Publications

[study of soluble antigens of type e clostridium botulinum by gel diffusion].		1965	4956463
intracerebral perfusion in awake monkeys.		1966	4959059
the influence of cellular immunity factors on oncogenesis in infection with polyoma virus in the syrian hamster. preliminary report.		1966	4289311
[effect of epiphysectomy on the ovary of the golden hamster (mesocricetus auratus waterh.)].		1967	4231631
sensitization of escherichia coli to actinomycin d by the arrest of protein synthesis.		1968	4882031
immunization of day-old chicks against fowl pox.		1968	4303939
an unusual inhibitory effect of histamine: suppression of atropine-resistant tetanic spasms after mepyramine block of histamine contractions.		1969	4390876
[functional relationship between lnpf (vascular permeability factor of ganglia) and histones].		1969	4981852
folate derivatives in healthy and rust-infected primary leaves of wheat.		1969	4983293
non-specific and adaptive immunity in renal transplantation.		1969	4944227
effect of adenosine and deoxyadenosine on the incorporation and breakdown of thymidine in escherichia coli k-12.	deoxyadenosine (adr) and adenosine (ar) enhance the incorporation of thymidine (tdr) into bacterial deoxyribonucleic acid (dna) by the inhibition of tdr phosphorolysis in vivo. neither of the purine nucleosides has an effect on the reaction catalyzed by tdr phosphorylase in vitro. adr induces tdr phosphorylase and both purine nucleosides induce purine nucleoside phosphorylase. ar can stimulate uptake of more tdr into bacterial dna than adr.	1970	4914568
existence of the colicinogenic factor-sex factor coli-b-p9 as a supercoiled circular dna-protein relaxation complex.		1970	4918011
[direct conversion of dehydroepiandrosterone sulfate by rat erythrocytes in vitro].		1971	4258425
endogenous metabolism of staphylococcus aureus.		1972	5017753
[gamma glutamyl carboxypeptidase from chicken pancreas].		1972	5073874
the effect of energy supplied from the diet and from environment heat on the response of chicks to different levels of dietary lysine.		1972	4643136
[on the distribution of human serum protein levels in pulmonary tuberculosis and a new parameter indicating the severity of the disease].		1972	4676930
[serologic sutdy of rodent fleas for plague].		1973	4780105
regional cerebral blood flow and regional metabolism in cold induced oedema.		1973	4780645
on the pharmacokinetics of the ethanol metabolite acetate: elimination from the blood and cerebrospinal fluid.		1973	4800451
effect of actinomyces viscosus on the establishment and symbiosis of streptococcus mutans and streptococcus sanguis in spf rats on different sucrose diets.		1975	123171
contrast and electrolyte dynamics of the intravenous pyelogram. ii. disparities in serum and urine concentrations of meglumine and anion.	intravenous or intra-aortic injections of meglumine iothalamate in dogs indicate a slightly different tissue distribution and excretory pattern of the meglumine cation and the iothalamate anion. differences in serum and urinary concentrations of these ions suggest some cellular penetration of the meglumine anion. in addition, there seems to be some evidence for both tubular absorption and tubular excretion of meglumine as a minor component in the renal excretion of this ion. no significant diffe ...	1975	1184320
studies on the composition of pig serum lipoproteins. isolation and characterization of different apoproteins.	1. different lipoprotein density fractions from pig serum were isolated by phosphotungstate precipitation followed by purification in the preparative ultra-centrifuge. 2. the protein part of very low density lipoproteins was composed of approximately 52 percent lipoprotein b apoprotein and the rest of lipoprotein c ii apoprotein and other as yet unidentified peptides. 3. the protein moiety of low density lipoproteins consisted primarily of lipoprotein b apoprotein (over 95 percent); the amino ac ...	1975	166686
characterization of sv40 dna rescued from transformed mouse cells.		1975	169101
endogenous prostaglandin release contributes directly to coronary artery tone.	an in vitro coronary artery preparation of beef heart was found to synthesize and release continuously large amounts of a prostaglandin of the e type. inhibition of prostaglandin synthesis with aspirin, indomethacin, or eicosa-5,8,11,14-tetraynoic acid induced a sustained contraction of the coronary artery, and pretreatment with indomethacin diminished markedly the output of prostaglandin into the bathing medium. it appears that prostaglandin e1, generated from within the vessel wall itself, may ...	1975	1175084
[primary structure of cytoplasmic aspartate aminotransferase from pig heart muscle. isolation, purification and characterization of thermolytic peptides].		1975	1203378
