Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| the utility of plasmodium berghei as a rodent model for anti-merozoite malaria vaccine assessment. | rodent malaria species plasmodium yoelii and p. chabaudi have been widely used to validate vaccine approaches targeting blood-stage merozoite antigens. however, increasing data suggest the p. berghei rodent malaria may be able to circumvent vaccine-induced anti-merozoite responses. here we confirm a failure to protect against p. berghei, despite successful antibody induction against leading merozoite antigens using protein-in-adjuvant or viral vectored vaccine delivery. no subunit vaccine approa ... | 0 | 23609325 |
| systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points. | haematopoiesis is the complex developmental process that maintains the turnover of all blood cell lineages. it critically depends on the correct functioning of rare, quiescent haematopoietic stem cells (hscs) and more numerous, hsc-derived, highly proliferative and differentiating haematopoietic progenitor cells (hpcs). infection is known to affect hscs, with severe and chronic inflammatory stimuli leading to stem cell pool depletion, while acute, non-lethal infections exert transient and even p ... | 0 | 27335321 |
| transmission-blocking interventions eliminate malaria from laboratory populations. | transmission-blocking interventions aim to reduce the prevalence of infection in endemic communities by targeting plasmodium within the insect host. although many studies have reported the successful reduction of infection in the mosquito vector, direct evidence that there is an onward reduction in infection in the vertebrate host is lacking. here we report the first experiments using a population, transmission-based study of plasmodium berghei in anopheles stephensi to assess the impact of a tr ... | 0 | 23652000 |
| a tetracycline-repressible transactivator system to study essential genes in malaria parasites. | a major obstacle in analyzing gene function in apicomplexan parasites is the absence of a practical regulatable expression system. here, we identified functional transcriptional activation domains within apicomplexan ap2 (apiap2) family transcription factors. these apiap2 transactivation domains were validated in blood-, liver-, and mosquito-stage parasites and used to create a robust conditional expression system for stage-specific, tetracycline-dependent gene regulation in toxoplasma gondii, p ... | 0 | 23245327 |
| hiv nonnucleoside reverse transcriptase inhibitors and trimethoprim-sulfamethoxazole inhibit plasmodium liver stages. | although nonnucleoside reverse transcriptase inhibitors (nnrtis) are usually part of first-line treatment regimens for human immunodeficiency virus (hiv), their activity on plasmodium liver stages remains unexplored. additionally, trimethoprim-sulfamethoxazole (tmp-smx), used for opportunistic infection prophylaxis in hiv-exposed infants and hiv-infected patients, reduces clinical episodes of malaria; however, tmp-smx effect on plasmodium liver stages requires further study. | 0 | 23125449 |
| a plasmodium calcium-dependent protein kinase controls zygote development and transmission by translationally activating repressed mrnas. | calcium-dependent protein kinases (cdpks) play key regulatory roles in the life cycle of the malaria parasite, but in many cases their precise molecular functions are unknown. using the rodent malaria parasite plasmodium berghei, we show that cdpk1, which is known to be essential in the asexual blood stage of the parasite, is expressed in all life stages and is indispensable during the sexual mosquito life-cycle stages. knockdown of cdpk1 in sexual stages resulted in developmentally arrested par ... | 0 | 22817984 |
| long-term live imaging reveals cytosolic immune responses of host hepatocytes against plasmodium infection and parasite escape mechanisms. | plasmodium parasites are transmitted by anopheles mosquitoes to the mammalian host and actively infect hepatocytes after passive transport in the bloodstream to the liver. in their target host hepatocyte, parasites reside within a parasitophorous vacuole (pv). in the present study it was shown that the parasitophorous vacuole membrane (pvm) can be targeted by autophagy marker proteins lc3, ubiquitin, and sqstm1/p62 as well as by lysosomes in a process resembling selective autophagy. the dynamics ... | 0 | 26208778 |
