Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| dna vaccines targeting heavy chain c-terminal fragments of clostridium botulinum neurotoxin serotypes a, b, and e induce potent humoral and cellular immunity and provide protection from lethal toxin challenge. | botulinum neurotoxins (bonts) are deadly, toxic proteins produced by the bacterium clostridium botulinum that can cause significant diseases in humans. the use of the toxic substances as potential bioweapons has raised concerns by the centers for disease control and prevention and the united states military. currently, there is no licensed vaccine to prevent botulinum intoxication. here we present an immunogenicity study to evaluate the efficacy of novel monovalent vaccines and a trivalent cockt ... | 0 | 26158319 |
| intestinal toxemia botulism in 3 adults, ontario, canada, 2006-2008. | five cases of intestinal toxemia botulism in adults were identified within an 18-month period in or near toronto, ontario, canada. we describe findings for 3 of the 5 case-patients. clinical samples contained clostridium botulinum spores and botulinum neurotoxins (types a and b) for extended periods (range 41-61 days), indicative of intestinal toxemia botulism. patients' clinical signs improved with supportive care and administration of botulinum antitoxin. peanut butter from the residence of 1 ... | 0 | 22257757 |
| methods for the isolation and cultivation of bacillus putrificus and other obligate anaerobes. | 1919 | 16558831 | |
| the occurrence of bacillus botulinus in nature. | 1919 | 16558851 | |
| notes on bacillus botulinus. | 1919 | 16558852 | |
| the influence of various chemical and physical agencies upon bacillus botulinus and its spores: i. resistance to salt. | 1920 | 16558899 | |
| studies on bacillus botulinus. | 1921 | 19972528 | |
| clostridium putrificum (b. putrificus bienstock), a distinct species. | 1922 | 16558972 | |
| clostridium botulinum: iv. resistance of spores to moist heat. | 1923 | 16558998 | |
| the effect of certain bacteria upon the toxin production of bacillus botulinus in vitro. | 1923 | 16559004 | |
| clostridium putrificum: ii. morphological, cultural and biochemical study. | 1923 | 16559007 | |
| the identification of bacillus botulinus and its toxin in culture and in canned foodstuffs by serological methods. | 1923 | 18010938 | |
| the influence of calcium chloride upon experimental botulism. | 1. calcium chloride given subcutaneously, intraperitoneally, or intravenously has been found to have no effect upon the production of botulism following the injection of bacillus botulinus (strain 80b) into the peritoneal cavity of guinea pigs. 2. treatment of bacillus botulinus with alcohol has been found markedly to decrease its toxicity for guinea pigs. this is in conformity with the work of bronfenbrenner and schlesinger. 3. toxin-free spores of bacillus botulinus have been found pathogenic ... | 1923 | 19868746 |
| botulism. studies on the manner in which the toxin of clostridium botulinum acts upon the body : i. the effect upon the autonomic nervous system. | a survey of the results of these experiments shows, we believe conclusively, that in botulinus intoxication in cats, dogs, and rabbits there is a specific effect upon the portions of the autonomic nervous system which gaskell (14) described as the bulbosacral and prosomatic outflows of connector fibers respectively, which results in a blocking of the nerve impulses of these nerves. the experimental as well as the clinical evidence indicates that there is no damage to the nerves of the thoracicol ... | 1923 | 19868755 |
| botulism. studies on the manner in which the toxin of clostridium botulinum acts upon the body : ii. the effect upon the voluntary nervous system. | 1. in addition to the effect upon the fibers of the parasympathetic nervous system which was described in a previous report (1), the toxin of clostridium botilinum. types a and b, exerts an influence upon the endings of the motor fibers of the voluntary nervous system which leads to a marked susceptibility to fatigue. it has not been determined whether the damage is in the anatomical nerve endings of the somatic motor nerve fibers or upon the myoneural junction, but it is not of the nature of an ... | 1923 | 19868794 |
