Publications

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amino acid content of dehydrated giant african snails (achatina fulica bowdich). 195313038463
disease in the giant african snail achatina fulica bowdich. 195617793431
a comparison of hydrolase and lytic activities of the digestive juices of the giant african snail, achatina fulica, and helix pomatia. 196313981006
urine formation in a pulmonate land snail, achatina fulica. 196514294948
the presence of angiostrongylus cantonensis in islands of the indian ocean and probable role of the giant african snail, achatina fulica, in dispersal of the parasite to the pacific islands. 19665981486
orthomorpha sp.--a new predatory millipede on achatina fulica in andamans. 19676062908
application of calcium arsenate: histopathological changes & glycogen mobilization in achatina fulica bowdich. 19705502342
the giant african snail, achatina fulica. a new threat to public health. 19715104773
the prevalence of angiostrongylus cantonensis larvae collected from the giant african snail, achatina fulica in west malaysia and singapore. 19715144153
the infectivity of third stage angiostrongylus cantonensis larvae shed from drowned achatina fulica snails and the effect of chemical agents on infectivity. 19715168426
purification of -mannosidase from a snail, achatina fulica, and its action on glycopeptides. 19725026310
a neoplasm in the giant african snail achatina fulica. 19724655537
histopathological changes in the gut of achatina fulica bowdich caused by endrin--a molluscicide. 19724665445
trypsin inhibitory activity associated with the subunit of the haemocyanin of achatina fulica. 19734714908
[concentration of inorganic ions in the hemolymph of the giant african snail (achatina fulica ferussac) as a function of its nutritional state]. 19734785100
[free amino acid levels in the hemolymph and neural ganglia of the giant african snail(achatina fulica ferussac) while starved and fed]. 19734793572
proceedings: 48. on the identified molluscan giant neurone sensitive to serotonin and dopamine (achatina fulica ferussac). 19734799250
ecological studies on the breeding of aedes aegypti and other mosquitos in shells of the giant african snail achatina fulica.the breeding of larvae of aedes aegypti, aedes simpsoni, and eretmapodites quinquevittatus in empty shells of achatina fulica was studied in the coastal zone of dar es salaam, tanzania. the average density of shells was estimated to be 228 per ha. from 11 to 35% were positive for mosquito larvae. a. aegypti were found in 82-84% of positive shells; a. simpsoni in 8-13%. on msasani peninsula, during the 3-month rainy season april-june 1970, the larval density of a. aegypti in shells was estimated ...19734148745
amounts of inorganic ions and free amino acids in hemolymph and ganglion of the african giant snail, achatina fulica ferussac. 19744151962
[effect of catecholamines and their analogs on the electric activity of a giant neuron identified in the subesophageal ganglia of the giant african snail (achatina fulica ferussac)]. 19744281710
[effect of indolamines and their analogs on the electric activity of on identified giant neuron of achatina fulica ferussac]. 19744281711
effects of sulfur-containing amino acids on the electrical activity of an identified giant neuron in subesophageal ganglia of the african giant snail, achatina fulica ferussac. 19744470428
angiostrongylus cantonensis infection in achatina fulica from taiwan. 19744479559
[the african giant snail (achatina fulica) as experimental intermediate host of angiostrongylus vasorum (nematoda) (author's transl)]. 19744849972
the effect of amino acids on the excitability of identified autoactive giant neurons of achatina fulica férussac.effects of the following amino acids were examined on the electrical activity of the two giant neurones (pon and tan) identified in the subesophageal ganglia of achatina fulica férussac : l-asp, l-thr, l-ser, l-glu, l-pro, gly, l-alpha-ala, beta-ala, l-cysteine, l-cystine, l-val, l-met, l-ileu, l-leu, l-tyr, l-phe, l-lys, l-his, l-arg, l-cit, l-try, gaba and gabob. among these substances, we observed an inhibitory effect of gaba and gabob on the tan excitability. gaba showed stronger effect on t ...19752374
[catecholamines in the sub-esophageal ganglia and the hemolymph of the giant african snail (achatina fulica férussac) determined by gas chromatography].the content of three catecholamines (dopamine, l-norepinephrine and l-epinephrine) in the subesophageal ganglia and the hemolymph of achatina fulica férussac was measured by a gas chromatograph with electron capture detector. the dopamine content of the ganglia was 4.3 +/- 0.9 mug/g. l-norepinephrine and l-epinephrine in the ganglia were not detected. the three catecholamines in the hemolymph were also not detected.1975129245
[relationship between current and voltage in neuromembranes measured by a generator of long-term triangular current].a generator of triangular current of long duration was constructed to measure the current-voltage relationship (i-v curve) of neuromembranes. using this instrument, we observed the effect of 5-hydroxytryptamine (5-ht) on the i-v curve of an identified giant neurone (pon) of achatina fulica férussac. when two i-v curves (measured in the physiological state and under the 5-ht application) were superimposed by using the firing level as the common standard point, a concordance of two i-v curves in w ...1975129248
