Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
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| hepatitis b virus induced cytoplasmic antineutrophil cytoplasmic antibody-mediated vasculitis causing subarachnoid hemorrhage, acute transverse myelitis, and nephropathy: a case report. | transverse myelitis, subarachnoid hemorrhage, and nephropathy are established but rare complications of hepatitis b virus infection that can potentially be triggered by an antibody-mediated vasculitis as a result of a viral infection. the following is a case report detailing a patient presenting with all three of the above presentations who is cytoplasmic antineutrophil cytoplasmic antibody-positive and a chronic carrier of hepatitis b. | 2017 | 28366165 |
| [spontaneous remission of hcv infection after autologous stem cell transplantation in a 58-year-old man]. | we report about a 58-year-old man with a chronic and treatment-naive hepatitis c virus (hcv) infection of genotype 1b, who had undergone autologous stem cell transplantation twice due to multiple myeloma. subsequently, a high-level viremic reactivation of an occult hepatitis b virus (hbv) infection and also a reverse seroconversion was observed. furthermore, a sustained spontaneous remission of hcv infection was seen. antiviral therapy of hbv infection was initiated with tenofovir. seven months ... | 2017 | 28235985 |
| pancreas transplantation after liver transplantation: a case report. | our aim was to describe the clinical indications, surgical technique, and clinical outcomes of a pancreas transplantation, performed 4 years after liver transplantation, as treatment for new-onset, uncontrolled diabetes mellitus in a 53-year-old man. liver transplantation was performed for end-stage liver disease secondary to hepatitis b virus infection and hepatocellular carcinoma. the patient had no history of diabetes prior to the liver transplantation. the decision to proceed with a pancreas ... | 2017 | 28104144 |
| recurrent hepatitis b and d virus infection in a liver transplant recipient. | hepatitis b virus (hbv) and hepatitis delta virus (hdv) co-infections progress rapidly and lead to cirrhosis. in japan, the prevalence of hbv and hdv co-infected patients is low. therefore, there are few reports of patients with hbv and hdv co-infection having undergone liver transplantation. herein, we report a rare case of recurrence of hbv and hdv in a 41-year-old man who underwent living donor liver transplantation 4 years prior. | 2017 | 28104130 |
| a case of figurate urticaria by etanercept. | etanercept is a competitive inhibitor of tumor necrosis factor-alpha (tnf-α) a polypeptide hormone, involved in the development of the immune system, in host defense and immune surveillance. even if the etanercept mechanism of action is not completely understood, it is supposed that it negatively modulates biological responses mediated by molecules (cytokines, adhesion molecules, or proteinases) induced or regulated by tnf. for this reason, it is widely used in the treatment of immunologicals di ... | 2017 | 27440958 |
| tenofovir-induced fanconi syndrome in a patient with chronic hepatitis b monoinfection. | tenofovir disoproxil fumarate (tdf) is a nucleotide reverse transcriptase inhibitor indicated for treatment of patients with chronic hepatitis b virus (chb) and human immunodeficiency virus (hiv) infections. despite the good safety profile of the drug, fanconi syndrome is a possible adverse reaction of tdf treatment, especially in hiv-infected patients. only a few cases have been reported in patients with chb-monoinfections. this report presents a case of a 58-year-old man with mild hbeag-negati ... | 2017 | 26845606 |
| spontaneous regression of hepatocellular carcinoma: its imaging course leading to complete disappearance. | spontaneous regression of hepatocellular carcinoma (hcc) is a rare phenomenon. we followed a detailed clinical course of a spontaneous and complete disappearance of hcc during a short interval. a 73-year-old man with hepatitis b virus infection presented with a 15-mm mass in the right anterior superior segment of the liver. the mass was diagnosed as hcc by imaging findings. we found an elevated serum α-fetoprotein (afp) level of 748 ng/ml. the tumor regressed to 6 mm on imaging examination, and ... | 2017 | 25848359 |
| host and viral traits predict zoonotic spillover from mammals. | the majority of human emerging infectious diseases are zoonotic, with viruses that originate in wild mammals of particular concern (for example, hiv, ebola and sars). understanding patterns of viral diversity in wildlife and determinants of successful cross-species transmission, or spillover, are therefore key goals for pandemic surveillance programs. however, few analytical tools exist to identify which host species are likely to harbour the next human virus, or which viruses can cross species ... | 2017 | 28636590 |
| totally laparoscopic living donor right hepatectomy in a donor with trifurcation of bile duct. | donor operation in adult living donor liver transplantation is associated with significant postoperative morbidity. to avoid laparotomy wound complications and shorten postoperative recovery, laparoscopic liver graft harvest has been developed recently. however, to determine the cut point of bile duct is challenging. herein, we report the application of totally laparoscopic approach for right liver graft harvest in a donor with trifurcation of the bile duct. a19-year-old man volunteered for livi ... | 2016 | 26211878 |
| episodic fevers and vasodilatory shock mimicking urosepsis in a patient with hiv-associated multicentric castleman's disease: a case report. | multicentric castleman's disease (mcd) is a pre-malignancy that presents with lymphadenopathy and features of systemic inflammation. human immunodeficiency virus (hiv)-associated mcd is associated with human herpesvirus-8 (hhv-8) infection. if untreated mcd has a relapsing and remitting course that is eventually fatal. | 2016 | 26831502 |
| retransplant as rescue treatment for abo-compatible living-donor liver transplant related antibody-mediated rejection: a case report. | antibody-mediated rejection after liver transplant, especially when the donor is not a direct relative; it is associated with additional inconvenience for patients. we encountered a case in which antibody-mediated rejection because of de novo donor specific antibodies against donor human leukocyte antigen developed 6 months after abo-compatible living-donor liver transplant and was treated with retransplant. a 38-year-old man with hepatitis b virus-related hepatocellular carcinoma underwent livi ... | 2016 | 26742858 |
| hepatitis b surface antigen in oocytes and embryos may not result in vertical transmission to offspring of hepatitis b virus carriers. | to investigate the vertical transmission of hepatitis b virus (hbv) via embryos to children and whether hbv in embryos has an effect on the development of the fetus and pregnancy outcomes of in vitro fertilization and embryo transfer (ivf-et). | 2016 | 26730499 |
