Publications

TitleAbstractYear(sorted ascending)
Filter
PMID
Filter
feline leukemia virus: occurrence of viral antigen in the tissues of cats with lymphosarcoma and other diseases.felinie leutkemia viruts antigen is demonstrable by immunodiffusion with rabbit precipitating antiserum to purified felinie leukemia virus. the felinie leukemia virus antigen was found in the tissues of 25 of 33 cats with lymphosarcoma and of 5 of 13 cats with infectious peritonitis. its presence was correlated with the occurrence of felinie leukemia virus demonstrable by electron microscopy. the one clinically normal cat giving a positive test for feline leukemia virus antigen belonged to a hou ...19694981495
viral infection across species barriers: reversible alteration of murine sarcoma virus for growth in cat cells.infection of cat embryo cells by a centrifugally induced aggregate of murine sarcoma virus and feline leukemia virus gave rise to a defective, focus-forming virus which propagated in cat cells, but not in mouse cells. this virus, apparently enveloped with a feline leukemia virus coat, was later subjected to aggregation with murine leukemia virus, whereupon it regained the capacity for growth in mouse cells.19695793978
ultrastructural studies of feline leukemia virus. 19704991275
feline leukemia virus: purification from tissue culture fluids. 19705002006
methods for the detection of viral antigen and antibody to a feline leukemia virus (a preliminary report). 19705002008
feline leukemia virus detection in vitro. 19705467915
epidemiology of feline leukemia (lymphosarcoma). 19704376370
serological studies of the feline leukemia virus. 19704376371
feline leukemia virus: detection of group-specific viral antigen and infectious virus by a complement-fixation test. 19704376372
feline leukemia characterization of the virus. 19704376373
growth of feline leukemia virus in human, canine and porcine cells. 19704376374
induction of tumors in marmoset monkeys with st-feline fibrosarcoma virus. 19704376376
comparisons of virus-like particles from leukotic cattle to feline leukosis virus. 19704376380
trans-species rescue of defective genomes of murine sarcoma virus from hamster tumor cells with helper feline leukemia virus.this report describes a trans-species rescue of defective msv genome with helper leukemia virus derived from cats. this rescue was achieved by in vitro co-cultivation of hamster tumor cells with feline embryo cells in the presence of helper feline leukemia virus (felv), or by inoculation of tumor cells into felv-infected newborn cats. the rescued focus-forming viruses produced foci in feline embryo cultures but not in cultures of mouse, rat, and hamster species. one isolate was tested and found ...19704313195
physical alterations of a murine leukemia virus complex in mammalian cell cultures. 19704142388
productive infection and morphologic alteration of human cells by a modified sarcoma virus. 197011515085
infection and transformation of dog cells with a modified sarcoma virus.dog-embryo cell cultures were infected with a mixture of feline leukemia virus (fellv) and a modified murine (moloney) sarcoma virus msv(fellv). morphological alteration of the cells was observed 3 days post infection. virus progeny from the infected cultures increased 50- to 100-fold in foci of cellular alteration on dog cell cultures pretreated with diethylaminoethyl-dextran, but only twofold on cat embryo cultures similarly treated. the numbers of foci produced corresponded to a dual infectio ...197018605433
a fluorescent antibody technique for the detection of the group-specific antigen of feline leukemia virus in infected tissue-culture cells. 19714105993
isolation and characterization of two group-specific antigens from feline leukemia virus. 19714328488
specific inhibition of mammalian ribonucleic acid c-type virus deoxyribonucleic acid polymerases by rat antisera.inhibition of the ribonucleic acid (rna)- and deoxyribonucleic acid (dna)-dependent dna polymerase activities of mammalian c-type viruses was obtained with sera from rats bearing murine leukemia virus-induced transplant tumors. polymerase activities of nonmammalian (viper) c-type virus and murine mammary tumor virus were not inhibited by such sera nor by serum from a rat immunized with the dna polymerase of feline leukemia virus purified by isoelectric focusing. the latter serum appeared to inhi ...19714332148
helical nucleocapsid structure of the oncogenic ribonucleic acid viruses (oncornaviruses).negative staining of virions and isolated nucleoids from avian myeloblastosis virus, murine leukemia virus, murine mammary tumor virus, and feline leukemia virus reveals common internal structures. the majority of virions that are penetrated by phosphotungstate show spherical nucleoids with no apparent symmetry. in a small percentage of virions, two distinctive structures are found: (i) single strands (3 to 5 nm in diameter) which are presumed to be the nucleoprotein and are found randomly orien ...19714108573
