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studies upon the etiology of dengue fever : i. experimental transmission to the lower animal.the dengue cases studied during this epidemic were, as a whole, typical examples of the disease. the onset was sudden, often of a violent character, ushered in with severe headache and backache, vague pains throughout the body, and fever ranging from 101-105 degrees f. on the 2nd or 3rd day a maculopapular eruption appeared, generally on the neck, chest, and arms, but sometimes more widely disseminated. in most instances the fever remained for 3 or 4 days, after which it dropped to normal to ris ...192419868961
neurochemistry of the spinal cord in british saddleback piglets affected with congenital tremor, type a-iv, a second form of hereditary cerebrospinal hypomyelinogenesis. 19734737478
[ glucose concentration in blood during exertion. 5. use of the total distribution of blood glucose values during physical exercise or the estimation of response to exertion in various breeds of swine].blood glucose was determined by an enzymic method in 56 pigs of the german edelschwein, german landrace, german saddleback breeds and edelschwein/landrace crosses before, during and after exercise on a belt moving at 1.3 metres/second for ten minutes, at 10 degrees c (winter) or 22-34 degrees c (summer) and relative humidity of 65-75%. total plasma glucose was calculated from the plasma volume. total scatter of values for blood glucose concentration and total plasma glucose was greater in edelsc ...19751200747
[lactic acid content of blood plasma in domestic swine of various breeds during physical exertion].lactic acid was determined by an enzymic method in plasma samples taken from 20 pigs of the german edelschwein, german landrace, german saddleback and edelschwein/landrace crosses before, during and after being made to run on a band moving at 1.3 metres/second for ten minutes, at 10 degrees c and relative humidity of 65-75%. a special method was used to assess the degree of exertion. the lactic acid curve showed that edelschwein and german saddlebacks had a low regulatory capacity while german l ...19751200746
legionnaires' disease with severe hypoxemia and saddleback fever.in the case of legionnaires' disease described, severe respiratory problems necessitated mechanical ventilatory support, tracheal intubation, and positive end-expiratory pressure. fever was eliminated with erythromycin therapy but returned after five days, and lung infiltrates spread. after supplementary treatment with other antibiotics and methylprednisolone sodium succinate, both the fever and the infiltrates disappeared. we feel that the multisystem involvement and the recrudescence of fever ...19817010336
sex change in a coral-reef fish: dependence of stimulation and inhibition on relative size.the removal of a single dominant individual has been shown to trigger a sex change in some coral-reeffish. in the saddleback wrasse (thalassoma duperrey), however, female-to-male sex change requires visual stimulation from smaller conspecifics. this change is not dependent on the sex or color of the stimulus fish and can be inhibited by larger conspecifics. on the reef, a female probably changes sex when the relative numbers of larger and smaller conspecifics change within her home range.198317830959
contact urticaria and allergic contact dermatitis to the saddleback caterpillar with histologic correlation. 19863771048
teambuilding: it starts at the top--of a tree?management experts say that teamwork begins at the top--with senior executives. for senior executives at the saddleback memorial medical center, laguna hills, ca, teamwork improvement started last march at the top of a tall pine tree. the saddleback team's deeds of daring were part of a sophisticated four-and-a-half-day training session at a special camp in the california mountains. the program challenged the hospital group to move beyond its current levels of teamwork.19902227903
primary invasive carcinoma of the vagina.a retrospective review was conducted of 53 women with invasive carcinoma of the vagina and without documented exposure to diethylstilbestrol who were seen at the university of california irvine medical center, long beach memorial medical center, and saddleback memorial medical center from 1976-1988. forty-seven (89%) had squamous cell carcinoma and six (11%) adenocarcinoma. thirty-seven (70%) were treated with whole-pelvis irradiation and brachytherapy, nine with surgery alone, and the other sev ...19902216195
functional health patterns: the postanesthesia care unit's approach to identification.functional health patterns, designed by marjorie gordon rn, phd, faan, have become an integral part of nursing documentation. these allow for the identification of potential problems that may occur during a patient's hospitalization. hence, a nursing diagnosis is formulated and communicated. this is usually accomplished via nursing care plans. the purpose of this article is to provide a brief discussion on the evolution of functional health patterns and nursing diagnosis. second, the adaptation ...19902355363
trichobezoars in two saddleback tamarins (saguinus fuscicollis).two captive-born saddleback tamarins (saguinus fuscicollis) died unexpectedly in the primate colony at the peruvian primatological project. at necropsy, a firm, mobile, oblong, obscure mass was discovered in the stomach of each. they were removed and determined to be trichobezoars.19902110980
locomotor design of dolphin vertebral columns: bending mechanics and morphology of delphinus delphis.the primary skeletal structure used by dolphins to generate the dorsoventral bending characteristic of cetacean swimming is the vertebral column. in the vertebral column of the saddleback dolphin delphinus delphis, we characterize the static and dynamic mechanical properties of the intervertebral joints, describe regional variation and dorsoventral asymmetries in mechanical performance, and investigate how the mechanical properties are correlated with vertebral morphologies. using a bending mach ...19979023994
saddleback memorial issues annual "quality report card" to grade itself in private--and in public. 199710173001
at saddleback memorial, care maps detail birth process interventions, cutting c-section rate and raising vbacs. 199710167182
