Publications

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observations on pityrosporum ovale in seborrheic blepharitis and conjunctivitis. 194720273107
pityrosporum ovale; a cause of blepharitis. 195015422258
[cytological and bacteriological of conjunctival smears, pityrosporum ovale]. 195015419526
[culture of pityrosporum ovale on oleic acid medium]. 195114934185
[pityriasis versicolor and pityrosporum ovale]. 195213031305
experimental studies on pityrosporum ovale: its pathogenicity and antigenic capacity. 195212990836
[studies on pityrosporum ovale. i. pathogenic action]. 195212980574
pityrosporum ovale and some scaly conditions of the scalp. 195313009255
[studies on pityrosporum ovale. ii. antigenic capacity]. 195313060941
pityrosporum ovale types cultured from normal and seborrheic subjects. 195413137602
a note on the growth of malassezia furfur. 195813541320
[pityrosporum ovale as a cause of allergy to human scurf]. 195813592196
the activity of polymethylene-bis-4-amino-quinaldinium salts against pityrosporum ovale and candida albicans. 196113696141
[the morphology of malassezia furfur (robin) (baillon, 1889)]. 196214476221
etiological significance of pityrosporum orbiculare in tinea versicolor. 19635896183
the requirement of fatty acids by pityrosporum ovale. 196314053273
[can pityrosporum ovale cause a skin infection?]. 196414304655
an ultrastructure study of pityrosporum orbiculare. 196414220229
tissue culture technique for the subcultivation of pityrosporum ovale (wild strain). 19654953539
ultrastructure of pityrosporum ovale and pityrosporum canis. 19654160035
a simple medium for continuous subculture of pityrosporum orbiculare.a simple medium for continuous subculture of pityrosporum orbiculare is described and the advantages of this medium are briefly discussed.196625622351
electron microscopy of malassezia furfur in tinea versicolor. 19665977762
pityrosporum orbiculare. its possible role in seborrheic blepharitis. 19674225663
the sulphur metabolism of pityrosporum ovale and its inhibition by selenium compounds. 19675582657
lack of swelling and shrinking of pityrosporum ovale in media of different osmotic pressures and its relationship with survival in the relatively dry conditions of the scalp. 19676068443
relative effectiveness of different classes of fungicides against pityrosporum ovale. 19685748582
alkylaminoalkyl-dithiocarbamic acids, new drugs against pityrosporum ovale. 19684237099
a study of the fatty acid metabolism of the yeast pityrosporum ovale.the yeast pityrosporum ovale, a skin saprophyte, will only grow if fatty acids of chain length greater than c(10) are added to the culture medium. 9-hydroxypalmitic acid is the major product of metabolism of even-carbon-number fatty acids; 9-hydroxystearic acid is also found. the optimum ph for this conversion is ph4.5. the hydroxy fatty acids produced are found bound in a polar form in the aqueous phase of the culture medium. growth of the organisms is facilitated by presentation of the substra ...19685691082
[laboratory infection caused by malassezia furfur]. 19685761208
pityrosporum orbiculare: incidence and distribution on clinically normal skin. 19695813527
cultivation and pathogenicity of malassezia furfur with special respect to mycological studies on etiological fungus of tinea (pityriasis) versicolor. 19695382447
confluent and reticulate papillomatosis (gougerot-carteaud) and pityrosporum orbiculare. 19695391101
an electron microscope study of the yeast pityrosporum ovale. 19704192087
comedogenic potential of the lipid extract of pityrosporum ovale. 19704250567
composition of the cell wall of pityrosporum ovale (bizzozero) castellani and chalmers. 19705462975
[serologic differentiation between pityrosporum canis and pityrosporum ovale]. 19724508516
the ultrastructure of tinea versicolor and malassezia furfur. 19724554182
scanning electron microscopy of tinea versicolor organisms. (malassezia furfur--pityrosporon orbiculare?). 19734692129
[culturability of pityrosporum orbiculare on various culture media and resistance testing using various antimycotics]. 19734752505
[malassezia furfur in a case of generalized pityriasis versicolor]. 19744847381
cytopathology of nipple discharge due to pityrosporum orbiculare and cocci in an elderly woman.a case has been described where cytologic examination first showed a fungus infection as the possible cause of a nipple discharge of long duration. the discharge was found to be associated with pityrosporum orbiculare, micrococcus tetragenes and staphylococci (coagulase negative). administration of an antibiotic that inhibited the bacteria cured the condition.197546660
