Publications

leptospira bangkok, a new serotype of the australis group isolated from a dog.		1965	14317221
the incidence of canine leptospirosis in bangkok.		1965	14319649
seasonal incidence of canine leptospirosis in bangkok.		1966	5950686
rabid dogs in bangkok--thonburi. a preliminary study.		1972	4563991
changes in the anterior nasal spine and the alveolar process of the macillae in leprosy a clinical examination.	a brief review is presented of the danish medieval skeletons with leprosy changes, particularly in the skulls, where the pathologic specific changes found are termed facies leprosa. the clinical aspect of facies leprosa is termed bergen syndrome i (nasal leprosy) and bergen syndrome ii (the leprogenic changes of the alveolar process of the maxilla superior with loosening and/or loss of the frontal incisors). an account is given of the interim result of a clinical examination of 333 inpatients at ...	1974	4617722
rabies: a study at siriraj hospital, bangkok.		1978	564934
[intestinal helminths in bangkok stray dogs and their role in public health (author's tranls)].	feces examination of 107 stray dogs in bangkok, thailand, on intestinal helminths showed the following rates: hookworms 100%, trichuris vulpis 54.2%, toxocara canis 6.5%, gnathostoma spinigerum 2.8%, spirocerca lupi 17.8%, diphyllobothrium mansoni 1.9%, and opisthorchis viverrini 1.9%. out of these species hockworms (especially a. braziliense), t. canis, g. spinigerum, and d. mansoni are important sources of human cutaneous or visceral larva migrans, the latter two being special parasites of the ...	1980	7435002
epidemiology of human rabies post-exposure prophylaxis in bangkok, 1984-1986.	a study was conducted to determine the current situation of human rabies post-exposure prophylaxis (pep) in bangkok for the period 1984-1986. a review of all bangkok residents receiving pep at the queen saovabha memorial institute revealed an increasing incidence rate of pep from 10.1 cases per 10,000 persons in 1984 to 12.6 cases per 10,000 persons in 1986. the highest incidence rate was observed in young males aged 5-14 years. about 68% of individuals receiving pep had exposures to bites, espe ...	1988	3238466
epidemiology and characterization of leptospirosis at an urban and provincial site in thailand.	patients with fuos at the children's hospital in bangkok and the chao phya abhai bhu bejhr hospital in prachinburi were screened for leptospirosis by blood and urine culture in addition to microagglutination testing of their serum. animal populations in urban and periurban areas of bangkok were surveyed for evidence of leptospira infection. three rural sites near the prachinburi provincial hospital were also surveyed. the rodents' and domestic animals' blood, urine, and/or kidney cell samples we ...	1988	3227409
failure of rabies postexposure treatment in thailand.	three failures of postexposure rabies treatment using imported purified duck embryo cell and vero cell rabies vaccines are reported from thailand. reference is made to eight additional previously reported thai patients, six of whom had received human diploid cell vaccine. an analysis of these cases reveals that there were serious flaws in management in all of these patients. it is stressed that 45% of human rabies deaths in thailand occur within 20 days of being bitten and 71% are dead within 28 ...	1989	2718606
dog-bite injuries at a bangkok teaching hospital.	thailand has a large domestic and stray dog population and buddhist cultural beliefs encourage feeding and protection of stray animals. dog bites are common injuries encountered in emergency rooms throughout the country. a prospective study of such bites seen at a teaching hospital in bangkok revealed that: (1) dog bites represent 5.3% of injuries seen in the emergency room; (2) the majority occur on the street, are inflicated by stray dogs and are interpreted by the victim as unprovoked. childr ...	1993	8147281
antigenic analysis of influenza viruses isolated in thailand between 1991 and 1994.	we studied the epidemiology of influenza viruses in thailand by isolating them and comparing their antigenic features with those of japanese isolates. between 1991 and 1994, 32 strains were isolated from 186 throat swab specimens. twenty-one of the 32 isolates were of type a, subtype h3n2, and 11 strains were type b. it was suggested that the isolates of type a, subtype h3n2, drifted antigenically from a/beijing/352/89-like to a/kitakyusyu/159/93-like variants used as reference strains for compa ...	1997	9258939
toxocara and gnathostoma among stray canines in bangkok.	stomachs and intestines of 88 adult and 112 young stray dogs were obtained from the rabies control subdivision, bangkok, and examined especially for the presence of gnathostoma spinigerum and toxocara canis. forty-five dogs were found positive for t. canis (overall prevalence 22.5%) but none were found infected with g. spinigerum. the prevalence of t. canis in young dogs was 37.5% (42 of 112) whereas in adult dogs was only 3.4% (3 of 88). the total number of t. canis recovered from the 45 positi ...	1998	10772557
