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some findings concerning a report on the cultivation of feline panleukopenia virus in cell culture. 196117421307
immunofluorescence of feline panleucopenia virus in cell culture: determination of immunological status of felines by serum neutralization.utilizing specific immunofluorescence as a viral indicator for a cell culture serum-neutralization system, the authors were able to demonstrate a relationship between specific antibody titer and susceptibility of felines to feline panleucopenia virus. this correlation was established by comparing prechallenge serum-neutralization titers to the clinical response of felines challenged with feline panleucopenia virus. the serological and clinical response of felines inoculated with commercial vacci ...196514281074
the preliminary use of attenuated feline panleukopenia virus to protect cats against panleukopenia and mink against virus enteritis. 19655893051
studies on cell culture adapted feline panleukopenia virus. virus neutralization & antigenic extinction. 19664954628
identity of feline ataxia virus with feline panleucopenia virus. 19674962202
congenital infections of cats and ferrets by feline panleukopenia virus manifested by cerebellar hypoplasia. 19674965699
feline viruses. iv. isolation and characterization of feline panleukopenia virus in tissue culture and comparison of cytopathogenicity with feline picornavirus, herpesvirus, and reovirus. 19704191787
enzyme histochemistry of the small intestine in germfree and specific-pathogen-free cats inoculated with feline infectious enteritis (feline panleukopenia) virus. 19704249951
enzyme histochemistry of lymphoid tissues in germfree cats inoculated with feline infectious enteritis (feline panleukopenia) virus. 19704249952
cerebellar ataxia and its congenital transmission in cats by feline panleukopenia virus. 19715103504
comments on cerebellar ataxia and its congenital transmission in cats by feline panleukopenia virus. 19715103505
the synaptic organization of the malformed cerebellum induced by perinatal infection with the feline panleukopenia virus (plv). ii. the purkinje cell and its afferents. 19715135012
the synaptic organization of the malformed cerebellum induced by perinatal infection with the feline panleukopenia virus (plv). i. elements forming the cerebellar glomeruli. 19715147778
immune carrier state of feline panleukopenia virus-infected cats. 19714928338
pathogenesis of feline panleukopenia virus in susceptible newborn kittens i. clinical signs, hematology, serology, and virology.inoculation of susceptible newborn kittens with a large dose of panleukopenia virus caused subclinical infection in 19 of 23 cases. all infected kittens developed severe and prolonged leukopenia. cell-free virus was present in the blood from 1 to 7 postinoculation days. the virus spread to all organs, regardless of the route of inoculation. the thymus, spleen, mesenteric lymph nodes, and the cerebellum were the most severely infected organs. kittens responded to virus infection by production of ...197116558063
pathogenesis of feline panleukopenia virus in susceptible newborn kittens ii. pathology and immunofluorescence.twenty-three susceptible newborn kittens were inoculated with feline panleukopenia virus on the day of birth and were sacrificed from 18 hr to 43 days postinoculation (dpi). macroscopic lesions included thymic atrophy in animals examined at 4 to 14 dpi and cerebellar hypoplasia and degeneration in animals examined at 22 to 43 dpi. clinical signs of ataxia were not observed in the four kittens with cerebellar lesions sacrificed at 22 to 43 days of age. intranuclear inclusions were present in a va ...197116558064
relationship of mink virus enteritis virus and feline panleukopenia virus: rapid onset of mink virus enteritis virus protection after feline panleukopenia virus infection. 19724673226
absence of an immune response after oral administration of attenuated feline panleukopenia virus.cats were orally vaccinated with attenuated feline panleukopenia virus to compare this route with parenteral immunization. cats receiving vaccine virus by mouth did not produce a systemic or local antibody response to the virus. intranasal and subcutaneous vaccination produced high levels of neutralizing antibodies and provided protection from challenge with virulent virus. the results suggest that virus does not initially infect the tissue of the oral pharynx or gastrointestinal tract as previo ...19734762109
some properties of feline panleukopenia virus. 19734128925
a study on in vitro isolation of feline panleukopaenia virus. 19734520222