epidemiologic studies of eosinophilic meningitis in southern taiwan.a study of the epidemiologic characteristics of 125 cases of eosinophilic meningitis or meningoencephalitis, probably caused by angiostrongylus cantonensis, which occurred in southern taiwan in 1968 and 1969 revealed a close association of the disease with the rainy season. in contrast to findings in other geographic areas, most such cases in this study occurred among children. a higher attack rate was observed among aborigines than among descendants of mainland chinese. most patients had eaten ...19751155688
inhibitory effect of beta-hydroxyglutamic acid on a molluscan giant neurone.we found a spontaneously firing neurone, inhibited by beta-hydroxy(erythro)-l-glutamic acid, identified in the subesophageal ganglia of an african giant snail (achatina fulica férussac), although this neurone is not sensitive to l-glutamic acid. we suggest that beta-hydroxy(erythro)-l-glutamic acid may be a putative inhibitory synaptic transmitter of the identified molluscan neurone.19751213058
effects of glutamic acid relatives on the electrical activity of an identified molluscan giant neurone (achatina fulica férussac).effects of glutamic acid and its relatives were examined on the electrical activity of two kinds of neurones (the pon, periodically oscillating neurone, and the tan, tonically autoactive neurone) identified in the suboesophageal ganglia of an african giant snail, achatina fulica férussac. l- and d-glu, l-asp, gly and beta-ala did not show any effect on the two neurones. however, beta-hydroxyglutamic acid (bhga) showed a remarkable inhibitory effect on the pon. erythro-l-bhga had the strongest ef ...19761252919
[effects of histamine and its derivatives on the excitability of a giant identifiable neuron of achatina fulica férussac. a histaminergic receptor different from h1 and h2].a giant neurone of achatina fulica férussac (the tan, tonically autoactive neurone) is excited by histamine. pharmacological characteristics of its histaminergic reception are quite different from those of h1 and h2 receptors. the effect of histamine on the tan is antagonized by neither mepyramine nor burimamide.1976139986
effects of physalaemin, a vaso-active peptide from amphibian skin, on the excitability of an identifiable molluscan giant neurone of achatina fulica férussac.we examined effects of several vasoactive peptides (substance p, physalaemin, neurotensin, bradykinin, angiotensin etc.) on the excitability of molluscan giant neurones identified in the subesophageal ganglia of achatina fulica férussac. of these peptides, only physalaemin showed a remarkable excitatory effect on a giant tonically autoactive neurone.19766298
effects of guanidino compounds on the electrical activity of giant neurons identified in subesophageal ganglia of the african giant snail, achatina fulica ferussac. 19768256
[histological studies of the african giant snail (achatina fulica) experimentally infected with angiostrongylus vasorum or angiostrongylus cantonensis (author's transl)].african giant snails (achatina fulica) about 6 weeks old were experimentally infected with each 5,000 to 20,000 first stage larvae of angiostrongylus vasorum or a. cantonensis by exposure to a larval suspension. the snails were histologically examined after various intervals after infection: 1 hour post infectionem (p.i.) larvae were present in the foot and 2 hours p.i. in addition in the gastrointestinal tract. 12 hours p.i. larvae were seen for the first time in the lung which reached nearly h ...1976790803
comparative studies on different small intestinal oligosaccharidase activities in some vertebrates and invertebrates like molluscs.oligosaccharidase activities of the small intestinal mucosal homogenates were measured in vertebrates viz fish, toad, garden-lizard (calotes), pigeon, rat and some invertebrates viz, molluscsa. maximum activities of the enzymes lactase, sucrase and maltase were found in the mammalian species rat, whereas much less activities were found in the non-mammalian vertebrates among which toad shows the highest values and garden lizard the lowest. among the invertebrates pila globosa shows higher values ...1976977083
effects of three synthetic peptides analogous to neurophypophyseal hormones on the excitability of giant neurones of achatina fulica férussac.deamino-dicarba-(d-d)oxytocin and d-d-arg-vasotocin at 10(-4)kg/l showed an excitatory effect on the periodically oxcillating neurone (pon) of achatina fulica férussac. d-d-arg-vasopressin had no effect.19761021447
growth and localization of angiostrongylus cantonensis in the molluscan host, achatina fulica.the development of the rat lung worm angiostrongylus cantonensis within the giant african snail achatina fulica is reported. in this host, ingested first stage larvae penetrate the intestinal wall into the hemocoel and migrate to the mantle where they undergo two molts and become third stage larvae within 24 days. the mantle, harboring 85% of the total number recovered is the major location of infective larvae. the kidney contains about 11% but few larvae are found in the remaining visceral org ...19761027104
the bandicoot rat, a new host record for angiostrongylus cantonensis in indonesia.a survey for angiostrongylus cantonensis in possible definitive and intermediate hosts was conducted in ancol, jakarta. adult worms were found in 43% of bandicoot rats, bandicota indica setifera, in 14% of rattus rattus diardii and 36% of the achatina fulica were infected with larval forms of the parasite. the finding of the parasite in the bandicoot rat constitutes a new host record for indonesia.19761027106
