Publications

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on the identity of multiceps multiceps (leske, 1780), m. gaigeri hall, 1916, and m. serialis (gervalis, 1845), with a review of these and similar forms in man and animals. 194620244140
a survey of victorian canine and vulpine parasites; platyhelminthes other than taenia multiceps, taenia ovis and echinococcus graulossus. 194620290803
a survey of victorian canine and vulpine parasites; material and methods used in the investigation; taenia multiceps, taenia ovis and echinococcus granulosus. 194621028683
intra-medullary cyst of the spinal cord due to the cestode multiceps multiceps in the coenurus stage; report of a case. 194918124045
intra-medullary cyst of the spinal cord due to the cestode multiceps multiceps in the coenurus stage: report of a case. 194916810830
[a new host for the polycephalic cystic worms of taenia (multiceps) endothoracicus ja. d. kirchenblatt, 1948]. 195613342849
a critical study of the taxonomy of taenia pisiformis bloch, 1780; multiceps multiceps (leske, 1780); and hydatigera taeniaeformis batsch, 1786. 19655848820
comparative observations on infection rates of normal and anomalous taenia multiceps in laboratory mice. 19685641042
studies on carbohydrates in tissues and coenurus fluid of larval taenia multiceps from normal and alloxanized mice. 19685740545
[multiceps multiceps (leske 1780) in dogs in poland]. 19705529985
[current state of the diffusion of cerebral cenuriasis (coenurus of taenia multiceps multiceps) in sheep and humans in sardinia]. 19715152929
taenia multiceps larva from a gemsbok. 19724664320
letter: multiceps multiceps in early south australian flocks. 19751101875
localization of some enzymes in polycephalic larvae of two species of the genus multiceps (cestoda).the histochemical distribution of alkaline phosphatase (aip), acid phosphatase (acp) and nonspecific esterase (ne) has been determined in polycephalic larvae of the species multiceps multiceps leske, 1870 and m. endothoracicus kirschenblat, 1948. in the scolex anlages of both species, an activity of these enzymes has been determined in sites associated with growth and with the transport of metabolites. in a young larva of m. multiceps, the activity of aip, acp and ne was strong in the entire pro ...19761034589
coenurus infestation of eye and orbit.histopathologic examination of an eye with severe anterior uveitis and a whitish retrolental tumor in a 43-year-old woman, and of an orbital cystic tumor in a 2-year-old girl, showed the presence of coenurus, the bladderworm of multiceps multiceps. the single bladder of coenurus may contain hundreds of scoleces. intraocular coenurus is most often located in the subretinal space.1976945727
an attempt to treat the larval stage of taenia multiceps and a résumé of its neural and extraneural distribution in sheep. 1978754127
taenia hydatigena and taenia multiceps infections in snowdonia, u.k. ii. the role of hunting dogs and foxes as definitive hosts, and of sheep as intermediate hosts. 1979487054
taenia hydatigena and taenia multiceps infections in snowdonia, u.k. i. farm dogs as definitive hosts. 1979487053
racemose cysticercus in human brain. a case report.a case of invasion of the brain of a 48-year-old man, a native of louisiana, by a larval tapeworm is described. inasmuch as there were no scolices or rostellar hooks present the parasite was identified as a racemose cysticercus which could be either a sterile coenurus of taenia multiceps (= multiceps multiceps), taenia serialis (= multiceps serialis), or an aberrant cysticercus of taenia solium or of a different species of taenia. most of the parasite was removed surgically with a preoperative d ...19817258483
preliminary investigations into the immunization of lambs against infection with taenia multiceps metacestodes.two trials were carried out to investigate the protective value of various antigens in the immunization of lambs against taenia multiceps metacestode infections. the first trial involved groups of 5 or 6 lambs immunized with activated t. multiceps oncospheres; activated t. hydatigena oncospheres; t. multiceps coenurus fluid antigens, and two untreated control groups. all except one of the control groups were challenged orally with t. multiceps oncospheres 5 weeks later. the results of the trial ...19827201194
preliminary report on the stimulation of immunity to the larval stage of taenia multiceps.the efficacy of oncosphere secretory antigen (osa) in protecting sheep against the larval stage of taenia multiceps was assessed in 47 sheep in 2 trials. in the pilot trial no cerebral coenuri were found in 3 sheep which were treated with osa 28 and 14 days before challenge with 6 000 eggs of t. multiceps. cerebral coenuri were present in 3 untreated controls. in the second experiment 30 sheep were similarly treated with osa and challenged with 5 000 eggs of t. multiceps, while 11 sheep served a ...19827175904
observations on the course of taenia multiceps infections in sheep: clinical signs and post-mortem findings. 19827150943
treatment of the larval stage of taenia multiceps with praziquantel.five sheep were infested orally with 5,500 eggs of taenia multiceps and were treated with praziquantel (droncit, bayer) when they showed typical nervous signs of coenuriasis. two sheep were treated with praziquantel at 100 mg/kg live mass per day for 5 days, 2 sheep at the same dosage for 2 days and one animal at 50 mg/kg per day for 5 days. no viable coenuri were recovered from any of these animals. this is the only anthelmintic that is known to be effective against this parasite, but its cost ...19827120267
isolation of two lipoprotein antigens from the metacestodes of taenia hydatigena (pallas, 1766) and taenia multiceps (leske, 1780) and their evaluation in sero-diagnosis.two identical host contaminant-free lipoprotein antigens were isolated from the metacestodes of t. hydatigena and t. multiceps, of which antigen 1 was more reactive than antigen 2. these antigens appear to be identical with antigens b and a, respectively, and antigen 2 with arc 5 of echinococcus granulosus described by other workers. attempts to use these antigens in serodiagnosis showed that only in the indirect haemagglutination (iha) technique was there any increased sensitivity and specifici ...19826819681
