Publications

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natural infection of north african gundi (ctenodactylus gundi) by leishmania tropica in the focus of cutaneous leishmaniasis, southeast tunisia.north african gundis (ctenodactylus gundi) were trapped in the leishmania (l.) tropica focus of cutaneous leishmaniasis, situated in southeast tunisia and evaluated for leishmania infection by real-time kinetoplast dna polymerase chain reaction (pcr). species identification was performed by internal transcribed spacer one (its1)-pcr-restriction fragment length polymorphism (rflp) and high-resolution melting (hrm) analysis of the 7sl rna gene. real-time pcr on blood was positive in 6 of 13 (46.2% ...022665601
[mixed sero-epidemiologic study of arbovirus-arenavirus in the small mammals of tunisia].blood samples of 156 small mammals caught in tunisia in 1976 and 1977 were examined for the presence of antibodies to some arboviruses and arena-viruses. haemagglutination-inhibiting antibodies against west nile virus were detected in 19.8 0/0 of examined sera, mainly from mus sp., rattus rattus, eliomys tunetae in the northern part of the country and from ctenodactylus gundi and pipistrellus kuhli in the south. in addition, antibodies against uukuniemi and bhanja were found in 3.2 0/0 and 4.5 0 ...1977615674
eimeria gundii n. sp. (protozoa: eimeriidae) from tunisian gundi (ctenodactylus gundi). 1978677725
renal function and concentrating ability in a desert rodent: the gundi (ctenodactylus vali).clearance and cortical micropuncture experiments were carried out on non diuretic gundis. in this species, the kidney has a long and well developed papilla but, unlike other desert rodents, the vascular organization of the outer medulla is very simple. after withdrawal of water supply for either 24 h or 3 days before the experiments, the urine osmolality was only 1,361 +/- 57, n = 9, before and 1,136 +/- 89 mosmol . kg-1 during anesthesia. the gfr per 100 g b.w.(0.450 ml . min-1) is lower than i ...19817195562
[not available].calls of ctenodactylus gundi living in semi-natural conditions in our laboratory were recorded during various interactions : sexual, agonistic, maternal. the physical characteristics of the sounds lead us to describe five major structural groups and eleven vocal types. two of them were recorded only in young animals. intermediate calls and some complex sequences formed by association of two vocal types were observed. when emitting sounds, adult gundis can produce eight vocal sequences. in two of ...198524896453
comparative anatomical study of the carotid circulation in gundis, with implications for their evolutionary history.the carotid circulation pattern in gundis (ctenodactylidae) is examined and compared with that of typical members of the classical rodent suborders. on this basis their probable phylogenetic relationships and systematic position are discussed. together with other recent investigations, the unique pattern of cephalic arterial supply emphasizes the isolated position of the ctenodactylids.19873825485
les sequences de remplacement chez ctenodactylus gundi: competition ou cooperation?ctenodactylus gundi, a colonial rodent inhabiting saharian atlas, is often seen standing at the top of the rocks. at more or less regular intervals, another conspecific is taking the place of the "resident" animal. this relief impues only amicable reliationships and is to be considered as a kind of cooperation. the function of the resident, as a specific element against predation, is discussed.198924897670
the primary structures of gundi (ctenodactylus gundi, rodentia) hemoglobin and myoglobin.the primary structures of the alpha- and beta-chains of hemoglobin and myoglobin from the gundi (ctenodactylus gundi, rodentia) are presented. the sequences were determined after enzymatic and chemical cleavages of the polypeptide chains and by sequencing of the peptides mainly by automated sequence analysis. the sequences of gundi hemoglobin chains and of myoglobin are compared with those of other rodents.19902085415
the biochemical phylogeny of guinea-pigs and gundis, and the paraphyly of the order rodentia.1. molecular data indicate that caviomorphs (guinea-pig-like rodents) and myomorphs (rat-like rodents) are not monophyletic. 2. rather, the evolutionary lineage leading to the guinea-pig may have branched off prior to the divergence among myomorphs, lagomorphs, primates, chiropterans, artiodactyls, and carnivores. 3. thus, the guinea-pig lineage probably represents an ancient eutherian lineage, and should be conferred an independent ordinal status. 4. the gundis (ctenodactylidae) also seem to ha ...19921611868
the molecular taxonomy and evolution of the guinea pig.on the basis of 18 protein sequences totaling 2,413 aligned amino acid sites, it is suggested that the guinea pigs and the myomorphs (rat-like rodents) are not monophyletic. rather, the evolutionary lineage leading to the guinea pig seems to have branched off prior to the divergence among myomorphs, lagomorphs, primates, chiropterans, artiodactyls, and carnivores. it is suggested therefore that the caviomorpha (guinea pig-like rodents) and possibly the hystricomorpha (porcupine-like rodents) sho ...19921624762
