Publications

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epidemiological studies on cystic echinococcosis in china--a review.in the four decades from 1951 to 1990, the six provinces or autonomous regions (xinjiang, gansu, qinghai, ningxia, xizang and nei monggol) reported a total of 26,065 surgical cases of hydatid disease, most of which were reported in the recent decade. about one third of the patients was children and adolescents under 15 years old. so far, cystic hydatid infections of local origin have been confirmed in 22 provinces, autonomous regions and municipalities in the whole nation. findings of x-ray exam ...19957546341
epidemiology of alveolar echinococcosis with particular reference to china and europe.human alveolar echinococcosis (ae), caused by the metacestode of the fox tapeworm echinococcus multilocularis, is the most pathogenic zoonosis in temperate and arctic regions of the northern hemisphere. prospective collection of human cases in some areas and mass screenings using ultrasound imaging and confirmation with serological techniques have markedly improved our knowledge of the epidemiology of the disease in humans during the past two decades. transmission occurs when eggs of the tapewor ...200315027607
echinococcosis on the tibetan plateau: prevalence and risk factors for cystic and alveolar echinococcosis in tibetan populations in qinghai province, china.infections by larval stages of tapeworms of the genus echinococcus (echinococcosis or hydatid disease) are zoonotic infections of major public health importance throughout much of the world. humans become infected through accidental ingestion of eggs passed in faeces of canid definitive hosts. tibetan populations of china have some of the highest documented levels of infections by both echinococcus granulosus and e. multilocularis, the causes of cystic and alveolar echinococcosis, respectively. ...200315027608
[study on an epidemic of human lung plaque in nangqian county, qinghai province].to study an epidemic of human lung plague fulminant from september to october, 2004 in nangqian county, qinghai province.200516471218
dual infection of animal hosts with different echinococcus species in the eastern qinghai-tibet plateau region of china.the eastern qinghai-tibet plateau of china is a highly endemic region of echinococcosis where echinococcus granulosus sensu stricto (sheep strain), echinococcus multilocularis, and echinococcus shiquicus are distributed sympatrically. we developed a polymerase chain reaction-based restriction fragment length polymorphism (pcr-rflp) method for the identification of the three species in this region. the pcr-rflp showed the dual infection of animals with different echinococcus spp. the first case w ...200616896135
impact of overgrazing on the transmission of echinococcus multilocularis in tibetan pastoral communities of sichuan province, china.overgrazing was assumed to increase the population density of small mammals that are the intermediate hosts of echinococcus multilocularis, the pathogen of alveolar echinococcosis in the qinghai tibet plateau. this research tested the hypothesis that overgrazing might promote echinococcus multilocularis transmission through increasing populations of small mammal, intermediate hosts in tibetan pastoral communities.200717355829
[epidemiological survey on echinococcus infection in animals in qinghai province].parasitological and dissection methods were used to confirm echinococcus infection and echinococcosis in animals, and to understand the epidemiological situation in final and intermediate animal hosts in qinghai province. three echinococcus species were found in the province including e. granulosus, e. multilocularis and e. shiquicus. the prevalence of hydatid disease showed a tendency of increase with an average rate of over 50% in yaks and sheep. higher prevalence in wild animals as intermedia ...200718038811
[an epidemiological survey on echinococcosis in zhiduo county of qinghai province].the survey was carried out in july, 2006 in zhiduo county. the iha and elisa positive rate in human population was 4.5% (42/933) and 8.2% (76/931) respectively. ultrasonography revealed a morbidity of 3.4% (33/979) with 3.2% echinococcus granulosus and 0.2% of e. multilocularis respectively. animal dissection showed an infection rate of 15.1% (14/93) in pikas with one infected by e. shiquicus proved by molecular biology. coproantigen rate by elisa was 62% (12/193) in dogs and 35.7% (5/14) in wol ...200718038785
