respiratory tract infections (rtis) in children. assess the effect of probiotics on prevention of rtis in children and adolescents. medline, embase, lilacs, scielo, cinahl, scopus, and web of science. key words: "respiratory tract infections" and probiotics. randomized controlled trials rct assessing the effect of probiotics on rtis in children and adolescents were included. two reviewers, working independently, to identif ... | 2017 | 28052594 |
recovery of lactobacillus casei strain shirota (lcs) from the intestine of healthy vietnamese adults after intake of fermented milk. | to demonstrate the gastrointestinal survival of lactobacillus casei strain shirota (lcs) in healthy vietnamese adults, a fermented milk drink containing lcs was administered daily for 14 days. twenty-six healthy vietnamese adults took part in the study. each participant consumed 65 ml of a fermented milk drink containing lcs daily for 14 days. the drink contained a dose of 10 8 cfu/ml lcs. fecal samples were collected before, during and after consuming the fermented milk drink. lcs was confirmed ... | 2017 | 28049264 |
heme derived from corynebacterium glutamicum: a potential iron additive for swine and an electron carrier additive for lactic acid bacterial culture. | to investigate the potential applications of bacterial heme, aminolevulinic acid synthase (hema) was expressed in a corynebacterium glutamicum ha strain that had been adaptively evolved against oxidative stress. the red pigment from the constructed strain was extracted and it exhibited the typical heme absorbance at 408 nm from the spectrum. to investigate the potential of this strain as an iron additive for swine, a prototype feed additive was manufactured in pilot scale by culturing the strain ... | 2017 | 28035120 |
losartan attenuates the coronary perivasculitis through its local and systemic anti-inflammatory properties in a murine model of kawasaki disease. | kawasaki disease is a common systemic vasculitis that leads to coronary artery lesions. besides its antihypertensive effects, losartan can modulate inflammation in cardiovascular disease. we examined whether losartan can attenuate coronary inflammation in a murine model of kawasaki disease. | 2017 | 27997528 |
survival and growth of probiotic lactic acid bacteria in refrigerated pickle products. | we examined 10 lactic acid bacteria that have been previously characterized for commercial use as probiotic cultures, mostly for dairy products, including 1 pediococcus and 9 lactobacilli. our objectives were to develop a rapid procedure for determining the long-term survivability of these cultures in acidified vegetable products and to identify suitable cultures for probiotic brined vegetable products. we therefore developed assays to measure acid resistance of these cultures to lactic and acet ... | 2017 | 27984668 |
tween 80 and respiratory growth affect metabolite production and membrane fatty acids in lactobacillus casei n87. | to evaluate the effect of cultivation (anaerobiosis vs respiration) and tween 80 supplementation on the production of metabolites and on the composition of membrane fatty acids (fas) in lactobacillus casei n87. | 2017 | 27981716 |
a novel rhamnose-rich hetero-exopolysaccharide isolated from lactobacillus paracasei dg activates thp-1 human monocytic cells. | lactobacillus paracasei dg is a bacterial strain with recognized probiotic properties and is used in commercial probiotic products. however, the mechanisms underlying its probiotic properties are mainly unknown. in this study, we tested the hypothesis that the ability of strain dg to interact with the host is at least partly associated with its ability to synthesize a surface-associated exopolysaccharide (eps). comparative genomics revealed the presence of putative eps gene clusters in the dg ge ... | 2017 | 27913418 |
habitual intake of fermented milk products containing lactobacillus casei strain shirota and a reduced risk of hypertension in older people. | this study investigated relationships between the frequent intake of fermented milk products containing lactobacillus casei strain shirota (lcs) and the onset of hypertension (resting systemic pressure ≥140 mmhg [systolic]/≥90 mmhg [diastolic], a doctor's diagnosis and/or antihypertensive medicine use) during a 5-year period in 352 communityliving japanese aged 65 to 93 years (125 men and 227 women). initially normotensive subjects were divided into two groups (n=254 and n=98) on the basis of th ... | 2017 | 27903092 |
the potential of species-specific tagatose-6-phosphate (t6p) pathway in lactobacillus casei group for galactose reduction in fermented dairy foods. | residual lactose and galactose in fermented dairy foods leads to several industrial and health concerns. there is very little information pertaining to manufacture of fermented dairy foods that are low in lactose and galactose. in the present study, comparative genomic survey demonstrated the constant presence of chromosome-encoded tagatose-6-phosphate (t6p) pathway in lactobacillus casei group. lactose/galactose utilization tests and β-galactosidase assay suggest that pts(gal) system, pts(lac) ... | 2017 | 27889146 |