| gianotti-crosti syndrome associated with ebstein-barr virus and parvovirus b-19 coinfection in a male adult: case report and review of the literature. | gianotti-crosti syndrome (gcs) is a self-limiting, mostly childhood-appearing, cutaneous eruption with characteristic symmetric areal distribution. the original cases, described by gianotti in 1955, were associated with hepatitis b virus infection, but other viral and bacterial infections, as well as immunizations, have been implied in etiology of this condition. adult cases are rare and have been reported almost exclusively in women. we present the case of a 20-year-old caucasian man who had ty ... | 2016 | 25034095 |
| acute respiratory failure caused by hepatopulmonary fistula in a patient with hepatocellular carcinoma. | a 59-year-old man presented with acute dyspnea following sudden productive cough and expectoration of a full cup of "blood-tinged" sputum. he had been diagnosed with hepatitis b virus-related hepatocellular carcinoma and had received transarterial chemoembolization 5 years ago for a 20-cm hepatic mass; he denied any history of hematemesis and the last esophagogastroduodenoscopy from a year ago showed absence of varix. chest computed tomography (ct) with angiography showed new appearance of right ... | 2016 | 27433178 |
| physicochemical characterization of a polysaccharide fraction from platycladus orientalis (l.) franco and its macrophage immunomodulatory and anti-hepatitis b virus activities. | a polysaccharide fraction, here called pop1, was purified from the leaves of platycladus orientalis (l.) franco by water extraction and alcohol precipitation. physicochemical characterization indicated that pop1 had a relative molecular weight of 8.10 × 10(3) da and consisted of rhamnose (5.74%), arabinose (12.58%), mannose (10.97%), glucose (64.96%), and galactose (6.55%). the main linkage types of pop1 consisted of (1→5)-linked α-l-ara, (1→3)-linked α-l-man, (1→6)-linked β-l-rha, (1→4)-linked ... | 2016 | 27345527 |
| virus-associated haemophagocytic lymphohistiocytosis in a young filipino man. | haemophagocytic lymphohistiocytosis (hlh) is a rare syndrome of pathological immune activation characterised by extreme inflammation. we present a case of a young filipino man consulting for non-specific symptoms of fever, body malaise and weight loss. prominent physical examination findings included gross pallor, cachexia and hepatosplenomegaly. laboratory results revealed pancytopaenia, while bone marrow examination revealed haemophagocytosis. further workup for hlh showed hypertriglyceridaemi ... | 2016 | 27284096 |
| hepatitis b reactivation after ifosfamide therapy for retroperitoneal sarcoma. | patients receiving cancer treatment are at risk for hepatitis b virus (hbv) reactivation. ifosfamide is an alkylating agent and is considered to be one of the important drugs for the treatment of metastatic sarcoma. no association of ifosfamide and hbv reactivation has been reported so far. | 2016 | 27246626 |
| extremely elevated alpha-fetoprotein due to acute exacerbation of chronic hepatitis b without malignancy: a case report. | alpha-fetoprotein is produced by a variety of tumors such as hepatocellular carcinoma, hepatoblastoma, and germ cell tumors of the ovary and testes. however, we present a case of significantly elevated serum alpha-fetoprotein without evidence of malignant disease in a patient who is a carrier of chronic hepatitis b. | 2016 | 27246404 |
| living donor liver transplantation indicated for compensated liver cirrhosis with symptomatic gallstone diseases: report of two cases. | surgical interventions for symptomatic gallstone disease could be dangerous in patients with severe comorbid conditions including liver cirrhosis. here, we report our experience of living donor liver transplantation (ldlt) indicated for two patients with liver cirrhosis complicated with gallstone diseases. | 2016 | 27215224 |
| dually active hiv/hbv antiretrovirals as protection against incident hepatitis b infections: potential for prophylaxis. | hepatitis b virus (hbv) has a detrimental effect on human immunodeficiency virus (hiv) natural course, and hbv vaccination is less effective in the hiv infected. we examine the protective effect of dually active antiretroviral therapy (daart) for hiv/hbv (tenofovir, lamivudine, and emtricitabine) in a large cohort encompassing heterosexuals, men who have sex with men, and intravenous drug users who are hiv infected yet susceptible to hbv, with comprehensive follow-up data about risky behavior an ... | 2016 | 27190182 |
| hepatitis b virus reactivation following salazosulfapyridine monotherapy in a patient with rheumatoid arthritis. | a 72-year-old man was diagnosed with rheumatoid arthritis (ra) and prior hepatitis b virus (hbv) infection. he began treatment with salazosulfapyridine (sasp). several months later, his blood tests reflected a slightly elevated liver function. serum tests were positive for hepatitis b surface antigen and hbv-dna, and the diagnosis of de novo hbv hepatitis was made. a genetic analysis showed that he had polymorphisms of abcg2 and nat2, which could lead to high plasma concentrations of sasp and su ... | 2016 | 27181550 |
| fatal fulminant hepatitis caused by infection with subgenotype a1 hepatitis b virus with c1766t/t1768a core promoter mutations. | adults initially infected with the hepatitis b virus develop various types of hepatitis ranging from asymptomatic to fulminant, and the clinical course of infection is influenced by a variety of host and viral factors. the viral risk factors associated with fulminant hepatitis reportedly include subgenotype b1, negative hbe antigen, and mutations in the precore and core promoter regions. here, we present a case of fatal fulminant hepatitis caused by infection with subgenotype a1 hepatitis b viru ... | 2016 | 27165167 |
| alum: an old dog with new tricks. | aluminum compounds (alum) are the most widely used adjuvants in veterinary and human vaccines. alum was initially thought to be a simple depot for antigen retention; however, our understanding of the mechanism by which it works has progressed substantially in recent decades. nonetheless, consensus regarding its roles in different aspects of immune regulation has not been reached, and it remains a long-standing research subject in the field of vaccinology. this review, in chronological order, dis ... | 2016 | 27004761 |
| successful treatment for sorafenib-induced liver dysfunction: a report of case with liver biopsy. | sorafenib is an oral multikinase inhibitor with anti-proliferative and anti-angiogenic effects and is used worldwide for the treatment of advanced or metastatic hepatocellular carcinoma (hcc). while the significant survival benefit of sorafenib in patients with advanced hcc was demonstrated, various treatment-related adverse events might happen. of them, the incidence of drug-related severe liver dysfunction rarely occurs (<1 %) but is one of the serious adverse events by sorafenib. the authors ... | 2016 | 26943680 |
| a concise history of mycotoxin research. | toxigenic fungi and mycotoxins entered human food supplies about the time when mankind first began to cultivate crops and to store them from one season to the next, perhaps 10,000 years ago. the storage of cereals probably initiated the transition by mankind from hunter-gatherer to cultivator, at the same time providing a vast new ecological niche for fungi pathogenic on grain crops or saprophytic on harvested grain, many of which produced mycotoxins. grains have always been the major source of ... | 2016 | 27960261 |