a new vaccine strain of feline panleukopenia virus grown in ferret cell culture. 19744491924
studies on the growth of feline panleukopaenia virus in cell cultures.the growth of feline panleukopaenia virus was examined in relation to various cell growth curves of secondary feline kidney cells. in cell cultures with a high mitotic index, the manifestation of virus infection, expressed as percentage number of cells with inclusion bodies, was correspondingly high. in cultures with low mitotic index, the percentage number of cells with inclusion bodies was low. a cytopathic effect was seen by inoculation of virus with a titre of 10-3-5tcid-50/ml. this effect w ...1975168729
histopathology of feline panleukopenia in domestic cats.histopathological observations were carried out on 17 domestic cats naturally affected with feline panleukopenia. principal lesions were found in the intestine, bone marrow, and lymphoid organs. intestinal lesions were characterized by degenerative changes accompanied by the appearance of intranuclear inclusion bodies in the epithelial cells of the crypts. in contrast to the crypts, the villi were seldom involved. hypoplasia, parenchymal degeneration, and activation of the reticuloendothelial sy ...1975170544
feline panleukopenia in japan. ii. hemagglutinability of the isolated virus. 1975172687
studies on feline panleukopenia. i. isolation and properties of virus strains. 1975172688
retinal dysplasia due to feline panleukopenia virus infection. 19751184424
seasonality, natality and herd immunity in feline panleukopenia.feline panleukopenia (fpl) was diagnosed in 185 of 7043 feline admissions (2.63%) at a university veterinary hospital over an eight-year period. flp has a distinct seasonal pattern, occurring during july, august and september. seasonal peaks were noted in all the years studied. cats less than one year of age accounted for 70% of the total morbidity. the birth of felines in the united states also assumes a distinctly seasonal pattern. analysis of 47,786 purebred litters born during 1970-1972 reve ...1976174425
evaluation of 6-azauridine and 5-iododeoxyuridine in the treatment of experimental viral infections.the potential antiviral activity of 6-azauridine and 5-iododeoxyuridine was evaluated in a coordinated study at five institutions. experimental models in five species, the mouse, rabbit, swine, cat, and ferret, were established with use of 10 viruses: herpesvirus hominis types 1 and 2, murine cytomegalovirus, vaccinia virus, shope fibroma virus, transmissible gastroenteritis virus, swine influenza virus, feline viral rhinotracheitis virus, feline panleukopenia virus, and ferret distemper virus. ...1976180189
feline panleukopenia in japan. iii. propagation of the virus in cat kidney cell cultures. 1976181626
the parvoviruses. 1976181899
persistence of antibody to feline panleucopaenia induced by a modified live virus vaccine. 1976184348
fine structure of epithelial cells of lieberkühn's crypts in feline panleukopenia.electron microscopic observation was carried out on epithelial cells of lieberkühn's crypts of cats naturally affected with feline panleukopenia. the most important change was the replication of feline panleukopenia. the most important change was the replication of feline panleukopenia virus in the nucleus with associated alterations in the lining epithelial cells of the crypts. in these cells in the early stage of infection, virus particles 20 nm in average diameter were found either singly or ...1976189222
effect of feline panleukopenia virus infection on development of humoral and cellular immunity.cats were infected with feline panleukopenia virus (fplv) at various ages pre- and post-parturition. all fetuses infected at 35 days of gestation from one queen and a single fetus infected at 45 days of gestation from a second queen had a significant delay in time of skin allograft rejection. older fetuses and newborn kittens infected with fplv did not show this delay in rejection time. adult cats infected with fplv demonstrated a significant decrease in lymphocyte responsiveness to two t cell m ...1976782787
experimental feline panleucopenia in the conventional cat.coventional kittens, 12-27 weeks old, were inoculated with cell-cultured feline panleucopenia virus and killed sequentially between day 3 and day 24 after inoculation. all developed a non-fatal mild disease between days 2 and 9, characterized by lymphopenia, neutropenia, listlessness, depression and the development of neutralizing antibodies to the virus. small intestinal bacterial counts were reduced during the period of maximal clinical disease, presumably a result of decreased food intake. th ...1976936427
