Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| significance of campylobacter pylori. | there is an explosion of interest in the role of campylobacter pylori as a cause of active chronic gastritis. this curved spiraled microorganism can readily be detected within the mucus gel covering the stomach mucosa, especially in patients suffering from peptic ulcer disease or non-ulcer dyspepsia. to what extent this intriguing microorganism is causally related to peptic ulcer disease remains to be elucidated, but all the evidence which is available so far supports a pathogenetically importan ... | 1987 | 2979701 |
| problems with clinical trials on campylobacter pylori. | clinical trials investigating campylobacter pylori infection have proven difficult to conduct and to interpret. those trials examining the relapse rates of duodenal ulcer disease among subjects in whom c. pylori infection has been eradicated have shown a significant reduction in recurrence rates. however, since the bismuthate compounds used in these trials have cytoprotective ulcer-healing properties, reduced relapse rates cannot be attributed to antibiotic activity alone. those trials examining ... | 1988 | 2980756 |
| [the urease test for the diagnosis of campylobacter pylori infection]. | to evaluate the usefulness of urea media routinely applied in the diagnosis of campylobacter pylori infection, 50 patients with gastroduodenal pathology were studied. two biopsies of antral mucosa were taken; one of them was placed on urea agar base (difco) prepared without agar, and the other in saline for gram staining and culture in selective and enriched media. in 39 patients campylobacter pylori was found by gram staining and/or culture. 38 of them were urease test positive, 24 (61.5%) duri ... | 1989 | 2485236 |
| campylobacter pylori in upper digestive tract diseases in children. | results of studies on the frequency of the occurrence of the bacteria, campylobacter pylori, in the mucous membrane of the gastric antrum are presented in this paper. the study was carried out on 61 children treated for chronic abdominal pain. the diagnosis was established on the basis of flexible endoscopy and histology of antral biopsies. the presence of campylobacter pylori was determined using the clo-test. the positive clo-test was obtained in 87.5% of children with gastritis, in 75% of chi ... | 1989 | 2489238 |
| [in vitro activity of 16 antimicrobial agents against helicobacter (campylobacter) pylori]. | campylobacter pylori has been associated with the etiology of gastritis and duodenal ulcer. it has been shown that several drugs, among them a variety of antimicrobials, eliminate c. pylori from gastric mucosa at least for a time, resulting in an improvement of the patients' symptoms. the activity of 16 antimicrobials (ampicillin, cefazolin, cefuroxime, cefotaxime, imipenem, aztreonam, tigemonam, erythromycin, vancomycin, nalidixic acid, colistin , norfloxacin, ciprofloxacin, difloxacin, ofloxac ... | 1989 | 2490433 |
| [pathogenicity of campylobacter pylori in the digestive tract]. | 1989 | 2490635 | |
| [campylobacter pylori's sensitivity to the bactericidal action of human serum]. | the sensitivity to the bactericidal power of the human serum was evaluated on 8 strains of c. pylori, 8 strains of c. jejuni, 2 strains of c. coli and 2 strains of c. fetus. each of them was incubated at 37 degrees c in the presence of a complete pool of human sera, the same pool after inactivation of the complement, and trypticase soy broth (control). after 0, 15, 30 and 60 minutes the capacity to grow in blood agar plates (count of colonies) incubated in microaerophillic conditions for 3 days ... | 1989 | 2490652 |
| animal models for campylobacter pylori infection. | 1989 | 2490934 | |
| campylobacter pylori absence in extragastric human intestinal sites and animal stomachs. | 1989 | 2491306 | |
| [campylobacter pylori and the gastric mucosa. apropos of the detection of campylobacter pylori in 12 patients with gastric mucosa lesions]. | the authors report the results of systematic research on campylobacter pylori during high endoscopy. of the 60 patients examined, 12 were found to have the germ in their antral, gastric mucosa. all these patients had a history of chronic gastritis. they recall the role of this germ in creating chronic gastritis, and evoke the hypothesis that the mucosa becomes fragile facilitating the appearance of an ulcer. | 1989 | 2491383 |
| antral helicobacter pylori, hypergastrinaemia, and duodenal ulcers: effect of eradicating the organism. | 1989 | 2514864 | |
| campylobacter pylori infection and gastric mucosal lesions in patients with chronic liver diseases. | 1989 | 2519092 | |
| [isolation of campylobacter pylori from gastric biopsies in people from the south of chile]. | 1989 | 2519366 | |