a study of human rabies immune globulin manufactured by the thai red cross.	this is a prospective post marketing study of 4496 patients presenting with severe animal bites in a canine rabies endemic region. they received human rabies immune globulin manufactured from volunteer blood donors at the national blood center of the thai red cross society at bangkok. all patients also received a full course of tissue culture rabies vaccine. only three subjects reported an adverse reaction (redness and itching at the immune globulin injection sites). none of the patients died du ...	1999	10067706
dog-bite injuries at the animal bite clinic of the thai red cross society in bangkok.	canine rabies remains a public health problem in thailand and other developing countries. this study of animal bites at the animal bite clinic at the queen saovabha memorial institute revealed that: (1) the majority of patients were bitten by dogs and the time of the attack was mostly during the day. (2) school-aged children are at the highest risk for animal bites. (3) the most common site of injury are the legs and foot (64.2%), with the second most common site being the hands and fingers (21. ...	2000	11253884
risk of rabies after mammal bites in thai children.	the data were collected by questionnaire at the outpatient department of chulalongkorn university hospital, bangkok thailand. this study revealed that 52 per cent of children had pet mammals in their home of which 67 per cent were dogs. 23.6 per cent of these children gave at least one history of a mammal bite inside (53.4%) or outside (46.6%) their house. mammal bites of children could be found at all ages. however, most were in the age group of 10-14 years (42.3%), and 5-9 years (39.7%). the m ...	2002	12075725
dog rabies in bangkok.	canine rabies remains a serious public health problem in thailand. the queen saovabha memorial institute (qsmi) of the thai red cross society is the principal rabies diagnostic center in central thailand. the retrospective study of canine rabies cases collected between 1994-1999 revealed that: (1) the prevalence of rabid dogs has decreased, and was associated with an overall decrease in the number of animals submitted for examination. however, the percentages of dogs with positive fluorescent an ...	2002	12075724
prevalence of rabies virus and hantaan virus infections in commensal rodents and shrews trapped in bangkok.	five hundred rodents and shrews (rattus norvegicus: 458, rattus rattus: 28, rattus exulans: 5, mus musculus: 4 and suncus murine: 5) trapped from the fresh food markets around bangkok area were investigated for rabies virus and hantaan virus infections. no rabies viral antigens in the animals' brains were detected by direct immunofluorescence. on the other hand, antibodies to hantaan virus were demonstrated in the sera of 7 (1.53%) r. norvegicus caught in various markets using a particle aggluti ...	2003	14696782
the frequency rate of toxocara species contamination in soil samples from public yards in a urban area "payathai", bangkok, thailand.	toxocara species are most common roundworms of canidae and felidae. human toxocariasis develops by ingesting of embryonated eggs in contaminated soil. there is no previous report of toxocara contamination in the soil samples from the public areas in bangkok. for this reason our study have been carried out to examine the frequency of toxocara eggs in public yards in bangkok, thailand. a total of 175 sand and clay samples were collected and examined for parasite eggs. according to this study, toxo ...	2004	15141284
genetic typing of feline rabies virus isolated in greater bangkok, thailand.	to study the molecular epidemiology of rabies virus that is prevalent among cats in greater bangkok, thailand, a total of 17 rabies virus isolates from cats were characterized and compared with 120 rabies virus isolates from dogs. analyses were performed on the genetic polymorphism in the rabies virus nucleoprotein (n) gene. rabies virus n gene of isolates was amplified by reverse transcriptionpolymerase chain reaction. the diversity of n gene was revealed by the restriction fragment length poly ...	2004	15107541
transmission dynamics of rabies virus in thailand: implications for disease control.	in thailand, rabies remains a neglected disease with authorities continuing to rely on human death statistics while ignoring the financial burden resulting from an enormous increase in post-exposure prophylaxis. past attempts to conduct a mass dog vaccination and sterilization program have been limited to bangkok city and have not been successful. we have used molecular epidemiology to define geographic localization of rabies virus phylogroups and their pattern of spread in thailand.	2005	15985183
rabies and dog population control in thailand: success or failure?	despite a success in reducing rabies deaths from almost 200 to less than 20 annually, this may not be considered a success. more than 400,000 persons required rabies post-exposure prophylaxis (pep) in 2003, more than 4 times as many as those in 1991 [93,641 cases in 1991; 183,815 in 1996 and 350,535 in 2001]. the number of samples submitted for testing in rabies diagnostic laboratories has been declining. however, the percent of samples that were confirmed infected with rabies during the 10 year ...	2005	15960231
laboratory diagnosis of rabies in bangkok and the central part of thailand, 2001-2004.		2005	15962684