epidemiologic implications of feline leukemia virus. 19714930304
comments on epidemiologic implications of feline leukemia virus. 19715575715
isolation of the nucleic acid of feline leukemia virus. 19715101019
comments on feline leukemia virus. 19715103499
virology and host range of feline leukemia virus. 19715108376
feline leukemia-virus infection of kittens: mortality associated with atrophy of the thymus and lymphoid depletion. 19715286051
serologic detection of feline leukemia virus antigens or antibodies. 19714995863
comments on epidemiologic aspects of feline leukemia virus. 19714930305
continuous long-term replication of feline leukemia virus (felv) in an established canine cell culture (mdck). 19724621402
theta particles: a structure found in hamster sarcoma virus.hamster sarcoma virus (hasv), a ribonucleic acid tumor virus, pelleted from tissue culture fluid manifests type c morphology by electron microscopy. however, if virus is first concentrated by polyethylene glycol or ammonium sulfate followed by density gradient banding, the virus shows a dramatically atypical barred core structure, termed "theta particles." this structure suggests a condensation of the ribonucleoprotein into a flat disc. atypical particles are found with hasv and not in similarly ...19724116139
major group-specific protein of rat type c viruses.the major internal protein of a rat type c virus pseudotype of murine sarcoma virus, msv(ralv), was purified by isoelectric focusing (pi = 8.6) and used to prepare antibody in guinea pigs. the protein was identified by its reaction with antisera reactive with the mammalian type c virus group-specific (gs) antigenic determinant, gs-3. the guinea pig antisera mainly contained species-specific (gs-1) antibody for reactions in gel diffusion with other type c viruses were limited to those of rat orig ...19724117346
rescue of the murine sarcoma virus genome from non-producer cells by the rd-114 type c virus. 19724358036
feline leukemia. 19724376153
detection and assay of feline leukemia virus (felv) by a mixed-culture cytopathogenicity method. 19724333572
cytopathogenic test for feline leukemia virus infections.a mixed culture cytopathogenic effect with the development of multinucleated giant cells in feline leukemia virus-infected cultures after cocultivation with xc cells is described. this cytopathogenic effect has been utilized as a convenient visual marker for the detection and assay of feline leukemia virus in feline and canine embryo fibroblasts as well as in a canine tumor cell line, m-132-1. comparison of the cytopathogenic reaction in the three cell lines indicates that the reaction is more r ...19724336663
induction of neoplasms by viruses in marmoset monkeys. 19724342234
tumor induction in squirrel monkeys by the st strain of feline sarcoma virus. 19724342616
nucleotide composition of the rna from rd-114 virions. 19724342708
a rapid direct radioimmunoassay for type c virus group-specific antigen and antibody. 19724343114
acute leukemia in identical twins: search for viral and leukemia-associated antigens. 19724343478
demonstration of antibody in cat sera to feline oncornavirus by complement-fixation inhibition. 19724343689
syncytial assay for the putative human c-type virus, rd-114, utilizing human cells transformed by rous sarcoma virus. 19724343952
poly u tracts absent from viral rna. 19724344177
location of feline leukemia-sarcoma group-specific antigen in infected human tissue culture cells.feline leukemia-sarcoma group-specific antigens were located in human embryo cells infected with feline leukemia and feline sarcoma viruses. this was done by using the fluorescent-antibody and enzyme-labeled antibody techniques at both light and electron microscopic levels. the antigens were found to be exclusively intracytoplasmic, diffuse, and located in discrete punctate foci.19724344220
review of viral disease of cats. 19724344966
antigenic comparison of bovine type c virus with murine and feline leukemia viruses. 19724345040
revertants of mouse cells transformed by murine sarcoma virus. i. characterization of flat and transformed sublines without a rescuable murine sarcoma virus. 19724117128
immunologic reactivity of the cat: immunosuppression in experimental feline leukemia. 19724346537
natural history studies of the feline rna tumor virus genoma. i. detection of group specific antigen and c-type particles. 19724349825
search for oncogenes in human rhabdomyosarcoma cells. 19724349826
human cancer in households containing cats with malignant lymphoma. 19724350192
feline malignant lymphoma: environmental factors and the occurrence of this viral cancer in cats. 19724350193