| [frequency of campylobacter pylori in apparently healthy and asymptomatic venezuelans]. | we evaluated 21 healthy asymptomatic venezuelan volunteers free of risk factors for gastritis with upper gastrointestinal endoscopy, and four antral biopsies: a)2 for histological examinations, b) urease test, c) culture and gram coloration. 13 out of 21 subjects were positive for campylobacter pylori (61.30%) all of them had chronic gastritis and in the negative cases 7 were considered histologically normal. urease test was positive in 12/13 with a sensitivity of 92% and 100% specificity. frequ ... | 1989 | 2535448 |
| [comparison of urease test (clotest) and histology in the diagnosis of campylobacter pylori]. | campylobacter pylori has been implicated in the pathogenesis of peptic ulcer, non-ulcer dyspepsia and chronic gastritis. c. pylori produces large amounts of urease which has been used as a biochemical support to identify the microorganism. in this study, we described the use of a rapid urease test (clotest) to detect c. pylori. in 46 consecutive patients, biopsy of fundus and antrum were obtained for histology and clotest. all specimens showed chronic gastritis. in 22 patients (48%) c. pylori wa ... | 1989 | 2535449 |
| campylobacter pylori becomes helicobacter pylori. | 1989 | 2572746 | |
| evidence of gastritis with several helicobacter pylori strains. | 1989 | 2574351 | |
| omeprazole, helicobacter pylori, gastritis, and duodenal ulcer. | 1989 | 2574352 | |
| [helicobacter pylori-induced cost-benefit risk considerations]. | 1989 | 2575693 | |
| prevalence of helicobacter pylori infection and histologic gastritis in asymptomatic persons. | we estimated the prevalences of helicobacter pylori (formerly called campylobacter pylori) infection and histologic gastritis in 113 asymptomatic persons, using endoscopic biopsy of the gastric antrum and corpus. unsuspected lesions, mainly mucosal erosions, were revealed at endoscopy in 16 subjects (14 percent). gastritis was found in 42 subjects (37 percent), of whom 36 (32 percent of the total) were found to be infected with h. pylori on the basis of hematoxylin-eosin staining. h. pylori was ... | 1989 | 2586553 |
| isolation of campylobacter pylori in patients with non-ulcer dyspepsia. | 1989 | 16312293 | |
| in vitro antibacterial activity of rifaximin against campylobacter pylori (campylobacter pyloridis). | 1989 | 16312378 | |
| colloidal bismuth subcitrate (de-nol) and tinidazole healed duodenal ulceration with a low relapse rate due to elimination of campylobacter pylori. | 1989 | 16312662 | |
| comparison of four stains and a urease test for rapid detection of helicobacter pylori in gastric biopsies. | gastric biopsies were obtained from 125 subjects to compare detection of helicobacter pylori by culture, a rapid urease test and histopathologic examination using haematoxylin-eosin, gram, giemsa, warthin-starry silver and acridine orange stains. helicobacter pylori was isolated from 39 specimens. acridine orange and giemsa were the most sensitive stains, detecting 85% and 79% of positive specimens respectively. all stains showed high specificity (97-100%). the sensitivity and specificity of the ... | 1990 | 1695573 |
| comparison of culture and histology for the identification of helicobacter pylori in endoscopic biopsies. | the aim of the study was to compare culture with microscopic examination of haematoxylin and eosin stained tissue sections in the identification of helicobacter pylori in gastric antral mucosa. duplicate gastric antral biopsies from 89 patients were cultured and examined histologically for h pylori. h pylori was cultured in 46 cases (51%) and identified histologically in 63 (71%). results from the two tests concurred in 63 cases (71%). the presence of h pylori was strongly correlated with histol ... | 1990 | 1697451 |
| use of dna restriction endonuclease digest and ribosomal rna gene probe patterns to fingerprint helicobacter pylori and helicobacter mustelae isolated from human and animal hosts. | variation amongst strains of helicobacter pylori and helicobacter mustelae was examined by dna restriction endonuclease digestion and rrna gene patterns generated using a non-radioactive probe. chromosomal dna was extracted from 30 cultures of h. pylori from human, rhesus monkey and pig gastric mucosa, and from three h. mustelae isolates from ferret gastric mucosa. dna fingerprinting with hae iii and hind iii showed h. mustelae was relatively homogeneous but revealed genomic heterogeneity within ... | 1990 | 1698260 |