[hypothetical concept: the physiopathological entity of monoaminergic psychoses].	the importance of amino acid transport across the blood-brain barrier as the limiting factor in the metabolism of monoamines has been emphasized by many recent publications. particularly critical is the transport of tryptophan, since tryptophan hydroxylase is not saturated. this transport is regulated by complex mechanisms, both at the periphery (total and free plasmatic levels and levels of the other essential amino acids) and centraly (by feedback mechanism initiated at the pre- and post-synap ...	1975	1082812
a circular dna-protein complex adenoviruses and its possible role in dna replication.		1975	169089
the role of the pituitary in acne.		1976	138539
effects of poly(1-vinyluracil) and poly(9-vinyladenine) on viral rna-directed dna polymerase.	the effects of poly(1-vinyluracil) [poly(vu)] and poly(9-vinyladenine) [poly(va)] on the rna-dependent dna polymerase activity of murine leukemia virus (moloney strain) were studied. vinyl polymers themselves cannot act as templates for the polymerase. however, if a vinyl polymer is added to a polymerase reaction mixture in which a complementary polynucleotide serves as the template, the reaction is inhibited: thus with polyribocytidylic acid as template and oligodeoxyguanylic acid as primer, ne ...	1976	56995
in vitro translation of encephalomyocarditis viral rna: synthesis of capsid precursor-like polypeptides.		1976	178097
electron microscopical and enzyme histochemical changes in the rat myocardium during prolonged autolysis.	the effect on rat myocardium of autolysis at 19 degrees c, for up to 20 days, was studied by electron microscopy and enzyme histochemistry. the enzymes studied included monoamine oxidase (mao), sytochrome oxidase (cyto), non-specific esterase ((ns.e.), phosphorylase (p-ase), succinate dehydrogenase (sdh) and various nad- and nadp-linked dehydrogenases. the myocardium lost its histochemical p-ase activity within a few hours of autolysis, whereas the activity of all other enzymes remained quite no ...	1976	179522
the storage lipids in tangier disease. a physical chemical study.	the physical states and phase behavior of the lipids of the spleen, liver, and splenic artery from a 38-yr-old man with tangier disease were studied. many intracellular lipid droplets in the smectic liquid crystalline state were identified by polarizing microscopy in macrophages in both the spleen and liver, but not in the splenic artery. the droplets within individual cells melted sharply over a narrow temperature range, indicating a uniform lipid composition of the droplets of each cell. howev ...	1977	193870
pregastric esterase and other oral lipases--a review.	the secretion of pregastric esterase and other oral lipases has been detected in 13 species. research on secretion by the human, calf, kid goat, lamb, and rat of pregastric esterase has been significant. secretion by calves is little affected by age or diet but is greater when calves are nipple fed than when pail fed. whole milk sham-fed to calves exhibits immediate, sharp decreases in ph and rennet coagulation time resulting from liberation of free fatty acids by pregastric esterase. bacterial ...	1977	321489
immune responses during human schistosomiasis mansoni. i. in vitro lymphocyte blastogenic responses to heterogeneous antigenic preparations from schistosome eggs, worms and cercariae.	in vitro lymphocyte blastogenesis assays were performed using peripheral blood lymphocytes obtained from patients with schistosomiasis mansoni. their infection was well characterized both clinically and in regard to the duration and intensity of schistosoma mansoni infection. subjects who were either not infected with any helminths or who were negative for s. mansoni but infected with other helminths provided two control groups. cultures were exposed to various concentrations of heterogeneous so ...	1977	300716
particle-bound enzymes in the bloodstream form of trypanosoma brucei.	we have screened the bloodstream form of trypanosoma brucei for the presence of enzymes that could serve as markers for the microbodies and the highly repressed mitochondrion of this organism. none of seven known microbody enzymes were detected at all, but glycerol-3-phosphate oxidase, atpase, isocitrate dehydrogenase, acid phosphatase and part of the hyperoxide dismutase and malate dehydrogenase activities were found to be particle-bound after fractionation of homogenates by differential centri ...	1977	195809
interactions of gonadotropins with corpus luteum membranes. i. properties and distributions of some marker enzyme activities after subcellular fractionation of the superovulated rat ovary.	the properties of a number of enzyme activities of the superovulated rat ovary have been studied to establish optimal assay conditions and specific assay procedures for each activity. the activities were chosen on the basis of their extensive use in other tissues of the rat as marker enzymes for the major cell organelles. homogenates of superovulated rat ovaries were subjected to fractionation by differential rate centrifugation, and sedimentation profiles were constructed for each marker enzyme ...	1978	217656