angiostrongylus malaysiensis from tuaran, sabah, with reference to the distribution of the parasite in malaysia.a survey of angiostrongylus malaysiensis among wild rodent and molluscan hosts was made in the tuaran central agricultural research station and within the vicinity of tuaran, sabah. three of 19 rattus rattus diardii, one of 2 r. exulans and one r. argentiventer were found naturally infected with the parasite. in this survey 56 of 382 molluscs comprising of pila scutata, achatina fulica and two species of land slugs, laevicaulis alte and microparmarion malayanus, were found naturally infected wit ...19761030843
different glycosubstances and galactans in the albumin gland and eggs of achatina fulica.in saline extracts from the eggs and the albumin gland of the snail achatina fulica 3 different forms of glycosubstances have been found by using heterophile precipitins from different sources: 1. an alkali-stable galactan reacting with the anti-galactans from axinella polypoides sponge and from the clam tridacna maxima (tridacnin) and with concanavalin a. 2. another glycosubstance giving cross-reactions with a second precipitin from axinella polypoides, with the lectin from ricinus communis, wi ...19761034378
[presence of angiostrongylus cantonensis in the réunion island. isolation of the strain].the detection of some cases of eosinophilic meningitis suggest that angiostrongylus cantonensis is present in reunion island. larvae of this nematode have been isolated after dissection of achatina fulica and have been used to infest laboratory rats. 30 days later, the dissection of these animals shows the presence of young worms in the brain and in the pulmonary arteries. 45 days later, first-stage larvae are recovered from the feces of animals. now, the strain is maintained in biomphalaria gla ...19761037434
degradation of poly da by a deoxyribonuclease preparation from a land snail, achatina fulica. 19761087153
homologous neurosecretory cell groups in the land snail achatina fulica and the sea slug aplysia californica.the right parietal ganglion of the african snail achatina fulica contains an identifiable cluster of 20-40 white cells with somatic diameters of 80-110 mu. cobalt chloride injection into these cells revealed an axon projection in the right parietal nerve as well as apparent terminations in the capsule. the cells contain an abundance of electron dense granules 1000-2000 a in diameter which are formed in the golgi apparatus. the granules stain with gomori's chrome hematoxylin and paraldehyde fuchs ...1977837391
modification of effects of biologically active peptides, caused by enzyme treatment, on the excitability of identifiable giant neurones of an african giant snail (achatina fulica férussac).physalaemin, which excites an identifiable mooluscan giant neurone (the tan, tonically autoactive neurone), lost the effect after the trypsin treatment. unexpectedly, this peptide shows an inhibitory effect on the same neurone after chymotrypsin treatment. deamino-dicarba-(d-d-)oxytocin and d-d-arg-vasotocin, which excite another identifiable neurone (the pon, periodically oscillating neurone) continue to show the effect after chymotrypsin treatment (6 h). but d-d-arg-vasotocin losts the effect ...1977844577
a long-term memory for food odors in the land snail, achatina fulica. 1977849227
effects of ibotenic acid, quisqualic acid and their relatives on the excitability of an identifiable giant neurone of an african giant snail (achatina fulica férussac).an identifiable giant neurone, pon (periodically oscillating neurone), of achatina fulica ferussac, inhibited by erythro-beta-hydroxy-l-glutamic acid, was also inhibited by 2 relatives of beta-hydroxy glutamic acid, ibotenic acid and quisqualic acid. these substances similarly showed the effect on the neurone even in the chloride-free medium.1977858370
effects of some oligopeptides, consisting of aromatic amino acids, on the excitability of an identifiable giant neurone of an african giant snail (achatina fulica férussac).l-phe-l-tyr and l-lys-l-phe-l-tyr showed a marked inhibitory effect (not chloride-dependent) on the excitability of an identifiable giant neurone (the tan) of achatina fulica férussac, while l-tyr-l-phe, l-tyr-l-tyr, l-phe-l-phe, l-lys-l-phe and z-l-phe-l-tyr (z-: carbobenzoxy) had no effect.1977908410
effects of biologically active peptides on the excitability of identifiable giant neurones of an african giant snail (achatina fulica férussac). 1977917265
[development of angiostrongylus cantonensis in the lung of achatina fulica (author's transl)].twenty-four achatina fulica from pai-sha of the pescardores islands, where no angiostrogylus cantonensis has been found in a. fulica(4), were inoculated with the first stage larvae of a cantonensis. one snail was killed every day after 24 days following inoculation. the lung of each snail was separated and examined for larvae under microscope. the same lung was then digested with pepsin. the larvae recovered after pepsin digestion were examined for more detailed morphology. this study confirmed ...1977580235
structure-activity relationships of gaba and its relatives on the excitability of an identified molluscan giant neurone (achatina fulica férussac). 197711957
structure-activity relationships of l-homocysteic acid and its relatives of the electrical activity of an identifiable molluscan giant neurone (achatina fulica férussac). 197715780