investigation of effects of some immunoadjuvants and routes of antigen administration in raising antibodies in rabbits against metacestode cyst antigens of taenia multiceps.the relative efficiency of depot (freund's complete adjuvant (fca) and saponin), and non-depot (corynebacterium parvum strain p. acnes i, c. parvum strain imi585, and levamisole) immunoadjuvants were compared in raising agglutinating and precipitating antibodies against the metacestode fluid of taenia multiceps of sheep origin (tmcf). haemagglutinating but not precipitating antibodies were detectable during the period of primary immunisation. precipitating antibodies of higher titre were produce ...19836875260
some factors affecting the eggs of taenia multiceps: their transmission onto pasture and their viability. 19846541465
some host factors which influence the epidemiology of taenia multiceps infections in sheep. 19846486930
[a case of the acinous form of meningeal cysticercosis].a case of chronic cerebrospinal meningitis is described which caused considerable diagnostic difficulties. postmortem examination demonstrated parasitic character of the disease. although all cysts were sterile, the authors suggest in the discussion that in the case the cause was infestation with the larval from of the canine tapeworm taenia multiceps.19846483082
[biological cycle of multiceps multiceps isolated from man in the larval stage]. 19854040206
a method for estimating the age of coenuri of taenia multiceps recovered from the brains of sheep.the age of coenurus metacestodes from the brains of sheep has been estimated by counting the average number of scolices in each cluster on the coenurus wall and relating it to a calculated regression line derived from an examination of cysts of known age. the method has been applied to 17 natural infections and its value is discussed.19873672828
occurrence and biochemical characteristics of cestode lymphocyte mitogens.the cestodes echinococcus granulosus, taenia multiceps, t. pisiformis, t. hydatigena, hymenolepis diminuta, moniezia expansa and anoplocephala perfoliata all produced substances that stimulated thymidine incorporation by whole blood lymphocyte cultures. this mitogenic activity was demonstrated in metacestode cyst fluids, live protoscoleces and scoleces, parasite culture supernatants, and extracts of adult parasites. t. multiceps metacestode cyst fluid mitogen adhered to, but would not pass throu ...19873822512
immunization of sheep against the larval stage of taenia multiceps.a trial with 200 ewes and 127 lambs showed that vaccination of lambs with 2 doses of oncosphere secretory antigen (osa) 4 weeks apart, at either 4-8 and 8-12 weeks or at 12-16 and 16-20 weeks of age, was equally effective in protecting them against infestation with the larval stage of taenia multiceps. in this trial, the lambs of ewes, vaccinated with osa when they were 90 and again 120 days pregnant, were as susceptible to infestation as the lambs of untreated control ewes. another trial to pro ...19873306549
long-term follow-up of the surgical treatment of intracranial coenurosis.intracranial infestation by the coenurus of the tapeworm taenia multiceps is a rare occurrence in humans, with about 55 cases having been reported so far. although most of these cases were observed in african or south american countries, the illness was occassionally found also in sheep-raising areas of western europe and the united states. out of 4 personal cases, who were operated upon over an 18-year-period, 2 were neurologically intact respectively 20 and 3 years following surgical treatment ...19902334526
lymphoreticular responses to metacestodes: taenia multiceps (cestoda) can modify interaction between accessory cells and responder cells during lymphocyte activation.this study was designed to test the accessory function of macrophages after activation with products of taenia multiceps coenuri. activation was carried out by intraperitoneal injection of mice with coenurus fluid or protoscolex culture supernatant, and function was assessed by adding these macrophages in progressively increasing numbers to macrophage-depleted lymphocyte cultures transforming under the influence of plant mitogens or coenurus-fluid mitogen. in contrast to normal macrophages, whic ...19912038498
modification of cellular immunity by taenia multiceps (cestoda): accessory macrophages and cd4+ lymphocytes are affected by two different coenurus factors.taenia multiceps coenurus fluid was analysed by fast protein liquid chromatography in order to separate the factors responsible for previously reported modification of immunological activity in macrophages and t-cells. one factor, f7, was found to be mitogenic for murine l3t4+ t-cells, to be macrophage dependent, to require macrophage compatibility at the i region of the h2 complex, to increase the sensitivity of t-cells to regulatory signals from macrophages and to increase the rate of generati ...19911682871
[peritoneal infestation by tenia multiceps multiceps. an exceptional case of obstructive jaundice].the authors report an extraordinary case of obstructive icterus by endoperitoneal multiceps multiceps tenia cyst compressing bile ducts. the authors dwell upon the parasite's behaving the uncommon localization.19921529143
[the helminth fauna of red foxes (vulpes vulpes linnaeus 1758) in north hesse and east westphalia. 1. cestodes].between november 1989 and june 1990 a total number of 397 foxes were examined for the presence of cestodes. the animals came from the districts of arnsberg, detmold and kassel. in 16.4% of the foxes infections with echinococcus multilocularis were found, in 28.5% taenia crassiceps, in 14.4% taenia polyacantha, in 4.3% mesocestoides spp., in 3.3% multiceps multiceps, in 2.5% hydatigera taeniaeformis, in 0.8% taenia hydatigena and in 0.3% taenia martis. infections with echinococcus multilocularis ...19921396164
