Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| cultivation of measles virus in stable line of human amnion cells. | 1958 | 13554467 | |
| electron-dense crystallites in nuclei of human amnion cells infected with measles virus. | 1960 | 13796031 | |
| observations of measles virus infection of human cells. iii. correlation of properties of clones of h.ep.-2 cells with their susceptibility to infection. | 1960 | 14436277 | |
| studies on attenuated measles vaccine. i. clinical and immunologic response to measles virus attenuated in human amnion cells. | 1962 | 14449564 | |
| ender's live measles-virus vaccine with human immune globulin. ii. evaluation of efficacy. | 1962 | 13907410 | |
| studies of live attenuated measles virus vaccine in man. ii. appraisal of efficacy. | 1962 | 13907411 | |
| studies of live attenuated measles virus vaccine in man. i. clinical aspects. | 1962 | 13917383 | |
| virus isolation, inclusion bodies, and chromosomes in a rubella-infected human embryo. | 1963 | 14044275 | |
| demonstration of human measles antibody by mixed agglutination. | 1963 | 14050201 | |
| viremia: isolation of measles virus from the washed leukocytic fraction of human blood. | 1963 | 14089829 | |
| [culture of human thyroid cells and its application to the study of some myxoviruses]. | 1963 | 14104842 | |
| the development of a continuous cell line from normal dog liver and its susceptibility to viruses. lf-10. | 1963 | 14163348 | |
| rubella antibodies in human serum: detection by the indirect fluorescent antibody technic. | antibodies for rubella virus were detected in human serum and titrated by the indirect method of immunofluorescence; a chronically infected, continuous line of monkey kidney cells was used as antigen. positive reactions were obtained with serums from convalescent patients or persons who had been exposed to the virus while serums from patients in the acute stage of the disease and those from unexposed individuals were negative | 1964 | 14163822 |
| influence of various viruses on the heterotransplantability of human cells. | 1964 | 14170129 | |
| changes in aldolase activity following infection with certain viruses. | 1964 | 14209625 | |
| attempt to establish a diploid cell strain from human embryonic tissue and testing its sensitivity to some viruses. | 1964 | 14209631 | |
| antiviral activity of gliotoxin and gliotoxin acetate. | 1964 | 14254440 | |
| a study of the antigenic relationship between human measles virus and canine distemper virus. | 1965 | 14299038 | |
| antibodies to respiratory syncytial virus in human sera from different regions of the world. | since it was first isolated in 1956, respiratory syncytial (rs) virus has been found in many parts of the world, generally in association with human respiratory illness, especially of young children. previous studies have examined the frequency of serological evidence of infection in certain countries. the present study is a more general survey, dealing with the prevalence of rs virus antibody in sera from 14 different countries widely separated geographically. there was evidence of infection in ... | 1965 | 5294309 |
| virological studies on chromosome damage of hela cells induced by myxoviruses. | 1966 | 4290662 | |
| [a comparative study of some biological properties of measles virus in human thyroid cell culture]. | 1966 | 5924351 | |
| virus infections of the upper respiratory tract (abridged). | 1969 | 4303221 | |
| transformation of cells cultured from human brain tissue. | 1969 | 4309380 | |
| characteristics of a human diploid cell designated mrc-5. | 1970 | 4316953 | |
| virus-induced chromosome pulverization in human diploid cells. | 1970 | 4317262 | |
| some properties of a new epithelial cell line of human origin. | 1970 | 4317734 | |
| viruses and chromosomes. | 1970 | 4320571 | |
| polykaryocytosis and mitosis in a human cell line after treatment with measles virus. | 1970 | 5525758 | |
| antibodies to various herpesviruses in sera from patients with sarcoidosis. | 1971 | 4328945 | |
| the effect of a carbobenzoxy tripeptide on the biological activities of measles virus. | 1971 | 4332971 | |
| chronic viral infections of the central nervous system. | 1971 | 4940819 | |
| [on antiviral antibodies in urine. v]. | 1972 | 4343290 | |
| viral antibodies in the mano tribe of northern liberia. | 1972 | 4344187 | |