| cause of immediate death by large doses of botulinus toxin. | parenteral introduction of amounts of the culture filtrate of bacillus botulinus greatly in excess of the minimum lethal dose has been observed to cause the practically immediate death of mice. this result is due to the presence in the filtrates of a chemical poison possessing properties distinct from those of the contained botulinus toxin which itself acts only after a well defined period of incubation. this chemical poison is not neutralized by botulinus antitoxin; it is effective only when la ... | 1924 | 19868905 |
| the detection of bacillus botulinus and bacillus tetani in soil samples by the constricted tube method. | 1924 | 16559040 | |
| clostridium putrificum: iii. a comparison of strains obtained from collections in this country and abroad. | 1924 | 16559052 | |
| the distribution of bacillus botulinus in scottish soils. | 1928 | 20474983 | |
| botulism and its ophthalmic lesions as determined by research with the toxin of clostridium botulinum. | 1929 | 16692840 | |
| the identity of bacillus putrificus bienstock. | 1932 | 16559575 | |
| a taxonomic study of "clostridium putrificum" and its establishment as a definite entity-clostridium lentoputrescens, nov. spec. | 1934 | 16559715 | |
| clostridium botulinum type c in relation to duck sickness in the province of alberta. | 1936 | 16559932 | |
| the utilization of amino acids and of glucose by clostridium botulinum. | 1940 | 16560308 | |
| the occurrence of toxigenic anaerobes, especially clostridium botulinum, in some english soils. | 1942 | 20475633 | |
| some ecological relations of pseudomonas aeruginosa to clostridium botulinum type c. | 1943 | 16560665 | |
| the occurrence of bacillus botulinus, types a and b, in accidental wounds. | 1945 | 16560990 | |
| the occurrence of bacillus botulinus, types a and b, in accidental wounds. | 1945 | 20989338 | |
| the purification of toxin from clostridium botulinum type a. | 1946 | 20989469 | |
| prevalence of clostridium botulinum in soils of central new york state. | 1946 | 20989616 | |
| the purification and crystallization of clostridium botulinum type a toxin. | 1946 | 21026141 | |
| nutritional studies with clostridium botulinum, toxin types a and b. | 1946 | 21064682 | |
| the purification and crystallization of clostridium botulinum type a toxin. | 1946 | 17808402 | |
| effect of flavonols on clostridium botulinum. | 1947 | 17741557 | |
| practical media and control measures for producing highly toxic cultures of clostridium botulinum, type a. | 1947 | 16561264 | |
| effects of toxins of clostridium botulinum and clostridium tetani on acetylcholine synthesis. | 1947 | 20343791 | |
| the elemental and amino acid composition of crystalline clostridium botulinum type a toxin. | 1947 | 20251447 | |
| clostridium botulinum type a toxoids. | 1947 | 20264579 | |
| clostridium botulinum type b toxoids. | 1947 | 20264580 | |
| a preliminary study of the antigenic activity of mixtures of clostridium botulinum toxoid types a and b. | 1947 | 20264581 | |
| the isolation of clostridium botulinum type a from victorian soils. | 1947 | 20267540 | |
| practical media and control measures for producing highly toxic cultures of clostridium botulinum, type a. | 1947 | 20284968 | |
| on the mechanism of paralysis resulting from toxin of clostridium botulinum; the action of the toxin on acetylcholine synthesis and on striated muscle. | 1947 | 20295512 | |
| physiocochemical properties of crystalline clostridium botulinum type a toxin. | 1948 | 18886177 | |
| physiological studies on spore germination, with special reference to clostridium botulinum; carbon dioxide and germination, with a note on carbon dioxide and aerobic spores. | 1948 | 18902255 | |
| physiological studies on spore germination, with special reference to clostridium botulinum; inhibition of germination by unsaturated c18 fatty acids. | 1948 | 18909075 | |
| physiological studies on spore germination with special reference to clostridium botulinum; development of a quantitative method. | 1948 | 18917662 | |
| physiological studies on spore germination with special reference to clostridium botulinum; quantitative aspects of the germination process. | 1948 | 18917663 | |
| physiological studies on spore germination with special reference to clostridium botulinum: i. development of a quantitative method. | 1948 | 16561435 | |
| physiological studies on spore germination with special reference to clostridium botulinum: ii. quantitative aspects of the germination process. | 1948 | 16561436 | |
| physiological studies on spore germination, with special reference to clostridium botulinum: iii. carbon dioxide and germination, with a note on carbon dioxide and aerobic spores. | 1948 | 16561463 | |
