Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| viral inactivation of human osteochondral grafts with methylene blue and light. | cartilage injury is one of the most common disorders of synovial joints. fresh osteochondral allografts are becoming a standard treatment; however, they are supply constrained with a potential risk of disease transmission. there are no known virucidal processes available for osteochondral allografts and most methods presently available are detrimental to cartilage. methylene blue light treatment has been shown to be successful in the literature for viral inactivation of fresh frozen plasma. the ... | 0 | 26069682 |
| isolation of mucosal disease virus by tissue cultures in mixture 199, morgan, morton and parker. | 1959 | 13634044 | |
| identification of a bovine mucosal-disease virus isolated in sweden as myxovirus para-influenzae 3. | 1960 | 18990778 | |
| separation of a soluble antigen and infectious particles of bovine viral diarrhea viruses and their relationship to hog cholera. | a soluble antigen present in infectious tissue culture fluids was separated from the infective virus particle by ultracentrifugation of two serologically related strains of bovine viral diarrhea viruses, nadl-md and oregon c24v. neutralizing antibodies against the two viruses were absent in four hog cholera antisera, but present in significant titer in the commercially prepared antiserum. precipitin tests utilizing the agar double diffusion technique formed a single line of identity between the ... | 1963 | 17649440 |
| demonstration of an antigenic relationship between hog cholera and bovine viral diarrhea viruses by immunofluorescence. | specific staining of antigen within bovine embryo kidney tissue culture cells, infected with either oregon c24v or nadl-md bovine viral diarrhea virus, was accomplished using fluorescein-conjugated swine anti-hog cholera or bovine antiviral diarrhea globulin. also specific staining of antigen within pig kidney tissue culture cells, infected with hog cholera virus, was accomplished using the same two types of conjugates. specificity was confirmed by appropriate controls. the authors found immunof ... | 1963 | 17649449 |
| attempts to recover bovine mucosal disease virus from artificially infected pigeons. | 1963 | 13961385 | |
| properties of some viruses of the mucosal disease-virus diarrhea complex. | 1963 | 13993561 | |
| noncytopathogenic bovine viral diarrhea viruses detected and titrated by immunofluorescence. | noncytopathogenic (ncp) bovine viral diarrhea (bvd) disease agents can be detected and titrated in tissue culture systems by a method employing immunofluorescence. cytopathogenic (cp) and ncp viruses cross react with fluorescein-conjugated serum globulins produced against either cp and ncp viruses, but the fluorescence is more intense in the homologous system. serum neutralization titers of sera against both cp and ncp groups were compared for both groups of viruses, and results of cross reactio ... | 1964 | 17649508 |
| the properties and classification of bovine viral diarrhea virus. | examination of the c24v (oregon) and mac a (ontario) strains of bovine viral diarrhea viruses have shown them to be ribonucleic acid containing viruses, with essential lipid and having compound helical symmetry with the diameter of the helix being in the neighbourhood of 180 a. because of these properties it is suggested that the virus should be considered a member of the myxovirus group. hog cholera virus is related to bovine viral diarrhea virus by means of a "soluble" antigen, and also posses ... | 1964 | 17649513 |
| soluble antigen of bovine viral diarrhea virus. i. intracellular synthesis, separation and characterization. | 1965 | 14269250 | |
| interference of bovine viral diarrhea virus by hog cholera virus in swine kidney cell cultures. | 1965 | 4286768 | |
| [contribution to mucosal disease--virus diarrhea-complex of cattle]. | 1965 | 5891089 | |
| comparative pathologic, immunologic, and clinical responses produced by selected agents of the bovine mucosal disease-virus diarrhea complex. | 1965 | 5892839 | |
| mixed infections or contaminations of bovine viral diarrhea virus with infectious bovine rhinotracheitis virus. | 1966 | 4287980 | |