deoxyribonuclease a, a novel deoxyribonuclease highly active toward polydeoxyadenylic acid and polythymidylic acid from achatina fulica.two novel deoxyribonucleases, termed dnases a and a', have been purified from the hepatopancreas of achatina fulica (agate snail). dnases a and a' were obtained in 3.6 % and 7.7% yields by acetate buffer extraction and successive chromatography on hydroxyapatite, phosphocellulose and poly(a)-sepharose. the two dnases are highly active toward poly(da) and at a salt concentration of 0.15 m and ph 5.0 exhibit 10-fold higher hydrolyzing activities toward poly(da) than toward calf thymus denature dna ...197721173
[classification of the responses of a giant neuron from the snail acatina fulica férussac, caused by inhibitory sugstances depending on chlorine ions].gaba, three of its derivatives (l-gabob, d-gabob and delta-amino valeric acid), acetycholine (ach), dopamine (da) and l-phe-tyr all inhibit an identifiable giant neurone (the tan, tonically autoactive neurone) of achatina fulica. these effects were examined by microdrop application in two different conditions: in physiological solution and in the absence of chloride ions. the results show that the relatively transient (rapid) inhibitions caused by gaba, by its derivatives and by ach are dependen ...1977144014
immunogenicities of haemocyanins from the giant african snail (achatina fulica) and the keyhole limpet (megathura crenulata).1. the immunogenicities of the giant african snail (achatina fulica) haemocyanin (afh) and the keyhole limpet (megathura crenulata) haemocyanin (klh) were compared by determining their capacities to induce humoral and cell-mediated immune response in rats. 2. klh was found to be more immunogenic than afh, and this was attributed to the fact that klh contains more moieties, and probably more antigenic determinants than afh. 3. since afh was found capable of stimulating both humoral and cell-media ...1977318245
[inhibitory effects of dipeptides containing tryptophan on the excitability on the giant neuron of the giant african snail (achatina fulica, ferussac)].besides an inhibitory effect of l-lys-l-phe-l-tyr and l-phe-l-tyr, l-phe-l-trp showed the same effect on the excitability of a giant neurone (the tan, tonically autoactive neurone) identified in suboesophageal ganglia of achatina futica férussac. the critical concentration of l-phe-l-trp to produce the effect was 10(-5)--3 x 10(-5) kg/1. the inhibitory effect of this substance was relatively slow and independent no chloride ions, as well as in the case of l-phe-l-tyr. l-trp-l-phe, gly-l-trp and ...1978153196
grouped spike discharges of an identifiable neurone of a snail (achatina fulica férussac) produced in isotonic foreign anion solutions. 197826499
isolation and some properties of two deoxyribonucleases from a snail, achatina fulica.1. two main dnases were found in the dried liver extract of a snail, achatina fulica. they were purified by the phosphocellulose batch method and by phosphocellulose column chromatography. the enzyme eluted earlier from the phosphocellulose column was designated as achatina dnase-1 and the other as achatina dnase-2. dnase-1 was purified further by qae-sephadex a-25 column chromatography (twice) just before use because of the instability of the purified enzyme. by these procedures, dnase-1 and 2 ...197831355
penetrable and impenetrable anions into the gaba-activated chloride channel on the postsynaptic neuromembrane of an identifiable giant neurone of an african giant snail (achatina fulica férussac). 197832999
responses to conspecific chemical stimuli in the treatment snail achatina fulica (pulmonata: sigmurethra). 1978626626
attraction of the snail achatina fulica to extracts of conspecific pedal glands. 1978678253
current(i)-voltage(v) relationships of the neuromembrane of an identifiable giant neurone of an african giant snail (achatina fulica férussac) in the presence of an inhibitory tripeptide, l-lys-l-phe-l-tyr.an inhibitory tripeptide, l-lys-l-phe-l-tyr, caused membrane hyperpolarization of the tan (tonically autoactive neurone) resulting in an elevated firing level. the tripeptide, however, did not markedly affect either the tan i-v curve or the firing pattern obtained by transmembrane triangular current injection.1978700024
effects of parasitism and stress on hemolymph protein of the african giant snail, achatina fulica.effects of parasitism and stress on the protein concentration of hemolymph have been investigated using the rat lungworm angiostromgylus cantonensis in the snail host achatina fulica. the normal hemolymph protein concentration, averaging 1.77 g/100 ml in noninfected snails, did not show any reduction when the hosts were infected with third stage larvae. when the infected snails were bled repeatedly, protein concentration showed a significant decrease by 0.6 g/100 ml. starved, infected snails wer ...1978735303
angiostrongyliasis in indonesia: additional geographic and host occurrence records.geographical and host occurrence records for angiostrongylus cantonensis throughout the indonesian archipelago a;e reported. a. cantonensis was found in the following provinces: west sumatra, south sumatra, lampung, west java, central java, north sulawesi and east nusa tenggara. infections were diagnosed in the following rodents: rattus rattus diardii, rattus exulans, rattus tiomanicus jaloriensis, rattus lepturus, rattus norvegicus and bandicota indica setifera and in the giant african land sna ...1978751218
