Publications

evolutionary history of the coccolithoviridae.	we recently determined the genome sequence of the coccolithoviridae strain emiliania huxleyi virus 86 (ehv-86), a giant double-stranded dna (dsdna) algal virus from the family phycodnaviridae that infects the marine coccolithophorid e. huxleyi. here, we determine the phylogenetic relationship between ehv-86 and other large dsdna viruses. twenty-five core genes common to nuclear-cytoplasmic large dsdna virus genomes were identified in the ehv-86 genome; sequence from eight of these genes were use ...	2006	16151186
locus-specific gene expression pattern suggests a unique propagation strategy for a giant algal virus.	emiliania huxleyi virus strain 86 is the largest algal virus sequenced to date and is unique among the phycodnaviridae since its genome is predicted to contain six rna polymerase subunit genes. we have used a virus microarray to profile the temporal transcription strategy of this unusual virus during infection. there are two distinct transcription phases to the infection process. the primary phase is dominated by a group of coding sequences (cdss) expressed by 1 h postinfection that are localize ...	2006	16840348
proteomic analysis of the ehv-86 virion.	emiliania huxleyi virus 86 (ehv-86) is the type species of the genus coccolithovirus within the family phycodnaviridae. the fully sequenced 407,339 bp genome is predicted to encode 473 protein coding sequences (cdss) and is the largest phycodnaviridae sequenced to date. the majority of ehv-86 cdss exhibit no similarity to proteins in the public databases.	2008	18346272
a unicellular algal virus, emiliania huxleyi virus 86, exploits an animal-like infection strategy.	emiliania huxleyi virus 86 (ehv-86) belongs to the family phycodnaviridae, a group of viruses that infect a wide range of freshwater and marine eukaryotic algae. phycodnaviridae is one of the five families that belong to a large and phylogenetically diverse group of viruses known as nucleocytoplasmic large dsdna viruses (ncldvs). to date, our understanding of algal ncldv entry is based on the entry mechanisms of members of the genera chlorovirus and phaeovirus, both of which consist of non-envel ...	2009	19474246
draft genome sequence of the coccolithovirus ehv-84.	the coccolithoviridae is a recently discovered group of viruses that infect the marine coccolithophorid emiliania huxleyi. emiliania huxleyi virus 84 (ehv-84) has a 160 -180 nm diameter icosahedral structure and a genome of approximately 400 kbp. here we describe the structural and genomic features of this virus, together with a near complete draft genome sequence (~99%) and its annotation. this is the fourth genome sequence of a member of the coccolithovirus family.	2011	22180805
draft genome sequence of the coccolithovirus emiliania huxleyi virus 203.	the coccolithoviridae are a recently discovered group of viruses that infect the marine coccolithophorid emiliania huxleyi. emiliania huxleyi virus 203 (ehv-203) has a 160- to 180-nm-diameter icosahedral structure and a genome of approximately 400 kbp, consisting of 464 coding sequences (cdss). here we describe the genomic features of ehv-203 together with a draft genome sequence and its annotation, highlighting the homology and heterogeneity of this genome in comparison with the ehv-86 referenc ...	2011	22106382