Publications

epidemiology of viral infections in singapore.	as singapore is a densely populated island, and also a major air and sea port, the importation and dissemination of viral infections is facilitated. respiratory viral infections have the highest prevalence rates, influenza and respiratory syncytial virus (rsv) being the most important ones. seasonal variation occurs with influenza, rsv and parainfluenza virus type 1 infections. the age distribution and clinical picture associated with infections due to the various respiratory viruses are similar ...	1987	2825585
clinical characteristics of an outbreak of hand, foot and mouth disease in singapore.	we experienced a hand, foot and mouth disease (hfmd) outbreak in late year 2000 in singapore. between 14 september 2000 and 14 november 2000, a total of 3526 cases of hfmd were notified. there were 652 patients clinically suspected to have hfmd, who were seen at the children's emergency department of kk women's and children's hospital of singapore.	2003	12854382
epidemiology and control of hand, foot and mouth disease in singapore, 2001-2007.	we reviewed the epidemiology of hand, foot and mouth disease (hfmd) in singapore after the 2000 epidemic caused by enterovirus 71 (ev71), with particular reference to the cyclical pattern, predominant circulating enteroviruses and impact of prevention and control measures in preschool centres.	2009	19271036
seroepidemiology of coxsackievirus a6, coxsackievirus a16, and enterovirus 71 infections among children and adolescents in singapore, 2008-2010.	coxsackieviruses a6 (cv-a6) and a16 (cv-a16) and enterovirus 71 (ev-a71) have caused periodic epidemics of hand, foot and mouth disease (hfmd) among children in singapore. we conducted a cross-sectional study to estimate the seroprevalence of these enteroviruses among singapore children and adolescents. the study was conducted between august 2008 and july 2010. it involved 700 singapore residents aged 1-17 years whose residual sera were obtained following the completion of routine biochemical in ...	2015	26011735
basic reproduction number of coxsackievirus type a6 and a16 and enterovirus 71: estimates from outbreaks of hand, foot and mouth disease in singapore, a tropical city-state.	coxsackievirus a6 (cv-a6), coxsackievirus a16 (cv-a16) and enterovirus 71 (ev-a71) were the major enteroviruses causing nationwide hand, foot and mouth disease (hfmd) epidemics in singapore in the last decade. we estimated the basic reproduction number (r 0) of these enteroviruses to obtain a better understanding of their transmission dynamics. we merged records of cases from hfmd outbreaks reported between 2007 and 2012 with laboratory results from virological surveillance. r 0 was estimated ba ...	2016	26374168