isolation and partial characterization of rat cns axolemma enriched fractions.	axolemma-enriched fractions were prepared from rat brain by osmotic shock of a purified preparation of myelinated axons and subsequent separation of myelin, two axolemma-enriched fractions and myelin-free axons by density gradient centrifugation. compared with the starting whole homogenate, the fractions were enriched in specific activity of na+k+ atpase, acetylcholinesterase, 5'nucleotidase as well as 2',3'-cyclic nucleotide 3'phosphohydrolase. compared with myelin, the axolemmal fractions are ...	1978	206316
production and chemical studies of protease from bacillus subtilis (sh-6) egyptian strain.	bacillus subtilis (sh-6) egyptian strain, isolated from hides, gave the highest protease activity. luxurious growth and protease production were obtained by the use of a medium containing 8% of potato starch, 0,1 m of ammonium phosphate as carbon and nitrogen sources. results indicate that borate buffer exerted a deleterious effect on the protease production. comparing citrate and phosphate buffers, it was found that citrate gave lower protease activity than phosphate. there is a positive respon ...	1978	98932
effect of human immunoglobulin preparations on fc rosette formation between anti-d-coated erythrocytes and lymphocytes.	human immunoglobulin (ig) preparations were tested for their inhibitory effect on fc rosette formation between anti-d-coated human erythrocytes and lymphocytes, as compared to their complement activating capacity. both of the two biological activities ascribed to the sites in the fc portion of the igg molecules were found to be reduced in the pepsin-treated, as well as in the s-sulfonated ig preparations, as compared to the activities of the normal human ig preparation. in the plasmin-treated ig ...	1978	150144
eosinophil chemotactic factor (ecf). iii. generation in human peripheral leukocytes.	eosinophil chemotactic factor (ecf) can be released from human peripheral leukocytes by an ige-anti-ige reaction, by the calcium ionophore a 23187 and during phagocytosis. supernatants and sonicates of unstimulated cells contain little or no ecf. on stimulation, however, ecf activity increases in the cells and even more so in the supernatants. this holds for purified neutrophils (pmns) as well as for basophil-containing mononuclear cell preparations. these findings contrast with those in lung ho ...	1978	344230
effects of ascorbate loading on pmn bacterial iodination and other functions.		1978	211233
skin papillomas in an impala (aepyceros melampus) and a giraffe (giraffa camelopardalis).	viral particles, typical of the papovavirus family, were demonstrated by electronmicroscopy in small papillomas found on the feet of an impala (aepyceros melampus) and on the face of a giraffe (giraffa camelopardalis) in kenya. histologically the tissues proved to be typical papillomas. the viral particles measured 38 nm and 40 nm in diameter in all tissue sections from the impala and giraffe respectively.	1978	211271
comparison of interferon action in interferon resistant and sensitive l1210 cells.	translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ...	1978	212514
mucin-producing atypical bronchial carcinoid.	in a case of atypical mucin-producing bronchial carcinoid in a 40-year-old man covert metastases were present at the time of lobectomy and were revealed at necropsy--a feature highlighting the malignant potential of the atypical carcinoid.	1978	219040
congeners of dom: effect of distribution of the evaluation of pharmacologic data.		1978	101880
mutagenicity of diallate, sulfallate, and triallate and relationship between structure and mutagenic effects of carbamates used widely in agriculture.	in an investigation of the mutagenic properties of 20 carbamate herbicides and fungicides by use of the salmonella/microsome mutagenicity test as developed by ames et al. (mutation res., 31: 347-364, 1975), we have found that three thiocarbamate compounds, diallate, sulfallate and triallate, are mutagenic in the presence of a liver microsomal fraction on strains ta1535 and ta100. this indicates that the metabolic products of these thiocarbamates are causing base-pair substitutions. since the 2-c ...	1978	201368
mineralization of the enamel of ovine permanent central incisor teeth using microhardness and histological techniques.		1979	116728
