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an eyeless mutant in drosophila hydei. 192217245984
five autosomal mutants in drosophila hydei. 192817246541
iso-alleles at the bobbed locus in drosophila hydei populations. 194417247136
nutritional requirements of drosophila hydei. 194521010489
[inhibition of mitosis and polyploidy atrributable to a lethal factor in drosophila hydei]. 195213067189
[radiation sensitivity in early embryonal stages of drosophila hydei sturtevant in comparison to drosophila melanogaster meigen]. 195713519312
arsenates: effect on fecundity in some diptera.four species of adult diptera, rhagoletis pomonella (walsh), drosophila melanogaster mg., drosophila hydei sturt., and musca domestica l. showed varying degrees of reduced fecundity when sublethal doses of arsenic were included in their food. the possible influence of the frequent use of arsenicals on arthropod populations is discussed.196317829544
chromosomal differentiations of the lampbrush type formed by the y chromosome in drosophila hydei and drosophila neohydei.the nuclei of growing spermatocytes in drosophila hydei and d. neohydei are characterized by the appearance of phase-specific, paired, loop-shaped structures thought to be similar to the loops in lampbrush chromosomes of amphibian oocytes. in x/o-males of d. hydei spermatogenesis is completely blocked before the first maturation division. no spermatozoa are formed in such testes. in the nuclei of x/o-spermatocytes, paired loop formations are absent. this shows the dependence of these chromosomal ...196313954225
submicroscopic structure of drosophila hydei salivary gland cells. 196313970551
asynapsis in the salivary gland chromosomes of drosophila hydei. 196313970550
salivary gland function and chromosomal puffing patterns in drosophila hydei. 19655833949
the induction of changes in chromosomal activity in different polytene types of cell in drosophila hydei. 19655840021
the effect of x-rays on the functional structures of the y chromosome in spermatocytes of drosophila hydei. 196514283627
[structure differentiations in the y-chromosome of drosophila hydei and their relations to gene activities. ii. effect of rna synthesis inhibition by actinomycin]. 196514286190
[structure-differentiation in the y-chromosome of drosophila hydei and its relation to gene activity. 3. sequence and localization of the loop organizers]. 196514340397
experimental puffs in salivary gland chromosomes of drosophila hydei. 196514282196
an autoradiographic study of rna synthesis in isolated salivary glands of drosophila hydei. ii. interferometric studies. 196514294957
an autoradiographic study of rna synthesis in isolated salivary glands of drosophila hydei i. autoradiographic studies. 196514294956
pteridines and gene homologies in the eye color mutants of drosophila hydei and drosophila melanogaster. 196517248279
[the localization of carcinogenic hydrocarbons in the salivary glands of drosophila hydei]. 19665916587
puff induction in larval salivary gland chromosomes of drosophila hydei sturtevant. 19665939566
distribution of dna in heterochromatin and euchromatin of polytene nuclei of drosophila hydei. 19676077528
complementation of genetic activity in translocated fragmentsof the y chromosome in drosophila hydei. 19676035600
larval moulting cycle and dna synthesis in drosophila hydei salivary glands. 19676029544
the hormone ecdysone as effector of specific changes in the pattern of gene activities of drosophila hydei. 19676077846
ribonucleic acid synthesis of the y-chromosome of drosophila hydei. 19685760638
mass preparation of nuclei from the larval salivary glands of drosophila hydei.a method has been developed for isolating gram quantities of salivary glands from late third instar larvae of drosophila hydei. the isolated glands have a normal appearance and incorporate rna and dna precursors normally. nuclei can be isolated from these glands in 90% yield with the use of detergents. these nuclei contain morphologically normal giant polytene chromosomes.19685664209
variations of nucleic acid content in the salivary glands of drosophila hydei during late larval development. 19685637633
the function of the lampbrush loops formed by the y chromosome of drosophila hydei in spermatocyte nuclei. 19685713536
the replicative organization of dna in polytene chromosomes of drosophila hydei. 19684181535
[concentration of tritium-labelled ecdysone in the cell nuclei of the salivary glands of drosophila hydei]. 19695404075