| detection of antibodies to helicobacter pylori cell surface antigens. | serum igg antibodies of helicobacter pylori were detected in single-dilution elisa using glycine extracted material. among 148 endoscopy patients 59% displayed antibodies; as expected, a higher occurrence (90%) was found in patients with positive gastric culture for h. pylori than in culture negative patients (37%). among 68 blood donors the frequency of h. pylori antibodies was 28%. in 73 children less than 15 years of age examined for unrelated disorders the occurrence was 4%. by immunoblottin ... | 1990 | 1699265 |
| a spiral microorganism in the stomach of pigs. | light and electron microscopic and microbiologic evaluations were performed on mucosa of stomachs from 120 healthy slaughtered pigs. helicobacter pylori was not found, but a tightly spiralled bacterium, not previously described, was seen in histological sections and/or in carbol fuchsin stained smears in 13 (10.8%) stomachs. in paraffin sections stained with carbol fuchsin, the bacteria were seen in the mucus of the lumen of the antral pits and in the mucosa surface within and beneath the mucus. ... | 1990 | 1700535 |
| comparison of sensitivity and specificity of three different methods for the detection of helicobacter pylori infection. | 1990 | 1701286 | |
| superior stain for helicobacter pylori using toluidine o. | 1990 | 1702103 | |
| different effect of helicobacter pylori on the human gastric antral and body mucosal intracellular mucin. | to elucidate the role of helicobacter pylori infection in the pathogenesis of gastric ulcer, we investigated the intracellular mucin content by measuring the periodic acid-schiff-alcian blue (pas-ab)-stained substances, by means of computer, in the biopsy sample of gastric mucosa from patients with and without h. pylori infection. in the antral mucosa the intracellular pas-ab-stained mucin content was significantly smaller in patients with infection than in patients without infection, whereas in ... | 1990 | 1702231 |
| direct gram stain and urease test to detect helicobacter pylori. | antral biopsies were obtained by gastrointestinal endoscopy on 143 adult patients with dyspeptic symptoms of gastritis or peptic ulcer disease. a direct gram stain and a direct urease test were performed on each biopsy in addition to culture. forty-three biopsies (30%) were considered positive for helicobacter pylori based on culture or histologic examination, or both. thirty-one biopsies (72% sensitivity) were positive for both direct tests, whereas 95 of 100 negative cultures were negative for ... | 1990 | 1703938 |
| direct detection and amplification of helicobacter pylori ribosomal 16s gene segments from gastric endoscopic biopsies. | helicobacter pylori is an organism thought to play an important causative role in gastritis and peptic ulcer diseases. we have designed an rna dot blot assay for the detection of h. pylori, using as probe a synthetic oligonucleotide complementary to its 16s rrna. we have also used oligonucleotide primers, complementary to conserved sequences within bacterial ribosomal 16s genes, to amplify a h. pylori ribosomal 16s dna fragment via the polymerase chain reaction (pcr). after determining the dna s ... | 1990 | 1703940 |
| [the determination of c. pylori in patients with gastroduodenal diseases]. | a total of 46 gastric mucosa biopsy specimens obtained during surgery and 90 gastric juice samples from patients with gastroduodenal diseases were examined. campylobacter-like microorganisms were detected in 84.6 percent of biopsy specimens and in 73.9 percent of gastric juice samples (in gram-stained smears). urease activity was detected in 75.9 and 13.3 percent, respectively. c. pylori growth in solid nutrient medium in microaerophilic conditions was observed in 44.2 and 5.7 percent of the exa ... | 1990 | 1704468 |
| rapid diagnosis of campylobacter pylori infection by urea test paper. | antral biopsy specimens from 106 patients were examined by culture, gram stain and silver stain for campylobacter pylori. biopsies were also examined by a urea test paper test (utpt). of 106 patients studied c. pylori was detected in 68 (64.2%) by gram stain, silver stain and culture. the utpt was positive in 63 (59.4%) specimens. five had false negative results using the utpt with no false positive subjects. thus, utpt has a sensitivity of 92.6% (63/68) and a specificity of 100%. of the 63 spec ... | 1990 | 1717032 |
| hypothesis: helicobacter pylori, urease, mucus, and gastric ulcer. | ammonia, released in the gastric mucosa by the action of helicobacter pylori urease on transuded plasma urea, curtails the biosynthesis of mucus and/or causes the mucus to be disassembled at the mucosal surface. these changes facilitate colonisation by h pylori and may promote gastric ulcer formation. | 1990 | 1967668 |
| metronidazole-resistant helicobacter pylori. | 1990 | 1968548 | |
| helicobacter gastritis and intestinal metaplasia in a gastric cancer family. | 1990 | 1969086 | |