target identification of volatile metabolites to allow the differentiation of lactic acid bacteria by gas chromatography-ion mobility spectrometry. | the purpose of this work was to study the potential of gas chromatography-ion mobility spectrometry (gc-ims) to differentiate lactic acid bacteria (lab) through target identification and fingerprints of volatile metabolites. the lab selected were used as reference strains for their influence in the flavour of cheese. the four strains of lab can be distinguished by the fingerprints generated by the volatile organic compounds (vocs) emitted. 2-butanone, 2-pentanone, 2-heptanone and 3-methyl-1-buta ... | 2017 | 27855912 |
transformation kinetics of fermented milk using lactobacillus casei (lc1) and streptococcus thermophilus: comparison of results with other inocula. | probiotic-based starter cultures are generally used to produce fermented milks with improved characteristics in the final product. in this study, lactobacillus casei and streptococcus thermophilus (lc1-st) were used as the starter inoculum. the transformation kinetics and properties of the final product were compared with systems produced with other inocula. the lc1-st inoculum delayed the production of lactic acid from 40 to 70 min (depending on temperature and concentration) when compared to l ... | 2017 | 27821208 |
a comparison of methods for extracting plasmids from a difficult to lyse bacterium: lactobacillus casei. | there are few practical protocols to extract efficient plasmid dna from the difficult-to-lyse bacterium, lactobacillus casei. this is related to production of a large amount of exopolysaccharide coat and its special physiological characteristics. in this study, we optimized a protocol to extract efficient plasmid dna from a recombinant l. casei strain. different extraction methods were evaluated in three classes of conventional, kit-based, and combined protocols. the quantity and quality of the ... | 2017 | 27816388 |
preventive effect of gardenia jasminoides on hcl/ethanol induced gastric injury in mice. | the therapeutic effect on hcl/ethanol induced gastric injury of gardenia jasminoides (jxgj-1 and jxgj-2) were determined by a animal model. jxgj-2 group reduced area of its gastric injury as compared to the control group, jxgj-2 also helped in decreasing the gastric secretion volume results raised in ph value. the no contents in serum, heart, liver, kidney and stomach of jxgj-2 group were more than jxgj-1 and control groups. jxgj-2 reduce cytokine levels as compared to jxgj-1 and control group. ... | 2017 | 27435384 |
short communication: improving the activity of bile salt hydrolases in lactobacillus casei based on in silico molecular docking and heterologous expression. | bile salt hydrolase (bsh) plays an essential role in the cholesterol-removing effect of lactic acid bacteria, which hydrolyze conjugated bile salts to amino acid and deconjugated bile salts. however, lactobacillus casei lacks the bsh gene, which may make it highly sensitive to bile salt stress. we wanted to improve the bsh activity of l. casei for various food-industry applications (e.g., milk fermentation). plate assay testing indicated that lactobacillus plantarum ar113 has the highest bsh act ... | 2017 | 28012620 |
human milk and mucosal lacto- and galacto-n-biose synthesis by transgalactosylation and their prebiotic potential in lactobacillus species. | lacto-n-biose (lnb) and galacto-n-biose (gnb) are major building blocks of free oligosaccharides and glycan moieties of glyco-complexes present in human milk and gastrointestinal mucosa. we have previously characterized the phospho-β-galactosidase gnbg from lactobacillus casei bl23 that is involved in the metabolism of lnb and gnb. gnbg has been used here in transglycosylation reactions, and it showed the production of lnb and gnb with n-acetylglucosamine and n-acetylgalactosamine as acceptors, ... | 2017 | 27714445 |
cd8+ t cells contribute to the development of coronary arteritis in the lactobacillus casei cell wall extract-induced murine model of kawasaki disease. | kawasaki disease (kd) is the leading cause of acquired heart disease among children in developed countries. coronary lesions in kd in humans are characterized by an increased presence of infiltrating cd3+ t cells; however, the specific contributions of the different t cell subpopulations in coronary arteritis development remain unknown. therefore, we sought to investigate the function of cd4+ and cd8+ t cells, treg cells, and natural killer (nk) t cells in the pathogenesis of kd. | 2017 | 27696768 |