| fulminant zygomycosis of graft liver following liver transplantation. | a 44-year-old man with hepatitis b virus (hbv)-related cirrhosis underwent living donor liver transplantation at our institute. induction of immunosuppression was achieved with basiliximab, due to deranged renal function, and maintained with prednisolone, tacrolimus and mycophenolate mofetil. the intraoperative and immediate postoperative periods were fairly uneventful. a duplex scan, taken during the third week post-transplantation due to sudden rise in liver enzymes, revealed multifocal hypoec ... | 2016 | 26873918 |
| selection of affinity-improved neutralizing human scfv against hbv pres1 from cdr3 vh/vl mutant library. | a cdr3 mutant library was constructed from a previously isolated anti-hbv neutralizing homo sapiens scfv-31 template by random mutant primers pcr. then the library was displayed on the inner membrane surface in escherichia coli periplasmic space. seven scfv clones were isolated from the mutant library through three rounds of screening by flow cytometry. competition elisa assay indicates that isolated scfv fragments show more efficient binding ability to hbv pres1 compared with parental scfv-31. ... | 2016 | 27255707 |
| human immunodeficiency virus and hepatitis b genotype g/a2 recombinant co-infection: a case study. | hepatitis b virus (hbv) genotypes have distinct geographical distributions and are associated with different clinical courses. hbv genotype g (hbv/g) is extremely rare among human immunodeficiency virus (hiv) infected populations in japan. genetic analysis and clinical course of recombinant forms with hbv/g infection are seldom reported in the literature. | 2016 | 27652075 |
| ulcerative colitis with hepatitis b virus infection treated successfully by granulocyte monocyte apheresis. | ulcerative colitis (uc) is a major type of idiopathic inflammatory bowel disease (ibd). immunosuppressive therapies are used to treat ibd patients. clinicians have strong concerns about using immunosuppressive therapies for ibd patients with hepatitis b virus (hbv) infection because aggressive immunosuppressive therapy can promote reactivation of hbv. for that reason, physicians hesitate to use steroids or other immunosuppressive drugs for ibd patients with hbv infection. granulocyte monocyte ap ... | 2016 | 26876484 |
| hepatitis b leading to megaloblastic anemia and catastrophic peripheral thrombocytopenia. | hepatitis b virus (hbv) typically causes chronic hepatitis, cirrhosis, and hepatocellular carcinoma. it is associated with a variety of extrahepatic complications. we herein, present a rare extrahepatic complication of hbv infection. a 32-year man presented with melena, bleeding from gums and fever. peripheral blood examination revealed anemia, macrocytosis and severe thrombocytopenia. his hepatitis b surface antigen (hbsag) was positive but deoxyribonucleic acid (hbv dna) by polymerase chain re ... | 2016 | 28043314 |
| a case of hepatocellular carcinoma presenting as a gingival mass. | oral metastatic tumor, which is uncommon and represents less than 1% of malignant oral neoplasms, usually arises from a primary mucosal or cutaneous cancer located in the head and neck regions. metastasis of hepatocellular carcinoma (hcc) to the oral cavity, especially to gingiva, is extremely rare. a 50-year-old man, who was a chronic alcoholic and hepatitis b virus carrier, presented with abdominal distension and weight loss for the past 3 months. three-phased contrast-enhanced abdominal ct re ... | 2016 | 28025476 |
| a case of chronic inflammatory demyelinating polyradiculoneuropathy after treatment with pegylated interferon α-2a in a patient with chronic hepatitis b virus infection. | we report the case of a 42-year-old man with chronic hepatitis b virus infection who developed weakness and paresthesia in the extremities 2 months after administration of pegylated interferon (peg-ifn)α-2a. nerve conduction studies conducted 6 months after onset showed abnormal temporal dispersions in both tibial nerves. we diagnosed chronic inflammatory demyelinating polyradiculoneuropathy (cidp) resulting from treatment with peg-ifnα-2a. neurological symptoms were prolonged despite suspension ... | 2016 | 27680223 |
| possible involvement of pcsk9 overproduction in hyperlipoproteinemia associated with hepatocellular carcinoma: a case report. | herein, we describe a 69-year-old japanese man with massive type iii hyperlipoproteinemia (total cholesterol, 855 mg/dl; triglyceride, 753 mg/dl) presenting as a paraneoplastic manifestation of hepatitis b virus-associated hepatocellular carcinoma. the messenger rna expression of sterol regulatory element-binding protein-2 and proprotein convertase subtilisin/kexin 9 in the tumor tissue was increased by 13-fold and 4-fold, respectively, compared with the non-tumor tissue. serum level of active f ... | 2016 | 27578139 |
| double primary hepatic cancer (hepatocellular carcinoma and intrahepatic cholangiocarcinoma) originating from hepatic progenitor cell: a case report and review of the literature. | synchronous development of primary hepatocellular carcinoma (hcc) and intrahepatic cholangiocarcinoma (icc) in different sites of the liver have rarely been reported before. the purpose of this study is to investigate the clinicopathological characteristics of synchronous double cancer of hcc and icc. | 2016 | 27535234 |
| enhanced pregenomic rna levels and lowered precore mrna transcription efficiency in a genotype a hepatitis b virus genome with c1766t and t1768a mutations obtained from a fulminant hepatitis patient. | the viral factors associated with the development of fulminant hepatitis b are not fully understood. we recently found four unique mutations [g to a at nucleotide 1742 (g1742a), c1766t, t1768a and t1809c] in the basal core promoter (bcp) region of a genotype a hepatitis b virus (hbv) strain (fh) obtained from a 53-year-old man with fatal fulminant hepatitis. to elucidate the association of the mutations of the fh genome with the disease, we constructed a 1.3-fold fh genome and its five variants ... | 2016 | 27473751 |
| a case of recurrent hepatocellular carcinoma acquiring complete remission of target lesion with treatment with traditional chinese medicine. | hepatocellular carcinoma (hcc) is one of the most prevalent malignancies worldwide. although surgery is known as the most promising radical treatment, a high recurrent or metastatic rate after surgery has limited its clinical efficacy. sorafenib, a target agent, has seemed to be the only option for metastatic hcc patients to date, but none of clinical trials showed it could prolong the overall survival (os) of advanced hcc to 1 year. how to prolong the os and improve cure rate of hcc patients is ... | 2016 | 27444311 |
| sequential therapy with peg-ifn alpha-2a and tenofovir in a hepatitis b virus-infected african man. | 2015 | 26897988 | |
| osteomalacia and fanconi's syndrome caused by long-term low-dose adefovir dipivoxil. | adefovir dipivoxil (adv) is recommended for patients infected with lamivudine-refractory hepatitis b virus (hbv). we report a case of low-dose adv-induced hypophosphatemic osteomalacia that initially presented as diffuse musculoskeletal pain. | 2015 | 25721615 |