| bovine viral diarrhea virus and escherichia coli in neonatal calf enteritis. | this study was initiated to determine the etiologic and pathogenic significance of an american strain of bovine viral diarrhea (bvd) virus (strain nadl-md) in enteritis of neonatal calves (calf scours). three colostrum-fed calves from dams exposed intravenously to bvd virus at 6, 16 and 25 days prepartum, respectively, had moderate diarrhea persisting until the eighth day of life. the bvd virus was isolated from all 3 calves and persisted up to 93 days in 1 calf, indicating either that bvd was t ... | 1968 | 4233834 |
| adaptation of bovine viral diarrhea virus to the madin-darby bovine kidney cell line. | 1968 | 4966759 | |
| characterization of bovine viral diarrhea viruses. i. determination of buoyant density. | 1968 | 4974542 | |
| characterization of bovine viral diarrhea viruses. ii. ultrafiltration properties of different strains after various treatments. | 1968 | 4974543 | |
| characterization of bovine viral diarrhea viruses. 3. partial purification by agar gel filtration. | 1968 | 4974544 | |
| distribution and persistence of mucosal disease virus in experimentally exposed calves. | 1968 | 5690779 | |
| homologous interference by an actively multiplying noncytopathic strain of bovine virus diarrhea-mucosal virus. | reduction in plaque size of cytopathic strains of bovine virus diarrhea-mucosal disease virus was determined to be a more sensitive indicator than number for detecting the interference induced by the noncytopathic strain of virus in cell cultures. | 1969 | 5813679 |
| bovine viral diarrhea virus-host cell interactions: adaptation, propagation, modification, and detection of virus in rabbits. | 1969 | 4896229 | |
| bovine viral diarrhea virus-host cell interactions: adaptation and growth of virus in cell lines. | 1969 | 4896230 | |
| detection of bovine viral diarrhea virus and antigen in tissues of experimentally infected calves by cell inoculation and fluorescent antibody techniques. | 1969 | 4898012 | |
| characterization of bovine viral diarrhea viruses. iv. sequential development of bvd viral antigen in cell cultures studied by immunofluorescence. | 1969 | 4900192 | |
| a study of bovine virus diarrhea mucosal disease virus by plaque technique. | bovine virus diarrhea-mucosal disease (bvd-md), nadl, strain formed 3-4 mm plaques on monolayers of bovine embryo kidney (bek), lung and testicular (bet) cell cultures on post inoculation day four. plaques were 1.5 mm on the post inoculation day five in lamb testicular cell cultures. neutral red incorporated in first overlay had inhibitory effect on plaque formation in these cell-virus systems. the study of effects of environmental variables on plaquing efficiency indicated that virus adsorption ... | 1969 | 4242771 |
| intranuclear inclusions in bovine embryo cell cultures infected with bovine virus diarrhoea-mucosal disease virus. | 1969 | 4304013 | |
| characterization of bovine viral diarrhea viruses. v. morphology of characteristic particles studied by electron microscopy. | 1969 | 4195624 | |
| electron optical studies of bovine viral diarrhea-mucosal disease virus (bvdv). | 1970 | 4192473 | |
| epidemiological observations on bovine viral diarrhea-mucosal disease virus-induced congenital cerebellar hypoplasia and ocular defects in calves. | 1970 | 4986633 | |
| [study by immuno-diffusion of several antigenic properties of bovine mucosal disease virus strains isolated in france]. | 1970 | 4996323 | |
| bovine viral diarrhea virus: neutralizing antibodies in a calf obtained by cesarean section from cow which was infected. | 1970 | 5414878 | |
| bovine viral diarrhea virus-host cell interactions: serotypes and their relationship to biotypes by cross neutralization. | 1971 | 5545462 | |
| [relationships between mucosal disease, virus diarrhea and hog cholera and their significance in veterinary practice]. | 1971 | 5000016 | |
| response of the bovine fetus to bovine viral diarrhea-mucosal disease virus. | 1971 | 5115543 | |
| bovine viral diarrhea-mucosal disease virus infection in pregnant cows. | 1971 | 5164965 | |
| isolation and identification of bovine viral diarrhea-mucosal disease virus (bvd-md virus) from an atypical case resembling malignant catarrhal fever (mcf). | 1971 | 5169166 | |