quantitative microbiology of the scalp in non-dandruff, dandruff, and seborrheic dermatitis.the composition of the scalp microflora was assessed quantitatively in normal individuals and in patients with dandruff and seborrheic dermatitis, disorders characterized by increasing scaling. three organisms were constantly found: (1) pityrosporum, (2) aerobic cocci, and (3) corynebacterium acnes. pityrosporum (mainly pityrosporum ovale) made up 46% of the total microflora in normals, 74% in dandruff, and 83% in seborvheic dermatitis. the geometric mean number of organisms per cm-2 in non-dand ...1975237965
miconazole: a review of its antifungal activity and therapeutic efficacy.miconazole2, a synthetic imidazole derivative, is a new topical antifungal agent for use in the local treatment of vaginal, and skin and nail infections due to yeasts and dermatophytes. it is particularly active against candida spp., trichophyton spp., epidermophyton spp., microsporum spp. and pityrosporon orbiculare (malassezia furfur), but also possesses some activity against gram-positive bacteria. in vaginal candidiasis, miconazole vaginal cream has produced higher cure rates than convention ...19751149649
[occurrence of pityrosporum ovale in the human ear (author's transl)]. 19751213229
ciclopirox: a new topical pyrodonium antimycotic agent. a double-blind study in superficial dermatomycoses.one percent ciclopirox solution, a new topical antimycotic agent, was used in a double-blind controlled trial in 105 dermatomycosis patients. twelve of the patients were lost to follow-up. of the remaining ninety-three patients, forty-four were treated with the active drug, forty-nine with a placebo. the cure rate amongst those using ciclopirox was significantly superior to that of the placebo. the drug was effective against trichophyton rubrum, t. violaceum, t. mentagrophytes and malassezia fur ...1976782504
clinical evaluation of clotrimazole. a broad-spectrum antifungal agent.the efficacy and safety of the broad-spectrum, topically applied antifungal agent clotrimazole were evaluated in two double-blind, multicentric trials. ten investigators reported on a total of 1,361 cases in which a 1% solution or a 1% cream formulation was compared with its respective vehicle. clotrimazole was therapeutically effective, as confirmed by mycological cure (negative microscopy and culture) and clinical improvement, in tinea pedis, tinea cruris, tinea corporis, pityriasis versicolor ...1976769697
growth requirements and lipid metabolism of pityrosporum orbiculare.the yeast, pityrosporum orbiculare, isolated from lesions from lesions of tinea versicolor, grows in vitro only if fatty acids from the c12 to c24 series are added to the culture medium. except for elaidinic and nervonic acids, all saturated and unsaturated fatty acids tested support growth. p. orbiculare can synthesize various lipid fractions containing both saturated and unsaturated fatty acids from a single fatty acid. glucose and asparagine stimulate growth but exogenous vitamins do not.19761249447
freeze-fracture replication of cultured pityrosporum orbiculare.skin scrapings from a patient with pityriasis versicolor were plated on a bile salt medium containing 10% glycerol (for cryoprotection) and pityrosporum orbiculare was harvested for freeze-fracture replication. resting and budding cells were senn. the overall pattern of indentation of the plasma membrane towards the cytoplasm was well revealed as a spiral arrangement of major indentations with minor ones disposed more or less at right angles. hexagonally-arranged particles were not observed. mit ...19761265568
[letter: pityrosporum ovale. fungistatic action of 2 antibiotics]. 19761264621
some aspects of the role of pityrosporum ovale in dandruff. 1976967913
treatment of pityriasis capitis (dandruff) with econazole nitrate.63 patients of both sexes with pityriasis sicca or steatoides were examined for presence of pityrosporum ovale on the scalp. only those cases in which very numerous yeasts were seen in all squamae present in the preparation were considered positive. according to the severity or duration of pityriasis, 60% of the patients in this population represented severe cases and 38% refractory cases. a solution of econazole nitrate was applied as a spray, morning and evening, for a period of 10 to 20 days ...197774174
[pityrosporum orbiculare in acneiform eruptions].six patients with acneiform eruptions in the predilection sites of pityriasis versicolor are briefly described. histologically there were abscesses below the acroinfundibulum wherein yeasts could be found with the characteristics of pityrosporum orbiculare. the possible pathogenity of these fungi is discussed.1977143463
pityrosporum species associated with dacryoliths in obstructive dacryocystitis.two dacryoliths removed from the obstructed and enlarged lacrimal sac of a 54-year-old woman during dacryocystorhinostomy were found to contain filamentous forms consistent with pityrosporum orbiculare. to my knowledge, this fungus has not been observed before in a dacryolith or in dacryocystitis.1977596394