responses of the intestine of the giant african snail (achatina fulica) to acetylcholine in meng's solution with low sodium, potassium and calcium ions.decreasing the concentration of sodium in meng's solution produced a non-parallel shift of the dose-response of acetylcholine on the intestine of the giant african snail achatina fulica. this decrease in sodium decreases the sensitivity of the tissue to acetylcholine and sensitivity was not restored with several washings. the response to decrease calcium is very similar to that of sodium. in the case of potassium however 10% k+ produced less depression in sensitivity than 25% which even caused l ...1978751678
acetylcholinesterase in the central nervous system and digestive gland of achatina fulica bowdich.cholinesterase (che) activity was measured in the central nervous system (cns) and in the digestive gland of the pestiferous land snail achatinafulica bowdich, by the method of huegra et al. (1952). acetylcholinesterase (ache), and benzoylcholinesterase (beche) activity was higher in the former than in the latter. the complete inhibition of the enzyme activity with 10(-2) m eserine indicates that the che examined is ache. the km values of the ache from the digestive gland and the cns were 3.1 x ...197945327
[effects of 2 water-soluble contrast media, meglumine iothalamate (conray) and meglumine iocarmate (dimer-x), on the electric activity of identifiable giant neurons of the african giant snail (achatina fulica ferussac)].the influences of two water soluble contrast media, meglumine iothalamate and meglumine iocarmate, on the neuronal excitability and on the neuronal sensitivity to putative transmitters were examined in comparison with those of sucrose using two identifiable giant neurones of achatina fulica férussac (the tan and the pon). a relatively low increase of osmotic pressure of the extracellular fluid, produced by the application of contrast media, reversed the cl- dependent inhibition caused by a putat ...1979161197
[effect of oligopeptides containing l-phe, l-tyr, l-trp, l-his or l-met on the excitability of the 2 giant neurons of the african giant snail (achatina fulica ferussac)].effects of about ninety oligopeptides, containing l-phe, l-tyr, l-trp, l-his and l-met, on the excitability of two identifiable giant neurones (the pon, periodically oscillating neurone ; and the tan, tonically autoactive neurone) of achatine fulica férussac were examined. three oligopeptides, l-lys-l-phe-l-tyr, l-phe-l-tyr and l-phe-l-trp, showed an inhibitory effect on the pon. however, this effect on the pon was weaker than that of the same three peptides on the tan. [the latter has been repo ...1979161198
quantitative determinations of some pharmacological effects from the edible giant african snail (achatina fulica). 1979463339
achatina fulica hemocyanin and its interactions with imidazole, potassium cyanide, and fluoride as studied by spectrophotometry and nuclear magnetic resonance and resonance raman spectrometry. 1979465458
inhibitory effects of aromatic oligopeptides on the excitability of identifiable giant neurones of an african giant snail (achatina fulica férussac).effects of an aromatic tripeptide, l-lys-l-phe-l-tyr and its related dipeptides on the excitability of two identifiable giant neurones (the tan, tonically autoactive neurone and the pon, periodically oscillating neurone) in the suboesophageal ganglia of the african giant snail, achatina fulica férussac, were examined. of 33 substances examined, three aromatic oligopeptides showed a marked inhibitory effect on the tan excitability. the critical concentrations of these substances in bath applicati ...1979485679
pharmacological effects of the giant african snail achatina fulica.the body fluid and tissue extract of the foot of achatina fulica, the edible giant african snail, were investigated and quantified for pharmacological effects. both reduced spontaneous locomotor activity in mice, protected them from death from amphetamine induced toxicity, prolonged hexobarbitone sleeping time and caused a depletion of catecholamines from various organs of the rat. from this a central depressant action combined with an antihypertensive effect is inferred. this is in keeping with ...1979524451
excitatory effects of ergot alkaloids and their derivatives on the excitability of an identifiable giant neuron of the african giant snail (achatina fulica férussac).the effects of various ergot alkalids and related substances on the neuronal excitability were examined using a spontaneously firing neuron (pon, periodically oscillating neuron) identified in the suboesophageal ganglia of the african giant snail (achatina fulica férussac). of the substances examined, ergometrine and methylergometrine had a marked excitatory effect on the neuron (their critical concentration by bath application: 5 x 10(-6) kg/l). d-lysergic acid (the critical concentration: 3 x ...1979526072
[different effects of the replacement of extracellular sodium with lithium on the abnormal spike discharges caused by 2 convulsants, metrazol and strychnine, on an identifiable giant neuron of the mollusc achatina fulica ferussac].the influences of the replacement of sodium with lithium in the extracellular medium on the abnormal spike discharges, caused by two convulsants, metrazol and strychnine, of a giant neurone (tan, tonically autoactive neurone) identified in the suboesophageal ganglia of the african giant snail (achatina fulica férussac) were examined. the slow oscillations of potential caused by metrazol disappeared after this replacement. on the other hand, the abnormal action potentials caused by strychnine, as ...19806448671