adrenal cortical epithelial cysts in two saddleback tamarins (saguinus fuscicollis).adrenal cysts of epithelial origin were found incidentally in the adrenal cortical tissues of two adult female saddleback tamarins. in one case, a small cluster of minor cysts was located at the cortico-medullary border. the cysts were filled with a periodic acid-schiff (pas)-positive, amorphous substance and lined by a cuboidal pas-negative epithelium, which resembled morphologically the ascending henle's loops of the kidney. these microcysts were thought to be mesonephric remnants. in the seco ...19989749363
saddleback fever due to human granulocytic ehrlichiosis. 19989500331
obstat: benchmarking for improvement in obstetrics.a detailed database containing information on patients and practice patterns can be a positive force in efforts to lower cesarean rates. women's hospital at saddleback memorial medical center in laguna hills, ca, utilizes an in-house, custom database, known as obstat, to collect and store obstetrical clinical data. use of obstat has correlated positively with a reduction in cesarean rates at women's hospital.199910557759
body surface distribution and response to drugs of st segment elevation in brugada syndrome: clinical implication of eighty-seven-lead body surface potential mapping and its application to twelve-lead electrocardiograms.body surface distribution and magnitude of st segment elevation and their reflection in 12-lead ecgs have not been clarified in brugada syndrome.200010809492
detection of green turtle herpesviral sequence in saddleback wrasse thalassoma duperrey: a possible mode of transmission of green turtle fibropapilloma.samples of dna were prepared from various tissues and organs (including snout, gill, eye, brain, heart, liver, gut content, intestine, swim bladder, spleen, gallbladder, spinal cord, gonad, and muscle) of six healthy appearing reef cleaner fish, saddleback wrasses thalassoma duperrey, captured from a cleaning station in north kaneohe bay, oahu, hawaii. the dna samples were tested for evidence of green turtle herpesvirus infection by nested polymerase chain reaction (pcr). green turtle herpesvira ...200028880781
abundance, diversity, and patterns of distribution of primates on the tapiche river in amazonian peru.this work presents data on the relative diversity, abundance, and distribution patterns of primates in a 20 km2 area of the tapiche river in the peruvian amazon. population data were collected while the study area was both inundated and dry (march to september 1997) using conventional line-transect census techniques. survey results reflected the presence of 11 primate species, but population parameters on only eight of the species will be presented, including saddleback tamarins (saguinus fuscic ...200111376449
phylogeography and history of giant galápagos tortoises.we examined the phylogeography and history of giant galápagos tortoise populations based on mitochondrial dna sequence data from 161 individuals from 21 sampling sites representing the 11 currently recognized extant taxa. molecular clock and geological considerations indicate a founding of the monophyletic galápagos lineage around 2-3 million years ago, which would allow for all the diversification to have occurred on extant islands. founding events generally occurred from geologically older to ...200212449492
dengue fever: diagnostic importance of a camelback fever pattern.we present a case of imported dengue fever in a 52-year-old man acquired during a recent trip to ecuador. fever in a returning traveler from tropical areas often presents a diagnostic problem for clinicians. our patient presented with severe arthralgias and myalgias and had a camelback/saddleback fever pattern accompanied by relative bradycardia, which was a clue to the diagnosis. he had conjunctival suffusion and the truncal rash, but adenopathy was not present. he also had a generalized headac ...200314652535
intravenous administration of class i antiarrhythmic drug induced t wave alternans in an asymptomatic brugada syndrome patient.a 53-year-old man with an abnormal ecg was referred to the nihon university school of medicine. the 12-lead ecg showed right bundle branch block and saddleback-type st elevation in leads v1-v3 (brugada-type ecg). signal-averaged ecg showed positive late potentials. double ventricular extrastimuli (s1: 500 ms, s2: 250 ms, s3: 210 ms) induced vf. amiodarone (200 mg/day) was administered for 6 months and programmed ventricular stimulation was repeated. vf was induced again by double ventricular sti ...200312930508
the effect of colour vision status on the detection and selection of fruits by tamarins (saguinus spp.).the evolution of trichromatic colour vision by the majority of anthropoid primates has been linked to the efficient detection and selection of food, particularly ripe fruits among leaves in dappled light. modelling of visual signals has shown that trichromats should be more efficient than dichromats at distinguishing both fruits from leaves and ripe from unripe fruits. this prediction is tested in a controlled captive setting using stimuli recreated from those actually encountered by wild tamari ...200312909697
leaders of progressions in wild mixed-species troops of saddleback (saguinus fuscicollis) and mustached tamarins (s. mystax), with emphasis on color vision and sex.leadership of travel progression is an important aspect of group living. it is widely believed that trichromacy evolved to facilitate the detection and selection of fruit in the dappled light of a forest. further, it has been proposed that in new world primate species, which typically contain a range of color vision phenotypes, at least one female in a group will be trichromatic (i.e., having three types of visual pigment, in contrast to the two types of pigment found in dichromatic individuals) ...200314669267
monoamines stimulate sex reversal in the saddleback wrasse.monoamine neurotransmitters (norepinephrine, dopamine, and serotonin) play an important role in reproduction and sexual behavior throughout the vertebrates. they are the first endogenous chemical signals in the regulation of the hypothalamo-pituitary-gonadal (hpg) axis. in teleosts with behavioral sex determination, much is known about behavioral cues that induce sex reversal. the cues are social, processed via the visual system and depend on the ratio of females to males in the population. the ...200312606271