comparison of antigen-specific i-region-associated cell interaction factors.	two basic types of factors reacting with anti-i region (anti-ia) antisera are compared, those derived from macrophage-like antigen presenting cells and others derived from t-lymphocytes, of either the suppressor or helper type. despite the common property of reacting with anti-ia antisera, the two sets of factors differ by many criteria. macrophages, upon culture with antigen, release complexes of ia antigen and a fragment of the original immunogen. this material is only produced by responder ma ...	1979	93870
evaluation of pseudorabies viral antigens in the agar gel immunodiffusion test.	procedures designed to extract pseudorabies viral (prv) antigens from prv-infected tissue cultures were investigated to determine whether differences in extraction method had an effect upon the final concentrated antigenic product. all four of the preparations made from prv-infected tissue culture cells (trypsin extract and disrupted cells) or entire prv-infected cultures (polysorbate 80 extract and (nh4)2so4 precipitate) contained relatively large amounts of the same antigen, whereas cell-free ...	1979	92905
potency of 10 bcg vaccines as evaluated by their influence on the bacillemic phase of experimental airborne tuberculosis in guinea-pigs.		1979	387796
the cachexia of cancer.	this review examines the contributions made by anorexia, loss of taste, malabsorption and disturbances of intermediary metabolism to the cachexia of cancer. methods of nutritional assessment are outlined and mention is made of the usefulness of nutritional support as an adjunct to anti-cancer therapies.	1979	393313
[the molecular biology of aging -- 15: structure and function of the genetic apparatus in aging. ii. synthesis and metabolism of rna].	with aging in different organs there are similar or tissue specific changes of the ribonucleic acids in respect of the quantity, the spectrum of different rna species and the metabolism of rna. among these processes the template function of the chromatin and the behaviour of the rna polymerases are important influencing factors. in aging the sensitivity of the rna synthesis against hormonal stimulation is decreased in the most cases. a survey about the results of many in vivo and in vitro experi ...	1979	395770
activation of tumoricidal properties in mouse macrophages by lymphokines encapsulated in liposomes.	cell-free culture supernatants rich in macrophage-activating factor (maf) activity obtained from mitogen-stimulated f344 rat lymphocytes have been encapsulated within liposomes of differing size and lipid composition and their ability to render normal mouse macrophages cytotoxic for tumor cells in vitro has been compared with that of unencapsulated (free) maf added to the extracellular medium. normal macrophages from c57bl/6, c3h/hen, and c57bl/6 x c3h f1 mice treated with liposome-encapsulated ...	1979	427777
neurectoderm markers retained in phenotypical skeletal muscle cells arising from a glial cell line.		1979	492321
[toxicologic-hygienic characteristics of the preparation nerosin, an agent for protecting plants and soils subject to wind erosion].	a year's experiment on albino rats fed with bread prepared from spring wheat "saratovskaya-29" grown with the utilization of the antideflationary agent nerosin (1.5 t/hectare) showed that this bread did not effect the functional condition of the liver (the antitozic and protein-forming functions), as well as the redox activity of the blood constituents catalase and peroxidase, and the morphological structure of the peripheral blood of the animals. an elevation of glucuronic acid metabolism (33.1 ...	1979	516602
experimental s. mansoni infection in mice. blood white cells, serum proteins, glycemia and blood urea in various stages of the infection.		1979	545638
overview. the major histocompatibility system of the rat.		1979	92081
effect of colicins ia and e1 on ion permeability of liposomes.	colicins ia and e1 are shown to inhibit the formation and bring about the collapse of a potassium diffusion potential imposed across the membrane of liposomes prepared from soybean or escherichia coli phospholipids. such depolarization results from a colicin-induced increase in membrane ion permeability. colicins e2 and e3 do not depolarize such membranes. in addition to the colicin ia-induced rapid efflux of preloaded rubidium, sodium, phosphate, or choline from liposomes, a slower efflux of pr ...	1979	93288
hereditary alpha 2-macroglobulin deficiency.	on screening of a normal material 1 man was found (age 37) who on repeated determinations had a low alpha 2m, namely 25 % with electroimmuno assay according to laurell. investigation of the family revealed that the mother (age 69) and one daughter (age 5) had low values too. all other coagulation and fibrinolytic components were normal. they had no signs of increased fibrinolysis and normal levels of alpha 2-antiplasmin, alpha 1-antitrypsin and antithrombin iii. liver function tests were normal. ...	1979	94459