| the use of cord serum and indirect viral immunofluorescence as a method of evaluating the immunological specificity of fluorescein-labelled anti-human iga conjugate. | 1973 | 4348667 | |
| a seroepidemiological study of epstein-barr virus and other viral antigens in sarcoidosis. | 1973 | 4349694 | |
| [transfer factor of cellular immunity. preliminary therapeutic trials during specific immunologic deficiencies of an antigen in human clinical practice]. | 1973 | 4351886 | |
| virus-specific immunoglobulins in multiple sclerosis. | 1973 | 4353489 | |
| [properties of the rh cell line]. | 1973 | 4357539 | |
| [pathogenic organisms of infectious heart diseases]. | 1973 | 4360233 | |
| virus antibodies in patients with multiple sclerosis. | 1973 | 4365526 | |
| [virologic-diagnostic studies in unclear exanthema]. | 1973 | 4751441 | |
| replication or inactivation of different viruses by human lymphocyte preparations. | cultures of phytohemagglutinin-stimulated, unstimulated, and frozen and thawed mononuclear (as controls) cells from normal human donors were infected with different viruses. a variable pattern of virus infectivity was noted, and influenza and coxsackie virus were rapidly inactivated even by stimulated lymphocytes. direct inactivation by lymphocytes may be one form of host defense in infection by some viruses. | 1974 | 4361296 |
| viral infections of the central nervous system. | 1974 | 4362722 | |
| a serological study on mentally ill patients with particular reference to the prevalence of herpes virus infections. | 1974 | 4365487 | |
| letter: cytomegalovirus in non-b post-transfusion hepatitis. | 1974 | 4139618 | |
| characteristics of secretory immune system in human middle ear: implications in otitis media. | 1974 | 4205203 | |
| virus antibody levels in serum specimens from patients with optic neuritis and from matched controls;. | virus antibody levels in serum specimens taken in acute and convalescent phases from 77 patients with optic neuritits were tested by measles hamagglutination inhibition (hi), measles hemolysis inhibition (hli), rubella hi, parainfluenza-1 hi, epstein-barr immunofluorescence (if), and against 11 other viruses and mycoplasma pneumoniae with the complement fixation (cf) technique. the virus antibody levels were indicated to be usually very stable, and a fourfold change in virus antibody levels was ... | 1975 | 165652 |
| newer knowledge in comparative virology--its contribution to human health research. | like other comparative sciences, and despite its recent beginning comparative virology has already contributed useful applications and observations to human health research. teachings derived from the study of marek's disease found application in that of burkitt's lymphoma, and may lead to a possible vaccine against the human disease. equally useful information came from the study of canine distemper in the development of a chorio-allantoic membrane attenuated measles vaccine, and in our knowled ... | 1975 | 167504 |
| virologic studies in rheumatoid arthritis. | comparison of virus antibody titers in jra and matched controls failed to implicate rubella, measles, parainfluenza type 1 or epstein-barr viruses. neither rna viruses or mycoplasma were detected in rheumatoid synovial cell cultures by 3h-uridine incorporation. mycoplasma were not isolated from rheumatoid synovial membranes or cell cultures using the large specimen-broth culture procedure. the balance of available evidence, including our own, suggests that mycoplasma are not involved in ra. viru ... | 1975 | 173010 |
| effect of adsorbents on igm and igg measles antibodies. | sera from rabbits immunized with l-16 measles virus absorded with monkey blood cells; kaolin and blood cells; and mncl2 and heparin were examined in haemagglutination inhibition (hi) and neutralization tests. kaolin and mncl2 adsorbed primarily hi igm antibodies from the early immunization period. the adsorbents used had no influence on hi and neutralization igg antibodies. human convalescent serum gave similar results, i.e. only igg antibodies were found and they were not affected by kaolin and ... | 1975 | 1989 |
| letter: lymphocyte agglutination in multiple sclerosis. | 1975 | 52801 | |
| letter: measles-virus-induced migration inhibition of human leucocytes: an immunologically unspecific phenomenon? | 1975 | 53765 | |