[effects of clavines, ergot alkaloids, on the membrane potential of an identifiable giant neuron of the african giant snail achatina fulica ferussac].the effects of seven clavines, alkaloids of ergot, on the electrical activity of an identifiable giant neurone (tan, tonically autoactive neurone) of the african giant snail were examined. all the substances examined, lysergine, agroclavine, elymoclavine, festuclavine, chanoclavine, rugulovasine a and rugulovasine b, at 2 x 10(-4) kg/l have no constant effect on tan, indicating that they have no direct effect on this neurone. however, the substances examined, except for chanoclavine, in the same ...19806448672
the effects of aromatic amino acid derivatives on the excitability of an identifiable giant neurone of the african giant snail (achatina fulica férussac).1 the effects of derivatives of aromatic amino acids on the excitability of an identifiable giant neurone (tan, tonically autoactive neurone) of the african giant snail (achatina fulica férussac) were examined. 2 the following substances had marked inhibitory effects on tan using bath application: n-beta-phenylpropionyl-l-tyr and n-beta-phenylpropionyl-l-trp (critical concentration, 3 x 10(-7) m), n-beta-phenylpropionyl-l-phe, n-cinnamoyl-dl-trp and n-phenoxyacetyl-l-trp (critical concentration, ...19807378654
inhibitory effects of ergot alkaloids and their derivatives on the excitability of an identifiable giant neurone of the african giant snail (achatina fulica férussac).the effects of ergot alkaloids and their derivatives on the excitability of an identifiable giant neurone, tan (tonically autoactive neurone), found in the suboesophageal ganglia of the african giant snail (achatina fulica férussac) were examined. ergometrine and methylergometrine had the strongest inhibitory effects. the critical concentrations were 3 x 10(-5) approximately 10(-4) kg/l. the three hydrogenated ergot derivatives, 9, 10-dihydroergocristine, 9, 10-dihydroergocryptine and 9, 10-dihy ...19807406602
carbohydrate reserves and hemolymph sugars of the african giant snail, achatina fulica in relation to parasitic infection and starvation.in the snail, achatina fulica, parasitized by the rat lungworm angiostrongylus cantonensis, levels of carbohydrate in hemolymph and digestive glands were determined. the normal level of hemolymph glucose of 11.7 mg% dropped to 4.25 mg% in the infected snails, a significant difference after only one week of infection. the level of total reducing sugar in the hemolymph also decreased significantly (12.3 mg% to 3.6 mg%) in this period. later on, the snails were capable of adapting themselves to the ...19807415419
aggregation in snails, achatina fulica. 19807447872
dnase a, a poly(da) and poly(dt)-specific deoxyribonuclease from achatina fulica. purification and characterization.dnases a1 and a2 have been purified to homogeneity from the hepatopancreas of achatina fulica by a series of steps: acetate buffer extraction, ammonium sulfate precipitation and column chromatography on hydroxylapatite, phosphocellulose, blue-sepharose, and poly(a)-sepharose. the purified enzymes are free of acidic phosphomonoesterase, phosphodiesterase, and rnase activities. they are slightly acidic glycoproteins with identical isoelectric point (6.90). on 0.1% sds gel electrophoresis, dnase a2 ...19817338515
dnase a, a poly(da) and poly(dt)-specific deoxyribonuclease from achatina fulica. further investigation on the specificity.the degradation of heat-denatured and native calf thymus dnas, poly(da-dt), poly(da-dc) . poly(dg-dt), and poly(dg-dc) by dnase a has been investigated with the main aim of providing background information for studying the specificity of the enzyme. the specificity of the dnase a was studied by determining the base compositions of 5'- and 3'-terminal nucleotides of oligonucleotides released by the enzyme. the 5'- and 3'-terminal nucleotide compositions were found to vary in the average chain len ...19817338516
a circadian locomotor rhythm in the giant land snail, achatina fulica.a circadian rhythm in the locomotor behavior of the giant land snail, achatina fulica, was studied by a running wheel method in a 24 hr light-dark cycle (ld 12:12) and also in constant dim light. the locomotor rhythm could be entrained to the ld cycle, and the entrained rhythm was characterized by the bulk of activity in the dark period, the major activity appeared in the first half of the dark period. in constant dim light the locomotor rhythm free-ran with a period of about 24 hr.19827101281
eosinophilic radiculomyeloencephalitis: an angiostrongyliasis outbreak in american samoa related to ingestion of achatina fulica snails.for the first time in american samoa an outbreak of eosinophilic radiculomyeloencephalitis was related to eating giant african snails (achatina fulica) infected with angiostrongylus cantonensis. among 24 korean fisherman sharing the same infective meal, 16 who ate raw or partially cooked snails became ill; five who ate boiled snails and three who ate none remained well. the ensuing illnesses began within 1-6 days, persisted up to 10 weeks, and were characterized by both peripheral blood and spin ...19827149098
structure-activity relationships of n-beta-phenylpropionyl-l-tyrosine and its derivatives on the inhibition of an identifiable giant neurone of an african giant snail (achatina fulica férussac).1 inhibitory effects of n-beta-phenylpropionyl-l-tyrosine, n-beta-phenylpropionyl-l-tryptophan and their derivatives on an identifiable giant neurone, tan (tonically autoactive neurone) of an african giant snail (achatina fulica férussac) were examined in an attempt to elucidate which structural features are necessary to produce the effect. 2 of the compounds examined, n-beta-cyclohexylpropionyl-l-tyrosine showed the strongest effect. its critical concentration (c.c.) was 3 x 10(-8)-10(-7)m, abo ...19827150871