modification of accessory activity of sheep monocytes in vitro by a coenurus antigen from taenia multiceps.a factor in taenia multiceps coenurus fluid (tmcf) has previously been shown to modify the accessory activity of murine macrophages in vivo and in vitro. the factor (tmcf-f24) has been purified by ion exchange in a fast protein liquid chromatography (fplc) system. this study was conducted to determine whether tmcf-f24 is an antigen in naturally occurring cerebral coenuriasis, and whether it can also modify normal sheep blood monocytes. specific igg antibodies to tmcf-f24 were detected, using eli ...19921595191
metacestodes of sheep with special reference to their epidemiological status, pathogenesis and economic implications in fars province, iran.this study was undertaken over a period of 2 years. of 7992 sheep examined, 2088 (26.12%), 2266 (28.36%), 15 (0.19%) and 738 (9.8%) were infected with echinococcus granulosus, taenia hydatigena, taenia ovis and taenia multiceps metacestodes, respectively. the prevalence was higher in animals belonging to migratory tribal people than in those owned by the permanent residents of fars province. dogs in the former group also showed significantly higher levels of infection with e. granulosus (33.3%) ...19948171825
taenia multiceps (cestoda): ia antigen expression and prostaglandin secretion by parasite-modified, murine peritoneal macrophages.taenia multiceps secretions modify accessory cell activity in macrophages. the present experiments were designed to elucidate the cellular mechanisms involved. while normal, murine peritoneal macrophages amplified mitogen-activated t-cell proliferation, macrophages modified by exposure to parasite secretions inhibited this proliferation. the modified behaviour was shown by glutaraldehyde-fixed as well as living macrophages, and modification was inducible by fplc fraction 24 of coenurus fluid and ...19968758551
immunological activities of a lymphocyte mitogen isolated from coenurus fluid of taenia multiceps (cestoda).the purification of a mitogen from taenia multiceps coenurus fluid has been previously reported. in the present study, this activity, which was independent of endotoxin, stimulated the expression of lymphocyte il-2 and fc receptors, enhanced mitotic response to phylohaemogglutinin and concanavalin a and antagonised the previously described suppressive effects of the macrophage modifying fraction of coenurus fluid. the mitogen also increased peritoneal macrophage count and viability, fc receptor ...19979208030
human coenurosis in north america: case reports and review.coenurosis is a zoonotic disease of humans caused by the larval stage of taenia (multiceps) species. in north america, the adult tapeworm of taenia (multiceps) serialis is found in canids. the cystic larval forms (coenuri) are found in hares, rabbits, squirrels, and, rarely, in humans. we review in clinical detail the fifth case reported from north america, involving a child with extensive central nervous system involvement. we also report a sixth case, involving an adult with an intramuscular c ...19989770151
coenurus cerebralis infection in ethiopian highland sheep: incidence and observations on pathogenesis and clinical signs.an investigation was carried out at debre berhan, ethiopia, between 1996 and 1997, into the epidemiology of coenurosis in menz and horro breeds of sheep. a total of 37 heads from clinically sick and 183 heads from apparently healthy sheep were examined post mortem for the presence of the cystic larvae of taenia multiceps, of which 37 and 5 heads, respectively, contained 1 to 8 coenurus cysts (diameter 0.8 to 6.5 cm). the bladder worms were located in the cerebral hemisphere in 96% of the cases ( ...199910399813
nadh dehydrogenase subunit 1 and cytochrome c oxidase subunit i sequences compared for members of the genus taenia (cestoda).nine members of the genus taenia (taenia taeniaeformis, taenia hydatigena, taenia pisiformis, taenia ovis, taenia multiceps, taenia serialis, taenia saginata, taenia solium and the asian taenia) were characterised by their mitochondrial nadh dehydrogenase subunit 1 gene sequences and their genetic relationships were compared with those derived from the cytochrome c oxidase subunit 1 sequence data. the extent of inter-taxon sequence difference in nadh dehydrogenase subunit 1 (approximately 5.9-30 ...199910961852
effect of short-term coyote removal on populations of coyote helminths.coyote (canis latrans) removal programs often are initiated despite the potential population regulatory mechanism of parasitism with increased coyote density. we investigated the effect of intensive, short-term coyote removal on population levels of helminths in juvenile and adult coyotes from western texas. coyotes were killed by aerial gunning every 3 mo for 2 yr on two 5,000 ha areas, which reduced the overall coyote density of these areas by about 50%. two other 5,000 ha areas were used as c ...200211838229
prevalence of taenia multiceps in sheep in northern jordan.from march 1996 to february 1997, slaughtered-sheeps' heads were examined for the metacestode of taenia multiceps. out of 451 sheep heads, only 12 (3%) were infested. all cysts but one were in the age group 0.5-2.5 years old, with prevalence of 10% (11 of 108). eleven of 12 infested heads were found during the spring and autumn seasons. out of 95 flocks involved in questionnaire survey unrelated to the abattoir survey, all the farmers reported the existence of the clinical signs known for coenur ...200212383656