induction of hyphae in cultures of pityrosporum by cholesterol and cholesterol esters.the effect of cholesterol and cholesterol esters on pityrosporum cultures has been studied. a mixture of 0.25% to 2.0% of cholesterol:cholesteryl stearate:glyceryl monostearate (2.0:1.5:2.0) added to bacto yeast morphology agar plus oleic acid was able to induce hyphae in cultures of both pityrosporum orbiculare and p. ovale. this result is discussed with respect to the cholesterol effect on cell membranes and to the occurrence of cholesterol and cholesterol esters in the scaling patches of pity ...1977925376
the effect of topical retinoic acid (airol) in the treatment of tinea versicolor.a clinical trial with retinoic acid (airol) cream 0.05% applied topically was carried out on 50 patients suffering from tinea versicolor allocated to a random procedure. the results, judged in terms of cure rate, incidence of relapse and tolerance were very satisfactory. as regards the above mentioned criteria for a successful treatment, there was no significant difference between the lotion and cream groups. repigmentation of the affected skin after retinoic acid occurred in a relatively shorte ...1977888002
dimorphism of pityrosporum orbiculare in a defined culture medium.dimorphism of pityrosporum orbiculare was induced in an artificial culture medium which consisted of 0.05 m glycine in 0.03-0.06 m ammonium phosphate buffer (ph 5.6), salts, glucose, and tween-80. of the strains tested, 78 to 85% produced hyphal elements from up to 8.5% of yeast cells. morphologic features of p. orbiculare in culture were examined by scanning electron microscopy and compared with the appearance of fungus from clinical lesions of tinea versicolor. morphologically, the fungi obtai ...1977881572
polymorphism of malassezia furfur.alterations in the morphologic and physiologic characters of 11 isolates of pityrosporum orbiculare were noted upon prolonged maintenance in pure culture. successive subculturing of each isolate resulted in its progressive conversion from globose (p. orbiculare) through ovoid to cylindrical (p. ovale) form. globose forms utilized neither olive oil nor tween 20 as a sole carbon source, nor kno3 as a sole source of nitrogen, while ovoid and cylindrical forms utilized both of these carbon sources, ...1977861851
in vitro and in vivo ultrastructural changes in pityrosporum orbiculare after treatment with econazole. 1978299492
morphological and cultural aspects of pityrosporum (malassezia) furfur. 1978299470
a reappraisal of the role of pityrosporum orbiculare in pityriasis versicolor and the significance of extracellular lipase.pityrosporum orbiculare is an obligate lipophilic yeast in vitro, which suggests it possesses an extracellular lipase crucial for nutrition. if present in vivo, the enzyme would enable the yeast to utilize skin surface lipids, which may therfore play an important role in the pathogenesis of pityriasis versicolor. cultured p. orbiculare and biopsy material from patients with pityriasis versicolor were investigated for the presence of lipase by electron microscope histochemistry. at sites of lipas ...1978722119
taxonomy of exophiala jeanselmei (langeron) mcginnis and padhye.the black yeast-like fungus exophiala jeanselmei (langeron) mcginnis et padhye was originally described as torula jeanselmei by langeron. since its original description in 1928, this dematiaceous hyphomycete has been placed in the genera phialophora, pullularia and rhinocladiella by various authors. study of the type culture of e. jeanselmei has confirmed that the principle conidiogenous cells of this fungus are annellides, thus supporting its current generic disposition. after reviewing the neo ...1978570642
the occurrence of simple and mixed fungal infections in patients at the department of andrology/hamburg (1972--1976).skin scales from 228 patients, referred to the department of andrology at the university of hamburg during 1972--76, were examined mycologically, because of being suspect of mycotic infections. in 54 cases dermatophytes were isolated, and yeasts were found in 13 cases. nocardia minutissima and malassezia furfur were present in 138 and 25 cases, respectively. in 12 patients, mixed infections were diagnosed; the infective organisms were yeasts in 46.2% of the cases, dermatophytes in 11.1%, and mal ...1978717818
