Publications

etiology of oroya fever : i. cultivation of bartonella bacilliformis.	a pure culture of a microorganism resembling in morphology and pathogenic action bartonella bacilliformis has been obtained from blood taken during life from a case of oroya fever which ended fatally. the blood taken at lima into citrate solution and transported to new york at refrigerator temperature yielded positive cultures 28 days after its withdrawal from the patient. the strain of bartonella bacilliformis thus isolated grows well on the semisolid leptospira medium, and also on slant agar c ...	1926	19869166
etiology of oroya fever : ii. viability of bartonella bacilliformis in cultures and in the preserved blood and an excised nodule of macacus rhesus.	1. animals immunized with the formalinized filtrates of young toxic cultures of b. botulinus produce an antitoxic serum poor in precipitins. 2. animals immunized with the formalinized filtrates of old and partly autolyzed toxic cultures produce an antitoxic serum containing precipitins. 3. animals immunized with toxin-free autolyzed bacteria produce a serum free from antitoxin but rich in specific precipitins. 4. animals immunized with the filtrates of an atoxic variant produce a serum free from ...	1926	19869204
etiology of oroya fever : iii. the behavior of bartonella bacilliformis in macacus rhesus.	the experiments reported here were carried on in the main with passage strains of bartonella bacilliformis, and the results indicate that the virulence of the organism has been considerably enhanced by passage through susceptible animals. while the animals of the earlier experimental series showed no anemia, some of the present group manifested a definite reduction in the number of red cells and in hemoglobin, and in one instance (m. rhesus 25) anemia was of the extreme type so often associated ...	1926	19869217
etiology of oroya fever : iv. the effect of inoculation of anthropoid apes with bartonella bacilliformis.	the inoculation of a chimpanzee with cultures and a passage strain of bartonella bacilliformis induced local reactions which, while definite and characteristic, progressed less rapidly and were much less striking than those in the control rhesus monkey. bartonella bacilliformis was demonstrated in the blood corpuscles with difficulty, and the fever was slight compared with the high and persistent fever of the rhesus monkey. in both the swelling of the lymph glands was an early symptom and consta ...	1926	19869218
etiology of oroya fever : v. the experimental transmission of bartonella bacilliformis by ticks (dermacentor andersoni).	experiments are reported in which bartonella bacilliformis was transmitted from infected to normal rhesus monkeys by the bite of the tick, dermacentor andersoni. a long period of feeding, both on the infected animal and on the normal animal subjected to infection, was required in order to secure positive results. the infection transmitted by the ticks was mild, but definite, as shown by the recovery of bartonella bacilliformis from the lymph nodes and blood.	1926	19869219
the etiology of verruga peruana.	a saline suspension of a subcutaneous nodule excised from a verruga patient, and kept in the refrigerator for 14 days, on inoculation into two young macacus rhesus monkeys (nos. 33 and 34) induced irregular febrile reactions and enlargement of the lymph glands, and in one instance a subcutaneous nodule arose, independently of direct inoculation, on the tail. a microorganism has been isolated from the blood of both animals, and from the experimental nodule, which in pathogenic properties and in c ...	1927	19869238
etiology of oroya fever : vi. pathological changes observed in animals experimentally infected with bartonella bacilliformis. the distribution of the parasites in the tissues.	the pathological changes observed in the organs in macacus rhesus monkeys which have succumbed to severe infection with bartonella bacilliformis are similar to those found in human organs in persons dying of oroya fever. the characteristic changes in the liver are the zonal necrosis of the cells around the hepatic veins, involving active macrophagocytosis of invading polymorphonuclear leucocytes in the necrotic areas, and a marked endothelial hyperplasia in the sinusoids or around the portal vei ...	1927	19869264
etiology of oroya fever : vii. the response of the skin of macacus rhesus and anthropoid apes to inoculation with bartonella bacilliformis.	bartonella bacilliformis failed to induce lesions when merely rubbed on the surface of the intact skin of a chimpanzee, an ourang-utan, and numerous macacus rhesus monkeys, although when applied to the scarified skin of the same animals it gave rise to extensive lesions. application of infectious material to the scarified skin did not always induce verruga lesions, but intradermal inoculation almost invariably gave rise to nodule formation. the localization of bartonella bacilliformis in the ski ...	1927	19869265