| helicobacter pylori, mucus, and gastric ulcer. | 1990 | 1969087 | |
| metronidazole resistance in helicobacter pylori. | 1990 | 1970050 | |
| helicobacter pylori acid resistance. | 1990 | 1971083 | |
| cure of duodenal ulcer associated with eradication of helicobacter pylori. | 50 patients with intractable duodenal ulcer were randomly assigned to 4 weeks of treatment with colloidal bismuth subcitrate (cbs) alone (26 patients) or with amoxicillin and metronidazole (24 patients). 5 patients (all on triple therapy) withdrew because of side-effects. in 17 of the 45 patients who completed the treatment, helicobacter pylori was eradicated, and there was no ulcer relapse during the first 12 months of follow-up. the ulcer relapse rate was significantly higher (17 of 21 [89%]) ... | 1990 | 1971318 |
| in vitro killing of helicobacter pylori with photodynamic therapy. | 1990 | 1971363 | |
| helicobacter pylori and hiv infection. | 1990 | 1972223 | |
| cure of peptic ulcer associated with eradication of helicobacter pylori. | 1990 | 1972523 | |
| vaccination against helicobacter pylori urease. | 1990 | 1973509 | |
| cure of duodenal ulcer after eradication of helicobacter pylori. | eighty-two patients, whose duodenal ulcers were recurrent or resistant to h2-receptor antagonist therapy, were entered in a treatment protocol of ranitidine followed by a four-week "triple therapy" course to eradicate helicobacter pylori (hp) infection. the triple therapy consisted of colloidal bismuth subcitrate, tetracycline and metronidazole. duodenal ulcer healed in all 78 patients available for endoscopy and h. pylori infection was shown to be eliminated in 75 patients (96%) at rebiopsy fou ... | 1990 | 1974027 |
| mixed gastric infection by gastrospirillum hominis and helicobacter pylori. | 1990 | 1975013 | |
| antibodies to helicobacter pylori in hiv infection. | 1990 | 1975069 | |
| treatment of helicobacter pylori positive duodenal ulcers. | 1990 | 1975930 | |
| gastroenterologists in sydney--histology and helicobacter. | 1990 | 1976150 | |
| gastroduodenal pathology and helicobacter pylori. third workshop of the european helicobacter pylori study group. proceedings. | 1990 | 1977429 | |
| therapy in helicobacter pylori infection. | 1990 | 1978187 | |
| acid and barriers. current research and future developments for peptic ulcer therapy. | medical therapy for peptic ulcer disease has been targeted at inhibiting acid secretion based on the belief that ulcers occur due to an imbalance between aggressive and protective factors. new antisecretory agents are unlikely to show any dramatic improvement over the success and safety of histamine h2 receptor antagonists or the recently introduced h+k+atpase proton pump antagonist omeprazole. the development of specific muscarinic m3 and gastrin receptor antagonists will provide useful agents ... | 1990 | 1978405 |
| pathogenesis and therapy of peptic ulcer disease. | the epithelial cells of the stomach and duodenum are normally protected from the damaging effects of acid and pepsin by a balancing mechanism of mucosal resistance. if an imbalance occurs, peptic ulcer may result. traditional teaching has emphasized the importance of acid (and pepsin) as the cause of this imbalance; however, it is clear that acid and pepsin are not the only important factors in the pathogenesis of peptic ulcer. more recent investigative efforts have been directed at what constit ... | 1990 | 1978840 |
| helicobacter pylori and metronidazole resistance. | 1990 | 1978897 | |
| sydney classification for gastritis and helicobacter pylori. | 1990 | 1978898 | |
| inhibition of helicobacter pylori by acetohydroxamic acid. | 1990 | 1979397 | |
| epidemiology and treatment of gastric campylobacter pylori infection: more questions than answers. | two-hundred and ten consecutive patients undergoing routine gastroscopy were additionally investigated for evidence of campylobacter pylori (c.p.). 106 patients were positive in one or more tests: 99.1% using a rapid urease detecting test (clo-test), 80.2% histology, 78.3% cytology and 60% culture. we found no difference between the clo-test results from biopsies taken from different parts of the stomach in individual patients. c.p. was found in 100% of patients with significant chronic antral g ... | 1990 | 1982107 |
| determinants of acid secretion. | acid secretion is regulated by hormonal factors acting peripherally and centrally, as well as neural factors. gastrin and histamine are the two most important peripheral hormonal stimulants, while the vagus is the predominant nerve affecting acid secretion. meal related acid secretion occurs in three phases: cephalic, gastric and intestinal. acid secretion is stimulated in the first two phases while it is inhibited in the intestinal phase. proteins are potent acid stimulants but carbohydrates an ... | 1990 | 1982628 |
