Publications

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zika virus. 024983096
genetic and serologic properties of zika virus associated with an epidemic, yap state, micronesia, 2007.zika virus (zikv) is a mosquito-borne flavivirus first isolated in uganda from a sentinel monkey in 1947. mosquito and sentinel animal surveillance studies have demonstrated that zikv is endemic to africa and southeast asia, yet reported human cases are rare, with <10 cases reported in the literature. in june 2007, an epidemic of fever and rash associated with zikv was detected in yap state, federated states of micronesia. we report the genetic and serologic properties of the zikv associated wit ...200818680646
zika virus outbreak on yap island, federated states of micronesia.in 2007, physicians on yap island reported an outbreak of illness characterized by rash, conjunctivitis, and arthralgia. although serum from some patients had igm antibody against dengue virus, the illness seemed clinically distinct from previously detected dengue. subsequent testing with the use of consensus primers detected zika virus rna in the serum of the patients but no dengue virus or other arboviral rna. no previous outbreaks and only 14 cases of zika virus disease have been previously d ...200919516034
zika virus outside africa.zika virus (zikv) is a flavivirus related to yellow fever, dengue, west nile, and japanese encephalitis viruses. in 2007 zikv caused an outbreak of relatively mild disease characterized by rash, arthralgia, and conjunctivitis on yap island in the southwestern pacific ocean. this was the first time that zikv was detected outside of africa and asia. the history, transmission dynamics, virology, and clinical manifestations of zikv disease are discussed, along with the possibility for diagnostic con ...200919788800
[when some flaviviruses are throwing our certainties].during the past two decades, a number of mosquito-borne flaviviruses, mainly of african origin, have invaded new geographical areas where they have never been active. this was the case for the japanese encephalitis virus which reached the northeastern part of australia (1995) and, above all, for the west nile virus which, since 1999, entirely colonized the american continent. then, the usutu virus invaded a large part of the western europe (2001) while the zika virus caused a large epidemic in a ...201222923343
genetic characterization of zika virus strains: geographic expansion of the asian lineage.zika virus (zikv) is a mosquito-borne flavivirus distributed throughout much of africa and asia. infection with the virus may cause acute febrile illness that clinically resembles dengue fever. a recent study indicated the existence of three geographically distinct viral lineages; however this analysis utilized only a single viral gene. although zikv has been known to circulate in both africa and asia since at least the 1950s, little is known about the genetic relationships between geographicall ...201222389730
aedes hensilli as a potential vector of chikungunya and zika viruses.an epidemic of zika virus (zikv) illness that occurred in july 2007 on yap island in the federated states of micronesia prompted entomological studies to identify both the primary vector(s) involved in transmission and the ecological parameters contributing to the outbreak. larval and pupal surveys were performed to identify the major containers serving as oviposition habitat for the likely vector(s). adult mosquitoes were also collected by backpack aspiration, light trap, and gravid traps at se ...201425299181
current zika virus epidemiology and recent epidemics.the zika virus (zikv) is a mosquito-borne flavivirus (aedes), similar to other arboviruses, first identified in uganda in 1947. few human cases were reported until 2007, when a zika outbreak occurred in yap, micronesia, even though zikv activity had been reported in africa and in asia through virological surveillance and entomological studies. french polynesia has recorded a large outbreak since october 2013. a great number of cases and some with neurological and autoimmune complications have be ...201425001879
comparative analysis of dengue and zika outbreaks reveals differences by setting and virus.the pacific islands of micronesia have experienced several outbreaks of mosquito-borne diseases over the past decade. in outbreaks on small islands, the susceptible population is usually well defined, and there is no co-circulation of pathogens. because of this, analysing such outbreaks can be useful for understanding the transmission dynamics of the pathogens involved, and particularly so for yet understudied pathogens such as zika virus. here, we compared three outbreaks of dengue and zika vir ...201627926933
origin of the zika virus revealed: a historical journey across the world.zika virus (zikv) is an arbovirus within the flaviviridae family, the recent spread of which has promoted public concern.201627650823
zika virus and glut1. 201627184421
zika virus in the americas: a review for clinicians.zika virus has recently emerged as a new public health threat. an arthropod-borne virus named after the zika forest in uganda, it was first discovered in 1947. the virus caused only sporadic cases of zika infection in africa and southeast asia until 2007, when the first large outbreak occurred in the yap state in the federated states of micronesia. another outbreak in french polynesia in 2013 was notable for being associated temporally with an increase in cases of guillain-barré syndrome. in 201 ...201627046524
transmission potential of zika virus infection in the south pacific.zika virus has spread internationally through countries in the south pacific and americas. the present study aimed to estimate the basic reproduction number, r0, of zika virus infection as a measurement of the transmission potential, reanalyzing past epidemic data from the south pacific.201626923081
zika virus. 201626895850
zika virus: an update on epidemiology, pathology, molecular biology, and animal model.zika virus (zikv) was first described in 1947, and became a health emergency problem in 2016 when its association with fetal microcephaly cases was confirmed by centers for disease control and prevention (cdc) in the united states. to date, zikv infection has been documented in 66 countries. zikv is recognized as a neurotropic virus and numerous diseases manifested in multiple neurological disorders have been described, mainly in countries that have been exposed to zikv after the 2007 outbreak i ...201627124623
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