Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| concerning the morphology and reproduction of spirochaeta pallida and a rapid method for staining the organism. | 1906 | 19867050 | |
| the distribution of treponema pallidum, schaudinn (spirochaeta pallida), in the tissues in congenital syphilis. | 1906 | 19971740 | |
| spirochaetosis of mice due to spirochaeta muris n.sp. in the blood. | 1906 | 20474291 | |
| on the spirochaeta pallida and its variations. | 1906 | 20762660 | |
| demonstration of the variations of the spirochæta pallida, etc. (epidiascope and microscope). | 1907 | 20897090 | |
| spirochaeta (treponema) pallida and syphilis. | 1907 | 19867104 | |
| a case of intra-uterine death of the foetus occurring in six consecutive pregnancies, with observations upon the importance of the examination of the foetal tissues for the presence of the spirochaeta pallida. | 1908 | 19973170 | |
| a case of intra-uterine death of the fœtus occurring in six consecutive pregnancies, with observations upon the importance of the examination of the fœtal tissues for the presence of the spirochæta pallida. | 1908 | 20897567 | |
| spirochaeta pallida: methods of examination and detection, especially by means of the dark ground illumination. | 1909 | 20764459 | |
| specimen of spirochæta pallida prepared with indian ink, with demonstration of method. | 1910 | 20898660 | |
| specimen of spirochaeta pallida prepared with indian ink, with demonstration of method. | 1910 | 19974263 | |
| the comparative neuropathology of trypanosome and spirochaete infections, with a résumé of our knowledge of human trypanosomiasis. | 1911 | 19975395 | |
| method for the pure cultivation of pathogenic treponema pallidum (spirochaeta pallida). | in conclusion, it may be pointed out that this is the first time that treponema pallidum of schaudinn has been proven beyond all doubt to have been obtained in pure culture. the method of cultivation described would appear also to be suitable for obtaining indefinite generations of the microorganism. doubtless slight modifications will adapt it to a larger number of strains and possibly to the cultivation of all strains and to still other species of treponema. finally, it may now be accepted as ... | 1911 | 19867465 |
| the comparative neuropathology of trypanosome and spirochæte infections, with a résumé of our knowledge of human trypanosomiasis. | 1911 | 20899792 | |
| pure cultivation of spirochaeta refringens. | a strain of spirochoeta refringens has been obtained in pure culture, and its morphological and cultural characteristics have been studied. the strain possessed no pathogenicity for rabbits or monkeys. it probably belongs to the genus treponema, but it is easily differentiated from treponema pallidum, treponema microdentium, and treponema macrodentium. its relation to spirochoeta balanitidis and spirochoeta buccalis is still undetermined. | 1912 | 19867539 |
| treponema mucosum (new species), a mucin-producing spirochaeta from pyorrhea alveolaris, grown in pure culture. | 1. a mucin-producing spirochoeta has been obtained in pure culture from a case of pyorrhea alveolaris. this organism is an independent species of the genus treponema and, as it is recognized for the first time, i propose for it the name treponema mucosum. 2. morphologically the mucosum is difficult to separate from the pallidum and microdentium, but, through its biological properties and animal reactions it is easily differentiated from all the rest of the spirochoetae. 3. the mucosum is not par ... | 1912 | 19867565 |
| the pure cultivation of spirochaeta duttoni, spirochaeta kochi, spirochaeta obermeieri, and spirochaeta novyi. | 1. a method for the pure cultivation of spirochoeta duttoni, spirochoeta kochi, spirochoeta obermeieri, and spirochoeta novyi is described in this paper. in vitro these strains reach their maximum growth after seven, eight, or nine days at 37 degrees c. for their multiplication they require the presence of a piece of fresh sterile tissue and a body fluid capable of forming a loose fibrin with the tissue. the presence of some oxygen seems indispensable for their growth, since they fail to grow in ... | 1912 | 19867566 |
| pure cultivation of spirochaeta phagedenis (new species), a spiral organism found in phagedenic lesions on human external genitalia. | 1. a hitherto undescribed spiral organism has been isolated in pure culture from a case of mild phagedenic ulcer on the external genitalia of a woman. for this organism the name spirochoeta phagedenis is proposed. 2. spirochoeta phagedenis is a strict anaerobe and grows in the presence of fresh tissue in ascitic agar. it produces no apparent change in the media, but a somewhat offensive odor develops in the culture tube. 3. spirochoeta phagedenis incites a slight inflammatory reaction in the ski ... | 1912 | 19867571 |