| site-and cytoprotective drugs in the short-term treatment of peptic ulcer. what is their current role? | many endoscopically controlled comparisons with h2-blockers have widely documented that site- and cytoprotective drugs constitute effective and safe agents for the short-term treatment of gastric and duodenal ulcer. their efficacy however, is counter-acted by the need for multiple daily administration which requires greater patient compliance. due to its ability to eradicate helicobacter pylori (hp) from the gastric antrum and retard relapses, colloidal bismuth may be the first choice anti-ulcer ... | 1990 | 1983422 |
| helicobacter pylori and gastric carcinoma. | a retrospective study was performed on gastric carcinomas to establish the prevalence of helicobacter pylori infection in gastric epithelium adjacent to the tumour. a total of 105 carcinomas were studied. the overall prevalence of helicobacter pylori infection was 59%. the prevalence in different age cohorts from patients with gastric carcinoma was compared with that in patients suffering from non-ulcer dyspepsia and, based on serological testing, with that in healthy blood donors. the presence ... | 1990 | 2076886 |
| gastroduodenal mucosa in uraemia: endoscopic and histological correlation and prevalence of helicobacter-like organisms. | this study aimed to determine the prevalence of endoscopic and histological gastroduodenitis as well as helicobacter-like organisms in patients with end stage renal failure undergoing maintenance dialysis treatment. a total of 322 out of 422 patients in our dialysis programme underwent endoscopy and gastroduodenal biopsy specimens were taken from 260. endoscopic gastroduodenitis occurred in 158 (49%). histological gastritis occurred in the gastric body or antrum in 134 patients (52%) and duodeni ... | 1990 | 2083853 |
| synergism between clindamycin and colloidal bismuth subcitrate against helicobacter (campylobacter) pylori in vitro. | a combination of clindamycin and colloidal bismuth subcitrate was evaluated for synergistic inhibition of helicobacter pylori employing the agar dilution method. a total of 47 clinical isolates of helicobacter pylori were examined. synergistic interaction was observed in 36%, additive behaviour in 64% of the strains. no antagonism could be detected. | 1990 | 2085373 |
| campylobacter peritonitis in a capd patient. | 1990 | 2085566 | |
| activity of cefixime against helicobacter pylori and affinities for the penicillin-binding proteins. | cefixime induced the formation of rounded cells from the spiral bacillary form of helicobacter pylori at the mic or less. three main penicillin-binding proteins, called a, b and c, were separated from h. pylori. cefixime had the strongest affinity to penicillin-binding protein b. the binding of cefixime to this protein may induce the formation of rounded h. pylori cells. | 1990 | 2088199 |
| [characteristics of helicobacter (campylobacter) pylori infection in our field]. | the presence of helicobacter pylori in the stomach in patients with clinical signs of gastroduodenal disease and its possible relationship with several clinical, endoscopic and anatomopathologic characteristics of the illness were prospectively evaluated in 359 patients. h. pylori was isolated from 388 samples in 216 patients (60% of colonization). in patients with endoscopic and, or, anatomopathologic evidence of gastroduodenal alterations the microorganism was isolated in 67% of the instances ... | 1990 | 2089203 |
| detection of helicobacter pylori in gastric brushings. | 1990 | 2091356 | |
| [t-lymphocytes of the gastric mucosa in peptic ulcer]. | chronic ulcer edges and pylorus of 6 stomachs removed because of ulcer and 10 biopsies of the stomach pylorus from patients with duodenal ulcer were studied. t-helpers and t-suppressors (cytotoxic) were revealed by the indirect three-step immunoperoxidase method with the use of monoclonal antibodies okt-4 and okt-8, respectively. t-suppressors (cytotoxic) prevailed among interepithelial gastric lymphocytes in both normal conditions and ulcer. t-helpers dominated in the mucosa tunica propria. the ... | 1990 | 2091578 |
| [detection of campylobacter pylori in gastric mucosa--relation to gastroscopy findings and degree of gastritis]. | in 862 unselected gastroscopies we could confirm the high percentage of campylobacter pylori infection in the antral gastric mucosa strongly associated with chronic superficial gastritis and active inflammatory signs. significant correlation with age concerned the normal findings only. in patients with duodenal ulcers we found in 91% gastritis and in 88% campylobacter pylori in antral mucosa. a small group with duodenal ulcers was campylobacter pylori-negative as well as without gastritis signs. ... | 1990 | 2091669 |
