Publications

[a rare case of cysts caused by echinococcus multilocularis of the iliac bone].		1952	14956685
studies on the helminth fauna of alaska. xxx. the occurrence of echinococcus multilocularis leuckart, 1863, on the mainland of alaska.		1956	13381884
studies on the helminth fauna of alaska. xxxi. observations on the propagation of the larval echinococcus multilocularis leuckart, 1863, in vitro.		1957	13406659
observations on the susceptibilities of cotton rats to echinococcus multilocularis (leuckart, 1863).		1957	13439211
[independence of echinococcus multilocularis leuckart, 1863 species].		1958	13558103
[natural foci of echinococcus multilocularis in the novosibirsk region].		1959	13656202
the maintenance of echinococcus multilocularis in gerbils (meriones unguiculatus) by intraperitoneal inoculation.		1961	14480353
the cestode echinococcus multilocularis in foxes in north dakota.		1964	14172624
studies on echinococcosis. xvi. effects of drugs upon scolices and daughter cysts of echinococcus multilocularis in vitro.		1965	5296512
biologic identification of the cestode echinococcus multilocularis isolated from foxes in north dakota.		1965	5861363
[a study of chromosomes of alveococcus multilocularis (echinococcus multilocularis). leuckart, 1863. preliminary report].		1965	5869246
cestode in north dakota: echinococcus in field mice.	field mice (microtus pennsylvanicus and peromyscus maniculatus) are naturally infected with echinococcus multilocularis. thus, the sylvatic cycle (fox to field mice to fox) has been established in north dakota. this cestode is expected to extend its range to other agricultural regions of the continental united states where similar conditions favorable for the completion of its life cycle exist.	1965	5891703
echinococcus multilocularis in a beef cow from the middle west.		1965	14241418
studies on echinococcosis. xvii. sex difference in resistance to infection with echinococcus multilocularis in uniform strains of mice.		1966	5297706
preparation and evaluation of antigens for use in the serologic diagnosis of human hydatid disease. ii. isolation and characterization from extracts of cysts of echinococcus multilocularis of serologically reactive elements found in hydatid fluid of echinococcus granulosus.		1966	4958097
[multilocular pulmonary echinococcosis].		1966	16296046
studies on echinococcosis. xix. heat stable antigen in cystic fluid of echinococcus multilocularis.		1967	4964981
studies on echinococcosis xx. preliminary observations of the in vivo cultivation of larval tissue of echinococcus multilocularis in culture-chamber of porous membrane.		1967	5302682
accelerating growth of a vegetatively propagated strain of larval echinococcus multilocularis (leuck., 1963).		1967	6073490
echinococcus multilocularis in peromyscus maniculatus and vulpes vulpes from minnesota.		1968	5757663
studies on sylvatic echinococcosis. 1. ground beetle transmission of echinococcus multilocularis leuckart, 1863, to deer mice, peromyscus maniculatus (wagner).		1968	5757728
attempts at chemotherapy of echinococcus multilocularis infections in rodents.		1969	5343373
primary pulmonary involvement in rodents infected with echinococcus multilocularis.		1969	5378707
cysts resembling echinococcus multilocularis cysts in a cow in iran.		1969	5394020
cyclophosphamide and the survival time of mice infected with echinococcus multilocularis cysts.		1969	5406766
studies on sylvatic echinococcosis. ii. the occurrence of echinococcus multilocularis leuck. 1863 in manitoba.		1969	5408699
occurrence of echinococcus multilocularis leuckart, 1863 in vulpes fulva in saskatchewan.		1969	5408706
[echinococcus multilocularis].		1970	5528308
the occurrence of echinococcus multilocularis leuckart, 1863 and of other helminths in the red fox, vulpes vulpes, in southern manitoba.		1970	5528607
studies on sylvatic echinococcosis. 3. host occurrence and geographic distribution of echinococcus multilocularis in the north central united states.		1970	5534030
[studies on echinococcosis. 23. electron microscopical observations on histogenesis of larval echinococcus multilocularis].		1970	5313301
[studies on echinococcosis. 23. electron microscopical observations on histogenesis of larval echinococcus multilocularis].		1970	5313479
echinococcus multilocularis leuckart, 1863, in red foxes, vulpes vulpes linn., in moghan, azerbaijan province, northwest of iran.		1971	5090956
the occurrence of echinococcus multilocularis (leukart, 1863) in cats near saskatoon, saskatchewan.		1971	5104959
the occurrence of echinococcus multilocularis leuckart, 1863 in alberta.		1971	5106581