| successful treatment of occult hepatitis b virus infection related membranous nephropathy after entecavir therapy. | we have reported a case of occult hepatitis b virus infection (obi) associated membranous nephropathy (mn) with complete remission under an ongoing 3.5-year entecavir monotherapy. a 59-year-old man with a 3-year history of liver cirrhosis was introduced to our department because of oliguria, proteinuria and microscopic haematuria. he, with negative serum hbv surface antigen, was not detected hbv dna in his serum. renal biopsy was performed and was compatible with a diagnosis of hepatitis b virus ... | 2015 | 25510219 |
| horizontal transmission of de novo hepatitis b between spouses: a case report. | we report a female patient with acute hepatitis b due to horizontal transmission of hepatitis b virus from her husband, who suffered from de novo hepatitis b. a 48-year-old man underwent peripheral blood stem cell transplantation (pbsct) for adult t-cell leukemia/lymphoma. nine months after the initial treatment, he was referred to our hospital because of jaundice. laboratory data showed elevated serum aminotransferase levels and hepatitis b surface antigen (hbsag) positivity. we diagnosed de no ... | 2015 | 25211282 |
| radiation-induced hepatitis b virus reactivation in hepatocellular carcinoma: a case report. | hepatitis b virus (hbv) reactivation associated with radiotherapy is rare. the present study reports the case of a 46-year-old man that experienced fatal hbv reactivation. the patient suffered from hepatocellular carcinoma (hcc) with portal vein tumor thrombus, which was treated by radiotherapy at a daily fraction of 2 gy over 5 weeks, up to a total radiation dose of ~50 gy. the patient presented with fatigue, yellow sclera and abdominal distension ~8 weeks subsequent to the administration of ra ... | 2015 | 26722314 |
| ectopic jejunal variceal rupture in a liver transplant recipient successfully treated with percutaneous transhepatic coil embolization: a case report. | here we present the rupture of ectopic jejunal varices developing in a liver transplant recipient without portal hypertension, which was successfully treated with percutaneous transhepatic coil embolization.a 48-year-old man with massive melena was admitted to our department. he had undergone liver transplantation for hepatitis b virus-related liver cirrhosis 8 months before, and his postoperative course was satisfactory except for an acute cellular rejection. no evidence of bleeding was detecte ... | 2015 | 26632745 |
| chronic hepatitis b infection presenting with chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (clippers): a case report. | chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids is a brainstem disorder characterized by perivascular pathologic reaction with lymphocyte infiltration and leading to diplopia, facial palsy, dysarthria, and gait ataxia. it was thought to be an autoimmune disorder without distinct pathogenesis. chronic hepatitis b virus infection has been proposed in correlation with autoimmune diseases, including central nervous system demyelinating disease. patients ... | 2015 | 26582039 |
| isolation of vaccinia jx594 from pustules following therapy for hepatocellular carcinoma. | jx594 is an oncolytic poxvirus derived from wyeth strain vaccinia virus. we reported the presentation of cutaneous and mucosal pustules containing laboratory-confirmed jx594 in a patient following injection of jx594. | 2015 | 26471278 |
| human herpes virus 8-unrelated primary effusion lymphoma-like lymphoma in the pericardium: a case with latency type iii epstein-barr virus infection showing good prognosis without chemotherapy. | primary effusion lymphoma (pel) is a rare subtype of non-hodgkin lymphoma that proliferates in body cavities without detectable masses. pel is universally associated with human herpes virus-8 (hhv-8) infection and has an aggressive prognosis. recently, an hhv-8-unrelated pel-like lymphoma that usually occurs in elderly individuals and follows a more indolent prognosis has been reported, and it is treated as a disease distinct from pel. however, its pathogenesis and prognostic factors have not be ... | 2015 | 26384578 |
| blocking the expression of the hepatitis b virus s gene in hepatocellular carcinoma cell lines with an anti-gene locked nucleic acid in vitro. | the aim of this study was to investigate the effects of inhibition of the hepatitis b virus (hbv) s gene by polypurine region locked nucleic acid on viral replication in cells. we designed and synthesized a locked nucleic acid, phosphorothioate oligonucleotides, unmodified oligonucleotides, and unrelated control sequence for the hepatitis b virus s gene polypurine region. hepg2.2.15 cells were transfected by cationic liposome, and fluorescence quantitative polymerase chain reaction technology (p ... | 2015 | 26125740 |
| reactivation of chronic hepatitis b during treatment with tenofovir disoproxil fumarate: drug interactions or low adherence? | we describe a case of a 61-year-old man with chronic hepatitis b, hepatitis b e antibody (hbeab) positive, treated with tenofovir disoproxil fumarate (tdf), who developed virological and biochemical viremic reactivation with an increase in transaminase plasma levels. the patient's history revealed that he had discontinued tdf about 5 days before admission and, from december 2013, had been taking venlafaxine, paroxetine and zolpidem for some episodes of depression. clinical evaluation and laborat ... | 2015 | 26123461 |
| primary lymphoepithelioma-like hepatocellular carcinoma: report of a locally advanced case and review of literature. | lymphoepithelioma-like hepatocellular carcinoma is rare, which has been recognized as a variant of hepatocellular carcinoma. here we report a locally advanced case of lymphoepithelioma-like hepatocellular carcinoma. a 50-year-old man with chronic hepatitis b virus infection presented with a single mass in the liver and two enlarged lymph nodes in retroperitoneum suspected to be hepatocellular carcinoma with lymph node metastasis. after discussion by multidisciplinary team, the patient underwent ... | 2015 | 26045853 |
| reactivation of hepatitis b (reverse seroconversion) after melphalan/dexamethasone therapy for primary amyloidosis: a case report. | hepatitis b virus (hbv) reactivation (so-called reverse seroconversion) is a rare but known complication of hematopoietic stem cell transplantation, immunosuppressive therapy, or high-dose chemotherapy plus rituximab. this event is linked to a treatment-related fall in titers of antibodies to hepatitis b surface antigen (hbsab) below the protective threshold level. | 2015 | 26031455 |
| remission of splenic marginal zone lymphoma in a patient treated for hepatitis b: a case of hbv-associated lymphoma. | splenomegaly is a common finding in chronic hepatitis b infection. we present the case of a man with an acute flare of chronic hepatitis b infection, where splenomegaly in absence of portal hypertension led to the diagnosis of splenic marginal zone lymphoma (smzl) with bone marrow involvement. adequate suppression of the hepatitis b virus (hbv) viral load with tenofovir resulted in complete remission of the lymphoma. | 2015 | 25977147 |
| hepatocellular carcinoma with concomitant hepatic angiomyolipoma and cavernous hemangioma in one patient. | the risk of developing hepatocellular carcinoma (hcc) is strongly associated with hepatitis b virus infection. hepatic angiomyolipoma (aml), a rare benign tumor, is composed of a heterogeneous mixture of adipose cells, smooth muscle cells and blood vessels. here, we report the case of a 44-year-old man who developed hcc with a concomitant hepatic aml and a cavernous hemangioma, in the absence of cirrhosis. to our knowledge, based on an extensive literature search using the www.pubmed.gov website ... | 2015 | 25805953 |