etiology of oroya fever : viii. experiments on cross-immunity between oroya fever and verruga peruana.	nine monkeys (macacus rhesus) and a chimpanzee which had recently recovered from an infection with the oroya strain of bartonella bacilliformis were tested for immunity against the verruga strain of bartonella bacilliformis as well as against the homologous strain. complete immunity to both strains was demonstrated. the result establishes the identity of the strains and is in agreement with the result of comparative serological study. the criteria of recovery include not only the subsidence of f ...	1927	19869288
etiology of oroya fever : ix. bacterium peruvianum, n. sp., a secondary invader of the lesions of verruga peruana.	a minute, pleomorphic, motile, gram-negative bacterium has been isolated from two specimens of nodular tissue from human verruga. in films and sections of the original tissues the organism in question is difficult to distinguish from bartonella bacilliformis, with which it was associated, and even in pure culture it has a number of properties in common with that parasite. no sugars are fermented by it, it is an obligate aerobe, the optimum temperature for its growth is 25 degrees c., and it has ...	1928	19869395
etiology of oroya fever : x. comparative studies of different strains of bartonella bacilliformis, with special reference to the relationship between the clinical types of carrion's disease and the virulence of the infecting organism.	through the cooperation of dr. sebastian lorente, director of the national department of public health of peru, nine strains of bartonella bacilliformis have been isolated, by means of the semisolid leptospira medium, from nine of twelve specimens of blood withdrawn from cases of verruga and forwarded from peru under conditions of refrigeration. the cultural titer of the blood specimens immediately after their arrival (2 weeks after withdrawal) varied from 1:10 to 1:100,000. blood from the sever ...	1928	19869408
etiology of oroya fever : xi. comparison of bartonella bacilliformis and bartonella muris. cultivation of bacterium murium, n. sp.	bartonella muris appeared in the blood of all white rats, wild rats, chinese hamster, and mice, from which the spleen was removed, but did not appear in that of splenectomized monkeys, rabbits, or guinea pigs. it has not been possible to transmit b. muris to normal rats, monkeys, rabbits, or guinea pigs, by intraperitoneal, intradermal, or intravenous injection of blood containing b. muris from splenectomized rats. in two instances an acute orchitis was induced in normal rats by injection direct ...	1928	19869409
etiology of oroya fever : xii. influence of malarial infection (plasmodium inui?), splenectomy, or both, upon experimental carrion's disease in monkeys.	the experiments reported were designed to determine the influence of malarial infection (plasmodium inui?), splenectomy, or both combined, upon the course and character of experimental infection with bartonella bacilliformis in monkeys (macacus rhesus and m. cynomolgus). blood withdrawn from a monkey showing spontaneous malarial infection was inoculated intravenously into monkeys (a) 1 month prior to inoculation with virulent verruga material, (b) simultaneously with the verruga material, and (c ...	1928	19869445
etiology of oroya fever : xiii. chemotherapy in experimental bartonella bacilliformis infection.	the therapeutic effect of several antiparasitic chemicals on experimental verruga peruana is described. the drugs were administered by intravenous injection according as the nodules (1) were already developed to an approximate maximum, or (2) were still in the active period of growth. the effect of the drugs was different under the two circumstances of their administration. when they were given after the maturity of the nodules they hastened the regressive process, but when given during active g ...	1928	19869508
etiology of oroya fever : xiv. the insect vectors of carrion's disease.	with a view to determining the mode of infection in carrion's disease, a study of the blood-sucking insects found in the districts of peru where the disease prevails has been carried out, through the cooperation of the rockefeller institute and the rockefeller foundation. the material studied included ticks, mites, midges, lice, fleas, bedbugs, mosquitoes, buffalo gnats, horse-flies, "sheep ticks," 3 species of streblidae, and 3 species of phlebotomus, including phlebotomus verrucarum townsend a ...	1929	19869598
