Publications

mycoses, bacterial infections and antibacterial activity in sandflies (psychodidae) and their possible role in the transmission of leishmaniasis.	high incidence of mycoses were found in the guts and malpighian tubes of phlebotomus papatasi from the jordan valley and p. tobbi from zakinthos, greece. infections with several different bacteria were also found in the guts of female p. tobbi. fungi cultured from guts of laboratory reared p. papatasi that had similar mycoses were identified as aspergillus sclerotiorum and saccharomyces cerevisiae. fungi-infected laboratory reared p. papatasi were refractory to artificial infections with a leish ...	1985	3982854
cutaneous leishmaniasis in jordan: biochemical identification of human and psammomys obesus isolates as leishmania major.	as part of a series of epidemiological and ecological studies of leishmaniasis in jordan, we have made functional studies of four isolates from human lesions and from ear lesions of three field-collected psammomys obesus. primary isolates were subcultured, frozen stabilates prepared and balb/c mouse infectivity experiments initiated. each mouse was inoculated with 4-8 x 10(4) promastigotes into a hind footpad. quantitative evaluation of the footpads showed enlargement three to four weeks postino ...	1988	3041929
leishmanin skin test survey in a focus of high endemicity of leishmania major in jordan.		1993	8103629
serodiagnosis of cutaneous leishmaniasis in jordan using indirect fluorescent antibody test and the enzyme-linked immunosorbent assay.	the usefulness of ifat and elisa, in the detection of antibodies to cutaneous leishmaniasis (cl) in jordanian cases was studied. serum samples were collected from three groups of confirmed or putative cl patients (n = 100), 132 healthy blood donors, 10 patients with pulmonary tuberculosis (tb), and 16 patients with typhoid fever (tf). antigens for both tests were prepared from promastigotes of a leishmania major isolate. at a serum dilution of respectively 1:16 and 1:100 both ifat and elisa had ...	1995	7676907
incrimination of phlebotomus papatasi as vector of leishmania major in the southern jordan valley.	the status of sandflies as vectors of cutaneous leishmaniasis in the southern jordan valley was investigated during 1992. sandflies were collected from domestic habitats and from burrows of psammomys obesus. of 686 phlebotomus papatasi females collected from burrows, fourteen harboured promastigotes in their guts. on the other hand, none of 1446 p.papatasi females collected from domestic habitats were found infected. the highest infection rate (5.5%) was recorded in november at the end of the sa ...	1995	8541595
two recent but temporally distinct outbreaks of cutaneous leishmaniasis among foreign workers in the dead-sea area of jordan.	two temporally distinct outbreaks of human cutaneous leishmaniasis (cl), as well as scattered cases of the disease, have recently been observed close to the dead sea, in jordan. each of the two outbreaks, which occurred in 2004/2005 and 2007/2008, involved a group of foreign workers who were deployed within otherwise uninhabited locations. during each outbreak, about 20% of the workers were found infected with the causative parasite. in the earlier outbreak, 61 workers were found to have skin le ...	2009	19583910
profiling of human acquired immunity against the salivary proteins of phlebotomus papatasi reveals clusters of differential immunoreactivity.	phlebotomus papatasi sand flies are among the primary vectors of leishmania major parasites from morocco to the indian subcontinent and from southern europe to central and eastern africa. antibody-based immunity to sand fly salivary gland proteins in human populations remains a complex contextual problem that is not yet fully understood. we profiled the immunoreactivities of plasma antibodies to sand fly salivary gland sonicates (sgss) from 229 human blood donors residing in different regions of ...	2014	24615125
the jordanian mid jordan valley is a classic focus of leishmania major as revealed by rflp of 56 isolates and 173 its-1-pcr-positive clinical samples.	the identity of the causative species of cutaneous leishmaniasis (cl) in the endemic jordanian mid jordan valley (jmidjv) was investigated using the polymerase chain reaction (pcr) amplifying the ribosomal internal transcribed spacer 1 (its-1) followed by the restriction fragment length polymorphism (rflp). the geographical distribution of cl and the usefulness of its1 pcr in diagnosis of suspected cl in the study area were also addressed. over the period from 2004 to 2009, 56 clinical isolates ...	2015	25450773
molecular diagnosis and identification of leishmania species in jordan from saved dry samples.	diagnosis of the endemic cutaneous leishmaniasis (cl) in jordan relies on patient clinical presentation and microscopic identification. studies toward improved identification of the causative leishmania species, especially in regions where multiple species exist, and the introduction of these techniques into medical diagnosis is paramount. this study looked at the current epidemiology of cl in jordan. clinically diagnosed 41 patients with cl were tested for the presence of leishmania parasite us ...	2016	27403435