| comparison of four different methods for detection of helicobacter pylori from gastric biopsies. | helicobacter pylori are commonly found colonizing the gastric mucosa of different populations. its presence may be important in the pathogenesis of gastritis and peptic ulcer disease. the detection rates vary widely depending upon the diagnostic methods applied. in this study, multiple gastric biopsies were taken from the fundal and antral mucosa of 25 patients during endoscopy. in one patient, the procedure was repeated about two months after the initial biopsy. a total of 52 sets of specimens ... | 1990 | 2091902 |
| the aetiology of peptic ulcer--"debugging" an enigma and its impact on therapy. | 1990 | 2092019 | |
| relative merits of various rapid biopsy urease tests for diagnosis of helicobacter pylori (campylobacter pylori). | three rapid urease tests, i.e., liquid urea broth containing phenol red as indicator, liquid urea broth containing bromothymol blue as indicator and clo gel were compared in 109 patients of dyspepsia for the diagnosis of campylobacter pylori (helicobacter pylori) infection. mean time taken for positive reaction in liquid broth with phenol was 3 minutes (range 0.6 to 5.3 minutes) with bromothymol blue was 3.5 minutes (range 0.4 to 5.5 minutes) while with clo gel it was 101 minutes (range 11-261 m ... | 1990 | 2092020 |
| unusual features of helicobacter (campylobacter) pylori--associated gastritis in india. a study of 200 cases. | helicobacter (campylobacter) pylori has been cultured from the antral biopsies of 85-90% of patients of gastritis, gastric ulcer and duodenal ulcer at different centres. studies conducted all over the world have firmly implicated this organism in the aetiology of active superficial gastritis and recurrences of duodenal ulcer. two hundred patients with upper abdominal pain, distension, vomiting and/or haemetemesis were subjected to ogd scopy. in 163 of these patients there was endoscopic evidence ... | 1990 | 2092022 |
| association of peptic ulcer with helicobacter pylori and the recurrence rate. a three year follow-up study. | helicobacter pylori is associated with 70-100% of peptic ulcers. relapse of infection has been shown to cause recurrences of ulcers in a large number of studies. we diagnosed 137 cases of peptic ulcer (121 du; 16 gu) during a 3 year period. of these, 117 were positive for h pylori. sixty six of the 117 cases staying in the vicinity of the hospital were followed up for a minimum period of 3 months upto a maximum period of 3 years. in 91 examinations there was relapse of h pylori infection and ulc ... | 1990 | 2092024 |
| relapse of helicobacter pylori infection after different treatment regimens. a 3-month follow-up study. | helicobacter pylori infection of gastric antrum is associated with a majority of cases of peptic ulcer (70-100%). studies have shown that when this organism is eradicated, the recurrence of ulcer falls to less than one-third of those in whom the infection persists or relapses. monotherapy with bismuth salts, tinidazone or amoxycillin has been shown to result in early relapse and recurrence of ulcers. however, dual or triple therapy regimens are more effective. we conducted a randomised controlle ... | 1990 | 2092026 |
| is maintenance therapy required for duodenal ulcer disease? | 1990 | 2092032 | |
| does helicobacter pylori play a role in the pathogenesis of peptic ulcer? part i: no. helicobacter pylori is a commensal in the stomach. | 1990 | 2092033 | |
| does helicobacter pylori play a role in the pathogenesis of peptic ulcer? part ii. yes, helicobacter pylori is a pathogenetic factor in peptic ulcer. | 1990 | 2092034 | |
| [biochemical, physiological, and enzymatic study of 78 strains of helicobacter (campylobacter) pylori isolated from gastroduodenal biopsies]. | a biochemical, physiological and enzymatic study of 78 c. pylori strains isolated from gastroduodenal biopsies is reported. all strains were positive in the oxidase, catalase and urease tests. 97.4% produced sh2 in the lead acetate band and 79.4% showed beta-hemolytic activity in sheep blood agar. in the antibiotic selection tests, c. pylori was characterized to be resistant to nalidixic acid and sensitive to cefalotin . the enzymatic study demonstrated the presence of acid and alkaline phosphat ... | 1990 | 2094388 |
| [comparative study of campylobacter pyloridis and campylobacter jejuni under electron microscope]. | specimens were made by preparing the ultrathin sections after negative staining and ruthenium red staining. the specimens were observed under electron microscope. results revealed that the shapes of campylobacter pyloridis (cp) and c. jejuni (cj) were similar, but distinctive differences in their structures were observed. cp had one to five sheathed flagella at one end with bulbous tips. cj had only one unsheathed flagellum on each end without a bulbous tip. the cell body of cp was longer than t ... | 1990 | 2094635 |