the role of antigen-specific t cell factors in the immune response.		1979	94504
genetic polymorphism and close linkage of two alpha 1-protease inhibitors in horse serum.	two-dimensional electrophoretic analysis of horse serum proteins was done by a first-dimension separation in agarose gel (ph 5.4) followed by a second-dimension separation in horizontal polyacrylamide gel (ph 9.0). this method resulted in improved and reproducible separation of many alpha-globulins. two groups of alpha 1-globulins, designated pi1 and pi2, were found to be protease inhibitors. preliminary studies indicated that pi1 and pi2 proteins differed from each other in molecular weight and ...	1979	94978
treatment of severe herpes keratitis with cryosurgery and immunotherapy.	the contrasting type of lesion produced in the first eye of non-immune and the second eye of the then immune rabbits using herpes simplex type i virus is demonstrated. cryosurgery may make the first eye worse but the second eye is healed. a large percentage of second eyes heal spontaneously, however, as circulating antibody titres are high. artefacts may be mistaken for lesions in the immune eye but superficial viral growth has a characteristic plaque-like appearance. one hundred eyes with recur ...	1979	95060
antibodies against measles antigen in the laboratory housed rhesus and bonnet monkeys.		1979	107117
[hypothalamic hypophysiotropic hormones: biochemical and clinical aspects. i. thyroliberin and luliberin].		1979	117441
a microtechnique for the rapid analysis of macromolecule synthesis in minicultures of mammalian cells.	a new micromethod, called the stanzen technique, is described for the rapid determination of dna and protein content as well as the incorporation rates of radioactively labeled precursors into macromolecules in cells growing in replica minicultures on plastic petri dishes. the procedure yielded reproducible results assaying only minimal cell numbers per sample and was applied for studying both primary or early passaged cell cultures (mouse epidermal cells and fibroblasts) and a malignantly trans ...	1979	478561
[cyclic 3',5'-amp metabolism in progressive muscular dystrophy patients].	concentration of cyclic amp was distinctly decreased in muscular tissue of patients with dushenn's myodystrophy. simultaneously, in patients with the myopathy basal activity of adenylate cyclase as well as activation of the enzyme by adrenaline and sodium fluoride were decreased. as a compensation, activity of phosphodiesterase was also decreased. content of camp, activity and activation of adenylate cyclase were similar to normal state in patients with erb's and landuzi--dejerin's myopathies; a ...	1981	216142
acupuncture in narcotic withdrawal: a preliminary report on biochemical changes in the blood and urine of heroin addicts.	eight female heroin-addicted subjects were treated over a 10-day period by acupuncture and electrical stimulation (aes). their plasma acth, cortisol and c-amp levels were reduced after initial aes treatment. the reduction of c-amp was significant the most of the three. the suppression of these compounds may be associated with the temporary relief of withdrawl symptoms on and after each aes treatment in the first three days. on the third day, acth, cortisol and c-amp levels did not show significa ...	1982	216444
survival of smallpox virus.		1985	2857360
double osteotomy operation in the surgical treatment of coxa plana disease.	during the years 1975 to 1982, what was named the double osteotomy--which is a combination of pelvic osteotomy together with subtrochanteric varus, extension and derotation osteotomy--was applied to 26 cases suffering from coxa plana (perthes-calvé-legg disease). the postoperative follow up averages a period of three years and five months and was undertaken at the department of orthopedics and traumatology of the faculty of medicine, university of ankara, turkey.	1985	3832036
autonomic regulation of the pulmonary circulation.	responses to vagal stimulation, acetylcholine, catecholamines, and sympathetic nerve stimulation were investigated in the feline pulmonary vascular bed under conditions of controlled pulmonary blood flow and constant left atrial pressure. results of these studies suggest that, in the cat, the vagus is composed of efferent fibers from both the sympathetic and parasympathetic systems. the data also suggest that the feline pulmonary vascular bed is functionally innervated by cholinergic nerves, and ...	1985	2409403