monoaminergic changes associated with socially induced sex reversal in the saddleback wrasse.the process of sex reversal in fishes is socially mediated and requires a total reorganization of the hypothalamo-pituitary-gonadal axis. when the ratio of males to females in a population of saddleback wrasse (thalassoma dupperrey) is too low, the largest female becomes male over the course of 6 to 8 weeks. this event requires the conversion of external social cues into internal chemical cues. in an attempt to investigate the role monoamines might play in this process, two females were housed t ...200312763086
effects of glucose-induced insulin secretion on st segment elevation in the brugada syndrome.st segment elevation in patients with brugada syndrome is known to fluctuate occasionally, influenced by multiple factors. insulin has been shown to affect qt dispersion in healthy volunteers, as well as result in abnormality of ventricular repolarization in patients with congenital long qt syndrome.200312716104
novel pore mutation in scn5a manifests as a spectrum of phenotypes ranging from atrial flutter, conduction disease, and brugada syndrome to sudden cardiac death.the purpose of this study was to determine the clinical and biophysical characteristics of a novel scn5a mutation.200415851228
manifestation of brugada syndrome after pacemaker implantation in a patient with sick sinus syndrome.a 49-year-old woman experienced syncope 10 months after ddd pacemaker implantation for sick sinus syndrome. ecg revealed abnormal st elevation in leads v1 to v3 during a paced rhythm. multifocal premature ventricular contractions followed by ventricular fibrillation were documented. saddleback-type st elevation was confirmed after a mode change to aai. the diagnosis of brugada syndrome was made, and the ddd pacemaker was upgraded to an implantable cardioverter defibrillator. brugada syndrome can ...200415574187
prevalence and prognosis of subjects with brugada-type ecg pattern in a young and middle-aged finnish population.the purpose of this study was (1) to determine the prevalence of brugada syndrome ecg abnormalities ("brugada sign") in two finnish populations and (2) to evaluate the natural course of subjects with the "brugada sign".200415140536
prevalence of the brugada electrocardiographic pattern at the medical center of louisiana in new orleans.since 1992 the brugada syndrome has gained recognition as a cause of ventricular fibrillation. the syndrome was originally described in patients with the diagnostic triad of (1) right bundle branch block, (2) an electrocardiogram (ecg) with persistent st-segment elevation in leads v1, v2, and v3, and (3) sudden cardiac death. two different types of st-segment elevation, coved and saddleback, have been described. all patients originally described had structurally normal hearts. the definition of ...200414748485
a nursing data base for initial patient assessment.the introduction of nursing diagnoses at saddleback memorial medical center, laguna hills, ca, resulted in the nursing process becoming the basis for the documentation system. however, the medical model or body system remained the organizational structure for nursing data collection and narrative charting. the need for a model that would aid in identification and treatment of illness and not negatively affect the nursing process was the impetus behind the selection of gordon's functional health ...20042003105
mechanism of st elevation and ventricular arrhythmias in an experimental brugada syndrome model.although phase 2 reentry is said to be responsible for initiation of ventricular tachycardia (vt) in brugada syndrome, information about the activation sequence during vt is limited.200414662710
relative ileal amino acid flows and microbial counts in intestinal effluents of goettingen minipigs and saddleback pigs are not different.we explored the suitability of goettingen minipigs as models to measure ileal aa digestibility and evaluate dietary proteins for conventional pigs. further, a potential for secondary ileal microbial colonization 5 mo after establishing end-to-end ileorectal anastomosis was investigated. goettingen minipigs (bw 18 kg) and saddleback pigs (bw 27 kg) fitted with end-to-end ileorectal anastomosis were fed six diets based on barley and oilseed meals and three diets based on wheat and milk powder diff ...200415309944
spontaneous onset of ventricular fibrillation in brugada syndrome with j wave and st-segment elevation in the inferior leads.we report the case of a 52-year-old man with variant brugada syndrome who was successfully resuscitated from ventricular fibrillation (vf). resting ecg showed j wave and st-segment elevation in the inferior leads but no coved or saddleback st-segment elevation in the right precordial leads. pilsicainide infusion provoked coved-type st-segment elevation in the right precordial leads and mild st-segment elevation 80 ms after the j point in the inferior leads. during an emergency, 12-lead ecg showe ...200515851273
propranolol intoxication revealing a brugada syndrome.this is the first report of brugada syndrome revealed by beta-blocker intoxication. a 24-year-old healthy man ingested propranolol (2.28 g) to commit suicide. after early gastric lavage, electrolytes, cardiac enzymes, chest x-ray, and echocardiography were normal. dosages of psychotropic drugs were negative. ecg showed a typical coved-type pattern of brugada syndrome. follow-up showed partial ecg normalization of the discrete saddleback-type pattern. the ajmaline- test confirmed brugada syndrome ...200515817098
spontaneous alternans in brugada ecg morphology.a 23-year-old man presented with sick sinus syndrome and brugada-like ecg pattern. coved type ecg (type 1) converted to saddleback configuration (type 2) when r-r interval decreased and it changed to coved type pattern with increasing r-r cycle length. during stable heart rate, there was no change in brugada ecg pattern. the r-r interval effect on these patterns can be explained by intensity or kinetics of ion currents and autonomic tone.200616755343
frequency of brugada-type ecg pattern (brugada sign) in southern turkey.the frequency of brugada sign was found to differ among ethnic groups. yet, there is no data regarding the prevalence of brugada syndrome and sign in our country. the aim of this study was to determine the frequency of a brugada-type electrocardiogram (ecg) pattern in southern turkey. a total of 1,238 subjects (males, 671, females, 567) were included in the study. the previously archived ecgs of 807 subjects without any evidence of structural heart disease were chosen randomly and evaluated. in ...200616960409