| the mutagenic effect of measles virus on cell cultures of different origin. | differences between strains of measles virus in their mutagenic effect on cells of different animals and man were found. the mutagenic activity of measles virus strains was species-specific. in the process of spontaneous transformation the sensitivity of cells to the mutagen changed. | 1975 | 241227 |
| identification of measles virus-specific hemolysis-inihibiting antibodies separate from hemagglutination-inhibiting antibodies. | the occurrence of antibodies giving hemolysis inhibition (hli) but not hemagglutination inhibition (hi) was examined in human convalescent and rabbit hyperimmune sera. hi antibodies, which through their interaction with hemagglutinin components display hli activity, were removed by absorption with tween 80-ether (te)-treated measles virus material. this absorption did not change the titer of non-hi hli antibodies. after removal of hi antibodies from 16 late measles convalescent sera and three ba ... | 1975 | 803467 |
| inhibition of lymphocyte stimulation by measles virus. | the effect of measles virus on phytohemagglutinin-(pha) induced stimulation of human peripheral blood mononuclear cells was investigated to delineate possible mechanisms for viral suppression of cell-mediated immunity (cmi). it was noted that medium which had several days contact with uninfected monolayers as well as unpurified measles virus preparations produced significant inhibition of 3h-thymidine incorporation by pha-stimulated lymphocytes. when partially purified measles virus preparations ... | 1975 | 804515 |
| structural homogeneity of human subacute sclerosing panencephalitis antibodies. | three homogeneous immunoglobulin fractions were isolated from the serum of a patient with subacute sclerosing panencephalitis (sspe). all three fractions reacted in immunodiffusion with measles and sspe virus preparations. the amino-terminal sequence of the light and heavy chains of one of the antibody fractions was determined by automated edman degradation. a single amino acid residue was obtained at every step, confirming the homogeneity of this human antibody. | 1975 | 807623 |
| measles virus receptor on human t lymphocytes. | 1975 | 1079923 | |
| chromosome aberrations in cells infected with various strains of measles virus. | the incidence of chromosome fragmentation and/or breakage has been studied in cultured human embryonic diploid cells infected with different wild and vaccinal strains of measles virus. it seemed that for wild strains the mean incidence of fragmentation was two times higher, that of breakage two times lower than for the vaccinal strains. | 1975 | 1089353 |
| characterization of measles virus-specific cytotoxic antibodies by use of a chronically infected cell line. | the complement-dependent cytotoxic effects of measles virus specific antibodies on a chronically infected cell line were studied by a microcytotoxicity assay. cell damage was determined by trypan blue staining. monospecific antisera against the hemagglutinin (ha) and the hemolysin (hl) of the virus were both cytotoxic. rabbits, immunized with measles virus, developed cytotoxic antibodies in parallel with the appearance of antibodies against the measles virus ha and hl. human sera with high antib ... | 1975 | 1089724 |
| measles antibodies and immunoglobulins in sera from patients with subacute sclerosing panencephalitis (sspe) and from an infected ferret. | cellulose acetate electrophoresis of sera from 2 patients with sspe revealed a slow-moving and a fast-moving gamma-globulin band. the igg fractions from sera were isolated by the combination of starch block electrophoresis, sephadex gel filtration and isoelectric focusing techniques. the purity of each protein was tested by immunoelectrophoresis using a potent goat anti-whole human serum. the isolated igg preparations were tested in hi, cf and n tests against measles virus envelope, measles viru ... | 1975 | 1185233 |
| measurement of virus antigens on the surface of hela cells persistently infected with wild type and vaccine strains of measles virus by radioimmune assay. | persistent states of measles virus infection have been established in hela cells by using edmonston strain virus and two types of measles virus vaccine (m-vac and schwarz). the absolute amount of surface viral antigens expressed on these cells infected separately with the three viruses has been assessed by a newly developed method which employs [125i]-labelled fab fragments of immunoglobulin g (igg) from immune human sera. this method was used to determine the level of viral antigenic expression ... | 1976 | 1255135 |
