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bioreactor studies on the endophytic fungus entrophospora infrequens for the production of an anticancer alkaloid camptothecin.twigs (young and old) from nothapodytes foetida growing in the jammu and mahabaleshwar regions in india were used for the isolation of 52 strains of endophytic fungi and were tested for their ability to produce the anticancer alkaloid camptothecin. one of the isolates from the inner bark tissue of the n. foetida plant growing in the jammu region of j&k state, india, was found to produce detectable quantities of camptothecin and its derivatives when grown in a semi-synthetic liquid medium. campto ...200616604115
immunomodulatory activity of an extract of the novel fungal endophyte entrophospora infrequens isolated from nothapodytes foetida (wight) sleumer.a novel camptothecin-producing endophytic fungus viz., entrophospora infrequens was isolated from an important indian medicinal plant nothapodytes foetida. the present study reports evaluation ofbioactivities of two novel extracts viz., chloroform (ceei) and methanolic (meei) extracts of entrophospora infrequens with respect to their immunomodulatory potential in vitro and in vivo (in balb/c mice). the endophyte e. infrequens was found to synthesize camptothecin, which tested positive in ceei. t ...200717896474
otospora bareai, a new fungal species in the glomeromycetes from a dolomitic shrub land in sierra de baza national park (granada, spain).a new fungal species of the glomeromycetes was isolated from the rhizosphere of pterocephalus spathulatus and thymus granatensis, two rare endemic plants growing on dolomite in the sierra de baza (granada, southern spain). the fungus was propagated in pot cultures of sorghum vulgare and trifolium pratense for 4 y and it is described here on the basis of the spores found in nature and formed in pot cultures. its brown spores (140-210 microm diam) form laterally on a persistent, brown stalk (=neck ...200818592903
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