brugada-like early repolarisation pattern associated with acute pericarditis.two cases of acute pericarditis presented with interesting electrocardiograms resembling brugada-like or early repolarisation patterns. this report emphasises that proper interpretation of the electrocardiogram in patients with st-segment elevation assists the clinician in arriving at the correct diagnosis in making appropriate diagnostic and therapeutic decisions, and also that the saddleback-type st-segment elevation cannot be a sensitive finding for the brugada syndrome.200617130585
source of radium in a well-water-augmented florida lake.a study of the lake waters of saddleback lake, florida was undertaken with the goal of determining the source of elevated radium activities in the lake. four radium isotopes, (226)ra, (228)ra, (223)ra and (224)ra, were measured and activities of all the four radium isotopes were substantially greater in the well water used to augment the lake as compared to the lake waters. in the surface water, radium activities were highest close to the well used for augmentation in the initial sampling. activ ...200616730106
reconstruction of the nasal dorsum with autologous rib cartilage.the authors present their experience with the correction of deformities of the nasal saddleback using rib cartilage grafts. they present a review of international literature on this topic, analyzing 33 patients selected from 452 cases of rhinoplasties performed between january 1990 and december 2004 at the department of plastic and reconstructive surgery of the university of rome "tor vergata." nasal saddleback is one of the most complicated defects to correct surgically. it can be a consequence ...200616508354
brugada-like electrocardiographic pattern: a challenge for the clinician.a right bundle branch block with st-segment elevation in the v1-v3 leads in characteristic coved or saddleback configuration may be encountered as an incidental finding. however, not all patients with a brugada-like electrocardiographic pattern are affected by the brugada syndrome; in fact, this pattern may also be found in healthy individuals. whether symptomatic patients affected by the syndrome are at a high risk of developing life-threatening ventricular arrhythmias and should immediately re ...200616378878
historic and contemporary levels of genetic variation in two new zealand passerines with different histories of decline.we compared historic and contemporary genetic variation in two threatened new zealand birds (saddlebacks and robins) with disparate bottleneck histories. saddlebacks showed massive loss of genetic variation when extirpated from the mainland, but no significant loss of variation following a severe bottleneck in the 1960s when the last population was reduced from approximately 1000 to 36 birds. low genetic variation was probably characteristic of this isolated island population: considerably more ...200717714320
familial clustering of lone atrial fibrillation in patients with saddleback-type st-segment elevation in right precordial leads.we recently identified a large family with a high prevalence of lone atrial fibrillation (af) and saddleback-type st-segment elevation in leads v(1-3), without a history of ventricular arrhythmias or syncope. on the basis of this finding, we studied whether there is a relationship between saddleback st-elevation and lone af.200717242012
what's eating you? saddleback caterpillar (acharia stimulea). 200717944167
long-term patterns of sleeping site use in wild saddleback (saguinus fuscicollis) and mustached tamarins (s. mystax): effects of foraging, thermoregulation, predation, and resource defense constraints.sleeping sites are an important aspect of an animal's ecology given the length of time that they spend in them. the sleep ecology of wild saddleback and mustached tamarins is examined using a long-term data set covering three mixed-species troops and 1,300+ tamarin nights. seasonal changes in photoperiod accounted for a significant amount of variation in sleeping site entry and exit times. time of exit was more closely correlated with sunrise than time of entry was with sunset. both species ente ...200717632801
prey foraging of red titi monkeys, callicebus cupreus, in comparison to sympatric tamarins, saguinus mystax and saguinus fuscicollis.we compared the prey capture strategies of red titi monkeys, callicebus cupreus, with those of sympatric mustached, saguinus mystax, and saddleback tamarins, saguinus fuscicollis, to examine whether animal prey is important in niche differentiation between these neotropical primates. we collected data on strata and substrate use during foraging, on prey searching and capturing, and on prey type of two c. cupreus groups and one group each of s. mystax and s. fuscicollis during a 5-month field stu ...200817787001
fever, headache, and myalgias after deployment to the philippines.classic dengue fever presents with a triad of fever, headache, and rash. a "saddleback" fever pattern, morbilliform rash with islets of sparing after apyrexia, and hematological/hepatic abnormalities are common findings. as the most common arbovirus infection, dengue is a significant health threat to deployed military forces worldwide. preventive measures such as personal protective equipment and repellants should be employed by individuals and other preventive measures should be considered for ...200819149337
serous cells in the parotid glands of two species of tamarins: polarized secretory granules.the parotid glands of two species of tamarins were examined by electron microscopy. endpiece cells are typical in appearance, with an extensive rough endoplasmic reticulum, prominent golgi apparatuses, and numerous serous granules. in the saddleback tamarin, the secretory granules contain a dense spherule pressed against the inner aspect of the limiting membrane, leading to a surface bulge. during the course of merocrine secretion (a form of exocytosis), such morphologically polarized granules a ...200818780306
