Publications

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characterization of extended-spectrum beta-lactamase (esbl)-producing kuwait and uk strains identified by the vitek system, and subsequent comparison of the vitek system with other commercial esbl-testing systems using these strains.two hundred and fifty-one unique patient isolates of klebsiella pneumoniae (123), escherichia coli (114), klebsiella oxytoca (7), enterobacter cloacae (5) and citrobacter freundii (2), flagged as extended-spectrum beta-lactamase (esbl) positive by the vitek system (gns-526 card), were collected. these strains were isolated from a variety of clinical specimens submitted to the clinical bacteriology laboratories of the royal infirmary of edinburgh (rie), edinburgh, uk (and associated gp practices) ...200616533989
first report of a novel extended-spectrum beta-lactamase koxy-2 producing klebsiella oxytoca that hydrolyses cefotaxime and ceftazidime.klebsiella oxytoca strains mu946294n and mb193997e were isolated from patients in scotland. strain mu946294n was resistant to pencillins, monbactams and cephalosporins. isolate mb193997e displayed a +¦-lactam resistance phenotype consistent with chromosomal +¦-lactamase overproduction. no bla(tem), bla(shv) or bla(ctx-m) genes could be amplified in either strain; however, amplification by pcr was found with primers for the bla(oxy-2) gene. this +¦-lactamase gene in mu946294n differed by one muta ...201121742579
non-susceptibility of escherichia coli, klebsiella spp., pseudomonas spp., streptococcus pneumoniae and staphylococcus aureus in the uk: temporal trends in england, northern ireland, scotland and wales.to monitor and compare trends in the non-susceptibility of bloodstream isolates of pathogens to key antibiotics in the constituent countries of the uk between 2010 and 2014.201626892779
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