| a survey of sheep throughout australia for antibody to parainfluenza type 3 virus and to mucosal disease virus. | 1971 | 4328729 | |
| studies on bovine viral diarrhea-mucosal disease virus. ii. stability and some physico-chemical properties. | 1972 | 4116923 | |
| studies on bovine viral diarrhea-mucosal disease virus. i. cultural behaviour and antigenic relationship of some strains. | 1972 | 4404097 | |
| infection of sheep with a mucosal disease virus. | 1972 | 5013807 | |
| a cytopathogenic strain of bovine viral diarrhea-mucosal disease virus isolated from a bovine fetus. | 1972 | 5061945 | |
| buoyant density of bovine viral diarrhea virus. | 1972 | 5064488 | |
| effects of intrauterine inoculation of bovine viral diarrhea-mucosal disease virus on uterine tubes and uterus of nonpregnant cows. | 1973 | 4583643 | |
| abnormalities of in vitro lymphocyte responses during bovine viral diarrhea virus infection. | 1973 | 4707560 | |
| immunologic response of bovine fetus to bovine viral diarrhea virus. | 1973 | 4747033 | |
| virus induced congenital anomalies of the bovine fetus. i. cerebellar degeneration (hypoplasia), ocular lesions and fetal mummification following experimental infection with bovine viral diarrhea-mucosal disease virus. | 1973 | 4748881 | |
| the replication of bovine viral diarrhea-mucosal disease virus in bovine leukocytes in vitro. | 1973 | 4749260 | |
| separation of structural proteins of bovine viral diarrhea virus after degradation by different splitting techniques. brief report. | 1973 | 4796310 | |
| bovine virus diarrhoea-mucosal disease virus and border disease. | 1973 | 4807812 | |
| border disease-like syndrome in lambs: antibodies to hog cholera and bovine viral diarrhea viruses. | 1973 | 4201826 | |
| bovine viral diarrhea virus in swine: characteristics of virus recovered from naturally and experimentally infected swine. | a noncytopathogenic field strain of bovine viral diarrhea virus (bvdv) was isolated from an iowa farm brood sow and from her hysterectomy-derived, colostrum-deprived (hdcd) piglets. this field isolant was fully virulent for a neonatal calf. the nadl strain of bvdv was passaged through a series of hdcd piglets with no resultant loss of virulence for neonatal calves. most of the bvd viral isolants recovered from pigs had been changed from a cytopathogenic biotype to a noncytopathogenic biotype. ci ... | 1973 | 4265548 |
| bovine viral diarrhea virus in swine: neutralizing antibody in naturally and experimentally infected swine. | neutralizing antibodies against bovine viral diarrhea virus (bvdv) were detected in sera of iowa farm sows, their piglets derived by hysterectomy and in specific-pathogen-free (spf) pigs in a closed herd. no antibodies against bvdv were detected in sera of 134 fetal pigs from 67 sows in an iowa slaughter-house. neutralizing antibodies against bvdv or hog cholera virus, produced experimentally in spf pigs, were demonstrated to be due to different antigens rather than to a common antigen, although ... | 1973 | 4265558 |
| pathogenetic studies of infection of the bovine fetus with bovine viral diarrhea virus. i. cerebellar atrophy. | 1974 | 4377332 | |
| a hazy ('bull's eye') plaque variant of bovine viral diarrhea virus. | 1974 | 4212887 | |
| infection of pregnant ewes with mucosal disease virus of ovine origin. | 1974 | 4825997 | |
| bovine viral diarrhea virus: acquired resistance to acriflavine as marker of an attenuated strain. | 1974 | 4412238 | |
| comparison of low- and high-passage bovine turbinate cells for assay of bovine viral diarrhea virus. | 1974 | 4472511 | |
| evaluation of acetylethyleneimine-killed bovine viral diarrhea-mucosal disease virus (bvd) vaccine for prevention of bvd infection of the fetus. | 1975 | 220623 | |
| a study of immunologic relationships among serologically heterologous strains of bovine viral diarrhea virus by cross immunity tests. | three serologically heterologous strains of bovine viral diarrhea (bvd) virus were compared in reciprocal cross immunity tests in calves. each strain was inoculated into five calves. thirty-eight days later one calf in each group was reinoculated with homologous virus while the immunity of the remaining four was challenged with the serologically heterologous strains of virus, using two calves for each strain. of the 12 calves in the cross immunity tests, nine were refractory to immunity challeng ... | 1975 | 1112098 |