the effect of therapeutic soft contact lenses on antibiotic delivery to the cornea.	the effects of high (71%) and low (38.6%) water content lenses on antibiotic delivery to the cornea were studied in rabbits by measuring corneal tobramycin concentrations 1, 2, 4 and 6 hours after topical application at intervals of 15 minutes. in the presence of the low water content lens corneal drug levels were higher than in control corneas for every time point assayed. this difference was only significant at 4 hours (p less than 0.05). in eyes wearing the high water content contact lens cor ...	1985	3975000
secretion of anti-müllerian hormone by immature bovine sertoli cells in primary culture, studied by a competition-type radioimmunoassay: lack of modulation by either fsh or testosterone.	secretion of anti-müllerian hormone (amh) by immature bovine sertoli cells in primary culture was studied through a competition-type ria employing a polyclonal antibody and 125i-labelled purified amh. this ria is approximately 10 times more sensitive than the solid-phase two-site monoclonal antibody-based ria described previously. biosynthesis and secretion of amh by cultured sertoli cells require approximately 48 h, are not influenced by fsh or testosterone and steadily decrease over a one-week ...	1985	3000849
gastrin release from dispersed gastrinoma cells: effects of calcium and calcium ionophore (a23187).	dispersed single-cell suspensions of human gastrinoma tissue were incubated for 15, 60, and 120 min in a calcium-containing medium, (0.1, 2, 10 mm) in calcium-free medium and in calcium-free medium containing the calcium ionophore a23187 (0.01, 1, and 100 micrograms/ml). supernatant and pellet (intracellular) gastrin levels were determined by radioimmunoassay. supernatant gastrin levels remained stable over 120 min in calcium chloride or calcium gluconate containing medium, while intracellular p ...	1985	3930881
increased interleukin-1 production and monocyte suppressor cell activity associated with human tuberculosis.	interleukin-1 (il-1) production by blood monocytes and blastogenesis produced by tuberculin purified protein derivative (ppd) in blood t lymphocytes were examined in patients with pulmonary tuberculosis. monocytes were isolated from blood mononuclear cells by plastic adherence, and il-1 activity was determined in the mouse thymocyte proliferation assay. monocytes from patients with tuberculosis produced significantly higher activities of il-1 than did those from healthy tuberculin reactors when ...	1986	2935057
effect of 1% sodium hyaluronate (healon) on a nonregenerating (feline) corneal endothelium.	a series of experiments were performed to investigate the effect of 1% sodium hyaluronate (healon) on the nonregenerating corneal endothelium of the cat. aqueous humor replacement with 1% sodium hyaluronate resulted in mild, transient elevations of intraocular pressure compared to eyes that were injected with balanced salt solution. sodium hyaluronate 1% protected the feline endothelium against cell loss incurred by contact with hyaluronate-coated intraocular lenses compared to endothelial conta ...	1986	3531081
effect of 1% sodium hyaluronate (healon) on a nonregenerating (feline) corneal endothelium.	a series of experiments were performed to investigate the effect of 1% sodium hyaluronate (healon) on the nonregenerating corneal endothelium of the cat. aqueous humor replacement with 1% sodium hyaluronate resulted in mild, transient elevations of intraocular pressure compared to eyes that were injected with balanced salt solution. sodium hyaluronate 1% protected the feline endothelium against cell loss incurred by contact with hyaluronate-coated intraocular lenses compared to endothelial conta ...	1986	3531081
rapid regeneration in postischaemic skeletal muscle with undisturbed microcirculation.	the regeneration of skeletal muscle cells was investigated in the extensor digitorum longus muscle (edl) of rats subjected to hindlimb tourniquet ischaemia preceded by glycogen depletion. in this experimental model a distinct population of 'white' muscle cells are preferentially damaged, while there is minor damage to microvessels. a rapid regenerative response occurred after injury. mitotic figures were obvious in satellite cells of damaged as well as of uninjured muscle cells within 48 h after ...	1986	3788618
[electron microscopic studies of the islands of langerhans in the rat. the b cell and the capillaries].		1986	3543383
antibodies to distal carboxyl terminal epitopes in the v-fms-coded glycoprotein do not cross-react with the c-fms gene product.	the product of the v-fms oncogene is an integral transmembrane glycoprotein that is closely related to the cell surface receptor for the macrophage colony stimulating factor, csf-1. a fragment of the v-fms gene encoding a major portion of the extracellular amino terminal domain, the membrane-spanning segment, and the entire carboxyl terminal tyrosine kinase domain of the glycoprotein was molecularly cloned into an inducible prokaryotic expression plasmid. polypeptide products consisting only of ...	1986	2425481