ultrastructural basis for the assay of topical acne treatments. transmission and scanning electron microscopy of untreated comedones.after two decades of using systemic antibiotics as a main treatment for acne, emphasis is again being placed on topical agents. thus, it is highly desirable to have a procedure whereby the activity of the various compounds can be evaluated by direct visualization. scanning electron microscopy combined with transmission electron microscopy provide the tools for such in assay. this study describes the ultrastructure of untreated comedones and provides the baseline or control data necessary for tes ...1978151693
cell-mediated immunity to pityrosporum orbiculare in tinea versicolor.pityrosporum orbiculare, the presumed etiologic agent of tinea versicolor, was cultured in vitro and antigenic extracts prepared from the cultured organisms. studies with lymphocytes from human cord blood and peripheral blood of guinea pigs demonstrated that such extracts were not mitogenic. further studies in guinea pigs indicated that the animals could be sensitized by the injection of p. orbiculare extract in freund's complete adjuvant and that this extract could elicit lymphocyte transformat ...197896143
pityrosporum ovale and acne vulgaris. 1978162563
[saphrophytic life of opportunistic fungi].probably all pathogenic fungi can cause opportunistic infections in compromised hosts. this paper briefly reviews our knowledge on the saprophytic life - geographic distribution and habitat - of the most common pathogenic fungi. some mycoses are of endogenous origin - e.g. candida albicans is an endosaprophyte - others of epigenon origin - e.g. pityrosporum ovale is an episaprophyte - but most mycoses are caused by fungi which have an exosaprophytic (or exosaprobic) life: one becomes infected af ...1979114433
immunological studies on pityrosporum genus and malassezia furfur.the antigenicity of malassezia furfur from patients with tinea versicolor and 3 species of pityrosporum was investigated using the antiserum against p. orbiculare. the ouchterlony gel diffusion test revealed a considerable similarity between the antigenicities of p. orbiculare and p. ovale, and little similarity between p. orbiculare andp. canis. similar results were obtained by immunofluorescence staining with the fitc-labeled p. orbiculare antiserum. hyphae and round spores of m. furfur in the ...1979115927
confluent and reticulated papillomatosis (gougerot-carteaud).seven cases, one female and six males with confluent and reticulated papillomatosis are presented. age range was 13-25 years and the skin disease had lasted for 6 months to 3 years. initially, acanthosis nigricans was suspected in all cases as the skin histology was compatible with that diagnosis. pityrosporum orbiculare was cultured in 4 cases, but treatment with selenium sulfide and miconazole was unsuccessfull. no endocrinological abnormities were revealed. only associated feature was a marke ...1979294095
tinea versicolor and pityrosporum orbiculare: mycological investigations, experimental infections and epidemiological surveys.in patients with tinea versicolor, pityrosporum orbiculare was cultured from tinea versicolor lesions in 100%, from normal-looking skin in 80%, and from apparently healed lesions in 69%. p. orbiculare was isolated from normal skin in 85% of patients with seborrheic dermatitis and in 90% of volunteers. the best substrate for isolation of p. orbiculare was a peptone-glucose-yeast extract medium containing glycerol monostearate and tween 80, overlaid with olive oil. germ tubes were produced when p. ...1979390959
taxonomy of exophiala werneckii and its relationship to microsporum mansonii.study of the neotype culture of exophiala werneckii (cladosporium werneckii), as well as additional isolates, has shown that the yeast-like and hyphal conidiogenous cells are annellides. e. werneckii cannot be accommodated in cladosporium, a genus characterized by catenulate holoblastic coanidia. e. werneckii and the dematiaceous hyphomycete that castellani misidentified as microsporum mansonii (cladosporium mansonii) are two entirely different fungi. m. mansonii is considered to be a synonym of ...1979575579
experimental tinea versicolor in rabbits and humans with pityrosporum orbiculare.the purpose of this investigation was to produce experimental tinea versicolor in rabbits and humans with pityrosporum orbiculare. inoculation with p. orbiculare under plastic occlusion on the glabrous follicle-rich inside of the rabbit ear resulted in a tinea versicolor-like lesion after 1 week in 3 of 4 animals. one week after inoculation with p. orbiculare under plastic occlusion, experimental infections similar to those found clinically in tinea versicolor were seen in 10 of 12 patients with ...1979448167