probiotic mixture supplementation in the preventive management of trinitrobenzenesulfonic acid-induced inflammation in a murine model. | inflammatory bowel diseases (ibd) are characterized by inflammatory conditions of the intestine. probiotic bacteria (pb) can have beneficial effects in several gastrointestinal disorders. the objectives of this study were: (i) to provide an acute experimental ibd model induced by 2,4,6-trinitrobenzenesulfonic acid (tnbs) in cd-1 mice, and (ii) to assess the preventive effects of citogenex (lactobacillus casei and bifidobacterum lactis) supplementation on intestinal tissues and microbiota. mice w ... | 2017 | 27655518 |
eugenia uniflora dentifrice for treating gingivitis in children: antibacterial assay and randomized clinical trial. | school-age children are frequently at high risk for the onset of biofilm-dependent conditions, including dental caries and periodontal diseases. the objective of this study was to evaluate the clinical efficacy of a dentifrice containing eugenia uniflora linn. (surinam cherry) extract versus a triclosan-based comparator in treating gingivitis in children aged 10-12 years. the in vitro antibacterial potential of the dentifrice was tested against oral pathogens (streptococcus mutans, streptococcus ... | 2017 | 27652698 |
potential efficacy of lactobacillus casei ibrc_m10711 on expression and activity of insulin degrading enzyme but not insulin degradation. | type 2 diabetes (t2d) is a condition with insufficient insulin production or in the setting of insulin resistance with many origins including intestinal microbiota-related molecular mechanism. insulin-degrading enzyme (ide) is responsible for insulin breakdown in various tissues and is known as a potential drug target for t2d. here, we assessed the effects of cell-free supernatant (cfs) and uv-killed lactobacillus casei ibrc_m10711 on ide expression, ide activity, and insulin degradation in caco ... | 2017 | 27573410 |
bio-transformation of selenium in se-enriched bacterial strains of lactobacillus casei. | selenium is an element of very great importance for the proper functioning of the human body, mainly due to its antioxidant properties. selenium exhibits a preventive effect in the case of cardiovascular disease, the immune system, male infertility and inhibits the toxic action of other agents. selenium is important for hashimoto's disease. intake of selenium in the diet slows the aging process. the biological and toxicological effects of selenium strongly depend on its chemical form. some organ ... | 2017 | 27546322 |
the use of date waste for lactic acid production by a fed-batch culture using lactobacillus casei subsp. rhamnosus. | the production of lactic acid from date juice by lactobacillus caseisubsp. rhamnosus in batch and fed-batch cultures has been investigated. the fed-batch culture system gave better results for lactic acid production and volumetric productivity. the aim of this work is to determine the effects of the feeding rate and the concentration of the feeding medium containing date juice glucose on the cell growth, the consumption of glucose and the lactic acid production by lactobacillus casei subsp. rham ... | 2017 | 26413076 |
daily intake of fermented milk with lactobacillus casei strain shirota reduces the incidence and duration of upper respiratory tract infections in healthy middle-aged office workers. | although several studies have demonstrated the efficacy of probiotics for preventing upper respiratory tract infections (urtis) in at-risk populations, including children and the elderly, few studies have investigated the efficacy of probiotics in healthy adults living normal, everyday lives. thus, we tried to evaluate the effects of lactobacillus casei strain shirota-fermented milk (lcs-fm) on the incidence of urtis in healthy middle-aged office workers. | 2017 | 26419583 |
estimation of the antioxidant activity of the commercially available fermented milks. | free radicals are connected with the increased risk of certain diseases, especially cancers. there is some scientific evidence that antioxidant-rich diet may inhibit the negative impact of free radicals. the aim of the present study was to analyse the antioxidant capacity of the selected commercial natural and flavoured fermented milks offered in poland, derived from different producers. | 2017 | 28068044 |
effects of probiotic supplementation on oxidative stress indices in women with rheumatoid arthritis: a randomized double-blind clinical trial. | rheumatoid arthritis (ra) is an autoimmune inflammatory disease that causes great pain and disability and increasing oxidative stress in patients. the objective of the present study was to evaluate the effects of probiotics-live microorganisms with many health benefits, including antioxidant properties-on oxidative stress indices of patients with ra. this study is a secondary analysis from a previously published study methods: in a randomized double-blind placebo-controlled clinical trial, 46 pa ... | 2017 | 25856220 |
