Publications

basic studies on 3', 4'-dideoxykanamycin b.		1973	4205657
letter: more about vitamin c.		1974	4431377
metastatic nontraumatic clostridium septicum osteomyelitis.	nontraumatic clostridial infections are rare, but need to be diagnosed and treated early or high morbidity and mortality rates result. we believe that this is the first reported case of metastatic nontraumatic clostridium septicum osteomyelitis. early treatment with surgical debridement and parenteral antibiotics without hyperbaric oxygen was used. an associated occult rectal malignancy was discovered and treated.	1985	3980945
purification and kinetic characterization of a phenol-sulfating form of phenol sulfotransferase from human brain.	the identification of three forms of phenol sulfotransferase (pst) in human brain and the subsequent purification and kinetic characterization of a phenol-sulfating form of the enzyme are described. two forms of pst which were capable of conjugating phenol and a third form which sulfated dopamine were resolved from one another using deae-cellulose chromatography. one of the phenol-sulfating forms (p1-pst) was subsequently purified on affi-gel blue and sephacryl s-200, giving a final purification ...	1986	3463246
proteolytic modification of rat prolactin by subcellular fractions of the lactating rat mammary gland.	the current study explored prolactin proteolysis by rat lactating mammary gland. 125i-labelled rat prolactin was incubated with tissue fractions of lactating mammary gland and the extent of prolactin degradation and fragment formation was visualized and densitometrically quantitated from autoradiographs derived from sds-polyacrylamide gel electrophoresis under reducing conditions. at ph 4.5, the 25 000 x g pellet of mammary gland converted intact prolactin (23 kda band) to proteolytic fragments ...	1986	3754158
sulfite oxidase from chicken liver. the role of imidazole and carboxyl groups for the reaction with cytochrome c.	oxidation of sulfite to sulfate by sulfite oxidase is inhibited when the enzyme is treated with reagents known to modify imidazole and carboxyl groups. modification inhibits the oxidation of sulfite by the physiological electron acceptor cytochrome c, but not by the artificial acceptor ferricyanide. this indicates interference with reaction steps that follow the oxidation of sulfite by the enzyme's molybdenum cofactor. reaction with diethylpyrocarbonate modifies ten histidines per enzyme monomer ...	1986	3019695
sulfite oxidase from chicken liver. the role of imidazole and carboxyl groups for the reaction with cytochrome c.	oxidation of sulfite to sulfate by sulfite oxidase is inhibited when the enzyme is treated with reagents known to modify imidazole and carboxyl groups. modification inhibits the oxidation of sulfite by the physiological electron acceptor cytochrome c, but not by the artificial acceptor ferricyanide. this indicates interference with reaction steps that follow the oxidation of sulfite by the enzyme's molybdenum cofactor. reaction with diethylpyrocarbonate modifies ten histidines per enzyme monomer ...	1986	3019695
iodine in contrast agents and skin disinfectants is the major cause for hypothyroidism in premature infants during intensive care.	in 51 sick newborns the influence of two different nonionic, iodine-containing contrast agents, amipaque (group 1) and omnipaque (group 2) and of long-term treatment with polyvinylpyrrolidone-iodine (pvp-i) (group 3) on thyroid function was studied. in the dose given, freshly dissolved amipaque releases roughly 100 micrograms 'free' iodide/kg body weight; this release may be even higher in the solubilized agent omnipaque because of increased breakdown. urinary iodine excretion was elevated in al ...	1987	3447940
[study on prostaglandin e involved in tooth movement--immunohistochemical observation].		1987	3475379
redifferentiation and subsequent dedifferentiation of the livers of roosters resulting from acute estrogen challenges.	1. histologic and metabolic changes take place in livers of rooster receiving challenges consisting of acute doses of estrone. 2. during initial growth and redifferentiation livers rapidly increase in size by division of hepatocytes within most lobules, changing from cordlike to acinar configurations. 3. no new lobules appear and degeneration of some cells within lobules takes place even as cell divisions predominate. 4. cells within lobules assume secretory features. 5. vitellogenins, very low ...	1987	2887384
human milk-derived lactoferrin inhibits mitogen and alloantigen induced human lymphocyte proliferation.	purified lactoferrin (lf), isolated from human milk, was tested for its effect on human t-lymphocyte proliferative responses to phytohemagglutinin (pha) and to alloantigens in mixed lymphocyte culture. lf inhibited proliferation in both assays in a dose-dependent manner. the suppressive effect was not due to lf mediated cytotoxicity since washing cells that had been pre-incubated with lf restored their proliferative activity. lf was most effective in suppressing the pha response when added withi ...	1987	2963123
selective translation initiation on bicistronic simian virus 40 late mrna.	we described previously a simian virus 40 (sv40) mutant, psvadl, that was defective in synthesis of the late viral protein vp1. this mutant, which contains a 100-base-pair fragment of adenovirus dna encompassing the major late promoter inserted in the sv40 late promoter region (sv40 nucleotide 294), efficiently synthesizes agnoprotein, a protein encoded by the leader region of the same mrna that encodes vp1. when the agnoprotein aug initiation codon in psvadl was mutated to uug, agnoprotein synt ...	1987	3035232