superficial mycoses in a southern new zealand district.a total of 2,709 pathogenic fungi were isolated from 8,762 patients suspected as having mycotic disease, over an 8 year period in christchurch, new zealand. the district is climatically designated as temperate with average mean temperatures of 17 degrees c in summer and 8 degrees c in winter. the predominant species of fungi were relatively small in number with trichophyton mentagrophytes var. interdigitals as the major pathogen. fungi other than true dermatophytes, particularly candida spp. and ...1979396678
tinea versicolor and pityrosporum orbiculare: a mycological investigation. 1979161078
the activity in vitro of five different antimycotics against pityrosporum orbiculare.the activity in vitro of miconazole, clotrimazole, econazole, sodium omadine, and sodium thiosulphate against pityrosporum orbiculare was found to correlate with the good clinical results these drugs produce in tinea versicolor. in addition many substances used as solvents or in vehicles had an inhibitory effect in vitro against p. orbiculare. the influence of the culture medium, especially lipids, on the action of imidazole derivatives is discussed.197994211
tinea versicolor and body lotions.a woman complained she had caught her "white spots" from an american sun lotion. the daughter also had them. the mother's spots showed malassezia furfur. the daughter, by a curious coincidence, had developed vitiligo at the same time. as a comfort it was agreed that the sun lotion should be examined for fungal contamination. scrapings from lesions of patients with tinea versicolor show a typical appearance of malassezia furfur. roberts (9) cultured specimens from 27 patients and isolated pityspo ...19806162319
scanning electron microscopy of yeasts in seborrheic keratoses.lesions of seborrheic keratoses were studied by scanning electrom microscopy. numerous yeasts were present on the karatinized cells and hairs associated with the lesions. surfaces of some yeasts were smooth and others were ruffled. the ruffles suggested the presence of a glycocalyx. the yeasts exhibited the morphological features of pityrosporum ovale.19806444640
serologic analysis of the extractable carbohydrate antigens of pityrosporum ovale.antigens soluble in hot trichloracetic acid from eighteen strains of pityrosporum ovale were studied using rabbit antiserum to american type culture collection strains 24027, 12078, and 14521. these strains were found to share two antigens, both of which were present in cells of pityrosporum orbiculare and one of which was present in cells of pityrosporum pachydermatis, pityrosporum canus, candida albicans and rhodotorula rubrum.19806779094
activation of the alternative pathway of complement by malassezia ovalis (pityrosporum ovale).activation of c3 and factor b in normal human serum by p. ovale was demonstrated using a standard unidirectional immunoelectrophoresis technique. activation of complement by the alternative (properdin) pathway is a possible mechanism by which p. ovale may mediate an inflammatory response.19806900183
one case of confluent and reticulate papillomatosis (gougerot-carteaud).a 16-year-old girl with dark-brown coalescing papules symmetrically localized to the cheeks, is reported. the diagnosis may be consistent with the criteria for confluent and reticulate papillomatosis (gougerot-carteaud). the association between this disease and pityrosporum orbiculare is discussed.19806158235
age incidence of pityrosporum orbiculare on human skin.we have investigated the incidence of the lipophilic fungi pityrosporum orbiculare and p. ovale on clinically normal skin in newborn children and in children at the age of 6 months, 1 year, 5 years, 10 years, and 15 years. p. orbiculare was absent in children of less than 5 years of age. it was present in the highest incidence (93%) in the 15-year-old children, about the same frequency as in adults. the colonization starts during the period when the sebaceous glands become active. p. ovale could ...19806162342
the prevalence of yeasts in clinical specimens from cancer patients.yeasts recovered from cancer patients during a 15-month period were speciated, and the prevalence of these isolates in various types of clinical specimens was determined. five species, including candida albicans, candida tropicalis, candida parapsilosis, candida krusei, and torulopsis glabrata, accounted for 97.1% of the isolates. eighteen different species were recovered. respiratory and urine specimens yielded 75% of the organisms. c. albicans, c. tropicalis, and c. parapsilosis were recovered ...19807369176
[experimental dermatitis caused by pityrosporum ovale and (or) pityrosporum orbiculare in the guinea pig and the mouse].an experimental dermatitis was established for the guinea pig and swiss white mouse by topical application of cultures of pityrosporum ovale, isolated from pityriasis capitis and from p. arbiculare isolated from pityriasis versicolor. histology showed the development of the yeasts in the stratum corneum, with hyperkeratosis at the follicular ostium and in the pilous bulb: the clinical and histological appearances resembled human seborrheic dermatitis. the nude (nu/nu) mouse, the hair-less mouse ...19807423333