attempts at chemotherapy of echinococcus multilocularis infections in rodents. ii. a study of some parasiticides and cytostatic agents.		1971	5119811
observations on parasite-host relationships of echinococcus multilocularis leuckart, 1863, in north dakota.		1971	5119812
echinococcus multilocularis in the cotton rat. asexual proliferation following the intraperitoneal inoculation of graded doses of protoscolices.		1972	5055120
plain film roentgenographic findings in alveolar hydatid disease--echinococcus multilocularis.		1972	5078858
[development of secondary echinococcus multilocularis in the experimentally infected mouse. a quantitative analysis].		1972	4634259
[a quantitative study of the production of calcareous corpuscles by echinococcus multilocularis in the experimentally infected mouse].		1972	4634260
echinococcus multilocularis: a possible domestic life cycle in central north america and its public health implications.		1972	4641897
[preparation of inoculum for the intraperitoneal infection of the mouse with echinococcus multilocularis].		1972	4650091
studies on echinococcosis. xxiv. age difference in resistance to infection with echinococcus multilocularis in akr strain of mouse.		1972	4540106
studies on echinococcosis. xxv. anthelmintic action of drugs on larval echinococcus multilocularis in vitro.		1973	4543534
rearing of the adult echinococcus multilocularis leuckart, 1863, from sterile larvae from man.		1973	4574754
echinococcus multilocularis in the cotton rat. the effect of preexisting subcutaneous cysts on the development of a subsequent intraperitoneal inoculum of protoscolices.		1973	4696081
[echinococcus multilocularis infection and antibody titer in intraperitoneally and subcutaneously infected mice (author's transl)].		1973	4743771
[development of protoscolices of echinococcus multilocularis in experimentally infected mice in dependence on age and sex of the experimental animals and on infection --prerequisites for the development of a test model].		1973	4145882
[formation of calcareous corpuscles due to echinococcus multilocularis in experimentally infected mice in dependence of age and sex of the animal and of infection dose--prerequisites for the development of a test model].		1973	4145883
host-parasite relationship in echinococcosis. i. parasite biomass and antibody response in three strains of inbred mice against graded doses of echinococcus multilocularis cysts.		1974	4206878
echinococcus multilocularis leuckart, 1863 in rodents in southern alberta.		1974	4422509
treatment of the cystic stage of taenia crassiceps and echinococcus multilocularis in laboratory animals.		1974	4436750
[susceptibility of golden hamsters to infection with larval echinococcus multilocularis (author's transl)].		1974	4471924
growth of secondary echinococcus multilocularis in experimentally infected hosts.		1974	4840652
studies on sylvatic echinococcosis. iv. ecology of echinococcus multilocularis in the intermediate host, peromyscus maniculatus, in north dakota, 1965-1972.		1974	4847041
resistance of echinococcus multilocularis to x-ray.		1974	4854127
host-parasite relationship in echinococcosis. ii. cyst weight, hematologic alterations, and gross changes in the spleen and lymph nodes of c57l mice against graded doses of echinococcus multilocularis cysts.		1974	4855510
comparison of yearly prevalences of echinococcus multilocularis leuckart 1863 in peromyscus maniculatus and microtus pennsylvanicus in north dakota.		1975	1104799
in vitro suppression of segmentation in echinococcus multilocularis with morphological transformation of protoscoleces into monozoic adults.	when protoscoleces of echinococcus multilocularis were cultured in vitro, under axenic conditions in either monophasic or diphasic media, segmentation was suppressed in most organisms, some 70-80% of which developed into unsegmented, monozoic forms with a complete set of sexually mature male and female genitalia. the most striking feature of monozoic worms was the large lateral swelling produced by the cirrus sac the effect being to produce organisms with an unusual asymmetric shape. worms which ...	1975	1178218
effect of parenterally injected benzimidazole compounds on echinococcus multilocularis and taenia crassiceps metacestodes in laboratory animals.	in mice infected with metacestodes of taenia crassiceps, the following compounds were at least partially effective when injected intraperitoneally at the dosage indicated: cambendazole (500 mg/kg), mebendazole (6.25 mg/kg), oxibendazole (500 mg/kg), 5-benzamido-2(4-thiazolyl)benzimidazole (500 mg/kg), 2-carboethoxyamino benzimidazole (125 mg/kg), and 2-carbomethoxyamino benzimidazole (500 mg/kg). the following were inactive at the dosage indicated: parbendazole (500 mg/kg), thiabendazole (1,000 ...	1975	1242396