strain differences in egg structure in drosophila hydei. 19695392211
structural and functional properties of polytene nuclei isolated from salivary glands of drosophila hydei.salivary gland nuclei of drosophila hydei, isolated by a modification of the procedure described by boyd et al. (9), retain their normal morphology during the isolation and subsequent incubation procedure. rna synthesis was studied in isolated nuclei by biochemical and cytological techniques. in radioautographs 70% of the nuclei displayed a distribution of labeled rna over the nuclear constituents similar to the distribution obtained after in vivo incorporation of radioactive precursor. chromoso ...19695783875
local protein accumulation during gene activation. i. quantitative measurements on dye binding capacity at subsequent stages of puff formation in drosophila hydei. 19704104059
time sequence in the expression of various developmental characters induced by ecdysterone in drosophila hydei. 19704248971
deoxyribonucleases of the organs of drosophila hydei at the onset of metamorphosis. 19705456434
an analysis of white-mottled mutants in drosophila hydei, with observations on x-y exchanges in the male. 19705512359
genetic function correlated with unfolding of lampbrush loops by the y chromosome in spermatocytes of drosophila hydei. 19705481022
[abnormal-abdomen in drosophila hydei]. 19705480760
characterization of an alkaline active deoxyribonuclease from the prepupal salivary gland of drosophila hydei. 19705453522
characterization of an acid active deoxyribonuclease from the larval salivary gland of drosophila hydei. 19704989255
sequence diversity of polytene chromosome dna from drosophila hydei. 19715133116
reduced polyteny of ribosomal rna cistrons in giant chromosomes of drosophila hydei. 19715286999
induced accumulation of nonhistone proteins in polytene nuclei of drosophila hydei. 19715098869
chromosomal basis of dosage compensation in drosophila. v. puffwise analysis of gene activity in the x-chromosome of male and female drosophila hydei. 19715158950
the action of the notch locus in drosophila hydei. 19715112156
x-y exchanges in males of drosophila hydei carrying the wmco duplication. 19715112155
highly repetitive dna sequences in the genome of drosophila hydei. ii. occurrence in polytene tissues. 19724635992
highly repetitive dna sequences in the genome of drosophila hydei. i. preferential localization in the x chromosomal heterochromatin. 19724635991
developmental variations of a deoxyribonuclease in the salivary glands of drosophila hydei and d. melanogaster. 19724670877
metabolic changes during spermatogenesis and thoracic tissue maturation in drosophila hydei. 19724402328
induced accumulation of non-histone proteins in polytene nuclei of drosophila hydei. ii. accumulation of proteins in polytene nuclei and chromatin of different larval tissues. 19724670873
induction of chromosome puffs in drosophila hydei salivary glands after inhibition of rna synthesis by -amanitin. 19725053806
the control of puffing in drosophila hydei. 19724579364
production and release of a locus-specific ribonucleoprotein product in polytene nuclei of drosophila hydei.a specific, 0.1-0.3-microm large ribonucleoprotein complex consisting of a central core with stalklike extensions on top of which 280-320-a ribonucleoprotein particles are situated is found in an experimentally activated chromosome region, 2-48c, of the polytene chromosomes of drosophila hydei. alkaline hydrolysis, rnase digestion, and uranyl-edta-lead staining indicated the ribonucleoprotein character of the 280-320-a particles, whereas the central core seems to be devoid of rna. the characteri ...19734128322
rna metabolism during metamorphosis of drosophila hydei. 19734752422
cell clustering and pleiotropy in white-variegated eyes and malphighian tubes of drosophila hydei.the type of variegation of eyes of white-mottled mutants of d. hydei, either small-spotted or large-spotted, depends on the specific chromosome rearrangement involved. this distinction between mutants, though handsome, is not absolute because very seldomly small-spotted types do show a larger pigment aggregate and some "large-spotted" flies have no large spots at all, but only minor spots. because of a pleiotropic action of the white gene, we could study the variegation of malpighian tubules. th ...19734769300
deoxyribonucleic acid synthesis in isolated polytene nuclei of drosophila hydei. 19734747550
rna synthesis in polytene salivary glands of drosophila hydei maintained under in vitro conditions. 19734792129