| a study of complement fixation in syphilis with spirochaeta culture antigens. | 1912 | 19867578 | |
| cultivation of spirochaeta gallinarum. | 1. spirochoeta gallinarum can be cultivated in suitable artificial media for many successive generations and probably for indefinite periods. the presence of fresh tissue and a certain amount of oxygen seems to be essential for its growth. no perceptible odor is produced in the cultures. 2. the maximum growth of spirochoeta gallinarum is reached on about the fifth day, but the phase of degeneration commences slowly and gradually, so that in this respect the gallinarum differs from the duttoni, k ... | 1912 | 19867601 |
| cultivation of treponema calligyrum (new species) from condylomata of man. | 1. on the surface of genital or anal lesions, either syphilitic or non-syphilitic, there may be found occasionally a spirochaeta resembling treponema pallidum, but somewhat thicker than the latter. in general characteristics, this organism occupies an intermediary position between treponema pallidum and spirochaeta refringens. 2. the treponema was obtained in pure culture from two cases. for the organism the name of treponema calligyrum is proposed. 3. treponema calligyrum is non-pathogenic for ... | 1913 | 19867628 |
| a study of the spirochaeticidal action of the serum of patients treated with salvarsan. | 1. the serum of rabbits treated intravenously with neosalvarsan, and of syphilitic patients treated intravenously with salvarsan or neosalvarsan, has a definite spirochaeticidal action upon spirochoeta duttoni. 2. although this spirochaeticidal action is exerted in vitro, it can be demonstrated only after the treated spirochaetae are injected into susceptible animals. 3. a curative action of the serum of neosalvarsan-treated rabbits is exercised on mice infected with spirochoeta duttoni. 4. the ... | 1913 | 19867719 |
| a new spirochaeta found in human blood. | 1913 | 19977210 | |
| a new spirochæta found in human blood. | 1913 | 20901607 | |
| observations on a strain of spirochaeta pallida isolated from the nervous system. | a strain of spirochoeta pallida isolated from the nervous system has shown the following constant characters: (1) thick form; (2) the production of hard, well demarcated lesions with necrotic centers; (3) a characteristic location of the lesion; (4) a short incubation period; (5) a tendency to generalize with lesions of the skin and eye, following local inoculation of the testicle and scrotum. it is suggested that these characters constitute a definite strain of highly invasive power and that a ... | 1914 | 19867775 |
| a pathological study of syphilitic aortitis and its serology. | 1. syphilitic aortitis is a productive inflammatory process, the earliest and most constant feature of which is a perivascular round cell infiltration in the adventitia. 2. the typical gross picture of luetic aortitis is often obscured by a superimposed, diffuse atherosclerosis. in the early cases the aorta appears fairly normal, presenting only the characteristic histological changes. 3. a pure aortic insufficient valve, with the exception of an infectious endocarditis, is always luetic. 4. car ... | 1916 | 19867969 |
| the pure cultivation of spirochaeta icterohaemorrhagiae (inada). | pure cultures of the spirochaetal causative agent of the disease known as weil's disease, or febrile icterus, in japan, have been obtained by us in a solid, a semisolid, and a fluid medium. the spirochaeta thus isolated remains pathogenic for guinea pigs for many generations. up to the present time we have succeeded through the courtesy of professor nagayo, dr. konuma, and dr. ishihara, in cultivating three different strains. the spirochaeta is a facultative anaerobe. the solid and semisolid cul ... | 1916 | 19868006 |
| the prophylaxis of weil's disease (spirochaetosis icterohaemorrhagica). | we have already described briefly the portals of entry and of excretion of the pathogenic spirochetes. we may mention here that we have twice prevented epidemics by disinfection of the ground and the removal of the inundated water in certain places in coal mines. in one mine 19 out of 50 workmen, and in another 9 out of 30 workmen came down with weil's disease in about 2 weeks. we have already pointed out that the period during which the pathogenic spirochetes are excreted in the urine continues ... | 1916 | 19868055 |