| transient appearance of oligoclonal immunoglobulins and measles virus antibodies in the cerebrospinal fluid in a case of acute measles encephalitis. | acute measles encephalitis with severe sequelae in a 25-year-old man was studied. a transient appearance of oligoclonal igg in cerebrospinal fluid and of intrathecally produced measles antibodies was found during 2 months after the onset of the disease. on the basis of this finding of local hyperimmunization it is proposed that in the case studied the measles virus infection may have been directly responsible for the disease process in the central nervous system. | 1976 | 947643 |
| measles virus-induced migration inhibition of human leukocytes in vitro: an expression of cell-mediated immunity? | attempts were made to establish measles virus-induced migration inhibition of human leukocytes as an in vitro test of cell-mediated immunity to the virus. crude material from cell cultures infected with two different strains of measles virus was used as antigen in the capillary modification of the test. both virus preparations induced migration inhibition. incubation with puromycin indicated that the inhibition was dependent on protein synthesis, which has been regarded as a characteristic featu ... | 1976 | 996451 |
| purification of host dna synthesis-suppressing factor (dsf) produced by infection with measles virus. | host dna synthesis-suppressing factor (dsf) produced into culture fluid of cloned hela cells (hela c-9) infected with a small plaque variant of toyoshima strain of measles virus was purified by precipitation with ammonium sulfate, chromatography on cm-cellulose and deae-cellulose, and gel-filtration on sephadex g-100 and g-200. the specific activity of the finally purified dsf was 302 units/mg of protein representing approximately 300-fold purification. the molecular weight of dsf was estimated ... | 1976 | 1018343 |
| [effect of infectious factors on human and animal cytogenetic structures]. | the analysis of blood leucocyte chromosomes has been carried out on 60 patients with different infectious diseases (influenza, measles, scarlet fever, and disentery), and on 47 patients immunized against measles, tick-born encephalitis, typhoid fever and brucellosis. the mutagenic influence of viruses on the genital cells of mice and on the human somatic cells in vitro was studied. both viruses and bacteria appeared to be able to bring about different breaks in human and animal cells. | 1976 | 1027162 |
| immunologic injury in measles virus infection. iii. presence and characterization of human cytotoxic lymphocytes. | human peripheral blood leukocytes (pbl) from patients with chronic measles virus infection (sspe) or from immune, adult humans (convalescent from acute childhood measles virus infection) are cytotoxic for target cells infected with measles virus as measured by a 51cr assay. specific release of 51cr by immune pbl occurred both with and without human antibodies added to measles virus-infected cultures. maximal killing in the absence of added antibodies to measles virus was usually detected only af ... | 1977 | 830751 |
| the formation and fate of virus antigen-antibody complexes. | we report the fate of 125i human igg measles virus antibodies complexed to virus antigens expressed on the surfaces of hela cells persistently infected with measles virus. each hela cell expressing viral antigens on its surface bound about 7.5 x 106 igg molecules under saturation conditions. three hours after 125i antiviral igg bound to and saturated all antigenic sites on infected cells, 30% of the counts were released (85% tca ppt), after 12 hr 60%, and after 24 hr 75% (30% tca ppt). by linear ... | 1977 | 830754 |
| subacute sclerosing panencephalitis: experimental infection in primates. | measles virus isolated from the brain of a 12-year-old boy with subacute sclerosing panencephalitis caused a chronic, progressive encephalitis in experimentally infected rhesus monkeys. the infection was eventually fatal in spite of pre-existing measles immunity and a vigorous secondary antibody response in serum and cerebrospinal fluid of the infected animals. the findings provide a basis for studies into the pathogenesis and possible treatment of the human disease. | 1977 | 831255 |
