Publications

serological and immunohistological assessment of epstein-barr virus infection in sicilian patients with suspected nasopharyngeal carcinoma.	an evaluation of antibodies to epstein-barr virus (ebv) was carried out on 18 patients with suspected nasopharyngeal carcinoma (npc). with one exception, 9 patients, with histologically confirmed npc, had high levels of igg and iga antibodies to ebv-related antigens, vca and ea. out of 4 patients, without histologically confirmed npc and an antibody pattern compatible with the disease, one developed npc 22 months later. these data confirm the usefulness of serological markers as a diagnostic aid ...	1988	2841559
hla-b8,dr3 phenotype and the antibody response against epstein-barr virus.	antibodies against the viral capsid antigen (vca) and nuclear antigens (ebnas) of the epstein-barr virus (ebv) were determined in a sample of sicilian population. a significant correlation was observed between hla-b8,dr3 phenotype and reduced titres of antibodies to ebnas, whereas hla-b8,dr3 positive individuals displayed levels of antibodies to vca comparable to those of hla-b8,dr3 negative ones. these results further strengthen the suggestion that hla-b8,dr3 positive subjects are low responder ...	1993	8382661
impact of cmv and ebv seropositivity on cd8 t lymphocytes in an old population from west-sicily.	herpes viruses (particularly cmv and to some extent ebv) might play a role in accelerating the deterioration of immune functions with age. indeed, it has been demonstrated that chronic infection with cmv causes an expansion of specific cd8 t lymphocytes and that this is related to a shrinkage of the t cell repertoire in very elderly people, predicting mortality. we have analysed cd8 t cells in young and old healthy sicilians who were both cmv- and ebv-seropositive. our data confirm expansions of ...	2007	17611062
differences in kaposi sarcoma-associated herpesvirus-specific and herpesvirus-non-specific immune responses in classic kaposi sarcoma cases and matched controls in sicily.	kaposi sarcoma (ks) might develop because of incompetent immune responses, both non-specifically and specifically against the ks-associated herpesvirus (kshv). peripheral blood mononuclear cells from 15 classic (non-aids) ks cases, 13 kshv seropositives (without ks) and 15 kshv-seronegative controls were tested for interferon-+¦ t-cell (enzyme-linked immunospot [elispot]) responses to kshv-latency-associated nuclear antigen (lana), kshv-k8.1 and cmv/epstein-barr virus (ebv) peptide pools. the fo ...	2011	21740480