etiology of oroya fever : xv. effect of immune serum on the course of bartonella bacilliformis infection in macacus rhesus.	experiments are reported on the effect upon the course of experimental verruga peruana in macacus rhesus of the injection of (1) small quantities of rabbit immune serum simultaneously with living cultures, (2) one large dose of convalescent monkey serum 24 hours prior to inoculation, (3) a similar preliminary dose followed by three subsequent injections of the serum, (4) three large doses of convalescent serum, following the inoculation. the convalescent serum was found (1) to prevent the multip ...	1929	19869628
etiology of oroya fever : xvi. verruga in the dog and the donkey.	in the experiments here reported, definite verruga lesions, in which the presence of bartonella bacilliformis was established by culture or by passage to rhesus monkeys, were produced in a dog and in a donkey by inoculation of cultures or monkey passage strains. the reaction induced in these animals was entirely local, however; blood cultures were sterile. histologically, the lesions produced were similar to those obtained in monkeys by inoculation of bartonella bacilliformis, except for the pre ...	1929	19869639
the effect of the x-ray on the nodules of verruga peruana.	the supposition that x-ray would affect the developing and the developed verruga nodules experimentally induced in the monkey, has proved correct. the experiments show that the early verruga nodules when exposed to a single, properly graduated dose of x-ray producing merely erythema of the skin, are inhibited in their evolution. moreover, the skin of macacus rhesus monkeys is modified by a single erythema dose of x-ray in such a way that infection of it with bartonella bacilliformis is rendered ...	1930	19869674
the bartonella and related parasites in man and animals (oroya fever and verruga peruviana): (section of tropical diseases and parasitology).	through the investigations of noguchi on the one hand, and mayer and kikuth on the other, the unity of the aetiology of oroya fever and verruga peruviana has been demonstrated experimentally. the bartonella bacilliformis, the causal organism of oroya fever, belongs to a group of micro-organisms, the parasitic nature of which has been definitely proved during the last few years. tests with a view to transmitting the disease to monkeys, and the aetiology, clinical data, pathology, therapy and immu ...	1934	19989875
demonstration of agglutinins for bartonella bacilliformis.	1. methods of preparing a satisfactory antigen having been developed, a technique for performing an agglutination test with b. bacilliformis is made available. 2. as a result of repeated intravenous injection of living cultures of b. bacilliformis at short intervals, rabbits have been found to produce a high titre of specific agglutinins which, under the conditions obtaining in the present series of experiments, begins to decline after about one month following the last inoculation. 3. sera from ...	1942	19871168
bartonella bacilliformis anemia (oroya fever); a study of 30 cases.		1948	18875365
complement fixation and weil-felix reaction in rabbits inoculated with bartonella bacilliformis.		1950	14794897
[new investigations on bartonella bacilliformis. i. morphology of cultured variety].		1952	14951682
[new investigations on bartonella bacilliformis. ii. effects of sulfonamides & antibiotics in vitro].		1952	14959269
carrión's disease. i. studies on plants claimed to be reservoirs of bartonella bacilliformis.		1953	13065631
carrión's disease. ii. presence of bartonella bacilliformis in the peripheral blood of patients with the benign form.		1953	13065632
[further research on bartonella bacilliformis. iii. experiments with rhesus monkeys and body lice on transmissibility of the disease].		1953	13079109
[new studies on bartonelle bacilliformis. 4. electron-optical study of blood smears containing bartonella bacilliformis].		1953	13137391
[carrion's disease; trial experimental infection of white mouse with intranasal inoculation of bartonella bacilliformis].		1957	13460670
[carrion's disease; morphological study of bartonella bacilliformis by electron microscope].		1957	13460671
[carrion's disease; bartonella bacilliformis resistance to lyophilization].		1957	13460686
[superposed culture method for bartonella bacilliformis].		1966	5995786
hyper-reactivity of rabbits sensitized with bartonella bacilliformis.	mitchell, paul d. (west virginia university medical center, morgantown), and john m. slack. hyper-reactivity of rabbits sensitized with bartonella bacilliformis. j. bacteriol. 92:769-779. 1966.-sensitization with viable cells of bartonella bacilliformis increased the susceptibility of rabbits to the lethality of subsequently administered bartonella metabolites. in animals sensitized with 3 weekly doses of the organism, this susceptible state of hyper-reactivity was maximal between 4 and 14 days ...	1966	4958777