| propagation of bovine viral diarrhea viruses in bovine fetal lung cell cultures. | a procedure to prepare and maintain bovine fetal lung (bfl) cell cultures was established. these cell cultures grew abundantly and readily and were easy to handle. monolayers could be kept in satisfactory condition in maintenance medium for 14 days. the yield from the lungs of one fetus was 15 to 30 primary culture roux bottles, and 40,000 5th-generation test tubes. the bfl cells were satisfactorily kept at minus 70 c with the addition of dimethyl sulfoxide (dmso). when the bfl cell cultures wer ... | 1975 | 1168439 |
| characterization of bovine viral diarrhea virus rna. | rna extracted from isopycnically banded [3-h]uridine-labeled bovine viral diarrhea virus with sodium dodecyl sulfate was resolved into one major and two minor components by both sedimentation analysis and electrophoresis in polyacrylamide gels. the major rna component was estimated to have a 38s sedimentation coefficient. the minor rna components were estimated to have s values of 31 and 24. the approximate colecular weights were calculated to be 3.22 times 10-6 (38s), 2.09 times 10-6 (31s), and ... | 1975 | 1170338 |
| [epizootologic significance of grazing for mucosal disease/virus diarrhea in cattle]. | 1975 | 1209258 | |
| pathogenetic studies of infection of the bovine fetus with bovine viral diarrhea virus. ii. ocular lesions. | twenty-three susceptible pregnant heifers were inoculated with bovine viral diarrhea virus at 150 +/- 1 days of gestation. seven additional heifers were inoculated between 65 and 115 days of gestation. acute ocular lesions were seen in fetuses taken 17-21 days after inoculation of the dams at 150 days. by the fourth week, the acute lesions were beginning to resolve, and in newborn animals focal to total retinal atrophy was seen. the acute lesions were characterized by a mild to moderate retiniti ... | 1975 | 1229054 |
| structural proteins of bovine viral diarrhea virus. | a procedure for the purification of radioactively labeled bovine viral diarrhea virus was critically evaluated. purification of virus from artificial mixtures of unlabeled infected and labeled noninfected cells indicated that the extent of purification was approximately 100-fold with respect to host proteins. residual host proteins were found to contaminate the viral preparation even after extensive purification by differential and isopycnic zonal centrifugation. co-electrophoresis of 3h-labeled ... | 1975 | 1239230 |
| the reaction of pregnant ewes to inoculation with mucosal disease virus of bovine origin. | 1975 | 167056 | |
| [immunological correlations between 2 strains of mucosal disease virus diarrhea (short report]. | cross-neutralization tests of the c24v strain and the "kotschmar" strain provided evidence that the two strains are serological variants. independenthy of quantitative serological differences, these strains had a better immunizing action in calves against a virulent strain of md/vd virus. this virulent strain evidently formed a third serological variant, because when calves were infected with it, there was a decrease in the serological differences between antibodies. a practical conclusion is th ... | 1975 | 180926 |
| separation and properties of enterovirus and reovirus recovered from a fecal sample of calf with diarrhea. | in april, 1971, a disease with pyrexia and diarrhea as main symptoms broke out collectively among calves. fecal samples were collected from calves involved and inoculated into bovine kidney (bk) cell cultures. as a result, the diarrheal feces of one calf were suspected to contain two agents simultaneously. one agent (c-121 e strain) was isolated from the primary infected bk cell culture fluid by terminal dilution passages. it had been predominant in replication and shown a cytopathic effect whic ... | 1976 | 181679 |
