Publications
Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
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encephalitis caused by pathogens transmitted through organ transplants, united states, 2002-2013. | the cause of encephalitis among solid organ transplant recipients may be multifactorial; the disease can result from infectious or noninfectious etiologies. during 2002-2013, the us centers for disease control and prevention investigated several encephalitis clusters among transplant recipients. cases were caused by infections from transplant-transmitted pathogens: west nile virus, rabies virus, lymphocytic choriomeningitis virus, and balamuthia mandrillaris amebae. in many of the clusters, iden ... | 0 | 25148201 |
rodents and risk in the mekong delta of vietnam: seroprevalence of selected zoonotic viruses in rodents and humans. | in the mekong delta in southern vietnam, rats are commonly traded in wet markets and sold live for food consumption. we investigated seroprevalence to selected groups of rodent-borne viruses among human populations with high levels of animal exposure and among co-located rodent populations. the indirect fluorescence antibody test (ifat) was used to determine seropositivity to representative reference strains of hantaviruses (dobrava virus [dobv], seoul virus [seov]), cowpox virus, arenaviruses ( ... | 0 | 25629782 |
development of a new hydrogen peroxide–based vaccine platform. | safe and effective vaccines are crucial for maintaining public health and reducing the global burden of infectious disease. here we introduce a new vaccine platform that uses hydrogen peroxide (h(2)o(2)) to inactivate viruses for vaccine production. h(2)o(2) rapidly inactivates both rna and dna viruses with minimal damage to antigenic structure or immunogenicity and is a highly effective method when compared with conventional vaccine inactivation approaches such as formaldehyde or β-propiolacton ... | 0 | 22635006 |
cell culture and electron microscopy for identifying viruses in diseases of unknown cause. | during outbreaks of infectious diseases or in cases of severely ill patients, it is imperative to identify the causative agent. this report describes several events in which virus isolation and identification by electron microscopy were critical to initial recognition of the etiologic agent, which was further analyzed by additional laboratory diagnostic assays. examples include severe acute respiratory syndrome coronavirus, and nipah, lymphocytic choriomeningitis, west nile, cache valley, and he ... | 0 | 23731788 |
blockade of interferon beta, but not interferon alpha, signaling controls persistent viral infection. | although type i interferon (ifn-i) is thought to be beneficial against microbial infections, persistent viral infections are characterized by high interferon signatures suggesting that ifn-i signaling may promote disease pathogenesis. during persistent lymphocytic choriomeningitis virus (lcmv) infection, ifnα and ifnβ are highly induced early after infection, and blocking ifn-i receptor (ifnar) signaling promotes virus clearance. we assessed the specific roles of ifnβ versus ifnα in controlling ... | 0 | 25974304 |
toll-like receptor 7 is required for effective adaptive immune responses that prevent persistent virus infection. | tlr7 is an innate signaling receptor that recognizes single-stranded viral rna and is activated by viruses that cause persistent infections. we show that tlr7 signaling dictates either clearance or establishment of life-long chronic infection by lymphocytic choriomeningitis virus (lcmv) cl 13 but does not affect clearance of the acute lcmv armstrong 53b strain. tlr7(-/-) mice infected with lcmv cl 13 remained viremic throughout life from defects in the adaptive antiviral immune response-notably, ... | 0 | 22704624 |
lymphocytic choriomeningitis virus-associated meningitis, southern spain. | lymphocytic choriomeningitis virus (lcmv) was detected in 2 patients with acute meningitis in southern spain within a 3-year period. although the prevalence of lcmv infection was low (2 [1.3%] of 159 meningitis patients), it represents 2.9% of all pathogens detected. lcmv is a noteworthy agent of neurologic illness in immunocompetent persons. | 0 | 22515986 |
solid organ transplant-associated lymphocytic choriomeningitis, united states, 2011. | three clusters of organ transplant-associated lymphocytic choriomeningitis virus (lcmv) transmissions have been identified in the united states; 9 of 10 recipients died. in february 2011, we identified a fourth cluster of organ transplant-associated lcmv infections. diabetic ketoacidosis developed in the organ donor in december 2010; she died with generalized brain edema after a short hospitalization. both kidneys, liver, and lung were transplanted to 4 recipients; in all 4, severe posttransplan ... | 0 | 22839997 |