genetic analysis of dog rabies viruses circulating in bangkok.	the genetic diversity of the rabies virus glycoprotein (g) gene isolated from individual rabid dogs (inter-hosts) and within a single infected dog (intra-host) has been analyzed in an effort to better understand selective pressures and population shifts among rabies viruses circulating in bangkok. comparison of individual master sequences among inter-hosts revealed that the dog virus isolates circulating in bangkok were phylogenetically closely related. the ectodomain of the glycoprotein was hig ...	2006	16061424
complex genetic structure of the rabies virus in bangkok and its surrounding provinces, thailand: implications for canine rabies control.	dog vaccination and population management have been suggested as priorities in attempts at disease control in canine rabies-endemic countries. budget limitations and the complexity of social, cultural and religious variables have complicated progress in the developing world. in bangkok, thailand, an intensive canine vaccination and sterilization programme has been in place since november 2002. our objective was to determine if the rabies virus could be mapped according to its genetic variations ...	2006	16352324
detection of hepatozoon canis in stray dogs and cats in bangkok, thailand.	a rapidly increasing stray animal population in bangkok has caused concern regarding transmission of vector-borne and zoonotic diseases. the purpose of this study was to determine if stray animals in bangkok are a potential reservoir of hepatozoon, a genus of tick-borne parasites that has received little attention in thailand. blood samples were collected from stray companion animals near monasteries in 42 bangkok metropolitan districts. both dogs and cats were sampled from 26 districts, dogs al ...	2006	17135555
a retrospective study of the clinical hematology and the serum biochemistry tests made on canine dirofilariasis cases in an animal hospital population in bangkok, thailand.	heartworm disease, caused by the filarial nematode, dirofilaria immitis, is a major, potentially life-threatening disease of dogs, with worldwide distribution and global significance. it is not only of veterinary importance but it also has zoonotic potential in many regions. it is considered as an endemic disease in thailand, although clinical data about the disease is rarely reported. the objectives of this study were to characterize the clinical hematology and the biochemistry of canine dirofi ...	2007	17095027
seroprevalence of leptospirosis in domesticated asian elephants (elephas maximus) in north and west thailand in 2004.	serum samples from asian elephants (elephas maximus) in the kanchanaburi, chiang mai and lampang provinces of thailand were tested using the microscopic agglutination test against 22 serovars of leptospira interrogans. a titre of more than 1:100 was used as evidence of infection. in northern thailand, the seroprevalence was 58 per cent and the prevalent serovars were leptospira interrogans serovar sejroe, leptospira interrogans serovar tarassovi, leptospira interrogans serovar ranarum and leptos ...	2007	17369477
prevalence of rabies virus infection and rabies antibody in stray dogs: a survey in bangkok, thailand.	to investigate the rabies antigen and antibody prevalences among stray dogs in bangkok, thailand, we took both a saliva and serum sample from each of 3314 stray dogs captured once each between december 2003 and june 2004. one 2-year-old female was antigen positive in the latex-agglutination test and confirmed by reverse transcription-polymerase chain reaction. the overall antibody seroprevalence from the enzyme-linked immunosorbent assay that we used was 62% (95% ci: 54, 70%). antibody seropreva ...	2007	17141896
seroprevalence of toxoplasma gondii antibodies in stray cats and dogs in the bangkok metropolitan area, thailand.	cats and dogs are the most popular pet animals worldwide. cats are the natural reservoir of toxoplasma gondii and excrete the resistant oocyst to environments. on the other hands, dogs play a role in the mechanical transmission of the parasite. stray cats and dogs in the bangkok metropolitan area are becoming a public concern because there is a considerable increase in their number annually. these facts indicate the risk of mechanically spreading zoonoses including toxoplasmosis to humans since ...	2007	17141415
canine parasitic zoonoses in bangkok temples.	fecal samples were collected from 204 humans and 229 dogs from 20 different temples in bangkok, as well as communities in the surrounding temple ground areas. human and dog stool samples were examined for intestinal parasites including giardia using zinc sulfate flotation and microscopy. hookworms were the most common parasite in dogs (58.1%) followed by trichuris (20.5%), isospora (10%), giardia (7.9%), toxocara (7.4%), dipylidium caninum (4.4%) and spirometra (3.1%). blastocystis hominis (5.9% ...	2007	17539273
analysis of gyra mutations related to quinolone resistance in escherichia coli isolates originating from pet, human, vegetable and ice in bangkok and vicinity.	escherichia coli was used to investigate quinolone resistance and mutations in gyra gene of e. coli isolated from pet (dog and cat), human (pet's owner), vegetable and edible ice in bangkok and vicinity. susceptibility test for nalidixic acid (na) showed similar percent resistance among the sample sources but a lower ciprofloxacin (cip) resistance was found particularly in human source. mutations within quinolone resistance determining region of gyra gene analyzed using non-radioactive single-st ...	2007	18613552