in vitro cell differentiation in the testes of drosophila hydei. 19734777721
fibril rings in alkali-urea treated polytene chromosomes of drosophila hydei. 19734713286
ecdysone-binding proteins in haemolymph and tissues of drosophila hydei larvae. 19744424235
the influence of ouabain on the elimination of injected and orally applied dyes in drosophila hydei. 19744421313
modification of the nuclear envelope in polytene cells of drosophila hydei under the influence of vitamin b6. 19744547255
radiation-induced dominant lethality in oocytes of drosophila hydei, with emphasis on the differential sensitivity of the immature stages in class b. 19744854002
influence of ouabain on na+ and k+ concentration in haemolymph of drosophila hydei and appearance of malpighian tubules. 19744852442
the nucleolus in primary spermatocytes of drosophila hydei. 19744854976
a comparative study of in situ hybridization procedures using crna applied to drosophila hydei salivary gland chromosomes. 19744827875
genes controlling chromosome activity. an x-linked mutation affecting y-lampbrush loop activity in drosophila hydei. 19744609704
structure and function of the y chromosome of drosophila hydei. 19744524781
local structural variations of the y chromosome of drosophila hydei and their correlation to genetic activity. 19744524780
structure and function in the genome of drosophila hydei. 19744524779
model approaches for the evaluation of electrical cell coupling in the salivary gland of the larva of drosophila hydei. the influence of lysolecithin on the electrical coupling. 19744444018
intragenic recombination at the white locus of drosophila hydei.a fine-structure analysis of the white locus in drosophila hydei was carried out by means of allele recombination. four mutants, derived from wild type, mapped at three subloci. these are possibly homologous to the main subloci 2, 3, and 4 of d. melanogaster. three secondary mutants, derived from the primary wiv allele, were located in the proximal part of the gene. one of them appeared as a homoallele of the original wiv, whereas the remaining two are better explained either as double mutants o ...19751214776
visualization of gene transcription in spermatocytes of drosophila hydei.x chromosomal and/or autosomal transcriptional activity has been visualized by electron microscopy in primary spermatocyte nuclei of drosophila hydei lacking a y chromosome. the spreading technique applied uses a mixture of a hypotonic medium plus a detergent to disperse single germ cells. no effect of the detergent on the quality of the spread was detected using spread rrna cistrons as a reference. the intervals between the transcripts are highly variable ranging from 0.1 mum to more than 3 mun ...19751212903
new compound (1) chromosomes and the production of large quantities of x/o males in drosophila hydei. 19751225764
induced transcription-dependent synthesis of mitochondrial reduced nicotinamide-adenine dinucleotide dehydrogenase in drosophila.salivary glands of drosophila hydei recovering from an anaerobic treatment show a significant increase in apparent vmax of mitochondrial nadh dehydrogenase. this increase in vmax is based on an increase in enzyme molecules resulting from synthesis de novo in the cytoplasm, as indicated by the inhibition by cycloheximide of both the increase in apparent vmax and the increase in amino acid incorporation into enzyme fractions. the increase in enzyme activity is also inhibited by actinomycin d, whic ...19751212223
the location of 5s (ribosomal) rna genes in drosophila hydei.the location of the 5s ribosomal rna cistrons in band 2-23b1,2 of the polytene (salivary gland) chromosomes of drosophila hydei was indicated by in situ hybridization of tritiated low molecular weight rna fractionated from total in vivo synthesized larval rna or from in vitro synthesized salivary gland rna and competition of the hybridization of this rna by 5s rna obtained from calf lens ribosomes. -- at the submicroscopic level, band 2-23b1,2 in salivary gland chromosomes shows a compact organi ...19751175453
absence of cell communication for fluorescein and dansylated amino acids in an electrotonic coupled cell system.quantitative evaluation of the diffusion process of sodium fluorescein and dansylated amino acids in the salivary gland of the larvae of drosophila hydei reveals that the differences in specific permeability between the junctional and nonjunctional membranes, as found for small ions, do not apply to the fluorescent probes. there are no significant differences between the permeability properties for the different dansylated amino acids tested, and the same properties are found for sodium fluoresc ...19751148233