st-t wave changes in a patient complicated with vasospastic angina and brugada syndrome: differential responses to acetylcholine in right and left coronary artery.a 49-year-old man with chest pain and syncope presented saddleback or occasionally coved type st elevation in v1-v3. coronary spasm in the left anterior descending artery was induced by acetylcholine injection and st elevation changed from saddleback to coved type in v2-v3 together with st depression in v4-v5, whereas acetylcholine injection into the right coronary artery did not provoke spasm, but induced augmented and coved type st elevation in v2 without st-t changes in v4-v5. these electroca ...200818484164
no evidence for loss of genetic variation following sequential translocations in extant populations of a genetically depauperate species.repeated population bottlenecks can lead to loss of genetic variation and normally should be avoided in threatened species to preserve evolutionary potential. we examined the effect of repeated bottlenecks, in the form of sequential translocations, on loss of genetic variation in a threatened passerine, the saddleback (philesturnus carunculatus carunculatus), a species that has recovered from a remnant population with historically low levels of genetic variation. although a slight but nonsignifi ...200817986194
the brugada syndrome.the brugada syndrome is an inherited cardiac disorder initially described in 1992 by pedro and josep brugada, with variable electrocardiographic features characteristic of right bundle-branch block, persistent st-segment elevation in the precordial leads (vi-v3) at rest and sudden cardiac death. the genetic abnormalities that cause brugada syndrome have been linked to mutations in the ion channel gene scn5a which encodes for the alpha-subunit of the cardiac sodium channel. a consensus conference ...200920128157
long-term prognosis of probands with brugada-pattern st-elevation in leads v1-v3.the prognosis of patients with saddleback or noncoved type (non-type 1) st-elevation in brugada syndrome is unknown. the purpose of this study was to clarify the long-term prognosis of probands with non-type 1 ecg and those with coved (type 1) brugada-pattern ecg.200919843917
response to intravenous ajmaline: a retrospective analysis of 677 ajmaline challenges.the diagnostic type i ecg in brugada syndrome (bs) is often concealed and fluctuates between the diagnostic and non-diagnostic pattern. challenge with intravenous ajmaline is used to unmask the diagnostic brugada ecg. the aim of this study was to evaluate the safety of the test and to identify predictors for the response to an intravenous ajmaline challenge.200919589796
variability of the diagnostic ecg pattern in an icd patient population with brugada syndrome.the spontaneous presence of a coved-type ecg is considered as an important risk factor in brugada syndrome. however, diagnosis making and risk stratification may be hampered by the dynamic nature of the ecg abnormalities. the objective of this study was to determine the variability and predictive value of the electrocardiogram in brugada patients implanted with a cardioverter-defibrillator (icd).200918775043
long-term electrocardiographic follow-up from childhood of an adult patient with brugada syndrome associated with sick sinus syndrome.we had the unique opportunity of following the electrocardiographic (ecg) course of a 13-year-old male with sinus dysfunction and atrial flutter who subsequently developed a brugada-type ecg pattern associated with sick sinus syndrome at 25 years old. family history showed that the patient's mother and maternal grandfather suddenly died while sleeping at night. when the patient was 13 years old, he lost consciousness after running a marathon. the patient was diagnosed with sinus dysfunction and ...200919075525
a transatlantic caterpillar.saddleback caterpillar sting has been very rarely reported in european countries. we report a french case of a stung toddler.200919287278
mutations in sodium channel beta1- and beta2-subunits associated with atrial fibrillation.we and others have reported mutations in the cardiac predominant sodium channel gene scn5a in patients with atrial fibrillation (af). we also have reported that scn1b is associated with brugada syndrome and isolated cardiac conduction disease. we tested the hypothesis that mutations in the 4 sodium channel beta-subunit genes scn1b-scn4b contribute to af susceptibility.200919808477
exercise-induced ventricular tachycardia associated with asymptomatic brugada syndrome in a patient with urinary bladder stone.it is well-known that autonomic nerve modulation has an important role in the occurrence of ventricular tachyarrhythmias in brugada syndrome. a 59-year-old man underwent cardiac evaluation before surgery for urinary bladder stone. he had no cardiac complaints and the only coronary risk factor was heavy smoking. the electrocardiogram showed a saddleback type st-segment elevation in leads v1-v2, and left axis deviation. during exercise stress test, ventricular tachycardia with a left bundle branch ...200919404036
genotype-phenotype correlation in tissue models of brugada syndrome simulating patients with sodium and calcium channelopathies.genetic defects in the sodium channel or in the calcium channel have been identified in patients with brugada syndrome (bs). however, the differences in their genotype-phenotype correlations are still unclear.201020206324
the use of ultrasound to detect small-for-gestational-age infants in patients with elevated human chorionic gonadotropin on maternal serum screening.we evaluated serial sonography for the antenatal detection of small-for-gestational-age (sga) infants in pregnancies with elevated human chorionic gonadotropin (hcg) levels on midtrimester triple-marker screen. a retrospective cohort study was performed at saddleback memorial medical center where serial ultrasounds from 26 weeks to delivery are generally recommended for patients with hcg levels >2.0 multiple of the median (mom). from 1999 to 2007, 659 subjects were identified for analysis. the i ...201019742421
the influence of human settlements on the parasite community in two species of peruvian tamarin.although there is a growing recognition that the transfer of diseases between humans and non-human primates can be of great significance for conservation biology, there have been only a few studies focusing on parasites. in this study, saddleback (saguinus fuscicollis) and moustached tamarin (saguinus mystax) from the rainforest of the peruvian lowlands were used as models to determine helminth parasite associations between canopy-dwelling primate species and a nearby human settlement. the human ...201020025821