morphology of feline kidney culture cells infected with feline panleukopenia virus. 1977196223
[antigenic relationships between feline infectious peritonitis (fip) and transmissible gastroenteritis (tge) viruses in swine]. 1977200217
an attenuated mink enteritis virus and its use in a trivalent vaccine: studies on safety and antigenicity. 1977200331
feline panleukopaenia virus and mink enteritis virus. a serological study. 197766862
antigenic relationship of the feline infections peritonitis virus to coronaviruses of other species.utilizing the direct and indirect fluorescent antibody procedure, the antigenic relationship of the feline infectious peritonitis virus (fipv) to 7 other human and animal coronaviruses was studied. fipv was found to be closely related to transmissible gastroenteritis virus (tgev) of swine. transmissible gastroenteritis virus and fipv were in turn antigenically related to human coronavirus 229e (hcv-229e) and canine coronavirus (ccv). an interesting finding in the study was that the 8 coronavirus ...197881044
a case of partial cerebellar hypoplasia in a cat.a case of spontaneous ataxia accompanied by partial cerebellar hypoplasia in a two month old siamese kitten is described. the cause of cerebellar hypoplasia is unknown but the feline panleucopenia virus is number one to be suspected.1978662593
feline panleukopenia. iii. development of lesions in the lymphoid tissues.germfree and specific pathogen-free cats were inoculated with feline panleukopenia virus. cats were necropsied 2 to 6 days after inoculation and tissues from the thymus, lymph nodes and spleen taken for histological and immunofluorescence studies. necrosis of lymphoid cells in the thymic cortex began 3 days after inoculation and continued for 5 to 6 days after inoculation when the thymus was nearly depleted of lymphocytes. immunofluorescence studies showed the lesions to be caused by virus. ther ...1978685085
growth of an autonomously replicating parvovirus (feline panleukopenia): kinetics and morphogenesis. 1978208485
feline infectious peritonitis virus. ii. propagation in suckling mouse brain. 1978211754
pathogenesis of feline panleukopenia. 1978212405
studies on feline panleukopenia. ii. antigenicities of the virus. 1978212633
use of vaccines in exotic species. 1979222041
diagnostic exercise. cerebellar ataxia. 1979222957
the efficacy of two commercial feline rhinotracheitis-calicivirus-panleukopenia vaccines.the efficacy of two commercial feline vaccines was determined by challenging vaccinated and unvaccinated cats sequentially with a virulent feline calicivirus and rhinotracheitis virus. serological responses to these viruses as well as to panleuk openia virus were also measured. results show significant protection and satisfactory serological responses are conferred by both vaccines. one vaccine showed significant superiority in protection against feline viral rhinotracheitis.1979232426
immunisation against panleukopenia: early development of immunity.the time necessary to obtain the immunity of cats against panleukopenia has been studied by means of a modified live vaccine. this vaccine makes it possible to obtain a very early post-vaccinal immunity: the full immunity is reached 72 hr after the inoculation of the vaccine by the subcutaneous route. furthermore, we have demonstrated that a sensitive kitten can be admitted in a contaminated environment immediately after vaccination without showing any clinical evidence of the disease.1979233781
canine hemorrhagic enteritis: detection of viral particles by electron microscopy.at necropsy, several dogs which died showing symptoms of hemorrhagic diarrhea, had significant lesions of the mucosa that were found especially in the duodenum and upper part of the small bowel. study of ultrathin sections from the diseased mucosa revealed particles resembling parvoviruses in altered nuclei of cells of the intestinal crypts. electron microscopic examination of intestinal contents by negative staining has shown the presence of many viral particles which have a diameter of 24 nm a ...1979316320
lesions of spontaneous canine viral enteritis.spontaneous enteric disease characterized by hemorrhagic diarrhea and high mortality occurred in puppies from commercial kennels in three midwestern states. microscopic lesions resembling those of panleukopenia in cats were seen in the intestines. the predominant features were necrosis of crypt epithelium, collapse or dilation of crypt lumina and villous atrophy. viral particles morphologically resembling parvovirus were found in the feces by direct electron microscopy. the canine virus reacted ...1979505892