treatment of pityriasis versicolor with ketoconazole.eighty-two patients with pityriasis versicolor were treated orally with ketoconazole in tablet form (200 mg). the tablets were taken at least 90 min before a meal, and patients who received only one tablet daily were told to refrain from bathing except immediately before ingestion of the drug and only once a day. dosage of ketoconazole varied from a single dose of 400 mg to 200--400 mg per day for four weeks. seventy-seven patients reported no adverse effects. there were reports from others of h ...19806255536
comparison of antibody responses in chronic mucocutaneous candidiasis and tinea versicolor.antibody titers against candida albicans and pityrosporum orbiculare, the presumed etiologic agent of tinea versicolor, were determined in normal subjects, and in patients with tinea versicolor or chronic mucocutaneous candidiasis. whereas antibody against both organisms was found in low titer in normal subjects, a majority of patients with each infection had elevated antibody titers against the infecting organism. patients infected with one organism did not have elevated titers against the othe ...19806995349
antimycotic activity of propane-1,2-diol (propylene glycol).propane-1,2-diol in concentrations of 30-90 g/l was found to inhibit in vitro the growth of pityrosporum orbiculare, candida albicans, trichophyton rubrum, t. mentagrophytes var. interdigitale, and epidermophyton floccosum. these results are discussed in relation to the management of fungal skin diseases.19807434130
the antimycotic activity in vitro of five diols.the antimycotic activity of ethane-1,2-diol, propane-1,2-diol, butane-1,3-diol, pentane-1,5-diol, and hexane-2,5-diol in vitro against pityrosporum orbiculare, candida albicans, trichophyton rubrum, t. mentagrophytes var. interdigitale and epidermophyton floccosum was studied. ethane-1,2-diol had the lowest activity (mic of 40-100 g 1(-1)), and hexane-2,5-diol the highest activity (mic of 10-40 g 1(-1)). among, the higher diols there can be both effective antifungal agents and substances with a ...19807455861
tinea versicolor: ultrastructural studies on hypopigmented and hyperpigmented skin.punch biopsy specimens from 4 patients with confirmed diagnosis of tinea versicolor were investigated. hypopigmented, hyperpigmented and uninvolved sites from the same subject were compared in relation to ultrastructural alterations as a result of infection with malassezia furfur, by light, scanning, and transmission electron microscopy. hyperpigmented skin had thicker stratum corneum than hypopigmented but both were thicker than the uninvolved skin. a large number of tonofilaments were noticed ...19817195831
experimental infections in rabbits and humans with pityrosporum orbiculare and p. ovale.the purpose of this investigation was to produce experimental tinea versicolor in rabbits and humans with pityrosporum orbiculare and p. ovale. p. orbiculare and p. ovale were inoculated, with and without occlusion, on the inside of the ear in 10 male rabbits and on the upper arm in 10 patients with a history of tinea versicolor, and in 3 healthy volunteers. after 1 week tinea versicolor-like lesions were produced with both p. orbiculare and p. ovale in 8 of 10 rabbits. likewise experimental inf ...19817264365
amino acid metabolism of malassezia furfur.the mechanism responsible for the hypopigmentation which follows pityriasis versicolor (p.v.) infection has not yet been satisfactorily explained. this work was done in order to study the effect of malassezia furfur on the decomposition or the utilization of the amino acid tyrosine in vitro. no effect could be noted, which points to the assumption that the effect of the causative fungus of p.v. on melanogenesis is most probably due to the blocking of melanine synthesis by one of the product of m ...19817316405
histological and serological studies of pityrosporum orbiculare in cases of pityriasis versicolor. 19817014679
micro-aerophilic and anaerobic growth of pityrosporum species.pityrosporum orbiculare, p. ovale, and p. pachydermatis showed the same luxuriant growth when cultured under aerobic conditions, in an aerobic milieu with 7% co2, and under micro-aerophilic conditions. the species survived and even multiplied under strictly anaerobic conditions. these findings may explain how p. orbiculare and p. ovale can survive in the deeper parts of hair follicles. on a medium that enhanced the production of filaments in pityrosporum, filaments were more pronounced in the mi ...19817256488