effects of n-beta-phenylpropionyl-l-tyrosine and its derivatives on the excitability of an identifiable giant neuron of achatina fulica férussac.1. previously the authors demonstrated the inhibitory effects of the two aromatic amino acid derivatives, n-beta-phenylpropionyl-l-tyr (critical concentration (c.c.), 3 x 10(-7) - 10(-6) m) and n-beta-phenylpropionyl-l-trp (c.c., 10(-6) m) on the excitability of an identifiable giant neuron, tan (tonically autoactive neuron), of achatina fulica férussac. the effects of the derivatives of the two inhibitory compounds on the same neuron are examined in the present study. 2. n-beta-cyclohexylpropio ...19826128142
identification of three further giant neurons, r-apn, inn and fan, in the caudal part on the dorsal surface of the suboesophageal ganglia of achatina fulica férussac.in addition to the neurons of achatina fulica férussac examined previously, three more giant neurons, r-apn (right-anterior pallial neurons), inn (intestinal nerve neuron) and fan (frequently autoactive neuron), were identified in the suboesophageal ganglia of the same animal. r-apn (200-250 microns in diameter), the somatic membrane of which was usually silent, was found near the exit of the right anterior pallial nerve in the right parietal ganglion. the most important feature in identifying t ...19836139265
effects of synthetic ergot derivatives on the two identifiable giant neurons, sensitive to dopamine, of achatina fulica ferussac.on the two dopamine (da)-sensitive giant neurones, pon (periodically oscillating neuron, excited by da) and tan (tonically autoactive neuron, inhibited by da), of an african giant snail (achatina fulica férussac), effects of synthetic ergot derivatives, including lisuride and pergolide, which are considered to be dopamine agonists, were examined. of the substances examined, three of the ergot derivatives related to pergolide, d-8,9-didehydro-6-propylergoline-8-methanol (ly149174), d-6-methyl-8 b ...19836140111
neuronal elements in snail tentacles as revealed by horseradish peroxidase backfilling.the snail tentacle ganglion is a prominent structure that innervates an epithelial pad sensitive to wind and odors. its neural composition, and that of the sensory pad, was studied in the terrestrial snail achatina fulica by applying horseradish peroxidase to the distal end of the cut tentactle nerve. five types of neurons were labelled by the procedure: receptors, located in the subepithelial region; three kinds of interneurons, located in the ganglion and its digitlike extensions; and a bipola ...19836827261
morphology and odor sensitivity of regenerated snail tentacles.this study examined certain structural and functional aspects of the olfactory system in regenerated posterior tentacles of the terrestrial snail achatina fulica. regeneration of the epithelial sensory pad occurs with accurate size regulation. all five neuronal cell types which are normally revealed by horseradish peroxidase backfilling are also regenerated. the sensory cells attain normal numbers at about 20 weeks postlesion. the organization of neuronal elements within the tentacle is chaotic, ...19836827262
[ordering of lipids and lipid-protein complexes in molluscan mucus and human bile].optic-morphological characteristics and crystallization of mucus of land snails achatina fulica (bowditch) are compared with cervical secret and also with the human bile. typical defective structures of mesophases: spheroliths, regions of confocal and fan textures containing various classes of line defects are shown. crystallization of protein and lipid fractions is shown to proceed separately, while the dendrite mechanism is typical for the former and for the latter the dislocational growth of ...19836871265
identification and pharmacological characteristics of the two giant neurons, v-rpln and v-vnan, on the ventral surface in the suboesophageal ganglia of the african giant snail (achatina fulica férussac).two giant neurons, v- rpln (ventral-right parietal large neuron) and v- vnan (ventral-visceral noisy autoactive neuron), were identified on the ventral surface in the caudal part of the suboesophageal ganglia of the african giant snail (achatina fulica f erussac ), and their pharmacological features to the common putative neurotransmitters and their related substances were examined. the giant neuron examined, v- rpln , is situated in front of the exit of the right anterior pallial nerve in the r ...19846144435
effects of alpha-kainic acid, domoic acid and their derivatives on a molluscan giant neuron sensitive to beta-hydroxy-l-glutamic acid.no identifiable giant neuron of an african giant snail (achatina fulica férussac) was found to be sensitive to l-glutamic acid (l-glu). however, some of them, including the rapn (right anterior pallial neuron), were sensitive to beta-hydroxy-l-glutamic acid (l-bhga). the effects on rapn of alpha-kainic acid (alpha-ka), domoic acid (dma) and their derivatives, which are structurally related to l-glu and l-bhga, were examined in order to elucidate the chemical structures necessary to produce the e ...19846148251