| an in vitro study of the susceptibility of cells from a meningioma of human origin for measles virus. | a cell culture from a meningioma of human origin was found permissive for the edmonston strain of measles virus. virus was isolated from the supernatant of infected cell sheet as soon as 48 hr post-inoculation. cytopathic effect, observed by light microscopy, exhibited syncitia plus intracytoplasmic and intranuclear inclusions. electron microscopy enabled viral nucleocapsids to be observed first in the cytoplasm and secondly within the nucleus of infected cells. | 1977 | 859012 |
| replication of measles virus in a cell culture from a glioblastoma of human origin. | a cell culture from a glioblastoma of human origin infected with the edmonston strain of measles virus produced and released infectious measles virus. all cellular types seemed to be involved in the process of virus replication. staining with hematin-eosin revealed the presence of eosinophilic intracytoplasmic and intranuclear inclusions. examination with the electron microscope revealed viral nucleocapsids in the cytoplasm and, rarely, in the nuclei of infected cells. | 1977 | 894326 |
| rubella antibodies and acute viral hepatitis. | high antibody titres against rubella and measles viruses have recently been associated with certain chronic disorders such as chronic active hepatitis and occasionally with acute hepatitis. the present study was designed to evaluate the frequency of this association with acute hepatitis. haemagglutination inhibition (hi) and complement fixation (cf) antibodies to rubella, measles and influenza a viruses were determined in 97 consecutive patients with acute viral hepatitis and in 97 control perso ... | 1977 | 905781 |
| antibody-modification of measles "in vitro" infection. | while the involvement of measles-like virus with subacute sclerosing panencephalitis (sspe) has been shown in many laboratories, the possible mechanisms by which a normal measles infection may lead to the chronic condition are unclear. the work reported here demonstrates that the growth and maintenance of vero cells infected with the mv 30 strain of measles, in the presence of multivalent antibody, results in a redistribution of the viral antigens within the cells and an alteration in the proper ... | 1977 | 417148 |
| interactions between human lymphocytes and paramyxovirus-infected cells: adsorption and cytotoxicity. | the capacity of human lymphocytes to adhere to paramyxovirus-infected monolayers and their capacity to kill paramyxovirus-infected cells was investigated. a large fraction of human lymphocytes was found to adhere firmly to the paramyxovirus-infected monolayers. predsorption of lymphocytes on mumps virus-infected cells impaired their adsorption to a second cell monolayer of the same type. the cytotoxic activity of lymphocytes against mumps virus-infected cells was also reduced after predsorption ... | 1977 | 300397 |
| adherence of human peripheral blood lymphycytes to measles-infected cells. enhancement by prostaglandin e1. | we studied the effect of prostaglandins in vitro on an immune reaction mediated by t cells; adherence of lymphocytes to measles-virus-infected human epithelial cells. normal human lymphocytes adhered to a mean +/- s.d. 20.1 +/- 5.2 per cent of these hep-2 cells. the percentage positive cells increased to 50.3 +/- 5.7 when lymphocytes were incubated with 10(-6) m prostaglandin e1 (p less than 0.01 vs. untreated lymphocytes); 10(-8) m and 10(-10) m were as effective. prostaglandin f2alpha had no e ... | 1977 | 194153 |
| morphology of human cells, carrier of measles virus, using nomarski optics and scanning electron microscopy. | a human cell line (lu106) carrier of measles virus was studied in a nomarski interference-contrast microscope (nicm) and a scanning electron microscope (sem). the results from this were correlated with fine structure findings obtained from analyses made in the transmission electron microscope (tem). in both the nicm and sem it was possible to identify intracellular perinuclear structures, which most likely represent aggregates of measles nucleocapsids. these structures appeared in the nicm as op ... | 1977 | 194389 |
