Publications

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evidence for transmission of pseudomonas cepacia by social contact in cystic fibrosis.pulmonary colonisation with pseudomonas cepacia in patients with cystic fibrosis can be associated with increased morbidity and mortality. the modes of transmission of p cepacia are, however, unclear. we used selective media and phenotypic and genomic typing systems to investigate the acquisition of p cepacia by adults with cystic fibrosis. an analysis of isolates from 210 patients attending regional clinics in edinburgh and manchester between 1986 and 1992 showed that the main cause of increase ...19937686239
the emergence of a highly transmissible lineage of cbl+ pseudomonas (burkholderia) cepacia causing cf centre epidemics in north america and britain.the rapid increase in pseudomonas (burkholderia) cepacia infection in cystic fibrosis (cf) patients suggests epidemic transmission, but the degree of transmissibility remains controversial as conflicting conclusions have been drawn from studies at different cf centres. this report provides the first dna sequence-based documentation of a divergent evolutionary lineage of p. cepacia associated with cf centre epidemics in north america (toronto) and europe (edinburgh). the involved epidemic clone e ...19957585148
antibiograms of resistant gram-negative bacteria from scottish cf patients.over a 19-month pilot phase, 93 multiply resistant gram-negative isolates from scottish cystic fibrosis patients were sent to a referral laboratory for further investigation.200415463901
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