Publications

[statistical analyses of the annual examination data for yusho in fukuoka].		1983	6411575
fetal pcb syndrome: clinical features, intrauterine growth retardation and possible alteration in calcium metabolism.	pregnant mothers with yusho in fukuoka, nagasaki and kochi prefectures delivered babies with a peculiar clinical manifestation which will be called fetal pcb syndrome (fps). the birth rate incidences were 3.6% (fukuoka prefecture), 4% (nagasaki prefecture), 2.9% (kochi prefecture) and 3.9% (total). the manifestations consisted of dark brown pigmentation of the skin and the mucous membrane, gingival hyperplasia, exophthalmic edematous eye, dentition at birth, abnormal calcification of the skull a ...	1985	3921362
a cohort study on mortality of "yusho" patients: a preliminary report.	in 1968, a mass food poisoning (yusho) occurred in western japan involving more than 1,850 people, the majority of whom were residents of fukuoka and nagasaki prefectures. the poisoning is now understood to have been caused by ingestion of a commercial brand of rice oil contaminated with polychlorinated derivatives of biphenyls, dibenzofurans, quaterphenyls, and some other related compounds. the number of deaths seen among 1,761 victims (887 males and 874 females) from the date of official regis ...	1987	3147283
[introduction of the information processing system of medical examinations of yusho patients and some results obtained by the 1986 survey].	information processing system for newly established, unified medical examinations of yusho patients which started in september 1985 was presented. some comparative analysis was also shown on the "important findings" in yusho patients residing in fukuoka or nagasaki prefecture. in the 1986 survey, fukuoka male patients showed higher percentages of pigmentation in toe nail, gingiva and palpebral conjunctiva than nagasaki (p less than 0.01), whereas nagasaki male patients showed higher percentages ...	1989	2501202
[analysis of 209 pcb congeners by high separation gas chromatography/low resolution mass spectrometer].	all pcb congeners were analyzed by high separation gas chromatography/low resolution mass spectrometer, using 209 pcb congeners as standards. they were separated into 169 peaks, including 28 peaks containing 2 pcbs and 8 peaks containing 3 pcbs. the rice oil samples of fukuoka and taiwan poisonings were analyzed for pcb congeners. they showed 115 separated peaks of pcb congeners. total pcb concentrations were 879 and 769 ppm in 2 samples of fukuoka rice oil and 57 and 83 ppm in 2 samples of taiw ...	1999	10396875
methanoculleus chikugoensis sp. nov., a novel methanogenic archaeon isolated from paddy field soil in japan, and dna-dna hybridization among methanoculleus species.	a strictly anaerobic, irregularly coccoid, methanogenic archaeon, strain mg62t (= jcm 10825t = dsm 13459t), was isolated from paddy field soil in chikugo, fukuoka, japan. the cells stained gram-negative, were 1.0-2.0 microm in diameter, were lysed by sds and hypotonic solutions and were flagellated. motility was not observed. the strain was able to use h2/co2, 2-propanol/co2, formate, 2-butanol/co2 and cyclopentanol/co2 as substrates for methanogenesis, but did not utilize acetate, ethanol, meth ...	2001	11594593
sex ratio in offspring of those affected by dioxin and dioxin-like compounds: the yusho, seveso, and yucheng incidents.	sex ratios in the offspring of those affected by dioxins or dioxin-like compounds have been reported from seveso, italy and yucheng, taiwan. the sex ratio of live births in yusho, japan after a similar accidental massive exposure to polychlorinated biphenyls (pcbs) and polychlorinated dibenzofurans (pcdfs) in 1968 are reviewed. data on all births among parents exposed to the compounds from 1968 to 1977 in fukuoka and a region of nagasaki, the two areas affected, are reported. in total there were ...	2001	11452050