ecological analyses of the intestinal helminth communities of the wolf, canis lupus, in spain.this work describes the ecological characteristics of the intestinal helminth communities of 50 wolves (canis lupus l.) from spain. the species found were classified into three groups according to prevalence, intensity and intestinal distribution. taenia hydatigena pallas, 1766 and uncinaria stenocephala (railliet, 1884) are the core species of the community. taenia multiceps (leske, 1780) is a secondary species. the rest of the species, alaria alata (goeze, 1782), taenia serialis (gervais, 1847 ...200314535350
[a case of cerebral coenurosis].in this article the authors describe a case of cerebral coenurosis, a rare infection caused by the larval stage of the tapeworm taenia multiceps, encountered during their professional practice. the specific epidemiological elements, linked to the parasitic lifecycle in dogs, will also be covered. the authors consider the diagnostic, pathologic and clinical elements that allow differential diagnosis with respect to neurocysticercosis, a parasitic infection caused by the larval form of other cesto ...200415711135
clinicopathologic observations on coenurus cerebralis in naturally infected sheep.twelve sheep from 7 different flocks consisting of approximately 150-250 animals each were diagnosed with coenurosis caused by the larval stage of taenia multiceps. ataxia, incoordination, drowsiness, hind leg paralysis and coma were the most prominent clinical symptoms. monocytosis and lymphocytosis were observed upon hematological examination. creatin kinase (ckbb) levels of the animals varied between 421 and 495 u/l. cysts were commonly localized in the parietal and frontal lobes of the brain ...200515801624
genetic variation within taenia multiceps in sardinia, western mediterranean (italy).investigations were undertaken on taenia multiceps to determine if genetic variation was present within the parasites of sardinia (italy). forty samples were obtained from various locations of sardinia and deoxyribonucleic acid (dna) was extracted. polymerase chain reaction (pcr) was performed on nadh dehydrogenase i (nd1) and cytochrome c subunit 1 (co1) mitochondrial genes and amplicons were then sequenced and aligned with bioedit software. pairwise comparison between the nd1 sequences of the ...200616614827
helminthologic survey of the wolf (canis lupus) in estonia, with an emphasis on echinococcus granulosus.carcasses of 26 wolves were collected during the 2000/2001 and 2003/2004 hunting seasons and examined for helminths. thirteen helminth species were recorded: one trematode (alaria alata), seven cestodes (diphyllobothrium latum, mesocestoides lineatus, taenia hydatigena, taenia multiceps, taenia ovis, taenia pisiformis, and echinococcus granulosus), and five nematode species (uncinaria stenocephala, toxascaris leonina, toxocara canis, trichinella nativa, and trichinella britovi). the most common ...200616870858
updates on morphobiology, epidemiology and molecular characterization of coenurosis in sheep.taenia multiceps (leske, 1780) is a taeniid cestode that in its adult stage lives in the small intestine of dogs and other canids. the metacestode, previously known as coenurus cerebralis, is usually found in the nervous system including brain and spinal cord in sheep and other ruminants. the presence of cysts typically leads to neurological symptoms that in the majority of cases result in the death of the animal from starvation after some weeks. coenurosis could cause high losses in sheep farms ...200616881398
a study on intestinal helminthes of dogs, foxes and jackals in the western part of iran.human infection especially with helminth parasites is an emerging health issue, as the human environment is increasingly shared with infected animals, either pets or wild life. in this survey, the intestinal content of 83 stray dogs, 22 red foxes and 10 golden jackals collected from the west azarbaijan, kordestan and kermanshah provinces in the west of iran, were studied for the presence of helminth parasites. the percentage of different species recovered from these animals is listed as follows: ...200616899340
[imported coenurosis in sheep].thirteen sheep from a milk producing farm in the canton of grisons that presented chronic coenurosis were examined and subjected to treatment trials at the veterinary hospital in zurich. symptoms were first observed around two months after the import of two dogs from italy (abruzza) of which one was infected with taenia multiceps and echinococcus granulosus. the most frequently observed clinical symptoms of the sheep were reduced general condition, circling, reduced menace reflex, apathy, unstea ...200617024978
a survey of taenia multiceps coenurosis in sardinian sheep.a survey was carried out to assess the occurrence of coenurus cerebralis infection in sardinian sheep. a prevalence of 0.35% was observed when 566 regularly slaughtered sheep were examined. however, in 120 sheep with suspected symptoms of coenurosis examined from november 2001 to october 2002, a total of 299 cerebral coenurosis lesions were observed with an incidence of 1% per year. lesions were classified as migratory, cystic and secondary. most migratory lesions were found in sheep aged 3-6 mo ...200716973285
huge hemispheric intraparenchymal cyst caused by taenia multiceps in a child. case report.the authors report an unusual case of a huge intraparenchymal cyst in a 4-year-old girl caused by taenia multiceps infection. after surgical removal of the cyst, the child recovered completely. brain infestation by coenurus is a rare disease, mainly reported in africa, with a few case reports from patients in developed countries. humans, especially young children, become intermediate hosts by ingesting eggs passed in the excrement of a definitive host, usually carnivores. in such cases, high mor ...200718154024
vaccination with recombinant oncosphere antigens reduces the susceptibility of sheep to infection with taenia multiceps.taenia multiceps is a cestode parasite, the larval stage of which encysts in the brain of sheep, goats and cattle causing an often fatal condition. the parasite also causes zoonotic infections in humans. homologues of the recombinant oncosphere vaccine antigens from taenia ovis and other taenia species were identified in t. multiceps. sequencing of the associated t. multiceps genes and cloning of the encoding mrna has revealed conserved features in the genes and proteins. the t. multiceps oncosp ...200818160069