induced rnp production in different cell types of drosophila.the typical rnp complexes produced in puff 2-48bc in the salivary gland chromosomes as a consequence of treatments interfering with the cellular respiratory metabolism have been found in various other cell types after treatment with 5-10- minus 2 m vitamin b6 for 4 hr. in drosophila hydei the typical rnp complexes were present in puff 2-48bc in the nuclei of gastric caeca cells, in nuclei of cells of the imaginal (wing) discs and embryonic cells in primary culture. similar rnp complexes were obs ...1975806351
minute-type mutants in drosophila hydei. 19751235049
two separated nucleolus organizers on the drosophila hydei y chromosome.by genetical, cytological, and filter saturation hybridization methods it is shown that the y chromosome of drosophila hydei contains two separate nucleolus organizers, one on the short arm, the second near the tip of the long arm.19751186660
the submicroscopic structure of synthetically active units in a puff of drosophila hydei giant chromosomes.thin sections of nuclei of salivary glands of drosophila hydei, treated in vitro with vitamin b-6 in the presence of either actinomycin d or 3'deoxyadenosine revealed the morphology of transcription units observed display a definite polarity with respect to the size of the rnp-particles attached to the deoxynucleoprotein matrix. the length of the longest unit observed was approximately 1.5 micronm, which corresponds well with the size of the rna extracted from isolated puffs and with preliminary ...19751132284
the proteins of polytene chromosomes of drosophila hydei.it is reported that chromatin can be prepared from highly purified polytene nuclei from the salivary glands of third instar larvae of drosophila hydei; such chromatin differs from that of diploid nuclei mainly by deficiencies in certain nonhistone chromosomal proteins. it is suggested that these proteins are important components of constitutive heterochromatin, which is severely underrepresented in polytene chromosomes. chromosome morphology, including the pattern of induced puffs, is maintained ...19751095320
the location of the nucleolus organizer regions in drosophila hydei.the positions of the nucleolus organizer regions in metaphase chromosomes of drosophila hydei were detected by in situ hybridization experiments. in agreement with earlier conclusions the nucleolus of the x chromosome was found to originate in a terminal region of the heterochromatic arm. the y chromosome contains two nucleolus organizers, one in a terminal postion of the long arm, and the other in the short arm. the implications with respect to the evolution of the y chromosome are discussed.1975806438
independent replication of the ribosomal rna genes in the polytrophic-meroistic ovaries of calliphora erythrocephala, drosophila hydei, and sarcophaga barbata.by filter saturation hybridizations the ribosomal (r)dna contents of the ovaries calliphora erythrocephala, drosophila hydei, and sarcophaga barbata have been measured in comparison to the rdna percentages of their diploid brains. the measurements of the ovarian rdna have been carried out on ovaries where the nurse cells in the distal egg chamber of the ovarioles had reached their highest ploidy level. the diploid rdna content of each of the respective species was chosen as a 100% standard and t ...19751201686
variations in the number of the y chromosomal rrna genes in drosophila hydei.the number of rrna cistrons is measured by filter saturation hybridization in different stocks of d. hydei, where the wild-type x chromosome has one nucleolus organizer (no) and wild-type y has two separated no's. xx/y females having no x chromosomal no show an rdna content exceeding that of a y chromosome. an even greater increase in the rrna cistron number is measured in two translocation stocks where the xx is combined with one half of a y and, therefore, each stock contains only one of the t ...1976814041
ribosomal dna content and bobbed phenotype in drosophila hydei.the number of ribosomal rna genes in different drosophila hydei stocks has been determined by filter saturation hybridisation experiments. it has been shown that there is no marked correlation between the average rrna gene number per cell in the whole animal and the bobbed phenotype when y chromosomal nucleolar organisers are present.19761070484