proline iminopeptidase pepi overexpressing lactobacillus casei as an adjunct starter in edam cheese. | in this study the growth of genetically modified lactobacillus casei lab6, overexpressing proline iminopeptidase pepi and its capacity to increase free proline was investigated during ripening of edam cheese. the strain successfully survived 12 weeks of ripening period in cheese. the food-grade plasmid pleb604, carrying the pepi gene, was stable, and pepi enzyme was active in lab6 cells isolated at different stages of the ripening process. however, hplc analyses indicated that lb. casei lab6 cou ... | 2017 | 23851577 |
multiple microbial cell-free extracts improve the microbiological, biochemical and sensory features of ewes' milk cheese. | this study used cell-free enzyme (cfe) extracts from lactobacillus casei, hafnia alvei, debaryomyces hansenii and saccharomyces cerevisiae to condition or accelerate pecorino-type cheese ripening. compositional, microbiological, and biochemical analyses were performed, and volatile and sensory profiles were obtained. lactobacilli and cocci increased during ripening, especially in cheeses containing cfe from l. casei, h. alvei and d. hansenii (lhd-c) and l. casei, h. alvei and s. cerevisiae (lhs- ... | 2017 | 28576361 |
the individual contribution of starter and non-starter lactic acid bacteria to the volatile organic compound composition of caciocavallo palermitano cheese. | the contribution of two starter (lactobacillus delbrueckii and streptococcus thermophilus) and nine non-starter (enterococcus casselliflavus, enterococcus faecalis, enterococcus durans, enterococcus gallinarum, lactobacillus casei, lactobacillus paracasei, lactobacillus rhamnosus, pediococcus acidilactici and pediococcus pentosaceus) species of lactic acid bacteria (lab) to the volatile organic compounds (vocs) of caciocavallo palermitano cheese was investigated. the strains used in this study w ... | 2017 | 28783535 |
lactic acid bacteria involved in cocoa beans fermentation from ivory coast: species diversity and citrate lyase production. | microbial fermentation is an indispensable process for high quality chocolate from cocoa bean raw material. lactic acid bacteria (lab) are among the major microorganisms responsible for cocoa fermentation but their exact role remains to be elucidated. in this study, we analyzed the diversity of lab in six cocoa producing regions of ivory coast. ribosomal 16s gene sequence analysis showed that lactobacillus plantarum and leuconostoc mesenteroides are the dominant lab species in these six regions. ... | 2017 | 28578265 |
biosynthesis of silver nanoparticles on orthodontic elastomeric modules: evaluation of mechanical and antibacterial properties. | in the present study, silver nanoparticles (agnps) were synthesized in situ on orthodontic elastomeric modules (oem) using silver nitrate salts as metal-ion precursors and extract of the plant hetheroteca inuloides (h. inuloides) as bioreductant via a simple and eco-friendly method. the synthesized agnps were characterized by uv-visible spectroscopy; scanning electron microscopy-energy-dispersive spectroscopy (sem-eds) and transmission electron microscopy (tem). the surface plasmon resonance pea ... | 2017 | 28841178 |
development of a counterselectable seamless mutagenesis system in lactic acid bacteria. | lactic acid bacteria (lab) are receiving more attention to act as cell factories for the production of high-value metabolites. however, the molecular tools for genetic modifying these strains are mainly vector-based double-crossover strategies, which are laborious and inefficient. to address this problem, several counterselectable markers have been developed, while few of them could be used in the wild-type host cells without pretreatment. | 2017 | 28679374 |
the malate sensing two-component system maekr is a non-canonical class of sensory complex for c4-dicarboxylates. | microbial colonization of different environments is enabled to a great extent by the plasticity of their sensory mechanisms, among them, the two-component signal transduction systems (tcs). here, an example of tcs plasticity is presented: the regulation of l-malate catabolism via malic enzyme by maerk in lactobacillales. maekr belongs to the citrate family of tcs as the escherichia coli dcusr system. we show that the lactobacillus casei histidine-kinase maek is defective in autophosphorylation a ... | 2017 | 28577341 |
genome adaptive evolution of lactobacillus casei under long-term antibiotic selection pressures. | the extensive use of antibiotics in medicine has raised serious concerns about biosafety. however, the effect of antibiotic application on the adaptive evolution of microorganisms, especially to probiotic bacteria, has not been well characterized. thus, the objective of the current work was to investigate how antibiotic selection forces might drive genome adaptation using lactobacillus (l.) casei zhang as a model. | 2017 | 28438179 |