[echinococcus multilocularis causing extensive biliary obstruction (author's transl)].	infection of man by echinococcus multilocularis occurs relatively seldom, most commonly localizing in the liver in the manner of a malignant tumour. a case of alveolar hydatid disease is reported presenting with extensive biliary obstruction, and a large cavitation in the liver due to necrosis. a review of epidemiology, clinical and roentgenological findings is given.	1975	49287
echinococcus multilocularis in the cotton rat: growth of intrathoracic metastases following surgical removal of subcutaneous cysts.		1976	1262126
echinococcus multilocularis in the cotton rat: the in vitro protoscolicidal activity of peritoneal cells.		1976	1279074
lesions induced by complement in vitro on the protoscoleces of echinococcus multilocularis: a study by electron microscopy.		1976	1279075
preliminary identification and characterization of antigen extracts from onchocerca volvulus.	sequential extraction of onchocerca volvulus from skin nodules with buffers of different ionic strength resulted in a mixture of antigens which reacted in double immunodiffusion with sera from proven cases of onchocerciasis, the number of precipitation lines varied from 1 to 5. triton x-100 detached mainly cationic antigen proteins. it reduced the molecular size of many antigenic proteins, but did not effect their antigenicity. labelling of the extracted proteins with high specific activity 125i ...	1976	824771
[on the effect of mebendazole on metacestodes of mesocestoides corti and echinococcus multilocularis (author's transl)].	mebendazole (5-benzoyl-2-methoxycarbonylaminobenzimidazole) was highly effective against tetrathydridia of mesocestoides corti in the peritoneal cavity, liver and in the subcutis of mice when administered orally in the food (450 or 465 ppm) from days 7 or 40/50 post infectionem (p.i.) for 10 or 20 days in total doses of approximately 660-1660 mg/kg body weight (b.w.). all tetrathyridia were killed when treatment began at day 7 p.i., and only some survived when medication was started on days 40/5 ...	1976	988654
[scanning electron microscope studies of echinococcus multilocularis cysts (author's transl)].	in the present paper, morphologic studies on experimental echinococcosis are reported. following i.p. infection of gerbils (meriones unguiculatus) with echinococcus multilocularis scolices, the development of cysts within the internal organs of the experimental animals could be readily visualized by scanning electron microscopy.	1976	1016476
the effect of immunosuppression on secondary echinococcus multilocularis infections in mice.		1976	1082860
host serum proteins in echinococcus multilocularis: complement activation via the classical pathway.	the presence of host serum proteins, including igg and igm, within the cyst membranes and on the surface of protoscoleces of echinococcus multilocularis was demonstrated by the use of hrpo-conjugated purified antisera. viable protoscoleces incubated either in edta- or egta-fresh human sera were not lysed; the addition of calcium restored the protoscolecidal activity of the egta serum. it is concluded that the complement-mediated lysis of this metazoan organism proceeds via the classical pathway ...	1977	873569
the natural occurrence of echinococcus multilocularis in the bushy-tailed woodrat, neotoma cinerea rupicola, in wyoming.	echinococcus multilocularis leuckart, 1863, is reported from neotoma cinerea rupicola allen in wyoming. this report represents new host and locality records for the cestode. the larva had undergone active multilocular vesiculation in the liver with minimal host-tissue reaction. protoscolices and calcareous corpuscles were absent.	1977	907044
echinococcus multilocularis in the mouse: the in vitro protoscolicidal activity of peritoneal macrophages.		1977	340398
echinococcus multilocularis: complement's role in vivo in hydatid disease.		1977	598449
[on echinococcus multilocularis in southern germany ii. development of the larval stages and histopathological reactions in common vole, microtus arvalis (author's transl)].		1977	601851
evaluation of the indirect haemagglutination and intradermal tests on hydatid and nonhydatid cases.	evaluation of the immediate intradermal (id) test showed a direct relationship between nitrogen concentration and sensitivity. antigens of low nitrogen concentration were less reactive but more specific. intradermal antigens prepared from echinococcus multilocularis can be used in isfahan, iran, for the diagnosis of e. granulosus in man. the id delayed reaction was observed in a few patients who had positive immediate skin tests. because of its high sensitivity, the indirect haemagglutination (i ...	1977	610023