isolation and immunisation studies of a canine parco-like virus from dogs with haemorrhagic enteritis.a newly recognised canine parvo like virus was isolated from faeces of dogs with haemorrhagic enteritis. cell cultures from several species were susceptible to it. virus infected cells could be demonstrated by staining with fluorescent antibody reagents (prepared against canine virus or feline panleucopenia virus) or by haemagglutination with pig or rhesus monkey red blood cells. inhibition of haemagglutination by specific antiserum prepared in specific-pathogen-free beagles provided a convenien ...1979516347
a plaque assay for feline panleukopenia virus.plaque formation with representative strains of feline panleukopenia virus (fpv) has been obtained using a permanent line of feline kidney cells under agarose overlay. fpv-infected cells appear as white plaques after neutral red staining. plaque size is determined by the extent of cell division in the infected monolayer. fpv assay by the plaque procedure is rapid and gives infectivity titres which exceed those determined by the common inclusion body and immunofluorescent assays of fpv by a facto ...19806243343
virucidal disinfectants and feline viruses.thirty-five commonly used commercial disinfectants (disinfectants, antiseptics, sanitizers, and detergents) were evaluated for their virucidal activity against three feline viruses; feline viral rhinotracheitis virus (a herpesvirus), feline calicivirus, and feline panleukopenia virus (a parvovirus). disinfectants were diluted as recommended by the manufacturer and were reacted with virus for 10 minutes at room temperature. viruses were separated from disinfectants by gel filtration in special ce ...19806245610
feline rhinotracheitis-calici vaccine and feline rhinotracheitis-calici-panleukopenia vaccine: field evaluation for safety. 19806246668
hemagglutination by canine parvovirus: serologic studies and diagnostic applications.conditions for canine parvoviral hemagglutination (ha) and hemagglutination-inhibition (hi) reactions were defined. the ha phenomena were used to differentiate canine parvovirus (cpv) from feline panleukopenia virus (fpv), mink enteritis virus (mev), and minute virus of canines. serologic comparisons of the cpv, fpv, and mev by ha-hi and serum-neutralization tests indicated that cpv, fpv, and mev were antigenically similar but were different from minute virus of canines. diagnostic application o ...19806250432
origin of canine parvovirus. 19806254227
unusual sequelae to feline enteritis vaccination in a dog. 19806254228
canine parvovirus: safety and efficacy of attenuated feline panleucopenia vaccine. 19806254234
relationships of canine panleucopaenia (enteritis) and myocarditis paroviruses to feline panleucopaenia virus. 19806254483
vaccination of guide dogs. 19806255664
fpl vaccine and canine parvovirus. 19806255666
fpl vaccine and canine parvovirus. 19806255667
parvovirus infection. 19806258041
canine parvovirus vaccination. 19806258042
canine parvovirus infection in south american canids.canine parvovirus (cpv) infections occurred in 5 of 35 south american canids at the department of conservation (dc), a breeding facility of the national zoological park in front royal, va. the clinical signs were anorexia, lethargy, diarrhea, and vomiting. three of the affected canids survived and had high hemagglutination-inhibition titers to cpv in the recovery period. necropsy of the 2 that died revealed extensive necrosis of the intestinal mucosa; cpv particles were observed by electron micr ...19807451312
parvovirus infection in translocated raccoons.severe enteritis attributed to parvovirus infection was diagnosed in raccoons (procyon lotor) purchased from a commercial animal dealer for interstate translocation. intestinal lesions included edema, hyperemia, and focal mucosal necrosis. microscopically, intestinal villi were reduced markedly, and there was necrosis of the glandular crypts. intranuclear inclusions were seen in many crypt cells. a parvovirus that was infective for crandell feline kidney cells and primary canine kidney cells was ...19807451313
isolation of a virus closely related to feline panleukopenia virus from dogs with diarrhea. 19806158204
antigenic differences between canine parvovirus and feline panleucopenia virus. 19806266119
growth characteristics of feline panleukopenia virus in synchronized kitten kidney cells. 19816270441