characterization of two different agglutinators in the latex fixation test, occurring in normal human sera.		1966	4160336
experimental transmission of a murine microsporidian in swiss mice.	the production of ascitic fluid and splenomegaly on intraperitoneal injection in weanlings was used as a test for microsporidia after introduction by other routes and in other loci. oral and cerebral administration was followed only by enlarged spleens which reproduced the ascitic response on passage. microsporidia were demonstrable by phase microscopy in all fluids. positive findings were also obtained with liver, kidney, brain, lungs, blood, and urine. intramuscular and intranasal injection we ...	1967	4862191
simple measures for removing the toxic factors from lathyrus sativus.		1967	4864206
amphotericin b inhibition of active pah transport.		1968	4231363
the relationship of bartonella bacilliformis to the red blood cell as revealed by electron microscopy.		1969	5779156
[growth of bartonella bacilliformis in superimposed gels].		1970	5276315
supraventricular arrhythmia with abnormal qrs complex.		1972	5035977
experimental papilledema in the dog induced by a salicylanilide.		1972	5047050
relationship between antihistamine and antidepressant activity in hexahydroindenopyridines.		1972	4402485
[properties that characterize the erythrocyte factors required by bartonella bacilliformis for its growth].		1972	4516163
virus induced alterations on some properties of fowl erythrocyte membrane.		1972	4645191
persistent truncus arteriosus in a newborn pig.		1972	4672615
[molecular weight of serum interferon induced by the newcastle disease virus in high and low producer mice].		1972	4676284
human growth hormone secretion after double stimulation with arginine in normal and insulin-dependent diabetic women.		1973	4728208
house fly control in climate-controlled caged-hen layer houses.		1973	4732615
[anti-brain antibodies in the presence of stress].		1973	4798250
[study of the dynamics of the quantitative and qualitative changes in the cellular composition of the milk during the early lactation period].		1973	4593541
substrate specificity and kinetic studies on thiogalactoside transacetylase.		1973	4630409
[carrion's disease: useful nutrients for the growth of bartonella bacilliformis].		1973	4519947
[verruga peruana. evaluation of bartonella bacilliformis nutrients in gel].		1974	4527596
controlled variation of microtubule number in neuronal processes during remodelling in vivo.		1974	4426355
proceedings: an electrophysiological analysis of action of piracetam in rats.		1974	4450996
the role of protein synthesis in adrenocorticotrophin action: effects of cycloheximide and puromycin on the steroidogenic response of isolated adrenocortical cells.		1974	4376095
determination of estrogens in pregnancy urine by hemoagglutination inhibition reaction.	a simple and rapid hemoagglutination inhibition reaction system for the estimation of estrogens in pregnancy urine is described. results obtained by this method showed a good correlation with those measure by a conventional radioimmunoassay method and brown's colorimetric method. ninety-seven pregnancy urine samples from various gestational weeks were subjected to the assay, and the usefulness of this method as a screening test for high-risk pregnancy is discussed.	1975	173188
maintenance of spermatogenesis with testosterone or dihydrotestosterone in hypophysectomized rats.		1975	1151927
developmental patterns of peripheral nerve, myoneural junction and muscle: a review.		1977	148071
[presence of the parasite bartonella bacilliformis in the blood and its recovery in thymectomized mice. strains: 049, 35, 12 and 15].		1977	279054
the fetus, pregnancy and parturition.		1977	98095
[latex-chagestest-reactions of immunsera against bartonella bacilliformis, haemobartonella muris and eperythrozoon coccoides (author's transl)].	sera from 10 patients positive for carrion's disease were analysed by means of the latex chagas test. sera from 40 spf-rats experimentally infected with haemobartonella muris and 5 spf-mice experimentally infected with eperythrozoon coccoides were similarly tested. both the human and mice sera were negative whereas positive reaction was observed with rat sera. the nature of this positive reaction has not been clarified.	1977	888185
naturally occurring diatomaceous pneumoconiosis in sub-human primates.		1978	96157