| subacute sclerosing panencephalitis (sspe) agent in hamsters. | a hamster-adapted sspe agent was shown to cause a productive infection in weanling hamster brain, which changed to a cell-associated or defective infection coincident with the appearance of measles antibodies in serum. antibodies to measles hemagglutinin, hemolysin and neucleocapsid antigens developed in serum, which also contained neutralizing activity for regular measles virus. the agent recovered from the brains prior to the appearance of serum antibodies was infectious in cell-free media, ca ... | 1977 | 99679 |
| epstein-barr virus-associated and other antiviral antibodies during intense bcg administration to patients with burkitt's lymphoma in remission. | patients with burkitt's lymphoma in chemotherapy-induced remission received through dermal scarifications one or two doses per week of approximately 3 x 10(8) living bcg organisms (pasteur institute vaccine). this treatment was always followed by usually rapid increases by 1--4 log2 steps in the antibody titers to epstein-barr virus (ebv)-associated cell membrane antigens. titer increases of less than 2.5 log2 steps within the first month after the start of bcg treatment correlated with a signif ... | 1978 | 203706 |
| immunologic "memory" for microbial antigens in lymphocytes obtained from human bronchial mucosa. | memory for previous immunologic contact with microbial antigens has been detected in lymphocytes from human bronchi as a secondary immune response, when tested in vitro. antigens stimulated a predominantly proliferative response in blood lymphocytes that was significantly greater than the response in mucosal lymphocytes with purified protein derivative and herpes simplex type 1 antigens. co-culture experiments with autologous blood lymphocytes showed that cell-dependent suppression was one mecha ... | 1978 | 204236 |
| hyporesponsiveness of lymphocytes to virus antigens in rheumatoid arthritis. | the immune response of peripheral blood lymphocytes to measles, rubella, parainfluenza types 1, 2, and 3 rna virus antigens and to varicella-zoster and herpes virus type 1 dna virus antigens was evaluated in 14 patients with rheumatoid arthritis (ra) and 14 matched controls by assessing 3h-thymidine incorporation. the results demonstrated hyporesponsivenss of lymphocytes from ra patients to virus antigens and phytohemagglutinin (pha), which did not appear to be nonspecific because of a lack of c ... | 1978 | 205223 |
| serological studies in the elderly. | sera from 108 elderly patients in psychiatric and general hospitals were tested for antibodies to seven viruses. measles virus antibody levels were significantly higher in patients from the psychiatric hospital, regardless of diagnosis, than in those from other hospitals. demented patients, regardless of their hospital, had significantly higher levels of antibody to adenovirus than control patients. | 1978 | 208409 |
| isolation of a heterogeneous population of temperature-sensitive mutants of measles virus from persistently infected human lymphoblastoid cell lines. | two human lymphoblastoid b-cell lines, wi-l2 and 8866, were infected with the edmonston strain of measles virus at a multiplicity of infection of 10(-6), and stable persistent infections were established. by immunofluorescence and electron microscopy, the vast majority of cells from both cell lines were expressing viral antigens and releasing virion-like particles. however, very little infectious virus could be detected at 37 degrees c, either by an infectious centers assay or by titration of su ... | 1978 | 210247 |
| virus infection in demyelinating diseases. | several animal and human demyelinating diseases of the central nervous system (cns) are associated with rna or dna viruses. these viruses infect cns cells lytically or persistently. they mainly belong to the group of envelope viruses which derive their envelope partly from the host cell membrane. the process of virus release may result in the appearance of new antigens of virus-infected cells or the incorporation of cell membrane material into the viral envelope. these changes may lead to an imm ... | 1978 | 211825 |
| silver staining and nucleolar patterns in human heteroploid and measles-carrier cells. | 1978 | 80393 | |
| [formation of dna-proviruses in cells of a human transplantable lymphoid line during infection with tick-borne encephalitis viruses or measles virus]. | 1978 | 620634 | |