| salvage living-donor liver transplantation for liver failure following definitive radiation therapy for recurrent hepatocellular carcinoma: a case report. | a 57-year-old man with a history of hepatitis b virus infection was referred to our hospital for living-donor liver transplantation (ldlt). five years earlier, right lobectomy had been performed for solitary hepatocellular carcinoma (hcc) with bile duct tumor thrombus in segments 5 and 6 in the liver. two years later, transarterial chemoembolization and radiofrequency ablation were performed for recurrent hcc. two years after those local therapies, another recurrent hcc was treated with transhep ... | 2015 | 25891735 |
| successful living-donor liver transplant for fulminant hepatitis in a heart recipient. | reactivation of hepatitis b virus replication is a known complication of immunosuppressive therapy, which can lead to hepatocellular injury, liver failure, and death. in this report, we describe the case of a 44-year-old man with chronic hepatitis b and a dilated cardiomyopathy status after a heart transplant. reactivation of the patient 's hepatitis b virus occurred 4 months after the heart transplant. despite prompt administration of antiviral therapy, he developed fulminant hepatitis with hep ... | 2015 | 24650356 |
| a case of cerebral tuberculosis after liver transplant and literature review. | the risk of active tuberculosis is high in solid-organ recipients. we evaluated the clinical presentation of tuberculosis. pulmonary locations were the most frequent, and extrapulmonary locations were rarely seen. among extrapulmonary sites, intracranial tuberculosis is rare, with a few case reports reported in the literature. we report a case of 27-year-old man, who received deceased-donor liver transplant due to hepatitis b virus-related chronic liver failure. one month after the liver transpl ... | 2014 | 24635807 |
| a unique bleeding-related complication of sorafenib, a tyrosine kinase inhibitor, in advanced hepatocellular carcinoma: a case report. | sorafenib, a multikinase inhibitor as a standard of care for advanced hepatocellular carcinoma, may lead endothelial cells to an unstable state by blocking the signaling pathway of vascular endothelial growth factor receptor, which may result in the disruption of the architecture and integrity of the microvasculature, and eventually increase the risk of hemorrhage. hemobilia is a relatively uncommon condition as a consequence of hepatocellular carcinoma and its risk factors remain uncertain. | 2014 | 24571585 |
| schistosomiasis japonicum diagnosed on liver biopsy in a patient with hepatitis b co-infection: a case report. | chronic hepatitis b virus and schistosomiasis are independently associated with significant mortality and morbidity worldwide. despite much geographic overlap between these conditions and no reason why co-infection should not exist, we present what is, to the best of our knowledge, the first published report of a proven histological diagnosis of hepatic schistosomiasis japonicum and chronic hepatitis b co-infection. a single case of hepatitis b and hepatic schistosomiasis mansoni diagnosed by li ... | 2014 | 24521427 |
| hypophosphatemic osteomalacia due to drug-induced fanconi's syndrome associated with adefovir dipivoxil treatment for hepatitis b. | we herein present the case of a 58-year-old japanese man with fanconi's syndrome with a 13-month history of bone pain in his ribs, hips, knees and ankles. he had been receiving low-dose adefovir dipivoxil (adv) for the treatment of lamivudine-resistant chronic hepatitis b virus infection for eight years and subsequently developed severe hypophosphatemia and proximal renal tubule dysfunction. magnetic resonance imaging showed multiple insufficiency fractures in the ribs, ileum, tibia and calcaneu ... | 2014 | 24492692 |
| eruptive purpuric papules on the arms; a case of chemotherapy-induced inflammation of actinic keratoses and review of the literature. | chemotherapy-induced inflammation of actinic keratosis can present in patients with subclinical actinic keratoses that become erythematous and pruritic within weeks of initiating systemic chemotherapy. the reaction is limited to sun-exposed areas and, classically, histologic findings of parakeratosis and epidermal necrosis with keratinocyte nuclear pleomorphism are present. exuberant reactions with extensive epidermal necrosis may lead to subepidermal vesiculation. we report a case of a 67-year- ... | 2014 | 24456949 |
| entecavir-associated myopathy: a case report and literature review. | entecavir, a nucleoside analog (na), is effective for treatment of chronic hepatitis b virus (hbv) infection. | 2014 | 24218312 |
| novel hepatitis b virus strain developing due to recombination between genotypes h and b strains isolated from a japanese patient. | in japan, genotypes b and c are the predominant genotypes isolated from patients with chronic hepatitis b, while genotype a predominates in patients with acute hepatitis b. globalization, however, appears to have changed the distribution of the hepatitis b virus (hbv) genotypes. thus, the viral characteristics of hbv genotypes other than genotypes a, b and c were examined. | 2014 | 24020990 |
| fibrosing cholestatic hepatitis after successful interferon and ribavirin therapy for recurrent hepatitis c post living related liver transplantation: a case report. | a 33-year-old japanese man who had suffered from liver cirrhosis due to hepatitis c virus (hcv) underwent living related liver transplantation (lrlt). the allograft was given by his brother, who was healthy with no history of hepatitis or hepatic virus infection. after lrlt, the patient's hepatitis c recurred. liver biopsy revealed chronic viral hepatitis and no allograft rejection such as shown by portal lymphocytic infiltration or mild bridging fibrosis. interferon and ribavirin were administe ... | 2014 | 25803885 |
| [a case of hcc with portal vein thrombosis treated with multidisciplinary treatment combined with preoperative sbrt and radical resection]. | a 70s man with advanced hepatocellular carcinoma (hcc) with portal vein tumor thrombosis (pvtt) (vp-hcc) in the main trunk (vp4) was referred to our hospital. he was negative for hepatitis c virus (hcv) and hepatitis b virus (hbv), and his liver function was well preserved. the main tumor was in the right lobe and exceeded 10 cm in diameter. there were no intrahepatic metastases to the left lobe. the patient underwent stereotactic body radiation therapy (sbrt) (48 gy/4 fractions) to the area of ... | 2014 | 25731445 |
| a case of entecavir resistance which is developed after complete viral suppression during entecavir treatment for nucleoside-naive chronic hepatitis b. | entecavir (etv) is a potent nucleoside analogue against hepatitis b virus (hbv), and the emergence of drug resistance is rare in nucleoside-naive patients because development of etv resistance (etvr) requires at least three amino acid substitutions in hbv reverse transcriptase. we observed a case of genotypic etvr with viral and biochemical breakthrough during etv treatment of nucleoside-naive patients with chronic hepatitis b (chb). a 57-years-old hbeag-positive man received etv 0.5 mg/day for ... | 2014 | 25910308 |
