Publications

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hyperreactive malarial splenomegaly in venezuela.a cross-sectional seroepidemiological survey seeking hyperreactive malarial splenomegaly was carried out in isolated yanomami hamlets in amazonas territory in venezuela. all 110 inhabitants greater than 1 year of age were evaluated clinically and 98 were studied immunologically. the spleen index for individuals greater than 10 years of age was 44%. only 3 patients had plasmodium spp. on thick blood smears. all had serological evidence of infection with plasmodium falciparum and p. vivax. twenty- ...19883041852
diagnosis of malaria by acridine orange fluorescent microscopy in an endemic area of venezuela.fluorescent (acridine orange) microscopical examination of capillary centrifuged blood (quantitative buffy coat [qbc] analysis) and giemsa stained thick blood smears (gts) were compared for diagnosis of malaria in blood specimens from adults living in malaria transmission areas of the states of bolivar and amazonas in southeastern and south venezuela, respectively. of a total of 198 gts examined, 95 subjects (48%) showed parasitaemia. among the 95 blood films with a positive gts, 94 were judged ...19968734954
comparison of the diagnosis of malaria by microscopy, immunochromatography and pcr in endemic areas of venezuela.whole blood samples (n = 295) were obtained from different locations in amazonas and sucre states, in venezuela. malaria was diagnosed by microscopy, optimal and polymerase chain reaction (pcr), with plasmodium vivax, p. falciparum, and p. malariae being detected when possible. we identified 93 infections, 66 of which were caused by p. vivax, 26 by p. falciparum, and 1 was a mixed infection. no infection caused by p. malariae was detected. the sensitivity and specificity of each diagnostic metho ...200717401497
a rapid malaria appraisal in the venezuelan amazon.while the federal state of amazonas bears the highest risk for malaria in venezuela (2007: 68.4 cases/1000 inhabitants), little comprehensive information about the malaria situation is available from this area. the purpose of this rapid malaria appraisal (rma) was to provide baseline data about malaria and malaria control in amazonas.200920003328
assessment of routine malaria diagnosis in the venezuelan amazon.the quality of routine malaria diagnosis is a crucial topic of malaria control. the aim of this assessment was to monitor and evaluate the quality of routine malaria diagnosis in amazonas (venezuela) and to improve the quality control system. the traditional non-blinded quality control system was found to be overburdened with diagnostic samples. a modified sampling system with fewer samples to be tested was proposed. expert microscopists blindly double-checked 1000 slides and 550 rapid diagnosti ...201121376357
malaria seroprevalence in blood bank donors from endemic and non-endemic areas of venezuela.in venezuela, a total of 363,466 malaria cases were reported between 1999-2009. several states are experiencing malaria epidemics, increasing the risk of vector and possibly transfusion transmission. we investigated the risk of transfusion transmission in blood banks from endemic and non-endemic areas of venezuela by examining blood donations for evidence of malaria infection. for this, commercial kits were used to detect both malaria-specific antibodies (all species) and malaria antigen (plasmo ...201121537669
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