| complement-dependent cytotoxicity of sera obtained from subacute sclerosing panencephalitis patients. | human lymphoid cells (nc-37) persistently infected with either measles virus (schwarz and tycsa strains) or subacute sclerosing panencephalitis (sspe) virus (halle and mantooth strains) were destroyed in the presence of complement by anti-measles sera as well as by sera from sspe patients. the cytotoxic activity was demonstrated in both igg and igm fractions of measles convalescent sera, but only in igg fraction of sspe sera. measles convalescent sera completely lost the cytotoxic activity to al ... | 1978 | 672673 |
| activation of measles virus from silently infected human lymphocytes. | lymphocytes were incubated with measles virus for 4 days in the absence of a lymphocyte stimulating agent. such nonstimulated lymphocytes, infected with measles virus, did not express the virus antigens that are detectable by cytotoxic antibodies. approximately 1 out of 5,000, or even fewer, of such lymphocytes produced virus as demonstrated by the infectious center assay; in the supernate only 10--100 infectious viruses per milliliter were detected. no virus structures could be observed by mean ... | 1978 | 702064 |
| generation of virus-specific cytolytic activity in human peripheral lymphocytes after vaccination with vaccinia virus and measles virus. | human peripheral blood lymphocytes (pbl) harvested after vaccination with vaccinia or measles virus showed a specific activity against virus-infected target cells. this activity peaked on day 7 and was specific for the target cells infected with the virus used for the vaccination. the cytotoxic activity was not related to hla markers. the cells involved in the cytolytic process were lymphocytes bearing fc receptors. in addition, the cytotoxic activity was abrogated by more than 90% by rabbit fab ... | 1978 | 723792 |
| demonstration of anti-rubella antibody-secreting cells in rheumatoid arthritis patients. | in the present study we describe a plaque-forming cell assay using erythrocytes coated with viral antigen, which detected anti-viral antibody-secreting cells against various viral antigens. these anti-viral antibody-secreting cell were studied in normal individuals with known viral infections and in rheumatoid arthritis patients. rubella anti-viral antibody-secreting cells were present after induction in the peripheral blood of eight out of ten patients. no plaques were seen before induction. sy ... | 1979 | 472665 |
| the binding of protein a of immunoglobulin g and of fab and fc fragments. | results are presented to show that protein a (pa) may fix to the fab region of igg outside the antigen binding site. thus, pa-reactive fab fragments were isolated both from specific anti-egg albumin and specific anti-measles virus antibodies. a probable significance of this fab reactivity in the precipitation reaction between igg and pa is discussed. reactive igg from human, guinea pig, rabbit, and porcine normal sera all showed similar avidity towards pa. slight differences between igg subclass ... | 1979 | 484238 |
| modulation of the adherence of human lymphocytes to measles-infected cells by prostaglandin e1: a differential effect on lymphocyte subpopulations. | prostaglandins of the e series (pge) may serve as important regulators of human immune responsiveness. the present study was designed to examine the possibility that pge may effect human lymphocyte function by the modulation of surface receptors. the presence of surface binding sites on human lymphocytes for measles virus antigens was studied using a rosette adherence assay. we observed that the addition of pge1 increased the proportion of measles-infected cells (hela-kll) with adherent lymphocy ... | 1979 | 523674 |
| adherence of human peripheral blood lymphocytes to measles-virus infected cells: modulation by solubilized rhesus erythrocyte membranes and carbohydrates. | the adherence of human peripheral blood lymphocytes to hela cells persistently infected with measles virus (hela-k11) was studied. the following data were observed. (i) the proportion of hela-k11 cells with adherent human peripheral blood lymphocytes of rhesus monkey erythrocytes was similar over a wide range of ratios of hela-k11 cells to lymphocytes or erythrocytes. (ii) the great majority of human peripheral blood lymphocytes and erythrocytes reacted with the same hela-k11 cell (iii). the adh ... | 1979 | 572346 |