epidemiology and control prospects of foodborne parasitic zoonoses in the european union.in the 27 member states of the european union, zoonotic parasites transmitted by food are circulating with different prevalence according to the country, the environmental conditions, the human behaviour, and the socio-economic level. foodborne parasites can be divided in two main groups according to the way of transmission to humans. these foodborne parasites reach the human beings through the consumption of raw infected food such as muscle tissues of different animal species (toxoplasma gondii ...200818693552
taenia multiceps: a rare human cestode infection in israel.brain infestation caused by the metacestode of taenia multiceps is a rare phenomenon in humans, but is fairly common among sheep in mediterranean countries. no more than 150 human cases have been reported. in this present study, we report an unusual case of a huge intra-parenchymal cyst in a four-year-old girl caused by t. multiceps. no cross-reactivity between echinococcus granulosus and t. multiceps antigens was demonstrated. after surgical removal of the cyst, followed by chemotherapeutic tre ...200820411489
echinococcus granulosus and other intestinal helminths in semi-stray dogs in tunisia: infection and re-infection rates.assessing the baseline prevalence and the re-infection rate of e. granulosus and other cestodes in dogs is important for a control program based on regular dog dosing treatment with praziquantel mainly to young rural dogs.200819472727
[immune protection of recombinant membrane protein against taenia multiceps larvae in sheep].to investigate the immune protection of the recombinant membrane protein(45m) against larvae of taenia multiceps in sheep.200920066992
preliminary field trial of a vaccine against coenurosis caused by taenia multiceps.taenia multiceps is a taeniid cestode that in its adult stage lives in the small intestine of dogs and other canids. in the intermediate hosts, the larval stage of t. multiceps causes coenurosis, a common disease in the cns of ruminants, which typically leads to the death of the infected animals. recent research into new methods for control of coenurosis and other taeniid cestode infections such as hydatidosis has identified vaccination as a potentially valuable new tool. in order to test the ap ...200919345506
helminth parasites of the wolf canis lupus from latvia.thirty-four wolves were collected between 2003 and 2008 from throughout latvia and examined for helminths. a total of 17 helminth species were recorded: the trematode alaria alata (85.3%); the cestodes diphyllobothrium latum (2.9%), echinococcus granulosus (2.9%), echinococcus multilocularis (5.9%), mesocestoides lineatus (5.9%), taenia crassiceps (8.8%), taenia hydatigena (41.2%), taenia (ovis) krabbei (8.8%), taenia multiceps (47.1%), taenia pisiformis (20.6%), taenia polyacantha (11.8%), taen ...200919138449
pathological, molecular, and biochemical characterization of coenurus gaigeri in iranian native goats.coenurus gaigeri is the larval stage of taenia multiceps gaigeri, which infects the muscles of goats and, to a lesser extent, sheep. metacestodes of the goat such as coenurus cerebralis, cysticercus tenuicollis, cysticercus ovis, and hydatid cysts have been extensively studied. however, because of the uncommon occurrence of c. gaigeri, very few records exist of its biology, pathogenesis, and pathology. therefore, an investigation was conducted in the summer of 2008 at shiraz slaughterhouse, wher ...201020469949
non-cerebral coenurosis in goats.three hundred carcasses of young goats aged between 3 and 6 months were found to be infested with cysts at routine meat inspection at an abattoir in dubai in 2008. two types of cestode larvae were situated in the liver, abdominal cavities, under the skin and between the fasciae of the skeletal muscles. sixty-two typical coenuri loaded with multiple scolices (between 46 and 474) and situated in clusters (between 6 and 17) at the inner membrane of the bladder were recorded in numbers between one a ...201020502917
complete mitochondrial genomes of taenia multiceps, t. hydatigena and t. pisiformis: additional molecular markers for a tapeworm genus of human and animal health significance.mitochondrial genomes provide a rich source of molecular variation of proven and widespread utility in molecular ecology, population genetics and evolutionary biology. the tapeworm genus taenia includes a diversity of tapeworm parasites of significant human and veterinary importance. here we add complete sequences of the mt genomes of t. multiceps, t. hydatigena and t. pisiformis, to a data set of 4 published mtdnas in the same genus. seven complete mt genomes of taenia species are used to compa ...201020649981
the complete mitochondrial genomes of three cestode species of taenia infecting animals and humans.mitochondrial (mt) genome sequences provide useful markers for investigating population genetic structures, systematics and phylogenetics of organisms. although taenia multiceps, t. hydatigena, and t. taeniaeformis are common taeniid tapeworms of ruminants, pigs, dogs, or cats, causing significant economic losses, no published study on their mt genomes is available. the complete mt genomes of t. multiceps, t. hydatigena, and t. taeniaeformis were amplified in two overlapping fragments and then s ...201020922482
prevalence and molecular characterization of bovine coenurosis from eastern anatolian region of turkey.this study was conducted to determine the prevalence and molecular characteristics of coenurus cerebralis, the metacestode of taenia multiceps in cattle from erzurum province located in eastern region of turkey between november 2009 and april 2010. five of 1045 brains of cattle (0.47%) were found to be infected with coenurus cysts. the characteristics and morphology of c. cerebralis were seen in all the cysts. the cyts from three infected cattle were genetically analyzed and confirmed to be t. m ...201021074326