| development of a cell culture line of bovine fetal endometrial cells. | monolayers of bovine fetal endometrial cells were established as primary culture cells within 1 to 2 weeks. after the 2nd passage, these cells were inoculated with bovine viral diarrhea virus. effects of the virus were observed each day with a light microscope. specific cytopathic effects consisting of degeneration and sloughing of the cells and a well-defined pattern of cytoplasmic vacuolation were observed at 5 days after inoculation. | 1976 | 183575 |
| fetal and adult bovine interferon production during bovine viral diarrhea virus infection. | levels of interferon in adult bovine serum and in fetal bovine serum and tissues were examined during the course of transplacental bovine viral diarrhea virus infection. the cows produced circulating interferon between 2 and 9 days after viral inoculation, with mean peak levels in the serum on day 4. interferon could be routinely detected in fetal tissues (e.g., thymus, spleen, and kidney) between days 4 and 21 after viral inoculation of the cows at 149 to 150 days of gestation (mid-second trime ... | 1976 | 184050 |
| a mucosal disease virus infection of the pregnant ewe as a cause of a border disease-like condition. | an experiment was designed to investigate whether a condition in australian sheep with clinical and pathological similarites to border disease was caused by the infection of the pregnant ewe with a mucosal disease virus (mdv). forty ewes, at 58 to 63 days after mating, were inoculated with material from lambs in which all, some or none of the tissues examined contained mdv. the clinical condition was observed only in lambs born to ewes inoculated with mdv-positive material and then only to ewes ... | 1976 | 184774 |
| a mucosal disease virus as a cause of abortion hairy birth coat and unthriftiness in sheep. 1. infiction of pregnant ewes and observations on aborted foetuses and lambs dying before one week of age. | a condition resembling border disease has been transmitted by the inoculation of pregnant ewes with material from affected lambs. forty-nine merino ewes, mated to merino rams 7 to 87 days previously, were inoculated with an homogenate of brain, spinal cord and spleen from affected lambs. mummified foetuses, abortions and stillbirths were observed, and lambs with hairy birth coats were born to ewes inoculated between days 12 to 70 of gestation. a mucosal disease virus (mdv), present in the origin ... | 1976 | 185999 |
| a mucosal disease virus as a cause of abortion, hairy birth coat and unthriftiness in sheep. 2. observations on lambs surviving for longer than seven days. | a condition in australian sheep resembling border disease was transmitted by the inoculation of pregnant ewes with material from affected lambs. this material contained mucosal disease virus (mdv). twenty-two lambs comprising 6 from uninoculated control ewes, together with 11 with hairy coats and 5 with normal coats from inoculated ewes, were observed from 7 to 182 days after birth. nine of the lambs from inoculated ewes died during the experiment from a variety of causes. glial cell abnormaliti ... | 1976 | 186000 |
| mechanism of protection from primary bovine viral diarrhea virus infection. i. the effects of dexamethasone. | a series of investigations was designed to study the role of cellular immunity and passive antibody in protecting neonatal calves from primary bovine viral diarrhea virus infection. administration of corticosteroids (dexamethasone) in doses capable of suppressing cellular immunity markedly potentiated systemic bovine viral diarrhea virus infection in calves which lacked bovine viral diarrhea passive neutralizing antibody. immunosuppressed calves did not form neutralizing antibody to bovine viral ... | 1976 | 187303 |
| natural infection of pigs with bovine viral diarrhea virus and its differential diagnosis from hog cholera. | natural infection of pigs with bovine viral diarrhea virus (bvdv) through contact with infected cattle has caused problems in diagnosing hog cholera (hc). low cross-reacting serum antibody titers against hc caused by bvdv infection were found in clinically normal pigs as well as those suspected of having hc. bovine viral diarrhea virus was isolated from specimen tissues and initially identified as hc virus (hcv), using the fluorescent antibody cell culture technique. additional cell cultures, as ... | 1976 | 187565 |