cellular changes in the lymphoreticular tissues of c57l/j mice infected with echinococcus multilocularis cysts.	the pathology of the spleen, lymph nodes and thymus of c57l/j mice, infected intraperitoneally with 20 and 100 cysts of echinococcus multilocularis is described at 2, 4, 8 and 12 weeks postinfection (p.i.). for the first 8 weeks, growth of the larval cyst mass (lcm) was slow and blastogenesis in t-dependent areas of both spleen and lymph nodes was moderate whereas in b-cell compartments it was intense. a rapid growth of the lcm between 8 and 12 weeks p.i., 15-20 times greater than for the first ...	1978	658980
studies on sylvatic echinococcosis. v. factors influencing prevalence of echinococcus multilocularis leuckart 1863, in red foxes from north dakota, 1965--1972.	a total of 1,153 red foxes, vulpes vulpes, was examined for strobilae of echinococcus multilocularis from 2 geographic regions in north dakota during 1965 through 1972. echinococcus multilocularis was found in 184 (16%) of these foxes. the data including date and location of collection, age and sex of the host, and presence or absence of the cestode were used to assess the relative influence of collection interval (sampling period), climatic season, geographic location, and age and sex of the ho ...	1978	682065
[fenbendazole therapy of experimental larval echinococcosis. i. the effect of fenbendazole on worm burden and protoscolex development of echinococcus multilocularis (author's transl)].	application of fenbendazole (methyl-5-(phenyl-thio)-benzimidazole-2-carbamate) in echinococcus multilocularis infected mice showed a significant efficiency on the development of the cysts; the worm burden and the number of protoscolices were significantly reduced in the treated animals in comparison with the non-treated control mice. the degree of efficiency was subject to the way of application, the duration of medication, and the parasite strain: 1. on application of f. as medicated feed (500 ...	1978	696062
a clinical trial of mebendazole in the treatment of alveolar hydatid disease.	in july 1974, mebendazole was reported to be effective against the larval stage of echinococcus granulosus in experimentally infected mice. a clinical trial of mebendazole was initiated in december 1974 in 4 patients with far advanced, nonresectable lesions caused by echinococcus multilocularis. a daily dose of 40 mg of the drug per kg of body weight was administered to the 4 patients for more than 3 years. no evidence of toxicity or adverse reactions has been observed. detectable plasma mebenda ...	1978	707895
immunoprophylaxis with bcg of experimental echinococcus multilocularis infections.	previous studies have demonstrated that prophylactic treatment with bcg protects cotton rats (sigmodon hispidus) against experimental infections with echinococcus multilocularis; this treatment can, however, induce granulomatous reactions. in an attempt to identify a minimum prophylactic dose of bcg which would not induce granulomas, cotton rats were treated intraperitoneally with various doses of bcg (10(1) to 10(7) colony-forming units [cfu]) and then inoculated intraperitoneally with one broo ...	1978	711311
echinococcus multilocularis: cell-mediated immune response in early and chronic alveolar murine hydatidosis.		1978	729696
echinococcus multilocoularis infection in india: first case report proved at autopsy.	the occurrence of echinococcus multilocularis is reported in india for the first time. the patient was a young man, various clinical diagnoses were made and he finally died after an attempted membranotomy for suspected membranous obstruction in the inferior vena cava. autopsy revealed classical e. multilocularis infection of the liver with direct spread of the inferior vena cava, the right atrium and through the diaphragm into the base of the left lung. it also had caused an outflow tract obstru ...	1978	734718
visceral larva migrans and alveolar hydatid disease. dangers real or imagined.	for both visceral larva migrans and alveolar hydatid diseases, it is the feces of companion animals that are the primary source of human infection. clearly, whatever is done to reduce this form of environmental contamination and the prevalence of the parasites' infective stages will help to protect the health of the human population in the united states and canada, particularly the children. very important are appropriate anthelmintic treatment programs, especially for t. canis, and proper contr ...	1978	356405
