Publications

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california encephalitis virus. serologic survey of small wind mammals in northern united states and southern canada and isolation of additional strains. 196314043542
a case of encephalitis in a human associated with a serologic rise to jamestown canyon virus.an 8-year-old girl living in rural southwestern michigan experienced sudden onset of symptoms beginning with headache, dizziness and fever which rapidly progressed to central nervous system involvement with seizures and coma. following 27 days of hospitalization her recovery was uneventful, with no apparent sequelae 15 months after discharge. serologic studies of paired sera showed a rise in antibody to jamestown canyon virus, a member of the california serogroup (family bunyaviridae). specific ...19827149109
jamestown canyon virus: the etiologic agent of an emerging human disease? 19836191343
prevalence of neutralizing antibody to jamestown canyon virus (california group) in populations of elk and moose in northern michigan and ontario, canada.blood samples were collected from free-ranging elk (cervus elaphus) harvested in michigan's northern lower peninsula, from moose (alces alces) relocated from ontario's algonquin provincial park to michigan's upper peninsula, and from moose from michigan's isle royale national park. sera were tested by serum dilution neutralization tests in vero cell culture for neutralizing antibody to california serogroup viruses, in particular jamestown canyon (jc), la crosse/snowshoe hare (lac/ssh), and trivi ...19863503129
jamestown canyon virus (california serogroup) is the etiologic agent of widespread infection in michigan humans.in a sample population of 780 michigan residents tested for neutralizing antibodies to california serogroup viruses, 216 (27.7%) had specific neutralizing antibody to jamestown canyon virus. an additional eight (1.0%) had specific neutralizing to trivittatus virus; none had specific neutralizing antibody to la crosse virus. significantly more male residents than female residents of the lower peninsula had antibody to jamestown canyon virus. the frequency of neutralizing antibody titers fits the ...19863953951
isolation of cache valley virus and detection of antibody for selected arboviruses in michigan horses in 1980.blood samples collected in september and november 1980 from 87 horses in southwestern michigan were examined for virus isolation and for plaque-reduction neutralizing antibody against selected arboviruses. cache valley virus was isolated from the blood of a clinically normal horse in st joseph county in september. the age-specific antibody prevalence for cache valley virus indicated enzootic transmission in the study area. the high antibody prevalence and the lack of age-specific antibody preval ...19873631684
infection of white-tailed deer (odocoileus virginianus) in michigan with jamestown canyon virus (california serogroup) and the importance of maternal antibody in viral maintenance.sera collected from a captive population of white-tailed deer (odocoileus virginianus) penned in the lower peninsula of michigan were assayed over a 29-mo period for neutralizing antibody to california serogroup viruses. in all, 130 individual white-tailed deer were bled one to 22 times between june 1983 and november 1985. of the 130 sampled after active transmission had ceased, or passage of maternal antibody in colostrum had occurred, only one (0.8%), a newborn fawn, had no serum neutralizing ...19873102763
isolation of jamestown canyon virus (california serogroup) from aedes mosquitoes in an enzootic focus in michigan.twenty isolates of jamestown canyon virus were obtained from adult females of 5 aedes species collected at the houghton lake wildlife research area, missaukee county, in north-central michigan between 1985 and 1989. fourteen were from aedes provocans, and 6 were from 4 other snowmelt aedes species. one isolate of trivittatus virus and one cache valley-like virus were also obtained. seasonal succession patterns for numerous mosquito species were recorded over 4 years. the temporal association of ...19902230774
serological evidence of california group and cache valley virus infection in minnesota white-tailed deer.blood samples were obtained from 138 white-tailed deer (odocoileus virginianus) harvested at three sites surrounding the greater minneapolis-st. paul, minnesota, metropolitan area (usa) and tested for neutralizing antibody to cache valley virus and three california serogroup (jamestown canyon, la crosse, trivittatus) viruses (bunyaviridae). deer at each site had neutralizing antibody to one or more california serogroup viruses and/or cache valley virus. the majority of adult deer (85%) had antib ...19911906113
genetic relationships of jamestown canyon virus strains infecting mosquitoes collected in connecticut.jamestown canyon virus (jcv) (family bunyaviridae, genus orthobunyavirus) is maintained in a mosquito-deer cycle and has been implicated in the etiology of meningitis and encephalitis with human cases reported from ontario, canada, michigan, connecticut, and new york. despite the recognition of symptomatic cases in the northeastern united states, little is known about the genetic relationships of jcv variants circulating in this region. accordingly, we compared the phylogenetic relationships of ...200718165540
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