in vitro fluid dynamic characteristics of aortic bioprostheses: old versus new.	the in vitro fluid dynamic characteristics of a variety of old- and new-generation porcine and pericardial aortic bioprostheses were investigated under pulsatile flow conditions. the pressure drop results indicate that the old valve designs have performance indices in the range of 0.30 to 0.42, while the new, low-pressure fixed designs have performance indices of 0.50 to 0.70. leaflet photography indicated that the new designs also have superior opening and closing characteristics. flow visualiz ...	1986	2937982
endocytosis of proteoheparan sulfate by cultured skin fibroblasts.	endocytosis by cultured human skin fibroblasts of 35so4(2-)-labeled proteoheparan sulfate from fibroblast secretions was quantitatively investigated. at a constant dose of proteoheparan sulfate, uptake and subsequent intracellular degradation but not binding to the cell membrane increased with time. compared with the endocytosis of total secreted proteoglycans containing predominantly a small proteodermatan sulfate, uptake of proteoheparan sulfate was 5- to 20-fold lower. nevertheless, uptake of ...	1986	2943303
the epidemiology of the acquired immunodeficiency syndrome.		1986	3008169
absence of a unique relationship between active transport of lactose and protonmotive force in e. coli.	the relationship between active transport of lactose via the lactose permease and the protonmotive force has been determined in e. coli cells using either the respiratory chain inhibitor cyanide or protonophores to decrease the protonmotive force progressively. in contradiction with the prediction of the delocalized chemiosmotic theory, two different relationships were obtained depending on the method used.	1986	3025020
comparison of human growth hormone levels in children with satisfactory and unsatisfactory growth.	sixty-six children with satisfactory growth and 73 with unsatisfactory growth (both sexes) from three different age groups (1 year, 5 years and 10 years) were included in this study. it was observed that the serum concentrations of human growth hormone (hgh) in children with satisfactory growth ranged from 1.00 to 4.00 ng/ml and never exceeded 4.00 ng/ml. in a comparative study there was a significant increase in serum hgh levels in subjects of all age groups who were not growing satisfactorily. ...	1987	2956220
human milk-derived lactoferrin inhibits mitogen and alloantigen induced human lymphocyte proliferation.	purified lactoferrin (lf), isolated from human milk, was tested for its effect on human t-lymphocyte proliferative responses to phytohemagglutinin (pha) and to alloantigens in mixed lymphocyte culture. lf inhibited proliferation in both assays in a dose-dependent manner. the suppressive effect was not due to lf mediated cytotoxicity since washing cells that had been pre-incubated with lf restored their proliferative activity. lf was most effective in suppressing the pha response when added withi ...	1987	2963123
the effect of thiamin supplementation on the thiamin status of turkey poults with ethanol-induced cardiomegaly.	1. turkey poults were treated with graded doses (0-5% v/v) of ethanol for 6 weeks. some birds were concomitantly injected intramuscularly with thiamin. 2. erythrocyte transketolase (tk) activity was significantly decreased and the erythrocyte pyrophosphate (tpp) effect and blood concentrations of lactate and pyruvate were statistically greater in all ethanol-treated poults by 42 days. 3. thiamin restored tk activity to normal levels and decreased the tpp effect and blood concentrations of lactat ...	1987	2820834
capnocytophaga bacteremia complicating premature delivery by cesarean section.	a case of endomyometritis associated with capnocytophaga ochracea bacteremia following premature delivery is described. the patient, a 30 year old woman without immunological incompetence or other predisposing disease, responded to peroral pivmecillinam. capnocytophaga spp. should be considered a possible cause of post-partum endometritis.	1987	3436319
anti-candida drugs--the biochemical basis for their activity.	the past years have seen a continuous effort toward the synthesis of new antifungal agents. most of them belong to the n-substituted imidazoles and triazoles. another interesting series of antifungals are the allylamines. biochemically, both the azole derivatives and the allylamines belong to the class of ergosterol biosynthesis inhibitors and thus differ from the polyene macrolide antibiotics. indeed, it is now believed that the antifungal action of the polyenes, nystatin and amphotericin b, is ...	1987	3319421