| efficacy and safety of tenofovir in a kidney transplant patient with chronic hepatitis b and nucleos(t)ide multidrug resistance: a case report. | five nucleos(t)ide analogs are used to treat chronic hepatitis b. ideal nucleos(t)ide analog therapy in chronic hepatitis b patients with kidney transplantation must ensure virological suppression and minimize renal injury. however, resistance to nucleos(t)ide analogs frequently results in virological breakthrough, hepatitis flare, and complicated deterioration of the transplanted kidney. inappropriate rescue therapy for drug resistance may subsequently cause hepatitis b virus multidrug resistan ... | 2014 | 25146249 |
| bilateral simultaneous nonarteritic anterior ischemic optic neuropathy in a patient with alcoholic liver disease. | a 53-year-old man with a history of alcoholism since 10 years admitted for jaundice elsewhere developed bilateral simultaneous decrease in vision in both the eyes 4 days after admission. his best-corrected visual acuity was 20/20 in both eyes. visual field evaluation revealed an inferior altitudinal defect in both the eyes. optic disc appearance, visual fields, and optical coherence tomography of discs were suggestive of nonarteritic anterior ischemic optic neuropathy (naion) in both the eyes. l ... | 2014 | 25136231 |
| successful treatment with entecavir for reactivation of hepatitis b virus following systemic chemotherapy in a hepatitis b surface antigen-negative patient with colorectal cancer. | reactivation of hepatitis b virus (hbv) has recently been reported as a fatal complication in patients undergoing cytotoxic chemotherapy. we herein describe a case of reactivation in a 76-year-old man who had undergone pelvic exenteration for colorectal cancer (crc). he was treated with a modified folfox6 chemotherapy regimen after the operation. thirteen months later, his laboratory data showed severe liver dysfunction. his hepatitis b surface antigen (hbsag) test was positive, and his hbv-dna ... | 2014 | 25130106 |
| prevalence of and factors influencing impaired glucose tolerance among hepatitis b carriers: a nationwide cross-sectional study in the republic of korea. | diabetes is associated with a poor prognosis for liver disease, particularly in chronic hepatitis carriers. we investigated the prevalence of factors associated with impaired glucose tolerance (igt) including diabetes and impaired fasting glucose (ifg) among individuals with hepatitis b virus (hbv) infection.we used data from the korean national health and nutrition examination survey, a nationwide cross-sectional survey conducted between 2007 and 2011. sociodemographic information was collected ... | 2014 | 25365406 |
| double primary hepatic cancer (sarcomatoid carcinoma and hepatocellular carcinoma): a case report. | primary liver sarcomatoid carcinoma (sc) is a rare and aggressive tumor exhibiting rapid growth and a high recurrence rate following resection. to date, there have been no reports of primary liver sc occurring simultaneously with hepatocellular carcinoma (hcc). this is the case report of a 54-year-old man with liver cirrhosis due to hepatitis b virus (hbv) infection and alcoholic hepatitis. the abdominal computed tomography and magnetic resonance imaging revealed two distinct hepatic masses in a ... | 2014 | 25279179 |
| glioblastoma multiforme and hepatitis b: do the right thing(s). | hepatitis b virus (hbv) reactivation is a well-known complication related to immunosuppression. clinical manifestations of hbv relapse range from self-limiting anicteric hepatitis to acute hepatic failure. temozolomide (tmz) is an alkylating agent used for the treatment of glioblastoma multiforme (gbm), the most common and deadliest of malignant primary brain tumors. | 2014 | 25535132 |
| recall radiation dermatitis by sorafenib following stereotactic body radiation therapy. | we report on a 63-year-old man with a history of hepatitis b virus-related hepatocellular carcinoma with a thrombus extending into the inferior vena cava, who received image-guided stereotactic body radiation therapy (sbrt) with helical tomotherapy, followed by sorafenib. a total tumor dose of 48 gy was delivered by 6 fractions within 2 weeks. the tumor responded dramatically, and the patient tolerated the courses well. ten days after sbrt, sorafenib (200 mg), at 1.5 tablets twice a day, was pre ... | 2014 | 24971021 |
| an hbv-hiv co-infected patient treated with tenofovir-based therapy who achieved hbs antigen/antibody seroconversion. | the present report describes a case of a patient with hepatitis b virus (hbv)-human immunodeficiency virus (hiv) co-infection who was treated with tenofovir disoproxil (tdf)-based highly active antiretroviral therapy (haart) and who achieved hbs antigen (ag)/antibody (ab) seroconversion. an 18-year-old japanese man with hiv and hbv co-infection presented to our hospital. his cd4 count was decreased, and tdf-based harrt was started. at 30 months after initiation of therapy, hbsag was not detected ... | 2014 | 24930654 |
| can pegylated interferon α 2a cause development of thyroid disorders in patients with chronic hepatitis b? | hepatitis b virus infection is treated with pegylated (peg) ifnα and nucleos(t)ide analogues. the disadvantages of pegifnα include thyroid disorders. in this single-center study, the type, incidence and consequences of thyroid dysfunction in patients receiving pegifnα due to chronic hepatitis b (chb) were analyzed. | 2014 | 24930451 |
| coexistence of hbsag and hbsab in a difficult-to-treat chronic hepatitis b: loss of hbsag with entecavir plus tenofovir combination. | some reports have documented the coexistence of hepatitis b surfage antigen (hbsag) and anti-hbsag antibodies (hbsab) in patients with chronic hepatitis b (chb), often in the absence of amino acid substitutions in the hbsag sequences of the hepatitis b virus (hbv) genome able to explain an immunological escape variant.hbv genome has a very compact coding organization, with four partially overlapping open reading frames (orfs). because the reverse transcriptase region (rt) of hbv polymerase overl ... | 2014 | 24885182 |
| hepatitis b virus-associated nephropathy in a patient with diabetes mellitus. | hepatitis b virus (hbv)-associated nephropathy is not a rare manifestation of hbv infection; this could result in diagnostic confusion and the possible misidentification of a diabetic patient with albuminuria. we present the first published case of a hbv-associated nephropathy occurring in a patient with diabetes. the patient was a 24-year-old man who was admitted to hospital with 4 days of generalized swelling and oliguria. he had a 3-year history of weight loss, and a 1-year history of polydip ... | 2014 | 24843742 |
| telbivudine during the second and third trimester of pregnancy interrupts hbv intrauterine transmission: a systematic review and meta-analysis. | beckground: evaluate the efficacy and safety of telbivudine during the 2nd and 3rd trimester of pregnancy in intrauterine transmission of hepatitis b virus (hbv). based on the principle of cochrane systematic reviews, a database was constructed from medline, embase, cochrane library, the us national science digital library (nsdl), the china biological medicine database (cbm-disc), and contact with chinese experts in the field from november 2006 to february 2013. | 2014 | 24779291 |