| [helicobacter pylori and gastro-duodenal pathology]. | helicobacter pylori (hp) were found in 878 (73%) of 1205 patients undergoing upper g-i endoscopy with multiple biopsies for gastroduodenal diseases. hp were present in similar percentages among patients with active (89%) or healed (81%) peptic ulcer as well as in non ulcerous dyspeptics affected with gastritis (85%). 96% of active chronic gastritis were infected by hp as compared with 55% of quiescent gastritis. antral gastritis was more frequently active in patients with ulcer diseases (76%) th ... | 1990 | 2094841 |
| adherence of helicobacter pylori cells and their surface components to hela cell membranes. | four helicobacter pylori strains were used to develop in vitro methods to assess adherence to hela cells. using direct detection by microscopy, adhesion scores increased with the initial bacteria-to-cell ratio. the urease method assessed h. pylori bound to hela cells by their urease activity. the percentage of the original inoculum adhering to hela cells remained constant for initial ratios from 10(2) to 10(5) bacteria per cell. an elisa using anti-h. pylori serum assessed whole bacteria or comp ... | 1990 | 2097496 |
| helicobacter pylori--our knowledge is growing. | 1990 | 2099416 | |
| detection of helicobacter pylori from endoscopic biopsies and the biochemical characteristics of these isolates. | helicobacter pylori (formerly campylobacter pylori) has been recently described as a gastritis-associated bacterium. we examined endoscopic biopsies of 100 patients with dyspepsia and found h. pylori in the gastric antrum of 34 (34%) by either culture, urease tests and/or histology. thirty-one out of 41 patients (75.6%) confirmed to have chronic active gastritis histologically had h. pylori in their gastric antrum compared to 3 out of 59 patients (5.1%) with dyspepsia but normal histology (p les ... | 1990 | 2102969 |
| campylobacter pylori infection: experience in a multiracial population. | over a 15-month period, 399 patients with dyspepsia were investigated for the presence of campylobacter pylori infection. half of the patients (50.6%) had campylobacter organisms in the antrum of the stomach. c. pylori was found in 96.1% of patients with histological changes of chronic active gastritis in the antrum. of patients with duodenal and gastric ulcers, 87.8% and 87.5%, respectively, had campylobacter organisms, as did 39.3% of patients with non-ulcer dyspepsia. c. pylori infection was ... | 1990 | 2103410 |
| histological identification of helicobacter pylori in early and advanced gastric cancer. | 1990 | 2103734 | |
| gastric histology and plasma gastrin response to a meal in patients with duodenal ulcer disease after five years treatment with ranitidine. | fifty asymptomatic patients with duodenal ulcer disease, aged 31-82 years, who had received ranitidine maintenance therapy continuously for five or more years without a symptomatic recurrence, were studied. fasting plasma gastrin concentrations were normal (mean 24 pmol/l, s.d. +/- 22) while the post-prandial gastrin response was variable with maximum plasma concentrations ranging from 16 to 309 pmol/l. endoscopy revealed six asymptomatic peptic ulcers. histological examination of gastric biopsi ... | 1990 | 2103756 |
| dosage of colloidal bismuth subcitrate in duodenal ulcer healing and clearance of campylobacter pylori. | sixty consecutive patients with endoscopically proven duodenal ulcers were given colloidal bismuth subcitrate tablets either as 120 mg q.d.s. or 240 mg b.d., in a randomized single-blind study. the efficacy of each regimen was determined by endoscopic examination and antral biopsy at 4 weeks; if the ulcer remained unhealed, treatment was continued and endoscopy repeated at 8 weeks. the ulcer-healing efficacy of the two regimens was identical; however, in the four times daily group only 27% remai ... | 1990 | 2104073 |
| the interaction between helicobacter pylori culture filtrate and indomethacin: effects on the integrity of human gastric antral mucosa and its prostaglandin e2 production in vitro. | histopathological methods and radioimmunoassay were used to assess the microstructure and prostaglandin e2 production by paired specimens of human gastric antral mucosa; the specimens were studied after 48 h of incubation in base-line tissue culture medium, helicobacter pylori culture filtrate, h. pylori culture control fluid, indomethacin, and h. pylori culture filtrate plus indomethacin. when applied alone, the filtrate did not affect the structure of the mucosal tissue or its prostaglandin e2 ... | 1990 | 2104089 |