helminth infections of stray dogs from garmsar, semnan province, central iran.the aim was to study the gastro-intestinal helminths of stray dogs of garmsar, semnan province, central iran, and its impacts on human health and animal production.201022347264
first report of coenurosis in sheep in the state of mato grosso do sul, brazil.this paper reports the first case of coenurosis in the state of mato grosso do sul, brazil. this disease is caused by the larval stage of the tapeworm taenia multiceps (leske, 1780). the animal in which the disease was diagnosed was an 18-month-old ewe from an endemic area of southern brazil as an imported animal among a group of 30 sheep. the clinic-pathological condition was that commonly found in herbivores affected by the disease, especially sheep. apathy, nystagmus, intermittent blindness, ...201021184708
strategies for optimal expression of vaccine antigens from taeniid cestode parasites in escherichia coli.investigations were undertaken into optimizing the expression of cestode parasite vaccine antigens in the bacterium, escherichia coli to levels sufficient for mass production. a strategy to genetically engineer the antigens and improve their expression in e. coli was investigated. plasmid constructs encoding truncated parasite antigens were prepared, leading to removal of n and c-terminal hydrophobic domains of the antigens. this approach was found to be an effective strategy for improving expre ...201121222242
sequence variability in two mitochondrial dna regions and internal transcribed spacer among three cestodes infecting animals and humans from china.sequence variability in two mitochondrial dna (mtdna) regions, namely cytochrome c oxidase subunit 1 (cox1) and nadh dehydrogenase subunit 4 (nad4), and internal transcribed spacer (its) of rdna among and within three cestodes, spirometra erinaceieuropaei, taenia multiceps and taenia hydatigena, from different geographical origins in china was examined. a portion of the cox1 (pcox1), nad4 genes (pnad4) and the its (its1+5.8s rdna+its2) were amplified separately from individual cestodes by polyme ...201121745429
[cloning and sequence analysis of thioredoxin peroxidase gene from taenia multiceps].protoscoleces of taenia multiceps were collected from the naturally infected sheep and total rna was extracted. specific primers were designed according to tahe2-d11 mrna sequence and t. multiceps thioredoxin peroxidase gene (tmtpx) was amplified by rt-pcr. pcr products were ligated into pmd18-t vector and transformed to e. coli dh5alpha. the recombinant plasmids were identified by restriction digestion and sequencing. a 614 bp cdna was amplified. the tmtpx open reading frame (591 bp) encoded a ...201121823330
MRS Findings in Cerebral Coenurosis due to Taenia Multiceps.Cerebral coenurosis due to Taenia multiceps is a rare infection with no case reports from India. A 55-year-old male patient had presented with progressive symptoms of hemiparesis of 1-year duration. Magnetic resonance imaging (MRI) with magnetic resonance spectroscopy (MRS) of the lesion was performed that showed a septated cystic lesion in left parieto-occipital lobe. Multivoxel MRS through the lesion was performed using repetition time of 1500 ms and time to echo of 144 ms at 3T MRI. MRS showe ...201121699611
Genetic variation of the 8-kDa glycoprotein family from Echinococcus granulosus, Taenia multiceps and Taenia hydatigena.Echinococcosis, coenurosis and cysticercosis are debilitating diseases which prevail in China. Immunological diagnosis of metacestodosis is important in disease control. The 8-kDa glycoproteins from taeniid cestodes have successfully been used for diagnosis of human cysticercosis in immunological assays. The aim of the present study was to investigate genetic variations and phylogenetic relationships of the 8-kDa proteins for evaluating the possibility of utilizing these proteins as diagnostic a ...201122040491
survey on coenurosis in sheep and goats in egypt.a total of 75 sheep and goats from apparently healthy and from clinically affected flocks were examined for coenurus cerebralis cysts from different localities in egypt. of 25 animals examined from clinically diseased sheep and goats, 25 (100%) revealed the presence of infestation with one to four coenuri in the brain. the sites of predilection were the left hemisphere (48%), followed by the right hemisphere (40%) and the cerebellum (12%). there was no apparent effect of the age of sheep and goa ...201121947971
Coprological survey of alimentary tract parasites in dogs from Zambia and evaluation of a coproantigen assay for canine echinococcosis.Faecal samples were collected from the rectum of 540 domestic dogs from four districts (Lusaka, Katete, Petauke and Luangwa) in Zambia between 2005 and 2006 and prevalences of canine alimentary tract parasites were determined by coprological examination. Thirteen different ova and parasites including strongyle (43·3%), Spirocerca lupi (18·7%), taeniid (13·1%), Toxocara canis (7·6%), Sarcocystis sp.* (7·5%), Isospora sp.* (5·7%), Physaloptera sp.* (4·6%), Capillaria sp.* (2·8%), Dipylidium cani ...201122185947
cerebral coenurosis mimicking hydatid disease - report of two cases from south india.coenurosis, a rare zoonotic disease caused by the larval form of taenia multiceps (bladderworm) is common in sheep rearing countries, but human infections are rare. central nervous system involvement produces large giant sized cysts that radiologically closely mimic hydatid cysts. most human infections resulting in cerebral coenuri have been reported from europe and africa. we report two cases of cerebral coenurosis from india, the first in a 55-year-old male presenting with a large cystic lesio ...201121176715