a new cold agglutinin from achatina fulica snails.an electrophoretically homogeneous agglutinin was purified from the albumin gland of achatina fulica snails using asialofetunin-sepharose 4b as an affinity column. the agglutinin was found to be temperature sensitive; it agglutinated rabbit and human umbilical cord erythrocytes only at low temperature. it was found to be specific for methyl-beta-d-galactoside, and the best inhibitor was n-acetyllactosamine.19846465901
angiostrongylus cantonensis in east new britain, papua new guinea.the first case of angiostrongyliasis (eosinophilic meningitis) to be diagnosed in papua new guinea in 1977, led to a survey of adult melanesian residents of east new britain province where the case occurred, to assess the level of immunological responsiveness to angiostrongylus cantonensis. in 104 subjects tested using an indirect fluorescent antibody test, the serum antibody titres to a. cantonensis equalled or exceeded 1:16 in 50.7% and ranged from 1:32 to 1:64 in 17.3% of subjects. no individ ...19846533849
distribution of angiostrongylus cantonensis in papua new guinea.examination of 97 rats trapped in port moresby and lae on the mainland of papua new guinea and in rabaul, east new britain province, showed that 12.4% were infected by angiostrongylus cantonensis. larval an. cantonensis were found in achatina fulica snails collected at these towns, from the ramu valley near madang on the mainland and at locations in west new britain, new ireland and bougainville island. the mollusc infection rates ranged from 12.7% at port moresby to 32.4% at kimbe in west new b ...19846533850
effects of catecholamines, monophenolamines and phenylamines on identifiable giant neurons of an african giant snail (achatina fulica férussac).the effects of catecholamines, monophenolamines and phenylamines on eight identifiable giant neurons of an african giant snail (achatina fulica férussac) were examined to classify these neurons into several categories according to their sensitivities to the various substances. the five neurons, pon (periodically oscillating neuron), tan (tonically autoactive neuron), 1-vmn (left-visceral multiple spike neuron), d-rpean (dorsal-right pedal autoactive neuron) and vin (visceral intermittent firing ...19854043218
responses to odors mapped in snail tentacle and brain by [14c]-2-deoxyglucose autoradiography.the method of 2-deoxyglucose (2-dg) autoradiography has been widely used to map functional neuronal systems in vertebrates, but in invertebrate species, where morphological dimensions favor its use, the applications have been minimal. this study uses [14c]-2-dg to map the olfactory system of a terrestrial snail, achatina fulica. the olfactory organ in the snail's tentacles bears a striking resemblance to the vertebrate olfactory mucosa. there are also complex neural structures in the tentacle an ...19854056861
pharmacological characteristics of four giant neurons identified in the cerebral ganglia of an african giant snail (achatina fulica férussac).two giant neurons, d-rcdn (dorsal-right cerebral distinct neuron) and d-lcdn (dorsal left cerebral distinct neuron), with a diameter of about 100 microns, were found symmetrically on the dorsal surface of the cerebral ganglia of an african giant snail (achatina fulica férussac). they showed spontaneous spike discharges at a stable frequency. two giant neurons, v-rcdn (ventral-right cerebral distinct neuron) and v-lcdn (ventral-left cerebral distinct neuron), (diameter, approx. 150 microns) were ...19852858331
pharmacological characteristics of three silent giant neurons, v-lpsn, v-1-vorn and v-vln, identified on the ventral surface in the left parietal and the visceral ganglia of the suboesophageal ganglia of an african giant snail (achatina fulica férussac).three giant neurons, named v-lpsn, v-1-vorn and v-vln, were identified on the ventral surface of the left parietal ganglion and the visceral ganglion in the suboesophageal ganglia of an african giant snail (achatina fulica férussac). they lacked the spontaneous spike discharges in the normal state. the pharmacological features of the three neurons, in relation to the principal common neurotransmitter substances and their derivatives were examined. the v-lpsn (ventral-left parietal silent neuron) ...19852861018
effects of four stereoisomers of beta-hydroxyglutamic acid on identifiable giant neurons of an african giant snail (achatina fulica férussac).the effects of four stereoisomers of beta-hydroxyglutamic acid (erythro-l-bhga, threo-l-bhga, erythro-d-bhga and threo-d-bhga) and glutamic acid (l-glu and d-glu) were compared on six identifiable giant neurons of achatina fulica férussac, namely, pon (periodically oscillating neuron), vin (visceral intermittently firing neuron), d-rpln (dorsal-right parietal large neuron), rapn (right anterior pallial neuron), fan (frequently autoactive neuron) and v-rcdn (ventral-right cerebral distinct neuron ...19852862044
effects of glutamic acid analogues on identifiable giant neurones, sensitive to beta-hydroxy-l-glutamic acid, of an african giant snail (achatina fulica férussac).the effects of the seven glutamic acid analogues, alpha-kainic acid, alpha-allo-kainic acid, domoic acid, erythro-l-tricholomic acid, dl-ibotenic acid, l-quisqualic acid and allo-gamma-hydroxy-l-glutamic acid were examined on six identifiable giant neurones of an african giant snail (achatina fulica férussac). the neurones studied were: pon (periodically oscillating neurone), d-rpln (dorsal-right parietal large neurone), vin (visceral intermittently firing neurone), rapn (right anterior pallial ...19852866005
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