comparative histological and ultrastructural studies of the harderian gland of rodents.the harderian glands of six rodents (the wistar rat, the gerbils psammomys obesus, gerbillus gerbillus, meriones crassus, and meriones lybicus, and the gundi, ctenodactylus vali) were investigated by means of light and transmission electron microscopy. in rodents, the harderian gland consists of branching tubules, lined by a single layer of epithelial cells and possessing myoepithelial cells within their basal lamina. the harderian gland contains porphyrins, stored as intraluminal masses. the gl ...19969156607
variance of molecular datings, evolution of rodents and the phylogenetic affinities between ctenodactylidae and hystricognathi.the von willebrand factor (vwf) gene has been used to understand the origin and timing of rodentia evolution in the context of placental phylogeny vwf exon 28 sequences of 15 rodent families and eight non-rodent eutherian clades are analysed with two different molecular dating methods (uniform clock on a linearized tree; quartet dating). three main conclusions are drawn from the study of this nuclear exon. first, ctenodactylidae (gundis) and hystricognathi (e.g. porcupines, guinea-pigs, chinchil ...200010722222
molecular evolution of mammalian ribonucleases 1.there have been many studies on the chemistry of mammalian pancreatic ribonucleases (ribonucleases 1), but the functional biology of this family of homologous proteins is still largely unknown. many studies have been performed on the molecular evolution and properties of this enzyme from species belonging to a large number of mammalian taxa, including paralogous gene products resulting from recent gene duplications. novel ribonuclease 1 sequences were determined for three rodent species (gundi, ...200312742750
biology and epidemiology of toxoplasma gondii in man and animals.toxoplasma gondii is a coccidian parasite which utilizes felids as definitive hosts, and which has an unusually wide intermediate host range. the parasite was initially described by nicolle and manceaux in 1908 from the rodent, ctenodactylus gundi. infection with t. gondii is one of the most common parasitic infections of man and other warm-blooded animals. it has been found worldwide from alaska to australia. nearly one-third of humanity has been exposed to this parasite; serologic surveys indi ...200516164008
toxoplasma: the next 100years.it has been 100 years since toxoplasma gondii was initially described in tunis by nicolle and manceaux (1908) in the tissues of the gundi (ctenodoactylus gundi) and in brazil by splendore (1908) in the tissues of a rabbit. t. gondii is a ubiquitous, apicomplexan parasite of warm-blooded animals that can cause several clinical syndromes including encephalitis, chorioretinitis and congenital infection. due to the extensive repertoire of applicable experimental techniques available for this pathoge ...200818672085
a comparison of techniques for assessing dispersal behaviour in gundis: revealing dispersal patterns in the absence of observed dispersal behaviour.knowledge of the dispersal status of group members is important to understanding how sociality may have evolved within a species. i assessed the effectiveness of four techniques for elucidating dispersal behaviour in a rock-dwelling rodent (ctenodactylus gundi) with small group sizes (2-10 animals): genetic parentage assignment, haplotype data and kinship analyses, assignment testing, and f-statistics. the first two methods provided the greatest insight into gundi dispersal behaviour. assignment ...200819160481
evolution of the interhaemal barrier in the placenta of rodents.a recent phylogenetic analysis achieved good resolution between the 5 suborders of rodent. as a novel finding it suggested a basal split that gave rise to a monophyletic group comprising hystricomorpha and sciuromorpha. we asked whether the new tree could cast light on the evolution of the interhaemal barrier in rodents where at least seven variants have been described. to supplement existing data we first examined the placenta of the common gundi, ctenodactylus gundi. it was shown to be haemoch ...200919692122
toxoplasmosis: a history of clinical observations.it has been 100 years since toxoplasma gondii was initially described in tunis by nicolle and manceaux (1908) in the tissues of the gundi (ctenodoactylus gundi) and in brazil by splendore (1908) in the tissues of a rabbit. toxoplasma gondii is a ubiquitous, apicomplexan parasite of warm-blooded animals that can cause several clinical syndromes including encephalitis, chorioretinitis, congenital infection and neonatal mortality. fifteen years after the description of t. gondii by nicolle and manc ...200919217908
toxoplasma gondii proteomics.toxoplasma gondii is a ubiquitous, apicomplexan parasite that, in humans, can cause several clinical syndromes, including encephalitis, chorioretinitis and congenital infection. t. gondii was described a little over 100 years ago in the tissues of the gundi (ctenodoactylus gundi). there are a large number of applicable experimental techniques available for this pathogen and it has become a model organism for the study of intracellular pathogens. with the completion of the genomes for a type i (g ...200919489701
phlebotomus sergenti (parrot, 1917) identified as leishmania killicki host in gharda+»a, south algeria.since 2005, an outbreak of human cutaneous leishmaniasis (cl) in gharda+»a, south algeria, was studied and one output of these investigations was the identification of two leishmania species, leishmania major and leishmania killicki, as the cl causative agents. in the present study, we were curious to focus on sand fly fauna present in this area and detection of leishmania-positive sand fly females. sand flies (3717) were collected during two seasons using sticky papers and cdc light traps in ur ...201121382502