detailed transcriptome description of the neglected cestode taenia multiceps.the larval stage of taenia multiceps, a global cestode, encysts in the central nervous system (cns) of sheep and other livestock. this frequently leads to their death and huge socioeconomic losses, especially in developing countries. this parasite can also cause zoonotic infections in humans, but has been largely neglected due to a lack of diagnostic techniques and studies. recent developments in next-generation sequencing provide an opportunity to explore the transcriptome of t. multiceps.201223049872
prevalence, predilection sites and pathological findings of taenia multiceps coenuri in slaughtered goats from south-east iran.coenurosis is a zoonotic disease in a variety of ruminants caused by the metacestode of taenia multiceps. the coenuri in the brain and spinal cord of sheep and goats have been identified as coenurus cerebralis whilst those reported in other tissues have been named coenurus gaigeri. this study was conducted during the spring and summer of 2011. out of 25 739 goats inspected in slaughterhouses, 23 carcasses (0.09%) revealed one or multiple visible swellings on the different muscles and visceral or ...201223327321
morphological and molecular characterization of bovine coenurosis in sardinia, italy.coenurosis is a central nervous system disease of wild and domestic ruminants caused by coenurus cerebralis, a bladder worm stage of taenia multiceps). even in sardinia island, this metacestode seems to be widespread in sheep (scala et al. vet parasitol 143(3-4):294-298, 2007) where coenurosis is an important health problem (varcasia et al. parasitol res 99(5):622-626, 2006) the last and unique report of coenurosis in cattle was in 1990 (cubeddu et al. 1990). in the present paper, a case of bovi ...201223274489
magnetic resonance imaging of the brain and skull of sheep with cerebral coenurosis.to determine mri characteristics of the skulls and brains of sheep with chronic cerebral coenurosis (cc) caused by naturally acquired taenia multiceps infection.201223176417
molecular characterization of subcutaneous and muscular coenurosis of goats in united arab emirates.coenurosis is a parasitic disease caused by the larval stage of taenia multiceps, which affects various ruminants species, particularly sheep and goats, and occasionally humans. in this note, non-cerebral coenurosis in goats with the goal to compare morphological and biomolecular characteristics is focused in order to determine if the non-cerebral specimens should be considered a new specie or a strain of t. multiceps. three hundred goats slaughtered with macroscopic lesions due to the presence ...201222884911
diagnosis and treatment of coenurosis in sheep.coenurosis is a disease of the central nervous system in sheep, caused by coenurus cerebralis, the larval stage of taenia multiceps, a tapeworm, which infests the small intestine of carnivores. in 80-90% of cases, the cyst is located in one cerebral hemisphere, whilst in 5-10% of cases, it is localised in the cerebellum; rarely it involves two sites in the brain of the affected animal. listeriosis, louping-ill, sarcocystosis and polioencephalomalacia and brain abscessation should be considered w ...201222503036
what is your neurologic diagnosis? taenia multiceps brain cyst. 201222332620
morphometric analysis of larval rostellar hooks in taenia multiceps of sheep in iran and its association with mitochondrial gene variability.the purposes of the present study were morphometric characterization of rostellar hooks of taenia multiceps and to investigate the association of hook length variation and the variability within two mitochondrial genes of sheep isolates of the parasite.201325516739
cloning and characterization of the fatty acid-binding protein gene from the protoscolex of taenia multiceps.taenia multiceps (cestoda: taeniidae), a worldwide cestode parasite, is emerging as an important helminthic zoonosis due to serious or fatal central nervous system disease commonly known as coenurosis in domestic and wild ruminants including humans. herein, a fatty acid-binding protein (fabp) gene was identified from transcriptomic data in t. multiceps. this gene, which contains a complete coding sequence, was amplified by reverse-transcriptase polymerase chain reaction. the corresponding protei ...201323474657
identification of neglected cestode taenia multiceps micrornas by illumina sequencing and bioinformatic analysis.worldwide, but especially in developing countries, coenurosis of sheep and other livestock is caused by taenia multiceps larvae, and zoonotic infections occur in humans. infections frequently lead to host death, resulting in huge socioeconomic losses. micrornas (mirnas) have important roles in the post-transcriptional regulation of a large number of animal genes by imperfectly binding target mrnas. to date, there have been no reports of mirnas in t. multiceps.201323941076
cytochrome c oxidase subunit 1 and 12s ribosomal rna characterization of coenurus cerebralis from sheep in iran.taenia multiceps is a widely distributed zoonotic tapeworm of canids. the larval stage of the parasite (coenurus) occurs in sheep, goat and cattle and has been rarely reported from humans. this study investigated genetic variability of two mitochondrial genes in 102 isolates of t. multiceps. metacestodes were collected from brains and hearts of sheep in tehran and qom provinces of iran. dna of each isolate was extracted and used for pcr amplification of cytochrome c oxidase subunit i (co1) and 1 ...201323890823
survey on helminths in the small intestine of wild foxes in qinghai, china.the intestinal helminth fauna of tibetan sand foxes (vulpes ferrilata) and red foxes (vulpes vulpes) inhabiting in qinghai, china, was evaluated by conducting necropsy of hunted foxes and fecal egg examination of field-collected feces. in northeast and south qinghai, 36 foxes were necropsied, and the species of foxes and the parasites detected were identified by the dna barcoding. in 27 red foxes and 9 tibetan sand foxes examined, mesocestoides litteratus (total prevalence: 64%), toxascaris leon ...201323749034
