Publications

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evolution of the major histocompatibility complex: a hundred-fold amplification of mhc class i genes in the african pigmy mouse nannomys setulosus.the genome of the african murine rodent nannomys setulosus was found to harbor several thousand major histocompatibility complex (mhc) class i genes instead of the 30-40 genes found in conventional laboratory mice, which are mostly of mus musculus domesticus origin. other genes of n. setulosus, either functionally or physically linked to class i genes, are not amplified. amplified genes derive from as few as three ancestors and amplification has likely occurred after the divergence of the two na ...19921428009
identification of ebola virus sequences present as rna or dna in organs of terrestrial small mammals of the central african republic.the life cycle of the ebola (ebo) virus remains enigmatic. we tested for ebo virus in the organs of 242 small mammals captured during ecological studies in the central african republic. ebo virus glycoprotein or polymerase gene sequences were detected by reverse transcription pcr in rna extracts of the organs of seven animals and by pcr in dna extract of one animal. neither live virus nor virus antigen was detected in any organ sample. direct sequencing of amplicons identified the virus as being ...199910580275
novel arenavirus sequences in hylomyscus sp. and mus (nannomys) setulosus from c+¦te d'ivoire: implications for evolution of arenaviruses in africa.this study aimed to identify new arenaviruses and gather insights in the evolution of arenaviruses in africa. during 2003 through 2005, 1,228 small mammals representing 14 different genera were trapped in 9 villages in south, east, and middle west of c+¦te d'ivoire. specimens were screened by pan-old world arenavirus rt-pcrs targeting s and l rna segments as well as immunofluorescence assay. sequences of two novel tentative species of the family arenaviridae, menekre and gbagroube virus, were de ...201121695269
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