lactobacillus casei regulates differentiation of th17/treg cells to reduce intestinal inflammation in mice. | in order to study the ability of lactobacillus casei to ameliorate murine enteritis, 18 mice were randomly divided into 3 groups: the enteritis group, intervention group, and control group. the interleukin (il)-6 and transforming growth factor-β (tgf)-β content in mouse peripheral blood and duodenum was detected using an enzyme-linked immunosorbent assay (elisa). the number of cd4(+)cd25(+)foxp3(+) t-regulatory cells (tregs) and cd4(+)il-17a(+) th17 cells in the mesenteric lymph nodes (mln) and ... | 2017 | 28408780 |
effect of lactobacillus on body weight and body fat in overweight subjects: a systematic review of randomized controlled clinical trials. | gut microbiota is important for maintaining body weight. modulation of gut microbiota by probiotics may result in weight loss and thus help in obesity treatment. the aim of this systematic review was to evaluate the effects of lactobacillus on weight loss and/or fat mass in overweight adults. a search was performed on the medline (pubmed) and scopus electronic databases using the search terms: 'probiotics', 'lactobacillus, 'obesity', 'body weight changes', 'weight loss', 'overweight', 'abdominal ... | 2017 | 28792488 |
effects of 4 probiotic strains in coculture with traditional starters on the flavor profile of yogurt. | to study the influence of probiotics on the flavor profile of yogurt, 4 probiotics, including lactobacillus acidophilus, lactobacillus plantarum, lactobacillus rhamnosus, and lactobacillus casei, were cofermented with traditional starters. the changes of bacterial growth, acid contents and volatile compounds of yogurt were investigated during fermentation and refrigerated storage. the strains that exhibited a low growth rate in milk did not significantly affect the bacterial population dynamics, ... | 2017 | 28598540 |
effect of probiotic lactobacilli on the growth of streptococcus mutans and multispecies biofilms isolated from children with active caries. | background the purpose of this investigation was to evaluate the effect of probiotic lactobacilli on streptococcus mutans (ms) and multispecies biofilms isolated from children with severe caries. material and methods twenty children with active caries (dmfs ≥6) were selected as the experimental group and streptococcus mutans (ms) were isolated from their saliva. after identification the ms strains were mixed with lactobacilli at 37°c, following which viable ms colonies were counted. at the same ... | 2017 | 28851857 |
large-scale phylogenomics of the lactobacillus casei group highlights taxonomic inconsistencies and reveals novel clade-associated features. | although the genotypic and phenotypic properties of the lactobacillus casei group have been studied extensively, the taxonomic structure has been the subject of debate for a long time. here, we performed a large-scale comparative analysis by using 183 publicly available genomes supplemented with a lactobacillus strain isolated from the human upper respiratory tract. on the basis of this analysis, we identified inconsistencies in the taxonomy and reclassified all of the genomes according to their ... | 2017 | 28845461 |
microbial diversity of commercial makgeolli and its influence on the organoleptic characteristics of korean rice sourdough, jeung-pyun. | sourdough is made by fermentation of dough by lactic acid bacteria (lab) and yeast to improve bread properties like volume, flavor, and texture. a korean traditional sourdough was made by fermenting rice flour with rice wine (makgeolli) and used to make sponge-like bread (jeung-pyun). the aim of this study was to investigate the microbial diversity of makgeolli products and their influence on the organoleptic quality of jeung-pyun. three commercial makgeolli were tested for jeung-pyun production ... | 2017 | 28813780 |
development of a transient muts-based hypermutation system for adaptive evolution of lactobacillus casei to low ph. | this study explored transient inactivation of the gene encoding the dna mismatch repair enzyme muts as a tool for adaptive evolution of lactobacillus casei muts deletion derivatives of l. casei 12a and atcc 334 were constructed and subject to a 100-day adaptive evolution process to increase lactic acid resistance at low ph. wild-type parental strains were also subject to this treatment. at the end of the process, the δmuts lesion was repaired in representative l. casei 12a and atcc 334 δmuts iso ... | 2017 | 28802267 |