persistence of lymphocytic choriomeningitis virus in immune animals and its relation to immunity. | in some apparently healthy mice the virus of lymphocytic choriomeningitis persisted for a considerable period of time after recovery, in the blood, urine, and nasal secretions, while in other mice it soon became undemonstrable. it is possible that the persistence of the virus is due to lesions in the lungs, liver, and kidneys. the immunity to lymphocytic choriomeningitis in mice does not seem to depend upon the presence of virus in the blood and the organs tested. no antivirus was detected in se ... | 1936 | 19870509 |
immunization of guinea pigs with a modified strain of lymphocytic choriomeningitis virus. | a strain of choriomeningitis virus which was highly virulent for guinea pigs, as isolated from a naturally infected white mouse, has been markedly attenuated for guinea pigs by serial intracerebral passage through white mice. the change of virulence occurred before the 8th serial passage. the modified virus as a rule produces fever in guinea pigs but no other symptoms, and the infection is followed by a very solid immunity. parallel passages of the same strain through guinea pigs have maintained ... | 1937 | 19870665 |
characteristics of a strain of lymphocytic choriomeningitis virus encountered as a contaminant in tissue cultures of rabies virus. | a strain of lymphocytic choriomeningitis virus has been encountered, which grows readily in mouse embryo, serum, tyrode culture media. its origin is not definitely known but appears to be either the mouse brain tissue or, more probably, the monkey serum. this strain gives clear cut results on filtration tests through elford membranes, establishing the size of the virus, according to formula, as 33 to 50 mmicro. the strain shows a high and uniform virulence in w-swiss mice. this appears to be due ... | 1940 | 19870952 |
studies in rodent poliomyelitis : i. further experiments with the murine strain of sk poliomyelitis virus. | 1. sk murine virus maintained over more than 200 serial mouse passages increased in virulence for mice from an initial intracerebral titer of about 1:1 million to a maximum titer of not less than 1:1 billion dilution activity. 2. following intracerebral injection with murine virus of remote mouse passages, 5 of 13 rhesus monkeys developed a characteristic encephalitic syndrome. repeated intravenous injection of massive doses of virus caused localized flaccid paralysis in 2 of 14 monkeys. 3. intr ... | 1942 | 19871210 |
propagation of lymphocytic choriomeningitis virus in embryonated hens' eggs. | 1947 | 20344614 | |
myositis in mice following intramuscular injection of viruses of the mouse encephalomyelitis group and of certain other neurotropic viruses. | a study has been made of the local effects following intramuscular injection of various neurotropic viruses. early massive necrosis of muscle fibers accompanied by edema and acute inflammatory reaction is produced by jungeblut's sk virus even in low concentrations. similar but more slowly developing lesions follow the introduction of mouse encephalomyelitis gd-vii and fa strains. strain 4727 (to type) produces inflammatory changes with fibrosis in the intermuscular septa and necrosis of scattere ... | 1949 | 18099166 |
active immunization of mice with ultraviolet-inactivated lymphocytic choriomeningitis virus vaccine and results of immune serum therapy. | 1949 | 15392986 | |
multiplication of certain neurotropic viruses in the rabbit eye following intraocular inoculation. | lymphocytic choriomeningitis virus and semliki forest virus readily multiply in the rabbit eye following inoculation into the vitreous. less than 10 mouse ld(50) of lcm virus was sufficient to induce multiplication in the eye, whereas, approximately 1000 ld(50) of sfv was required to initiate infection. both viruses multiplied in the rabbit eye as an inapparent infection. little or no virus could be recovered from the optic nerves or brains of the rabbits, although virus was present in high tite ... | 1950 | 15395572 |
[properties of two strains of lymphocytic choriomeningitis virus isolated in 1948]. | 1950 | 14772351 | |
[lymphocytic choriomeningitis virus (armstrong) diseases in hungary]. | 1950 | 14782999 | |