[the indirect immunofluorescent antibody test with paraffin-embedded histological sections as antigen in experimental echinococcosis (author's transl)].	a modification of the indirect immunofluorescent antibody test for the diagnosis of infections with metacestodes of echinococcus multilocularis is described. formol alcohol was used as fixative mixture for the antigen materials; as embeding medium served paraffin. in positive reactions the peripheral protoscolex-layers showed a bright yellow-green fluorescence. specificity and sensibility in the animal model experiment are to be expressed as very good.	1978	364798
[fenbendazole therapy of experimental larval echinococcosis. 3. the antibody titer in the indirect immunofluorescent test (author's transl)].	echinococcus multilocularis-infected nmri-mice treated with fenbendazole show a lower antibody titer in the immuno-fluorescence test than the untreated controls. between animals, which were infected with different parasite strains, also differences in the antibody titer are to be seen. the same applies to animals, which were dissected at different times p.i. as well: with increasing duration of the infection it was observed a higher titer. the mentioned differences are chiefly due to the close p ...	1978	367008
[the efficacy of praziquantel against experimental cysticercosis and hydatidosis (author's transl)].	praziquantel is active against cysticerci in experimentally infected mice, rabbits, sheep and cattle. after single or repeated application the infectious stages of hymenolepis nana, cysticercus fasciolaris, c. pisiformis, c. tennuicollis and c. bovis were killed. the compound is more active against older than against younger stages as demonstrated with h. nana-cystecercoids and c. fasciolaris in mice. against the tetrahyridia of mesocestoides corti in mice praziquantel is only effective after an ...	1978	417482
the efficacy of praziquantel against cestodes in cats, dogs and sheep.	praziquantel is a new type of acylated isoquinoline-pyrazine. a single, low oral or subcutaneous dose of the compound is reliably effective against all tested juvenile and adult cestodes in cats, dogs and sheep. praziquantel is the first cestodicide which is also effective on bile duct cestodes. in cats and dogs, 5 mg praziquantel per kg is completely effective on all stages of taenia hydatigena, t pisiformis, t ovis, t taeniaeformis, dipylidium caninum, mesocestoides corti, echinococcus multilo ...	1978	564542
the muskrat as an intermediate host of echinococcus multilocularis in montana.		1979	448595
some intestinal parasites of arctic fox, banks island, n. w. t.	small intestinal parasitology of 50 trapped arctic fox taken on banks island, the northwest territories, showed a prevalence of taenia crassiceps (78%), toxascaris leonina (60%), echinococcus multilocularis (2%) and coccidia (2%). attention is drawn to the absence of toxocara sp. and of uncinaria sp.	1979	497890
case report of echinococcus multilocularis infection from the mid-western province of japan.		1979	536120
[echinococcus multilocularis: superinfections in experimentally infected mice (author's transl)].	the influence of subcutaneous superinfections following an intraperitoneal primary infection after 4 and 14 weeks respectively has been examined in echinococcus multiolcularis infected nmri-mice. it could be shown that the growth of subcutaneous echinococci is inhibited in superinfected mice (372 mg) if compared with control mice (903 mg parasite weight). other differences (composition of serum proteins and white blood cells, hemoglobin content) are exclusively due to the primary intraperitoneal ...	1979	543004
the effect of praziquantel on hymenolepis diminuta in vitro.	qualitative observations were made on hymenolepis diminuta, h. microstoma, h. nana and pre-adult echinococcus multilocularis in vitro. a dose as low as 0.0001 microgram praziquantel/ml affects the tapeworms, while concentrations of 0.01 - 0.1 and 1-10 microgram/ml cause contraction and paralysis in the contracted state within 10 min and 10-30 s, respectively. the in vitro effects of praziquantel on hymenolepis diminuta have been studied using anaerobic and aerobic incubations and media containin ...	1979	543005