| the serum treatment of weil's disease (spirochaetosis icterohaemorrhagica). | horses immunized with cultures of spirochaeta icterohaemorrhagiae yield an immune serum having therapeutic properties. with rare exceptions the serum destroys completely the spirochetes contained in the circulating blood. the development of antibodies is promoted by the serum injections. the number of spirochetes in the organs is reduced by the treatment. secondary manifestations due to the serum are slight and disappear promptly. the ultimate effects of the serum treatment on the symptoms and f ... | 1916 | 19868056 |
| observations on spirochaeta eurygyrata, as found in human faeces. | 1916 | 20768165 | |
| spirochaeta morsus muris, n.sp., the cause of rat-bite fever : second paper. | 1. since our first report on the discovery of the cause of rat-bite fever, we have been able to prove the existence of the same spirochete in five out of six more cases which have come under our observation. 2. the clinical symptoms of rat-bite fever are inflammation of the bitten parts, paroxysms of fever of the relapsing type, swelling of the lymph glands, and eruption of the skin, all occurring after an incubation period usually of from 10 to 22 days, or longer. 3. our spirochete is present i ... | 1917 | 19868077 |
| the drug-fastness of spirochetes to arsenic, mercurial, and iodide compounds in vitro. | in the foregoing experiments we attempted to determine whether or not, by subjecting several varieties of spirochetes to increasing doses of certain chemotherapeutic agents, a gradual increase of resistance to the latter could be shown. for this purpose, pure cultures of treponema pallidum, treponema microdentium, and spirochoeta refringens were used against the action of salvarsan, neosalvarsan, bichloride of mercury, and iodine-iodide potassium solution in vitro. for culture media, the usual a ... | 1917 | 19868093 |
| spirochaeta icterohaemorrhagiae in american wild rats and its relation to the japanese and european strains : first paper. | the principal points brought out in the present article are the following. 1. wild rats captured in this country carry in their kidneys a spirochete which possesses the morphological and pathogenic properties characteristic of spirochata icterohamorrhagia discovered by inada in the japanese form of infectious jaundice. 2. cultures of the american, belgian, and japanese strains of the spirochete were obtained by a special technique described, the first two strains having been cultivated artificia ... | 1917 | 19868121 |
| cultivation of spirochaeta obermeieri. | 1917 | 19868132 | |
| the distribution in the human body of spirochaeta icterohaemorrhagiae. | 1917 | 19868152 | |
| the rat as a carrier of spirochaeta icterohaemorrhagiae, the causative agent of weil's disease (spirochaetosis icterohaemorrhagica). | 1. on the basis of these findings, we conclude that the extermination of rats and field mice is a highly important prophylactic measure against weil's disease. 2. the chemical composition of soil and water plays animportant part in the development of spirochoeta icterohoemorrhagioe, and consequently in the spread of the disease of which it is the causative agent. | 1917 | 19868153 |
| distribution of spirochaeta icterohaemorrhagiae in the organs after intravenous serum treatment. | on the basis of these findings we believe that we are justified in saying that the immune serum of weil's disease is capable of destroying the spirochetes found within the organs in man, with the exception of the kidneys, and that the action of the serum upon the spirochetes is spirochetolytic and spirocheticidal. the scattered spirochetes in the kidney, on the other hand, are resistant to the action of the immune serum. the spirochetes disappear almost completely from the organs during the conv ... | 1918 | 19868206 |
| morphological characteristics and nomenclature of leptospira (spirochaeta) icterohaemorrhagiae (inada and ido). | the present study deals with the morphology and systematic position of the causative agent of infectious jaundice. there are several features which are not found in any of the hitherto known genera of spirochaetoidea which led me to give this organism an independent generic name, leptospira, denoting the peculiar minute elementary spirals running throughout the body. the absence of a definite terminal flagellum or any flagella, and the remarkable flexibility of the terminal or caudal portion of ... | 1918 | 19868227 |
| further study on the cultural conditions of leptospira (spirochaeta) icterohaemorrhagiae. | 1. the presence of suitable animal or human serum is essential for the cultivation of leptospira icterohaemorrhagiae. 2. the nutrient value of serum is considerably reduced by heating to 60 degrees c. for 30 minutes and is destroyed by boiling (100 degrees c). filtration through a berkefeld filter does not diminish the nutrient value of the serum. 3. the cultural value of different animal sera varies considerably. it is entirely absent from the sera of the rat and the pig. the sera of the rabbit ... | 1918 | 19868228 |