prevalence of feline viral antibodies in random-source laboratory cats.over a period of 1973 to 1979, a serologic survey of virus infections was conducted on feline sera collected in four universities which located in different prefectures; obihiro, saitama, kanagawa and tokyo. a significant hemagglutination-inhibition (hi) antibody titer of 1 : 8 or higher to feline panleukopenia virus (fplv) was detected in 130 (58%) of the 226 sera used. no remarkable difference in the hi antibody prevalence in cats to fplv was recognized by years or localities. of a total of 18 ...19816274676
viral antibody studies of laboratory dogs with diarrheal disease.viral antibody studies were done on laboratory dogs in an epizootic of gastrointestinal disease. increased hemagglutination-inhibition antibody titers to a parvovirus (pv) antigenically related to feline panleukopenia virus were found in convalescent serum specimens of 78% (20/26) of the affected dogs and in 83% (5/6) of apparently healthy dogs. with one exception, all dogs tested had significant levels of hemagglutination-inhibition antibody to this pv. similar increased antibody titers were fo ...19816275746
antibody response to an inactivated vaccine for rhinotracheitis, caliciviral disease, and panleukopenia in nondomestic felids.the efficacy of an inactivated vaccine for the prevention of feline viral rhinotracheitis (fvr), feline caliciviral disease (fcvd), and feline panleukopenia (fpl) was tested in 27 nondomestic adult felids from 7 species. the vaccine was given im at the standard domestic cat dose in 19 animals and double this dose in 8 others. the animals were vaccinated either 1, 2, or 3 times. serum-neutralization (sn) antibodies to fvr (mean sn titer, 23) developed in all 15 animals that were previously serone ...19816276346
mink enteritis in japan. i. isolation and characterization of the causative virus and its pathogenicity in cat. 19816283219
mink enteritis in japan. ii. epidemiology of the disease. 19816283222
protozoan and viral infections of feral cats.identification of protozoan oocysts and serological tests were used to determine the prevalence of infections among 300 mainly adult feral cats in three different habitat types in south-eastern australia. oocysts of isospora rivolta and isospora felis were recovered from 3% and 4% respectively of 300 feral cat samples. haemagglutination inhibition antibody to toxoplasma gondii was detected in 20% of 75 cat sera tested. a high prevalence of specific antibody to feline panleukopaenia virus (79%) a ...19816280665
[detection of antibodies against the canine parvovirus in healthy dogs with indirect immunofluorescence technique (author's transl)]. 19816260454
[canine parvovirus infection in a group of beagles (author's transl)].an outbreak of canine parvovirus infection in a group of 26 beagles was described. the disease characterized by acute intestinal involvement was highly contagious but fatality was low (1/26). transient leukopenia was recorded in some animals. all the convalescent sera were positive in agar gel diffusion test using feline panleukopenia virus antigen. histopathological examination on fetal dog revealed regressive change associated with formation of amphophilic intranuclear inclusion bodies in the ...19817286068
necrotic colitis in two cats - a description of the lesions.the lesions in two cases of necrotic colitis in old cats are described. both had gross lesions of a necrotic, hemorrhagic colitis without gross lesions in the small intestine. histologically the lesions resembled those of feline panleukopenia virus infection, namely: necrosis and loss of crypt epithelium, dilation of crypts and lining of crypts by flattened epithelium, subsequent collapse of the lamina propria and hemorrhage from subepithelial capillaries. both grossly and histologically these l ...198217422154
successful experimental challenge of dogs with canine parvovirus-2.withholding food from dogs for 24 hours prior to, and for 48 hours following oral challenge with a gut mucosal homogenate of canine parvovirus-2, was a successful means of reproducing gastroenteric signs of canine parvovirus-2 infection. twenty-one of 24 dogs, which had previously received various vaccine preparations of mink enteritis virus or were unvaccinated, and which were starved at challenge, developed soft or liquid feces with large or without large clots of mucus. altered feces were mos ...19826280819
the failure of an inactivated mink enteritis virus vaccine in four preparations to provide protection to dogs against challenge with canine parvovirus-2.four experimental vaccine preparations comprising a strain of mink enteritis virus inactivated by either formalin or beta-propiolactone, and either adjuvanted or nonadjuvanted, failed to stimulate a consistent serum antibody response in 20 vaccinated dogs and failed to protect all but one of these dogs against oral challenge with canine parvovirus-2.19826280820