protection of cotton rats against experimental echinococcus multilocularis infections with bcg cell walls.	previous works has indicated that cotton rats treated with mycobacterium bovis strain bcg are effectively protected against an infection with the metastatically proliferating metacestodes of echinococcus multilocularis. in an attempt to induce a similar protection in the absence of tubercular granulomatous lesions, cotton rats were treated with bcg cell walls. a single injection of 150 micrograms of cell walls, emulsified in mineral oil-tween-saline, 2 weeks before the inoculation of the parasit ...	1979	378829
humoral response to sheep red blood cells in c57l/j mice during early and chronic stages of infection with echinococcus multilocularis cysts.	c57l/j male mice infected with echinococcus multilocularis cysts were challenged intraperitoneally at 4, 8, and 12 weeks postinfection (p.i.) with 3 x 10(9) sheep erythrocytes. the direct plaque forming cells, 2-mercaptoethanol (2-me) sensitive (4-day sera) and 2-me-resistant (8-day sera) haemagglutinin responses were significantly elevated at eight and 12 weeks p.i. as compared to controls or the fourweeks postinfected mice. possible mechanisms of immunopotentiation in the chronically infected ...	1979	395785
alveolar hydatid disease in minnesota. first human case acquired in the contiguous united states.	a 56-year-old woman from southwestern minnesota underwent an extended left hepatic lobectomy to remove a large multinodular mass with a necrotic central cavity. the clinical, serological, and pathological findings led to the diagnosis of alveolar hydatid disease, and specific identification of echinococcus multilocularis was achieved by growing mature larvas in voles inoculated intraperitoneally with tissue from the hepatic lesions. the patient probably acquired her infection some years previous ...	1979	762867
[the sunken drain for internal biliary tract drainage (author's transl)].	in over 4000 interventions on the biliary tract a sunken drain was inserted in 35 patients: 3 times because of carcinomatous infiltration from outside, 27 times because of a proximal hepatic carcinoma and 5 times because of echinococcus multilocularis. the postoperative mortality was 8.5%. follow-up examinations show that a little more than a quarter of carcinoma patients died of the primary disease within 6 months but also that 5 patients survived their serious cancer disease for up to 2 1/2 ye ...	1980	6772897
[experimental echinococcus multilocularis infections of the maternal mouse and their significance for the offspring].	experimental infection of mother mice by intraperitoneal injection of echinococcus multilocularis cyst material does not result in the transfer of protective immunity to the offspring. in the contrary, if infected via the same route, filial mice show a lower antibody titer, when examined 36, 78 and 120 days p.i. and a higher worm burden (average: 1455 mg) in comparison with control mice born of non-infected mothers (average parasite weight: 844 mg). the question is discussed, whether these obser ...	1980	6998062
alveolar hydatid disease of the liver with budd-chiari syndrome.	alveolar hydatid disease in man is the intermediate stage in the life cycle of the tapeworm echinococcus multilocularis. this is a rare disease restricted to very few areas of the world. the occurrence of this disease in india is now described for (so far as the authors are aware) the first time. some unusual features of the disease are highlighted in this patient. the hepatic lesion had infiltrated into the right atrial wall resembling an atrial tumour. the ostium of the inferior vena cava was ...	1980	7393812
is alveolar hydatid disease of the liver incurable?	the etiologic agent of alveolar hydatid disease is echinococcus multilocularis. infestation of the liver by the larvae of this cestode results in an infiltrative mass that behaves biologically very much like a malignant tumor. from 1955 to 1978, 13 patients with alveolar hydatid disease of the liver were investigated, operated and followed at the university medical center of lausanne, switzerland. due to the extension of the lesions, six patients had exploratory laparotomy with biopsy only; the ...	1980	7406556
pathogenesis and host response in subcutaneous alveolar hydatidosis. i. histogenesis of alveolar cyst and a qualitative analysis of the inflammatory infiltrates.	c57l/j male mice were infected subcutaneously in their left flank with 10 cysts of echinococcus multilocularis. the dimensions and histologic features of the larval cyst mass (lcm) were determined at three days, at weekly intervals for 12 weeks, and at 22 weeks postinfection. the lcm doubled its size between 3 and 12 weeks, and at 22 weeks it was five times larger than at three weeks. during the proliferative phase, the lcm was infiltrated massively by neutrophils, macrophages, and progenitors o ...	1980	7415417