effects of nitroglycerin on cardiac function and regional blood flow distribution in conscious dogs.	the effects of intravenous infusion of nitroglycerin (ntg), 8 and 32 microgram/kg.min for 7 min, and of sublingual ntg, 1.2 mg, were examined on direct and continuous measurements of systemic, coronary, and regional hemodynamics, left ventricular (lv) dimensions, pressures, and myocardial contractility in conscious dogs. ntg induced sustained reductions in lv dimensions and transient increases in heart rate and dp/dt, and decreases in mean arterial pressure. initially ntg increased cardiac outpu ...	1978	415619
kinetics of in vitro bovine lymphocyte immunostimulation with a brucella abortus antigen.	a brucella abortus-soluble antigen was investigated, using in vitro assay of lymphocyte immunostimulation, to determine which concentration of this antigen and which period of incubation of the lymphocyte cultures would induce maximum specific lymphocyte immunostimulation as an additional method for further study of b abortus infection in cattle. soluble antigen was prepared from autoclaved cells of b abortus strain 1119-3. peripheral blood lymphocytes were obtained from cattle infected with b a ...	1978	415646
anti-actin antibodies of human and rabbit origin.	the production of actin antisera in rabbits was described and their reaction in various immunological tests were compared with the results obtained with human anti-actin sera (smooth muscle antibodies). even if the sera may react with different antigenic determinants of actin as suggested by results in immunoprecipitation and blocking experiments, the rabbit and human sera can be used for studies of cells with equal or similar results. a prerequisite was that the rabbit anti-actin titres were hi ...	1978	98096
immunofluorescence and electron microscopic studies on kidney, choroid plexus and pituitary in rhesus monkeys immunized with the anti-hcg vaccine pr-beta-hcg-tt.		1978	98291
aerosolized antigen dose-response studies in asthmatic monkeys.	this study used rhesus monkeys which had consistent respiratory responses to a standard (single dose) aerosolized concentration of a. beginning at lower concentrations of a which did not produce an airway response, fourfold increases in concentrations of a were aerosolized until an airway response occurred. compared with the single-dose sac after the tac, some consistently reactive animals did not respond to the sac, the maximal concentration of a used for testing. thus the tac may result in an ...	1978	98604
immunochemical analysis of the conformational properties of intermediates trapped in the folding and unfolding of bovine pancreatic trypsin inhibitor.		1978	98640
differential tolerance to pentobarbital in rats bred for differences in alcohol sensitivity.	two lines of rats bred for differences in motor impairment following alcohol treatment were also found to be differentially affected by sodium pentobarbital in three experiments. the most affected (ma) animals, bred for sensitivity to alcohol, showed a decrement in stabilimeter activity at doses of 8 mg and 16 mg pentobarbital per kg body weight. the least affected (la) animals, bred for insensivity to alcohol, were affected only by the higher dose, at which the resulting impairment was still le ...	1978	98785
peptide hydrolases of lactobacillus casei: isolation and general properties of various peptidase activities.	discovery of an endopeptidase by gel chromatography and separation of 3 exopeptidases (a dipeptidase, an aminopeptidase and a specific carboxypeptidase) from lactobacillus casei ncdo 151 by affinity chromatography is described. the 3 exopeptidases were strongly inhibited by the metal chelators edta and 1,10-phenanthroline but were reactivated with co2+ and mn2+. the ph optima for aminopeptidase, dipeptidase and carboxypeptidase activities were 6.5, 7.6 and 7.2, respectively. maximum activity was ...	1978	101561
biochemical genetics of macaques. ii. glucosephosphate isomerase polymorphism in rhesus monkeys.		1978	103539
congenital defects due to hyperthermia.		1978	104560
chlorpyrifos and 3,5,6-trichloro-2-pyridinol: residues in the body tissues of cattle wearing chlorpyrifos-impregnated plastic ear bands.		1978	84823
potentiating effect of nitrate and other anions on contraction in vascular smooth muscle.		1978	87173
radioimmunoassay for the detection and quantitation of 5-fluorodexoyuridine.	a sensitive radioimmunoassay for 5-fluorodeoxyuridine (fdurd) and 5-fluoro-2'-deoxyuridine 5'-monophosphate has been developed by using antibody induced in rabbits, [3h]fdurd, and a separation technique with nitrocellulose filters. antibody specificity was characterized by using compounds chemically related to fdurd and comparing their effectiveness for displacing [3h]fdurd from the antibody-combining site. drug levels in serum samples from patients receiving fdurd chemotherapy were easily and r ...	1978	148966