species identification of human echinococcosis using histopathology and genotyping in northwestern china.human cystic echinococcosis, caused by infection with the larval stage of echinococcus granulosus, and alveolar echinococcosis, caused by the larval form of e. multilocularis, are known to be important public health problems in western china. echinococcus shiquicus is a new species of echinococcus recently described in wildlife hosts from the eastern tibetan plateau and its infectivity and/or pathogenicity in humans remain unknown. in the current study, parasite tissues from various organs were ...200818396303
seroepidemiology of neospora caninum and toxoplasma gondii infection in yaks (bos grunniens) in qinghai, china.neospora caninum is a protozoan parasite and is closely related to toxoplasma gondii, but they are antigenically different. n. caninum and t. gondii infection in a variety of animals such as cattle, dogs, and cats has been reported, but there is little information on the infection of these parasites in domestic yaks. seroprevalence of antibodies to t. gondii and n. caninum in yaks (bos grunniens) from eight regions of qinghai, china were investigated by the indirect agglutination test (iat) and ...200818242860
cystic and alveolar echinococcosis: an epidemiological survey in a tibetan population in southeast qinghai, china.an epidemiological investigation on echinococcosis was made in jiuzhi county of qinghai province, western china. ultrasonography and an indirect hemagglutination test revealed a morbidity of 8.0% (124/1,549) and a seroprevalence of 25.8% (287/1,113), respectively, in the tibetan population. the morbidity in herdsmen (16.6%) and buddhist priests (15%) was significantly higher than that in other occupation groups (3.2%), and it was higher in females (9.8%) than in males (6.2%). the ultrasound imag ...200818503183
[epidemiological survey on echinococcosis in darlag county of qinghai province].to make an epidemiological investigation on echinococcosis in darlag county, guoluo tibetan autonomous prefecture of qinghai province.200919459494
[the risk evaluation and response to the spread of hydatid disease after yushu earthquake in qinghai province].yushu of qinghai province is the mixed endemic area for cystic and alveolar hydatid diseases. reviewing the previous data on the prevalence of the disease and the information from the communicable disease surveillance network during 2004 to april 15, 2010, possible impact of the yushu earthquake was evaluated. it revealed that post-earthquake conditions might bring about risk factors for an increase of disease transmission, which included more deaths of livestock, increase of the number of stray ...201021137323
[effect of control pattern with emphasis on canine deworming in a pilot of echinococcosis in highly endemic area, southern qinghai plateau].to evaluate the effect of control pattern with an emphasis on canine deworming in a pilot of echinococcosis in highly endemic area of southern qinghai plateau.201121972606
a dog-associated primary pneumonic plague in qinghai province, china.primary pneumonic plague (ppp) caused by yersinia pestis is the most threatening clinical form of plague. an outbreak was reported in july 2009 in qinghai province, china.201121288842
serological survey of toxoplasma gondii in tibetan mastiffs (canis lupus familiaris) and yaks (bos grunniens) in qinghai, china.toxoplasma gondii is an amphixenosis which has extensive hosts. in recent years, the prevalence of t. gondii in china has been reported, while little is known on the survey of t. gondii infection in northwest china, especially in yaks (bos grunniens) and tibetan mastiffs (canis lupus familiaris). the current study survey the infection of t. gondii in tibetan mastiffs and yaks in qinghai province, china.201222330277
canis lupus familiaris involved in the transmission of pathogenic yersinia spp. in china.to investigate canines carrying pathogens associated with human illness, we studied their roles in transmitting and maintaining pathogenic yersinia spp. we examined different ecological landscapes in china for the distribution of pathogenic yersinia spp. in canis lupus familiaris, the domestic dog. the highest number of pathogenic yersinia enterocolitica was shown from the tonsils (6.30%), followed by rectal swabs (3.63%) and feces (1.23%). strains isolated from plague free areas for c. lupus fa ...201424861841
the complete mitochondrial genome of hequ tibetan mastiff canis lupus familiaris (carnivora: canidae).the hequ tibetan mastiff canis lupus familiaris (carnivora: canidae) is a primitive breed of large dogs native to the northeastern qinghai-tibetan plateau of china. in this study, its complete mitochondrial genome sequence has been assembled and characterized using high-throughput illumina sequencing technology. the circular genome is 16 730 bp in length, and possesses all genomic components as typically found in most other metazoan mitogenomes. the gene arrangement is identical to those of most ...201626709544
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