reversible inactivation of the deoxyribonucleic acid polymerase of rauscher leukemia virus.rauscher leukemia virus deoxyribonucleic acid polymerase is reversibly inactivated by 6 m guanidine-hydrochloride. gel filtration in 6 m guanidine-hydrochloride reveals that the viral deoxyribonucleic acid polymerase consists of a single polypeptide chain of approximately 70,000 molecular weight.19724117352
ribonuclease h: a ubiquitous activity in virions of ribonucleic acid tumor viruses.ten ribonucleic acid (rna) tumor viruses grown in five different host cell species and three non-oncogenic viruses from three different virus groups have been examined for ribonuclease h content. three different substrates were used to assay ribonuclease h: calf thymus [(3)h]rna-deoxyribonucleic acid (dna) hybrid prepared with denatured calf thymus dna and escherichia coli dna-directed rna polymerase, (3)h-polydenylic acid [(3)h-poly(a)] complexed to polydeoxythymidylic acid [poly(dt)], and (3)h ...19724118867
specificity of antibody to the rd-114 viral polymerase. 19734121714
molecular relatedness of mammalian rna tumor viruses as determined by dna hybridization.each of six mammalian c-type viruses-including two feline leukemia viruses, three murine leukemia viruses, and the human "candidate" virus rd-114-can be distinguished from each other by hybridizing dna synthesized by viral reverse transcriptase with viral rna. characterization of the dna . rna hybrids by hydroxylapatite chromatography revealed nucleotide sequence diversity among the viruses, detectable both by the amount of cross-hybridization and by the decreased thermal stability of heterologo ...19734122422
endogenous type c virus from a cat cell clone with properties distinct from previously described feline type c virus. 19734122424
isolation of rd-114-like oncornavirus from a cat cell line.a clone of cells derived from a continuous line of cat cells (ccc) spontaneously produced an rna c-type virus (ccc virus) which did not have the group-specific antigen of the standard strains of feline leukemia viruses but did have that of the rd-114 virus. single-hit infection of a virus yielding ccc cell with only the feline leukemia virus pseudotype of murine sarcoma virus [msv(felv)] resulted in the release of a pseudotype of msv coated with the ccc virus envelope. host range, transmission o ...19734123287
feline leukemia and rd-114 virus group-specific proteins: comparison of amino terminal sequence.the major internal virion polypeptide from feline and rd-114 type c viruses has been subjected to amino terminal sequence analyses with the beckman automated sequencer. these proteins, as well as their homologs in rat and mouse viruses, begin with the sequence prolylleucylarginyl (pro-leu-arg). virus rd-114 differs from conventional feline type c viruses that show about 80 percent relatedness based on calculation of the minimum number of base changes to give equivalent coding for the protein seg ...19734123999
structural proteins of oncogenic ribonucleic acid viruses. interspec ii, a new interspecies antigen. 19734124987
comparative serological studies on type c viruses of various mammals. 19734125728
utilization of mammalian 70s rna by a purified reverse transcriptase from human myelocytic leukemic cells. 19734126334
immunological relationship of dna polymerase from human acute leukaemia cells and primate and mouse leukaemia virus reverse transcriptase. 19734126783
expression of endogenous rna c-type virus group-specific antigens in mammalian cells.highly sensitive and specific radioimmunoassays are described for quantitation of the intraspecies determinants of several mammalian c-type viral group-specific (gs) antigens. an interspecies (gs-3) immunoassay has been developed which has both the broad reactivity and great sensitivity necessary for detection of c-type viruses where intraspecies gs assays are not available. by using these immunoassays, the expression of endogenous virus-specified gs antigens in mammalian cells of different spec ...19734127032
determinants of the host range of feline leukaemia viruses. 19734127732
polypeptides of mammalian oncornaviruses. i. isolation and serological analysis polypeptides from murine and feline c-type viruses. 19734127971
control of group-specific antigen synthesis by the defective gazdar murine sarcoma virus genome. 19734350230
isolation of human amnion cells transformed by rescuable murine sarcoma virus. 19734350532
feline virus-induced tumors and the immune response: recent developments. 19734350543
current enigmas in cancer research. 19734351100
detection of feline syncytia-forming carrier state with a microimmunodiffusion test. 19734346617
oncogenic activity of feline fibrosarcoma virus in newborn pigs. 19734348004
syncytial giant cell focus assay for viruses derived from feline leukemia and a simian sarcoma. 19734348580