[etiologic and epidemic significance of lymphocytic choriomeningitis virus in hungary]. | 1950 | 14827542 | |
lymphocytic choriomeningitis virus from gray mice trapped in a rural area. | 1951 | 14840007 | |
response of infant and adult mice to lymphocytic choriomeningitis virus infection. | 1951 | 14891982 | |
[comparative study of the lymphocytic choriomeningitis virus: human (w.e. armstrong) and animal (guinea pig pneumopathy)]. | 1951 | 14916244 | |
the growth of lymphocytic choriomeningitis virus in the developing chick embryo. | 1954 | 13190122 | |
[experimental study of seven strains of lymphocytic choriomeningitis virus of the armstrong type isolated in man]. | 1955 | 13261419 | |
[specific inactivation of antibody production in lymphocytic choriomeningitis-virus infected mice]. | 1955 | 13286883 | |
[fatal course of a lymphocytic choriomeningitis virus infection]. | 1956 | 13330499 | |
lymphocytic choriomeningitis virus in mouse neoplasms. | 1956 | 13357942 | |
[resistence of the lymphocytic choriomeningitis virus to the oligodynamic action of silver]. | 1956 | 13389931 | |
lymphocytic choriomeningitis virus as related to chemotherapy studies and to tumor induction in mice. | 1957 | 13488294 | |
[studies on infection of house rodents with neuroviruses. i. infection of house mice with lymphocytic choriomeningitis virus]. | 1958 | 13569997 | |
[research on the stability of lymphocytic choriomeningitis virus to heat]. | 1959 | 13650540 | |
[neutralization technic for lymphocytic choriomeningitis virus in mouse]. | 1959 | 13650541 | |
[course of lymphocytic choriomeningitis virus after peripheral inoculation]. | 1959 | 13650564 | |
relationships between lymphocytic choriomeningitis virus, amethopterin, and an amethopterin-resistent lymphocytic neoplasm in mice. | 1959 | 13655063 | |
[significance of complement-fixing & neutralizing antibodies for the diagnosis of lymphocytic choriomeningitis virus infections]. | 1959 | 13671973 | |
immunologic response to lymphocytic choriomeningitis virus in lethally irradiated mice treated with bone marrow. | 1960 | 13779228 | |
cytopathogenicity and plaque formation with lymphocytic choriomeningitis virus. | 1960 | 13799010 | |
cytological changes by lymphocytic choriomeningitis virus in the human amnion cells. | 1961 | 13941424 | |
the role of immunological tolerance in neonatal infection of mice with lymphocytic choriomeningitis virus. | 1961 | 13716108 | |
orchitis, parotitis and meningoencephalitis due to lymphocytic-choriomeningitis virus. | 1961 | 14464883 | |
[detection of lymphocytic choriomeningitis viruses with the aid of an indirect fluorescence antibody method]. | 1961 | 14491386 | |
[antagonism between the lymphocytic choriomeningitis virus and rickettsia prowazekii. preliminary note]. | 1962 | 14491345 | |
parotitis, orchitis, and meningoencephalitis due to lymphocytic choriomeningitis virus. | 1962 | 13869918 | |
[study of the pathogenicity of the lymphocytic choriomeningitis virus. i. skin reactivity in the rabbit]. | 1962 | 13982380 | |
the foot pad reaction of mice to lymphocytic choriomeningitis virus. | 1962 | 14449211 | |
lymphocytic choriomeningitis infection in neonataily thymectomized mice bearing diffusion chambers containing thymus. | normal, nonoperated swiss mice which had been inoculated intracerebrally with lymphocytic choriomeningitis virus showed a 100-percent mortality within 8 days after virus challenge. neonatally thymectomized mice, with or without empty intraperitoneal diffusion chambers, were protected from the lethal effects of the virus, with no animals dying within 14 days after inoculation. cell-tight millipore diffusion chambers containing newborn thymic tissue, implanted intraperitoneally into neonatally thy ... | 1963 | 17748162 |
interference between lymphocytic choriomeningitis virus and the leukemia-transmitting agent of leukemia l2c in guinea pigs. | 1963 | 14029922 | |
interference between lymphocytic choriomeningitis virus and the leukemia-transmitting agent of leukemia l2c in guinea pigs. | 1963 | 13958071 | |
[studies on the experimental pathogenicity of the lymphocytic choriomeningitis virus. iii. a directly visible inflammatory reaction in the mouse. viral edema of the hind leg]. | 1963 | 13982379 | |
increased susceptibility of mice to lymphocytic choriomeningitis virus after peripheral inoculation. | 1963 | 14081355 | |
[studies on the experimental pathogenicity of lymphocytic choriomeningitis virus. iv. mortality level of mice following subcutaneous plantar inoculation]. | 1963 | 14090348 | |