stray dogs in bangkok, thailand: rabies virus infection and rabies antibody prevalence.	in thailand, the animal most reported rabid is the stray dog. dog bite related rabies cases in humans account for 70-95% of rabies related deaths. the reported incidence of dog bites is highest in the central part of the country, especially in bangkok. this epidemiological survey shows that at least five different canine rabies virus types are present in bangkok. rabies antigen and antibody prevalence in stray dogs in bangkok was also investigated. saliva and serum samples were taken from 3,314 ...	2008	18634473
pcr-based coprodiagnostic tools reveal dogs as reservoirs of zoonotic ancylostomiasis caused by ancylostoma ceylanicum in temple communities in bangkok.	a survey of gastrointestinal parasites of dogs and humans from temple communities in bangkok revealed that 58% of dogs and 3.4% of humans, among those sampled, were infected with hookworms utilising faecal flotation techniques and microscopy. a previously established polymerase chain reaction (pcr)-rflp approach was utilised to determine the species of hookworms infecting dogs found positive for hookworm eggs. single infections with ancylostoma ceylanicum and ancylostoma caninum were recorded in ...	2008	18556131
the prevalence of positive intradermal allergy tests in 114 dogs with atopic dermatitis in the bangkok metropolis, thailand.	intradermal allergy tests using 47 selected local aero-allergens were performed on 114 dogs with atopic dermatitis. the subject animals visited the dermatology unit at the veterinary teaching hospital of kasetsart university or the slv pet hospital with chronic pruritus and various skin lesions. allergen extracts were composed of: 4 house dust and house dust mites, 7 household insects, 24 pollens, 11 mold spores, and kapok. the prevalence of sensitization to various allergens were as follows: de ...	2008	18783836
transmission cycles of giardia duodenalis in dogs and humans in temple communities in bangkok--a critical evaluation of its prevalence using three diagnostic tests in the field in the absence of a gold standard.	the prevalence and associated risk factors for giardia duodenalis in canine and human populations in temple communities of bangkok, thailand were determined by evaluating three common diagnostic methods utilised to detect giardia, namely zinc sulphate flotation and microscopy, an immunofluoresence antibody test and nested polymerase chain reaction (pcr) based on the ssu-rdna gene. the diagnostic sensitivity and specificity together with the negative and positive predictive values of each test we ...	2009	19524080
coinfection of leptospira spp and toxoplasma gondii among stray dogs in bangkok, thailand.	leptospirosis and toxoplasmosis are zoonotic diseases with global importance. asymptomatic animals harboring these pathogens may act as carriers to other animals including humans. the objective of this study was to investigate the seroprevalence of leptospira and toxoplasma infections in stray dogs in bangkok. a total of 230 stray dogs from monasteries in a bangkok district were examined for specific antibodies to t. gondii and leptospira. the seroprevalence of t. gondii was determined by a modi ...	2009	19323009
prevalence of bartonella infection in cats and dogs in a metropolitan area, thailand.	the prevalence of bartonella infection was studied in 312 cats and 350 dogs in the bangkok metropolitan areas, thailand, between june 2001 and february 2003. bartonella was isolated from 47 (16.3%) of 288 stray cats, but from none of the 24 pet cats studied. of the 47 bartonella-positive cats, 45 animals were infected with only b. henselae, one was infected with only b. clarridgeiae, and one with both b. henselae and b. clarridgeiae. 16s rrna typing showed that 40 cats were infected with b. hens ...	2009	19379541
enrichment culture and molecular identification of diverse bartonella species in stray dogs.	using pre-enrichment culture in bartonella alpha-proteobacteria growth medium (bapgm) followed by pcr amplification and dna sequence identification that targeted a fragment of the citrate synthase gene (glta), we provide evidence of common bartonella infections and diverse bartonella species in the blood of stray dogs from bangkok and khon kaen, thailand. the overall prevalence of all bartonella species was 31.3% (60/192), with 27.9% (31/111) and 35.8% (29/81) in the stray dogs from bangkok and ...	2010	20570065
rickettsia, ehrlichia, anaplasma, and bartonella in ticks and fleas from dogs and cats in bangkok.	abstract flea and tick specimens (5-10 fleas or ticks) on dogs and cats from various sites in bangkok were tested by polymerase chain reaction and dna sequencing to detect dna of bacteria rickettsia (glta and 17 kda genes), anaplasmataceae (16s rrna gene), and bartonella (pap31 and its genes). we confirmed that rickettsia sp. related to rickettsia felis was detected in 66 of 98 (67.4%) flea specimens from dogs, whereas 8 bartonella henselae and 2 bartonella clarridgeiae were detected in 10 of 54 ...	2011	21612535