| evaluation of antiplasmodial activity of extracts and constituents from ampelozizyphus amazonicus. | ampelozizyphus amazonicus ducke, a plant that is widely used by the population of the amazonian region to prevent and treat malaria, was investigated in this work, which describes, for the first time, the antiplasmodial activity of its extracts and associates this activity with its isolated constituents. | 0 | 26664012 |
| genome-wide functional analysis of plasmodium protein phosphatases reveals key regulators of parasite development and differentiation. | reversible protein phosphorylation regulated by kinases and phosphatases controls many cellular processes. although essential functions for the malaria parasite kinome have been reported, the roles of most protein phosphatases (pps) during plasmodium development are unknown. we report a functional analysis of the plasmodium berghei protein phosphatome, which exhibits high conservation with the p. falciparum phosphatome and comprises 30 predicted pps with differential and distinct expression patt ... | 0 | 25011111 |
| quantification of sporozoite invasion, migration, and development by microscopy and flow cytometry. | there is an important role for in vitro assays to better understand the initial steps of malaria infection. in this section, we describe both microscopy-based and flow cytometry-based sporozoite invasion, migration and development assays with the rodent malaria parasites, plasmodium berghei and plasmodium yoelii, and the human malaria parasite, plasmodium falciparum. | 0 | 22990793 |
| in vitro and in vivo antimalarial activity and cytotoxicity of extracts, fractions and a substance isolated from the amazonian plant tachia grandiflora (gentianaceae). | tachia sp. are used as antimalarials in the amazon region and in vivo antimalarial activity of a tachia sp. has been previously reported. tachia grandiflora maguire and weaver is an amazonian antimalarial plant and herein its cytotoxicity and antimalarial activity were investigated. spectral analysis of the tetraoxygenated xanthone decussatin and the iridoid aglyone amplexine isolated, respectively, from the chloroform fractions of root methanol and leaf ethanol extracts was performed. in vitro ... | 0 | 23827996 |
| [not available]. | 1948 | 18874862 | |
| response of plasmodium berghei to antimalarial drugs. | 1949 | 15398092 | |
| [tissular phase of plasmodium berghei]. | 1950 | 15413859 | |
| [effect of splenectomy on the evolution and relapse of plasmodium berghei vincke and lips infection in the white rat]. | 1950 | 15435003 | |
| [on the virulence of plasmodium berghei, hemosporidia of a rodent of central africa to the north african rodent meriones shawi]. | 1950 | 14800475 | |
| [cyclic transmission of plasmodium berghei]. | 1950 | 14830042 | |
| studies on plasmodium berghei n. sp. vincke and lips, 1948. i. variations in susceptibility in albino mice. | 1950 | 14880187 | |
| studies on plasmodium berghei n. sp. vincke and lips, 1948, ii. morphology, periodicity and pathogenicity in blood induced infections in mice, rats and garden squirrels. | 1950 | 14880188 | |
| the action of antimalarial drugs in mice infected with plasmodium berghei. | 1950 | 14777864 | |
| behaviour of plasmodium berghei in some rodents. | 1950 | 14780155 | |
| [behavior of roussettus leachi toward plasmodium berghei]. | 1950 | 14800009 | |
| the schizonticidal effect of some antimalarials against plasmodium berghei. | 1950 | 24538832 | |
| susceptibility of the indian garden squirrel (sciurus palmarum) to plasmodium berghei and its asexual periodicity. | 1951 | 14826832 | |
| [the effect of chemotherapeutic agents on plasmodium berghei vincke & lips]. | 1951 | 14837159 | |
| [plasmodium berghei infection in the white rat]. | 1951 | 14839468 | |
| [behavior of cotton rat towards plasmodium berghei; complementary note]. | 1951 | 14847384 | |
| [experiment in development of plasmodium berghei, vincke and lips in anopheles maculipennis (var. atroparvus)]. | 1951 | 14847385 | |
| morphological changes in plasmodium berghei following proguanil, sulphadiazine and mepacrine therapy. | 1951 | 14855618 | |
| [behavior of reinoculation hematozoa in the blood of rats cured of plasmodium berghei infection]. | 1951 | 14870381 | |
| the course of the blood-induced plasmodium berghei infection in white mice. | 1951 | 14889386 | |