survey of experimental data on fetal liver transplantation.	fetal liver transplantation has been shown to induce hematological and immunological reconstitution in irradiated rodents, dogs, horses, and sheep. engraftment and reconstitution without gvhd has been readily obtained using histocompatible donors. when mismatched fetal donors were used, a comparatively larger number of donor cells was required, in addition to pre-treatment of host with higher doses of irradiation or irradiation plus chemotherapy. stem cell suspensions devoid of any t lymphocyte ...	1987	2893475
[structural analysis of the functional status of the brain as affected by bemethyl using pattern recognition theory].	evoked visual potentials in associated, parietal and second somatosensory zones of the neocortex were analysed in trained cats using implanted electrodes. the influence of bemethyl on the structure of behavioral reactions was analysed using theoretical methods of perceptual images, particularly the method of cluster analysis. bemethyl was shown to increase the level of interaction between the functional elements of the system, leading to a more stable resolution of problems facing the system, as ...	1987	3676492
penicillin tolerance in streptococcus faecium atcc 9790.	tolerant strains of streptococcus faecium had higher levels of muramidase 2 and lower levels of trypsinactivable muramidase 1 than did susceptible strains. susceptible strains lysed faster than did tolerant strains in buffer and at some antibiotic concentrations. the addition of triton x-100 produced equal lysis rates for susceptible and tolerant cultures.	1987	3662476
retinal ganglion cells projecting to the accessory optic system in the rat.	the present data identify the distribution and morphological features of a homogeneous group of rat retinal ganglion cells. these cells were labelled after injection of either horseradish peroxidase or a fluorescent tracer, fast blue, into the medial terminal nucleus (mtn) of the accessory optic system. after retrograde fluorescent labelling, mtn-projecting retinal ganglion cells were intracellularly injected with lucifer yellow to reveal their complete dendritic morphology. there were on averag ...	1987	3624547
[questions and answers on breast feeding: the quality of human milk].		1987	3644946
[triglyceride fatty acids of abdominal adipose tissue in two lines of chickens rendered lean or fat by selection].	newly-hatched chickens from two lines selected for high or low abdominal fat/live weight ratio, were fed on a stock low-lipid diet (2.9 wt % lipids) for nine weeks. linoleic acid made up 54.3% of dietary fatty acids. their abdominal adipose tissue and liver triglycerides were then isolated for fatty acid analysis. the linoleic acid content of abdominal fat triglycerides was higher in lean than in fat chickens (19.2 vs 16.4% of triglyceride fatty acids, respectively). this difference was highly s ...	1987	3659563
protection against atherogenesis with the polymer drag-reducing agent separan ap-30.	the inhibitory effect of separan ap-30, an anionic polyacrylamide, on atherosclerotic plaque formation in aortas of rabbits on a high (2%) cholesterol diet was tested over a period extending from 37 to 170 days. atherogenesis was quantified morphometrically by application of a computer-assisted image analysis of histologic cross sections of the aorta. the area of vessel wall-atheroma interface, fraction of lumen occluded, and other indexes of atherogenesis were measured in each of 26 segments of ...	1987	3815772
[sensory neuropathy and metronidazole. apropos of a recent case with ultrastructural study].		1987	204035
effects of sucralfate or mild irritants on gastric mucosal damage and prostaglandin e2 production.		1988	3164527
synapses from bipolar cells onto dopaminergic amacrine cells in cat and rabbit retinas.	dopaminergic amacrine cells in the vertebrate retina have long been characterized as 'interamacrine' as they were only found to be pre- and postsynaptic to other amacrine cells. immunohistochemistry with antibodies directed against tyrosine hydroxylase (th) revealed synapses from bipolar cell axon terminals to th-containing neuronal processes at ribbon synapses in the rhesus monkey retina. this finding challenged the notion of the dopaminergic amacrine cell phenotype as 'interamacrine'. in order ...	1988	2906268
[3h]sch 23390 binding to d1 dopamine receptors in the basal ganglia of the cat and primate: delineation of striosomal compartments and pallidal and nigral subdivisions.	the distribution of d1 dopamine receptors was studied autoradiographically in the basal ganglia of the cat, monkey and human. these receptor binding sites were labeled directly with the d1-selective antagonist [3h]sch 23390, and ligand-binding assays were performed concurrently. serial- or same-action analysis permitted comparisons among d1 binding distributions, acetylcholinesterase staining and tyrosine hydroxylase immunoreactivity. in all species studied, the dorsal striatum exhibited patches ...	1988	2901690