Publications

clostridium hiranonis sp. nov., a human intestinal bacterium with bile acid 7alpha-dehydroxylating activity.	the clostridium-like organisms to-931t and hd-17, isolated from human faeces, have high levels of bile acid 7alpha-dehydroxylating activity. sequencing of their 16s rdna demonstrated that they belong to cluster xi of the genus clostridium and that they represent a new and distinct line of descent. clostridium bifermentans and clostridium sordellii in cluster xi also possess bile acid 7alpha-dehydroxylating activity. dna-dna hybridization experiments with the isolates, to-931t and hd-17, and c bi ...	2001	11211270
development and application of a polymerase chain reaction assay for the detection and enumeration of bile acid 7alpha-dehydroxylating bacteria in human feces.	secondary bile acids are synthesized in the human colon from the bacterial 7alpha-dehydroxylation of primary bile acids. increased levels of secondary bile acids have been correlated with an increased risk of colon cancer and cholesterol gallstone disease. based on 16s rdna sequence analysis, stock cultures of bacterial strains with bile acid 7alpha-dehydroxylation all belong to the genus clostridium.	2003	12691873
comparison between cultured small-intestinal and fecal microbiotas in beagle dogs.	the microbiota of the small intestine is poorly known because of difficulties in sampling. in this study, we examined whether the organisms cultured from the jejunum and feces resemble each other. small-intestinal fluid samples were collected from 22 beagle dogs with a permanent jejunal fistula in parallel with fecal samples. in addition, corresponding samples from seven of the dogs were collected during a 4-week period (days 4, 10, 14, and 28) to examine the stability of the microbiota. in the ...	2005	16085799
bacterial conversion of secoisolariciresinol and anhydrosecoisolariciresinol.	it has been investigated whether secoisolariciresinol (seco) and anhydrosecoisolariciresinol (ahs), an acid degradation product of seco, could be fermented in a similar way, and to a similar extent, by members of the intestinal microbiota.	2009	19302311
phylogenomic analysis of the family peptostreptococcaceae (clostridium cluster xi) and proposal for reclassification of clostridium litorale (fendrich et al. 1991) and eubacterium acidaminophilum (zindel et al. 1989) as peptoclostridium litorale gen. nov. comb. nov. and peptoclostridium acidaminophilum comb. nov.	in 1994, analyses of clostridial 16s rrna gene sequences led to the assignment of 18 species to clostridium cluster xi, separating them from clostridium sensu stricto (clostridium cluster i). subsequently, most cluster xi species have been assigned to the family peptostreptococcaceae with some species being reassigned to new genera. however, several misclassified clostridium species remained, creating a taxonomic conundrum and confusion regarding their status. here, we have re-examined the phylo ...	2016	27902180
effects of the dietary protein and carbohydrate ratio on gut microbiomes in dogs of different body conditions.	obesity has become a health epidemic in both humans and pets. a dysbiotic gut microbiota has been associated with obesity and other metabolic disorders. high-protein, low-carbohydrate (hplc) diets have been recommended for body weight loss, but little is known about their effects on the canine gut microbiome. sixty-three obese and lean labrador retrievers and beagles (mean age, 5.72 years) were fed a common baseline diet for 4 weeks in phase 1, followed by 4 weeks of a treatment diet, specifical ...	2017	28119466