development of a vaccine incorporating killed virus of canine origin for the prevention of canine parvovirus infection.a parvovirus of canine origin, cultured in a feline kidney cell line, was inactivated with formalin. three pilot serials were produced and three forms of finished vaccine (nonadjuvanted, single adjuvanted and double adjuvanted) were tested in vaccination and challenge trials. a comparison was also made with two inactivated feline panleukopenia virus vaccines, one of which has official approval for use in dogs. the inactivated canine vaccine in nonadjuvanted, adjuvanted or double adjuvanted form ...19827039811
maternally derived immunity to canine parvovirus infection: transfer, decline, and interference with vaccination.antibody to canine parvovirus (cpv) was transferred from an immune bitch to her pups through the placenta and colostrum. colostral transfer accounted for approximately 90% of the maternally-derived cpv antibody. after suckling, pups and hemagglutination-inhibition titers that averaged 50% of their dam's titer. maternally derived cpv antibody declined with a half-life of 9.7 days. pups with hemagglutination-inhibition titers greater than or equal to 1:80 were immune to oronasal challenge with vir ...19827056660
epizootic of viral enteritis in dogs in thailand.an epizootic of enteritis occurred in dogs in thailand during 1979. observations were made on 44 dogs that had clinical signs of enteritis or had a recent history compatible with a clinical diagnosis of enteritis. eight of the 44 dogs died. gross and histopathologic examinations performed on these dogs revealed that the lesions were similar to those described for canine viral enteritis. antigens that agglutinated rhesus macaque rbc were detected in feces from 4 of 20 dogs. cytopathic effects wer ...19827149420
field evaluation of a canine parvovirus vaccination program, using feline origin modified live virus vaccine.antibody titers measured by hemagglutination inhibition testing were determined in previously vaccinated dogs at the time of booster vaccination and 2 weeks later. all vaccines consisted of modified live panleukopenia virus. the booster injection was administered approximately 6 months after the initial parvovirus vaccination series was given. fecal and serum specimens were collected immediately before and 2 weeks after administration of the booster vaccine for hemagglutination and hemagglutinat ...19826284689
raccoons are not susceptible to canine parvovirus. 19826290438
[immunoprophylaxis of parvovirosis in dogs (a review)]. 19826297146
evaluation of a killed feline panleukopenia virus vaccine against canine parvoviral enteritis in dogs.immunogenic potency of a killed feline panleukopenia virus vaccine against canine parvoviral enteritis in dogs was examined. the vaccine elicited hemagglutination-inhibition antibodies to canine parvovirus (cpv) in all of the 72 dogs which were vaccinated. the vaccine was protective in dogs against both experimentally induced and naturally occurring cpv-induced disease. by statistical analysis, 4 weeks was found to be the optimal spacing between 2 vaccinal doses resulting in hemagglutination-inh ...19826299140
dog response to inactivated canine parvovirus and feline panleukopenia virus vaccines.inactivated canine parvovirus (cpv) and inactivated feline panleukopenia virus (fpv) vaccines were evaluated in dogs. maximal serologic response occurred within 1-2 weeks after vaccination. antibody titers then declined rapidly to low levels that persisted at least 20 weeks. immunity to cpv, defined as complete resistance to infection, was correlated with serum antibody titer and did not persist longer than 6 weeks after vaccination with inactivated virus. however, protection against generalized ...19826279359
antigenic relationships between canine parvovirus type 2, feline panleukopenia virus and mink enteritis virus using conventional antisera and monoclonal antibodies.the antigenic relationships between three similar parvoviruses, canine parvovirus type 2 (cpv), feline panleukopenia virus (fpv) and mink enteritis virus (mev) were investigated. antisera against all 3 viruses and monoclonal antibodies (mab) to cpv were prepared and the viruses compared using several serological methods. when conventional sera were used in the hemagglutination-inhibition and agar gel precipitin (agp) tests there were no differences between the cpv viral isolates studied, but ant ...19826180709
