Publications

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high hpv genetic diversity in women infected with hiv-1 in brazil.the present study on genetic diversity of human papillomaviruses in women infected by hiv in brazil describes the frequency, the genotypes, and five new variants of hpv. one hundred fifty cervical smears of hiv-positive women were subjected to cytological examination, and the dna samples obtained were assayed by my09/my11 amplification, followed by rflp typing. the overall hpv-dna-positive rate was 42.7%. one hundred twenty-two samples (81.3%) had benign cellular alterations or normal cytologica ...200716896550
complete genome and phylogenetic position of bovine papillomavirus type 7.six bovine papillomavirus (bpv) types and 16 putative bpv types have been reported previously. here, the complete genome sequence of bapv6, a novel putative bpv type isolated from cattle in japan, was determined by using multiple-primed rolling-circle amplification. the genome consisted of 7412 bp (g+c content of 46 mol%) that encoded five early (e1, e2, e4, e6 and e7) and two late (l1 and l2) genes, but did not encode the e5 gene. the e6 protein contained a non-consensus cxxc(x)(33)cxxc and a c ...200717554025
genetic diversity of cutaneous human papillomaviruses.human papillomaviruses (hpvs) of the genera betapapillomavirus and gammapapillomavirus are common on human skin. sequencing of subgenomic amplicons of cutaneous hpvs has revealed a large number of novel putative hpv types within these genera. phylogenetic analysis based on these amplicons revealed 133 putative hpv types with <90 % sequence identity to any known hpv type or to each other. as there are already 34 characterized hpv types described within the genera betapapillomavirus and gammapapil ...200717872517
[study on the genotyping of human papillomavirus using a new dna liquid chip in women of high-risk group of shandong province].to evaluate the diagnostic applicability of human papillomavirus (hpv) liquid chip assay which is based on luminex xmap system, and perform a hpv epidemiologic study with the liquid chip in women of shandong province.200717877181
oral medicine case book 2. 200718260551
circumcision and sexual behavior: factors independently associated with human papillomavirus detection among men in the him study.there is growing interest in understanding human papillomavirus (hpv) infection and related disease among men. to date there have been numerous studies reporting hpv dna prevalence among men from several different countries, however, few have incorporated multivariable analyses to determine factors independently associated with male hpv detection. the purpose of this study was to assess the factors independently associated with hpv detection in men ages 18-70 years residing in brazil (n = 343), ...200919089913
detection of alpha- and beta-human papillomavirus (hpv) in cutaneous melanoma: a matched and controlled study using specific multiplex pcr combined with dna microarray primer extension.there are few contradictory studies investigating the involvement of hpv in melanoma. we designed a controlled study to evaluate the hpv dna prevalence in melanoma. one hundred patients with cutaneous malignant melanoma diagnosed between 2002 and 2006 were included. complementary wide excision (healthy skin) was performed in 85 patients and was used as internal control. after dna extraction, 68 different hpv types were studied using a multiplex pcr combined with microarray primer extension. we d ...200919469900
identification of a novel human gammapapillomavirus species.by using random pcr amplification, shotgun sequencing and sequence similarity searches, we analysed nucleic acids present in cell cultures inoculated with samples from unexplained cases of encephalitis. we identified a divergent human papillomavirus (hpv) sequence originating from a rectal swab. the full genome was amplified by inverse pcr and sequenced. the prototype of the sixth gammapapillomavirus species, hpv116, was not found in the patient's cerebrospinal fluid or respiratory secretions, n ...200919570953
comparison of the novel human papillomavirus 4 auto-capillary electrophoresis test with the hybrid capture 2 assay and with the pcr hpv typing set test in the detection of high-risk hpv including hpv 16 and 18 genotypes in cervical specimens.the aim of this study was to compare the novel human papillomavirus (hpv) detection method, the hpv 4 auto-capillary electrophoresis (ace) test with the hybrid capture (hc) 2 assay for the detection of high-risk hpvs. in addition, we compared the hpv 4 ace test with the polymerase chain reaction hpv typing set test for the detection of hpv 16 and hpv 18 genotypes. one hundred ninety-nine cervical swab samples obtained from women with previous abnormal pap smears were subjected to testing with th ...200919654936