guinea-worm infection in banaskantha district of gujarat--some important epidemiological aspects.		1978	153328
the purification of orotidine-5'-phosphate decarboxylase from yeast by affinity chromatography.	we have prepared an affinity column for the purification of orotidine-5'-phosphate decarboxylase from yeast. the column effects a 3200-fold purification from yeast homogenate in one pass; simple additional steps produce enzyme that has been purified 6700-fold and is not contaminated by any other protein that can be detected by sodium dodecyl sulfate-acrylamide gel electrophoresis. overall, 35% of the activity present in the yeast is recovered as pure enzyme. the resin for the column is synthesiz ...	1979	374408
plotting the milky way.		1979	257577
influenza virus split vaccines. effect of priming infection on serologic response in humans.		1979	262510
influence of temperature on isometric contractions of rabbit atria during inotropic interventions.	inotropic effects on strips of left atria promoted by 1-epinephrine, increase in frequency, post-extrasystolic potentiation, and by increase in extracellular calcium concentration were studied at 28 c and 36 c. the results show that at lower temperature the resulting changes in temporal parameters (activation time, deactivation time and duration above 10% of maximum force) are greater than those at the higher temperature. at 36 c inotropic interventions have more prominent effects on the tension ...	1979	263167
immunologic studies of native and modified human factor viii/von willebrand factor.	factor viii/von willebrand factor (fviii/vwf) is a glycoprotein with a molecular weight greater than one-million daltons. two activities are associated with this large molecule: fviii procoagulant activity and vwf activity. incubation of fviii/vwf with proteolytic enzymes causes rapid inactivation of the fviii procoagulant activity but has little effect on the vwf activity or antigenicity. in an attempt to gain insight into the structural features required for these two activities, antisera were ...	1979	88237
separation of human leukocyte interferon components by concanavalin a-agarose affinity chromatography and their characterization.	human leukocyte interferon (hl-if), produced by mixed leukocytes infected with newcastle disease virus, was resolved into three distinct fractions when chromatographed on concanavalin a-agarose. the major portion (70--75%) of interferon appeared in the breakthrough (bt fraction). the bound interferon (25--30%) was displaced from the column as two peaks: the first was eluted with 0.01 m methyl alpha-d-mannoside, yielding 15-20% of the interferon activity (alpha-mm fraction), and the second by inc ...	1979	92998
deficiency of the ninth component of complement in man.	the studies of serum from a case with c9 (the ninth component of complement) deficiency are described. a 29-year-old woman in good health was found to have low serum complement levels (ch50). c9 of her serum was undetectable by the hemolytic assay and by the immunochemical analysis but all other components were normal. it was demonstrated that low ch50 of her serum was due to the hemolysis of the sensitized sheep erythrocytes (ea) by the complement components from c1 to c8.	1979	95812
[the adrenergic innervation of the thoracic lymphatic duct in dogs in postnatal ontogeny].	using histochemical fluorescence technique, studies have been made on the adrenergic innervation of the wall of the thoracal lymphatic duct in postnatal development of puppies. adrenergic fibers were found in the adventitial layer of the duct. during postnatal development of the animals, adrenergic innervation of this duct becomes more perfect, reaching the level of adult animals to the age of 2-3 months.	1979	95857
[role of anti-brain antibodies in the development of mineralocorticoid deficiency].		1979	85292
[relationship of the structure of specific somatic antigen polysaccharides in shigella dysenteriae bacteriae to the immunochemical properties].		1979	85516
preganglionic neurons in the sacral spinal cord of the rat: an hrp study.		1979	86176
effects of antiprostatic agents on 5alpha-dihydrotestosterone binding to rat hypophyseal and hypothalamic cytosol macromolecules.	the binding of 5alpha-dihydrotestosterone to the hypophyseal and hypothalamic cytosol macromolecules prepared from castrated male rats was observed. the effects of antiprostatic agents on 5alpha-dihydrotestosterone binding to both hypophyseal and hypothalamic cytosol macromolecules was examined. cyproterone acetate and chlormadionone acetate showed the significant inhibiting effects on 5alpha-dihydrotestosterone binding to 7-8 s macromolecules of cytosol from both hypophysis and hypothalamus. sc ...	1979	86441
