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helicobacter pylori infection and atrophic gastritis. a case-control study in a rural town of japan.we enrolled five hundred twenty-one patients with atrophic gastritis and 769 controls in a case-control study of atrophic gastritis and helicobacter pylori infection and lifestyle factors. the participants had no history of upper gastrointestinal surgery. they were selected from 1,395 adult (35 years or older) residents of a rural town in kyoto prefecture who participated in an annual health examination in 1987. atrophic gastritis was diagnosed on the basis of serum pepsinogen levels: pepsinogen ...19979412931
relationship between helicobacter pylori icea, caga, and vaca status and clinical outcome: studies in four different countries.there is continuing interest in identifying helicobacter pylori virulence factors that might predict the risk for symptomatic clinical outcomes. it has been proposed that icea and caga genes are such markers and can identify patients with peptic ulcers. we compared h. pylori isolates from four countries, looking at the caga and vaca genotypes, icea alleles, and presentation of the infection. we used pcr to examine icea, vaca, and caga status of 424 h. pylori isolates obtained from patients with ...199910364597
regional differences in metronidazole resistance and increasing clarithromycin resistance among helicobacter pylori isolates from japan.the patterns of antibiotic resistance in helicobacter pylori were assessed in two different regions in japan. overall, prevalences of resistance to metronidazole and clarithromycin were 12.4 and 12.9%, respectively. while there was no difference in clarithromycin resistance, the prevalence of metronidazole resistance was significantly higher in kyoto (23.8%) than in sapporo (8.1%). from 1996 to 1999, the prevalence of metronidazole resistance did not change but the prevalence of clarithromycin r ...200010898707
prescreening of a high-risk group for gastric cancer by serologically determined helicobacter pylori infection and atrophic gastritis.though gastric cancer screening by x-ray examination has been confirmed to be effective for reducing gastric cancer mortality, decreases in efficiency have been pointed out. establishment of an effective screening system, focusing on high-risk status such as helicobacter pylori infection and atrophic gastritis, is desirable. to date, combined use of serum anti-helicobacter pylori antibodies and pepsinogen measurement has been assessed prospectively in participants in opportunistic and workplace ...201020204698
kyoto global consensus report on helicobacter pylori gastritis.to present results of the kyoto global consensus meeting, which was convened to develop global consensus on (1) classification of chronic gastritis and duodenitis, (2) clinical distinction of dyspepsia caused by helicobacter pylori from functional dyspepsia, (3) appropriate diagnostic assessment of gastritis and (4) when, whom and how to treat h. pylori gastritis.201526187502
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