Publications

excretion of attenuated polioviruses in children vaccinated with live oral poliovirus vaccine.	the excretion of attenuated polioviruses was studied in a group of nursery children vaccinated with 105tcd50 of each type of virus. the primovaccinated children were found to excrete type 1 poliovirus for 8 weeks, type 2 for 11 weeks after the vaccination with the type 1 + 2 bivaccine. poliovirus type 1 as eliminated by 78% and type 2 by 98% of the vaccinees. the separately administered type 3 was detectable for 6 weeks and was isolated from 100% of the vaccinees. the highest per cent of childre ...	1982	6282962
fulminant hepatic necrosis in an infant with perinatally acquired echovirus 21 infection.		1987	3822621
molecular epidemiology of echovirus 30 in taiwan, 1988-2008.	to investigate the molecular epidemiology of taiwanese echovirus 30 (e-30) strains, we analyzed the 876 bp sequence of the vp1 gene from 32 taiwanese strains isolated in 1988-2008, 498 reference sequences, and one echovirus 21 strain as the out-group. phylogenetic analysis detected six e-30 genotypes (designated gi-gvi) that had circulated globally during the past five decades. the genotypes varied widely in geographic distribution and circulation half-life. the gi, gii, and gv were ancient geno ...	2011	21369829
molecular epidemiological study of enteroviruses associated with encephalitis in children from india.	enteroviruses have been reported in encephalitis cases. however, clinical and epidemiological characteristics of enteroviruses in encephalitis are not fully established. we prospectively investigated 204 children with encephalitis over a period of 2 years (2009 to 2010) for enterovirus. enterovirus was detected in 45 specimens (22.1%); of these, 40 were typed by seminested reverse transcription-pcr (rt-pcr) and sequencing of the vp1 gene. molecular typing of enterovirus revealed the predominance ...	2012	22895040
congenital echovirus 21 infection causing fulminant hepatitis in a neonate.	enteroviral infection in pregnancy is common and there is growing evidence relating it to congenital anomalies and neonatal mortality. neonatal disease may range from unapparent infection to overwhelming systemic illness. passively acquired maternal serotype specific antibodies determine the severity of the disease in the newborn. a fatal case of congenital echovirus 21 infection, confirmed by pcr in the patient's blood and positive culture of the mother's stools, is reported. a sibling had symp ...	2013	23576650
identification and characterization of unrecognized viruses in stool samples of non-polio acute flaccid paralysis children by simplified vidisca.	the use of sequence independent methods combined with next generation sequencing for identification purposes in clinical samples appears promising and exciting results have been achieved to understand unexplained infections. one sequence independent method, virus discovery based on cdna amplified fragment length polymorphism (vidisca) is capable of identifying viruses that would have remained unidentified in standard diagnostics or cell cultures.	2014	25112200
clinical characteristics and molecular epidemiology of enterovirus infection in infants <3 months in a referral paediatric hospital of barcelona.	enterovirus (ev) infection is common in infants, but the information with regard to the molecular epidemiology and the associations between types and clinical variables is very scarce. this study includes 195 children <3 months old with fever, attended from march 2010 to december 2012 in an emergency department of a tertiary paediatric hospital in whom ev infection was confirmed by real-time pcr in blood and/or cerebrospinal fluid. clinical and epidemiological data was prospectively collected. i ...	2015	26003661
an outbreak of encephalitis associated with echovirus 19 in uttar pradesh, india, in 2011.	a sequence-independent single-primer amplification method and a modified enterovirus vp1 gene typing primer were used for identification of echovirus 19 and enterovirus 101, which remained undiagnosed by standard enterovirus molecular typing methods. six different serotypes were identified during this study, with the predominance of ecv 19 (n = 20) followed by echovirus 21 (n = 3), ev 69 and ev 101 (n = 2 each), coxsackievirus b5 and ecv 27 (n = 1 each). to our knowledge, this is the first repor ...	2016	26695770