Publications

united states aids activity.	the tables in this report present data on cases reported to the centers for disease control by may 26, 1986, of acquired immunodeficiency syndrome (aids). as of that date, a total of 21,065 cases (20,771 involving adults and 294 involving children under 18 years of age) had been reported. 11,541 (55%) of aids victims have died. the majority of cases in both the adult and pediatric populations have involved pneumocystis carinii pneumonia without kaposi's sarcoma. 47% of aids cases have occurr ...	1986	12267771
neoplastic complications of htlv-iii infection. lymphomas and solid tumors.	neoplastic disease arose in 29 of 200 patients infected with human t lymphotropic virus type iii (htlv-iii) seen at a suburban hospital. seventeen patients had kaposi's sarcoma, one of whom also had colon carcinoma. nine patients had lymphoproliferative disorders (seven lymphomas, one t suppressor cell chronic lymphocytic leukemia, and one multiple myeloma), including three with concomitant kaposi's sarcoma and one with colon cancer. one other patient had colon cancer, one had a seminoma, and on ...	1987	3493690
effect of t4 count and cofactors on the incidence of aids in homosexual men infected with human immunodeficiency virus.	we prospectively evaluated potential markers and cofactors for the acquired immunodeficiency syndrome (aids) in 86 homosexual men who were seropositive for human immunodeficiency virus antibodies. during three years of follow-up, 19 men developed aids. risk of aids was clearly predicted by the total number of circulating okt4-positive lymphocytes (t4 count) at enrollment, while the corresponding t8 count was unrelated to subsequent aids development. subjects in manhattan had a higher risk of kap ...	1987	3491911
changes in the epidemiology of non-hodgkin's lymphoma associated with epidemic human immunodeficiency virus (hiv) infection.	the extent to which the epidemic of human immunodeficiency virus (hiv) infection has changed the descriptive epidemiology of cancers other than kaposi's sarcoma is unknown. this study, based on cancer surveillance data (new york state cancer registry) and mortality statistics (new york city death certificates), examines changes in the epidemiology of another hiv-related malignancy, non-hodgkin's lymphoma. since the beginning of the epidemic of acquired immunodeficiency syndrome (aids), there hav ...	1988	3421237
acquired immunodeficiency syndrome.	a report entitled "kaposi's sarcoma and pneumocytosis carinii pneumonia among homosexual men in new york city and california" in the mmwr in july 1981 alerted the world to the appearance of a completely new disease. the opportunistic infections and cancers occurring in these patients had previously only been seen in patients who were immunosuppressed. homosexual men were the first as a major risk group to be identified. others quickly followed. the pattern of occurrence clearly indicated an infe ...	1989	2599843
risk factors for kaposi's sarcoma in the vancouver lymphadenopathy-aids study.	in our ongoing cohort study of homosexual men, the ratio of new kaposi's sarcoma (ks) cases to new opportunistic infections (oi) during the periods 1982-1985, 1986-1987, and 1988-1989 fell from 0.75 (9 ks: 12 oi) to 0.57 (12 ks:21 oi) to 0.27 (4 ks:15 oi), respectively. to examine factors associated with the development of ks as compared to oi, we compared antecedent risk factors in 25 ks cases and 48 oi "controls." in univariate analyses, several classical hiv risk factors including numbers of ...	1990	2395081
kaposi's sarcoma in three hiv-1-infected cohorts.	we describe the kaposi's sarcoma (ks) experience in three cohorts of homosexual men, subjects with hemophilia, and human immunodeficiency virus type 1 (hiv-1) seroconverters. the risk of ks was higher in hiv-1-infected homosexual men from new york city as compared with washington, d.c. and was very low in the hemophilia subjects. while ks accounted for a decreasing proportion of aids cases in homosexual men, the absolute risk per year did not diminish. survival was similar after diagnosis of ks ...	1990	2395084
immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific.	since prevalent cohorts may be biased by the duration of human immunodeficiency virus (hiv) infection (onset bias), it is useful to assess the potential predictive value of markers in incident cohorts of hiv-positive subjects for whom the date of seroconversion is known or can reliably be estimated. of 131 homosexual men with hiv-1 seroconversion from new york city and washington, dc, who were evaluated annually beginning in 1982, 60 developed acquired immunodeficiency syndrome (aids) by the end ...	1992	1384311