habitats of the sandfly vectors of leishmania tropica and l. major in a mixed focus of cutaneous leishmaniasis in southeast tunisia.from 2009 to 2010, 3129 sandflies were caught in cdc light traps placed in various habitats in ghomrassen, tataouine governorate, southeast tunisia, a mixed focus of human cutaneous leishmaniasis caused by leishmania tropica and leishmania major. species diversity was quantified in anthropogenic, semi-anthropogenic and semi-natural locations. sandflies were identified according to morphological characters and also by the comparative sequence analysis of a fragment of the mitochondrial cytochrome ...201121605538
first detection of leishmania killicki (kinetoplastida, trypanosomatidae) in ctenodactylus gundi (rodentia, ctenodactylidae), a possible reservoir of human cutaneous leishmaniasis in tunisia.abstract:201121834996
diversification and biogeography of the neotropical caviomorph lineage octodontoidea (rodentia: hystricognathi).the rodent superfamily octodontoidea comprises 6 families, 38 genera, and 193 living species of spiny rats, tuco-tucos, degus, hutias, and their relatives. all are endemic to the neotropical region where they represent roughly three-quarters of extant caviomorphs. although caviomorph monophyly is well established and phylogenetic hypotheses exist for several families, understanding of octodontoid relationships is clouded by sparse taxon sampling and single-gene analyses. we examined sequence var ...201222327013
afrojoyeuxia gen. n. and hunkeleriella gen. n., two new genera of cestodes (cyclophyllidea: anoplocephalidae) from african rodents.based on the study of type material, two new genera of cestodes (cyclophyllidea: anoplocephalidae) are proposed for paranoplocephala lüihe, 1910 sensu lato species from african rodents. afrojoyeuxia gen. n., proposed for a. gundii (joyeux, 1923) comb. n. from ctenodactylus gundi (rothmann) (hystricomorpha: ctenodactylidae), is characterized by a high length/width ratio of mature proglottids, longitudinally extensive testicular field positioned anterior to the female glands, an ovoid or subspheri ...201324471290
comparison of leishmania killicki (syn. l. tropica) and leishmania tropica population structure in maghreb by microsatellite typing.leishmania (l.) killicki (syn. l. tropica), which causes cutaneous leishmaniasis in maghreb, was recently described in this region and identified as a subpopulation of l. tropica. the present genetic analysis was conducted to explore the spatio-temporal distribution of l. killicki (syn. l. tropica) and its transmission dynamics. to better understand the evolution of this parasite, its population structure was then compared with that of l. tropica populations from morocco. in total 198 samples in ...201526645812
first miocene rodent from lebanon provides the 'missing link' between asian and african gundis (rodentia: ctenodactylidae).ctenodactylinae (gundis) is a clade of rodents that experienced, in miocene time, their greatest diversification and widest distribution. they expanded from the far east, their area of origin, to africa, which they entered from what would become the arabian peninsula. questions concerning the origin of african ctenodactylinae persist essentially because of a poor fossil record from the miocene of afro-arabia. however, recent excavations in the late miocene of lebanon have yielded a key taxon for ...201526250050
a transitional gundi (rodentia: ctenodactylidae) from the miocene of israel.we describe a new species of gundi (rodentia: ctenodactylidae: ctenodactylinae), sayimys negevensis, on the basis of cheek teeth from the early miocene of the rotem basin, southern israel. the rotem ctenodactylid differs from all known ctenodactylid species, including sayimys intermedius, which was first described from the middle miocene of saudi arabia. instead, it most resembles sayimys baskini from the early miocene of pakistan in characters of the m1-2 (e.g., the mesoflexid shorter than the ...201627049960
diversification rates in ctenodactylidae (rodentia, mammalia) from mongolia.gundis, or comb rats, are rodents of the family ctenodactylidae. extant gundis are restricted to africa and represent a vestige of the diversity that the ctenodactylids attained at both palaeoecological and palaeobiogeographical levels. here, we present an updated review of the ctenodactylidae from the valley of lakes, mongolia, based on the study of large collections now available. we have recognised 13 valid species of ctenodactylids grouped into five genera: karakoromys, huangomys, tataromys, ...201728408947
natural infection of ctenodactylus gundi by leishmania major in tunisia.incriminating new rodent species, as reservoir hosts of leishmania parasites is crucial for understanding the transmission cycle of cutaneous leishmaniasis in tunisia. ctenodactylus (c.) gundi was previously described as extremely abundant in all tunisian leishmania (l.) tropica foci in south tunisia besides its presence in l. major endemic area. the aim of this study was to detect leishmania species parasites among c. gundi in two endemic regions in tunisia: sidi bouzid and tataouine. total dna ...201828963065
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