| generation on infected fibroblasts of human t and non-t lymphocytes with specific cytotoxicity, influenced by histocompatibility, against measles virus-infected cells. | 1979 | 87462 | |
| [use of the precipitation reaction for studying viral antibodies in blood sera]. | 1979 | 89261 | |
| affinity for measles virus anti-haemolysin of a residual immunoglobulin m in sera of some patients with multiple sclerosis. | hep2 cells persistently infected with measles virus were treated with trypsin to remove haemagglutinin (ha) and examined unfixed or fixed in acetone by fluorescent antibody methods, comparing those sera specific for structural antigens of the virus. staining patterns combined with the blocking of specific immunofluorescence indicated that igg specific for measles virus haemolysin could be recognized in multiple sclerosis (ms) sera and that in some sera from which rheumatoid factor had been remov ... | 1979 | 383332 |
| measles and subacute sclerosing panencephalitis virus proteins: lack of antibodies to the m protein in patients with subacute sclerosing panencephalitis. | studies on the immunoprecipitation of the proteins of several different measles and subacute sclerosing panencephalitis (sspe) virus strains from lysates of infected cells have revealed a relative lack of antibodies to the nonglycosylated viral membrane protein (m) in the sera of patients with sspe, in contrast to a high level of antibodies to other viral proteins. no evidence was found for the existence of a large number of antigenically unique m proteins. in contrast to sspe sera, other hyperi ... | 1979 | 287042 |
| [modification of a method to study cell fusion induced in vitro by viruses]. | a studying method of viruses induced cell-fusion is described, using monolayers of vero monkey cells. nature and density of cells and infection multiplicity are studied. the sensibility is equal to 4 hemagglutining units of sendaï and accuracy about +/- 3 % of polykaryocytosis. quantification. comparison and kinetics study of cell-fusion are allowed by this method which may lead to systematic and routine exploration of cell-fusion ability of biological extracts from slow degenerative diseases of ... | 1979 | 226237 |
| studies on antiviral glycosides, 4. inhibition of the multiplication of paramyxoviruses by phenyl-6-chloro-6-deoxy-beta-d-glucopyranoside. | the antiviral activity of phenyl-6-chloro-6-deoxy-beta-d-glucopyranoside (pcg) was studied. pcg specifically inhibited the growth of paramyxoviruses including sendai, measles and newcastle disease viruses in llcmk2 cells at a concentration of 0.5 to 1.0 mm, but did not restrict the multiplication of other rna viruses (influenza, vesicular stomatitis and polio viruses) at these concentrations. pcg might act in the late stage during virus replication of sendai virus as it did not inhibit virus rna ... | 1979 | 230307 |
| search for canine-distemper-virus antibodies in multiple sclerosis. a detailed virological evaluation. | sera and cerebrospinal fluid samples from multiple-sclerosis (ms) patients, matched controls, and subacute sclerosing panencephalitis (sspe) patients were analysed for the presence of antibodies specific for measles and canine distemper virus (cdv). virus-specific antibodies were identified by haemagglutination inhibition, neutralisation, and immune precipitation in combination with polyacrylamide-gel electrophoresis. sspe and ms patients had a higher antibody activity towards measles virus than ... | 1980 | 6107454 |
| [studies on establishment and maintenance of persistent infection with measles virus in nc-37 cell. ii. effect of dna-synthesis-suppressing factor (dsf) on the production of interferon in nc-37 cell infected with measles virus (author's transl)]. | the attenuated strain of measles viruses, schwarz, cam-70, or subacute sclerosing panencephalitis (sspe) virus of measles viruses, halle, mantooth was good interferon inducer, but the virulent strain, edmonston, toyoshima induced few amount of interferon or not. furthermore, an inverse relationship seemed to exist between the ability to induce interferon and dna synthesis suppressing factor (dsf). the attenuated strain or sspe virus which had not a capacity to produce dsf could induce interferon ... | 1980 | 6165664 |
| killing of virus-infected cells by cytotoxic lymphocytes. | 1980 | 6249872 |