canine parvovirus: relationship to wild-type and vaccine strains of feline panleukopenia virus and mink enteritis virus.canine parvovirus (cpv), feline panleukopenia virus (fplv) and mink enteritis virus (mev) were compared serologically, by determination of their host range in cell cultures, as well as by restriction enzyme analysis. maps of the virus genomes were established using seven different restriction enzymes cutting at a total of 56 sites. mev and fplv gave maps which were identical except for one restriction site. the map of cpv is closely related to those of fplv/mev since their dnas share about 80% o ...19826181186
antigenic structure and variation of canine parvovirus type-2, feline panleukopenia virus, and mink enteritis virus.the antigenic structure and variation of canine parvovirus type-2 (cpv), feline panleukopenia virus (fpv), mink enteritis virus (mev), and a closely related virus of raccoons (rpv) was investigated using a panel of 13 monoclonal antibodies (mab) formed against cpv and 8 mab formed against fpv. each mab both neutralized and inhibited the hemagglutination of the homologous virus. all mab tested immunoprecipitated the two capsid proteins. five mab were specific for the cpv isolates and one reacted ...19836194613
use of modified live feline panleukopenia virus vaccine to immunize dogs against canine parvovirus.modified live feline panleukopenia virus (fplv) vaccine protected dogs against canine parvovirus (cpv) infection. however, unlike the long-lived (greater than or equal to 20-month) immunity engendered by cpv infection, the response of dogs to living fplv was variable. doses of fplv (snow leopard strain) in excess of 10(5.7) tcid50 were necessary for uniform immunization; smaller inocula resulted in decreased success rates. the duration of immunity, as measured by the persistence of hemagglutinat ...19836299142
immunofluorescence for feline infectious peritonitis virus with trypsin-treated paraffin sections. 19836306316
response of mink, skunk, red fox and raccoon to inoculation with mink virus enteritis, feline panleukopenia and canine parvovirus and prevalence of antibody to parvovirus in wild carnivores in ontario.mink virus enteritis, feline panleukopenia and canine parvovirus-2 were inoculated separately into groups of raccoon, mink, red fox and striped skunk. raccoons were highly susceptible to mink virus enteritis and feline panleukopenia, with animals developing clinical illness, and several dying within six to ten days of inoculation with lesions typical of parvovirus infection. both viruses were shed in high titre in the feces of infected raccoons, and high antibody titres were stimulated. raccoons ...19836309349
molecular cloning of the aleutian disease virus genome: expression of aleutian disease virus antigens by a recombinant plasmid.three nonoverlapping segments representing approximately 80% of the 4.8-kilobase pair aleutian disease virus (adv-g) duplex genome were molecularly cloned into either bacteriophage m13mp9 (m13bm2 = 0.07 to 0.15 map unit; m13bm1 = 0.15 to 0.54 map unit) or plasmid puc8 (pbm1 = 0.54 to 0.88 map units). in addition the 0.54- to 0.88-map unit segment of a danish isolate of adv (dk adv) was also cloned into puc8 (pbm2). the recombinant plasmids pbm1 and pbm2 induced expression of several polypeptides ...19836313959
comparison of the viral proteins of canine parvovirus-2, mink enteritis virus and feline panleukopenia virus.canine parvovirus-2 (cpv-2), mink enteritis virus (mev) and feline panleukopenia virus (fpv) were produced using identical cell culture and purification techniques. the distributions of the haemagglutinating activity of the three different parvoviruses in a cscl gradient were similar with haemagglutinating peaks identified at 1.48-1.49, 1.42, 1.36 and 1.30-1.31 g cm-3. the number and distribution of the viral proteins and the equivalent protein molecular weights are similar for all three viruses ...19836316627
macrotiter assay for coronavirus-neutralizing activity in cats using a canine continuous cell line (a-72).a heterologous neutralization assay for feline infectious peritonitis virus serology was developed using a single continuous cell line of canine origin, a-72, which is susceptible to cytopathic infection with both transmissible gastroenteritis virus of pigs and canine coronavirus. of several coronavirus isolates tested, the 1-71 isolate of canine coronavirus demonstrated the most effective neutralization by serum and body fluids of cats with histopathologically confirmed feline infectious perito ...19836319813
[serological immune response following vaccination with inactivated parvovirus vaccines in the dog]. 19836320363
experimental infection of feline panleukopenia virus in specific pathogen-free cats. 19836865168
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