| in vitro transmission and propagation of the bovine leukemia virus in monolayer cell cultures. | this study demonstrates that the bovine leukemia virus (blv) can infect in vitro cells of human, simian, bovine, canine, caprine, ovine, and bat origin. cultures of these cells, cocultivated with blv-infected cells or inoculated with cell-free blv preparations, continuoously showed the presence of cells with the internal blv antigen as well as blv-induced syncytia. virus replication was abundant and increased with passage in bat lung cells and was moderate but constant in fetal canine thymus cel ... | 1976 | 61801 |
| studies on the natural occurrence of neutralizing antibodies against six strains of bovine viral diarrhea virus. | 1976 | 63200 | |
| differences in pathogenicity and antigenicity among hog cholera virus strains. | using antiserum against a particular strain of bovine viral diarrhea virus, the strains of hog cholera virus were divided into two groups, h and b, on the basis of the difference in the degree of neutralization. group h consisted of strains reacting poorly in neutralization, and group b consisted of strains reacting well with bovine viral diarrhea antiserum. most of the strains of group h induced a typical clinical form of hog cholera in experimentally infected pigs. inoculation of pigs with a s ... | 1977 | 203871 |
| transmission of a mucosal disease virus infection between sheep. | the transmission of mucosal disease virus (mdv) from infected ewes and their lambs to susceptible sheep was investigated. mdv was recovered from the amniotic fluid of an infected pregnant ewe and from the blood, nasal swabs and urine of hairy lambs. mdv infection was transmitted either at lambing, from infective foetal fluids or lambs, or later as a result of contact with a surviving with a hairy lamb and either aborted or gave birth to an infected hairy lamb. adult sheep and 12-months-old sheep ... | 1977 | 207251 |
| tween 80: a marker for differentiation of hog cholera and bovine viral diarrhea viruses. | markers for differentiating hog cholera and bovine viral diarrhea viruses were studied using tween 80, chloroform, trichlorotrifluoroethane and tri (n-butyl) phosphate. attenuated a and virulent ames strains of hog cholera virus were employed. moreover, the nadl pk-15 cell culture adopted strain and low cell culture passaged purdue strain of bovine viral diarrhea virus were used. these viruses were reacted with 2,500 micrograms/ml of tween 80 for one hour at 37 degrees c. when attenuated a and v ... | 1977 | 188531 |
| probable role of viruses in calfhood diseases. | bovine enteroviruses, bovine viral diarrhea virus, rotavirus (formerly called reovirus-like agent), coronavirus-like agent, bovine adenovirus, and bovine parainfluenza-3 virus have been isolated from calves suffering from neonatal disease. the experimental disease produced by these viruses is not necessarily severe or fatal, but under farm and ranch conditions, each probably serves as an added to mortality from neonatal disease. after initial losses following the introduction of a virus into a h ... | 1977 | 190279 |
| specific immune tolerance in an apparently healthy bull persistently infected with bovine viral diarrhea virus. | 1978 | 203564 | |
| duration of active and colostrum-derived passive antibodies to bovine viral diarrhea virus in calves. | duration of active and colostrum-derived passive antibodies to bovine viral diarrhea virus was studied in 14 calves. five calves born with actively induced antibodies to bovine viral diarrhea virus retained high titers during the year of observation. colostrum-derived antibodies to bovine viral diarrhea virus in nine calves declined at an expected rate for the first four to six months of age. however, titers of six of these calves increased at five to eight months of age and either remained cons ... | 1978 | 208738 |
| the use of polyethylene glycol in concentration and purification of several bovine viruses. | the polyethylene glycol (peg) precipitation method was used for the concentration and purification of eight bovine viruses. good results were obtained from four viruses, parainfluenza--3 virus, bovine enterovirus, bovine adenovirus, and bovine parvovirus. no satisfactory results of concentration were obtained from bovine reovirus, bovine viral diarrhea virus, and infectious bovine rhinotracheitis virus. the failure of concentration of the four viruses seems to be ascribed rather to the resuspend ... | 1978 | 211444 |