concurrent avian malaria and avipox virus infection in translocated south island saddlebacks (philesturnus carunculatus carunculatus).outbreaks of mortality in south island saddlebacks (philesturnus carunculatus carunculatus) that had been translocated to two offshore islands in the marlborough sounds of new zealand were investigated during the summers of 2002 and 2007. both outbreaks were associated with a severe decrease in numbers of saddlebacks of up to 60% of approximately 200 birds. clinical and pathological findings: many of the surviving birds were in poor condition, and had skin lesions on the legs and head. necropsy ...201020676161
the range of the golden-mantle tamarin, saguinus tripartitus (milne-edwards, 1878): distributions and sympatry of four tamarins in colombia, ecuador, and northern peru [corrected].a detailed understanding of the range of the golden-mantle tamarin, saguinus tripartitus (milne edwards, 1878), in amazonian peru and ecuador is of particular relevance, not only because it is poorly known but also because it was on the basis of its supposed sympatry with the saddleback tamarin (s. fuscicollis lagonotus) that thorington (am j primatol 15:367-371, 1988) argued that it is a distinct species rather than a saddleback tamarin subspecies, as was believed by hershkovitz (living new wor ...201020878203
functions of intermittent locomotion in mustached tamarins (saguinus mystax).many animals interrupt their moving with brief pauses, which appear to serve several different functions. we examined the function of such intermittent locomotion in wild living mustached tamarins (saguinus mystax), small arboreal new world primates that form mixed-species groups with saddleback tamarins (saguinus fuscicollis). we investigated how different environmental and social factors affect pausing during locomotion and used these data to infer the function of this behavior. as measures of ...201020949115
winter predation of diapausing cocoons of slug caterpillars (lepidoptera: limacodidae).predators exert strong top-down pressure on herbivorous insects, but research on how predators affect herbivore fitness often focuses on the more active juvenile and adult life stages while ignoring the pupal or cocoon life stage. few studies have investigated predation of lepidopteran pupae or cocoons and even fewer have investigated species that are not forest pests. here we present a study on overwinter survival for two moth species in the family limacodidae, a group of polyphagous species fo ...201022182555
sensitivity and specificity of sodium channel blocking test in the diagnosis of brugada syndrome.the ecg features of brugada syndrome are dynamic and frequently concealed. sodium channels blockers are widely used to unmask the brugada electrocardiographic (ecg) pattern. the sensitivity and specificity of i(na) channel blocking test varies significantly. a negative i(na) blocking test does not exclude the presence of a scn5a mutation, which is responsible for the phenotype of brugada syndrome. herein, we describe the case of a 65-years-old asymptomatic male who underwent a i(na) channel bloc ...201019141363
ischemia-induced brugada-type st-segment alternans and brugada syndrome.the mechanisms of brugada-type electrocardiographic (ecg) pattern remain unclear.201019345432
vigilance of mustached tamarins in single-species and mixed-species groups-the influence of group composition.species that participate in mixed-species groups (msg) may have complementary roles in antipredator strategies. we studied vigilance in mustached tamarins (saguinus mystax), small arboreal primates that form stable mixed-species groups with saddleback tamarins (saguinus fuscicollis), in order to examine how the direction of vigilance changes with different species group compositions and whether the division of labor between the two species can be confirmed. we did so by comparing quantitative an ...201020119489
contemporary cultural evolution of a conspecific recognition signal following serial translocations.the divergence of conspecific recognition signals (crs) among isolated populations facilitates the evolution of behavioral barriers to gene flow. the influence of crs evolution on signal effectiveness in isolated populations can be assessed by testing the salience of changes in crs from surviving ancestral populations but founder events are rarely detected. the population history of the north island (ni) saddleback philesturnus rufusater is absolutely known following conservation translocations ...201020394665
can overmarking be considered as a means of chemical mate guarding in a wild callitrichid?mate guarding is a male strategy to monopolize matings and thus to ensure paternity. since in callitrichids female reproductive status is advertised by scent marks, one may expect mate guarding by chemical means. we addressed this question during an episode of consortship observed in a polyandrous trio of wild saddleback tamarins (saguinus fuscicollis). during consortship, the consort male was the only one to allomark the female. scent marking frequency decreased for all individuals, although th ...201020975281
vigilance in a cooperatively breeding primate.collective vigilance is considered a major advantage of group living in animals. we investigated vigilance behavior in wild mustached tamarins (saguinus mystax), small, arboreal, cooperatively breeding new world primates that form stable mixed-species groups with saddleback tamarins (saguinus fuscicollis). we aimed 1) to investigate whether vigilance patterns change according to individual activity and 2) to examine whether there is a social component of vigilance in their cooperative and nonagg ...201020174438
proarrhythmic ecg deterioration caused by myocardial ischemia of the conus branch artery in patients with a brugada ecg pattern.the brugada-type electrocardiogram (ecg) is characterized by st-segment elevation in the right precordial ecg leads and has been reported to have the potential of sudden death. right ventricular outflow tract supplied from the conus branch of the coronary artery (cb) is considered as the anatomopathologic substrate of brugada syndrome. we experienced two asymptomatic patients with a saddleback brugada-type ecg who exhibited a dynamic ecg conversion to a coved type following a ventricular fibrill ...201120353416