genetic relatedness of the kemerovo serogroup viruses: i. rna-rna blot hybridization and gene reassortment in vitro of the kemerovo serocomplex.	the dsrna profiles of the czechoslovakian and siberian serotypes of the kemerovo serocomplex viruses examined were similar in agarose, while their dsrna profiles were distinct in polyacrylamide gel. blot hybridization studies of the kemerovo serocomplex viruses demonstrated that the genes were highly conserved among the members within each type, but not between types. gene reassortment in vitro was demonstrated among selected pairs of the kemerovo serocomplex viruses by intra- and inter-typic cr ...	1988	2904730
two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance.	insulin receptor complementary dna has been cloned from an insulin-resistant patient with leprechaunism whose receptors exhibited multiple abnormalities in insulin binding. the patient is a compound heterozygote, having inherited two different mutant alleles of the insulin receptor gene. one allele contains a missense mutation encoding the substitution of glutamic acid for lysine at position 460 in the alpha subunit of the receptor. the second allele has a nonsense mutation causing premature cha ...	1988	2834824
effect of cck antagonists cr 1409 and cr 1505 on rat pancreatic exocrine secretion in vivo.	the action of cholecystokinin (cck) antagonists cr 1409 and cr 1505 on pancreatic exocrine secretion stimulated by exogenous and endogenous cck was studied in vivo in anesthetized rats, and compared with proglumide. intravenous administration of cr 1409 and cr 1505 in graded doses between 0.04 and 25 mg/kg/h resulted in a dose-dependent inhibition in pancreatic juice volume and amylase output stimulated by intravenous infusion of cck-8 in a dose of 0.06 microgram/kg/h. cr 1409 is 1,000 times and ...	1989	2813333
effect of cck antagonists cr 1409 and cr 1505 on rat pancreatic exocrine secretion in vivo.	the action of cholecystokinin (cck) antagonists cr 1409 and cr 1505 on pancreatic exocrine secretion stimulated by exogenous and endogenous cck was studied in vivo in anesthetized rats, and compared with proglumide. intravenous administration of cr 1409 and cr 1505 in graded doses between 0.04 and 25 mg/kg/h resulted in a dose-dependent inhibition in pancreatic juice volume and amylase output stimulated by intravenous infusion of cck-8 in a dose of 0.06 microgram/kg/h. cr 1409 is 1,000 times and ...	1989	2813333
gut perforation after infection with herpes simplex virus and epstein-barr virus.		1989	2570271
experimental studies on some effects of prostaglandin e2 in acute renal failure.	acute renal failure has been produced in rats with oral administration of uranyl nitrate 40 mg/kg of body weight once, and histopathological changes in the kidneys with blood biochemical values were studied by sacrificing them after 36 hours of feeding. prostaglandin e2 in 100 micrograms/kg of body weight was orally administered to another group of rats along with uranyl nitrate 40 mg/kg of body weight once and sacrificed them 36 hours after feeding. it was found that prostaglandin e2 has some p ...	1990	2362130
effects of maternal undernutrition and exercise on glucose kinetics in fetal sheep.	fetal glucose kinetics were measured using a combination of isotope-dilution and fick-principle methodology in single-pregnant ewes which were either well-fed throughout, or fed at 0.3-0.4 predicted energy requirement for 7-21 d during late pregnancy. all ewes were studied while standing at rest and then while walking on a treadmill at 0.7 m/s on a 10 degree slope for 60 min. underfed ewes suffered major decreases in fetal total disposal rate, fetal-placental transfer and umbilical net uptake of ...	1990	2223747
effects of maternal undernutrition and exercise on glucose kinetics in fetal sheep.	fetal glucose kinetics were measured using a combination of isotope-dilution and fick-principle methodology in single-pregnant ewes which were either well-fed throughout, or fed at 0.3-0.4 predicted energy requirement for 7-21 d during late pregnancy. all ewes were studied while standing at rest and then while walking on a treadmill at 0.7 m/s on a 10 degree slope for 60 min. underfed ewes suffered major decreases in fetal total disposal rate, fetal-placental transfer and umbilical net uptake of ...	1990	2223747
[nsf's extraordinary national assembly: marathon run with exciting final spurt].		2007	1863510
[measurement of orthodontic appliance force using prototype sensors].	in introductory remarks the most important biomechanical principles, which are relevant for the research, and conditions which must be satisfied presented in intraoral measuring of orthodontic forces were pointed out. first the aim of the research was defined, and then the investigation of mechanical properties of acrylics as a material for orthodontic appliances were carried out. the type of strain gauges, bonds and measuring system configurations, as well as measuring amplifiers and recording ...	2008	2635572
immediate reconstruction after mastectomy: team approach.	a review of 198 cases of breast reconstruction done at the time of mastectomy for carcinoma of the breast shows an extremely low morbidity. the technique of using a tissue-expander prosthesis enables immediate breast reconstruction without any fear of impairing prognosis, of spreading disease, or of impeding adjuvant therapy.	2008	2398784