| screening of hepatocyte proteins binding with the middle surface protein of the hepatitis b virus by the yeast two-hybrid system. | the effect of the middle hepatitis b virus surface protein (mhbs) remains to be elucidated. to investigate the biological function of the mhbs protein, the present study performed yeast two-hybrid screening to search for proteins that interact with the mhbs protein in hepatocytes. the bait plasmid expressing the mhbs protein was constructed by cloning the gene of the mhbs protein into pgbkt7, then the recombinant plasmid dna was transformed into ah109 yeast (a type). the transformed yeast ah109 ... | 2014 | 24676405 |
| right upper-quadrant pain in a patient with drug abuse, secondary syphilis and occult hepatitis b virus. | to describe the etiology of hepatitis and identify occult hepatitis b virus (hbv) infection. | 2014 | 24662615 |
| community-acquired necrotizing fasciitis caused by acinetobacter calcoaceticus: a case report and literature review. | a 61-year-old man presented with pain in the abdomen and right lower limb. he had a history of hepatitis b virus-induced liver cirrhosis, but had not been visiting the outpatient clinic and did not receive any medication. cutaneous necrosis and bulla were observed on his abdomen and right lower limb. the necrotic skin was incised, and he was diagnosed with necrotizing fasciitis. a nonfermentative gram-negative bacillus infection was confirmed from aspirated fluid and blood cultures. therefore, m ... | 2014 | 24507651 |
| parsonage-turner syndrome following post-exposure prophylaxis. | the 'parsonage-turner syndrome' (pts) is a rare but distinct disorder with an abrupt onset of shoulder pain, followed by weakness and atrophy of the upper extremity musculature, and a slow recovery requiring months to years. to our best knowledge, this is the first case describing symptoms and signs of pts following the administration of a post-exposure prophylaxis (pep) regimen against possible human immunodeficiency virus (hiv) and hepatitis b virus (hbv) infection. | 2014 | 25098693 |
| acute hepatitis b of genotype h resulting in persistent infection. | a 47-year-old man presented with general fatigue and dark urine. the laboratory data showed increased levels of hepatic transaminases. the patient was positive for hepatitis b virus (hbv) markers and negative for anti-human immunodeficiency virus. the hbv-dna titer was set to 7.7 log copies/ml. the patient was diagnosed with acute hepatitis b. the hbv infection route was obscure. the serum levels of hepatic transaminases decreased to normal ranges without any treatment, but the hbv-dna status wa ... | 2014 | 24659896 |
| [adult gianotti-crosti syndrome caused by hepatitis b]. | a 42-year-old man was admitted to our hospital with a lower extremity rash, general fatigue, and abdominal discomfort. laboratory findings revealed elevated serum transaminases as well as positivity for the hepatitis b surface antigen and the immunoglobulin m type anti-hepatitis b core antibody. he was diagnosed with a rash typical of gianotti-crosti syndrome due to acute infection with hepatitis b virus, genotype a. after admission, the rash gradually decreased; however, serum transaminases and ... | 2013 | 24005107 |
| hbv reactivation in an occult hbv infection patient treated with prednisone for nephrotic syndrome: case report and literature review. | reactivation of hepatitis b virus (hbv), characterized by increased levels of serum hbv dna, abnormal liver function and hepatic failure, is a frequent complication of immunosuppressive therapy and chemotherapy in patients with hbv infection. however, reactivation of occult hbv infection with immunosuppressive therapy or chemotherapy is rare. | 2013 | 23977980 |
| inferior vena cava tumor thrombus that directly infiltrated from paracaval lymph node metastases in a patient with recurrent hepatocellular carcinoma. | herein, we present the case of a patient with recurrent hepatocellular carcinoma (hcc) who had paracaval lymph node (ln) metastases with an inferior vena cava (ivc) tumor thrombus after a hepatectomy. a 65-year-old man with chronic hepatitis b virus infection received an extended anterior segmentectomy because of two hepatic tumors, located in segments 7 and 8. histological examination of both resected specimens showed mostly moderately differentiated hcc with some poorly differentiated areas, a ... | 2013 | 23915104 |
| [complete response after sorafenib therapy plus zoledronic acid for advanced hepatocellular carcinoma with bone metastasis - a case report]. | sorafenib is an oral multi-kinase inhibitor that targets tumor growth and angiogenesis signal transduction pathways. two global phase iii trials showed that sorafenib prolonged the survival of patients with advanced hepatocellular carcinoma (hcc). based on the positive results of these trials, japan approved sorafenib for advanced hcc in may 2009. however, in the sharp trial and the asia-pacific trials, no cases of complete response(cr)were reported. thereafter, only a relatively small number of ... | 2013 | 23863589 |
| hbsag loss is not an ideal indicator for discontinuing treatment of hbeag-negative chronic hepatitis b: a case report. | we experienced a case of a 36-year-old married man who was found to be hepatitis b virus (hbv) positive at 23 years of age. his liver function was repeatedly abnormal in the past 13 years. in november 2007 he presented with fatigue. laboratory tests showed serum alanine aminotransferase concentration 255.3 u/l, positive for hepatitis b surface antigen (hbsag) and hepatitis b e antibody, hbv dna 3.01 × 10(7) copies/ml; liver biopsy showed necroinflammatory scores 11 and fibrosis scores 4. after 2 ... | 2013 | 23783395 |
| successful resection of intracranial metastasis of hepatocellular carcinoma. | intracranial metastasis of hepatocellular carcinoma (hcc) is rare, but has an extremely poor prognosis. we report a case with successful surgical removal of intracranial metastasis of hcc. a 32-year-old man was admitted to our hospital with severe vomiting. he had been followed for liver cirrhosis due to hepatitis b virus infection and received a right hepatic trisectionectomy for hcc 1 year earlier. for the recurrence of hcc, sorafenib had been administered 6 months before admission. on admissi ... | 2013 | 23626520 |
| transverse sinus thrombosis in a living donor: a case report. | liver transplantation is among the treatment options for end-stage liver disease. limited organ donation in our country has resulted in an increased performance of living donor liver transplantations. this case report describes a left transverse cerebral venous sinus thrombosis diagnosed in a living donor hepatectomy patient. | 2013 | 23622615 |
| progressive liver failure induced by everolimus for renal cell carcinoma in a 58-year-old male hepatitis b virus carrier. | a 58-year-old man was diagnosed as a hepatitis b virus (hbv) carrier approximately 30 years ago. he was diagnosed with renal cell carcinoma when he was 57 years old. radical nephrectomy was performed, and everolimus was administered to treat his lung metastasis. after beginning the everolimus, intermittent fever, general fatigue, and jaundice developed. he was admitted under a diagnosis of flare (acute exacerbation) of chronic b hepatitis due to hbv reactivation. despite intensive care, he died ... | 2013 | 23606919 |