| isolation of viruses from cultures of bovine endometrial cells. | endometrial cells from the uteri of pregnant and nonpregnant cattle were cultured. the presence of one or both of two viruses, noncytopathic mucosal disease virus and bovine syncytial virus, was demonstrated in seven of 19 endometria investigated. it was necessary to subculture the cells an average of four times to detect the viral infections. difficulties were encountered in producing endometrial cell cultures from cows at term or near the end of term and also from older animals. the infections ... | 1978 | 213504 |
| the distribution of antibodies to border disease virus among sheep in england and wales. | within a sample of the sheep population of england and wales, 10.8 per cent of 3506 individuals had immunodiffusion test antibody to bovine viral diarrhoea mucosal disease virus antigen. there were marked differences between various geographical regions in the proportion of sheep with antibody, and border disease may be more common in some areas than disease records indicate. | 1978 | 214835 |
| serological studies of mucosal disease virus in england and wales. | a survey of the cattle population in england and wales showed that about 62 per cent of animals had neutralising (sn) antibody to bvd-md virus in their serum. fewer seropositive individuals were detected by immunodiffusion (53 per cent), and complement fixation (cf) tests (34 per cent). the prevalence of antibody was not affected by herd size, but some variation was found between various regions of the country, and the proportion of animals seropositive rose markedly with age. the immunodiffusio ... | 1978 | 203990 |
| maternal immunity to infectious bovine rhinotracheitis and bovine viral diarrhea viruses: duration and effect on vaccination in young calves. | the immune response to modified live-virus bovine viral diarrhea (bvd) vaccine and infectious bovine rhinotracheitis (ibr) vaccine was examined in calves that had received passive maternal antibodies to these viruses. blood serum samples from vaccinated and control (nonvaccinated) calves were examined for more than 1 year to determine the rate of decline of passive anti-bvd and anti-ibr antibodies and the effect that vaccination had on these antibody titers. the control calves lost their antibod ... | 1978 | 204233 |
| selected isolates of bovine viral diarrhea (bvd) virus propagated on bovine turbinate cells: virus titer and soluble antigen production as factors in immunogenicity of killed bvd virus. | soluble antigen production in a bovine turbinate cell line by 17 isolates of bovine viral diarrhea virus was studied. we showed that the quantity of soluble antigen produced may vary considerably between isolates. further, the isolate producing the greatest quantity of soluble antigen produced a higher antibody titer in calves than an isolate producing only half as much soluble antigen. | 1978 | 568462 |
| [case of md-vd in cattle]. | an enzootic is described of the classic form of virus diarrhea mucosal disease on a newly organized farm for heifers. the disease ran a sporadic course, mainly with intrauterine infections, while with the calves it was recorded as an enzootic with 100 per cent morbidity rate and 28 per cent mortality rate. the clinical picture was complicated--in some calves the disease started with fever, in other respiratory distrubances were observed, while in a third group diarrhea was prevailing. a detailed ... | 1978 | 741646 |
| [trials to obtain a hyperimmune serum against bovine mucosal disease-virus diarrhea]. | obtained are two types of hyperimmune sera against the virus of the mucous disease--viral diarrhea (md--vd) by means of subcutaneous and venous hyperimmunization of cattle with a live viral suspension: (a) a polyvariant hyperimmune serum, obtained by the use of four local and reference strains of the md--vd virus with a neutralization titre against the nadl strain of 1 : 1280. (b) monovariant hyperimmune serum, prepared by the use of a reference strain of the md--vd virus with a neutralization t ... | 1978 | 223277 |
