Publications

structures and cytotoxic evaluation of new and known acyclic ene-ynes from an american samoa petrosia sp. sponge.	four new compounds, (-)-petrosynoic acids a-d (1-4), and five known congeners, pellynols a (5), c (6), d (7), f (8), and i (9), were isolated from a petrosia sp. marine sponge collected in american samoa. isolation work was guided by cytotoxicity against human lung cancer cells (h460). the structures of the c31-c33 polyacetylenes (1-9) were determined on the basis of 1d- and 2d-nmr analysis, mass spectrometry, and comparison of specific rotation values. compounds 1-9 were found to be broadly cyt ...	2013	23368996
comparative population assessments of nautilus sp. in the philippines, australia, fiji, and american samoa using baited remote underwater video systems.	the extant species of nautilus and allonautilus (cephalopoda) inhabit fore-reef slope environments across a large geographic area of the tropical western pacific and eastern indian oceans. while many aspects of their biology and behavior are now well-documented, uncertainties concerning their current populations and ecological role in the deeper, fore-reef slope environments remain. given the historical to current day presence of nautilus fisheries at various locales across the pacific and india ...	2014	24956107
<i>cinachyrella anatriaenilla</i> sp. nov., a new tetillid sponge with microacanthoxeas from american samoa in the south pacific.	several sponges from american samoa, collected by the coral reef research foundation, republic of palau, were tentatively identified by one of us as acanthotetilla cf seychellensis (thomas 1973), due to the possession of relatively small acanthose oxeas, compared to those of other species of the genus acanthotetilla burton 1959. these sponges were later compared to cinachyrella australiensis (carter 1886), taking into account the lack of conspicuous spination on the acanthose oxeas and general f ...	2017	28609936
integrating molecular networking and biological assays to target the isolation of a cytotoxic cyclic octapeptide, samoamide a, from an american samoan marine cyanobacterium.	integrating lc-ms/ms molecular networking and bioassay-guided fractionation enabled the targeted isolation of a new and bioactive cyclic octapeptide, samoamide a (1), from a sample of cf. symploca sp. collected in american samoa. the structure of 1 was established by detailed 1d and 2d nmr experiments, hresims data, and chemical degradation/chromatographic (e.g., marfey's analysis) studies. pure compound 1 was shown to have in vitro cytotoxic activity against several human cancer cell lines in b ...	2017	28055219