| [peculiar immunity phenomena in plasmodium berghei infection]. | 1951 | 14892299 | |
| [relation between plasmodium berghei and erythrocytes during the primary attack in the white rat]. | 1951 | 14892300 | |
| [factors and significance of the prepatent period in experimental plasmodium berghei malaria]. | 1951 | 14905222 | |
| [effect of splenectomy on white rats spontaneously recovered from experimental infection with plasmodium berghei]. | 1951 | 14905661 | |
| [serologic study of experimental infection of the white rat with plasmodium berghei; disappearance of alexin. presence of complement fixing antibodies]. | 1951 | 14905662 | |
| [trans cutaneous infection of newborn rats and mice with plasmodium berghei]. | 1951 | 14905669 | |
| [study of the different routes of experimental inoculation of plasmodium berghei in albino rats and mice]. | 1951 | 14905670 | |
| [production of congenital malaria in the rat and mouse by placental passage of plasmodium berghei]. | 1951 | 14905671 | |
| [serological study of experimental plasmodium berghei infection in white rat; quantitative variations of sensitizor and alexin during the disease]. | 1951 | 14905723 | |
| the course of the blood-induced plasmodium berghei infection in white rats. | 1951 | 14908565 | |
| complete sporogenic development of plasmodium berghei in experimentally infected anopheles spp. | 1951 | 14910642 | |
| parasitic recrudescences in trophozoite-induced plasmodium berghei infections in the albino rat. | 1951 | 14915458 | |
| pathological processes in disease. iii. the oxygen uptake of blood from albino rats infected with plasmodium berghei. | 1951 | 14915463 | |
| [intracardiac inoculation of plasmodium berghei; technique and evaluation of method]. | 1951 | 14926172 | |
| [intracardiac reinoculation with plasmodium berghei in rats recovered from prior infection]. | 1951 | 14926173 | |
| [massive, intraperitoneal inoculation with plasmodium berghei in white rats]. | 1951 | 14926174 | |
| the effect of splenectomy on the course of plasmodium berghei infections in microtus guentheri. | 1951 | 14873942 | |
| the effect of neoarsphenamine on plasmodium berghei infections in the mouse and rat: inhibition of the antimalarial action of neoarsphenamine by british anti-lewisite. | 1951 | 14878394 | |
| [experimental plasmodium berghei infection of the rabbit]. | 1951 | 14905184 | |
| [sensibility of the golden hamster to plasmodium berghei vincke and lips 1948]. | 1951 | 14839860 | |
| [on the long duration of latent metacritic infection in experimental malaria of plasmodium berghei in north african meriones]. | 1951 | 14934327 | |
| [innate resistance of guinea pig to plasmodium berghei malaria of rodents]. | 1951 | 14934328 | |
| studies on plasmodium berghei n. sp. vincke and lips, 1948. iii. latency, relapse and immunity in albino rats with blood-induced infections. | 1951 | 14955278 | |
| studies on plasmodium berghei n. sp. vincke and lips, 1948. iv. the reaction of blood-induced p. berghei in albino mice to quinine and sulphadiazine. | 1951 | 14955279 | |
| [therapy of plasmodium berghei infection in the rat]. | 1951 | 13028080 | |
| [massive injection of plasmodium berghei into rat, for determination of effectiveness of an antimalarial; nivaquine]. | 1952 | 13020089 | |
| [serological study of experimental plasmodium berghei infection in white rat; sandor's reticuloendothelial record and euglobuline i1]. | 1952 | 13020090 | |
| [relations between blood reticulocytosis and the infection of a white rat with plasmodium berghei]. | 1952 | 13020258 | |
| [plasmodium berghei (vincke & lips) infection]. | 1952 | 13028089 | |
| [note on the morphology of plasmodium berghei vincke and lips observed by phase contrast microscope]. | 1952 | 13032762 | |
| studies on plasmodium berghei n. sp. vincke and lips, 1948. | 1952 | 13044278 | |
| studies on plasmodium berghei n. sp. vincke and lips, 1948. vi. reaction of blood-induced infection in albino mice to daraprim 2:4-diamino pyrimidine. | 1952 | 13044279 | |
| studies on plasmodium berghei n. sp. vincke and lips, 1948. vii. spleen size in albino mice and rats with blood-induced infections. | 1952 | 13044280 | |
| [value of the blood reticulocyte level in experimental malaria in white rats caused by plasmodium berghei]. | 1952 | 13009915 | |
| [quantitative and qualitative study of the blood parasites during an experimental infection of white rats with plasmodium berghei]. | 1952 | 12976787 | |