[studies of the experimental pathogenic capacity of the lymphocytic choriomeningitis virus. v. distribution of the mortality of mice during local reactions]. | 1963 | 14093786 | |
pathogenesis of rabies. | the authors have investigated the spread of fixed and street strains of rabies virus from the site of injection to the central nervous system and salivary glands in various animal species. the results indicate conclusively that rabies virus is ordinarily transmitted from the site of exposure to the central nervous system via the peripheral nerves but that other than nerve transmission may occur in young animals, in highly susceptible species or in animals whose resistance has been altered by tra ... | 1963 | 14107754 |
[on the spread of lymphocytic choriomeningitis virus in west germany]. | 1964 | 14117089 | |
[local titration of the lymphocytic choriomeningitis virus in mice. i. position of the problem. methods. "all or nothing" treatment]. | 1964 | 14141563 | |
[studies on the experimental pathogenic power of the lymphocytic choriomeningitis virus. vi. mortality of mice according to method of inoculation and dose]. | 1964 | 14145244 | |
[local titration of the lymphocytic choriomeningitis virus in mice. ii. quantitative study by the latency curve method]. | 1964 | 14145258 | |
protection against the lethal effect of lymphocytic choriomeningitis virus in mice by neonatal thymectomy. | 1964 | 14156324 | |
[local titration of the lymphocytic choriomeningitis virus in mice. iii. liaison between the duration or the extent of the local reaction and the concentration of inoculated viruses. theoretical and practical implications]. | 1964 | 14158907 | |
[studies on the experimental pathogenic power of the lymphocytic choriomeningitis virus. vii. allergy in local reactions in mice and conditions for demonstrating it]. | 1964 | 14190393 | |
[lymphocytic choriomeningitis virus infection in mice thymectomized shortly after birth]. | 1964 | 14231805 | |
immunofluorescent studies of the histopathogenesis of lymphocytic choriomeningitis virus infection. | lcm virus antigen was visualized in infected tissue cultures and mouse tissues by the direct immunofluorescent procedure. in all instances, antigen was localized to the cytoplasm. in intracerebrally infected mice, antigen was almost completely restricted to meninges, choroid plexus, and ependyma; at no time were neurons involved. mice infected by intraperitoneal inoculation of a viscerotropic strain demonstrated antigen chiefly in liver parenchyma, splenic reticulum, bronchi, and alveolar cells. ... | 1964 | 14247723 |
encephalitis syndrome of lymphocytic choriomeningitis virus infection. | 1964 | 14072669 | |
[spread of the lymphocytic choriomeningitis virus among west german mice. i. investigations mostly on domestic mice (mus musculus)]. | 1964 | 5831628 | |
[on the spread of lymphocytic choriomeningitis virus among mice in west germany. ii. studies of mice except mus musculus]. | 1964 | 5831889 | |
detection of a lymphocytic choriomeningitis component in rabies virus preparations. | 1965 | 5848338 | |
[sero-epidemiologic investigation of antibodies to the lymphocytic choriomeningitis virus in children]. | 1965 | 5856788 | |
role of the central nervous system in fatal murine lymphocytic choriomeningitis. (brief report). | 1965 | 5882950 | |
immunological tolerance to viruses. | 1965 | 4953302 | |
lymphocytic-choriomeningitis virus in hamster tumor: spread to hamsters and humans. | a passage line of a spontaneous hamster fibrosarcoma is contaminated by the virus. of lymphocytic choriomeningitis. tumors from animals receiving implants when newborn contain high titers of infectious lymphocytic-choriomeningitis virus and complement-fixing antigen, and hamsters receiving implants when weanlings develop high titers of complement-fixing antibody against lymphocytic-choriomeningitis virus. in contrast with the specific reactions of tumorous hamsters to the initiating virus in vir ... | 1965 | 4953610 |
[plaque and plaque inhibition technics in cell cultures for identification of the lymphocytic choriomeningitis virus]. | 1965 | 4955093 | |
demonstration of vaccinia, lymphocytic choriomeningitis and rabies viruses in the leucocytes of experimentally infected animals. | 1965 | 4956729 | |
[study of the strain of lymphocytic choriomeningitis virus isolated from ix. ricinus ticks gathered in the western regions of the ukrainian ssr]. | 1965 | 4959070 | |
effect of certain murine pathogens on phagocytic activity. | 1965 | 4283903 | |
the growth, reproduction and mortality of mice made immunologically tolerant to lymphocytic choriomeningitis virus by congenital infection. | 1965 | 14269251 | |