pilot project to improve discharge process.the care management department at saddleback memorial hospital in laguna hills, ca, is piloting a standardized work flow process for discharging patients. process identifies who is responsible for what after discharge orders are written. discharge process is tracked on an electronic board. process eliminates duplications and omissions.201121789908
increased intraatrial conduction abnormality assessed by p-wave signal-averaged electrocardiogram in patients with brugada syndrome.atrial fibrillation (af) is observed in patients with brugada syndrome (bs), especially those showing coved-type electrocardiogram (ecg) pattern. using p-wave signal-averaged ecg (p-sae), we investigated whether increased intraatrial conduction abnormality contributed to af generation in bs patients.201121605130
[concealed brugada syndrome that became apparent incidentally during atrial fibrillation therapy].a 31-year-old male patient was admitted to the emergency department with acute atrial fibrillation. after diltiazem infusion, a single oral dose of 600 mg propafenone was given to the patient for medical cardioversion. approximately four hours later, sinus rhythym was restored. re-evaluation of the admission ecg revealed right bundle branch block and saddleback-type st-segment elevation of about 2 mm in v1-2 leads. following propafenone, this type 2 brugada ecg pattern turned to the coved type 1 ...201121430424
study of the carapace shape and growth in two galápagos tortoise lineages.galápagos tortoises possess two main shell forms, domed and saddleback, that correlate with the biogeographic history of this species group. however, the lack of description of morphological shell variation within and among populations has prevented the understanding of the contribution of evolutionary forces and the potential role of ontogeny in shaping morphological shell differences. here, we analyze two lineages of galápagos tortoises inhabiting santa cruz island by applying geometric morpho ...201121246597
the equivocal relationship between territoriality and scent marking in wild saddleback tamarins (saguinus fuscicollis).researchers have often assumed that scent marking serves a territorial function in callitrichines, although some controversy exists. to fulfill such a function, scent marks should 1) prevent intrusions, 2) ensure access to feeding resources, 3) enable avoidance of intergroup encounters, or 4) play an important role in the aggressive encounters between groups. we studied 13 saddleback tamarins (saguinus fuscicollis) belonging to 3 free-ranging groups, which formed mixed-species troops with mousta ...201121892237
the phylogenetic analysis of avipoxvirus in new zealand.avipoxvirus is known to be endemic in new zealand and it is a cause of ongoing mortalities in the endangered black robin and shore plover populations. there is no information on the strains of avipoxvirus occurring in new zealand and their likely origin or pathogenicity. this study was designed to identify the phylogenetic relationships of pathogenic avipoxvirus strains infecting introduced, native, and endemic bird species in new zealand. avipoxvirus 4b core protein gene was detected in tissue ...201121316164
Presence and seasonal prevalence of Plasmodium spp. in a rare endemic New Zealand passerine (tieke or Saddleback, Philesturnus carunculatus).The conservation and management of Saddlebacks (Philesturnus carunculatus) and other New Zealand birds, currently relies on the translocation of individuals to predator-free sites. Avian malaria has been identified as one of the diseases to be tested for prior to translocations in New Zealand, with the aim of translocating disease-free individuals. We describe avian malaria lineages and their seasonal prevalence in 2007-2008 in Saddlebacks from Mokoia Island, a source of birds for translocations ...201122102656
territorial polemics: a response to roberts.our recent paper lledo-ferrer et al. (international journal of primatology 32: 974-991, 2011) questioned the classic view of territoriality and chemical communication in wild callitrichids, saddleback tamarins (saguinus fuscicollis). we suggested that rather than defending a territory or resources, chemical communication was more likely to be a way of exchanging reproductive information between groups. roberts (international journal of primatology 33, 2012). challenged this interpretation, consi ...201222865945
brugada pattern mimicking acute coronary syndrome in a febrile state.the brugada type pattern is characterized by a coved or saddleback shaped st-segment elevation in the right precordial leads (v1-v3) on a surface 12 lead electrocardiogram (ecg). this pattern can be seen spontaneously, induced by sodium channel blocking drugs or rarely by hyperthermia. the mechanism is secondary to an alteration in the sodium channels induced by a febrile state. such ecg's could easily be mistaken for acute st segment elevation myocardial infarction and thus pose a unique clinic ...201222973684
the effects of translocation-induced isolation and fragmentation on the cultural evolution of bird song.understanding the divergence of behavioural signals in isolated populations is critical to knowing how certain barriers to gene flow can develop. for many bird species, songs are essential for conspecific recognition and mate choice. measuring the rate of song divergence in natural populations is difficult, but translocations of endangered birds to isolated islands for conservation purposes can yield insights, as the age and source of founder populations are completely known. we found significan ...201222590997
characterization of mhc class ii b polymorphism in bottlenecked new zealand saddlebacks reveals low levels of genetic diversity.the major histocompatibility complex (mhc) is integral to the vertebrate adaptive immune system. characterizing diversity at functional mhc genes is invaluable for elucidating patterns of adaptive variation in wild populations, and is particularly interesting in species of conservation concern, which may suffer from reduced genetic diversity and compromised disease resilience. here, we use next generation sequencing to investigate mhc class ii b (mhciib) diversity in two sister taxa of new zeala ...201323686447