probiotics protect mice from cocrmo particles-induced osteolysis. | wear particle-induced inflammatory osteolysis is the primary cause of aseptic loosening, which is the most common reason for total hip arthroplasty (tha) failure in the med- and long term. recent studies have suggested an important role of gut microbiota (gm) in modulating the host metabolism and immune system, leading to alterations in bone mass. probiotic bacteria administered in adequate amounts can alter the composition of gm and confer health benefits to the host. given the inflammatory ost ... | 2017 | 28794630 |
chemometric evaluation of the volatile profile of probiotic melon and probiotic cashew juice. | the aim of this study was to evaluate the influence of the lactic acid fermentation on volatile compounds of melon and cashew apple juices. the effect of the fermentation processing on the volatile profile of probiotic juices was assessed by hs-spme/gc-ms coupled to chemometrics with 67.9% and 81.0% of the variance in the first principal component for melon and cashew juices, respectively. the lactobacillus casei fermentation imparted a reduction of ethyl butanoate, ethyl-2-methylbutirate, and e ... | 2017 | 28784506 |
lactobacillus casei ccfm419 attenuates type 2 diabetes via a gut microbiota dependent mechanism. | probiotics, as dietary supplements, transmit their major effects through the regulation of gut microbiota. according to a previous study, one possible mechanism of lactobacillus casei ccfm419 protection against diabetes may involve gut flora. to test this hypothesis, high fat and streptozotocin-induced c57bl/6j mice were fed l. casei ccfm419 at 10(8), 10(9), and 10(10) colony forming units (cfu). compared to untreated mice, 10(9) cfu of l. casei ccfm419 attenuated several symptoms of diabetes, i ... | 2017 | 28782784 |
a fast pcr-based method for the characterization of prophage profiles in strains of the lactobacillus casei group. | lysogeny is widespread among lactobacillus strains of the casei group (l. casei, l. paracasei and l. rhamnosus), and prophages account for most strain-specific dna. numerous pcr based methods have been developed to detect free phages of lactic acid bacteria, but they do not take in consideration prophages. in this study, a new pcr method for the detection of lysogeny was developed using genome sequences of l. casei group strains (including bl23) and bacteriophages. nine pairs of primers were des ... | 2017 | 28757387 |
effects of intake of lactobacillus casei subsp. casei 327 on skin conditions: a randomized, double-blind, placebo-controlled, parallel-group study in women. | lactic acid bacteria are gut flora that play key roles in intestinal homeostasis, which may affect a variety of physiological functions. our preliminary double-blind, placebo-controlled, parallel-group trials have suggested that intake of heat-killed lactobacillus casei subsp. casei 327 (designated l. k-1) is effective for improving skin conditions. the aim of this study was to confirm the effect of l. k-1 intake in a randomized, double-blind, placebo-controlled, parallel-group study in healthy ... | 2017 | 28748132 |
metabolic gene-targeted monitoring of non-starter lactic acid bacteria during cheese ripening. | long ripened cheeses, such as grana padano (gp), a protected designation of origin (pdo) italian cheese, harbor a viable microbiota mainly composed of non-starter lactic acid bacteria (nslab), which contribute to the final characteristics of cheese. the nslab species lactobacillus rhamnosus, lb. casei and lb. paracasei are frequently found in gp, and form a closely related taxonomic group (lb. casei group), making it difficult to distinguish the three species through 16s rrna sequencing. spxb, a ... | 2017 | 28735145 |
the effect of probiotic lactobacillus casei shirota on knee osteoarthritis: a randomised double-blind, placebo-controlled clinical trial. | knee osteoarthritis (oa) treatment is challenging due to inefficacy and adverse effects of current medications. probiotic treatment has been shown to promote bone metabolism, reduce pain and inflammatory responses of age-related musculoskeletal disorders, including oa. we aimed to investigate the effect of probiotic lactobacillus casei shirota (lcs) on patients with knee oa. 537 patients with knee oa were enrolled in this double-blind, placebo-controlled trial, who were randomised to receive ski ... | 2017 | 28726510 |
effective identification of lactobacillus casei group species: genome-based selection of the gene mutl as the target of a novel multiplex pcr assay. | lactobacillus casei,lactobacillus paracasei and lactobacillusrhamnosus form a closely related taxonomic group (the l. casei group) within the facultatively heterofermentative lactobacilli. strains of these species have been used for a long time as probiotics in a wide range of products, and they represent the dominant species of nonstarter lactic acid bacteria in ripened cheeses, where they contribute to flavour development. the close genetic relationship among those species, as well as the simi ... | 2017 | 28721852 |