inability of nucleic acid analogues to inhibit the synthesis of lymphocytic choriomeningitis virus. | 1965 | 14295437 | |
biophysical and biochemical characterization of lymphocytic choriomeningitis virus. 1. density gradient studies. | 1965 | 14295438 | |
biophysical and biochemical characterization of lymphocytic choriomeningitis virus. 2. partial purification by differential centrifugation and fluorocarbon techniques. | 1965 | 14295439 | |
in vivo antiviral activity of 1,3-bis(2-chloroethyl)-1-nitrosourea. | a prolongation in the lives of swiss mice inoculated intracerebrally with lymphocytic choriomeningitis virus (lcm) was observed after treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea (bcnu). a variety of treatment schedules, including therapy once or twice daily up to 17 days and single treatments at various times after virus inoculation, were employed. virus titers ranging to greater than 10(4) were detected in the blood and brains of surviving drug-treated animals. in three comparative stud ... | 1965 | 14339266 |
some nuclear-substituted derivatives of alpha-methyldopa. | 1966 | 4291024 | |
in vitro studies on the antiviral activity of 1, 3-bis(2-chloroethyl)-1-nitrosourea. | chemotherapy experiments carried out in vitro demonstrated that 1,3-bis(2-chloroethyl)-1-nitrosourea (bcnu) was active against lymphocytic choriomeningitis virus and had an equivocal antiviral effect on semliki forest, herpes simplex, and vaccinia viruses. no antiviral effect was observed with bcnu against western equine encephalomyelitis, polio, and parainfluenza (ha-1) viruses. activity of the drug was determined by inhibition of viral-induced cytopathogenic effect in kb or chick embryo cells ... | 1966 | 4291237 |
viruses in the aetiology of acute appendicitis. | 1966 | 4162203 | |
rabies and lymphocytic choriomeningitis virus (lcmv) infection of tissue culture; enhancing effect of lcmv. | 1966 | 4961010 | |
enhancement of rabies virus infection by lymphocytic choriomeningitis virus. | 1966 | 4957203 | |
immunofluorescent detection of antibody to lymphocytic choriomeningitis virus in man. | 1966 | 4958095 | |
methanol precipitation of lymphocytic choriomeningitis virus. | 1966 | 4958921 | |
multiplication of lymphocytic choriomeningitis virus in suspension cultures of earle's strain l cells. | 1966 | 4958922 | |
lymphocytic choriomeningitis. | 1966 | 5907690 | |
interference between lymphocytic choriomeningitis and rauscher leukemia in mice. | 1966 | 5923905 | |
epidemic nonmeningitic lymphocytic-choriomeningitis-virus infection. an outbreak in a population of laboratory personnel. | 1966 | 5948615 | |
immunofluorescence study of the carrier state and mechanism of vertical transmission in lymphocytic choriomeningitis virus infection in mice. | 1966 | 5331383 | |
immunofluorescence study of the mechanism of resistance to superinfection in mice carrying the lymphocytic choriomeningitis virus. | 1966 | 5331384 | |
plaque assay for lymphocytic choriomeningitis virus based on hemadsorption interference. | 1967 | 4987174 | |
reproducible plaquing system for rabies, lymphocytic choriomeningitis,k and other ribonucleic acid viruses in bhk-21-13s agarose suspensions. | bhk21/13s-agarose suspension cultures provide an excellent plaquing system for rabies and lymphocytic choriomeningitis viruses. the system has facilitated accurate and reproducible assay of serum neutralization and cloning of these viruses. rubella, reo, and kern canyon viruses may also be assayed by this technique. | 1967 | 4987176 |
lymphocytic choriomeningitis: production of antibody by "tolerant" infected mice. | newborn mice infected with lymphocytic choriomeningitis virus are not immunologically tolerant to the agent but, rather, appear to make antibody to the virus. this antibody was detectable only in the kidneys, where presumably it had been deposited in the glomeruli in the form of complexes of antibody, virus, and complement. | 1967 | 4862090 |
antiviral activity of higher plants and propionin on lymphocytic choriomeningitis infection. | 1967 | 4961253 | |
a carrier state of lymphocytic choriomeningitis virus in l cell cultures. | 1967 | 4961982 | |
protective effect of anti-lymphocytic serum on murine lymphocytic choriomeningitis. | 1967 | 4962203 | |
a new method for the titration of lymphocytic choriomeningitis viruses. | 1967 | 4970514 | |
biophysical and biochemical characterization of lymphocytic choriomeningitis virus. 3. thermal and ultrasonic sensitivity. | 1967 | 4970518 |