Publications

canines as sentinel species for assessing chronic exposures to air pollutants: part 2. cardiac pathology.	the principal objective of this study is to evaluate by light and electron microscopy (lm, em) the heart tissues in stray southwest and northeast metropolitan mexico city (swmmc, nemmc) dogs and compare their findings to those from 3 less polluted cities (cuernavaca, tlaxcala, and tuxpam). clinically healthy mongrel dogs, including 109 from highly polluted swmmc and nemmc, and 43 dogs from less polluted cities were studied. dogs residing in cities with lower levels of pollutants showed little or ...	2001	11353144
air pollution and brain damage.	exposure to complex mixtures of air pollutants produces inflammation in the upper and lower respiratory tract. because the nasal cavity is a common portal of entry, respiratory and olfactory epithelia are vulnerable targets for toxicological damage. this study has evaluated, by light and electron microscopy and immunohistochemical expression of nuclear factor-kappa beta (nf-kappab) and inducible nitric oxide synthase (inos), the olfactory and respiratory nasal mucosae, olfactory bulb, and cortic ...	2002	12051555
dna damage in nasal and brain tissues of canines exposed to air pollutants is associated with evidence of chronic brain inflammation and neurodegeneration.	acute, subchronic, or chronic exposures to particulate matter (pm) and pollutant gases affect people in urban areas and those exposed to fires, disasters, and wars. respiratory tract inflammation, production of mediators of inflammation capable of reaching the brain, systemic circulation of pm, and disruption of the nasal respiratory and olfactory barriers are likely in these populations. dna damage is crucial in aging and in age-associated diseases such as alzheimer's disease. we evaluated apur ...	2003	14692621