characterization of candidate probionts isolated from human breast milk. | this study was designed to isolate and identify the potential probionts present in 32 healthy mothers' breast milk. microbial culture media and 16srrna sequencing were used to isolate and identify the bacteria and all isolates were analyzed for their antagonistic potential, resistance to acidic ph, bile salts and survival under simulated gastric and intestinal conditions. the colonization potential was further assessed based on adherence to human enterocyte-like caco-2 cell lines. the breast mil ... | 2017 | 28719350 |
strains of the lactobacillus casei group show diverse abilities for the production of flavor compounds in 2 model systems. | cheese flavor development is directly connected to the metabolic activity of microorganisms used during its manufacture, and the selection of metabolically diverse strains represents a potential tool for the production of cheese with novel and distinct flavor characteristics. strains of lactobacillus have been proven to promote the development of important cheese flavor compounds. as cheese production and ripening are long-lasting and expensive, model systems have been developed with the purpose ... | 2017 | 28711258 |
high-quality draft genome sequence of lactobacillus casei strain z11, isolated from a human adult intestinal biopsy sample. | several lactobacillus casei strains are used as probiotics. l. casei strain z11, isolated from a human colon biopsy sample, has been suggested as a probiotic candidate based on promising properties in vitro here, we present a 2.74-mbp high-quality draft genome sequence for this strain. | 2017 | 28705981 |
investigation of the efficacy of synbiotics in the treatment of functional constipation in children: a randomized double-blind placebo-controlled study. | the aim of this study was to demonstrate the efficacy of synbiotic (lactobacillus casei, l. rhamnosus, l. plantarum, and bifidobacterium lactis and prebiotics [fiber, polydextrose, fructo-oligosaccharides, and galacto-oligosaccharides]) treatment in children with functional constipation. | 2017 | 28705786 |
direct and indirect measurements of enhanced phenolic bioavailability from litchi pericarp procyanidins by lactobacillus casei-01. | litchi pericarp procyanidins (lpp) are dietary supplements with high antioxidant activity, but poor oral bioavailability and efficacy. lactobacillus casei (l. casei-01) can transform flavan-3-ols from litchi pericarp and increase their antioxidant ability; thus, l. casei-01 with lpp was administered to rats for four and eight weeks to study the effect of such a combination on metabolic parameters and on phase ii metabolism and detoxification pathways in the liver as an indirect measure for pheno ... | 2017 | 28702654 |
anxiogenic effects of a lactobacillus, inulin and the synbiotic on healthy juvenile rats. | gut microbiota interventions, including probiotic and prebiotic use can alter behavior in adult animals and healthy volunteers. however, little is known about their effects in younger individuals. to investigate this, male sprague-dawley rats (post-natal day 21, pnd21) received lactobacillus casei 54-2-33 (10(4)cfu/ml), inulin as prebiotic (16mg/ml), or both together (synbiotic) via drinking water for 14days. control rats received water alone. open field (of) and elevated plus maze (epm) behavio ... | 2017 | 28694176 |
the viable but nonculturable state induction and genomic analyses of lactobacillus casei bm-lc14617, a beer-spoilage bacterium. | this study aimed to investigate the viable but nonculturable (vbnc) state and genomic features of a beer-spoilage strain, lactobacillus caseibm-lc14617. induction on the vbnc state of l. casei strain bm-lc14617 was conducted by both low-temperature storage and continuous passage in beer, and formation of vbnc state was detected after 196 ± 3.3 days and 32 ± 1.6 subcultures, respectively. resuscitation of vbnc cells was successfully induced by addition of catalase, and culturable, vbnc, and resus ... | 2017 | 28685978 |
prophylactic effects of secretion metabolites of dairy lactobacilli through downregulation of erbb-2 and erbb-3 genes on colon cancer cells. | colon cancer is one of the most prevalent cancers, and intestinal microbial community plays a pivotal role in colorectal tumor genesis. probiotics as live microorganisms may be able to exert an anticancer effect in colon cancer. the aim of this study was to isolate and identify lactobacillus spp. from traditional dairy products with probiotic properties and to investigate their anticancer effects through erbb-2 and erbb-3 gene expression in colon cancer cells. the isolated lactobacilli from yogu ... | 2017 | 28683007 |