| [impact of hepatitis b virus on sperm parameters and outcome of assisted reproductive technology]. | with the development of assisted reproductive technology (art), more and more hepatitis b virus (hbv)-infected couples have their own children successfully; however,vertical transmission of hbv in art, especially father-to-child transmission, cannot be avoided. the mechanism of attachment and penetration of hbv into human sperm is still not known. therefore, understanding the state and mechanism of hbv infection of sperm and the impact of hbv on sperm parameters, following up the art outcome in ... | 2013 | 23585013 |
| combined hepatocellular-cholangiocarcinoma with stem cell features, ductal plate malformation subtype: a case report and proposal of a new subtype. | in the current who blue book, combined hepatocellular-cholangiocarcinoma (c-hcc-cc) was classified into two types; classical type and type with stem cell features. the latter is extremely rare, and is subcategorized into the following three subtypes; typical subtype, intermediate cell subtype, and cholangiocellular subtype. recently, intrahepatic cholangiocarcinoma (icc) with features of ductal plate malformations (dpm) have been reported, and the icc with dpm was proposed as a subtype of icc. t ... | 2013 | 23573322 |
| adefovir is effective to promote development of immunity to donor origin hepatitis b virus in an allogeneic transplant recipient: a case report. | hepatitis b infection is a serious health problem in endemic areas particularly among immunocompromised patients. the more profound immunosuppression in recipients of hematopoietic stem cell transplantations (hct) can lead to more complicated hepatitis b virus (hbv)-related events. despite the high risk of recipient infection allogeneic hct donors with hbv infection are not excluded in the absence of an alternative donor. a 25 year-old man with severe aplastic anemia underwent allogeneic hct fro ... | 2013 | 23498831 |
| molecular epidemiology of hepatitis b in the indigenous people of northern australia. | the hepatitis b surface antigen was first described in the blood of an indigenous australian man, yet little is known about its molecular epidemiology in this population, in which it is endemic. the study aimed to determine the clinical and molecular epidemiology of hepatitis b virus (hbv) in indigenous people from northern australia. | 2013 | 23432545 |
| hepatitis b and e co-primary infections in an hiv-1-infected patient. | we report an autochthonous hepatitis e virus (hev)-hepatitis b virus co-primary infection in a 41-year-old man having sex with men and infected with human immunodeficiency virus (hiv). this case prompts testing for hev in hiv-infected patients with acute hepatitis even if primary infection with another hepatitis virus is diagnosed. | 2013 | 23303497 |
| hepatitis b virus reactivation induced by infliximab administration in a patient with crohn's disease. | a 47-year-old man diagnosed with crohn's disease was treated with infliximab. he tested negative for hepatitis b surface antigen (hbsag) and hepatitis b surface antibody (anti-hbs) but positive for anti-hb core antibody (anti-hbc). he tested positive for hepatitis b virus (hbv-) dna 3 months after treatment and was administered entecavir. hbv-dna test showed negative results 1 month later. alt was persistently within the normal range, and hbv-dna was persistently negative thereafter despite the ... | 2013 | 25374717 |
| treatment options for hepatitis delta virus infection. | the hepatitis d virus (hdv), the smallest virus known to infect man, causes the most severe form of chronic viral hepatitis, hepatitis delta. it is estimated that about 15 to 20 million people are suffering from chronic hdv infection. hdv is a defective satellite virus depending on the hepatitis b surface antigen (hbsag) for transmission. chronic hepatitis delta is associated with a rapid progression of liver fibrosis and a high prevalence of liver cirrhosis, even in younger patients. immunizati ... | 2013 | 23242761 |
| successful kidney transplantation from a hepatitis b surface antigen-positive donor to an antigen-negative recipient using a novel vaccination regimen. | transplanting a kidney from a hepatitis b surface antigen (hbsag)-positive donor to an hbsag-negative recipient who is naturally immune has been successful in countries endemic for hepatitis b virus (hbv). however, in most of these cases, the donors were deceased. we present a report of a successful hbsag-discordant kidney transplantation in the united states; in this case, a living donor kidney was transplanted to a vaccinated recipient. the wife of a 58-year-old hbsag-negative man volunteered ... | 2013 | 23219109 |
| hepatitis b virus dna integration in tumour tissue of a non-cirrhotic hfe-haemochromatosis patient with hepatocellular carcinoma. | co-existence of multiple causes of liver injury increases the risk of hepatocellular carcinoma (hcc) development. hcc usually develops in patients with cirrhosis although it may also occur in individuals with no or mild liver disease, in particular in cases with hepatitis b virus (hbv) infection. here we report the case of a 43year-old man with hfe-haemochromatosis, seronegative for hepatitis b and c infections, who developed hcc in the absence of severe liver damage. both tumoural and non-tumou ... | 2013 | 22989571 |
| lactic acidosis during telbivudine treatment for hbv: a case report and literature review. | all oral nucleoside analogues against hepatitis b virus, with an exception of telbivudine, have been reported causing lactic acidosis (la). here we report the first case of chronic hepatitis b developing severe refractory la during telbivudine monotherapy. a 36-year-old man of chinese origin received telbivudine antiviral treatment for chronic hepatitis b. after 11 mo of therapy, he developed anorexia, nausea, and vomiting with mild muscle weakness. the patient was found with elevated serum crea ... | 2013 | 24023503 |
| [a case of hepatocellular carcinoma with vp4 tumor thrombus treated by radiation therapy before hepatectomy]. | a 61-year-old man who complained of right hypochondralgia was diagnosed as hepatocellular carcinoma (hcc) associated with hepatitis b virus (hbv) infection. the tumor was located in the right lobe and s3, and the tumor thrombus extended into the main portal and left portal veins. preoperatively, real-time tumor-tracking radiation therapy was performed on the tumor thrombus (20 gy/4 fr),after vessel coils were placed at the anterior hepatic artery as a marker for the radiation. ten days after rad ... | 2013 | 24393929 |
| a pilot cohort study to assess the feasibility of hiv prevention science research among men who have sex with men in dakar, senegal. | men who have sex with men (msm) are disproportionately burdened by hiv in senegal, across sub-saharan africa and throughout the world. this is driven in part by stigma, and limits health achievements and social capital among these populations. to date, there is a limited understanding of the feasibility of prospective hiv prevention studies among msm in senegal, including hiv incidence and cohort retention rates. | 2013 | 24321115 |