epidermodysplasia-verruciformis-like eruption associated with gamma-papillomavirus infection in a patient with adult t-cell leukemia.epidermodysplasia verruciformis (ev) is a genodermatosis characterized by widespread and persistent cutaneous lesions caused by beta-papillomaviruses. rare cases of acquired ev-like eruption associated with beta-papillomavirus infection have been reported in immunosuppressed patients. we report a case of acquired ev-like eruption in an immunosuppressed patient with adult t-cell leukemia. the cutaneous lesions clinically resembled pityriasis versicolor and exhibited the typical histological featu ...200919696474
pigmented wart due to human papilloma virus type 60 showing parallel ridge pattern in dermoscopy. 200919709979
correlates for completion of 3-dose regimen of hpv vaccine in female members of a managed care organization.to examine the rate and correlates of completion of the quadrivalent human papillomavirus vaccine (hpv4) 3-dose regimen because nonadherence to the regimen may adversely affect vaccine efficacy.200919797775
the case for hpv immunization.hpv4 is now available for boys, and a second vaccine to protect against hpv-associated cancer has been approved. should you be using these vaccines in your practice?200919961821
[rna interference: biogenesis molecular mechanisms and its applications in cervical cancer].rnai (rna interference) is a natural process by which eukaryotic cells silence gene expression through small interference rnas (sirna) which are complementary to messenger rna (mrna). in this process, the sirna that are 21-25 nucleotides long and are known as microrna (mirna), either associate with the rna-induced silencing complex (risc), which targets and cleaves the complementary mrnas by the endonucleolytic pathway, or repress the translation. it is also possible to silence exogenous gene ex ...201020415061
presence and persistence of human papillomavirus types 1, 2, and 4 on emery boards after scraping off plantar warts. 201020082896
correlates for human papillomavirus vaccination of adolescent girls and young women in a managed care organization.the authors studied the characteristics of those who initiated the human papillomavirus (hpv) vaccine versus those who did not. female members of kaiser permanente southern california aged 9-26 years were identified and assessed for hpv vaccination between october 2006 and march 2008. multivariable log-binomial regression was used to examine the association of the following factors with vaccine initiation: 1) demographics, 2) provider characteristics, 3) health care utilization, 4) women's healt ...201020047978
the oral cavity contains abundant known and novel human papillomaviruses from the betapapillomavirus and gammapapillomavirus genera.background.ôçâhuman papillomaviruses (hpvs) primarily sort into 3 genera: alphapapillomavirus (+¦-hpv), predominantly isolated from mucosa, and betapapillomavirus (+¦-hpv) and gammapapillomavirus (+¦-hpv), predominantly isolated from skin. hpv types might infect body sites that are different from those from which they were originally isolated. methods.ôçâwe investigated the spectrum of hpv type distribution in oral rinse samples from 2 populations: 52 human immunodeficiency virus (hiv)-positive ...201121844305
genomic characterization of ten novel cutaneous human papillomaviruses from keratotic lesions of immunosuppressed patients.viral warts from immunosuppressed organ transplant recipients (otr) persist over years and may progress into non-melanoma skin cancer. the types of human papillomaviruses (hpv) in such lesions are different from that seen in the general population. a subset of these lesions is not infected with the classical wart-associated hpv types. in order to get a better understanding of the hpv types in those lesions, we isolated ten novel hpv from atypical persisting keratotic lesions of immunosuppressed ...201121471318
human papillomavirus vaccine: now for boys too? 201121157346
Molecular cloning and characterization of a novel human papillomavirus, HPV 126, isolated from a flat wart-like lesion with intracytoplasmic inclusion bodies and a peculiar distribution of Ki-67 and p53.Infection with certain human papillomavirus types induces warts with specific macroscopic and microscopic features. We observed multiple flat wart-like lesions on the chest, neck and extremities of an adult T-cell leukemia patient. Histologically, atypical intracytoplasmic inclusion bodies currently known to be pathognomonic for genus gamma or mu papillomaviruses were disclosed in some cells of the epidermis showing histological features compatible with flat warts. In the present study, a novel ...201222056388
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