| the survival of leptospira (spirochaeta) icterohaemorrhagiae in nature; observations concerning microchemical reactions and intermediary hosts. | 1. leptospira icterohaemorrhagiae is unable to grow in the urine, either with or without the addition of suitable culture ingredients, the acidity of the urine being detrimental to the growth. it survives less than 24 hours, unless the urine is neutralized or slightly alkalized, when the period of survival is somewhat longer. if suitable nutrient ingredients are added to the neutralized or slightly alkalized urine, the organism is able to grow for about 10 days, after which multiplication ceases ... | 1918 | 19868229 |
| spirochaeta hebdomadis, the causative agent of seven day fever (nanukayami) : first paper. | a new species of spirochete which we have called spirochaeta hebdomadis has been described as the specific etiological agent of seven day fever, a disease prevailing in the autumn in fukuoka and other parts of japan. this spirochete is distinguishable from spirochaeta icterohaemorrhagiae to which it presents certain similarities. young guinea pigs are susceptible to inoculation with the blood of patients and to pure cultures of the spirochete, and those developing infection exhibit definite symp ... | 1918 | 19868269 |
| spirochaeta hebdomadis, the causative agent of seven day fever (nanukayami) : second paper. | 1. spirochata hebdomadis is always present in seven day fever and can be confirmed by animal experiments with guinea pigs of light weight. 2. the causative agent of this disease can also be found in film preparations of the blood of patients, though it is not present in large numbers. 3. spirochaeta hebdomadis is discharged in the urine of patients having seven day fever. the number of spirochetes in the urine is great during convalescence. 4. seven day fever is a disease found not only in the p ... | 1919 | 19868314 |
| the cultivation of spirochaeta icterohaemorrhagiae and the production of a therapeutic anti-spirochaetal serum. | 1919 | 20474680 | |
| the cultivation and biological characteristics of spirochaeta obermeieri (recurrentis). | a study of the growth requirements of spirochoeta obermeieri resulted in the perfection of a method which enabled us (1) to cultivate the organisms consistently from the blood of infected mice and rats, (2) to maintain the viability of cultures for periods of at least 3 to 7 weeks, and (3) to carry them on in successive subcultures by transplanting at intervals of 2 to 4 weeks. this method is essentially the same as the noguchi technique for the cultivation of the leptospira group, but emphasize ... | 1922 | 19868607 |
| spirochaeta eurygyrata : a note on its life history and cultivation. | 1. pure lines of spirochoeta eurygyrata were isolated and cultured. 2. they lived longest in a medium which was made up of sodium chloride and pig serum water. 3. they stained readily with iron-hematoxylin, giemsa's stain, cross' stain, and carbolfuchsin. 4. they did not stain with the vital dyes used. 5. they divide by transverse division. 6. transverse bars, which are seen in stained spirochetes and in dead ones with dark-field illumination, are considered coagulated protoplasm, due to death. ... | 1922 | 19868697 |
| a case of rat-bite fever in england: recovery of the spirochaete from the blood. | 1924 | 20771458 | |
| experiments on the production of wassermann reagins by means of trypanosomes. | since it is known that positive wassermann reactions prevail in trypanosomiasis of rabbits, similar to those in syphilis, trypanosomes were used for an inquiry into the cause of this reaction. injections with dead trypanosomes into rabbits proved that these microbes are highly active antigens and suffice in themselves to produce strongly positive wassermann sera, in analogy to the findings reported by f. klopstock with spirochaeta pallida. although a number of questions require further study, ye ... | 1927 | 19869266 |
| the pathogenesis of rheumatic fever in its climatological relationship to a possible insect carrier. | a short while ago a special sub-committee of the british medical association [1] sat to inquire into the problem of rheumatic heart disease in children, and suggested, among other conclusions, that the material for any accurate world map of the incidence of rheumatism was probably not available. my objects in presenting this paper are:-(1) to provide data for this map.(2) to show that the geographical distribution of rheumatic fever coincides with that of the common rat flea, ceratophyllus fasci ... | 1928 | 19986438 |