surface antigens on cat leukemic cells induced by feline leukemia virus: area density and antibody-binding affinity.the binding of autologous bovine antibody to feline leukemia virus-induced cell surface antigens (fecsa) on cat leukemia cells was studied by performing certain titration procedures with a mixture of immune and normal sera labeled with different iodine radioisotopes (paired-label technique). by using plots of titration data which conformed to linear equations derived from the mass action law, we determined the following constants. (i) the density of fecsa was 2.03 x 10(6) sites per cell, or 5,23 ...19734349492
primate rna tumor virus-like dna synthesized endogenously by rna-dependent dna polymerase in virus-like particles from fresh human acute leukemic blood cells.a particle of discrete biochemical composition was purified from fresh, unfrozen peripheral blood leukocytes of human patients with acute myeloblastic leukemia. this particle endogenously synthesized dna by use of an rna primer and template. about half of the dna sequences synthesized in the presence of actinomycin d hybridized to rna isolated from type-c sarcoma viruses of primates or mice; lower annealing values were obtained with rna isolated from other sarcoma or leukemia viruses. the result ...19734131745
[evidence for the existence of different antigenic determinants of the interspecies type in mammalian rna-c-type tumor viruses. comparative serological studies on viruses of various animal species including a virus suggested to be of human origin (author's transl)]. 19734131792
interspecies infection by feline leukemia virus: serial cell-free transmission in dogs of malignant lymphomas induced by feline leukemia virus. 19734360147
viral envelope antigens of the viruses of feline leukemia-sarcoma complex. 19734360149
significance of leukemia in animals for the human disease. 19734360150
structural and serological studies on animal 'c-type particles' and their implications for demonstrating corresponding viruses in man. 19734360151
studies on the relationship of rna viruses to the origin of leukemia and solid tumors of animals and man. 19734360152
electron microscopy of feline leukaemia virus rna. 19734360153
electron microscopy of early interactions between feline leukaemia virus and cells in tissue culture. 19734360154
continuing studies of feline sarcoma virus-induced tumors in nonhuman primates. 19734360157
simian sarcoma virus: oncogenicity, focus assay, presence of associated virus, and comparison with avian and feline sarcoma virus-induced neoplasia in marmoset monkeys. 19734360159
relationship between humoral antibodies and the failure to develop progressive tumors in cats injected with feline sarcoma virus (fsv). 19734360194
detection of the feline leukemia virus and other mammalian oncornaviruses by immunofluorescence. 19734360195
studies of human cells infected by leukemia viruses. 19734360197
feline leukaemia virus infection--the spectrum of associated disease and its relevance to the pathogenesis and immunology of leukaemia. 19734360200
specificity of the dna product of rna-dependent dna polymerase in type c viruses. ii. quantitative analysis.a number of mammalian type c viruses were analyzed for relatedness by the technique of dna.rna hybridization. viral dnas were prepared in single-stranded form from complexes with 70s viral rna formed during endogenous polymerase reactions. extent of hybridization was assayed with the single-strand nuclease (s-1) from aspergillus oryzae. results obtained indicated a high degree of viral specificity, with significant cross-reactions being observed only with viruses obtained from within a species, ...19734129928
the 60 to 70s rna and reverse transcriptase of simian sarcoma and simian sarcoma-associated viruses. 19734130033
antibodies to feline oncornavirus group-specific antigens in feline sera. 19734130403
antigenic determinants shared by polypeptides of feline leukaemia virus. 19734130406
early lesions in cats inoculated with feline leukemia virus. 19734345148
fusion of a rous sarcoma virus transformed human cell line, kc, by rd-114 virus. 19734357937
rd 114 virus-specific sequences in feline cellular rna: detection and characterization.rna extracted from cat cells contains sequences homologous to rd-114 viral rna. the sequences are measured by molecular hybridization with a single-stranded dna probe synthesized by the virion polymerase using the endogenous viral rna as template. viral-specific rna has been detected in all cells of cat origin tested thus far, but not in cells of other animals, except for the virus-producing human rhabdomyosarcoma cell, rd-114. the extent of hybridization of the dna probe to cellular rna was equ ...19734358169
horizontal transmission of feline leukaemia virus. 19734147636
feline rna tumor viruses. 19734377948
immunosuppression and experimental lymphoma. 19734351400
Displaying items 1 - 100 of 1841