[a longitudinal analysis on the association of serum lipids and lipoproteins concentrations with blood polychlorinated biphenyls level in chronic "yusho" patients].	we examined the association between blood pcb level and the serum concentrations of total cholesterol, high-density lipoprotein cholesterol and triglycerides. the data was retrieved from the dataset of the nationwide health examination for yusho patients. we longitudinally analyze the laboratory data of the officially identified yusho patients who underwent the health examination in fukuoka and nagasaki prefectures five times or more during the years from 1986 to 2000. for the longitudinal analy ...	2003	12872711
[peculiar remaining of some pcb congeners in the patients with yusho for more than 30 years].	concentrations of polychlorinated biphenyl (pcb) congeners, hexachlorobenzene (hcb) and dichloro dichlorophenyl ethylen (dde) in the blood of yusho patients (n = 28) were statistically compared with those in the blood of fukuoka residents (n = 151). the pcb concentrations in the blood of yusho patients were higher than those of fukuoka controls and concentration ratios of yusho/control were various depending on pcb congeners, being 1.6 on 2,3',4,4',5-pentacb (# 118), 17.5 on 2,3,3',4,4',5-hexacb ...	2003	12872714
[follow-up survey of dioxins in the blood of yusho patients (in 2001)].	follow-up survey of the blood concentration of polychlorinated dibezo-p-dioxin (pcdds), polychlorinated dibenzofuran (pcdfs), non-ortho-coplaner pcbs (non-co-pcb), and mono-ortho-coplaner pcbs (mo-co-pcb) in yusho patients is very important for their health control. we determined the blood concentration of these dioxin-like isomers in 78 blood samples collected in 2001 using by a high-resolution gas chromatograph/high-resolution mass spectrometer (hrgc/hrms) equipped with a solvent-cut large vol ...	2003	12872713
follow-up survey of dioxin concentrations in the blood of yusho patients in 2002-2003.	we measured the concentrations of polychlorinated dizenzo-p-dioxins (pcdds), polychlorinated dibenzofurans (pcdfs), and non-ortho-coplanar polychlorinated biphenyls (co-pcbs) in blood collected from 279 yusho patients and 92 yusho-suspected persons living in japan in 2002, 269 yusho patients and 74 yusho-suspected persons living in japan in 2003 and 128 normal controls living in fukuoka prefecture, and compared with the concentrations of these compounds among the groups. the total teq concentrat ...	2005	15997781
[evaluation of dermatological symptoms of yusho patients in the annual examination in 2003-2004].	we evaluated the severity grades and the skin severity scores of the skin symptoms who visited the annual examinations of fukuoka prefecture in 2003 and 2004. the severity of skin symptoms improved significantly in the first 20 years; nowadays, however, further improvement can hardly be observed. more than 36 years have passed since the yusho incident, and about 60% of the patients currently present no skin symptoms. in contrast, in about 40% of the patients, characteristic skin symptoms of yush ...	2005	15997776
[trend of pcb/pcdf concentrations in the blood of yusho patients for 38 years after the incidence].	concentrations of 2,3',4,4',5-pentacb (pcb118), 2,2',4,4',5,5'-hexacb (pcb153), 2,3,3',4, 4',5-hexacb (pcb156) and total pcb congeners (pcbs) in the blood of yusho patients, surveyed by the annual medical examination in fukuoka prefecture, have been gradually decreased from 1974 (7 ppb) to 2006 (3 ppb). the patients are classified into 3 types of yusho, namely, yusho a: having typical yusho gas chromatogram (gc) pattern, yusho b: between yusho a and yusho c, and yusho c: having gc pattern simila ...	2007	17642296
[blood pcb concentrations and their characteristics examined in fukuoka 2006 annual inspection for yusho].	we analyzed sixty-eight pcb isomers and determined their concentrations and characteristics in fifty-eight individual blood samples collected during the annual yusho inspection in 2006. the method used in this study consists of a rapid gpc clean-up and sensitive pcb isomer-specific identification with hrgc/hrms. as a result, the highest total pcb concentration in inspected subjects was 6.6 ppb on a blood weight basis, which was 8.1 times higher than that of a control blood sample. when blood pcb ...	2007	17642295