| [plasmodium berghei vincke and lips 1948; experimental study of malaria in rodents]. | 1952 | 12981439 | |
| [plasmodium berghei vincke]. | 1952 | 12982288 | |
| a microchemical study of plasmodium berghei by microincineration, with a note on the microscopical demonstration of calcium. | 1952 | 12986696 | |
| the absorption of inoculated blood containing plasmodium berghei from the peritoneal cavity of the mouse. | 1952 | 12986700 | |
| [resistance of plasmodium berghei at low temperatures]. | 1952 | 12987999 | |
| [experimental plasmodium berghei malaria in the white rat]. | 1952 | 12988010 | |
| [demonstration and analysis of crossed immunity between two strains of plasmodium berghei]. | 1952 | 12988447 | |
| [results of the intracardiac or intraperitoneal injection in white mouse of large quantities of erythrocytes parasited with plasmodium berghei]. | 1952 | 12988448 | |
| [study in the white rat of the relations between vitamin a deficiency and experimental malaria with plasmodium berghei]. | 1952 | 12988449 | |
| the effect of antibiotics on experimental malaria (plasmodium cathemerium and plasmodium berghei). | 1952 | 12996741 | |
| blood sugar studies on the white rat infected with plasmodium berghei. | 1952 | 12996742 | |
| [the thorn test in experimental plasmodium berghei malaria in white rat]. | 1952 | 13020087 | |
| [effect of adrenalectomy on experimental plasmodium berghei malaria in white rat]. | 1952 | 13020088 | |
| cyclical transmission of plasmodium berghei in the laboratory. | 1952 | 14941077 | |
| [the possibility of preserving trypanosoma congolense and plasmodium berghei at -70 degrees c]. | 1952 | 14945110 | |
| synergistic effect of haemobartonella muris on plasmodium berghei in white rats. | 1952 | 14952697 | |
| [the development of plasmodium berghei in the atroparvus variant of anopheles maculipennis]. | 1952 | 14953087 | |
| cortisone and plasmodium berghei infection in mice. | 1952 | 14929234 | |
| studies on plasmodium berghei n sp. vincke and lips, 1948. | 1953 | 13117524 | |
| studies on plasmodium berghei n.sp. vincke and lips, 1948. xii. attempts to estimate in vivo the acquired immunity in albino rats. | 1953 | 13117525 | |
| the course of the blood-induced plasmodium berghei infection in the meadow mouse microtus pennsylvanicus and certain other small rodents. | 1953 | 13007920 | |
| [the influence of strain, sex and age of mice on infection with plasmodium berghei]. | 1953 | 13069774 | |
| residual immunity following radical cure of plasmodium berghei in intact and splenectomized voles (microtus guentheri). | 1953 | 13061766 | |
| development of plasmodium berghei in anopheles quadrimaculatus. | 1953 | 13065628 | |
| studies on the nucleic acids of the malaria parasite, plasmodium berghei; vincke & lips. | 1953 | 13066388 | |
| the action of dyes, antibiotics, and some miscellaneous compounds against plasmodium berghei. | 1953 | 13066715 | |
| the morphology of plasmodium berghei before and after treatment with drugs. | 1953 | 13077728 | |
| [neutralizing effects of pituitary growth hormone in plasmodium berghei infections in mice]. | 1953 | 13082813 | |
| [receptivity of african flying-foxes to plasmodium berghei vincke et lips]. | 1953 | 13094452 | |
| [parasitological and experimental study of plasmodium berghei vincke and lips, 1948]. | 1953 | 13098708 | |
| [effect of milk diet on infections by plasmodium berghei, plasmodium vinckei and babesia rodhaini in mice]. | 1953 | 13105095 | |
| [evolution of plasmodium berghei and p. vinckei in different mammals]. | 1953 | 13105097 | |
| acute hepatitis associated with mouse leukemia. iv. the relationship of eperythrozoon coccoides to the hepatitis virus of princeton mice. | the hepatitis of princeton weanlings was not prevented by the prior injection of terramycin nor was the virus inactivated by exposure to room temperature. eperythrozoon coccoides was not demonstrable in blood films from swiss and princeton mice infected with the corresponding type of hepatitis virus. combined infection with this virus and eperythrozoa, originally obtained by dr. r. b. mcghee from mice in association with plasmodium berghei, was attended by the appearance of numerous organisms in ... | 1953 | 13109101 |
| [parasitologic and experimental studies on plasmodium berghei vincke and lips, 1948]. | 1953 | 13110558 |