non-synaptic release from dense-cored vesicles occurs at all terminal types in crayfish neuropile.	in the crayfish neuropile, dense-cored vesicles (dcv) have been found in chemical terminals, mixed in with round or pleomorphic agranular synaptic vesicles, as well as in electrical terminals and neurohemal endings. dcv release their content at unspecialized non-synaptic sites. the simultaneous exocytosis of dcv and synaptic vesicles seems to be the rule in chemical terminals. dcv in specific terminals suggest non-synaptic communication. in chemical and electrical terminals, the content of dcv c ...	2009	2702493
how it all started: new zealand's first open heart operation.		2009	2671838
aids: not the only infectious killer.		2009	2761978
[long-term follow-up of vena cava filters: real-time sonography and the native x-ray image].	in 16 patients with vena cava filters (12 günther filters, 4 kimray-greenfield filters) a follow-up study was performed by ultrasound and abdominal plain film. ultrasound allows to identify type and location of the filter as well as the entrapment of emboli. abdominal radiography is useful for exact evaluation of changes in filter position. combination of sonography and plain films is considered to be most suitable for follow-up studies of caval filters.	2009	3035643
incidence and causes of sepsis in glucose-6-phosphate dehydrogenase-deficient newborn infants.	to determine the susceptibility to sepsis in newborn infants deficient in glucose-6-phosphate dehydrogenase (g6pd), we screened 33,943 saudi arab infants. deficiency of g6pd was found in 18%. sepsis was determined by the presence of clinical signs of sepsis and confirmed by positive blood cultures. sepsis was documented in 75 infants (2.2/1000). the incidence of sepsis was significantly higher in 6138 g6pd-deficient infants (3.4/1000) than in the 27,805 with normal g6pd activity (1.9/1000; p les ...	2009	2715888
[current approaches to immunological diagnosis of autoimmune and immune complex diseases].		2010	2974642
cell surface heparan sulphate implicated in haemopoietic growth factor signalling.		2010	2978375
appearance of nerve growth factor receptors on cultured neural crest cells.	light microscopic radioautography of differentiating quail neural crest cultures (1 to 2 weeks after explanation) incubated with iodine-125-labeled nerve growth factor (125i-ngf) revealed that approximately 35% of the cells bound ngf. the binding was specific and saturable; it was blocked by an excess of nonradioactive ngf, and was not detected following incubation with biologically inactive 125i-ngf. in addition, the binding did not appear to be blocked or diminished by insulin. cell cultures p ...	2010	2996958
[ameloblastic fibroma: clinico-pathologic analysis].		2011	3150331
oesophageal pain exacerbated by propranolol.		2011	3113570
photodynamic therapy--lots of questions but presently few answers.		2011	3193473
ketamine tolerance.		2012	3255931
[iq and oligophrenia--a further health myth].		2012	4106359
[iq and oligophrenia--a further health myth].		2012	4106359
[application of professor machtou's compactors].		2012	3482391
[surgical treatment of primary chronic pancreatitis].	surgical methods of treatment of chronic alcoholic pancreatitis must be chosen with special reference to the state of the duct and parenchyma of the pancreas. treatment of alcoholic patients should be performed with the participation of psychiatrists.	2012	3424549
[the newborn infant of the mother with essential arterial hypertension ].		2013	3954855
management of pulmonary atresia with intact ventricular septum.	infants with pulmonary atresia and intact ventricular septum pose a difficult clinical problem. pulmonary valvotomy has been widely recommended for relief of the right ventricular obstruction, and most infants also have had an aortopulmonary shunt placed to ensure pulmonary blood flow. we have evolved a different approach that includes placement of a right ventricular outflow tract patch initially and continuation of prostaglandin e1 infusion postoperatively until the need for a shunt can be det ...	2013	3762200
surgical treatment of acute, massive lung embolism. results and follow-up.	between 1970 and 1984 the diagnosis of acute, massive lung embolism was made 30 times in our department. in 29 patients the clinical diagnosis was correct and a trendelenburg operation under extra-corporeal circulation was performed. in 18 cases there was an operation in the immediate preoperative course. in 1 case there was a combination of operation and the use of contraceptives. 3 cases were immobilized by a plaster of paris cast. in 4 cases the use of oral contraceptives and in 3 patients th ...	2013	3716720
language-specific and language-general in developing syntax.		2013	3745338
[diagnostic value of sonography, computerized tomography and lymphography in malignant lymphoma].		2014	3894181
light microscopy of indian ink preparations of fibrillated cartilage.		2014	4117785
[operative management of esophageal perforations].		2014	4017775
[clinical efficacy of selective phototherapy of psoriasis patients].		2014	4090681
the phenothiazines.		2015	4612601
vitamin b absorption in intestinal diseases (coeliac disease, dermatitis herpetiformis, ulcerative colitis, crohn's disease, jejuno-ileal shunting).		2015	4530459