the nuclear 18s ribosomal rna gene as a source of phylogenetic information in the genus taenia.most species of the genus taenia are of considerable medical and veterinary significance. in this study, complete nuclear 18s rrna gene sequences were obtained from seven members of genus taenia [taenia multiceps, taenia saginata, taenia asiatica, taenia solium, taenia pisiformis, taenia hydatigena, and taenia taeniaeformis] and a phylogeny inferred using these sequences. most of the variable sites fall within the variable regions, v1-v5. we show that sequences from the nuclear 18s ribosomal rna ...201323183704
other cestodes: sparganosis, coenurosis and taenia crassiceps cysticercosis.many cestodes are capable of invading the central nervous system (cns), and several are highly prevalent in the developing world. neurocysticercosis due to taenia solium and echinococcosis due to echinoccocus granulosus are two of the most common parasitic infections affecting humans, but other less well-known parasites can also infect the nervous system. coenurosis, caused by taenia spp. such as t. multiceps, t. serialis, or t. brauni; sparganosis, caused by spirometra spp., and neurocysticerco ...201323829923
molecular characterization of taenia multiceps isolates from gansu province, china by sequencing of mitochondrial cytochrome c oxidase subunit 1.a total of 16 taenia multiceps isolates collected from naturally infected sheep or goats in gansu province, china were characterized by sequences of mitochondrial cytochrome c oxidase subunit 1 (cox1) gene. the complete cox1 gene was amplified for individual t. multiceps isolates by pcr, ligated to pmd18t vector, and sequenced. sequence analysis indicated that out of 16 t. multiceps isolates 10 unique cox1 gene sequences of 1,623 bp were obtained with sequence variation of 0.12-0.68%. the result ...201323710087
efficacy of albendazole against taenia multiceps larvae in experimentally infected goats.a controlled trial was conducted to evaluate the efficacy of three therapeutics regimes of albendazole (abz) against taenia multiceps larvae in experimental infected goats. forty-nine goats experimentally infected with 3000 t. multiceps eggs were selected and randomly divided into treatment or control groups. treatment with 10mg/kg for 3 days for group 1 (g1), 10mg/kg for group 2 (g2) and 20mg/kg/day for group 3 (g3) was applied 2 months after infection; group 4 (g4) served as a control group. a ...201425450723
cerebral and non-cerebral coenurosis in small ruminants.cerebral coenurosis is caused by coenurus cerebralis, the larval stage of taenia multiceps. the metacestode causes severe lesions in the brain and spinal cord of the intermediate host, so-called "gid" or "stagger" disease. whereas, the non-cerebral coenurosis caused by coenurus gaigeri, the larval stage of taenia gaigeri, particularly affects goats. the cyst form of the taenia gaigeri is found in intramuscular and subcutaneous tissues. the difference in the sequence of mitochondrial genes of cox ...201424862039
cisternal cerebrospinal fluid analysis in 24 sheep with chronic coenurosis.coenurosis, a neurological parasitic infection of ruminants caused by the larval stage of taenia multiceps, is commonly reported in sardinia, the most representative region for ovine population in italy. chronic form appears as a consequence of cyst development, frequently reported in the brain and spinal cord. diagnostic suspect of coenurosis is based on physical and neurological examination. the aim of this article is to describe physical, biochemical and cytological aspects of cisternal cereb ...201424715594
taenia multiceps brain cyst removal in two wild nubian ibex (capra nubianas).two wild adult nubian ibex (capra nubiana) were captured and admitted to the hebrew university veterinary teaching hospital with various neurologic signs, including alerted mentation, head tilt, and pathologic nystagmus. the lesion in the central nervous system was localized to the forebrain in one ibex and to the cerebellum of the other. both ibex's were diagnosed with brain cyst using computed tomography (ct). craniectomy was performed to remove the cysts, and both animals returned to their na ...201424712185
expression, tissue localization and serodiagnostic potential of taenia multiceps acidic ribosomal protein p2.the larval stage of taenia multiceps, also known as coenurus, is the causative agent of coenurosis, which results in severe health problems in sheep, goats, cattle and other animals that negatively impact on animal husbandry. there is no reliable method to identify coenurus infected goats in the early period of infection.201526626136
[observation on the histologic structure of multiceps multiceps in artificially infected dogs].to observe the microstructure and ultrastructure of multiceps multiceps from the artificially infected dogs. metheds: two male dogs were infected with the coenurus of m. multiceps from naturally-infected sheep (about 80-100 per dog). the adult worms of m. multiceps were recovered from the intestine, and fixed by the conventional method. the scolex, neck, immature proglottid, mature proglottid, and gravid proglottid were prepared for paraffin section and ultrathin sections with he staining and ur ...201526541033
comparison of cerebral and non-cerebral coenurosis by genetic markers of glycolytic enzyme (enolase) and mitochondrial sequences in sheep and goats.coenurosis is a debilitating disease caused by the larval stage of taenia multiceps. the larval stage of t. multiceps appears in two cerebral and non-cerebral forms known as coenurus cerebralis and coenurus gaigeri,respectively. this leads to the hypothesis that there are genetic intraspecific variabilities within this species. molecular analysis in the present study showed that c. cerebralis and c. gaigeri were 100% genetically identical based on exonic region of enolase (eno) gene and both mit ...201526527237
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