coccidia species in endemic and native new zealand passerines.new zealand native passerines are hosts to a large variety of gastrointestinal parasites, including coccidia. coccidian parasites are generally host-specific, obligate intracellular protozoan parasites. in passerine birds, members of the genus isospora are most common. under natural conditions, these parasites seldom pose a threat, but stressors such as quarantine for translocation, overcrowding, or habitat changes may cause an infection outbreak that can severely affect wild populations. althou ...201323468142
saddleback deformities in yellowfin bream, acanthopagrus australis (günther), from south east queensland. 201323121304
correlation of saddleback syndrome with deformities of the pelvic fins and lateral line in european sea bass, dicentrarchus labrax. 201325141647
facilitative effects of group feeding on performance of the saddleback caterpillar (lepidoptera: limacodidae).gregarious feeding by insect herbivores is a widely observed, yet poorly understood, behavioral adaptation. previous research has tested the importance of group feeding for predator deterrence, noting the ubiquity of aposematism among group-feeding insects, but few studies have examined the role of feeding facilitation for aggregates of insect herbivores. we tested the hypothesis that group feeding has facilitative effects on performance of the saddleback caterpillar, acharia stimulea clemens, a ...201424472205
usefulness of patient's history and non-invasive electrocardiographic parameters in prediction of ajmaline test results in patients with suspected brugada syndrome.the aim of the work was to assess the usefulness of patient's history and non-invasive electrocardiographic parameters in the prediction of ajmaline test results in patients with suspected brugada syndrome.201425395941
avian malaria in new zealand.avian malaria parasites of the genus plasmodium have the ability to cause morbidity and mortality in naïve hosts, and their impact on the native biodiversity is potentially serious. over the last decade, avian malaria has aroused increasing interest as an emerging disease in new zealand with some endemic avian species, such as the endangered mohua (mohua ochrocephala), thought to be particularly susceptible. to date, avian malaria parasites have been found in 35 different bird species in new zea ...201424313228
long-term pharmacological therapy of brugada syndrome: is j-wave attenuation a marker of drug efficacy?we herein describe two patients with brugada syndrome in whom j-waves were successfully modified by drugs. case 1 was a 54-year-old man who presented with repeated ventricular fibrillations (vf) and j-point elevation in the right precordial and lateral leads. after administration of cilostazol (200 mg/d), j-waves disappeared and coved-type st-segment elevation changed to a saddleback-type for 25 months. case 2 was a 31-year-old man who presented with a vf storm and j-point elevation in the later ...201425030565
forest type affects prey foraging of saddleback tamarins, saguinus nigrifrons.callitrichids can persist in secondary forests where they may benefit from elevated prey abundance. however, how tamarins forage for prey in secondary forest compared to primary forest has not been examined. using scan and focal sampling, we compared prey foraging and capture success of two groups of saguinus nigrifrons in north-eastern peru: one ranging in primary forest, the other with access to a 10-year-old anthropogenic secondary forest. there was a trend for more prey search in the seconda ...201424687729
primary urinary bladder haemangiosarcoma in a captive saddleback tamarin (saguinus fuscicollis).a captive adult male saddleback tamarin, saguinus fuscicollis, was lethargic, unresponsive to its surrounding and died before medical care.201424784233
navigating in small-scale space: the role of landmarks and resource monitoring in understanding saddleback tamarin travel.recent studies of spatial memory in wild nonhuman primates indicate that foragers may rely on a combination of navigational strategies to locate nearby and distant feeding sites. when traveling in large-scale space, tamarins are reported to encode spatial information in the form of a route-based map. however, little is known concerning how wild tamarins navigate in small-scale space (between feeding sites located at a distance of ≤60 m). therefore, we collected data on range use, diet, and the a ...201424038234
high-throughput sequencing of fecal dna to identify insects consumed by wild weddell's saddleback tamarins (saguinus weddelli, cebidae, primates) in bolivia.the genus saguinus represents a successful radiation of over 20 species of small-bodied new world monkeys. studies of the tamarin diet indicate that insects and small vertebrates account for ∼16-45% of total feeding and foraging time, and represent an important source of lipids, protein, and metabolizable energy. although tamarins are reported to commonly consume large-bodied insects such as grasshoppers and walking sticks (orthoptera), little is known concerning the degree to which smaller or l ...201525369770
reply to pollock (2014) comments on 'saddleback deformities in yellowfin bream, acanthopagrus australis (günther), from south east queensland' by diggles (2013). 201525594432
comments on 'saddleback deformities in yellowfin bream, acanthopagrus australis (günther), from south-east queensland' by diggles (2013). 201525594243
[brugada ecg].the brugada syndrome (brs) is characterized by a typical electrocardiogram (ecg) pattern of right precordial st-segment elevation and the cardinal symptoms syncope and sudden cardiac death as clinical correlate of malignant ventricular arrhythmias in young adults without structural heart disease. the diagnosis of a type 1 brugada-ecg is based on the documentation of a coved-type (≥ 0.2 mv) st elevation followed by a negative t wave. the use of the ecg criteria postulated in the consensus of 2012 ...201526249049
relationships among and variation within rare breeds of swine.extinction of rare breeds of livestock threatens to reduce the total genetic variation available for selection in the face of the changing environment and new diseases. swine breeds facing extinction typically share characteristics such as small size, slow growth rate, and high fat percentage, which limit them from contributing to commercial production. compounding the risk of loss of variation is the lack of pedigree information for many rare breeds due to inadequate herd books, which increases ...201526440160
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