| syphilology: viability of spirochaeta pallida. | 1928 | 18740847 | |
| filtration experiments with spirochaeta schaudinnii. | 1934 | 20475245 | |
| the role of the spirochaete in the wassermann reaction. | 1939 | 20475495 | |
| [on the possibility of the transmission by lice of the spirochetes of tick recurrent fever spirochaeta uzbekistanica (sp. sogdianum)]. | 1945 | 20280628 | |
| the effect of low temperature on the spirochetes of relapsing fever. | 1945 | 21005566 | |
| the effect of low temperature on the spirochetes of relapsing fever; the structure and motility of spirochaeta novyi. | 1945 | 21005567 | |
| the structure of spirochaeta novyi as revealed by the electron microscope. | 1945 | 21011725 | |
| the effect of low temperature on the spirochetes of relapsing fever; the viability of four strains of spirochetes stored at -48 degrees centigrade. | 1945 | 21065380 | |
| the effect of low temperature on the spirochetes of relapsing fever: ii. the structure and motility of spirochaeta novyi. | 1945 | 16561004 | |
| the structure of spirochaeta novyi as revealed by the electron microscope. | 1945 | 16561047 | |
| therapeutic action of different penicillins on spirochaeta recurrentis infections in mice. | 1946 | 20984765 | |
| the structure of spirochaeta novyi as revealed by the electron microscope. | 1946 | 20987023 | |
| isolation of virulent treponema pallidum from human aorta thirty-two hours after death from cardiovascular syphilis. | 1946 | 20996102 | |
| [on isolation of cultures of spirochaeta pallida from syphilitic patients]. | 1946 | 20279621 | |
| the problem of reinoculation of human beings with spirochaeta pallida; a review of the literature. | 1946 | 21018654 | |
| [not available]. | 1946 | 20293718 | |
| the problem of identification of oral spirochetes and description of a precipitin test for their serological differentiation. | 1946 | 20280884 | |
| silver impregnation of spirochetes in tissue sections; description of a new technic. | 1946 | 20282141 | |
| the relative importance of the renal and hepatic lesions in experimental leptospirosis icterohaemorrhagica. | 1946 | 20283070 | |
| a note on two blood parasites of cattle (spirochaeta theileri and bartonella bovis) recorded for the first time in australia. | 1946 | 20290808 | |
| [purification of leptospira strains in vivo]. | 1946 | 20277164 | |
| [liberation of leptospira strains from spontaneous agglutination]. | 1946 | 20277165 | |
| [viability of leptospira on food materials]. | 1946 | 20277166 | |
| acquired resistance of treponema pallidum to penicillin. | 1946 | 20277710 | |
| agglutination of leptospirae. | 1947 | 20278699 | |
| prolonged storage of human pathogenic protozoa with conservation of virulence; observations on the storage of helminths and leptospiras. | 1947 | 20279331 | |
| henry, the spirochaete, and the ladies. | 1947 | 20243250 | |
| a new quick method for staining treponema pallidum. | 1947 | 20244557 | |
| polymorphism in treponema recurrentis and spirochaeta vincenti. | 1947 | 20249283 | |
| the minimal infectious inoculum of s. pallida in rabbits, and its rate of multiplication in vivo. | 1947 | 20249674 | |
| [not available]. | 1947 | 20253294 | |
| [not available]. | 1947 | 20253525 | |
| [not available]. | 1947 | 20253536 | |
| bacteriologic investigations of the oral spirochetal flora in ulcerative stomatitis (vincent's infection). | 1947 | 20260856 | |
| [not available]. | 1947 | 20268209 | |
| [not available]. | 1947 | 20270416 | |
| [not available]. | 1947 | 20270417 | |
| [not available]. | 1947 | 20270430 | |
| [not available]. | 1947 | 20270431 | |
| a new blood spirochaete in the grivet monkey; ceropithecus aethiops. | 1947 | 20291370 | |
| agglutination studies of the smaller oral treponemes, borrelia vincenti and cultured strains of treponema pallidum. | 1947 | 20292512 | |
| preservation of borrelia vincenti and cultured strains of treponema pallidum by the lyophil process. | 1947 | 20285099 | |
| [not available]. | 1947 | 20296900 | |
| isolation of an unidentified spirochete from hen's eggs after inoculation with liver tissue from hens. | 1947 | 20341597 | |
| loss of virulence of treponema pallidum during processing of dried blood serum. | 1947 | 20344588 | |
| [not available]. | 1947 | 18880880 | |
| [not available]. | 1947 | 18896624 | |
| [not available]. | 1947 | 18898327 | |
| [not available]. | 1947 | 18911483 | |
| [not available]. | 1947 | 18918718 | |
| [not available]. | 1947 | 18921701 | |
| viability of treponema pallidum. | 1947 | 18935610 |