| [campylobacter (helicobacter) pylori-induced cost effectiveness-risk considerations]. | 1990 | 2107370 | |
| helicobacter pylori in gastroduodenal disease. | helicobacter pylori is a recently described gram-negative micro-organism, which plays an important role in the pathogenesis of peptic ulcer disease and gastritis. in this paper an outline is given of the history and the pathophysiology of helicobacter pylori, as well as the therapeutic studies aimed at eradication of the bacterium in various clinical entities. | 1990 | 2110652 |
| unsaturated fatty acids and viability of helicobacter (campylobacter) pylori. | helicobacter (campylobacter) pylori was found to be sensitive to the toxic effects of an unsaturated fatty acid (arachidonic acid). data are presented that support the hypothesis that exogenous catalase added to basal media enhances the growth of h. pylori by preventing the formation of toxic peroxidation products from long-chain unsaturated fatty acids. | 1990 | 2112559 |
| hydrophobic characterisation of helicobacter (campylobacter) pylori. | cell-surface hydrophobicity of helicobacter (formerly campylobacter) pylori was tested by aqueous two-phase partitioning and hydrophobic interaction chromatography. the hydrophobicity of h. pylori greatly exceeded that of campylobacter fetus subsp. fetus, c. jejuni and bacillus subtilis. a partition coefficient (pc) of hydrophobicity in the two-phase system was determined for h. pylori. pc was dependent on ph and the pc value was increased by greater than 20-fold at ph 2.5. lithium cations incre ... | 1990 | 2113100 |
| the 14co2 urea breath test for helicobacter pylori infection. | 1990 | 2118567 | |
| association of helicobacter pylori with acid peptic disease in karachi. | the prevalence of h. pylori infection in 200 dyspeptic patients undergoing upper g.i. endoscopy was investigated by histology and rapid urease test. h. pylori was associated with 86% cases of chronic gastritis, 84.6% cases of duodenal ulcers and 78.5% of gastric ulcers. none of the 15 histologically normal gastric biopsies showed h. pylori. | 1990 | 2123260 |
| helicobacter pylori induces lymphocyte activation in peripheral blood cultures. | helicobacter pylori-induced in vitro stimulation of mononuclear cells was characterized by measuring dna synthesis response, interferon-gamma (ifn-gamma) secretion and the number of immunoglobulin-secreting cells. the strength of these responses was measured in 51 subjects comprising 36 dyspeptic patients from the gastroenterological unit and 15 members of the laboratory staff. nineteen subjects had antibodies to h. pylori and 32 did not. the responses were compared with respect to h. pylori ant ... | 1990 | 2124957 |
| validation of a simplified carbon-14-urea breath test for routine use for detecting helicobacter [correction of heliobacter] pylori noninvasively. | a carbon-14 (14c) urea breath test for detecting helicobacter pylori with multiple breath sampling was developed. carbon-14-urea (110 kbq) administered orally to 18 normal subjects and to 82 patients with helicobacter infection. the exhaled 14c-labeled co2 was trapped at 10-min intervals for 90 min. the total 14c activity exhaled over 90 min was integrated and expressed in %activity of the total dose given. in normals, a mean of 0.59% +/- 0.24% was measured, resulting in an upper limit of normal ... | 1990 | 2125066 |
| a placebo controlled trial of bismuth salicylate in helicobacter pylori associated gastritis. | in a placebo controlled prospective clinical trial of bismuth salicylate in helicobacter pylori associated gastritis, 52 adult patients were randomly allocated to treatment with bismuth salicylate or placebo. helicobacter pylori were totally cleared in 77% patients in bismuth group but none in placebo group (p less than 0.001). resolution of gastritis (p less than 0.001) and improvement of symptoms (p less than 0.01) were significantly better in patients where h. pylori infection cleared as comp ... | 1990 | 2125658 |
| helicobacter pylori associated chronic gastritis and peptic ulceration in patients taking non-steroidal anti-inflammatory drugs. | helicobacter pylori is now recognized as a frequent cause of histological chronic gastritis, and this has radically changed our understanding of this common condition. in the light of these developments, the traditional view that non-steroidal anti-inflammatory drugs are one of the common 'environmental' causes of chronic gastritis has been re-examined. gastric mucosal biopsies have been studied from 430 patients undergoing routine upper gastrointestinal endoscopy, 99 of whom had recently been t ... | 1990 | 2129639 |