| physiological studies on spore germination, with special reference to clostridium botulinum: iv. inhibition of germination by unsaturated c(18) fatty acids. | 1948 | 16561482 | |
| physiological studies on spore formation in clostridium botulinum. | 1948 | 18101744 | |
| hemagglutination by botulinal toxin. | 1948 | 18102220 | |
| [research on botulinum i toxin, anatoxin and antitoxin]. | 1950 | 14771601 | |
| high toxicity of pure botulinum type d toxin. | 1950 | 14780226 | |
| spores of clostridium botulinum in georgia soil. | 1950 | 14793622 | |
| [agglutination of clostridium botulinum, clostridium putrificum and clostridium sporogenes by normal human serum and that of certain animals]. | 1950 | 14852546 | |
| [research on the hemolysin of clostridium botulinum d]. | 1950 | 15425976 | |
| studies on factors affecting the heat resistance of spores of clostridium botulinum. | 1951 | 14861162 | |
| [existence in france of human botulism due to fish and to clostridium botulinum e]. | 1951 | 14869880 | |
| [metabolism of b. botulinus]. | 1951 | 14806120 | |
| a further survey of the action of clostridium botulinum toxin upon different types of autonomic nerve fibre. | 1951 | 14825230 | |
| botulism, a complication of clostridium botulinum wound infection. | 1951 | 14829135 | |
| the behavior of the bolulinus toxins in the ultracentrifuge. | 1951 | 14830257 | |
| clostridium botulinum in a fatal wound infection. | 1951 | 14832034 | |
| [behaviour of toxins of clostridium botulinum and salmonella enteritidis towards antibiotics, chemotherapeutics and dyes]. | 1951 | 14837307 | |
| [contribution to the study of bacterial hemolysins; properties of c and d types of botulinus toxins]. | 1951 | 14839916 | |
| observations on the type a toxin of clostridium botulinum. | 1951 | 14843148 | |
| the lack of identity between hemagglutinin and the toxin of type a botulinal organism. | 1951 | 14850434 | |
| factors affecting the botulinal hemagglutination reaction, and the relationship between hemagglutinating activity and toxicity of toxin preparations. | 1951 | 14885154 | |
| a rapid plate method of counting spores of clostridium botulinum. | 1951 | 14897814 | |
| the pathogenicity of the spores of clostridium botulinum. | 1951 | 20475837 | |
| studies of toxin of clostridium botulinum type d. | 1952 | 14946388 | |
| [botulin toxin type a]. | 1952 | 14947518 | |
| effect of subtilin on spores of clostridium botulinum. | 1952 | 14955507 | |
| subtilin and the spores of clostridium botulinum. | 1952 | 24541795 | |
| [type a botulin toxin; detoxification of toxins and their antigenic properties]. | 1952 | 13012824 | |
| [examination of the possibility of active immunization of experimental animals with oral clostridium botulinum toxin]. | 1952 | 13014717 | |
| [technique of extraction of the toxin of cl. botulinum (c) from bacterial bodies]. | 1952 | 13048125 | |
| [study of catgut injections by clostridium botulinum a]. | 1952 | 12976796 | |
| description of clostridium botulinum type d recovered from soil in south australia. | 1952 | 12997450 | |
| [studies on botulinus toxin a]. | 1952 | 13001994 | |
| characterization of botulinal hemagglutination. | 1953 | 13007684 | |
| motor nerve filament block produced by botulinum toxin. | 1953 | 13048675 | |
| studies on mink food experimentally inoculated with toxin-free spores of clostridium botulinum types a,b,c, and e. | 1953 | 13065666 | |
| the temperature relations of clostridium botulinum, types a and b. | 1953 | 13066383 | |
| the results of direct injections of botulinum toxin into the central nervous system of rabbits. | 1953 | 13070232 | |
| [experimental studies on development of antitoxins in animals immunized with botulin anatoxin type a]. | 1953 | 13071648 | |
| botulinum type a toxin: properties of a toxic dissociation product. | 1953 | 13081146 | |
| in vitro effects of botulinum toxin (type d). | 1953 | 13109821 | |
| botulinum toxin and the motor end plate. | 1953 | 13120965 | |
| the effects of bacterial toxins on the nervous system. | 1953 | 13134660 | |
| [studies on antigenic community among five botulin toxins]. | 1953 | 13148706 | |
| [resistance of botulins diluted in water]. | 1953 | 13148707 | |
| [effect of purifying agents on botulins diluted in water]. | 1953 | 13148708 | |
| [new investigations on botulinism and its five toxic types]. | 1953 | 13148799 | |
| effect of some antibiotics on clostridium botulinum. | 1953 | 24542418 | |
| the action of botulinum toxin on motor-nerve filaments. | 1954 | 13152695 | |
| hemagglutination by clostridium botulinum type d. | 1954 | 13156619 |