Publications

molecular genetic analyses of parapoxviruses pathogenic for humans.	the current members of the genus parapoxvirus are orf virus (orfv), bovine papular stomatitis virus (bpsv), pseudocowpoxvirus (pcpv) and parapoxvirus of red deer in new zealand (pvnz). bpsv and pcpv are maintained in cattle while orfv is maintained in sheep and goats, but all three are zoonoses. only the recently reported pvnz has yet to be recorded as infecting humans. tentative members of the genus are camel contagious ecthyma virus, chamois contagious ecthyma virus and sealpoxvirus. the separ ...	1997	9413523
detection and diagnosis of parapoxvirus by the polymerase chain reaction.	the genus parapoxvirus includes four members, bovine papular stomatitis virus (bpsv), pseudocowpox virus (pcpv), orf virus (orfv) and parapoxvirus of red deer in new zealand (pvnz). a set of primers for polymerase chain reaction (pcr) was designed to detect viral dna from cells infected with each of the four parapoxviruses. the set of primers resulted in the amplification of appropriately sized products from cells infected with bpsv, pcpv, orfv and pvnz, respectively. the pcr method was applied ...	2000	10680970
characterization of sealpox virus, a separate member of the parapoxviruses.	a disease outbreak characterized by lesions of the skin and mucosa of the oral cavity was recognized in harbor seals ( phoca vitulina) from the german north sea. using electron microscopy typical parapoxvirus particles were observed. the presence of parapoxvirus was confirmed by pcr and nucleotide sequencing of part of the putative major envelope protein coding gene. comparative sequence analysis revealed that the virus from seal is significantly different from the established parapoxvirus speci ...	2002	12111424
parapoxvirus of red deer in new zealand encodes a variant of viral vascular endothelial growth factor.	parapoxvirus of red deer in new zealand (pvnz), a species of the parapoxvirus genus, causes scabby lesions on the skin and the velvet of red deer. the three other species of the genus have each been shown to encode homologs of vascular endothelial growth factor (vegf). we report here that pvnz strain rd86 also encodes a vegf and that the predicted pvnz protein shows only 37-54% amino acid identity to vegfs encoded by the other species of the genus. despite this extensive sequence divergence, ass ...	2007	17109982
chemokine-binding proteins encoded by parapoxvirus of red deer of new zealand display evidence of gene duplication and divergence of ligand specificity.	parapoxvirus of red deer in new zealand (pvnz) is a species of the parapoxvirus genus that causes pustular dermatitis. we identified a cluster of genes in pvnz that encode three unique chemokine-binding proteins (cbps) namely orf112.0, orf112.3 and orf112.6. chemokines are a large family of molecules that direct cell trafficking to sites of inflammation and through lymphatic organs. the pvnz-cbps were analyzed by surface plasmon resonance against a broad spectrum of cxc, cc, xc and cx3c chemokin ...	2019	31293551
epitheliotropic infections in wildlife ruminants from the central alps and stelvio national park.	the mountain chain of the alps, represents the habitat of alpine fauna where the red deer (cervus elaphus) population is the outmost numerous, followed by the chamois (rupicapra rupicapra) and the alpine ibex (capra ibex) at higher altitudes. previous reports showed the circulation of epitheliotropic viruses, belonging to the families papillomaviridae and poxviridae, causing skin and mucosal lesions in wild ruminants of the stelvio national park, situated in the area. to deepen our knowledge on ...	2020	32426384