[in vitro blastogenic response of lymphocytes in pityriasis capitis and dermatitis seborrheica (using pha-mitogen, pityrosporum ovale and bacteria)].63 patients with pityriasis capitis (pc) "dandruff" and seborrheic dermatitis (sd) as well as normal controls were studied. antigenicity was checked "in vitro" by the lymphocytic transformation test. a significant transformation in the pc to p. ovale was observed while in sd it was to stanphyloccocus and p. ovale. in view of results the authors suggest that there is a similar immunoalergic response in the host to those antigens. the clinic will differ according to the antigens. this is significa ...19816455574
[presence of pityrosporum ovale in the ear of newborn infants].lipophilic yeasts of the genus pityrosporum were found in random samples from the external ear of 7% of 101 neonates and 8% of 111 infants 3 days old. the yeasts were also found in 70.4% of 132 specimens from adult female external genitalia. there were no isolations of pityrosporum from 46 intravaginal specimens or samples of baby oil.19817256489
antigenic similarities and differences in genus pityrosporum.using the indirect immunofluorescence technique no differences were observed in intensity of staining when antisera against pityrosporum orbiculare and p. ovale or igg fractions of these were incubated with p. orbiculare and p. ovale cells. however, a weaker reaction was observed with these antisera and p. pachydermatis cells. with igg fractions the nonspecific fluorescence was minimized. fungal cells in biopsies from tinea versicolor lesions showed a brilliant staining with the igg fractions of ...19826172522
the frequency of pityrosporum orbiculare as a skin commensal among an israeli population. 19827177161
effects of reduced temperature on the components of human lymphocyte transformation responses to antigens.the present studies were designed to determine the site at which reduced temperature, such as that found at the skin surface, affects the lymphocyte transformation response to an antigenic stimulus. extracts of candida albicans and pityrosporum orbiculare were used as antigens since most normal subjects demonstrate positive lymphocyte responses to both. total lymphocyte transformation responses to both antigens were reduced and delayed at 34.5 as compared with 37 degrees c. the former temperatur ...19827049948
analysis of the lymphocyte transformation response to pityrosporum orbiculare in patients with tinea versicolor.lymphocyte transformation responses to pityrosporum orbiculare were compared in tinea versicolor patients and normal subjects with respect to the number of antigen responsive cells (arc) present, the first generation lymphocyte response (fglr), and the magnitude of the total response. a modest, but statistically significant decrease in the magnitude of the lymphocyte transformation response to p. orbiculare was found in the tinea versicolor group and appeared to be accounted for by a similar dec ...19827172495
the effect of benzoyl peroxide on cutaneous micro-organisms in vitro.the survival curves of cutaneous micro-organisms in the presence of benzoyl peroxide were investigated. all the curves exhibited a shoulder prior to exponential cell death. benzoyl peroxide was lethal to the cutaneous organisms tested and they varied in sensitivity increasing as follows: propionibacterium acnes, staphylococcus capitis, staph. epidermidis, staph. hominis, prop. avidum, prop. granulosum and pityrosporum ovale.19836874624
quantitative variations in distribution of pityrosporum orbiculare on clinically normal skin.the lipophilic yeast pityrosporum orbiculare has been cultured quantitatively, in 10 volunteers, from clinically normal skin on the chest, back, upper arm, lower leg, and dorsal aspect of the hand. the highest count was on the back (mean 333/cm2) and chest (mean 327/cm2). this was statistically significant higher than on the upper arm (mean 21/cm2), lower leg (mean 13/cm2), and dorsal aspect of the hand (mean 2/cm2). the variations in number of p. orbiculare parallels both regional variations in ...19836195869
class-specific antibodies in young and aged humans against organisms producing superficial fungal infections.class-specific antibodies (igg, iga and igm) against candida albicans, pityrosporum orbiculare and trichophyton rubrum were measured in the serum from twenty-one young subjects (aged 23-44) and twenty elderly subjects (aged 70-88) who did not have a history of significant superficial fungal infections. we found that (a) antibody to all three organisms was present in all subjects in both groups, (b) except for a reduced level of igm antibody against p. orbiculare, the elderly subjects demonstrate ...19836336945
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