Publications

the rise and fall of k65r in a portuguese hiv-1 drug resistance database, despite continuously increasing use of tenofovir.	the overall prevalence of the k65r mutation in hiv-1 reverse transcriptase has increased in treatment-experienced patients, mostly attributed to the increasing use of tenofovir (tdf). a number of tdf-based regimens are associated with high rate of early virological failure. in this study, we evaluated the impact of these combinations on k65r selection over time.	2009	19038365
discordant genotypic interpretation and phenotypic role of protease mutations in hiv-1 subtypes b and g.	hiv-1 group m is classified into nine different subtypes. most antiretroviral (arv) drugs have been developed for subtype b, and the response of non-b subtypes in terms of susceptibility and the acquisition of drug resistance when facing those drugs is largely unknown. in this study, we aimed to address differences in the impact of protease inhibitor (pi)-selected mutations on subtypes b and g.	2009	19136678