a differential effect of the incubation temperature on the inhibition of rna synthesis by drb in cells of drosophila hydei. 1976992058
rna synthesis with giant chromosomes of isolated drosophila hydei nuclei as a correlate to the experimentally altered chromosome morphology. 1976991944
ribonuclear protein formation at locus 2-48 bc in drosophila hydei. 1976972687
protein synthesis in salivary glands of drosophila hydei after experimental gene induction.several treatments, namely incubation at 37 degrees c, in the presence of arsenite, 2,4-dinitrophenol or vitamin b-6, or release from anaerobiosis induce the same set of puffs in the polythene chromosomes of salivary glands of drosophila hydei. analysis of changes in protein-synthetic patterns (as determined by radioautography of sodium dodecyl sulphate-gel electrophoretograms of extracts from [35s]methionine-labelled salivary glands) showed that concomitant with puff induction by these various ...1976985453
rna synthesis in puff 2-48bc after experimental induction in drosophila hydei.puffs induced by treatment with vitamin b6 at locus 2-48bc in salivary gland cells of drosophila hydei were isolated by micromanipulation, and the puff rna was analyzed electrophoretically. the main rna species migrated with a mobility of 40s. a similar rna species was found in this puff after its induction by temperature treatment, except that in this case material with a higher mobility was also found, presumably due to the presence of growing chains. no evidence was found for polyadenylation ...1976971486
cytochemical studies on rnp complexes produced by puff 2-48bc in drosophila hydei: uranyl acetate and phosphotungstic acid staining.differential staining of the core and rnp particles of rnp complexes in puff 2--48 bc in salivary gland chromosomes of drosophila hydei was achieved with aqueous uranyl acetate (ua) at low ph, with ua in acetone, with phosphotungstic acid (pta) in organic solvents, and with aqueous pta at ph 5 and 6. a comparison of the results of ua and pta staining under various conditions indicate that the proteins in the core region and in the rnp particles connected to it differ with respect to their amino- ...197656256
size and distribution of polyadenylic acid sequences in drosophila polytene dna and rna.[3h]poly(u) hybridizes very rapidly to polytene dna from drosophila hydei. when hybridization is performed at 30 degrees c in 2 x ssc to a large excess of dna, 95% of the poly(u) becomes ribonuclease resistant. also, complementary rna transcribed in vitro from polytene dna hybridizes to poly(u). 023--0.25% of the dna is composed of (da)-rich sequences and 0.23--0.31% of crna hybridizes to [3h]poly(u). the length of the (da)-rich sequences on the dna and crna is 40 nucleotides. the tm values of t ...1977921997
chromosomal puff induction in salivary glands from drosophila hydei by arsenite. 1977913493
dna distribution and intrachromosomal organization of moderately repetitive sequences.the dna content of individual subregions along the 4th chromosome of drosophila hydei has been measured. 51% of the subregions have a dna content averaging 0.7-0.8 pg; 31% a mean dna content of 0.25-0.35 pg and 18% a mean dna content of 1.7 pg. moreover the structural chromosomal distribution of moderately repetitive dna is not random since the specific activity of the chromosomal segments in terms of those sequences is not the same. 9% of the subregions are very poor in repetitive sequences and ...1977610873
abnormal microtubules in testes of the mutant l(3)pl (lethal-polyploid) of drosophila hydei, cultured in vivo. 1977559579
morphogenetic deficiencies in transplanted gonadal anlagen of the mutant l(3)pl (lethal-polyploid) in drosophila hydei. 1977559578
selective staining of y chromosomal loops in drosophila hydei, d. neohydei, and d. eohydei.modified giemsa procedures have been developed which elicit differential and highly selective staining of individual y chromosomal lampbruch loops in spermatocyte nuclei of drosophila hydei, d. neohydei, and d. eohydei. in all three species the y loop pair known as the "clubs" stains a brilliant dark red with giemsa at ph 10. with the same treatment other loop pairs either remain unstained, e.g. the "threads", or show a differentiation between light blue and pink staining material, e.g. "pseudon ...197767013
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