cancer incidence trends in women at high risk of human immunodeficiency virus (hiv) infection.	to determine the types and rates of tumors which may be associated with hiv infection in women, we used cancer incidence data from new york and northern new jersey. we examined changes in incidence of selected cancers in women aged 20-49 years and compared groups differing in incidence of aids. black women were compared to white women in new york city and in the remainder of new york state; for cervical cancer, rates were also compared for blacks and whites in northern new jersey. the incidence ...	1993	8370617
survival and mortality patterns of an acquired immunodeficiency syndrome (aids) cohort in new york state.	the survival experience and causes of death of acquired immunodeficiency syndrome (aids) patients were studied using a cohort of 3,699 aids patients in new york state, excluding new york city, whose illness was diagnosed before january 1990 at age 13 years or older. the median length of survival for all cases was 11.5 months, and survival increased over time from 5.3 months pre-1984 to 9.3 months in 1984-1986 and to 13.2 months in 1987-1989. in a cox proportional hazards model, risk of dying was ...	1993	8356973
progression of human immunodeficiency virus type 1 (hiv-1) infection among homosexual men in hepatitis b vaccine trial cohorts in amsterdam, new york city, and san francisco, 1978-1991.	the authors evaluated the progression of human immunodeficiency virus type 1 (hiv-1) disease from the date of seroconversion to the development of acquired immunodeficiency syndrome (aids) and death among 362 well-documented seroconverters. the participants were homosexual men in hepatitis b vaccine trials in amsterdam (n = 74), new york city (n = 120), and san francisco (n = 168). there were significant differences in the proportion of deaths, mean age at seroconversion, and mean age at aids di ...	1994	8192140
increased incidence of cancer among homosexual men, new york city and san francisco, 1978-1990.	several studies have shown that human immunodeficiency virus type 1 (hiv-1) is associated with an increase in the incidence of kaposi's sarcoma and non-hodgkin's lymphoma among homosexual men. the role of hiv-1 in increasing the incidence of other malignancies is more controversial. the incidence of non-kaposi's sarcoma cancer was examined from 1978 to 1990 among 15,565 homosexual men who participated in studies of hepatitis b virus infection in the late 1970s in new york city, new york, and san ...	1996	8916502
antibodies to human herpesvirus 8 in women and infants born in haiti and the usa.	146 hiv-1-positive pregnant women and 143 matched hiv-1-uninfected pregnant women participated in a study to assess the association of human herpes virus 8 (hhv8) and the development of kaposi's sarcoma. 98 of the 189 evaluable infants born to the women were born to hiv-1-positive mothers; 26 of these 98 infants were infected with hiv-1. maternal serum samples were available for all but 18. the sera were diluted and screened for antibodies to the hhv8 latency-associated nuclear antigens (lana ...	1997	9149705
human immunodeficiency virus-associated pericardial effusion: report of 40 cases and review of the literature.	human immunodeficiency virus (hiv)-associated pericardial effusion is common. we present its clinical features, cause, and prognosis on the basis of a review of 40 cases at a single public hospital.	1999	10047635
evidence for concurrent epidemics of human herpesvirus 8 and human immunodeficiency virus type 1 in us homosexual men: rates, risk factors, and relationship to kaposi's sarcoma.	we examined human herpesvirus 8 (hhv-8) seroprevalence and seroincidence among 245 homosexual men from new york city (nyc) and washington, dc (dc) who have been followed since 1982. an immunofluorescence assay measured antibodies to a latent hhv-8 nuclear antigen. seroprevalence was 20.4% in 1982; seroincidence was approximately 15%/year during 1982-1983 but fell sharply thereafter. nyc men had a higher seroprevalence (odds ratio, 3.43; p<.001) and seroincidence (rate ratio, 2.13; p=.01) than dc ...	1999	10479125
human herpesvirus 8 infection and kaposi's sarcoma among human immunodeficiency virus-infected and -uninfected women.	little is known about the epidemiology of human herpesvirus 8 (hhv-8) infections among women. a cross-sectional study was conducted of hhv-8 infection among human immunodeficiency virus (hiv)-infected and high-risk hiv-uninfected women. serological tests with noninduced (latent) and induced (lytic) hhv-8 antigens were used to detect infection among 2483 participants of a multisite cohort. reactivity to latent antigen was present in 4.1% and to induced antigens in 12.0% of women. seven of 8 women ...	2001	11237842
kaposi's sarcoma-associated herpesvirus infection in elderly jews and non-jews from new york city.	worldwide, kaposi's sarcoma (ks) occurs in immunocompetent elderly adults, especially men. elderly jews have relatively high ks risk, but it is unclear whether this indicates heightened prevalence of ks-associated herpesvirus (kshv), the ks agent. we studied jewish and non-jewish patients at a new york city geriatrics clinic.	2002	12435765