penicillin-resistant gonorrhea.		1979	106997
[sarcocystis and toxoplasma infections in slaughter sheep in bavaria].		1979	107950
persistence of ketosis despite suppression of lipolysis by 16,16-dimethylprostaglandin e2 in experimental diabetic ketoacidosis in rats.		1979	113273
the effect of cortisol on the response of the depolarized, calcium-free mouse uterus to calcium [proceedings].		1979	497599
bartonella bacilliformis: colonial types and erythrocyte adherence.	bartonella bacilliformis was cultivated on a solid medium, and two bartonella colonial morphologies were differentiated and designated colony types t1 and t2. although both t1 and t2 bartonellae adhered to human erythrocytes in vitro, approximately twice as many t2 bartonellae adhered as did t1. maximum adherence required bartonella energy, most likely proton motive force-dependent motility. bartonellae did not penetrate or lyse erythrocytes in vitro. bartonellae adhered poorly to alpha- or beta ...	1981	7012005
demonstration of a ouabainlike plasma compound in hypertension prone and hypertension resistant rats.	material extracted and partially purified from plasma of the sabra hypertension prone rats was found to be capable of 1) inhibiting the binding of 3h-ouabain to rat brain synaptosomes, 2) inhibiting the activity of rat brain microsomal na, k activated adenosine triphosphatase, and 3) increasing the contractile force of rat heart muscle. the results demonstrate the presence of a ouabainlike compound in the plasma of these rats. the plasma concentration of this compound in sabra hypertension prone ...	1985	2993163
regulated biosynthesis and divergent metabolism of three forms of hepatic apolipoprotein b in the rat.	studies using rat livers perfused with recycled, serum-containing medium plus [3h]leucine revealed that secreted vldl contain three forms of apolipoprotein b (apob), b-48, b-95, and b-100, all synthesized by the liver. the b-48/(b-95 + b-100) [3h]leucine incorporation ratio ranged from 0.22 to 3.25 with livers of rats fed different diets, and the ratio was positively correlated with the triglyceride secretion rate in most of the livers. generally, as more triglyceride was secreted, a greater pro ...	1985	3973514
cardiovascular effects of drugs acting on the autonomous nervous system, in awake, normotensive and hypertensive rats.	a study has been carried out in awake normotensive (wky), spontaneously hypertensive (shr) and renal hypertensive (rhr) rats in order to compare the reactivity of the autonomous nervous system using different indwelling catheterizations. in all cases, a jugular catheter was implanted for i.v. injections. the arterial cannula was implanted in the femoral artery (group 1) or in the right carotid artery (group 2), where the catheter was routed over 20 mm towards the heart, reaching the aortic arch. ...	1985	4015261
cerebellocerebral projection from the fastigial nucleus onto the frontal cortex in the cat.	two frontal cortical areas hidden in sulci were found to be responsive to stimulation of the cerebellar fastigial nucleus under pentobarbital anesthesia: one is the ventral bank of the cruciate sulcus and the other is the area surrounding the fundus of the presylvian sulcus which corresponds to subregions of the frontal eye field. the fastigial projection onto these areas via the thalamic ventromedial (vm) nucleus was identified electrophysiologically and morphologically.	1985	4063817
plasmodium falciparum malaria: band 3 as a possible receptor during invasion of human erythrocytes.	human erythrocyte band 3, a major membrane-spanning protein, was purified and incorporated into liposomes. these liposomes, at nanomolar concentrations of protein, inhibited invasion of human erythrocytes in vitro by the malaria parasite plasmodium falciparum. liposomes containing human band 3 were ten times more effective in inhibiting invasion than those with pig band 3 and six times more effective than liposomes containing human erythrocyte glycophorin. liposomes alone or liposomes containing ...	1985	3880920
antibodies to bartonella bacilliformis as determined by fluorescence antibody test, indirect haemagglutination and elisa.	two strains of bartonella bacilliformis were cultured on columbia agar supplemented with 5% defibrinated human blood. antigens prepared from these cultures were used for determination of antibodies by fluorescence antibody test (fat) indirect haemagglutination (iha) and an enzyme immunoassay (elisa). one hundred and eighty-seven human sera from b. bacilliformis-endemic areas of peru were tested of which 63.6% were reactive. elisa was the most sensitive test, followed by fat and iha. igm antibody ...	1985	3911360