| serological response of the bovine fetus to bovine viral diarrhea virus. | susceptible pregnant heifers were inoculated with bovine viral diarrhea virus at 150 days of gestation and earlier. fetuses were surgically collected at selected times after inoculation. serum immunoglobulins were quantitated, and the presence of specific antibodies was determined. in fetuses from heifers inoculated at 150 days, immunoglobulin m (igm) appeared approximately 2 weeks after inoculation and was followed in 7 days by igg1. later igg2 was detected in the sera of three fetuses. serum-n ... | 1979 | 225278 |
| border disease: persistant infection with the virus. | two genetically related sheep that produced border disease-affected lambs from successive pregnancies were identified. these sheep, and some of their progeny, were found to be persistently infected with a virus antigenically related to bovine virus diarrhoea/mucosal disease virus. only one of the sheep developed detectable serum antibody to the virus, and this animal only produced it 12 months after being detected as infected. the epidemiological significance of sheep persistently infected with ... | 1979 | 225856 |
| the indirect fluorescent antibody technique as a method for detecting antibodies in aborted fetuses. | in this investigation the indirect fluorescent antibody technique was used to titrate antibodies in bovine sera to parainfluenza 3, infectious bovine rhinotracheitis virus and bovine viral diarrhea virus. these results were compared to those determined on the same samples by hemagglutination inhibition for parainfluenza 3 virus and serum neutralization for bovine virus diarrhea and infectious bovine rhinotracheitis virus. the results of the serological methods agreed closely. the indirect fluore ... | 1979 | 226243 |
| depression of bovine monocyte chemotactic responses by bovine viral diarrhea virus. | incubation of bovine peripheral blood monocytes with bovine viral diarrhea virus (either singer or ny-1 strain) caused a consistent, statistically significant decrease in their random locomotion (no chemoattractant) and chemotaxis towards a chemotactic lymphokine. chemotaxis was determined by a modification of the boyden method. incubation of bovine viral diarrhea virus with mononuclear cells depressed chemotaxis by a mean of 56% (p less than 0.0005). heat-killed virus had no effect on monocyte ... | 1979 | 226479 |
| the prevalence of antibodies to bovine viral diarrhoea/mucosal disease virus in african wildlife. | 1979 | 228902 | |
| an immunodiffusion test for detection of bovine viral diarrhea virus antibodies in bovine serum. | an immunodiffusion test (idt) was developed for detecting bovine viral diarrhea virus antibodies in bovine serum. the antigen utilized in the idt was prepared from bovine viral diarrhea virus-infected monolayer cultures. results of the idt were obtained within 48 hours and correlated with the virus-neutralization test. | 1979 | 230770 |
| congenital cerebellar hypoplasia in newborn calves. | a sporadic outbreak of congential cerebellar ataxia (cca) was seen in calves. the abnormality of this disorder of the central nervous system characteristic was cerebellar hypoplasia, which was observed in eight calves. the cerebellum was almost completely absent in some of these calves and approximately one-fifth of the normal size in some others. six of the eight calves were also affected with hydrocephaly. the significant changes of the cerebellum were complete or partial destruction of the co ... | 1979 | 550073 |
| detection of three polypeptides in preparations of bovine viral diarrhoea virus. | radiolabelled bovine viral diarrhoea/mucosal disease virus (bvdv) strains nadl and oregon c24v were purified by different steps. following immunoprecipitation, electrophoresis in sds-polyacrylamide gels revealed three bvdv structural polypeptides with molecular weights of 57 (vp1), 44 (vp2), and 34 (vp3) kd. the two larger bvdv polypeptides vp1 and vp2 were found to be glycosylated (gp57, gp44). the data obtained on bvdv structural proteins demonstrate common features with hog cholera virus and ... | 1979 | 222243 |
| suppression of in vitro immunoglobulin biosynthesis in bovine spleen cells by bovine viral diarrhea virus. | 1979 | 222524 |